Endocrinologie/Hormones
Les inhibiteurs en endocrinologie/hormonaux sont des composés qui bloquent l'action des hormones ou interfèrent avec les voies de signalisation hormonales. Ces inhibiteurs sont essentiels pour étudier la régulation des systèmes endocriniens et pour développer des traitements pour les maladies liées aux hormones, telles que le diabète, les troubles de la thyroïde et les cancers hormonodépendants. En modulant l'activité hormonale, ces inhibiteurs peuvent aider à élucider les interactions complexes au sein du système endocrinien. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité en endocrinologie/hormonaux pour soutenir vos recherches en endocrinologie, pharmacologie et sciences médicales.
Sous-catégories appartenant à la catégorie "Endocrinologie/Hormones"
- Récepteur des androgènes(229 produits)
- Annexine A(16 produits)
- Aromatase(23 produits)
- Récepteur d'œstrogène/progestatif(66 produits)
- GPR(1 produits)
- Récepteur des glucocorticoïdes(164 produits)
- LHRH(2 produits)
- Récepteur opioïde(327 produits)
- Récepteur de prostaglandine(122 produits)
- RAAS(89 produits)
- Réductase(51 produits)
- Somatostatine(57 produits)
- Récepteur des hormones thyroïdiennes (THR)(34 produits)
- Récepteur de la vasopressine(48 produits)
Affichez 6 plus de sous-catégories
3419 produits trouvés pour "Endocrinologie/Hormones"
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Dimestrol
CAS :Dimestrol can induce DNA damage.Formule :C20H24O2Couleur et forme :SolidMasse moléculaire :296.4Dafphedyn
CAS :Dafphedyn (DAFPHEDYN), a potent endorphin 1-13 analog, induces diuresis and analgesia in rats via IV.Formule :C76H124F5N25O14Couleur et forme :SolidMasse moléculaire :1706.95Oxytocin parallel dimer
CAS :Oxytocin parallel dimer is the disulfide-bridged homo peptide dimer.Formule :C86H132N24O24S4Couleur et forme :SolidMasse moléculaire :2014.39Fluticasone 17β-Carboxylic Acid
CAS :Fluticasone 17β-carboxylic acid is an intermediate in the synthesis of the glucocorticosteroid fluticasone propionate .1Formule :C21H26F2O5Couleur et forme :SolidMasse moléculaire :396.42(-)-Vorozole
CAS :(-)-Vorozole, potent/selective oral non-steroidal aromatase inhibitor, shows antitumor activity, used in breast cancer research.Formule :C16H13ClN6Degré de pureté :99.02% - >99.99%Couleur et forme :SoildMasse moléculaire :324.77(±)-ErSO
CAS :(±)-ErSO is the racemic form of ErSO. ErSO is a selective anticipatory activator of the unfolded protein response (a-UPR).Formule :C22H13F6NO3Couleur et forme :SolidMasse moléculaire :453.3417β-hydroxy Exemestane
CAS :17β-hydroxy Exemestane is the primary active metabolite of exemestane .Formule :C20H26O2Couleur et forme :SolidMasse moléculaire :298.425-methyl-2-HOBA (hydrochloride)
CAS :5-methyl-2-HOBA is an isoketal scavenger. It reduces angiotensin II-induced increases in systolic blood pressure in mice.Formule :C8H12ClNOCouleur et forme :SolidMasse moléculaire :173.64Lodoxamide ethyl
CAS :lodoxamide ethyl is a new orally active anti-allergic compound for the prevention of antigen-induced bronchoconstriction and blockage of skin allergic reactionsFormule :C15H14ClN3O6Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :367.74[Phe1Ψ(CH2-NH)Gly2]Nociceptin(1-13)NH2
CAS :Potent agonist of the nociceptin (ORL1) receptor, demonstrated both in vitro and in vivo.Formule :C61H102N22O14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1367.6ER ligand-6
CAS :ER ligand-6 serves as the target protein ligand for the PROTAC ER Degrader-14.
