Endocrinologie/Hormones
Les inhibiteurs en endocrinologie/hormonaux sont des composés qui bloquent l'action des hormones ou interfèrent avec les voies de signalisation hormonales. Ces inhibiteurs sont essentiels pour étudier la régulation des systèmes endocriniens et pour développer des traitements pour les maladies liées aux hormones, telles que le diabète, les troubles de la thyroïde et les cancers hormonodépendants. En modulant l'activité hormonale, ces inhibiteurs peuvent aider à élucider les interactions complexes au sein du système endocrinien. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité en endocrinologie/hormonaux pour soutenir vos recherches en endocrinologie, pharmacologie et sciences médicales.
Sous-catégories appartenant à la catégorie "Endocrinologie/Hormones"
- Récepteur des androgènes(229 produits)
- Annexine A(16 produits)
- Aromatase(23 produits)
- Récepteur d'œstrogène/progestatif(66 produits)
- GPR(1 produits)
- Récepteur des glucocorticoïdes(165 produits)
- LHRH(2 produits)
- Récepteur opioïde(327 produits)
- Récepteur de prostaglandine(122 produits)
- RAAS(89 produits)
- Réductase(51 produits)
- Somatostatine(57 produits)
- Récepteur des hormones thyroïdiennes (THR)(33 produits)
- Récepteur de la vasopressine(48 produits)
Affichez 6 plus de sous-catégories
3420 produits trouvés pour "Endocrinologie/Hormones"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
Leumorphin, human
CAS :Leumorphin, human, is a potent agonist of the kappa opioid receptor (κ opioid receptor) and inhibits the contraction of the guinea pig ileum's myenteric plexus-Formule :C150H224N42O46Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3351.64AH 7563
CAS :AH 7563 is structurally classified as an opioid compound with analgesic properties. In mice, its ED50 for pain relief was 15.3 mg/kg when administered orally in the Phenylquinone test, and 15.5 mg/kg when injected subcutaneously in the Hot plate test.Formule :C16H24N2OCouleur et forme :SolidMasse moléculaire :260.38U-48520
CAS :U-48520 is an agonist of the μ-opioid receptor (μ-opioid receptor) with an EC50 of 1561 nM.Formule :C16H23ClN2OCouleur et forme :SolidMasse moléculaire :294.82(-)-9-Hydroxycorynantheidine
CAS :(-)-9-Hydroxycorynantheidine (9-O-Desmethyl mitragynine) is a demethylated analog of Mitragynine, functioning as a selective and partial agonist for the μ-opioid receptor (μ-opioid receptor). This compound inhibits electrically stimulated twitch contractions in the guinea pig ileum.Formule :C22H28N2O4Couleur et forme :SolidMasse moléculaire :384.47MOR agonist-2
Compound 46, designated as MOR agonist-2, serves as a D3R antagonist and a MOR agonist with respective K i values of 7.26 nM and 564 nM.Formule :C37H47Cl2N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :680.71WAY-298630
CAS :Fluorophenoxy benzimidazole, a CRTH2 blocker, IC50 < 10 μM for rhinitis, COPD, arthritis, eczema, conjunctivitis.Formule :C17H15FN2O3SDegré de pureté :97.84%Couleur et forme :SolidMasse moléculaire :346.38Pro8-Oxytocin TFA
Pro8-Oxytocin TFA, a modified oxytocin (OXT) ligand, exhibits greater potency and efficacy than the standard mammalian OXT ligand, Leu8-Oxytocin, at primateFormule :C42H62N12O12S2·xC2HF3O2Degré de pureté :98%Couleur et forme :SolidFluorphine
CAS :Fluorphine, an analog of Brorphine, binds to the μ-opioid receptor (MOR) with a Ki of 12.5 nM. It exhibits GTPγS binding activity with an EC50 of 75 nM and β-arrestin 2 recruitment activity with an EC50 of 377 nM, and it also has respiratory depressive effects.Formule :C20H22FN3OCouleur et forme :SolidMasse moléculaire :339.41Orphine
