MAPK
Les MAPK sont une famille de kinases protéiques impliquées dans une variété de processus cellulaires, y compris la croissance, la prolifération, la différenciation et les réponses au stress. La voie de signalisation MAPK comprend plusieurs niveaux, y compris ERK, JNK et p38 MAPK, chacun jouant des rôles distincts dans la fonction cellulaire. La dérégulation de la signalisation MAPK est liée au cancer, aux maladies inflammatoires et aux troubles métaboliques. Chez CymitQuimica, nous offrons un large éventail d'inhibiteurs et d'activateurs de MAPK pour soutenir vos recherches en biologie cellulaire, transduction de signaux et mécanismes des maladies.
924 produits trouvés pour "MAPK".
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SU3327
CAS :SU3327 (halicin) is a potent, selective and substrate-competitive inhibitor of JNK(IC50 of 0.7 μM).Formule :C5H3N5O2S3Degré de pureté :98.39%Couleur et forme :SolidMasse moléculaire :261.3BAY 2965501
CAS :BAY 2965501 is a potent and selective diacylglycerol kinase zeta (DGKζ) inhibitor that induces pERK activation.BAY 2965501 can be used in the study of cancer.Formule :C20H19FN4O3SDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :414.453ETC-206
CAS :ETC-206 is a selective inhibitor of MNK1 and MNK2 (IC50s: 64 nM and 86 nM).Formule :C25H20N4O2Degré de pureté :99.72% - 99.79%Couleur et forme :SolidMasse moléculaire :408.4519B-Raf IN 2
CAS :B-Raf IN 2, compound Ia, is a highly effective and specific inhibitor of BRAF. It exhibits significant potential for cancer research.Formule :C20H17F2N5O4SDegré de pureté :98.86%Couleur et forme :White SolidMasse moléculaire :461.44MRTX0902
CAS :MRTX0902 is an effective and high selective inhibitor of SOS1 with an IC50 of 46 nM and a Ki of 2 nM.Formule :C22H24N6ODegré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :388.47ERK5-IN-6
CAS :ERK5-IN-6 is an ERK5 kinase inhibitor with antiproliferative, anticonvulsant, and antitumor activity for the study of central nervous system related diseases.Formule :C23H21N3Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :339.43(R)-Ketorolac
CAS :(R)-Ketorolac ((+)-Ketorolac) is the R-enantiomer of Ketorolac, with potent analgesic activity.Formule :C15H13NO3Degré de pureté :99.55%Couleur et forme :White SolidMasse moléculaire :255.2686MAP4K4-IN-3
CAS :MAP4K4-IN-3 (Compound 17) may be a viable target for antidiabetic agents, a serine/threonine protein kinase.Formule :C15H12ClN5Degré de pureté :98.07%Couleur et forme :White SolidMasse moléculaire :297.742CC-90003
CAS :CC-90003 is a selective inhibitor of ERK 1/2. It has antitumor activity.Formule :C22H21F3N6O2Degré de pureté :99.42%Couleur et forme :SolidMasse moléculaire :458.4363LUT014
CAS :LUT014 is a B-Raf inhibitor (IC50: 11.7 nM) and developed to decrease dose-limiting acneiform lesions associated with EGFR Inhibitors treatment.Formule :C27H19F3N8ODegré de pureté :99.03%Couleur et forme :Yellow SolidMasse moléculaire :528.488BAS 00489700
CAS :BAS 00489700 is a N-UTR interaction inhibitor. BAS 00489700 inhibits virus replication in cell culture.Formule :C19H16N2O4Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :336.3413RAS GTPase inhibitor 1
CAS :RAS GTPase inhibitor 1 Free Base is a highly potent RAS GTPase inhibitor with antitumor activity.Formule :C25H27ClFN5Couleur et forme :White SolidMasse moléculaire :451.97ASP6918
ASP6918 is a potent, orally active KRAS G12C inhibitor with an IC50 of 0.028 µM. It inhibits cell growth and demonstrates antitumor activity.Formule :C36H43N7O3Couleur et forme :SolidMasse moléculaire :621.34274Kinase Inhibitor Library
A unique collection of xnum kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;Couleur et forme :Odour SolidBChE/p38-α MAPK-IN-2
BChE/p38-α MAPK-IN-2 is a dual inhibitor of BChE and p38-α MAPK. It has an IC50 of 5.1 nM for hBChE and exhibits a 1000-fold selectivity over hAChE. Its IC50 for p38α MAPK is 8.12 μM. BChE/p38-α MAPK-IN-2 demonstrates neuroprotective properties, making it useful for research on neurological disorders such as Alzheimer's disease.Antimicrobial agent-21
CAS :Antimicrobial agent-21 is a potent mitogen activated protein kinase inhibitor with antibacterial, anti-inflammatory and antitumor activity for the treatment ofFormule :C18H13N3OSDegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :319.38PROTAC ERK5 degrader-1
CAS :PROTACERK5 degrader-1 (compound 2) is a bifunctional ERK5 PROTAC degrader. It induces the degradation of ERK5 in MOLT-4 cells via a VHL-mediated proteasome pathway. PROTACERK5 degrader-1 is useful for studying diseases or disorders characterized by abnormal ERK5 activity.Formule :C54H67F3N10O6SCouleur et forme :SolidMasse moléculaire :1041.23Klotho-derived peptide 1 hydrochloride
Klotho-derived peptide 1 (KP1 human) hydrochloride inhibits the interaction between TGF-β and TGF-β receptor 2, suppressing the activation of TGF-β-induced Smad2/3 and mitogen-activated protein kinase (MAPK). Additionally, it exhibits antifibrotic and renal protective effects in mouse models.Couleur et forme :Odour SolidHRS 4642
CAS :HRS 4642 is a selective KRAS G12D inhibitor with a Kd value of 0.083 nM, antitumour, inhibits phosphorylation of downstream MEK and ERK proteins.Formule :C34H35F3N6O3Degré de pureté :99.17%Masse moléculaire :632.68GGDPS-IN-1
GGDPS-IN-1 (Compound 37) is an inhibitor of geranylgeranyl diphosphate synthase (GGDPS) with an IC50 of 49.4 nM, disrupting protein geranylgeranylation in myeloma cells.Formule :C15H28N4O6P2Couleur et forme :SolidMasse moléculaire :422.14841
