Endocrinologie/Hormones
Les inhibiteurs en endocrinologie/hormonaux sont des composés qui bloquent l'action des hormones ou interfèrent avec les voies de signalisation hormonales. Ces inhibiteurs sont essentiels pour étudier la régulation des systèmes endocriniens et pour développer des traitements pour les maladies liées aux hormones, telles que le diabète, les troubles de la thyroïde et les cancers hormonodépendants. En modulant l'activité hormonale, ces inhibiteurs peuvent aider à élucider les interactions complexes au sein du système endocrinien. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité en endocrinologie/hormonaux pour soutenir vos recherches en endocrinologie, pharmacologie et sciences médicales.
Sous-catégories appartenant à la catégorie "Endocrinologie/Hormones"
- Récepteur des androgènes(211 produits)
- Annexine A(11 produits)
- Aromatase(20 produits)
- Récepteur d'œstrogène/progestatif(50 produits)
- GPR(1 produits)
- Récepteur des glucocorticoïdes(154 produits)
- LHRH(1 produits)
- Récepteur opioïde(298 produits)
- Récepteur de prostaglandine(120 produits)
- RAAS(87 produits)
- Réductase(52 produits)
- Somatostatine(49 produits)
- Récepteur des hormones thyroïdiennes (THR)(26 produits)
- Récepteur de la vasopressine(45 produits)
Affichez 6 plus de sous-catégories
3193 produits trouvés pour "Endocrinologie/Hormones"
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OT-R antagonist 2
CAS :OT-R antagonist 2 is a nonpeptide low molecular weight antagonist of OT-R .Formule :C28H29N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :471.55D3R/MOR antagonist 1
<p>Compound 114 (D3R/MOR antagonist 1) exhibits dual antagonistic activity at dopamine D3 receptors (D3R) and mu-opioid receptors (MOR), with K i values of 46.5 nM</p>Formule :C22H27Cl2N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :420.38VinclozolinM2-2204
<p>VinclozolinM2-2204 is an androgen receptor AUTOTAC degrader with a DC50 of 200 nM in LNCaP prostate cancer cells. It induces the formation of AR+LC3+ autophagic membranes and is applicable for cancer research.</p>Formule :C43H51Cl2N3O9Masse moléculaire :823.30024TAN67
CAS :<p>TAN67 is the first effective selective non-peptide delta1 opioid receptor.</p>Formule :C23H26Br2N2OCouleur et forme :SolidMasse moléculaire :506.282BigLEN(mouse)
CAS :<p>GPR171 agonist from ProSAAS controls mouse appetite, reduces glutamate in paraventricular neurons via G protein.</p>Formule :C78H130N24O22Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1756.03OT antagonist 1 demethyl derivative
<p>OT antagonist 1 demethyl derivative is the demethyl derivative of OT antagonist 1. OT antagonist 1 is a selective Oxytocin antagonist (Ki of 50 nM. )</p>Formule :C21H20N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :376.41Estrogen receptor modulator 13
<p>Estrogen receptor modulator13 (Compound 5D) is an estrogen receptor antagonist with significant cytotoxic effects on MCF7 cells, exhibiting an IC50 value of 8.50 μM. Estrogen receptor modulator13 holds potential for breast cancer research.</p>Formule :C25H19ClN2O2SCouleur et forme :SolidMasse moléculaire :446.08558Koreanoside E
CAS :<p>Koreanoside E is a useful organic compound for research related to life sciences. The catalog number is T125538 and the CAS number is 1804014-67-2.</p>Formule :C27H30O11Couleur et forme :SolidMasse moléculaire :530.526Vasopressin Dimer (anti-parallel) (TFA)
