Endocrinologie/Hormones
Les inhibiteurs en endocrinologie/hormonaux sont des composés qui bloquent l'action des hormones ou interfèrent avec les voies de signalisation hormonales. Ces inhibiteurs sont essentiels pour étudier la régulation des systèmes endocriniens et pour développer des traitements pour les maladies liées aux hormones, telles que le diabète, les troubles de la thyroïde et les cancers hormonodépendants. En modulant l'activité hormonale, ces inhibiteurs peuvent aider à élucider les interactions complexes au sein du système endocrinien. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité en endocrinologie/hormonaux pour soutenir vos recherches en endocrinologie, pharmacologie et sciences médicales.
Sous-catégories appartenant à la catégorie "Endocrinologie/Hormones"
- Récepteur des androgènes(209 produits)
- Annexine A(11 produits)
- Aromatase(20 produits)
- Récepteur d'œstrogène/progestatif(49 produits)
- GPR(1 produits)
- Récepteur des glucocorticoïdes(153 produits)
- LHRH(1 produits)
- Récepteur opioïde(297 produits)
- Récepteur de prostaglandine(120 produits)
- RAAS(87 produits)
- Réductase(52 produits)
- Somatostatine(49 produits)
- Récepteur des hormones thyroïdiennes (THR)(26 produits)
- Récepteur de la vasopressine(44 produits)
Affichez 6 plus de sous-catégories
3183 produits trouvés pour "Endocrinologie/Hormones"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
Raloxifene 4-Monomethyl Ether
CAS :<p>Raloxifene 4-Monomethyl Ether (Compound 37), an estrogen receptor α inhibitor, has an IC50 of 1 μM against MCF-7 cells.</p>Formule :C29H29NO4SCouleur et forme :SolidMasse moléculaire :487.61β-Endorphin, equine TFA
<p>β-Endorphin, equine TFA, an endogenous opioid peptide, demonstrates high affinity binding to μ/δ opioid receptors and possesses analgesic properties [1] [2] [3</p>Formule :C156H249F3N42O46SCouleur et forme :SolidMasse moléculaire :3537.961-Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone
CAS :<p>Methyl-2-quinolone from Evodia rutaecarpa blocks angiotensin II receptor with 48.2 μM IC50.</p>Formule :C25H35NOCouleur et forme :SolidMasse moléculaire :365.55Enalapril
CAS :<p>Enalapril is a dicarbocyl-containing peptide and angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.</p>Formule :C20H28N2O5Degré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :376.455-O-β-D-Glucopyranosylmyricanol
<p>5-O-beta-D-Glucopyranosylmyricanol is a useful organic compound for research related to life sciences and the catalog number is T123967.</p>Formule :C27H36O10Couleur et forme :SolidMasse moléculaire :520.575Ethamoxytriphetol
CAS :<p>Ethamoxytriphetol is a non-steroidal estrogen antagonist.</p>Formule :C27H33NO3Couleur et forme :SolidMasse moléculaire :419.56Glucocorticoids receptor agonist 2
CAS :<p>Arylpyrazole-based glucocorticoid agonist with potent anti-inflammatory effects; doesn't affect insulin secretion.</p>Formule :C25H25FN2OCouleur et forme :SolidMasse moléculaire :388.48SB 205607 dihydrobromide
CAS :<p>non-peptide δ1 opioid receptor agonist</p>Formule :C23H24N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :344.45PSDalpha
<p>PSDalpha, a conjugate of PS, TB, and 17β-estradiol, degrades ERα with peak absorption at 465 nm, effectively inhibiting MCF-7 cell growth.</p>Formule :C44H39N3O2SCouleur et forme :SolidMasse moléculaire :673.86Bufrolin
CAS :<p>Bufrolin is a potent GPR35 agonist, mast cell stabilizer, and anti-inflammatory research agent.</p>Formule :C18H16N2O6Couleur et forme :SolidMasse moléculaire :356.33PD 125967
CAS :<p>PD 125967 is a renin inhibitor, which represents a group of pharmaceutical drugs used primarily to treat essential hypertension.</p>Formule :C51H67N5O4Couleur et forme :SolidMasse moléculaire :814.11Awl 60
CAS :<p>Awl 60 is a substance P (6-11) non-competitive antagonist.</p>Formule :C57H65N9O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1036.25Clocinnamox mesylate
CAS :<p>Clocinnamox mesylate: irreversible μ-opioid blocker; Ki: 0.7 nM (mouse μ), 1.9 nM (δ), 5.7 nM (κ).</p>Formule :C30H33ClN2O7SCouleur et forme :SolidMasse moléculaire :601.11DP50
<p>DP50 is a bifunctional compound containing both an opioid receptor agonist (MOP) and a neuropeptide FF receptor (NPFFR) antagonist. It can be utilized in studies related to analgesia.</p>Formule :C58H72N8O7Masse moléculaire :992.5524GNE-502
CAS :<p>GNE-502 is an orally active and potent estrogen receptor (ER) degrader, specifically designed for research on breast cancer.</p>Formule :C25H30FN3O3SCouleur et forme :SolidMasse moléculaire :471.59CP 85339
CAS :<p>CP 85339 is an aspartic acid protease inhibitor for X-ray analysis of peptide-renin complexes.</p>Formule :C31H49ClN4O6SCouleur et forme :SolidMasse moléculaire :641.26PIPE-3297
<p>PIPE-3297 (compound 25) is a selective kappa opioid receptor (KOR) agonist that activates the G protein signaling pathway with an EC50 of 1.1 nM and exhibits low β-arrestin-2 recruitment activity (10%). Additionally, PIPE-3297 promotes myelination and has anti-inflammatory properties.</p>Formule :C23H30N2OMasse moléculaire :350.23581Zavacorilant
CAS :<p>Zavacorilant is capable of modulating glucocorticoid receptor (GR).</p>Formule :C25H26FN7O3S2Couleur et forme :SolidMasse moléculaire :555.65D3R/MOR antagonist 2
<p>Compound 121, a D3R/MOR antagonist with K i values of 361 nM and 85.2 nM for D3R and MOR respectively, has the potential for analgesic effects through MOR</p>Formule :C25H31ClN2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :410.98VinclozolinM2-2204
<p>VinclozolinM2-2204 is an androgen receptor AUTOTAC degrader with a DC50 of 200 nM in LNCaP prostate cancer cells. It induces the formation of AR+LC3+ autophagic membranes and is applicable for cancer research.</p>Formule :C43H51Cl2N3O9Masse moléculaire :823.30024Angiotensin II (1-4), human
CAS :<p>Angiotensin II constricts blood vessels and boosts blood pressure by escalating norepinephrine release.</p>Formule :C24H37N7O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :551.59[Met5]-Enkephalin, amide
CAS :<p>[Met5]-Enkephalin, amide activates δ and ζ opioid receptors; has multiple forms and varying plasma levels.</p>Formule :C27H36N6O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :572.68TD-802