CAS :Orphine is an opioid compound that can amplify the antinociceptive effects reduced by naloxone in mice.Formule :C20H23N3OCouleur et forme :SolidMasse moléculaire :321.42PF-06478939 TFA
PF-06478939 TFA is a peptide that acts as a non-brain-penetrating agonist at the oxytocin (OT) and vasopressin receptors, exhibiting EC50 values of 0.01 nM andFormule :C78H134N14O22S2·xC2HF3O2Degré de pureté :98%Couleur et forme :Solid(Val3,Pro8)-Oxytocin
CAS :(Val3,Pro8)-Oxytocin functions primarily as a Gq-dependent pathway agonist and exhibits secondary activity as a reduced efficacy agonist for β-arrestinFormule :C41H60N12O12S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :977.12CSD-CH2(1,8)-NH2
CSD-CH2(1,8)-NH2 is a selective and competitive kappa-opioid receptor (KOR) antagonist with a K i of 6.8 nM.Formule :C76H125N25O15S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1693.09DALDA TFA
DALDA TFA is a potent, μ-opioid receptor agonist exhibiting high selectivity and an affinity constant (K i) of 1.69 nM.Formule :C30H45N9O5·xC2HF3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :611.74 (free base)AH 8529
CAS :AH 8529 is an orally active opioid compound with analgesic properties.Formule :C16H23ClN2OCouleur et forme :SolidMasse moléculaire :294.82N-Phenethylnoroxymorphone
CAS :N-Phenethylnoroxymorphone is an opioid compound that can enhance morphine-induced analgesia in rats. It is used in the research of neurological disorders.Formule :C24H25NO4Couleur et forme :SolidMasse moléculaire :391.46KOR agonist 3
KOR agonist 3 (Compound 5) is an agonist of the κ opioid receptor (κOR) with an EC50 of 0.88 nM. It also exhibits some activation of μOR, with an EC50 of 720 nM. However, KOR agonist 3 does not activate δOR at concentrations below 1 μM. Its ability to recruit β-Arrestin-2 is lower than that of U50488.Formule :C24H24N2O3Couleur et forme :SolidMasse moléculaire :388.46Pro8-Oxytocin
CAS :Pro8-Oxytocin, a modified oxytocin (OXT) ligand, elicits more potent and efficacious responses at primate OXTR and induces stronger behavioral effects comparedFormule :C42H62N12O12S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :991.14Corynantheidine
CAS :Corynantheidine ((-)-Corynantheidine) is a partial agonist of the mu opioid receptor (MOR) and demonstrates MOR-dependent analgesic effects in mice.Formule :C22H28N2O3Couleur et forme :SolidMasse moléculaire :368.47AH 7959
CAS :AH 7959 is an orally active N-substituted cyclohexylmethylbenzamide compound that exhibits analgesic properties. In mice, the ED50 for oral and subcutaneous administration of AH 7959 exceeds 100 mg/kg.Formule :C19H26Cl2N2OCouleur et forme :SolidMasse moléculaire :369.33Dynorphin B (1-9)
CAS :Dynorphin B (1-9), a neuropeptide and the N-terminal cleavage product of dynorphin B, has its formation inhibited by N-ethylmaleimide (NEM), a non-selectiveFormule :C54H78N16O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1143.3AP-238
CAS :AP-238 is a novel synthetic opioid (NSO) that acts as an agonist for the μ-opioid receptor (MOR), with an EC50 of 248 nM. Additionally, AP-238 exhibits analgesic properties.Formule :C18H26N2OCouleur et forme :SolidMasse moléculaire :286.414-Hydroxy-1-(2-phenylethyl)piperidine
CAS :4-Hydroxy-1-(2-phenylethyl)piperidine is a synthetic ligand for muscarinic acetylcholine receptors (mAChR) or non-opioid intracellular sigma-1 receptors (σ1 receptors). It serves as a metabolite of the opioid compounds furanylfentanyl and 4-fluoroisobutyryl fentanyl (FIBF).Formule :C13H19NOCouleur et forme :SolidMasse moléculaire :205.3β-Endorphin (1-27) (human)
CAS :β-Endorphin (1-27) (human) is an opioid antagonist that selectively binds to μ-, δ-, and κ-opioid receptors, with dissociation constants (Kis) of 5.31, 6.17,Formule :C139H217N33O40SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :3022.47PF-06655075 TFA