<p>Vasopressin Dimer (anti-parallel) TFA, an anti-parallel dimer form of vasopressin, has the capability to activate four G protein-coupled receptors: V1aR, V1bR,</p>Formule :C94H131F3N30O26S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2282.49Flucloronide
CAS :<p>Flucloronide is a corticosteroid for topical use on the skin. It has anti-inflammatory properties.</p>Formule :C24H29Cl2FO5Couleur et forme :SolidMasse moléculaire :487.39PROTAC ER Degrader-14
CAS :<p>PROTAC ER Degrader-14 (compound 86) is a PROTAC-type estrogen receptor/ERR degrader. It comprises an E3 ubiquitin ligase ligand (blue part) (S)-Deoxy-thalidomide, a PROTAC linker (black part) N-Boc-piperazine, and a target protein ligand (red part) ER ligand-6. The combination of the E3 ligase and linker forms tert-Butyl (S)-4-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)piperazine-1-carboxylate.</p>Formule :C44H46FN5O5Couleur et forme :SolidMasse moléculaire :743.865β-Endorphin, equine TFA
<p>β-Endorphin, equine TFA, an endogenous opioid peptide, demonstrates high affinity binding to μ/δ opioid receptors and possesses analgesic properties [1] [2] [3</p>Formule :C156H249F3N42O46SCouleur et forme :SolidMasse moléculaire :3537.96Frakefamide TFA
<p>Frakefamide TFA: potent, peripherally active μ-opioid agonist; doesn't cross blood-brain barrier.</p>Formule :C32H35F4N5O7Couleur et forme :SolidMasse moléculaire :677.64[Orn8]-Urotensin II
CAS :<p>[Orn8]-Urotensin II is a Urotensin receptor ligand and a partial agonist at Urotensin receptors.</p>Formule :C63H83N13O18S2Couleur et forme :SolidMasse moléculaire :1374.55CP-472555
CAS :<p>CP-472555 is a selective nonsteroidal glucocorticoid receptor antagonist with anti-GR and anti-obesity activity in animal models.</p>Formule :C31H32N2O2Couleur et forme :SolidMasse moléculaire :464.60DP32
CAS :<p>DP32 is a dual-function compound incorporating an opioid receptor (MOP) agonist and a neuropeptide FF receptor (NPFFR) antagonist. It is applicable in analgesia-related research.</p>Formule :C57H77N13O7Couleur et forme :SolidMasse moléculaire :1056.30DP50
DP50 is a bifunctional compound containing both an opioid receptor agonist (MOP) and a neuropeptide FF receptor (NPFFR) antagonist. It can be utilized in studies related to analgesia.Formule :C58H72N8O7Masse moléculaire :992.5524ERRγ agonist-2
CAS :<p>ERRγ agonist-2 is a potent and selective ERRγ inverse agonist with a K d value of 6.5 μM.</p>Formule :C27H21N5O2Couleur et forme :SolidMasse moléculaire :447.49Neuropeptide AF (human) acetate
<p>Neuropeptide AF (human) acetate (Neuropeptide AF (human) acetate (192387-38-5 Free base)) is an anti-opioid neuropeptide, a Neuropeptide AF (human) derivative,</p>Degré de pureté :99.89%Couleur et forme :SoildNociceptin(1-7)
CAS :<p>Bioactive metabolite of nociceptin, antagonist of nociceptin-induced hyperalgesia</p>Formule :C31H41N7O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :655.709Nurr1 agonist 5
<p>Compound 5o, a Nurr1 agonist, exhibits neuroprotective properties as a transcription factor Nurr1 agonist, possessing a dissociation constant (Kd) of 0.5 μM and</p>Couleur et forme :Odour Solid3-epi-25-hydroxy Vitamin D3
CAS :<p>3-epi-25-hydroxy Vitamin D3 lowers serum PTH in male weanling rats at 0.5 and 1 IU/g doses; doesn't affect females.</p>Formule :C27H44O2Couleur et forme :SolidMasse moléculaire :400.64Cebranopadol hemicitrate
CAS :<p>Cebranopadol hemicitrate is a NOP and opioid receptor agonist that targets human NOP, MOP, KOP, and δ-opioid peptide (DOP) receptors, with Ki/EC50 values of 0.9 nM/13 nM, 0.7 nM/1.2 nM, 2.6 nM/17 nM, and 18 nM/110 nM, respectively. It is used in studies of acute and chronic pain.</p>Couleur et forme :SolidCTOP