CAS :<p>TD-802, an AR-targeting PROTAC with microsomal stability, shows promise for castration-resistant prostate cancer.</p>Formule :C52H61ClN10O6Couleur et forme :SolidMasse moléculaire :957.56PROTAC AR Degrader-4 TFA
<p>PROTAC AR Degrader-4: IAP ligand, linker, AR binder; it's a SNIPER that degrades AR non-genetically.</p>Formule :C45H68F3N3O11Couleur et forme :SolidMasse moléculaire :884.03HINT1-IN-1
<p>HINT1-IN-1 (compound 8) is an inhibitor of histidine triad nucleotide-binding protein 1 (HINT1) with a Ki of 1.14 μM. It influences the cross-regulation between μ-opioid receptors (MOR) and NMDA receptors (NMDAR).</p>Formule :C23H24N8O5Couleur et forme :SolidMasse moléculaire :492.49ARD-2585
CAS :<p>ARD-2585 is an orally active and selective androgen receptor PROTAC degrader with anticancer activity for the study of prostate cancer.</p>Formule :C41H43ClN8O5Couleur et forme :SolidMasse moléculaire :763.28Boc-ypgflt(O-tbu)
CAS :<p>Boc-ypgflt(O-tbu) is a delta-receptor-selective opioid antagonist.</p>Formule :C44H64N6O11Couleur et forme :SolidMasse moléculaire :853.01PD 132002
CAS :<p>PD 132002 is a renin inhibitor.</p>Formule :C31H50N4O9SCouleur et forme :SolidMasse moléculaire :654.82Faznolutamide
CAS :<p>Faznolutamide is an antiandrogen agent [1] [2] .</p>Formule :C19H17FN4O2SCouleur et forme :SolidMasse moléculaire :384.43PROTAC ERα Y537S degrader-1
CAS :<p>PROTAC ERα Y537S degrader-1 comprises a ubiquitin E3 ligase binding group, a linker and a protein binding group.</p>Formule :C46H49N5O6Couleur et forme :SolidMasse moléculaire :767.91Nurr1 agonist 9
<p>Nurr1 agonist 9 (Compound 36) acts as an agonist for Nurr1, with an EC50 of 0.090 µM and a Kd of 0.17 µM. It activates Nurr1 homodimers (NurRE, EC50 = 0.094 µM) and Nurr1-RXR heterodimers (DR5, EC50 = 0.165 µM). This compound induces the expression of Nurr1-regulated tyrosine hydroxylase (TH) in Parkinson's disease organoid models and can penetrate the human brain endothelial cell barrier.</p>Formule :C21H19ClN4O2Masse moléculaire :394.11965Bradykinin potentiator-5
CAS :<p>Bradykinin potentiator-5 is a peptide inflammatory mediator, causes blood vessels to dilate (enlarge), and therefore causes blood pressure to fall.</p>Formule :C30H41N7O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :611.69Opioid receptor agonist 1
<p>Opioid receptor agonist1 (Compound 2638-28) is an orally active opioid receptor agonist that shows strong affinity for MOR, DOR, and KOR, with Ki values of 5, 24, and 212 nM, respectively. It exhibits analgesic activity in both the mouse warm water tail-flick model and the acetic acid writhing model.</p>Formule :C32H45N5OCouleur et forme :SolidMasse moléculaire :515.73Ac-RYYRWK-NH2
CAS :<p>Selective NOP receptor partial agonist peptide; Ki=0.71 nM; >4000 nM for μ, δ, κ receptors; boosts food intake in vivo.</p>Formule :C49H69N15O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1012.17ODM-204
CAS :<p>ODM-204 is novel nonsteroidal dual inhibitor of both androgen receptor and CYP17A1 enzyme(IC50s of 80 nM and 22 nM, respectively).</p>Formule :C20H21F3N4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :374.40BigLEN(rat)
CAS :<p>Potent GPR171 agonist (EC50 = 1.6 nM). ProSAAS-derived peptide. Regulates body weight in mice and promotes the outgrowth of neurites in Neuro2A cells.</p>Formule :C76H128N24O23Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1746Epi-Cryptoacetalide
<p>Epi-Cryptoacetalide is a useful organic compound for research related to life sciences and the catalog number is T126054.</p>Formule :C18H22O3Couleur et forme :SolidMasse moléculaire :286.371BWA-6047
<p>BWA-6047 is a dual AR/AR-V7 and GSPT1 PROTAC-type degrader (AR: DC50= 3.7 nM; AR-V7: DC50= 3.0 nM; GSPT1: DC50= 1.2 nM). It facilitates the ubiquitination and degradation of AR/AR-V7 and, through molecular glue properties, induces a PPI between GSPT1 and CRBN, leading to GSPT1 degradation. BWA-6047 is applicable in prostate cancer research.</p>Formule :C42H46ClN5O7Couleur et forme :SolidMasse moléculaire :767.30858MT-7716 hydrochloride
CAS :<p>MT-7716 hydrochloride is a selective agonist of non-peptide nociceptin receptor (NOP)</p>Formule :C27H29ClN4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :477(S,S)-J-113397
CAS :<p>(S,S)-J-113397 is an isomer of J-113397 . J-113397 is an Opioid Receptor antagonist [1] .</p>Formule :C24H37N3O2Couleur et forme :SolidMasse moléculaire :399.57Cgp 29287
CAS :<p>Cgp 29287 is a primate-specific renin inhibitor. It also has a prolonged duration of action.</p>Formule :C72H110N20O15Couleur et forme :SolidMasse moléculaire :1495.77RU-39411
CAS :<p>RU-39411 is a steroidal anti-estrogen.</p>Formule :C28H37NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :435.6015,26-Dihydroxylanosta-7,9(11),24-trien-3-one
CAS :<p>15,26-Dihydroxylanosta-7,9(11),24-trien-3-one is a natural product that can be used as a reference standard. The CAS number of 15,26-Dihydroxylanosta-7,9(11),24-trien-3-one is 420781-85-7.</p>Formule :C30H46O3Couleur et forme :SolidMasse moléculaire :454.7Myrciacetin
CAS :<p>Myrciacetin from Rhododendron inhibits rat aldose reductase with IC50 of 13 μM.</p>Formule :C17H16O6Couleur et forme :SolidMasse moléculaire :316.309PD 123177
CAS :<p>PD 123177 is an inhibitor of Nonpeptide angiotensin AII-2.</p>Formule :C29H28N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :480.56AKR1Cs-IN-1
<p>AKR1Cs-IN-1 (Compound 29) is an effective and broad-spectrum inhibitor of the Aldo-Keto Reductase 1C family (AKR1C1-1C4). It achieves subtype inhibition by simultaneously binding to the SP2 and SP3 pockets, thereby blocking metabolic pathways related to drug resistance. In enzyme assays, AKR1Cs-IN-1 exhibits significant inhibitory activity with IC50 values of 0.09, 0.28, 0.05, and 0.51 µM for AKR1C1, AKR1C2, AKR1C3, and AKR1C4, respectively. The compound shows excellent resensitizing effects in doxorubicin (DOX)-resistant breast cancer cell line MCF-7/ADR, effectively enhancing the cytotoxicity of DOX. AKR1Cs-IN-1 holds promise for research on breast cancer resistance.</p>Couleur et forme :Odour SolidUrotensin II (114-124), human TFA
<p>Urotensin II (114-124), human TFA, is an 11-amino acid peptide and potent vasoconstrictor, acting as GPR14 agonist.</p>Formule :C66H86F3N13O20S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1502.59ZINC05925939
