Canal TRP/TRPV
Les canaux TRP (récepteur potentiel transitoire), y compris la sous-famille TRPV, sont un groupe de canaux ioniques impliqués dans divers processus sensoriels, tels que la sensation de température, la perception de la douleur et l'osmorégulation. Les canaux TRP sont largement exprimés dans différents tissus et jouent un rôle dans les réponses physiologiques aux stimuli environnementaux. Les canaux TRPV, en particulier, sont impliqués dans la détection des changements de température et sont associés à des conditions telles que la douleur chronique, l'inflammation et le cancer. Chez CymitQuimica, nous proposons une gamme complète de modulateurs de canaux TRP/TRPV pour soutenir vos recherches en biologie sensorielle, gestion de la douleur et transduction du signal.
95 produits trouvés pour "Canal TRP/TRPV"
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GFB-8438
CAS :GFB-8438 is a potent and subtype selective inhibitor of TRPC5(IC50s of 0.18 and 0.29 μM of hTRPC5 and hTRPC4, respectively).Formule :C16H14ClF3N4O2Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :386.76Ref: TM-T11394
2mg34,00€5mg50,00€1mL*10mM (DMSO)55,00€10mg77,00€25mg111,00€50mg166,00€100mg236,00€200mg349,00€IA-Alkyne
CAS :IA-Alkyne: TRPC agonist, cysteine-reactivity probe, potential in respiratory infection study.Formule :C8H12INODegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :265.09Ref: TM-T15543
1mg56,00€1mL*10mM (DMSO)114,00€5mg119,00€10mg177,00€25mg250,00€50mg313,00€100mg432,00€TRPV4 agonist-1 free base
CAS :TRPV4 agonist-1 free base (OUN67600) is an agonist of transient receptor potential vanilloid 4 (TRPV4;EC50 of 60 nM, in the hTRPV4 Ca2+ assay).Formule :C25H22F2N4O2Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :448.46Vocacapsaicin hydrochloride
CAS :Vocacapsaicin hydrochloride (CA-008 hydrochloride) is a non-opioid TRPV1 agonist, a raw material for capsaicin, and is used for pain relief.Formule :C26H42ClN3O4Degré de pureté :99.66% - 99.80%Couleur et forme :SolidMasse moléculaire :496.08BI-749327
CAS :BI-749327 is a high selectivity and orally bioavailable antagonist of TRPC6 (IC50s: 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6).Formule :C23H21F3N4O2Degré de pureté :99.68% - 99.84%Couleur et forme :SolidMasse moléculaire :442.43Ref: TM-T10537
1mg126,00€2mg168,00€5mg260,00€1mL*10mM (DMSO)285,00€10mg409,00€25mg597,00€50mg782,00€100mg1.044,00€500mg2.088,00€CBP-1008
CBP-1008 is a dual-ligand peptide-drug conjugate (PDC) with MMAE, targeting folate receptor (FRα) and TRPV6. It exhibits high binding affinity to FRα and low affinity to TRPV6. CBP-1008 shows antitumor activity and can be utilized for research in advanced solid tumors such as colorectal cancer, breast cancer, non-small cell lung cancer, ovarian cancer, adrenocortical carcinoma, and follicular dendritic cell sarcoma.Couleur et forme :Odour Solid(S)-ABT 102
CAS :N-[(1S)-1H-inden-1-yl]-N'-indazol-4-ylurea is a strong TRPV1 blocker with a 123 nM IC50 against capsaicin.Formule :C21H24N4ODegré de pureté :99.65% - 99.77%Couleur et forme :SoildMasse moléculaire :348.44Ref: TM-T29522L
1mg73,00€5mg149,00€1mL*10mM (DMSO)154,00€10mg212,00€25mg319,00€50mg447,00€100mg610,00€200mg822,00€RN-1665
CAS :RN-1665 is a potent and selective TRPV4 receptor antagonist.Formule :C20H24F5N3O3S2Degré de pureté :99.96%Couleur et forme :SoildMasse moléculaire :513.54Cyclic ADP-Ribose (ammonium salt)
