Ras
Les protéines Ras sont de petites GTPases qui agissent comme des commutateurs moléculaires dans la voie de signalisation MAPK, contrôlant la croissance, la différenciation et la survie cellulaires. Ras activé initie une cascade de signalisation qui inclut Raf, MEK et ERK, conduisant à diverses réponses cellulaires. Les mutations des gènes Ras sont courantes dans les cancers, faisant de Ras un point focal important de la recherche sur le cancer. Chez CymitQuimica, nous offrons une gamme de modulateurs de Ras pour soutenir vos recherches en biologie du cancer, transduction de signaux et développement thérapeutique.
167 produits trouvés pour "Ras".
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KRpep-2d
CAS :KRpep-2d, a potent inhibitor of K-Ras, effectively suppresses the proliferation of cancer cells driven by K-Ras.Formule :C109H183N43O25S2Couleur et forme :SolidMasse moléculaire :2560.02TAT-PAK18 R192A
TAT-PAK18 R192A is an inactive Tat-Pak peptide. It does not influence Rac1 translocation triggered by any tested proteins.Formule :C143H247N55O37Masse moléculaire :3326.91369pan-KRAS-IN-8
pan-KRAS-IN-8 (Compound 38) is an inhibitor of the human tumor mutated gene KRAS. It effectively suppresses the proliferation of KRAS mutant cells AsPC-1 (G12D mutant) and SW480 (G12V mutant), with IC50 values of 0.07 nM and 0.18 nM, respectively.Formule :C48H61N7O7SMasse moléculaire :879.43532(RS)-G12Di-1
(RS)-G12Di-1 is a selective covalent inhibitor of K-Ras-G12D.Formule :C37H35FN6O4Couleur et forme :SolidMasse moléculaire :646.27038GGTI298 Trifluoroacetate
CAS :GGTI298 trifluoroacetate (GGTI298TFA salt) is a geranylgeranyltransferase I inhibitor that causes cell cycle arrest and induces apoptosis.Formule :C27H33N3O3S·C2HF3O2Degré de pureté :98.07% - >99.99%Couleur et forme :SolidMasse moléculaire :593.66AM-001
CAS :AM-001 is a non-competitive Epac1 inhibitor that blocks Rap1 activation and is used in heart disease research.Formule :C24H16FN3OS2Degré de pureté :99.92%Couleur et forme :Yellow SolidMasse moléculaire :445.53KRASG12C IN-14
KRASG12C IN-14 (compound 15), a potent inhibitor specifically designed for the KRAS G12C mutation, exhibits impressive efficacy in impeding CYPA-dependent KRAS-BRAF interaction and ERK phosphorylation in NCI-H358 cells, both with an IC 50 of 0.002 μM.Formule :C51H65F4N9O9S2Couleur et forme :SolidMasse moléculaire :1088.24MRTF-A-IN-1
MRTF-A-IN-1 (compound 14) is an inhibitor of MRTF-A. It effectively suppresses cell proliferation and induces senescence in HCC cells.Formule :C22H21N3Couleur et forme :SolidMasse moléculaire :327.42MC 976
CAS :MC 976 is a derivative of Vitamin D3.Formule :C27H42O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :414.63Ras Inhibitory Peptide acetate
Ras Inhibitory Peptide acetate, involved in cancer-related Ras signaling.Formule :C55H95N19O13Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :1230.46MRTF-A-IN-2
MRTF-A-IN-2 (compound 16) is an inhibitor of MRTF-A. It effectively suppresses cell proliferation and induces senescence in HCC cells.Couleur et forme :Odour SolidGGDPS-IN-1
GGDPS-IN-1 (Compound 37) is an inhibitor of geranylgeranyl diphosphate synthase (GGDPS) with an IC50 of 49.4 nM, disrupting protein geranylgeranylation in myeloma cells.Formule :C15H28N4O6P2Couleur et forme :SolidMasse moléculaire :422.14841Rac1 Inhibitor F56, control peptide TFA
Rac1 Inhibitor F56, control peptide TFA, is a peptide containing Rac1 residues 45-60. It features a mutation from Trp56 to Phe56. This inhibitor does not affect the interaction between Rac1 and guanine nucleotide exchange factors (GEFs).Formule :C72H116N18O23S·xC2HF3O2MAPK Inhibitor Library
A unique collection of xnum cancer cell differentiation inducing compounds for high throughput and high content screening;Couleur et forme :Odour SolidRef: TM-L1400
1mgÀ demander10μL*10mM (DMSO)À demander20μL*10mM (DMSO)À demander30μL*10mM (DMSO)À demander50μL*10mM (DMSO)À demander100μL*10mM (DMSO)À demander250μL*10mM (DMSO)À demanderAnticancer agent 207
Anticanceragent 207 (compound 10b) is an effective anticancer agent. It binds to NRAS rG4 with a KD value of 2.31 µM. It exhibits cytotoxicity and reduces NRAS protein expression, demonstrating antitumor activity.Formule :C29H39FN4O2Masse moléculaire :494.30576-Thio-GTP tetrasodium
6-Thio-GTP (tetrasodium) is an inhibitor of Vav1-Rac. It can suppress TCR-induced T cell proliferation and CD28-mediated T cell survival. In a murine model of allogeneic heart transplantation, 6-Thio-GTP (tetrasodium) demonstrates immunosuppressive effects, which can prolong the survival time of heart transplants.Formule :C10H12N5Na4O13P3SCouleur et forme :SolidMasse moléculaire :626.89559(±)5(6)-DiHETE lactone
CAS :(±)5(6)-DiHETE lactone is a 1,5-lactone, specific quantification of (±)5(6)-DiHETE in biological samples.Formule :C20H32O3Couleur et forme :Transparent LiquidMasse moléculaire :320.47RAS GTPase inhibitor 1
CAS :RAS GTPase inhibitor 1 Free Base is a highly potent RAS GTPase inhibitor with antitumor activity.Formule :C25H27ClFN5Couleur et forme :White SolidMasse moléculaire :451.97KRpep-2d TFA
KRpep-2d (TFA) is a potent inhibitor of K-Ras, effectively hindering the proliferation of K-Ras-driven cancer cells, thereby serving as a valuable asset forFormule :C110H183F3N44O27S2Couleur et forme :SolidMasse moléculaire :2675.03Goralatide
CAS :Goralatide, isolated from fetal calf bone marrow, exerts a high inhibitory activity on the proliferation of hematopoietic pluripotent stem cells.Formule :C20H33N5O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :487.5