<p>ZINC05925939 is an estrogen receptor β (ESR2) inhibitor used in breast cancer research.</p>Formule :C17H17NO2Couleur et forme :SolidMasse moléculaire :267.32Antidiabetic agent 15
<p>Antidiabetic agent 15 (compound 1B15) acts as a dual inhibitor of AT1R and NEP, reducing oxidative stress and restoring mitochondrial membrane potential.</p>Formule :C26H23NO5Couleur et forme :SolidMasse moléculaire :429.15762Enclomiphene-d4
<p>Enclomiphene-d4 is the deuterium-labeled analog of Enclomiphene. Enclomiphene functions as a potent and orally active estrogen receptor antagonist, exhibiting antiestrogenic properties.</p>Couleur et forme :Odour Solid4',2-Dihydroxy-4,6-dimethoxydihydrochalcone
CAS :<p>4',2-Dihydroxy-4,6-dimethoxydihydrochalcone, an estrogen-like compound, binds to bovine estrogen receptors, IC50 15 μM.</p>Formule :C17H18O5Couleur et forme :SolidMasse moléculaire :302.32LO-4-25
<p>LO-4-25 is a covalent degrader targeting the androgen receptor (AR) and its splice variant AR-V7. It covalently binds to the E3 ubiquitin ligase CUL4 DCAF16, facilitating the ubiquitination of both AR and AR-V7, which are then recognized and degraded by the proteasome, leading to reduced protein levels of AR and AR-V7 in cells. LO-4-25 is promising for research on androgen-independent prostate cancer.</p>Couleur et forme :Odour SolidFrakefamide TFA
<p>Frakefamide TFA: potent, peripherally active μ-opioid agonist; doesn't cross blood-brain barrier.</p>Formule :C32H35F4N5O7Couleur et forme :SolidMasse moléculaire :677.64Methylpiperidino pyrazole
CAS :<p>Methylpiperidino pyrazole is an ERα inhibitor and can prevent the BPS-induced Rb phosphorylation and cell cycle progression.</p>Formule :C29H31N3O3Degré de pureté :98.84%Couleur et forme :SolidMasse moléculaire :469.57Nurr1 agonist 12
<p>Nurr1 agonist 12 (Compound 37) acts as an agonist of the nuclear receptor-related protein 1 (Nurr1), enhancing its transcriptional activity with an EC50 of 0.06 μM. It stimulates human response elements NBRE, NurRE, and DR5 with EC50 values of 0.07 μM, 0.027 μM, and 0.014 μM, respectively. Additionally, Nurr1 agonist 12 induces the expression of neurotrophic genes regulated by Nurr1, such as tyrosine hydroxylase (TH), SOD1/2, BDNF, Sestrin 3, and BIRC5 (Survivin). The compound also demonstrates neuroprotective effects against neurotoxicity caused by Paraquat.</p>Formule :C18H12ClN3OCouleur et forme :SolidMasse moléculaire :321.76GPR88 agonist 2
<p>GPR88 agonist 2 (compound 53) serves as a potent, brain-penetrant agonist of GPR88, exhibiting an EC50 of 14 µM in the GPR88 cAMP functional assay [1].</p>Couleur et forme :Odour SolidOxytocin free acid
CAS :Oxytocin analog with glycine at position 9; impacts health, development, reproduction, behavior.Formule :C43H65N11O13S2Masse moléculaire :1008.18AM-5262
CAS :<p>AM-5262 is a potent GPR40 Full Agonist with improved rat PK profile and general selectivity profile.</p>Formule :C33H35FO4Couleur et forme :SolidMasse moléculaire :514.63ERα degrader 12
<p>ERα degrader12 (Compound RA3) is an estrogen receptor alpha (ERα) degrader with antitumor properties. It significantly suppresses tumor growth in a xenograft mouse model of breast cancer.</p>Formule :C39H41NO9SCouleur et forme :SolidMasse moléculaire :699.81ER degrader 4
CAS :<p>ER degrader 4, a selective and orally active compound, effectively degrades estrogen receptors and exhibits anti-tumor activity [1].</p>Formule :C26H19FO4SCouleur et forme :SolidMasse moléculaire :446.49Nurr1 agonist 5
<p>Compound 5o, a Nurr1 agonist, exhibits neuroprotective properties as a transcription factor Nurr1 agonist, possessing a dissociation constant (Kd) of 0.5 μM and</p>Couleur et forme :Odour SolidEX-A5386
CAS :<p>EX-A5386 (Glucocorticoid receptor modulator-1) is a potent glucocorticoid receptor modulator, IC50/EC50<100nM.</p>Formule :C29H27FN4O2Degré de pureté :99.89%Couleur et forme :SoildMasse moléculaire :482.55Rofleponide
CAS :<p>Rofleponide is a synthetic glucocorticosteroid with a high affinity for the rat thymus glucocorticoid receptor.</p>Formule :C25H34F2O6Degré de pureté :99.32%Couleur et forme :SolidMasse moléculaire :468.537α-(Thiomethyl)spironolactone
CAS :<p>7α-(Thiomethyl)spironolactone is a steroid receptor antagonist and major spironolactone metabolite, steroid metabolism, nuclear receptor, and coronavirus.</p>Formule :C23H32O3SDegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :388.56Bexirestrant
CAS :<p>Bexirestrant is an orally active ER-α degrader commonly employed in the research of antiestrogen and antineoplastic therapies.</p>Formule :C29H26F3NO2Couleur et forme :SolidMasse moléculaire :477.527AKR1C3-IN-9
<p>AKR1C3-IN-9: Selective AKR1C3 inhibitor, IC50=8.92 nM; reverses DOX resistance in breast cancer.</p>Formule :C20H20N2O4Degré de pureté :99.98%Couleur et forme :SoildMasse moléculaire :352.38WAY267464 HCl
CAS :<p>WAY267464: nonpeptide OT agonist, anxiolytic, modulates selectivity, improves CNS entry and oral uptake.</p>Formule :C32H37Cl2N7O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :654.59Galloylalbiflorin
CAS :<p>Galloylalbiflorin, an AR antagonist with IC50 53.3μM, is sourced from Paeonia lactiflora roots, exhibiting anti-androgenic properties.</p>Formule :C30H32O15Couleur et forme :SolidMasse moléculaire :632.57BAY 1003803
CAS :<p>BAY 1003803 is a glucocorticoid receptor agonist for the topical treatment of psoriasis or severe atopic dermatitis.</p>Formule :C21H18ClF5N2O4Couleur et forme :SolidMasse moléculaire :492.83Angiotensin II (5-8), human
CAS :<p>Angiotensin II (5-8) is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin II</p>Formule :C26H36N6O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :512.6Ganoderic acid Df
CAS :<p>Ganoderic acid Df, a lanostane triterpenoid from Ganoderma lucidum, inhibits aldose reductase with IC50 of 22.8 μM.</p>Formule :C30H44O7Couleur et forme :SolidMasse moléculaire :516.67NPFF1-R antagonist 1
<p>NPFF1-R antagonist 1 (compound 8b) is a piperidine analog and an effective neuropeptide FF (NPFF) receptor antagonist. It exhibits 15-fold selectivity for the NPFF1-R subtype, with Ki values of 211 nM and 3270 nM for NPFF1-R and NPFF2-R, respectively.</p>Formule :C37H44N4OMasse moléculaire :560.35151Valorphin