Cyclic ADP-Ribose (ammonium salt) (cADPR) is an NAD⁺ metabolite that triggers Ca²⁺ release from ER stores via ryanodine receptors, relevant to inflammation research.Formule :C15H21N5O13P2·xNH3Couleur et forme :SolidResolvin D2
CAS :Resolvin D2 (RvD2) is a TRPV1 inhibitor and pro-ablative mediator with anti-inflammatory, anti-infective and pro-ablative effects.Formule :C22H32O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :376.49Oleoyl Serotonin
CAS :Oleoyl Serotonin is an antagonist of hTRPV1 with an IC50 of 2.57 μM.Formule :C28H44N2O2Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :440.66Ref: TM-T22124
5mg62,00€10mg87,00€1mL*10mM (DMSO)90,00€25mg173,00€50mg299,00€100mg520,00€500mg1.134,00€N-Oleoyl Valine Ammonium salt
N-Oleoyl Valine Ammonium salt is an N-acyl amide compound that is a TRPV3 antagonist and can be used to study inflammation.Formule :C23H46N2O3Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :398.62GSK2798745
CAS :GSK2798745 is an orally active transient receptor potential vanilloid 4 (TRPV4) ion channel blocker (IC50s: 1.8 and 1.6 nM for hTRPV4 and rTRPV4).Formule :C25H28N6O3Couleur et forme :SolidMasse moléculaire :460.53AP 18
CAS :AP-18 is a potent and selective TRPA1 inhibitor.Formule :C11H12ClNODegré de pureté :99.85% - 99.96%Couleur et forme :SolidMasse moléculaire :209.67Ref: TM-T21543
5mg46,00€1mL*10mM (DMSO)48,00€10mg66,00€25mg114,00€50mg177,00€100mg286,00€200mg425,00€L-R4W2
CAS :Vanilloid TRPV1 (VR1) receptor antagonist peptide (IC50 ~ 0.1 μM); blocks Ca2+ currents in dorsal root ganglion neurons. Analgesic in vivo.Formule :C46H71N21O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1014.2TRPA1-IN-2
CAS :TRPA1-IN-2 is a potent and orally active TRPA1 inhibitor with an IC50 value of 0.04 µM.TRPA1-IN-2 has anti-inflammatory activity.Formule :C24H25F3N4ODegré de pureté :98.93%Couleur et forme :SoildMasse moléculaire :442.48Ref: TM-T77511
1mg56,00€5mg129,00€1mL*10mM (DMSO)142,00€10mg188,00€25mg319,00€50mg447,00€100mg600,00€200mg807,00€PF-04745637
CAS :PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM[1].Formule :C27H32ClF3N2O2Degré de pureté :98.88% - 99.3%Couleur et forme :SolidMasse moléculaire :509Ref: TM-T64337
1mg73,00€5mg145,00€1mL*10mM (DMSO)163,00€10mg197,00€25mg333,00€50mg475,00€100mg655,00€200mg882,00€TRPM8 antagonist 3
CAS :TRPM8 antagonist 3 is a blocker of TRPM8 (IC50 = 11 nM).Formule :C13H12N2O4SDegré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :292.31NGD-8243
CAS :NGD-8243 (N-[4-(trifluoromethyl)phenyl]-7-[3-(trifluoromethyl)pyridin-2-yl]quinazolin-4-amine) is a TRPV1 inhibitor and can be used in studies for preventionFormule :C21H12F6N4Degré de pureté :95.26%Couleur et forme :SolidMasse moléculaire :434.34BTD
CAS :BTD is a TRPC5 activator that activates heteromeric channel complexes composed of TRPC5 and its closest relatives TRPC1 or TRPC4.Formule :C24H33N3O4SCouleur et forme :SolidMasse moléculaire :459.6Phenazopyridine
CAS :Phenazopyridine is an orally administered azo dye with local analgesic effects on urinary tract infections,. against SARM1 and TRPM8.Formule :C11H11N5Degré de pureté :99.98%Couleur et forme :SolidMasse moléculaire :213.24AC1903
CAS :AC1903 is a specific inhibitor of TRPC5 channel, and has been shown to suppress severe proteinuria and prevent podocyte loss.Formule :C19H17N3ODegré de pureté :98.45%Couleur et forme :SolidMasse moléculaire :303.36ICILIN
CAS :ICILIN (AG-3-5) is a synthetic TRPM8 ion channel super-agonist.Formule :C16H13N3O4Degré de pureté :98.45% - ≥95%Couleur et forme :Light Yellow SolidMasse moléculaire :311.29HC-067047
