Endocrinologie/Hormones
Les inhibiteurs en endocrinologie/hormonaux sont des composés qui bloquent l'action des hormones ou interfèrent avec les voies de signalisation hormonales. Ces inhibiteurs sont essentiels pour étudier la régulation des systèmes endocriniens et pour développer des traitements pour les maladies liées aux hormones, telles que le diabète, les troubles de la thyroïde et les cancers hormonodépendants. En modulant l'activité hormonale, ces inhibiteurs peuvent aider à élucider les interactions complexes au sein du système endocrinien. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité en endocrinologie/hormonaux pour soutenir vos recherches en endocrinologie, pharmacologie et sciences médicales.
Sous-catégories appartenant à la catégorie "Endocrinologie/Hormones"
- Récepteur des androgènes(211 produits)
- Annexine A(11 produits)
- Aromatase(20 produits)
- Récepteur d'œstrogène/progestatif(50 produits)
- GPR(1 produits)
- Récepteur des glucocorticoïdes(154 produits)
- LHRH(1 produits)
- Récepteur opioïde(298 produits)
- Récepteur de prostaglandine(120 produits)
- RAAS(87 produits)
- Réductase(52 produits)
- Somatostatine(49 produits)
- Récepteur des hormones thyroïdiennes (THR)(26 produits)
- Récepteur de la vasopressine(45 produits)
Affichez 6 plus de sous-catégories
3193 produits trouvés pour "Endocrinologie/Hormones"
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Floramanoside C
CAS :<p>Floramanoside C exhibits 2,2-diphenyl-1-picrylhydrazyl scavenging and aldose reductase inhibitory activities [1].</p>Formule :C21H18O15Couleur et forme :SolidMasse moléculaire :510.36Dynorphin A (1-8)
CAS :<p>Dynorphin (1-8) is an opioid octapeptide from the porcine hypothalamus. It comprises the N-terminal eight residues of dynorphin.</p>Formule :C46H72N14O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :981.15ICI 174,864
CAS :<p>Selective δ opioid antagonist. Exhibits partial agonist in vitro activity at δ receptors at high concentrations.</p>Formule :C38H53N5O7Degré de pureté :98%Couleur et forme :White SolidMasse moléculaire :691.87SL910102
CAS :<p>SL910102 is a nonpeptide angiotensin antagonist of the AT1 receptor.</p>Formule :C30H30N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :490.60[Ala17]-MCH TFA
<p>'[Ala17]-MCH TFA is an MCH analogue, a selective MCHR1 ligand (Ki=0.16 nM) with high affinity (Kd=0.37 nM), and low MCHR2 affinity (Ki=34 nM).</p>Formule :C99H156F3N29O28S4Couleur et forme :SolidMasse moléculaire :2385.73Cl-4AS-1
CAS :steroidal androgen receptor agonistFormule :C26H33ClN2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :441.01DPP-4/GPR119 modulator 1
CAS :<p>Orally active DPP-4 inhibitor/GPR119 agonist, Compound 22 lowers glucose, moderate hERG inhibition, IC50 4.9 µM, for diabetes research.</p>Formule :C30H39ClN10O3Couleur et forme :SolidMasse moléculaire :623.15Gluten Exorphin B5
CAS :<p>Gluten exorphin B5 (GE-B5) is a food-derived opioid peptide identified in digests of wheat gluten.</p>Formule :C30H38N6O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :594.66MCH(human, mouse, rat) TFA
<p>MCH TFA, a peptide, selectively binds MCH1R and MCH2R with IC50 of 0.3nM, 1.5nM; EC50s are 3.9nM (MCH1R) and 0.1nM (MCH2R) in CHO cells.</p>Formule :C107H161F3N30O28S4Couleur et forme :SolidMasse moléculaire :2500.86Cebranopadol hemicitrate
CAS :<p>Cebranopadol hemicitrate is a NOP and opioid receptor agonist that targets human NOP, MOP, KOP, and δ-opioid peptide (DOP) receptors, with Ki/EC50 values of 0.9 nM/13 nM, 0.7 nM/1.2 nM, 2.6 nM/17 nM, and 18 nM/110 nM, respectively. It is used in studies of acute and chronic pain.</p>Couleur et forme :SolidCTOP
CAS :<p>Potent μ-receptor antagonist, Ki=0.96nM, ineffective at δ (>10,000nM). Alters behavior in vivo, boosts K+ currents in rat neurons in vitro, μ-independent.</p>Formule :C50H67N11O11S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1062.28TRV-120027
CAS :<p>TRV120027: β-arrestin-1-biased agonist, angiotensin II type 1 receptor, reduces vasoconstriction, boosts heart muscle contraction.</p>Formule :C43H67N13O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :926.09OT antagonist 1 demethyl derivative
<p>OT antagonist 1 demethyl derivative is the demethyl derivative of OT antagonist 1. OT antagonist 1 is a selective Oxytocin antagonist (Ki of 50 nM. )</p>Formule :C21H20N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :376.41Aclerastide