Formule :C29H32FNO4Couleur et forme :SolidMasse moléculaire :477.567ER ligand-7
ER ligand-7 is a ligand for the estrogen receptor (ER) that can be used as a target protein ligand for synthesizing PROTAC ER Degrader-15.
Formule :C27H23F4NO3Couleur et forme :SolidMasse moléculaire :485.47Tamoxifen-PEG-Clozapine
Tamoxifen-PEG-Clozapine is an estrogen receptor α (ERα) PROTAC degrader. It targets ERα for degradation through the ubiquitin-proteasome system by utilizing the E3 ubiquitin ligase component N-recognin 5. This compound is applicable in cancer research. (Pink: ERα inhibitor; Black: linker; Blue: CRBN Ligand)Formule :C54H63ClN6O7Couleur et forme :SolidMasse moléculaire :943.567AR ligand-33
AR ligand-33 is a ligand for the androgen receptor (AR), and it can be used as a target protein ligand for the synthesis of PROTAC AR Degrader-8.Formule :C25H28N2O3Couleur et forme :SolidMasse moléculaire :404.501RU26988
CAS :RU26988 is a bioactive chemical.Formule :C22H26O3Couleur et forme :SolidMasse moléculaire :338.44Paramethasone
CAS :Parametasone is a glucocorticoid with the general properties of corticosteroids.Formule :C22H29FO5Couleur et forme :SolidMasse moléculaire :392.46Human PTHrP-(1-36)
CAS :Human PTHrP-(1-36) is a secreted form of parathyroid hormone-related protein that exhibits anticalciuric effects and promotes beta cell function andFormule :C191H305N59O52Couleur et forme :SolidMasse moléculaire :4259.83Demoxytocin
CAS :Demoxytocin, oxytocin analog, enhances smooth muscle contraction by increasing calcium ion permeability. Used in labor research.Formule :C43H65N11O12S2Couleur et forme :SolidMasse moléculaire :992.17PROTAC ER Degrader-12
PROTACER Degrader-12 (Compound 70) is an estrogen receptor PROTAC degrader with a degradation concentration (DC50) of less than 10 nM. It inhibits the proliferation of MCF-7 cells at a DC50 of under 10 nM and exhibits anticancer properties.Formule :C47H48F3N5O5Masse moléculaire :819.36075Angiotensin II (3-8), human TFA
Angiotensin II (3-8), human (TFA) is an angiotensin AT1 receptor agonist with less activity.Formule :C42H55F3N8O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :888.93β-S-ARCA triammonium
β-S-ARCA (triammonium) is an analog of the mRNA7-methylguanosine (m7G) cap structure, featuring a thio-phosphorylated segment. When bound to mRNA, β-S-ARCA (triammonium) extends the cellular half-life and enhances protein expression. This compound is utilized in research for mRNA-based cancer vaccines.Formule :C22H40N13O17P3SCouleur et forme :SolidMasse moléculaire :883.62K-Opioid receptor agonist-1
CAS :K-Opioid receptor agonist-1 (Compound 5a) acts as an agonist for the κ-Opioid receptor, exhibiting a K_i of 0.25 nM and an EC_50 of 2 nM. This compound is capable of crossing the blood-brain barrier (BBB), evidenced by brain/plasma ratios ranging from 0.50 to 0.65. Additionally, K-Opioid receptor agonist-1 demonstrates anti-inflammatory effects in dermatitis models induced by either Arachidonic acid or oxazolidinone.Formule :C22H29Cl2N3O3Masse moléculaire :454.39Bilaid C
CAS :Bilaid C: Tetrapeptide μ-opioid agonist from Penicillium (Ki=210 nM), inhibits cAMP (77% at 10 μM), induces Kir currents (EC50=4.2 μM).Formule :C28H38N4O6Masse moléculaire :526.62D-Ala-Gly-Phe-Met-NH2 monoacetate