CAS :HC-067047 is a potent and selective TRPV4 antagonist.Also inhibits the endogenous TRPV4-mediated response to 4α-PDH .Formule :C26H28F3N3O2Degré de pureté :99.45% - 99.97%Couleur et forme :SolidMasse moléculaire :471.51AM-0902
CAS :AM-0902 is a potent and specific TRPA1 antagonist (IC50s: 71/131 nM for rTRPA1 and hTRPA1).Formule :C17H15ClN6O2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :370.79SB 452533
CAS :SB 452533 is an antagonist of the vanilloid receptor 1(pKb: 7.8).Formule :C18H22BrN3ODegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :376.29Ref: TM-T23322
2mg39,00€5mg60,00€1mL*10mM (DMSO)73,00€10mg92,00€25mg173,00€50mg269,00€100mg389,00€200mg555,00€Pico145
CAS :Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels.Formule :C23H20ClF3N4O5Degré de pureté :99.06%Couleur et forme :SolidMasse moléculaire :524.88Ref: TM-T16532
1mg70,00€5mg150,00€1mL*10mM (DMSO)167,00€10mg215,00€25mg358,00€50mg517,00€100mg707,00€200mg1.009,00€TRPM4-IN-1
CAS :TRPM4-IN-1 (4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid) is a potent and selective inhibitor of TRPM4 with an IC50 of 1.5 μM.Formule :C15H11Cl2NO4Degré de pureté :97.22%Couleur et forme :SolidMasse moléculaire :340.16TRPM8 antagonist 2
CAS :TRPM8 antagonist 2 is a potent and selective TRPM8 antagonist with an IC50 of 0.2 nM. TRPM8 antagonist 2 is used in the research of neuropathic pain syndromes.Formule :C26H26N2O2Degré de pureté :98.1%Couleur et forme :SolidMasse moléculaire :398.5Ref: TM-T5698
1mg34,00€5mg66,00€1mL*10mM (DMSO)73,00€10mg99,00€25mg167,00€50mg260,00€100mg416,00€200mg600,00€MK6-83
CAS :MK6-83 is the transient receptor potential channel ML3 agonist.Formule :C16H20N2O2S2Degré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :336.479-Phenanthrol
CAS :9-Phenanthrol is inhibitor of the transient receptor potential melastatin 4 (TRPM) channel, a Ca2+ -activated non-selective cation channel.Formule :C14H10ODegré de pureté :98.48%Couleur et forme :SolidMasse moléculaire :194.23TC-I2000
CAS :TC-I2000 is an TRPM8 channel blocker. Inhibits icilin-induced TRPM8 channel activation in rTRPM8-expressing CHO cells with IC50 of 53 nM.Formule :C23H18F4N2ODegré de pureté :99.778%Couleur et forme :SolidMasse moléculaire :414.4Ref: TM-T8449
1mL*10mM (DMSO)À demander5mg35,00€10mg50,00€25mg88,00€50mg119,00€100mg173,00€200mg259,00€AMTB hydrochloride
CAS :AMTB HCl: Novel TRPM8 blocker, relieves pain, treats urinary issues, moderates bladder reflexes in rats.Formule :C23H27ClN2O2SDegré de pureté :99.08%Couleur et forme :SolidMasse moléculaire :430.99Ref: TM-T19723
1mg34,00€5mg74,00€1mL*10mM (DMSO)87,00€10mg119,00€25mg250,00€50mg424,00€100mg627,00€200mg890,00€ML204 hydrochloride
CAS :ML204 hydrochloride (ML204 HCl) is a TRPC4/TRPC5 channel antagonist.Formule :C15H19ClN2Couleur et forme :SolidMasse moléculaire :262.78WS-12
CAS :WS-12 is a potent TRPM8 agonist that acts as a cooling agent (EC50 : 193 nM)Formule :C18H27NO2Degré de pureté :99.99%Couleur et forme :Whitish To White Solid CrystallineMasse moléculaire :289.41Pyr10
CAS :Pyr10, a pyrazole derivative, selectively inhibits TRPC3, not STIM1/Orai1, with IC50 of 0.72 μM in TRPC3-HEK293, and 13.08 μM in BRL-2H3 cells.Formule :C18H13F6N3O2SDegré de pureté :99.69% - 99.7%Couleur et forme :SolidMasse moléculaire :449.37PF-4840154
CAS :PF-4840154: potent TrpA1 agonist; EC50 of 97 nM (rat) & 23 nM (human); triggers nociception in mice.