CAS :<p>Potent μ-receptor antagonist, Ki=0.96nM, ineffective at δ (>10,000nM). Alters behavior in vivo, boosts K+ currents in rat neurons in vitro, μ-independent.</p>Formule :C50H67N11O11S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1062.28Thyroxine sulfate
CAS :<p>Thyroxine sulfate is a sulfoconjugated derivative of Thyroxine and is also a metabolite of Thyroxine.</p>Formule :C15H11I4NO7SCouleur et forme :SolidMasse moléculaire :856.93PIPE-3297
PIPE-3297 (compound 25) is a selective kappa opioid receptor (KOR) agonist that activates the G protein signaling pathway with an EC50 of 1.1 nM and exhibits low β-arrestin-2 recruitment activity (10%). Additionally, PIPE-3297 promotes myelination and has anti-inflammatory properties.Formule :C23H30N2OMasse moléculaire :350.23581[Arg14,Lys15]Nociceptin
CAS :<p>Potent NOP agonist (EC50 = 1 nM), >875x selective vs opioid receptors; outperforms nociceptin in vivo, increases pain perception, reduces movement.</p>Formule :C82H137N31O22Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1909.18ICI 174,864
CAS :<p>Selective δ opioid antagonist. Exhibits partial agonist in vitro activity at δ receptors at high concentrations.</p>Formule :C38H53N5O7Degré de pureté :98%Couleur et forme :White SolidMasse moléculaire :691.87TRV056
CAS :<p>TRV056 is a Gq-biased AT1R agonist effective in Gq-mediated signaling and a basis for similar drug development.</p>Formule :C52H74N14O13Couleur et forme :SolidMasse moléculaire :1103.249Helianorphin-19
<p>Helianorphin-19: Potent KOR agonist (Ki=25 nM; EC50=45 nM), 200x selective over μ/δ receptors, effective in mouse pain model, non-sedative.</p>Couleur et forme :LiquidGluten Exorphin B5
CAS :<p>Gluten exorphin B5 (GE-B5) is a food-derived opioid peptide identified in digests of wheat gluten.</p>Formule :C30H38N6O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :594.66Axelopran
CAS :<p>Axelopran (TD-1211) treats opioid constipation; it's a potent, selective peripheral opioid blocker.</p>Formule :C26H39N3O4Couleur et forme :SolidMasse moléculaire :457.61LO-4-25
<p>LO-4-25 is a covalent degrader targeting the androgen receptor (AR) and its splice variant AR-V7. It covalently binds to the E3 ubiquitin ligase CUL4 DCAF16, facilitating the ubiquitination of both AR and AR-V7, which are then recognized and degraded by the proteasome, leading to reduced protein levels of AR and AR-V7 in cells. LO-4-25 is promising for research on androgen-independent prostate cancer.</p>Couleur et forme :Odour SolidHemorphin-7
CAS :<p>Hemorphin-7, an atypical opioid peptide from hemoglobin, may enhance memory, promote cell growth, and is a potential breast cancer biomarker.</p>Formule :C49H64N12O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :997.11[DAla2, DArg6] Dynorphin A, (1-13) (porcine)
CAS :'[DAla2, DArg6] Dynorphin A (1-13) porcine is a potent opioid peptide resistant to enzymatic degradation.'Formule :C76H128N24O15Couleur et forme :SolidMasse moléculaire :1617.98Dipropyl phthalate
CAS :<p>Dipropyl phthalate is a weak androgen receptor inhibitor, and can be used in biochemical experiments and drug synthesis.</p>Formule :C14H18O4Degré de pureté :98.62%Couleur et forme :SolidMasse moléculaire :250.29Cgp 29287
CAS :<p>Cgp 29287 is a primate-specific renin inhibitor. It also has a prolonged duration of action.</p>Formule :C72H110N20O15Couleur et forme :SolidMasse moléculaire :1495.77BAY 1003803