CAS :<p>Aclerastide, an angiotensin receptor agonist, decreases fibrosis in wounds; effect increases with use duration, blocked by AT antagonist.</p>Formule :C42H64N12O11Couleur et forme :SolidMasse moléculaire :913.03Locicortolone
CAS :<p>Locicortolone is a synthetic glucocorticoid corticosteroid which was never marketed.</p>Formule :C22H28Cl2O3Couleur et forme :SolidMasse moléculaire :411.36AL-438
CAS :<p>AL-438 is a non-steroidal selective glucocorticoid receptor modulator.</p>Formule :C23H25NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :347.45Linuron
CAS :<p>Linuron herbicide disrupts photosynthesis and acts as an androgen receptor antagonist.</p>Formule :C9H10Cl2N2O2Degré de pureté :99.08%Couleur et forme :White Crystalline Solid Linuron Is A Colorless Crystals Non Corrosive Used As An HerbicideMasse moléculaire :249.09Hemorphin-7
CAS :<p>Hemorphin-7, an atypical opioid peptide from hemoglobin, may enhance memory, promote cell growth, and is a potential breast cancer biomarker.</p>Formule :C49H64N12O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :997.11Ditekiren
CAS :<p>Ditekiren is a renin inhibitor with orally active.</p>Formule :C50H75N9O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :930.19PROTAC ER Degrader-14
CAS :<p>PROTAC ER Degrader-14 (compound 86) is a PROTAC-type estrogen receptor/ERR degrader. It comprises an E3 ubiquitin ligase ligand (blue part) (S)-Deoxy-thalidomide, a PROTAC linker (black part) N-Boc-piperazine, and a target protein ligand (red part) ER ligand-6. The combination of the E3 ligase and linker forms tert-Butyl (S)-4-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)piperazine-1-carboxylate.</p>Formule :C44H46FN5O5Couleur et forme :SolidMasse moléculaire :743.865RTI-13951-33 hydrochloride
RTI-13951-33 HCl: potent, selective GPR88 agonist; brain-penetrant; EC50 = 25nM; curbs rat alcohol behaviors.Formule :C28H35Cl2N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :532.5ARD-69
<p>ARD-69, a potent PROTAC, degrades AR in prostate cancer, with low DC50 values in AR+ cell lines, and suppresses AR gene expression.</p>Formule :C62H74ClFN8O7SCouleur et forme :SolidMasse moléculaire :1129.83GLL 398
CAS :<p>GLL 398 is an orally active and selective degrader of estrogen receptor with an IC50 of 1.14 nM. GLL 398 blocks tumor growth in xenograft breast cancer models.</p>Formule :C25H23BO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :398.26D3R/MOR antagonist 1
<p>Compound 114 (D3R/MOR antagonist 1) exhibits dual antagonistic activity at dopamine D3 receptors (D3R) and mu-opioid receptors (MOR), with K i values of 46.5 nM</p>Formule :C22H27Cl2N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :420.38Melanin Concentrating Hormone, salmon TFA
<p>MCH (salmon) TFA is a 19-amino-acid neuropeptide affecting appetite, energy, sleep, and heart health via GPCR SLC-1/GPR24 and MCHR2.</p>Formule :C91H140F3N27O26S4Couleur et forme :SolidMasse moléculaire :2213.5PROTAC ERα Degrader-8
CAS :<p>PROTAC ERα Degrader-8 (compound ii-56), a highly potent degrader of Erα, achieves a DC50 of just 0.000006 μM in MCF7 cells [1].</p>Formule :C47H51N5O4Couleur et forme :SolidMasse moléculaire :749.94[Arg14,Lys15]Nociceptin
CAS :<p>Potent NOP agonist (EC50 = 1 nM), >875x selective vs opioid receptors; outperforms nociceptin in vivo, increases pain perception, reduces movement.</p>Formule :C82H137N31O22Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1909.18CP-472555
CAS :<p>CP-472555 is a selective nonsteroidal glucocorticoid receptor antagonist with anti-GR and anti-obesity activity in animal models.</p>Formule :C31H32N2O2Couleur et forme :SolidMasse moléculaire :464.60[Nphe1]Nociceptin(1-13)NH2
CAS :<p>Competitive nociceptin receptor antagonist with pKi=8.4; no agonist activity; blocks nociceptin effects in vitro/in vivo.</p>Formule :C61H100N22O15Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1381.6Prednicarbate
CAS :<p>Prednicarbate (Hoe 777), a corticosteroid, has antipruritic, anti-inflammatory effects, reduces lymphocytes, and inhibits vasodilators.</p>Formule :C27H36O8Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :488.57Koreanoside E
CAS :<p>Koreanoside E is a useful organic compound for research related to life sciences. The catalog number is T125538 and the CAS number is 1804014-67-2.</p>Formule :C27H30O11Couleur et forme :SolidMasse moléculaire :530.526BAM-22P
CAS :<p>Bovine adrenal medulla docosapeptide (BAM-22P) is a potent opioid agonist, derived from the proenkephalin A gene, which is present in the adrenal medulla.</p>Formule :C130H184N38O31S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2839.22PROTAC ER Degrader-15