CAS :<p>Valorphin (Valorphin TFAsalt) has opioid analgesic activity, binds to rat mu-opioid receptor, with an IC50 of 14 nM.</p>Formule :C44H61N9O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :892.01Renin FRET Substrate I
CAS :Renin FRET Substrate I, designed for human renin, contains angiotensinogen's N-terminal cleavage site.Formule :C90H120N22O16SMasse moléculaire :1798.15ER ligand-8
CAS :<p>ER ligand-8 is a ligand of the estrogen receptor (Estrogen Receptor/ERR) and can be used for the synthesis of the PROTAC molecule ERD-1233.</p>Formule :C30H27F9O4SCouleur et forme :SolidMasse moléculaire :654.584THR-β agonist 6
CAS :<p>THR-β Agonist 6, a selective and orally active compound targeting the thyroid hormone receptor β (THR-β), demonstrates specificity with EC50 values of 0.03 μM</p>Formule :C20H14Cl2N6O3Couleur et forme :SolidMasse moléculaire :457.27[Arg14,Lys15]Nociceptin
CAS :<p>Potent NOP agonist (EC50 = 1 nM), >875x selective vs opioid receptors; outperforms nociceptin in vivo, increases pain perception, reduces movement.</p>Formule :C82H137N31O22Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1909.18PRO20
<p>PRO20 is a specific and competitive antagonist of the (pro)renin receptor (PRR). It inhibits the calcium influx induced by Proproin with an IC50 value of 81 nmol/L. By blocking the binding of Prorenin to PRR, PRO20 inhibits the activation of the renin-angiotensin system (RAS), reducing the production of angiotensin II (Ang II) and exerting antihypertensive effects. PRO20 holds promise for research in antihypertensive agents.</p>Couleur et forme :Odour SolidCP-472555
CAS :<p>CP-472555 is a selective nonsteroidal glucocorticoid receptor antagonist with anti-GR and anti-obesity activity in animal models.</p>Formule :C31H32N2O2Couleur et forme :SolidMasse moléculaire :464.60Koreanoside E
CAS :<p>Koreanoside E is a useful organic compound for research related to life sciences. The catalog number is T125538 and the CAS number is 1804014-67-2.</p>Formule :C27H30O11Couleur et forme :SolidMasse moléculaire :530.526N-Desmethyl Loperamide
CAS :<p>N-Desmethyl Loperamide is the major metabolite of loperamide. It is also used as the precusor for radiolabelled loperamide.</p>Formule :C28H31ClN2O2Couleur et forme :SolidMasse moléculaire :463.01N-terminally acetylated Endomorphin-1
<p>N-terminally acetylated Endomorphin-1 is a modified Endomorphin-1.</p>Formule :C36H40N6O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :652.74Estrogen receptor modulator 13
<p>Estrogen receptor modulator13 (Compound 5D) is an estrogen receptor antagonist with significant cytotoxic effects on MCF7 cells, exhibiting an IC50 value of 8.50 μM. Estrogen receptor modulator13 holds potential for breast cancer research.</p>Formule :C25H19ClN2O2SCouleur et forme :SolidMasse moléculaire :446.08558DPC-AJ1951 TFA
<p>DPC-AJ1951 TFA is a 14 amino acid peptide, potent PTH/PPR agonist, tested in bone resorption assays.</p>Formule :C78H128F3N23O21Couleur et forme :SolidMasse moléculaire :1781.022-PCCA hydrochloride
CAS :<p>2-PCCA hydrochloride, a racemate, is a potent and selective GPR88 receptor agonist showing inhibition of GPR88-mediated cAMP production in HEK293 cells with an</p>Formule :C30H39Cl2N3ODegré de pureté :97.54% - 99.36%Couleur et forme :SoildMasse moléculaire :528.56Thyroxine sulfate
CAS :<p>Thyroxine sulfate is a sulfoconjugated derivative of Thyroxine and is also a metabolite of Thyroxine.</p>Formule :C15H11I4NO7SCouleur et forme :SolidMasse moléculaire :856.93AL-438
CAS :<p>AL-438 is a non-steroidal selective glucocorticoid receptor modulator.</p>Formule :C23H25NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :347.45Gluten Exorphin B5
CAS :<p>Gluten exorphin B5 (GE-B5) is a food-derived opioid peptide identified in digests of wheat gluten.</p>Formule :C30H38N6O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :594.66ARD-69
<p>ARD-69, a potent PROTAC, degrades AR in prostate cancer, with low DC50 values in AR+ cell lines, and suppresses AR gene expression.</p>Formule :C62H74ClFN8O7SCouleur et forme :SolidMasse moléculaire :1129.83rac-1,2-bis-Palmitoyl-3-chloropropanediol
CAS :<p>3-MCPD ester found in edible oils, highest in olive pomace; toxic to mouse kidneys and spermatids.</p>Formule :C35H67ClO4Couleur et forme :SolidMasse moléculaire :587.37Cebranopadol hemicitrate
CAS :<p>Cebranopadol hemicitrate is a NOP and opioid receptor agonist that targets human NOP, MOP, KOP, and δ-opioid peptide (DOP) receptors, with Ki/EC50 values of 0.9 nM/13 nM, 0.7 nM/1.2 nM, 2.6 nM/17 nM, and 18 nM/110 nM, respectively. It is used in studies of acute and chronic pain.</p>Couleur et forme :SolidTRV-120027
CAS :<p>TRV120027: β-arrestin-1-biased agonist, angiotensin II type 1 receptor, reduces vasoconstriction, boosts heart muscle contraction.</p>Formule :C43H67N13O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :926.09Tetrahydro Aldosterone
CAS :<p>Tetrahydro Aldosterone is a steroidal compound that inhibits the adrenal angiotensin II receptor, with an IC50 of 10 μM.</p>Formule :C21H32O5Couleur et forme :SolidMasse moléculaire :364.48SRD5A1-IN-1
CAS :<p>SRD5A1-IN-1 inhibits SRD5A1 with IC50 of 1.44µM, reducing dihydrotestosterone and SRD5A1 expression.</p>Formule :C17H11F6NO3Degré de pureté :99.74% - 99.77%Couleur et forme :SoildMasse moléculaire :391.27β-Naltrexamine dihydrochloride
CAS :<p>β-Naltrexamine dihydrochloride is an orally administered, irreversible opioid receptor antagonist. Its derivatives exhibit optimised subtype selectivity and can be used for pain research.</p>Formule :C20H28Cl2N2O3Degré de pureté :95.98%Couleur et forme :SoildMasse moléculaire :415.35Ludaterone
CAS :<p>Ludaterone is an antiandrogen agent, with potent antiandrogenic activity.</p>Formule :C20H25ClO5Couleur et forme :SolidMasse moléculaire :380.86Calcitonin, eel
CAS :<p>Calcitonin from eel regulates calcium and is key in studying postmenopausal osteoporosis.</p>Formule :C146H241N43O47S2Degré de pureté :98%Couleur et forme :White PowderMasse moléculaire :3414.91Cl-4AS-1
CAS :<p>steroidal androgen receptor agonist</p>Formule :C26H33ClN2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :441.01PROTAC AR Degrader-9