CAS :<p>BAY 1003803 is a glucocorticoid receptor agonist for the topical treatment of psoriasis or severe atopic dermatitis.</p>Formule :C21H18ClF5N2O4Couleur et forme :SolidMasse moléculaire :492.83SL910102
CAS :<p>SL910102 is a nonpeptide angiotensin antagonist of the AT1 receptor.</p>Formule :C30H30N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :490.60β-Naltrexamine dihydrochloride
CAS :<p>β-Naltrexamine dihydrochloride is an orally administered, irreversible opioid receptor antagonist. Its derivatives exhibit optimised subtype selectivity and can be used for pain research.</p>Formule :C20H28Cl2N2O3Degré de pureté :95.98%Couleur et forme :SoildMasse moléculaire :415.35Neuropeptide EI, rat
CAS :<p>Displays functional MCH-antagonist and MSH-agonist activity in different behavioral paradigms.</p>Formule :C63H98N16O23Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1447.55(N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8)
CAS :<p>E-2078, known chemically as (N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8), is a stable analog of Dynorphin A (1–8) and functions as a kappa opioid</p>Formule :C50H81N15O9Couleur et forme :SolidMasse moléculaire :1036.27Gridegalutamide
CAS :<p>Gridegalutamide exhibits anti-androgen and anti-tumor activities.</p>Formule :C41H45F3N8O5SCouleur et forme :SolidMasse moléculaire :818.91Kylo-0603
CAS :<p>KYLO-0603 is an orally active and selective THR-β agonist with an EC50 of 31.07 nM. It effectively reduces serum cholesterol and low-density lipoprotein cholesterol levels. By activating THR-β receptors, KYLO-0603 enhances the expression of THR-regulated genes like iodothyronine deiodinase 1 (Dio1), malic enzyme 1 (Me1), and thyroid hormone-responsive (Thrsp) gene, while it inhibits the expression of inflammatory and fibrosis-related genes, including low-density lipoprotein receptor (LDL-R) gene. This compound is applicable for the study of metabolic associated steatohepatitis (MASH) and liver fibrosis.</p>Formule :C81H134N8O28Couleur et forme :SolidMasse moléculaire :1667.97WAY267464 HCl
CAS :<p>WAY267464: nonpeptide OT agonist, anxiolytic, modulates selectivity, improves CNS entry and oral uptake.</p>Formule :C32H37Cl2N7O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :654.59Dynorphin B (1-13) (TFA)
<p>Dynorphin B (1-13) TFA acts as an agonist on opioid κ-receptor .</p>Formule :C76H116N21F3O19Couleur et forme :SolidMasse moléculaire :1684.86A 779
CAS :<p>A 779 is a potent antagonist of the G-protein-coupled receptor Mas, the Ang1-7 receptor, which is distinct from conventional AngII.</p>Formule :C39H60N12O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :872.973-Cl-Pyridine-amide-acrylaldehyde-piperazine
<p>3-Cl-Pyridine-amide-acrylaldehyde-piperazine serves as a synthetic intermediate for LO-4-25. LO-4-25 is a ligand for the androgen receptor (AR) DNA binding domain and is linked to a truncated fumaramide handle via a connector. In 22Rv1 cells, LO-4-25 demonstrates potent degradation of both AR and AR-V7.</p>Couleur et forme :Odour SolidAntihypertensive agent 2
<p>Antihypertensive agent 2 (Compound 4g) exhibits effective antagonistic activities against angiotensin II receptor 1 and reduces blood pressure with equal or</p>Formule :C22H15NO3Couleur et forme :SolidMasse moléculaire :341.36Antihypertensive agent 3
<p>Antihypertensive agent 3 (compound 4a), an angiotensin II receptor 1 antagonist, demonstrates antihypertensive activity in spontaneously hypertensive rats (SHRs</p>Formule :C16H13NO4SCouleur et forme :SolidMasse moléculaire :315.34
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