NF-κB
Le facteur nucléaire kappa B (NF-κB) est un facteur de transcription qui régule l'expression des gènes impliqués dans les réponses immunitaires, l'inflammation, la survie cellulaire et la prolifération. Le NF-κB est activé en réponse à divers stimuli, y compris les cytokines, les agents pathogènes et les signaux de stress. La dérégulation de la signalisation du NF-κB est associée à des maladies inflammatoires chroniques, au cancer et aux troubles auto-immuns. Chez CymitQuimica, nous offrons une sélection complète de modulateurs de la voie NF-κB pour soutenir vos recherches en inflammation, oncologie et régulation immunitaire.
445 produits trouvés pour "NF-κB"
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Flaconitine
CAS :<p>Flaconitine (Acetylaconitine) is an NF-κB inhibitor and an alkaloid.</p>Formule :C36H49NO12Degré de pureté :98% - 99.84%Couleur et forme :SolidMasse moléculaire :687.77Vanillic Acid
CAS :<p>Vanillic Acid (Acide vanillique) is used as a condiment in food, which used in wine. It is an intermediate in the production of vanillin from ferulic acid.</p>Formule :C8H8O4Degré de pureté :99.82%Couleur et forme :White Odourless Crystals Or PowderMasse moléculaire :168.152-AMINO-5-PHENYL-THIOPHENE-3-CARBOXYLIC
CAS :<p>2-AMINO-5-PHENYL-THIOPHENE-3-CARBOXYLIC is Inhibitior of IKKβ.</p>Formule :C11H10N2OSDegré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :218.27BOT-64
CAS :<p>BOT-64 is an IKK-2 inhibitor which targets the Ser177 and/or Ser181 residues in the kinase's activation loop domain.BOT-64 is a cell-permeable benzoxathiole</p>Formule :C15H15NO2SDegré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :273.3518α-Glycyrrhetinic acid
CAS :<p>18α-Glycyrrhetinic acid (Enoxolone) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid.</p>Formule :C30H46O4Degré de pureté :98.54% - 99.68%Couleur et forme :SolidMasse moléculaire :470.68(E/Z)-IT-603
CAS :<p>(E/Z)-IT-603 is a cell-permeable c-Rel inhibitor. IT-603 directly and reversibly binds to c-Rel to change its conformation and blocks its DNA binding activity.</p>Formule :C11H9BrN2O3SDegré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :329.17Ginsenoside Rk3
CAS :<p>Ginsenosides Rk3 & Rh4 may treat inflammation and ischemic heart disease.</p>Formule :C36H60O8Degré de pureté :99.33% - 99.88%Couleur et forme :SolidMasse moléculaire :620.86Asperulosidic acid
CAS :<p>Asperulosidic acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities. ASPA is related to the inhibition of inflammatory cytokines.</p>Formule :C18H24O12Degré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :432.38BX795
CAS :<p>BX795 selectively inhibits PDK1 (IC50: 6 nM), 140x over PKA, 1600x over PKC, 100x over GSK3β in cell-free assays.</p>Formule :C23H26IN7O2SDegré de pureté :98% - 99.57%Couleur et forme :SolidMasse moléculaire :591.47Galloylpaeoniflorin
CAS :<p>Galloylpaeoniflorin (6'-O-Galloyl paeoniflorin) may be developed as a cytoprotector against ROS-mediated oxidative stress.</p>Formule :C30H32O15Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :632.57AS-2444697
CAS :<p>AS-2444697, an IRAK-4 inhibitor (C50=21 nM), offers renal protection via anti-inflammatory effects on human and rat IRAK-4.</p>Formule :C19H21ClN6O4Degré de pureté :97.17%Couleur et forme :SolidMasse moléculaire :432.86AZD3264
CAS :<p>AZD3264 is a new type IKK2 inhibitor.</p>Formule :C21H23N5O4SDegré de pureté :98.98% - 99.17%Couleur et forme :SolidMasse moléculaire :441.5IRAK4-IN-7
CAS :<p>IRAK4-IN-7 (CA-4948) is a selective and potent IRAK4 kinase inhibitor with in vivo activity in a TLR4-induced cytokine release model.</p>Formule :C21H19N7O3Degré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :417.42SC-514
CAS :<p>SC-514 (GK 01140) is a selective, orally active, ATP-competitive IKK-2 inhibitor (IC50=11.2±4.7 μM), obstructs NF-κB-dependent gene expression.</p>Formule :C9H8N2OS2Degré de pureté :99.88% - >99.99%Couleur et forme :SolidMasse moléculaire :224.3Cyclo(his-pro)