Formule :C26H38N6O2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :466.62Vanilloid receptor antagonist 1
CAS :Vanilloid receptor antagonist 1 (4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile) is a potent vanilloid receptor TRPV1 antagonist.Formule :C18H15N3O2Degré de pureté :98.14%Couleur et forme :SolidMasse moléculaire :305.33AMG9810
CAS :AMG 9810 blocks capsaicin's action on TRPV1; human IC50=24.5 nM, rat IC50=85.6 nM.Formule :C21H23NO3Degré de pureté :99.79% - 99.95%Couleur et forme :SolidMasse moléculaire :337.41Ref: TM-T7189
2mg34,00€5mg48,00€1mL*10mM (DMSO)50,00€10mg58,00€25mg110,00€50mg177,00€100mg286,00€200mg425,00€Optovin
CAS :Optovin is a TRPA1 activator, which is reversibly photoactivated.Formule :C15H13N3OS2Degré de pureté :99.47% - 99.67%Couleur et forme :SolidMasse moléculaire :315.41Ref: TM-T6617
2mg37,00€5mg54,00€1mL*10mM (DMSO)60,00€10mg88,00€25mg152,00€50mg236,00€100mg385,00€200mg560,00€GSK2193874
CAS :GSK2193874 was identified as a selective, orally active TRPV4 blocker.Formule :C37H38BrF3N4ODegré de pureté :99.99% - ≥95%Couleur et forme :SolidMasse moléculaire :691.62Ref: TM-T5640
1mg40,00€2mg54,00€5mg77,00€1mL*10mM (DMSO)105,00€10mg120,00€25mg234,00€50mg384,00€100mg570,00€JNJ-17203212
CAS :JNJ-17203212 is a potent and selective antagonist of TRPV1 (human TRPV1 and rat TRPV1, IC50 of 65 nM and 102 nM).Formule :C17H15F6N5ODegré de pureté :99.18%Couleur et forme :SolidMasse moléculaire :419.32M8-B Hydrochloride
CAS :M8-B Hydrochloride is a selective transient receptor potential melastatin-8 (TRPM8) channel antagonist.Formule :C22H25ClN2O3SDegré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :432.96Ref: TM-T8442
2mg34,00€5mg50,00€1mL*10mM (DMSO)60,00€10mg71,00€25mg138,00€50mg215,00€100mg318,00€200mg444,00€SB-366791
CAS :SB-366791 is a new and selective cinnamide TRPV1 antagonist.Formule :C16H14ClNO2Degré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :287.74Ononetin
CAS :Ononetin (2',4'-Dihydroxy-2-(4-methoxyphenyl)acetophenone) is a TRPM3 channel blocker(IC50: 0.3 μM).Formule :C15H14O4Degré de pureté :98.06%Couleur et forme :SolidMasse moléculaire :258.27Evifacotrep
CAS :Evifacotrep: TRPC5 antagonist for neurological disease research (WO2020061162, compound 100).Formule :C18H12ClF4N5O2Degré de pureté :98.6%Couleur et forme :SolidMasse moléculaire :441.77Ref: TM-T40042
1mg92,00€1mL*10mM (DMSO)152,00€5mg178,00€10mg286,00€25mg440,00€50mg655,00€100mg973,00€200mg1.468,00€HC067047 Hydrochloride(883031-03-6 free base)
CAS :HC-067047 hydrochloride, a TRPV4 antagonist, selectively inhibits human, rat, and mouse currents with IC50s: 486 nM, 133 nM, and 17 nM.Formule :C26H29ClF3N3O2Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :507.98Ref: TM-T4680L
1mg88,00€5mg172,00€1mL*10mM (DMSO)217,00€10mg259,00€25mg425,00€50mg598,00€100mg810,00€200mg1.074,00€HC-030031
CAS :HC-030031 (TOSLAB 829227) is a potent TRPA1 inhibitor, which antagonizes AITC- and formalin-evoked calcium influx with IC50s of 6.2 and 5.3 μM, respectively.Formule :C18H21N5O3Degré de pureté :99.69% - ≥95%Couleur et forme :SolidMasse moléculaire :355.39ML204
CAS :ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.Formule :C15H18N2Degré de pureté :98.1% - 99.72%Couleur et forme :SolidMasse moléculaire :226.32RN-1734
