Endocrinologie/Hormones
Les inhibiteurs en endocrinologie/hormonaux sont des composés qui bloquent l'action des hormones ou interfèrent avec les voies de signalisation hormonales. Ces inhibiteurs sont essentiels pour étudier la régulation des systèmes endocriniens et pour développer des traitements pour les maladies liées aux hormones, telles que le diabète, les troubles de la thyroïde et les cancers hormonodépendants. En modulant l'activité hormonale, ces inhibiteurs peuvent aider à élucider les interactions complexes au sein du système endocrinien. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité en endocrinologie/hormonaux pour soutenir vos recherches en endocrinologie, pharmacologie et sciences médicales.
Sous-catégories appartenant à la catégorie "Endocrinologie/Hormones"
- Récepteur des androgènes(229 produits)
- Annexine A(16 produits)
- Aromatase(23 produits)
- Récepteur d'œstrogène/progestatif(66 produits)
- GPR(1 produits)
- Récepteur des glucocorticoïdes(164 produits)
- LHRH(2 produits)
- Récepteur opioïde(327 produits)
- Récepteur de prostaglandine(122 produits)
- RAAS(89 produits)
- Réductase(51 produits)
- Somatostatine(57 produits)
- Récepteur des hormones thyroïdiennes (THR)(34 produits)
- Récepteur de la vasopressine(48 produits)
Affichez 6 plus de sous-catégories
3419 produits trouvés pour "Endocrinologie/Hormones"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
RJG-2051
CAS :RJG-2051 is a selective covalent inhibitor of aldo-keto reductase family 1 member C3 (AKR1C3), with an IC50 value of 13 nM. It interferes with the metabolism of substrates such as androgens, estrogens, and prostaglandins through AKR1C3. RJG-2051 holds potential for cancer research.Formule :C26H31N5O4SCouleur et forme :SolidMasse moléculaire :509.62OSU-ERb-12
CAS :OSU-ERb-12 is an ERβ agonist that suppresses ovarian cancer cell proliferation both in vitro and in vivo, and decreases the expression of Snail [1] [2].Formule :C15H30B10O2Couleur et forme :SolidMasse moléculaire :350.51Mu opioid receptor antagonist 4
Compound 31: Potent, selective MOR antagonist; crosses blood-brain barrier; Ki & EC50: 0.38 nM; useful for OUD research.Formule :C25H28N2O4SCouleur et forme :SolidMasse moléculaire :452.57Estrogen receptor antagonist 6
CAS :Estrogen receptor antagonist 6 is a potent blocker of estrogen signaling, regulating various biological effects. (Compound 166)Formule :C25H31F3N2O3Couleur et forme :SolidMasse moléculaire :464.52A 74273
CAS :A 74273, a nonpeptidic and renin inhibitor, may be used to treat cardiovascular diseases due to renin inhibition.Formule :C44H74N4O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :787.08Pentomone
CAS :Pentomone (LY-113935) is an anti-androgen compound that acts as a prostate growth inhibitor.Formule :C24H26O5Couleur et forme :SolidMasse moléculaire :394.46Elacestrant S enantiomer dihydrochloride
Elacestrant (RAD1901) dihydrochloride, an oral ERR degrader, has IC50 of 48 nM (ERα) and 870 nM (ERβ). Its S enantiomer has low activity.Formule :C30H40Cl2N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :531.56MK-6913
CAS :MK-6913 is a potent and selective agonist of estrogen receptor β.Formule :C25H27N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :401.5ERα degrader 11
CAS :ERα degrader11 (compound B16) is a selective estrogen receptor degrader designed for use as a probe in examining the ER status within ER-positive breast cancer cells.Formule :C28H27F3N2O3Couleur et forme :SolidMasse moléculaire :496.52σ1 Receptor/μ Opioid receptor modulator 2
CAS :Compound 4x, also known as σ1 Receptor/μOpioid receptormodulator 2, acts as a μOR agonist and a σ1R antagonist, exhibiting a potent μOR EC50 of 0.6 nM and strong σ1R inhibitory activity (Ki: 363.7 nM). It demonstrates significant analgesic effects in various pain models.Formule :C23H31N3OMasse moléculaire :365.51CCG258747
CAS :CCG258747 is a novel, selective inhibitor of the GRK2 subfamily.Formule :C28H27FN4O4Couleur et forme :SolidMasse moléculaire :502.54Sunobinop
CAS :Sunobinop (S 117957) is an opioid receptor-like orphan receptor (ORL1) modulator.Formule :C26H33N3O3Couleur et forme :SolidMasse moléculaire :435.56Daeatal
CAS :Dynorphin A ethylamide (1-9), the opioid activities were examined in the bioassays.Formule :C56H93N19O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1192.46GPR84 antagonist 3