CAS :<p>Cyclo(his-pro) is a cyclic dipeptide that shields against oxidative damage by activating Nrf2.</p>Formule :C11H14N4O2Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :234.25Astaxanthin
CAS :<p>Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.</p>Formule :C40H52O4Degré de pureté :95.1% - 99.79%Couleur et forme :Needles From Acetone/Light Petroleum SolidMasse moléculaire :596.847,4'-Dihydroxyflavone
CAS :<p>7,4'-Dihydroxyflavone (4',7-Dihydroxyflavone) can induce transcription of nodulation (nod) genes in Rhizobium meliloti.</p>Formule :C15H10O4Degré de pureté :99.39% - 99.6%Couleur et forme :SolidMasse moléculaire :254.24Rucaparib
CAS :<p>Rucaparib (PF-01367338) is a orally PARP inhibitor and a H6PD inhibitor. Rucaparib exhibits antitumor activity against CRPC. Cost-effective and quality-assured.</p>Formule :C19H18FN3ODegré de pureté :98.24% - 99.80%Couleur et forme :SolidMasse moléculaire :323.36Avicularin
CAS :<p>Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.</p>Formule :C20H18O11Degré de pureté :97.02% - 99.94%Couleur et forme :White PowderMasse moléculaire :434.35Berbamine
CAS :<p>Berbamine is a natural product extracted from Phellodendron amurense.</p>Formule :C37H40N2O6Degré de pureté :98.92% - 99.67%Couleur et forme :White Crystal PowderMasse moléculaire :608.72Tizoxanide
CAS :<p>Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine.</p>Formule :C10H7N3O4SDegré de pureté :98.89% - 99.28%Couleur et forme :SolidMasse moléculaire :265.25Micheliolide
CAS :<p>Micheliolide(MCL) is a sesquiterpene lactone which inhibits various inflammatory response.</p>Formule :C15H20O3Degré de pureté :98% - 99.37%Couleur et forme :SolidMasse moléculaire :248.32Ginsenoside Rb3
CAS :<p>Ginsenoside Rb3 (Gypenoside IV) is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB transcriptional activity.</p>Formule :C53H90O22Degré de pureté :98% - 99.98%Couleur et forme :SolidMasse moléculaire :1079.27Chelidonic acid
CAS :<p>Chelidonic acid, in Chelidonium majus, acts as an analgesic, antimicrobial, CNS sedative, and has anti-inflammatory properties.</p>Formule :C7H4O6Degré de pureté :99.03%Couleur et forme :SolidMasse moléculaire :184.1Ac2-26 acetate
<p>Ac2-26 acetate is an active N-terminal peptide of annexin A1(AnxA1).</p>Formule :C141H210N32O44SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :3089.43Rhoifolin
CAS :<p>Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.</p>Formule :C27H30O14Degré de pureté :98.11% - 98.58%Couleur et forme :SolidMasse moléculaire :578.52Isoquercetin
CAS :<p>1.</p>Formule :C21H20O12Degré de pureté :98.08% - 99.76%Couleur et forme :SolidMasse moléculaire :464.38Muscone
CAS :<p>Muscone (3-Methylcyclopentadecanone) is an organic compound that is the primary contributor to the odor of musk.</p>Formule :C16H30ODegré de pureté :98.97% - ≥98%Couleur et forme :Colourless Liquid LiquidMasse moléculaire :238.41Eclitasertib
CAS :<p>Eclitasertib is a potent inhibitor of receptor-interacting protein kinase 1 (RIPK1, IC50 of <1 µΜ).</p>Formule :C19H18N6O3Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :378.38Sodium Aescinate
CAS :<p>Sodium Aescinate (Escin sodium salt) is extracted from Aesculus wilsonii.</p>Formule :C54H83NaO23Degré de pureté :95.17%Couleur et forme :SolidMasse moléculaire :1123.21Ginsenoside Rd
CAS :<p>Ginsenoside Rd (Gypenoside VIII) may have properties that inhibit or prevent the growth of tumors.</p>Formule :C48H82O18Degré de pureté :99.13% - 99.92%Couleur et forme :SolidMasse moléculaire :947.15WITHAFERIN A
CAS :<p>WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/</p>Formule :C28H38O6Degré de pureté :97.41% - 99.99%Couleur et forme :SolidMasse moléculaire :470.6Dehydroevodiamine