PF-06655075 (TFA) is the trifluoroacetic acid (TFA) salt of PF-06655075, a novel, non-brain-penetrant oxytocin receptor agonist that exhibits enhancedDegré de pureté :98%Couleur et forme :Odour Solid(1S,2R)-2-PCCA
(1S,2R)-2-PCCA is a novel and potent small molecule GPR88 receptor agonist with an EC50 value of 3 nM in the non-cellular system and 603 nM in the cellularFormule :C30H39Cl2N3ODegré de pureté :99.91%Couleur et forme :SoildMasse moléculaire :528.56Piperidylthiambutene hydrochloride
CAS :Piperidylthiambutene hydrochloride is an opioid compound that exhibits analgesic effects in animal models.Formule :C17H22ClNS2Couleur et forme :SolidMasse moléculaire :339.95DBPR116
CAS :DBPR116 is a prodrug of BPRMU191 that can penetrate the blood-brain barrier. It significantly enhances the delivery efficiency of drugs targeting the central nervous system. When combined with the antagonist Naltrexone, DBPR116 demonstrates superior safety and analgesic effects compared to morphine in various in vivo pharmacological studies, including thermal pain models, cancer pain models, constipation, sedation, psychological dependence, heart rate, and respiratory frequency. As a strategy for peripheral administration, DBPR116 effectively alleviates pain while reducing adverse effects, showing promise as a safer opioid analgesic.Formule :C19H18FNO3SCouleur et forme :SolidMasse moléculaire :359.42PU-WS13 hydrobromide
PU-WS13 hydrobromide is a GRP94 inhibitor with anti-inflammatory activity and inhibits the proliferation of M2-like macrophages in mouse TNBC tumors.Formule :C17H21BrCl2N6SDegré de pureté :99.99%Couleur et forme :SoildMasse moléculaire :492.26R-6890
CAS :R-6890 is an opioid compound with analgesic properties.Formule :C21H24ClN3OCouleur et forme :SolidMasse moléculaire :369.89AH 8532
CAS :AH 8532 is an opioid compound with analgesic effects and is effective in inhibiting the quinone-induced writhing response in mice, with an oral ED50 of 16 mg/kg.Formule :C16H23ClN2OCouleur et forme :SolidMasse moléculaire :294.82PF-06478939
PF-06478939 is a peptide that functions as an agonist at the oxytocin (OT) receptor and vasopressin receptor without crossing the blood-brain barrier.Formule :C78H134N14O22S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1684.11[DPro10] Dynorphin A (1-11)acetate,porcine
[DPro10] Dynorphin A (1-11)acetate,porcine is a highly potent κ-opioid receptor agonist with a Ki value of 0.13 nM.Formule :C65H107N21O15Degré de pureté :99.59%Couleur et forme :SoildMasse moléculaire :1422.7PF-06655075
PF-06655075 is a novel, non-brain-penetrant oxytocin receptor agonist that demonstrates enhanced selectivity for the oxytocin receptor and substantially
Formule :C75H130N14O22S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1644.05Bazedoxifene hydrochloride
CAS :Bazedoxifene hydrochloride (TSE 424 hydrochloride) is an estrogen receptor modulator and an inhibitor of IL-6/GP130 protein interaction.Formule :C30H35ClN2O3Degré de pureté :98.74%Couleur et forme :SolidMasse moléculaire :507.06Ref: TM-T6404
1mg60,00€5mg138,00€10mg240,00€1mL*10mM (DMSO)240,00€25mg374,00€50mg673,00€100mg938,00€500mg1.872,00€Camizestrant TFA
Camizestrant TFA (AZD-9833 TFA) is a potent and orally active antagonist of estrogen receptor (ER).Formule :C26H29F7N6O2Degré de pureté :99.85%Couleur et forme :SoildMasse moléculaire :590.54Ref: TM-T11237L
1mg65,00€5mg150,00€1mL*10mM (DMSO)158,00€10mg215,00€25mg338,00€50mg452,00€100mg662,00€200mg948,00€Valsartan Methyl Ester
CAS :Valsartan Methyl Ester is a potent angiotensin II receptor antagonist, IC50= 0.06uM.