<p>PROTAC ER Degrader-15 (Compound 40) is an orally active estrogen receptor (ER) degrader with anticancer properties, suitable for breast cancer research.</p>Formule :C47H47F4N5O5Couleur et forme :SolidMasse moléculaire :837.9PROTAC ERα Degrader-7
CAS :<p>PROTAC ERα Degrader-7 (Compound i-320) is a powerful PROTAC degrader targeting the estrogen receptor alpha (ERα), exhibiting a DC50 of 0.000006 µM. This compound consists of a cereblon-binding segment, LBM, connected to ERBM, an ERα-binding ligand that includes a benzofused partially saturated 6-membered carbocyclic or heterocyclic ring [1].</p>Formule :C46H49F2N5O4Couleur et forme :SolidMasse moléculaire :773.91[Nphe1]Nociceptin(1-13)NH2 TFA
<p>[Nphe1]Nociceptin(1-13)NH2 is a selective nociceptin receptor antagonist with potential analgesic properties, pKi=8.4, pA2=6.0.</p>Formule :C63H101F3N22O17Couleur et forme :SolidMasse moléculaire :1495.61AKR1C3-IN-9
<p>AKR1C3-IN-9: Selective AKR1C3 inhibitor, IC50=8.92 nM; reverses DOX resistance in breast cancer.</p>Formule :C20H20N2O4Degré de pureté :99.98%Couleur et forme :SoildMasse moléculaire :352.38MT-7716 free base
CAS :MT-7716: selective NOP agonist, potential in preventing alcohol abuse/relapse.Formule :C27H28N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :440.54Abaloparatide
CAS :<p>Abaloparatide (BA 058) is a selective PTHR1 analog that promotes bone growth and may be researched for osteoporosis.</p>Formule :C174H300N56O49Couleur et forme :SolidMasse moléculaire :3960.59PROTAC ERα Degrader-2
CAS :<p>PROTAC ERα Degrader-2 is composed of a cIAP1 ligand binding group, a linker, and an estrogen receptor α (ERα) binding group, serving as an ERα degrader.</p>Formule :C42H61N5O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :763.96RLA-4842
<p>RLA-4842: iron-based anti-androgen; inhibits mCRPC cell proliferation.</p>Formule :C42H46F3N5O8SCouleur et forme :SolidMasse moléculaire :837.9Nociceptin(1-7)
CAS :<p>Bioactive metabolite of nociceptin, antagonist of nociceptin-induced hyperalgesia</p>Formule :C31H41N7O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :655.709EX-A5386
CAS :<p>EX-A5386 (Glucocorticoid receptor modulator-1) is a potent glucocorticoid receptor modulator, IC50/EC50<100nM.</p>Formule :C29H27FN4O2Degré de pureté :99.89%Couleur et forme :SoildMasse moléculaire :482.55Rofleponide
CAS :<p>Rofleponide is a synthetic glucocorticosteroid with a high affinity for the rat thymus glucocorticoid receptor.</p>Formule :C25H34F2O6Degré de pureté :99.32%Couleur et forme :SolidMasse moléculaire :468.53Triphenylethylene
CAS :<p>Compound PDK0283, with CAS No. 58-72-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0283 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formule :C20H16Couleur et forme :White PowderMasse moléculaire :256.3418-Oxocortisol
CAS :<p>18-Oxocortisol, a naturally occurring mineralocorticoid and adrenal biomarker, is produced by CYP11B2.</p>Formule :C21H28O6Couleur et forme :SolidMasse moléculaire :376.449LO-4-25
<p>LO-4-25 is a covalent degrader targeting the androgen receptor (AR) and its splice variant AR-V7. It covalently binds to the E3 ubiquitin ligase CUL4 DCAF16, facilitating the ubiquitination of both AR and AR-V7, which are then recognized and degraded by the proteasome, leading to reduced protein levels of AR and AR-V7 in cells. LO-4-25 is promising for research on androgen-independent prostate cancer.</p>Couleur et forme :Odour SolidARD-2051
CAS :<p>ARD-2051 is a potent, orally active proteolysis-targeting chimera degrader of the androgen receptor (AR), exhibiting DC50 values of 0.6 nM in degrading AR</p>Formule :C43H45ClN8O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :789.32ERα degrader 12
<p>ERα degrader12 (Compound RA3) is an estrogen receptor alpha (ERα) degrader with antitumor properties. It significantly suppresses tumor growth in a xenograft mouse model of breast cancer.</p>Formule :C39H41NO9SCouleur et forme :SolidMasse moléculaire :699.81PROTAC ER Degrader-2
PAC, based on WO2017201449A1's LP2, enhances ERα degradation; used in making ADCs with PROTAC-linker, it's attached to antibodies.Formule :C89H104N12O15Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1581.85RS 21314
CAS :RS 21314 is a thiol ester corticosteroid that is topical.Formule :C24H30F2O5SCouleur et forme :SolidMasse moléculaire :468.55
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