CAS :Potent GPR84 antagonist 3 (compound 42), pIC50 8.28, inhibits GTPγS, with good pharmacokinetics.Formule :C29H27N5OCouleur et forme :SolidMasse moléculaire :461.56ADX61623
CAS :ADX61623 is an effective negative allosteric modulator (NAM) of the follicle-stimulating hormone receptor (FSHR). It also exhibits activity on the luteinizing hormone receptor (LH-R) but is inactive on the thyroid-stimulating hormone (TSH) receptor. ADX61623 can be utilized in research on estrogen-dependent diseases.Formule :C19H20N2O3Couleur et forme :SolidMasse moléculaire :324.37BNTX maleate
CAS :δ1 opioid receptor antagonistFormule :C31H31NO8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :545.58JNJ-1250132
CAS :JNJ-1250132 is a steroidal progesterone receptor modulator that inhibits binding of the receptor to DNA in vitro.Formule :C33H41NO4Couleur et forme :SolidMasse moléculaire :515.68Fonsartan free acid
CAS :Fonsartan: Angiotensin receptor blocker, halts angiotensin II effects on rat vascular cells.Formule :C26H32N4O5S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :544.69rel-SB-612111 hydrochloride
CAS :NOP receptor antagonistFormule :C24H30Cl3NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :454.86ACT 178882
CAS :ACT 178882 is a new Renin inhibitor (IC50: 1.4 nM).Formule :C33H38Cl3N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :647.03MB-07344 sodium
"MB-07344 sodium is a TR-β agonist with a 2.17 nM Ki, boosts Atorvastatin's cholesterol-lowering effects in various animals."Formule :C19H25NaO5PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :387.36TRβ agonist 1
CAS :TRβ Agonist 1, a selective and mutation-sensitive thyroid hormone receptor β (TRβ) agonist, demonstrates an EC50 value of 21 nM.Formule :C29H25FN2O8Couleur et forme :SolidMasse moléculaire :548.52ERRγ agonist-1
ERRγ agonist-1 can be used in neuropsychological disorders research.Formule :C17H21N5OCouleur et forme :SolidMasse moléculaire :311.38Estrogen receptor-agonist-1
CAS :Estrogen receptor-agonist-1 (compound 4e) is an estrogen receptor (ER) agonist that binds to ERα with high affinity.Formule :C24H22N2O2Couleur et forme :SolidMasse moléculaire :370.444SDM25N hydrochloride
CAS :δ receptor antagonistFormule :C26H27ClN2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :450.96EN171
CAS :EN171, a covalent ligand, selectively binds to C38 and C96 on 14-3-3, intensifying 14-3-3's interactions with ERα, YAP, and TAZ. This action impairs both estrogen receptor and Hippo pathway transcriptional activities. Beyond serving as a molecular glue to augment native protein interactions, EN171 also functions as a covalent recruiter for 14-3-3 in heterobifunctional molecules. This facilitates the sequestration of nuclear neo-substrates, such as BRD4 and BLC6, into the cytosol.Formule :C17H22N2OCouleur et forme :SolidMasse moléculaire :270.37GLPG0974
CAS :GLPG0974 is an antagonist of FFA2/GPR43 with IC50 of 9 nM.Formule :C25H25ClN2O4SDegré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :484.99L-371,257
CAS :L-371,257 is a competitive antagonist of oxytocin receptor with pA2 of 8.4 and Ki of 19 nM. L-371,257 shows a Ki of 3.7 nM for vasopressin receptor 1a.Formule :C28H33N3O6Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :507.58Cort108297
CAS :Cort108297: selective GR modulator/antagonist, high GR affinity (Ki: 0.45nM), no other steroid receptor affinity.Formule :C26H25F4N3O3SDegré de pureté :98.36% - 99.94%Couleur et forme :SolidMasse moléculaire :535.55Ref: TM-T15000
1mg260,00€5mg590,00€1mL*10mM (DMSO)708,00€10mg859,00€25mg1.341,00€50mg1.783,00€100mg2.602,00€ZD 7155 hydrochloride
CAS :ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist.Formule :C26H27ClN6ODegré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :474.98Ref: TM-T13390
1mg42,00€5mg88,00€1mL*10mM (DMSO)90,00€10mg135,00€25mg235,00€50mg396,00€100mg635,00€200mg887,00€(E/Z)-GSK5182
CAS :GSK5182 is a racemic mix of (E/Z) isomers, a selective ERRγ inverse agonist (IC50: 79 nM), and induces ROS in liver cancer.Formule :C27H31NO3Degré de pureté :97.58%Couleur et forme :SolidMasse moléculaire :417.54Ref: TM-T7709
1mg77,00€5mg167,00€1mL*10mM (DMSO)177,00€10mg260,00€25mg477,00€50mg707,00€100mg1.063,00€LSZ-102
CAS :LSZ-102 is an effective and selective degrader of estrogen receptor (IC50 = 0.2 nM) and can be used in studies about ERα positive breast cancer.Formule :C25H17F3O4SDegré de pureté :98.56%Couleur et forme :SolidMasse moléculaire :470.46PSN632408
