ERK
205 produits trouvés pour "ERK"
Rineterkib
CAS :Rineterkib (ERK-IN-1) is an inhibitor of RAF and ERK1/2 activating mutations in the MAPK pathway.Formule :C26H27BrF3N5O2Degré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :578.42Ref: TM-T11224
1mg87,00€5mg170,00€10mg318,00€25mg538,00€50mg765,00€100mg1.035,00€1mL*10mM (DMSO)224,00€Ravoxertinib hydrochloride
CAS :Ravoxertinib hydrochloride is an orally bioavailable and selective inhibitor for ERK kinase activity (IC50: 6.1 nM and 3.1 nM for ERK1 and ERK2, respectively).Formule :C21H19Cl2FN6O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :477.32Omtriptolide
CAS :Omtriptolide, triptolide purified from the Chinese herb, is a water-soluble derivative prodrug.Formule :C24H28O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :460.479Pamoic acid
CAS :Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.
Formule :C23H16O6Degré de pureté :99.99%Couleur et forme :Fine Yellow PowderMasse moléculaire :388.37WQ-C-401
CAS :WQ-C-401 is an orally active inhibitor of the platelet-derived growth factor receptor (PDGFR). It inhibits cell proliferation by blocking PDGFR auto-phosphorylation in a concentration-dependent manner, with EC50 values of 3.5 nM for PDGFRαY849 and 5.8 nM for PDGFRβY1021. Additionally, WQ-C-401 suppresses the proliferation and migration of PASMCs by inhibiting PDGF-BB-induced phosphorylation of ERK1/2, reduces collagen I synthesis, and increases α-SMA expression, thereby preventing pulmonary vascular remodeling. This compound shows promise for research in the field of pulmonary arterial hypertension.
Formule :C24H26N4O3Couleur et forme :SolidMasse moléculaire :418.49