CAS :D-Ala-Gly-Phe-Met-NH2 monoacetate, an opioid peptide, serves as a potent agonist for the opiate δ-receptor [1].Formule :C21H33N5O6SCouleur et forme :SolidMasse moléculaire :483.58PROTAC AR Degrader-10
PROTACAR Degrader-10 is a protein degrader targeting androgen receptors (AR) with a DC50 value of ≤100 nM, and can be used in prostate cancer research.6-Amino-5-bromoquinoxaline
CAS :Compound PDK0245, with CAS No. 50358-63-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0245 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formule :C8H6BrN3Couleur et forme :Yellow SolidMasse moléculaire :224.05[D-Ala2]-Met-Enkephalinamide
CAS :[D-Ala2]-Met-Enkephalinamide: potent opioid, reduces bile flow centrally, analgesic.Formule :C28H38N6O6SMasse moléculaire :586.7Trh-gly
CAS :TRH-glycine (TRH-gly) serves as a precursor to thyrotropin-releasing hormone (TRH), capable of inducing the release of thyrotropin (TSH) and prolactin [1].Formule :C18H24N6O6Couleur et forme :SolidMasse moléculaire :420.42ACTH (6-24) (human)
CAS :Adrenocorticotropic hormone (6-24) (ACTH (6-24) (human)) is a fragment of ACTH that acts as a competitive inhibitor of steroidogenesis prompted by full-lengthFormule :C111H175N35O21Couleur et forme :SolidMasse moléculaire :2335.8Enkephalin-met, ala(2)-
CAS :Enkephalin-met, ala(2)- is a synthetic analog of methionine enkephalin.Formule :C28H37N5O7SCouleur et forme :SolidMasse moléculaire :587.69Human PTH-(1-31) amide
CAS :Human PTH-(1-31) amide, an analog of PTH, effectively stimulates phosphatidylcholine hydrolysis and promotes the release of adenylyl cyclase [1].Formule :C162H270N50O46S2Couleur et forme :SolidMasse moléculaire :3718.31MOR agonist-4
MOR agonist-4 (2d), having an EC50 of 11 nM, is a G protein-biased agonist of the Kappa opioid receptor (KOR). This compound features a triazole-based, electron-withdrawing CF3 group and a bias factor of 38. MOR agonist-4 is utilized for antipruritic and analgesic applications.Couleur et forme :Odour SolidArg-Glu(edans)-Ile-His-Pro-Phe-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(dabcyl)-Arg
Arg-Glu(edans)-Ile-His-Pro-Phe-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(dabcyl)-Arg is a fluorescent renin substrate based on the N-terminal tetrapeptide sequence of human angiotensinogen (hTDP).Formule :C129H179N37O24SMasse moléculaire :2662.36444Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat)
CAS :Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat), also known as Human PTHrP (107-111) amide, is a C-terminal fragment of parathyroidFormule :C27H42N10O7Masse moléculaire :618.69Kisspeptin-14 human
CAS :Kisspeptin-14 human is an active fragment peptide of Kisspeptin encoded by the KiSS-1 gene. Kisspeptin-14 human is a GPR54 agonist for human and rat.Formule :C82H112N22O21Couleur et forme :SolidMasse moléculaire :1741.9Acetalin-2
CAS :Acetalin-2, an opioid peptide with the sequence Ac-Arg-Phe-Met-Trp-Met-Arg-NH2, selectively binds to [3 H]DAMGO with a Ki value of 93.3 nM [1].Formule :C44H66N14O7S2Masse moléculaire :967.21Antiproliferative agent-51
Antiproliferative agent-51 (Compound 18h) inhibits estrogen receptor α (ERα)-mediated transcription with an IC50 of 1.6 nM. It also suppresses the proliferation of cancer cells ZR-75, with an IC50 of 0.031 μM, and exhibits antitumor activity in mouse models.Formule :C43H50N4O9Masse moléculaire :766.35778Chymase