CAS :<p>Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant</p>Formule :C19H15N3ODegré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :301.34Diethylmaleate
CAS :<p>Diethylmaleate (Maleic acid, diethyl ester) is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB.</p>Formule :C8H12O4Degré de pureté :98%Couleur et forme :Colourless LiquidMasse moléculaire :172.18Sinomenine
CAS :<p>Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.</p>Formule :C19H23NO4Degré de pureté :99.02% - 99.73%Couleur et forme :White PowderMasse moléculaire :329.392-Hydroxychalcone
CAS :<p>2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated. It inhibits invasion of breast cancer cells.</p>Formule :C15H12O2Degré de pureté :99.6%Couleur et forme :SolidMasse moléculaire :224.252,5-Dihydroxyacetophenone
CAS :<p>2,5-Dihydroxyacetophenone has anti-anxiety, neuroprotective, anti-inflammatory properties, and modulates cell signaling and melanogenesis.</p>Formule :C8H8O3Degré de pureté :99.75%Couleur et forme :Yellow PowderMasse moléculaire :152.15Dauricine
CAS :<p>1.</p>Formule :C38H44N2O6Degré de pureté :99.24% - 99.75%Couleur et forme :White PowderMasse moléculaire :624.77Dendrophenol
CAS :<p>Dendrophenol (Moscatilin) is a natural product isolated from the stem of Dendrobium loddigesii Rolfe, act as a NF-κB inhibitor. Antineoplastic activity.</p>Formule :C17H20O5Degré de pureté :98.2% - 99.36%Couleur et forme :SolidMasse moléculaire :304.34GSK8612
CAS :<p>GSK8612 is a highly selective and potent inhibitor of Tank-binding Kinase-1 (TBK1, pIC50: 6.8) .</p>Formule :C17H17BrF3N7O2SDegré de pureté :99.46% - 99.8%Couleur et forme :SolidMasse moléculaire :520.33IRAK inhibitor 6
CAS :<p>IRAK inhibitor 6 is an inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK-4, IC50: 160 nM).</p>Formule :C20H20N4O3SDegré de pureté :99.44%Couleur et forme :SolidMasse moléculaire :396.46Phellodendrine
CAS :<p>Phellodendrine may treat nephritis by blocking macrophage and T cell activity in glomeruli.</p>Formule :C20H24NO4Degré de pureté :98.7% - 99.94%Couleur et forme :SolidMasse moléculaire :342.41yangonin
CAS :<p>Yangonin (Y100550) is a novel CB1 receptor ligand with affinity for human recombinant CB1 receptors.</p>Formule :C15H14O4Degré de pureté :98.82% - 99.55%Couleur et forme :Pale Yellow PowderMasse moléculaire :258.27Iron sucrose
CAS :<p>Iron sucrose (Sucroferric oxyhydroxide) is treatment of iron deficiency anemia.</p>Formule :C18H24Fe2O24Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :736.1Isovitexin
CAS :<p>1.</p>Formule :C21H20O10Degré de pureté :99.79% - 99.97%Couleur et forme :SolidMasse moléculaire :432.38Neochlorogenic acid
CAS :<p>Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.</p>Formule :C16H18O9Degré de pureté :99.12% - 99.54%Couleur et forme :White PowderMasse moléculaire :354.31Denosumab
CAS :<p>Denosumab is a monoclonal antibody given subcutaneously that inhibits osteoclast activity by targeting the RANK ligand</p>Formule :C6404H9912N1724O2004S50Degré de pureté :95.9% (SDS-PAGE); 98.4% (SEC-HPLC) - 99.90%Couleur et forme :LiquidMasse moléculaire :144.71 kDaTriacetylresveratrol
CAS :<p>Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity, it inhibits the phosphorylation of STAT3 and NFκB in pancreatic cancer cells.</p>Formule :C20H18O6Degré de pureté :99.81%Couleur et forme :Off White PowderMasse moléculaire :354.35IMD-0354
CAS :<p>IMD-0354 (IKK2 Inhibitor V) is an IKKβ inhibitor and inhibits IκBα phosphorylation in NF-κB pathway.</p>Formule :C15H8ClF6NO2Degré de pureté :99.65% - 99.98%Couleur et forme :SolidMasse moléculaire :383.67Necrostatin-34
CAS :<p>Necrostatin-34 (2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4) is a RIPK1 kinase inhibitor, stabilizing RIPK1 kinase in an inactive conformation by occupying a</p>Formule :C18H16N4O2S2Degré de pureté :98.66% - 98.8%Couleur et forme :SolidMasse moléculaire :384.48