<p>PROTAC AR Degrader-9 (Compound c6) is a PROTAC-based degrader specifically targeting the androgen receptor. It effectively degrades the androgen receptor in human dermal papilla cells (HDPC) with a DC50 of 262.38 nM. Additionally, this compound enhances the expression of paracrine factors, such as TGF-β1 and β-catenin, thereby promoting hair regeneration in mouse models. [Pink: ligand for target protein AR ligand-38; Black: linker; Blue: ligand for E3 ligase Cereblon]</p>Formule :C43H49ClN6O5Couleur et forme :SolidMasse moléculaire :765.339PRL 2915
CAS :<p>PRL 2915 is a potent antagonist of the human somatostatin subtype 2 receptor (hsst 2), exhibiting a binding affinity (K_i) of 12 nM [1].</p>Formule :C59H71ClN12O8S2Couleur et forme :SolidMasse moléculaire :1175.85CTAP
CAS :<p>Potent μ opioid antagonist, IC50 3.5 nM, 1200x selectivity over δ and somatostatin, brain-penetrant, active in vivo.</p>Formule :C51H69N13O11S2Degré de pureté :98%Couleur et forme :White Solid/PowderMasse moléculaire :1104.32Adrenocorticotropic hormone
CAS :<p>ACTH, a polypeptide, is secreted by the pituitary gland and regulates cortisol and androgen.</p>Couleur et forme :SolidNeuropeptide EI, rat
CAS :<p>Displays functional MCH-antagonist and MSH-agonist activity in different behavioral paradigms.</p>Formule :C63H98N16O23Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1447.55Commendamide
CAS :<p>Commendamide, natural, mimics N-acyl-amides, activates GPR132 with EC50 of 11.8 μM, made by Cbeg12 gene in commensal bacteria.</p>Formule :C18H35NO4Couleur et forme :SolidMasse moléculaire :329.47RG 13647
CAS :<p>RG 13647 is an agonist of angiotensin II peptide.</p>Formule :C30H27N3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :509.55Teriparatide
CAS :<p>Teriparatide is an agonist of PHT(IC50 of 2 nM in HEK293 cells).</p>Formule :C181H291N55O51S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4117.72DDHF20
<p>DDHF20 is an inhibitor of Staphylococcus aureus, specifically targeting and inhibiting its thioredoxin reductase (TrxR) by acting as a competitive inhibitor at the NADPH binding site. DDHF20 shows potential for research in combating infections related to Staphylococcus aureus.</p>Formule :C34H28O4Couleur et forme :SolidMasse moléculaire :500.58Diisononyl phthalate
CAS :<p>Diisononyl phthalate (DINP), known as a plasticizer, is a phthalate. DINP is specifically a mixture of various isononyl esters of phthalic acid.</p>Formule :C26H42O4Couleur et forme :Colorless Liquid In Water (Uscg 1999)Masse moléculaire :418.61PROTAC ER Degrader-3
CAS :<p>PROTAC ER Degrader-3 from patent WO2017201449A1 is a PAC synthesis intermediate for ADC/PROTAC antibody conjugates, boosting ERα degradation.</p>Formule :C71H77N7O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1220.434Alclometasone
CAS :<p>Alclometasone is a glucocorticoid that reduces inflammation and treats various skin conditions like eczema and psoriasis.</p>Formule :C22H29ClO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :408.92Neuropeptide AF (human)
CAS :<p>Neuropeptide AF (93-110), Human is an endogenous antiopioid peptide.</p>Formule :C90H132N26O25Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1978.17Prednisolone farnesylate
CAS :<p>Prednisolone farnesylate is a novel transdermal corticosteroid with anti-inflammatory activity.</p>Formule :C36H50O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :578.78[Sar1, Ile8]-Angiotensin II TFA
<p>[Sar1,Ile8]-Angiotensin II (TFA) contracts arteries and affects cell growth in vascular muscle.</p>Formule :C48H74F3N13O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1082.18[Sar1, Ile8]-Angiotensin II
CAS :<p>[Sar1, Ile8]-Angiotensin II(3TFA) is a peptide that has multiple effects on vascular smooth muscle.</p>Formule :C46H73N13O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :968.15TrxR1 prodrug-1
<p>TrxR1 prodrug-1 (compound 5u) is a potent inhibitor of TrxR1, demonstrating significant antitumor activity in nude mice and NSCLC organoids.</p>Formule :C22H30N2O6S2Couleur et forme :SolidMasse moléculaire :482.613Herkinorin
CAS :<p>Herkinorin: μ-opioid agonist with 100x μ-affinity, 50x less κ-affinity than Salvinorin A, from Salvia divinorum. Semi-synthetic from Salvinorin B.</p>Formule :C28H30O8Couleur et forme :SolidMasse moléculaire :494.53UFP-101
CAS :<p>Strong, selective NOP receptor antagonist with pKi=10.24; >3000x selectivity over δ, μ, κ receptors; blocks nociceptin effects.</p>Formule :C82H138N32O21Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1908.19ERα degrader 10
<p>ERα degrader10 is a potent, selective, orally active estrogen receptor α (ERα) degrader. It demonstrates strong ERα binding affinity (IC50 of 24.0 nM) and degradation capability (EC50 of 5.3 nM). This compound degrades ERα through a proteasome-mediated pathway and is utilized in breast cancer research.</p>Couleur et forme :Odour Solid3-Cl-Pyridine-amide-acrylaldehyde-piperazine
<p>3-Cl-Pyridine-amide-acrylaldehyde-piperazine serves as a synthetic intermediate for LO-4-25. LO-4-25 is a ligand for the androgen receptor (AR) DNA binding domain and is linked to a truncated fumaramide handle via a connector. In 22Rv1 cells, LO-4-25 demonstrates potent degradation of both AR and AR-V7.</p>Couleur et forme :Odour Solid9,10-Dihydrophenanthrene
CAS :<p>9,10-Dihydrophenanthrene has inhibitory activity against the androgen receptor and can be used in related research in the field of life sciences.</p>Formule :C14H12Degré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :180.25Eprosartan
CAS :<p>Eprosartan is a selective AT1 receptor blocker with IC50s of 9.2 nM (rat) and 3.9 nM (human), used for hypertension.</p>Formule :C23H24N2O4SDegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :424.51Estrogen receptor modulator 6
CAS :<p>ER modulator 6 (3a) is a potent ERβ agonist with a K i of 0.44 nM; 19x more selective for ERβ than ERα.</p>Formule :C18H16F2O3Couleur et forme :SolidMasse moléculaire :318.32OBHSA
CAS :<p>OBHSA（Oxabicycloheptane sulfonamide） is a novel selective estrogen receptor depressant (SERD) that can be used to study breast cancer.</p>Formule :C27H24F3NO6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :547.54Potassium Channel Targeted Library