CAS :RN-1734 is selective TRPV4 channel antagonist(IC50 of 2.3 μM,5.9 μM,3.2 μM for hTRPV4, mTRPV4 and rTRPV4,respectively)Formule :C14H22Cl2N2O2SDegré de pureté :99.1% - 99.3%Couleur et forme :SolidMasse moléculaire :353.31AMG 333
CAS :AMG 333 is TRPM8 antagonist with an IC50 of 13 nM,a Clinical Candidate for the Treatment of Migraine.Formule :C20H12F5N3O4Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :453.32AMG 517
CAS :AMG 517 is an effective and specific TRPV1 antagonist, antagonizes proton (IC50: 0.76 nM), capsaicin (IC50: 0.62 nM) and heat activation (IC50: 1.3 nM) of TRPV1Formule :C20H13F3N4O2SDegré de pureté :99.77% - 99.85%Couleur et forme :SolidMasse moléculaire :430.4cim0216
CAS :CIM0216 is a synthetic TRPM3 activator whose potency and apparent affinity greatly exceeds that of the canonical TRPM3 agonist.Formule :C21H21N3O2Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :347.41Ref: TM-T9263
1mg44,00€2mg56,00€5mg87,00€1mL*10mM (DMSO)96,00€10mg138,00€25mg281,00€50mg442,00€100mg665,00€500mg1.378,00€Chembridge-5861528
CAS :Chembridge-5861528 (TCS 5861528) is a TRPA1 channel blocker that antagonizes AITC- and 4-HNE-evoked calcium influx with IC50 values of 14.3 and 18.7 μM.Formule :C19H23N5O3Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :369.42ASP7663
CAS :ASP7663 is a TRPA1 Receptor Agonist and exhibiting an abdominal analgesic effect in vivo.Formule :C14H14FNO3Degré de pureté :98.61%Couleur et forme :SolidMasse moléculaire :263.26RQ-00203078
CAS :RQ-00203078 is a highly selective, potent and orally available TRPM8 antagonist.Formule :C21H13ClF6N2O5SDegré de pureté :98% - 99.6%Couleur et forme :SolidMasse moléculaire :554.85A-967079
CAS :A 967079 is a potent, selective, and bioavailable inhibitor of the TRPA1 channel, with IC50 values of 67 and 289 nM for the human and rat isoforms, respectively
Formule :C12H14FNODegré de pureté :98.34% - 99.75%Couleur et forme :SolidMasse moléculaire :207.24SB-705498
CAS :SB705498 is a TRPV1 antagonist for hTRPV1. SB-705498 has been investigated for the treatment of Rhinitis, Chronic Cough, and Non-allergic Rhinitis.Formule :C17H16BrF3N4ODegré de pureté :99.57% - ≥95%Couleur et forme :SolidMasse moléculaire :429.23MDR-652
CAS :MDR-652 is a highly specific and efficacious agonist of nonpungent transient receptor potential vanilloid 1 (TRPV1) with Ki value of 11.4 nM and 23.8 nM forFormule :C22H23ClFN3O2SDegré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :447.95Ref: TM-T22360
1mg60,00€2mg87,00€5mg130,00€1mL*10mM (DMSO)142,00€10mg178,00€25mg331,00€50mg512,00€100mg707,00€200mg973,00€RN-1747
CAS :RN-1747: TRPV4 agonist (EC50: human 0.77 μM, mouse 4.0 μM, rat 4.1 μM), TRPM8 antagonist (IC50: 4 μM).Formule :C17H18ClN3O4SDegré de pureté :99.29%Couleur et forme :SolidMasse moléculaire :395.86JNJ-28583113
CAS :JNJ-28583113 is a TRPM2 antagonist, inducing phosphorylation of GSK3α and β subunits, protecting cells from oxidative stress-induced cell death.Formule :C19H21F3N2O2Degré de pureté :98.57%Couleur et forme :SolidMasse moléculaire :366.38Ref: TM-T74779
1mg94,00€5mg193,00€1mL*10mM (DMSO)213,00€10mg241,00€25mg387,00€50mg591,00€100mg754,00€200mg1.046,00€SAR7334