CAS :PSN632408 is an optimized agonist of GPR119 receptors that display similar potency to OEA at both recombinant mouse and human GPR119 receptors (EC50: 5.6 and 7.9 uM, respectively).Formule :C18H24N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :360.41Mapracorat
CAS :Mapracorat (ZK-245186, BOL-303242X) is a selective glucocorticoid receptor agonist,anti-inflammatory agent for atopic dermatitis and allergic conjunctivitis.Formule :C25H26F4N2O2Couleur et forme :SolidMasse moléculaire :462.48ML314
CAS :ML314 is a brain-permeable nonpeptide β-inhibin-biased neurotensin NTR1 receptor agonist (EC50: 1.9 μM), a biased neurotensin receptor ligand for methamphetamine abuse that inhibits NTR2 and GPR35.Formule :C24H28N4O3Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :420.504(S)-Mapracorat
CAS :(S)-Mapracorat is a selective and less active agonist of the glucocorticoid receptor.Formule :C25H26F4N2O2Couleur et forme :SolidMasse moléculaire :462.48Relacorilant
CAS :Relacorilant is an oral glucocorticoid receptor antagonist with Ki of 7.2 nM, potential for treating Cushing's syndrome.
Formule :C27H22F4N6O3SDegré de pureté :98.53% - 99%Couleur et forme :SolidMasse moléculaire :586.56Ref: TM-T16727
Produit arrêtéRat VLDL(Very Low Density Lipoprotein) ELISA Kit
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat VLDL. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat VLDL. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat VLDL, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat VLDL in the samples is then determined by comparing the OD of the samples to the standard curve.
Horse IGF1(Insulin Like Growth Factor 1) ELISA Kit
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Horse IGF1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Horse IGF1. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Horse IGF1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Horse IGF1 in the samples is then determined by comparing the OD of the samples to the standard curve.
Mouse MDA(Malondialdehyde) ELISA Kit
This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Mouse MDA protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse MDA. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse MDA in the samples is then determined by comparing the OD of the samples to the standard curve.
AZD9496 maleate
CAS :AZD9496 maleate is a highly potent and selective antagonist of the estrogen receptor alpha (ERα), exhibiting an IC50 value of 0.28 nM. This compound, AZD9496 maleate, is an orally bioavailable selective estrogen receptor degrader (SERD).Formule :C29H29F3N2O6Couleur et forme :SolidMasse moléculaire :558.554Omzotirome
CAS :Omzotirome (TRC150094) is a functional analog of iodothyronines and holds potential for research on hyperlipidemia (WO2008149379).Formule :C19H24N2O3Couleur et forme :SolidMasse moléculaire :328.412L-372662
CAS :L-372662 is bioactive chemical.Formule :C33H38N4O6Couleur et forme :SolidMasse moléculaire :586.68ERB-196
CAS :Erb-196 is an estrogen receptor-receptor agonist with non-steroidal selectivity.Formule :C17H10FNO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :279.2721-Acetoxypregna-1,4,9(11),16-tetraene-3,20-dione
21-Acetoxypregna-1,4,9(11),16-tetraene-3,20-dione is a valuable organic compound for life sciences research [Catalog No.: T67476, CAS No.: 37413-91-5].Formule :C23H26O4Couleur et forme :SolidMasse moléculaire :366.457GPR109 receptor agonist-2
CAS :Compound 5, a selective GPR109a agonist, exhibits a pEC50 value of 5.53 [1].Formule :C7H10N2O2Couleur et forme :SolidMasse moléculaire :154.17Phosphoramidon Disodium
CAS :Phosphoramidon Disodium (Phosphoramidon Disodium Salt) Salt is a metalloendopeptidase inhibitor, widely used as a biochemical tool.Formule :C23H34N3Na2O10PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :588.48PF-998425
CAS :non-steroidal androgen receptor (AR) antagonistFormule :C14H14F3NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :269.26Cebranopadol
CAS :Cebranopadol (GRT6005) is an analgesic NOP and opioid receptor agonist with Kis of 0.9 nM, 0.7 nM, 2.6 nM, 18 nM for human NOP, μ-opioid (MOP), κ-opioid (KOP)
Formule :C24H27FN2ODegré de pureté :98.32% - 99.78%Couleur et forme :SolidMasse moléculaire :378.48Ref: TM-T5167
Produit arrêtéPamoic acid
CAS :Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.
Formule :C23H16O6Degré de pureté :99.99%Couleur et forme :Fine Yellow PowderMasse moléculaire :388.37