<p>A unique collection of xnum potassium channel blockers and agonists for high throughput and high content screening;</p>Couleur et forme :Odour SolidST-CY14
<p>ST-CY14 is an inhibitor of the Nur77-PPARγ interaction with an EC50 of 3.15 μM. It binds to Nur77 (Kd=32 nM) to prevent its ubiquitination and degradation by PPARγ, reducing fatty acid uptake and mitochondrial respiration, and inhibiting the transcription of CD36 and FABP4. ST-CY14 suppresses proliferation and migration of MCF7 and MDA-MB-231 cancer cells and impedes tumor growth and bone metastasis in mouse models.</p>Formule :C139H237N57O31S2Couleur et forme :SolidMasse moléculaire :3266.86Angiotensin II 5-valine
CAS :<p>ngiotensin II 5-valine is an angiotensin II analog which is an agonist at angiotensin receptors.</p>Formule :C49H69N13O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :N/AHistamine & Melatonin Receptor-Targeted Compound Library
<p>A unique collection of xnum compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS</p>Couleur et forme :Odour SolidPTP1B/AKR1B1-IN-2
<p>PTP1B/AKR1B1-IN-2 (Compound 7f) is a potent inhibitor targeting both PTP1B and AKR1B1 with IC50 values of 3.2 and 2.1 μM, respectively, and K i values of 4.0</p>Formule :C23H23NO4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :441.56Ro 64-6198
CAS :<p>Ro 64-6198: Nonpeptide, selective NOP agonist, high brain uptake, EC50=25.6 nM, 100x NOP>opioid affinity.</p>Formule :C26H31N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :401.54AKR1C3-IN-10
<p>AKR1C3-IN-10 (compound 5r), a selective inhibitor of AKR1C3 with an IC50 of 51 nM, demonstrates efficacy in a prostate cancer xenograft model [1].</p>Formule :C24H20N4O3Couleur et forme :SolidMasse moléculaire :412.44Azilsartan Medoxomil Potassium
CAS :<p>Azilsartan Medoxomil Potassium (TAK-491 Potassium) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.</p>Formule :C30H23N4O8·KDegré de pureté :98.72%Couleur et forme :SolidMasse moléculaire :606.62AZ 1729
CAS :<p>FFA2 modulator; inhibits cAMP, enhances 35SGTPγS binding (pEC50: 6.9, 7.23); alters Gi/Gq signaling; affects lipolysis, neutrophil migration.</p>Formule :C18H16FN5OSCouleur et forme :SolidMasse moléculaire :369.42Hydrocortisone sodium succinate
CAS :<p>Hydrocortisone sodium succinate is a glucocorticoid which is used to alleviate allergic reactions, particularly those of the skin and gums.</p>Formule :C25H34NaO8Couleur et forme :SolidMasse moléculaire :485.529Antihypertensive agent 2
<p>Antihypertensive agent 2 (Compound 4g) exhibits effective antagonistic activities against angiotensin II receptor 1 and reduces blood pressure with equal or</p>Formule :C22H15NO3Couleur et forme :SolidMasse moléculaire :341.36β-Endorphin, equine
CAS :<p>Endorphin Beta is A substance produced in the brain, especially in the pituitary gland, Endorphin Beta blocks the sensation of pain.</p>Formule :C154H248N42O44SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :3423.94L 363564
CAS :<p>L 363564 is a kidney renin inhibitor.</p>Formule :C54H76N12O10Couleur et forme :SolidMasse moléculaire :1053.276ERRγ agonist-2
CAS :<p>ERRγ agonist-2 is a potent and selective ERRγ inverse agonist with a K d value of 6.5 μM.</p>Formule :C27H21N5O2Couleur et forme :SolidMasse moléculaire :447.49Imidaprilate
CAS :<p>Imidaprilate, an active TA-6366 metabolite, is a potent ACE inhibitor with an IC50 of 2.6 nM, researched for hypertension.</p>Formule :C18H23N3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :377.39PROTAC ER Degrader-14
CAS :<p>PROTAC ER Degrader-14 (compound 86) is a PROTAC-type estrogen receptor/ERR degrader. It comprises an E3 ubiquitin ligase ligand (blue part) (S)-Deoxy-thalidomide, a PROTAC linker (black part) N-Boc-piperazine, and a target protein ligand (red part) ER ligand-6. The combination of the E3 ligase and linker forms tert-Butyl (S)-4-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)piperazine-1-carboxylate.</p>Formule :C44H46FN5O5Couleur et forme :SolidMasse moléculaire :743.865T4-ATA (S-isomer)
<p>T4-ATA S-isomer, the active form of the thyroid hormone, represents the S-isomer of T4-ATA.</p>Formule :C19H15I4NO6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :893.01ERD-308
CAS :<p>ERD-308, potent at 5nM, achieves >95% ER degradation in ER+ breast cancer, with DC50 of 0.17-0.43 nM.</p>Formule :C55H65N5O9S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1004.26U-54494A hydrochloride
CAS :<p>U-54494A hydrochloride is a benzamide derivative related to kappa opioid receptor agonists. U-54494A hydrochloride has anticonvulsant activity.</p>Formule :C18H25Cl3N2OCouleur et forme :SolidMasse moléculaire :391.76Ocedurenone
CAS :<p>Ocedurenone, a corticosteroid receptor antagonist, is a compound utilized in the investigation of kidney disease (WO2018054357, compound I).</p>Formule :C28H30ClN5O2Couleur et forme :SolidMasse moléculaire :504.03AKR1B10-IN-1
CAS :<p>AKR1B10-IN-1: potent AKR1B10 inhibitor, IC50 3.5 nM; hinders lung cancer cell growth, spread, and Cisplatin resistance.</p>Formule :C19H16FNO4Couleur et forme :SolidMasse moléculaire :341.338PROTAC ERα Degrader-2
CAS :<p>PROTAC ERα Degrader-2 is composed of a cIAP1 ligand binding group, a linker, and an estrogen receptor α (ERα) binding group, serving as an ERα degrader.</p>Formule :C42H61N5O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :763.96Dagrocorat hydrochloride
CAS :<p>PF-0251802 HCl is a bio-active chemical.</p>Formule :C29H30ClF3N2O2Couleur et forme :SolidMasse moléculaire :531.012-sec-Butylphenol
CAS :<p>2-sec-Butylphenol is an inhibitor of the androgen receptor and P450 aromatase, and can be used in research and experiments in the field of life sciences.</p>Formule :C10H14OCouleur et forme :SolidMasse moléculaire :150.22Urotensin II (114-124), human
CAS :<p>Human Urotensin II (114-124) is an 11-amino acid peptide with vasoconstrictor properties and agonizes GPR14.</p>Formule :C64H85N13O18S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1388.57Antihypertensive agent 3
<p>Antihypertensive agent 3 (compound 4a), an angiotensin II receptor 1 antagonist, demonstrates antihypertensive activity in spontaneously hypertensive rats (SHRs</p>Formule :C16H13NO4SCouleur et forme :SolidMasse moléculaire :315.34Dynorphin B (1-13)