CAS :SAR7334 (TRCP6-IN-1) is a potent and specific inhibitor of TRPC6(IC50 of 7.9 nM).Formule :C21H22ClN3ODegré de pureté :99.62% - 99.71%Couleur et forme :SolidMasse moléculaire :367.87Ref: TM-T12849
1mg67,00€2mg88,00€5mg152,00€1mL*10mM (DMSO)166,00€10mg236,00€25mg295,00€50mg349,00€100mg439,00€200mg628,00€AM12
CAS :AM12 inhibits Lanthanide-evoked TRPC5 activity (IC50: 0.28 μM).Formule :C15H9BrO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :349.13Asivatrep
CAS :Asivatrep (PAC14028) is a selective and potent antagonist of transient receptor potential vanilloid subtype 1 (TRPV1) for the study of atopic dermatitis.Formule :C21H22F5N3O3SDegré de pureté :95.13%Couleur et forme :SolidMasse moléculaire :491.48GSK1702934A
CAS :GSK1702934A is a TRPC3 agonist with pro-arrhythmic and positive inotropic effects and is used in the study of diabetes mellitus.Formule :C22H25N3O2SDegré de pureté :98.15%Couleur et forme :SolidMasse moléculaire :395.52N-Oleoyl Valine
CAS :N-Oleoyl valine, an N-acyl amine, antagonizes TRPV3 for thermoregulation; rises post-cold exposure; elevates in mouse lung injury.Formule :C23H43NO3Masse moléculaire :381.59TRPC6-PAM-C20
CAS :TRPC6-PAM-C20, a selective enhancer for TRPC6, boosts calcium in HEK cells and OAG-related platelet clumping, EC50: 2.37μM.Formule :C22H21NO4Degré de pureté :98.16%Couleur et forme :SolidMasse moléculaire :363.41D-3263 hydrochloride
CAS :D-3263 hydrochloride (D3263 HCl salt) is enteric-coated, orally bioavailable transient receptor potential melatonin member 8 (TRPM8) agonist.
Formule :C21H32ClN3O3Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :409.95TRPV4 agonist-1
CAS :TRPV4 agonist-1 is an agonist of TRPV4 (EC50: 60 nM in the hTRPV4 Ca2+ assay).Formule :C25H23ClF2N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :484.93TRPM4-IN-2
CAS :NBA, or TRPM4-IN-2, is a potent TRPM4 inhibitor with IC50 of 0.16 μM, used in prostate and colorectal cancer research.Formule :C19H14ClNO4Degré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :355.77JYL 1421
CAS :JYL 1421 (SC 0030) is an antagonist of TRPV1 receptor (IC50 = 8 nM).Formule :C20H26FN3O2S2Degré de pureté :98.83%Couleur et forme :SolidMasse moléculaire :423.57Ref: TM-T15634
1mg66,00€1mL*10mM (DMSO)170,00€5mg177,00€10mg289,00€25mg580,00€50mg888,00€100mg1.414,00€200mg1.882,00€RN9893
CAS :RN9893 is a selective and potent TRPV4 receptor antagonist with IC50 values of 320, 420 and 660 nM for TRPV4 receptors in mouse, human and rat, respectively.Formule :C21H23F3N4O5SDegré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :500.49TRPV3 antagonist 74a
CAS :TRPV3 antagonist 74a (TRPV3 74a) is a specific TRPV3 antagonist for the study of neurological disorders.Formule :C17H17F3N2O2Degré de pureté :≥98.0%Couleur et forme :SolidMasse moléculaire :338.32Olvanil
CAS :Olvanil (N-Vannilyloleoylamide) is a vanilloid receptor agonist with EC50 of 0.7nM.Formule :C26H43NO3Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :417.62Ref: TM-T23106
2mg34,00€5mg49,00€1mL*10mM (DMSO)50,00€10mg75,00€25mg145,00€50mg236,00€100mg385,00€200mg560,00€SET 2
CAS :SET 2 is an antagonist of transient receptor potential vanilloid type 2(TRPV2) with an IC50 of 0.46 μM. SET 2 shows selectivity over TRPV1, TRPV3 and TRPV4.Formule :C17H21F3N4O2SDegré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :402.43Ref: TM-T37097