CAS :Chymase is a proteolytic enzyme predominantly found in mast cells (MC), fibroblasts, and vascular endothelial cells. It is released into the extracellular matrix in response to inflammatory signals, tissue damage, and cellular stress. Chymase also plays a role in the generation of angiotensin II (Ang II), making it significant for cardiovascular disease research.Termitomycamide B
CAS :Termitomycamide B, a fatty acid from T. titanicus, protects Neuro2a cells from ER stress-induced death at 0.1 μg/ml.Formule :C28H40N2O2Couleur et forme :SolidMasse moléculaire :436.63β-Chlornaltrexamine dihydrochloride
CAS :β-Chlornaltrexamine dihydrochloride (β-CNA dihydrochloride) is an effective long-term antagonist of opioid receptors. It efficiently blocks the inhibition of dopamine release mediated by κ opioid receptor agonists. This compound is useful in the research of pain perception mechanisms.Formule :C24H34Cl4N2O3Couleur et forme :SolidMasse moléculaire :540.35Ota-vasotocin
CAS :Ota-vasotocin is a ligand utilized in quantitative receptor autoradiography for oxytocin receptors.Formule :C54H79N11O13S2Masse moléculaire :1154.41TRV055
CAS :TRV055: Gq-biased AT1R ligand, stimulates Gq signaling, aids Gq-biased agonist development.Formule :C42H57N9O9Couleur et forme :SolidMasse moléculaire :831.972[Asp5]-Oxytocin
CAS :[Asp5]-Oxytocin is the first 5-position neurohypophyseal hormone analogue possessing significant biological activity.Formule :C43H65N11O13S2Masse moléculaire :1008.18Morphiceptin
CAS :Morphiceptin is a synthetic tetrapeptide with morphinelike activities, highly specific for morphine receptors, but not for enkephalin receptors.Formule :C28H35N5O5Masse moléculaire :521.61Detrothyronine
CAS :Detrothyronine is a biochemical.Formule :C15H12I3NO4Couleur et forme :SolidMasse moléculaire :650.97Biotin-Oxytocin
Biotin-Oxytocin (Biotin-α-Hypophamine; Biotin-Oxytocic hormone) is a biologically active peptide. It is oxytocin labeled with biotin at the N-terminus.Formule :C53H80N14O14S3Masse moléculaire :1232.51406[Asp5]-Oxytocin acetate
[Asp5]-Oxytocin acetate: a biologically active neurohypophyseal hormone analogue, inducing uterine contractions, effects magnified by Mg2+.Formule :C45H69N11O15S2Masse moléculaire :1068.22BPRMU191
CAS :BPRMU191 is a distinct mu-opioid receptor (MOR) modulator with an EC50 of 2.17 μM in FLIPR Ca2+ assays conducted on CHO-K1/MOR/Gα15 cells. Additionally, BPRMU191 interacts with MOR in the presence of naloxone.Formule :C17H14FNO3SCouleur et forme :SolidMasse moléculaire :331.36Saprisartan
CAS :Saprisartan (GR-138950, GR-138950X) is an AT1 receptor antagonist used for the treatment of heart failure and blood pressure.Formule :C25H22BrF3N4O4SCouleur et forme :SolidMasse moléculaire :611.43Keap1-IN-1
Keap1-IN-1 (Compound 27) is an inhibitor of Keap1, functioning by covalently modifying the Cys151 residue on the BTB domain of KEAP1, thereby disrupting the interaction between Keap and Nrf. It enhances the mRNA expression of the antioxidant response element (ARE) dependent gene NQO1, with an EC50 of 160 nM, and exhibits cytotoxicity in U2OS cells, with an EC50 of 527 nM.Formule :C17H21Cl2N2O5PS3Couleur et forme :SolidMasse moléculaire :531.434
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