CAS :Dynorphin B (1-13) acts as an agonist on opioid κ-receptor.Formule :C74H115N21O17Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1570.84PROTAC ER Degrader-2
<p>PAC, based on WO2017201449A1's LP2, enhances ERα degradation; used in making ADCs with PROTAC-linker, it's attached to antibodies.</p>Formule :C89H104N12O15Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1581.85(Glu2)-TRH
CAS :(Glu2)-TRH: Stable TRH analog; reduces TRH's cholinergic action; no thyroliberinase metabolism; neuroprotective with antidepressant, anticonvulsant effects.Formule :C15H22N4O6Couleur et forme :SolidMasse moléculaire :354.36[Arg8]-Vasotocin
CAS :<p>[Arg8]-Vasotocin is a hormone present in the neurohypophysis of nonmammalian vertebrates that is related to vasopressin and oxytocin.</p>Formule :C43H67N15O12S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1050.22N-Acetyl-α-Endorphin
CAS :N-Acetyl-α-Endorphin is a chemical compound consisting of α-Endorphin that has been acetylated at the N-terminal.Formule :C79H122N18O27SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1787.98Dynorphin A (1-8)
CAS :<p>Dynorphin (1-8) is an opioid octapeptide from the porcine hypothalamus. It comprises the N-terminal eight residues of dynorphin.</p>Formule :C46H72N14O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :981.15[Ala17]-MCH TFA
<p>'[Ala17]-MCH TFA is an MCH analogue, a selective MCHR1 ligand (Ki=0.16 nM) with high affinity (Kd=0.37 nM), and low MCHR2 affinity (Ki=34 nM).</p>Formule :C99H156F3N29O28S4Couleur et forme :SolidMasse moléculaire :2385.73MCH(human, mouse, rat) TFA
<p>MCH TFA, a peptide, selectively binds MCH1R and MCH2R with IC50 of 0.3nM, 1.5nM; EC50s are 3.9nM (MCH1R) and 0.1nM (MCH2R) in CHO cells.</p>Formule :C107H161F3N30O28S4Couleur et forme :SolidMasse moléculaire :2500.86SL910102
CAS :<p>SL910102 is a nonpeptide angiotensin antagonist of the AT1 receptor.</p>Formule :C30H30N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :490.60OT antagonist 1 demethyl derivative
<p>OT antagonist 1 demethyl derivative is the demethyl derivative of OT antagonist 1. OT antagonist 1 is a selective Oxytocin antagonist (Ki of 50 nM. )</p>Formule :C21H20N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :376.411-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone
CAS :<p>1-Methyl-quinolone alkaloid inhibits DAG acyltransferase, blocks angiotensin II receptor (IC50s: 20.1 & 34.1 μM), and fights H. pylori (MIC: 10 μg/mL).</p>Formule :C23H31NOCouleur et forme :SolidMasse moléculaire :337.5PROTAC ER Degrader-15
<p>PROTAC ER Degrader-15 (Compound 40) is an orally active estrogen receptor (ER) degrader with anticancer properties, suitable for breast cancer research.</p>Formule :C47H47F4N5O5Couleur et forme :SolidMasse moléculaire :837.9SR 43845
CAS :<p>SR 43845 is an inhibitor of renin.</p>Formule :C44H64N8O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :833.044Floramanoside C
CAS :<p>Floramanoside C exhibits 2,2-diphenyl-1-picrylhydrazyl scavenging and aldose reductase inhibitory activities [1].</p>Formule :C21H18O15Couleur et forme :SolidMasse moléculaire :510.36CTOP
CAS :<p>Potent μ-receptor antagonist, Ki=0.96nM, ineffective at δ (>10,000nM). Alters behavior in vivo, boosts K+ currents in rat neurons in vitro, μ-independent.</p>Formule :C50H67N11O11S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1062.28Abaloparatide
CAS :<p>Abaloparatide (BA 058) is a selective PTHR1 analog that promotes bone growth and may be researched for osteoporosis.</p>Formule :C174H300N56O49Couleur et forme :SolidMasse moléculaire :3960.59Locicortolone
CAS :<p>Locicortolone is a synthetic glucocorticoid corticosteroid which was never marketed.</p>Formule :C22H28Cl2O3Couleur et forme :SolidMasse moléculaire :411.36Aclerastide
CAS :<p>Aclerastide, an angiotensin receptor agonist, decreases fibrosis in wounds; effect increases with use duration, blocked by AT antagonist.</p>Formule :C42H64N12O11Couleur et forme :SolidMasse moléculaire :913.03Linuron
CAS :<p>Linuron herbicide disrupts photosynthesis and acts as an androgen receptor antagonist.</p>Formule :C9H10Cl2N2O2Degré de pureté :99.08%Couleur et forme :White Crystalline Solid Linuron Is A Colorless Crystals Non Corrosive Used As An HerbicideMasse moléculaire :249.09Prednicarbate
CAS :<p>Prednicarbate (Hoe 777), a corticosteroid, has antipruritic, anti-inflammatory effects, reduces lymphocytes, and inhibits vasodilators.</p>Formule :C27H36O8Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :488.57Ditekiren
CAS :<p>Ditekiren is a renin inhibitor with orally active.</p>Formule :C50H75N9O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :930.19OP-3633
CAS :<p>OP-3633: potent GR antagonist (IC50: 29 nM), low PR agonism, AR antagonism, inhibits GR transcription.</p>Formule :C30H39NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :445.64RTI-13951-33 hydrochloride
<p>RTI-13951-33 HCl: potent, selective GPR88 agonist; brain-penetrant; EC50 = 25nM; curbs rat alcohol behaviors.</p>Formule :C28H35Cl2N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :532.5GLL 398
CAS :<p>GLL 398 is an orally active and selective degrader of estrogen receptor with an IC50 of 1.14 nM. GLL 398 blocks tumor growth in xenograft breast cancer models.</p>Formule :C25H23BO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :398.26Hemorphin-7
CAS :<p>Hemorphin-7, an atypical opioid peptide from hemoglobin, may enhance memory, promote cell growth, and is a potential breast cancer biomarker.</p>Formule :C49H64N12O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :997.11TAN67
CAS :<p>TAN67 is the first effective selective non-peptide delta1 opioid receptor.</p>Formule :C23H26Br2N2OCouleur et forme :SolidMasse moléculaire :506.282Handle region peptide, rat
CAS :<p>Rat handle region peptide acts as prorenin receptor blocker, curbs diabetic kidney disease, and reduces eye inflammation.</p>Formule :C54H101N15O12SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1184.547β-Hydroxy-epi-androsterone
CAS :<p>7β-Hydroxy-epi-androsterone (7β-Hydroxy-EpiA) is an endogenous androgenic derivative of dehydroepiandrosterone that possesses the ability to bind to ERβ,</p>Formule :C19H30O3Couleur et forme :SolidMasse moléculaire :306.44Lactandrate