Formule :C25H31N5O3Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :449.55ER ligand-2
ER ligand-2 is a ligand for ER. It can be used in the synthesis of PROTAC ER Degrader-11.Formule :C20H23BrOCouleur et forme :SolidMasse moléculaire :359.3PROTAC ER Degrader-11
CAS :PROTA CER Degrader-11 (Example 26-1) is an effective degrader of PROTA CER with an IC50 of 0.66 nM. It plays a crucial role in cancer research.Formule :C43H53N5O4Couleur et forme :SolidMasse moléculaire :703.914'-Hydroxytamoxifen TFA
4'-Hydroxytamoxifen TFA, a salt form of a metabolite of Tamoxifen, demonstrates higher affinity for ER compared to Tamoxifen itself. This compound induces non-apoptotic cytotoxicity in human endometrial adenocarcinoma cells.Formule :C28H30F3NO4Couleur et forme :SolidMasse moléculaire :501.54ERD-1233
ERD-1233 is an effective oral PROTAC degrader of the estrogen receptor (estrogen receptor) with a DC50 of 0.9 nM. It plays a crucial role in research involving ER+ breast cancer.Formule :C49H53N5O6Couleur et forme :SolidMasse moléculaire :807.986α-Methylprednisolone 21-hemisuccinate sodium salt
CAS :6α-Methylprednisolone 21-hemisuccinate sodium salt (Asmacortone), a water-soluble ester, is used for allergic, cardiac, and hypoxic emergencies.Formule :C26H33NaO8Degré de pureté :99.65%Couleur et forme :Lyophilized PowderMasse moléculaire :496.53Protirelin Acetate
CAS :Protirelin Acetate (TRH Acetate) is a thyrotropin-releasing hormone, stimulating the release of thyrotropin and prolactin from the anterior pituitary.Formule :C16H22N6O4C2H4O2Degré de pureté :96.17%Couleur et forme :SolidMasse moléculaire :452.46Dehydroisoandrosterone 3-acetate
CAS :Dehydroisoandrosterone 3-acetate (Prasterone acetate) is a primary C19 steroid generated by the adrenal cortex.Formule :C21H30O3Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :330.46RD162
CAS :RD162 is a non-steroidal antiandrogen (NSAA) specifically binding to the androgen receptor (AR).Formule :C22H16F4N4O2SDegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :476.45Ref: TM-T21740
1mg44,00€5mg113,00€1mL*10mM (DMSO)137,00€10mg177,00€25mg371,00€50mg553,00€100mg788,00€Premarin
CAS :Premarin (Estrone 3-sulfate) is an an estrogen sulfate with neuroprotective actions during traumatic brain injury.Formule :C18H22O5SDegré de pureté :99.74%Couleur et forme :SoildMasse moléculaire :350.43Ref: TM-T36857L
1mg175,00€5mg394,00€1mL*10mM (DMSO)413,00€10mg582,00€25mg888,00€50mg1.243,00€100mg1.674,00€Benazeprilat
CAS :Benazeprilat(CGS 14831) is an orally active active metabolite of Benazepril.Benazeprilat has potent antihypertensive activity and can be used in combinationFormule :C22H24N2O5Degré de pureté :99.23%Couleur et forme :Crystalline SolidMasse moléculaire :396.44Norethynodrel
CAS :Norethynodrel, a synthetic hormone, mimics progesterone, treats uterine bleeding/endometriosis, and is used with mestranol as a contraceptive.Formule :C20H26O2Degré de pureté :98%Couleur et forme :Crystals From Aqueous Methanol SolidMasse moléculaire :298.42Estetrol
CAS :Estetrol (Donesta), a fetal liver-synthesized estrogen, selectively modulates estrogen receptors and may ease menopausal symptoms.Formule :C18H24O4Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :304.38Ref: TM-T15248
1mg39,00€5mg84,00€1mL*10mM (DMSO)93,00€10mg130,00€25mg268,00€50mg462,00€100mg773,00€200mg1.044,00€ARD-266
CAS :ARD-266 is a PROTAC degrader based on the von Hippel-Lindau E3 ligase that induces the degradation of AR proteins and is useful in prostate cancer research.Formule :C52H59ClN6O7Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :915.514,4'-(Cyclohexylidenemethylene)diphenol
CAS :4,4'-(Cyclohexylidenemethylene)diphenol (Compound 2) is a symmetrical cyclic non-steroidal estrogen. It exhibits high binding affinity to estrogen receptors ERα and ERβ.Formule :C19H20O2Couleur et forme :SolidMasse moléculaire :280.36
![[DPro10] Dynorphin A (1-11)acetate,porcine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT76341L.webp&w=3840&q=75)