CAS :<p>Lactandrate is a homo-aza-steroidal ester of p-bis(2-chloroethyl) amino phenyl acetic acid.</p>Formule :C31H44Cl2N2O3Couleur et forme :SolidMasse moléculaire :563.6BAM-22P
CAS :<p>Bovine adrenal medulla docosapeptide (BAM-22P) is a potent opioid agonist, derived from the proenkephalin A gene, which is present in the adrenal medulla.</p>Formule :C130H184N38O31S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2839.2211-Ketodihydrotestosterone
CAS :<p>11-Ketodihydrotestosterone is a metabolite of 11β-Hydroxyandrostenedione. It is an active androgen and is also a potent androgen receptor (AR) agonist (Ki: 20.4 nM, EC50: 1.35 nM for human AR).</p>Formule :C19H28O3Couleur et forme :SolidMasse moléculaire :304.42Zankiren
CAS :<p>Zankiren is a renin inhibitor. Zankiren can reduce blood pressure, plasma renin activity, and angiotension II.</p>Formule :C35H55N5O6S2Couleur et forme :SolidMasse moléculaire :705.97D3R/MOR antagonist 1
<p>Compound 114 (D3R/MOR antagonist 1) exhibits dual antagonistic activity at dopamine D3 receptors (D3R) and mu-opioid receptors (MOR), with K i values of 46.5 nM</p>Formule :C22H27Cl2N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :420.38PROTAC ERα Degrader-8
CAS :<p>PROTAC ERα Degrader-8 (compound ii-56), a highly potent degrader of Erα, achieves a DC50 of just 0.000006 μM in MCF7 cells [1].</p>Formule :C47H51N5O4Couleur et forme :SolidMasse moléculaire :749.94ICI 174,864
CAS :<p>Selective δ opioid antagonist. Exhibits partial agonist in vitro activity at δ receptors at high concentrations.</p>Formule :C38H53N5O7Degré de pureté :98%Couleur et forme :White SolidMasse moléculaire :691.87KOR agonist 4
<p>KOR agonist 4 (compound 39) is an agonist targeting the κ opioid receptor (Kappa Opioid Receptor) and activates G protein signaling. It has an EC50 of 14 nM and an Emax of 83% for binding to GTPγS. This compound demonstrates moderate to high intrinsic clearance in human liver cells and shows selectivity for the κ opioid receptor over the μ (MOR) and δ (DOR) opioid receptors by factors of 60 and 810, respectively. KOR agonist 4 is useful for research into central nervous system (CNS) disorders.</p>Formule :C21H25N3Couleur et forme :SolidMasse moléculaire :319.44Vasopressin Dimer (anti-parallel) (TFA)
<p>Vasopressin Dimer (anti-parallel) TFA, an anti-parallel dimer form of vasopressin, has the capability to activate four G protein-coupled receptors: V1aR, V1bR,</p>Formule :C94H131F3N30O26S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2282.49Nociceptin(1-7)
CAS :<p>Bioactive metabolite of nociceptin, antagonist of nociceptin-induced hyperalgesia</p>Formule :C31H41N7O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :655.709MT-7716 free base
CAS :<p>MT-7716: selective NOP agonist, potential in preventing alcohol abuse/relapse.</p>Formule :C27H28N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :440.54Raloxifene 4'-glucuronide
CAS :<p>Raloxifene 4'-glucuronide is a primary metabolite of Raloxifene.</p>Formule :C34H35NO10SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :649.714A7C-301
<p>4A7C-301, a Nurr1 agonist, exhibits potent neuroprotective effects in vitro and markedly mitigates neuropathological abnormalities while enhancing motor and</p>Couleur et forme :Odour Solid[Nphe1]Nociceptin(1-13)NH2 TFA
<p>[Nphe1]Nociceptin(1-13)NH2 is a selective nociceptin receptor antagonist with potential analgesic properties, pKi=8.4, pA2=6.0.</p>Formule :C63H101F3N22O17Couleur et forme :SolidMasse moléculaire :1495.61CJ-15208
CAS :<p>CJ-15208: κ-opioid antagonist, IC50: 47 nM kappa, 260 nM mu, 2600 nM delta, reverses asimadoline effects in rabbits (ED50 1.3 µM).</p>Formule :C34H35N5O4Couleur et forme :SolidMasse moléculaire :577.67Orphanin FQ(1-11)
CAS :<p>Nociceptin peptide fragment (1-11) with potent ORL1/KOR-3 receptor agonism (Ki = 55 nM), no opioid receptor affinity, and analgesic in mice.</p>Formule :C49H75N15O14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1098.2SNIPER(ER)-87
CAS :<p>SNIPER(ER)-87 is a chemical compound composed of a derivative of the inhibitor of apoptosis protein (IAP) ligand LCL161 conjugated to the estrogen receptor α (</p>Formule :C59H73N5O10SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1044.32Triphenylethylene
CAS :<p>Compound PDK0283, with CAS No. 58-72-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0283 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formule :C20H16Couleur et forme :White PowderMasse moléculaire :256.34Angiotensin II (1-4), human TFA
<p>Angiotensin II is a potent direct vasoconstrictor, causing arteries and veins to constrict, so leading to an increase in blood pressure.</p>Formule :C26H38F3N7O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :665.62KOR agonist 5
<p>KOR agonist 5 (Compound 10a) is both a KOR/MOR modulator, exhibiting agonistic effects on KOR and antagonistic effects on MOR. It effectively blocks morphine-induced antinociception and gastrointestinal motility inhibition. KOR agonist 5 is applicable in research related to substance use disorder (SUD).</p>Formule :C38H38N2O5Couleur et forme :SolidMasse moléculaire :602.72Inocoterone acetate
CAS :<p>Inocoterone acetate is a nonsteroidal antiandrogen that binds to the androgen receptor and possesses antiandrogenic activity in animal models.</p>Formule :C18H26O3Couleur et forme :SolidMasse moléculaire :290.40RS 21314
CAS :<p>RS 21314 is a thiol ester corticosteroid that is topical.</p>Formule :C24H30F2O5SCouleur et forme :SolidMasse moléculaire :468.5518-Oxocortisol
CAS :<p>18-Oxocortisol, a naturally occurring mineralocorticoid and adrenal biomarker, is produced by CYP11B2.</p>Formule :C21H28O6Couleur et forme :SolidMasse moléculaire :376.449
![1-Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT38593.webp&w=3840&q=75)
![[Met5]-Enkephalin, amide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP1255.webp&w=3840&q=75)
![[Arg14,Lys15]Nociceptin](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP1986.webp&w=3840&q=75)
![[Sar1, Ile8]-Angiotensin II](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT7575.webp&w=3840&q=75)
![[Arg8]-Vasotocin](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP1400.webp&w=3840&q=75)
![1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT75697.webp&w=3840&q=75)