500mgÀ demander5mg55,00€1mL*10mM (DMSO)67,00€10mg92,00€25mg168,00€50mg284,00€100mg414,00€Elismetrep
CAS :Elismetrep (MT-8554) is an orally available TRPM8 inhibitor with potential analgesic activity for the study of vasomotor symptoms in postmenopausal women.Formule :C27H21F3N2O5SDegré de pureté :99.37% - 99.93%Couleur et forme :SolidMasse moléculaire :542.53HC-070
CAS :HC-070 is a TRPC5 and TRPC4 antagonist (IC50 = 9.3 nM and 46 nM).Formule :C22H20Cl2N4O4Degré de pureté :98.48%Couleur et forme :SolidMasse moléculaire :475.32Ref: TM-T15465
1mg84,00€5mg160,00€1mL*10mM (DMSO)165,00€10mg236,00€25mg406,00€50mg572,00€100mg772,00€200mg1.035,00€Mavatrep
CAS :Mavatrep (JNJ-39439335) is a selective antagonist of TRPV1 with Ki of 6.5 nM and can be used for studies about inflammatory pain.Formule :C25H21F3N2ODegré de pureté :98.51% - 99.31%Couleur et forme :SolidMasse moléculaire :422.44Ref: TM-T16014
1mg63,00€2mg90,00€5mg137,00€1mL*10mM (DMSO)150,00€10mg215,00€25mg385,00€50mg618,00€100mg888,00€200mg1.243,00€MSP3
CAS :MSP3 is an agonist of TRPV1 (EC50 = 0.87 μM) and shows antinociceptive and neuroprotective effects.Formule :C16H19NO3SDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :305.39Ref: TM-T28118
2mg33,00€5mg50,00€1mL*10mM (DMSO)71,00€10mg80,00€25mg161,00€50mg243,00€100mg358,00€200mg505,00€TC-I 2014
CAS :TC-I 2014 shows antiallodynic properties in pain models.Formule :C23H19F6N3ODegré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :467.41Ref: TM-T17006
1mg57,00€5mg120,00€1mL*10mM (DMSO)126,00€10mg192,00€25mg385,00€50mg620,00€100mg1.018,00€200mg1.378,00€FEMA-4809
CAS :FEMA-4809 activates TRPM8, the ion channel for cold sensation, and is used as a cooling agent.Formule :C17H17N3O2SDegré de pureté :99.9%Couleur et forme :SolidMasse moléculaire :327.4Ref: TM-T27308
1mg34,00€5mg73,00€1mL*10mM (DMSO)84,00€10mg110,00€25mg180,00€50mg255,00€100mg363,00€200mg497,00€Pyr3
CAS :Pyr3 selectively blocks TRPC3 channels, reducing Ca2+ influx; it's effective at 700 nM.Formule :C16H11Cl3F3N3O3Degré de pureté :98.04%Couleur et forme :SolidMasse moléculaire :456.63Ref: TM-T16687
1mg35,00€2mg52,00€5mg77,00€1mL*10mM (DMSO)86,00€10mg97,00€25mg215,00€50mg363,00€100mg512,00€200mg738,00€500mg1.121,00€ABT 102
CAS :ABT 102 (CHEMBL398338) is a selective antagonist of transient receptor potential vanilloid 1 (TRPV1) receptor.Formule :C21H24N4ODegré de pureté :98.38% - 99.86%Couleur et forme :SolidMasse moléculaire :348.44Ref: TM-T29522
1mg109,00€5mg235,00€1mL*10mM (DMSO)245,00€10mg349,00€25mg532,00€50mg745,00€100mg999,00€200mg1.333,00€JT010
CAS :JT010 is an effective agonist of TRPA1 (EC50 = 0.65 nM).Formule :C16H19ClN2O3SDegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :354.85PF-05105679
CAS :PF-05105679 is a selective TRPM8 antagonist (IC50 = 103 nM). PF-05105679 can be used in research on cold-related pain.Formule :C26H21FN2O3Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :428.45Ref: TM-T16483
1mg44,00€2mg57,00€1mL*10mM (DMSO)90,00€5mg93,00€10mg138,00€25mg264,00€50mg404,00€100mg610,00€200mg848,00€GSK3395879
CAS :GSK3395879 is a selective and orally bioavailable antagonist of transient receptor potential vanilloid-4 (TRPV4) (IC50: 1 nM for hTRPV4).Formule :C20H15F4N3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :485.41Mesendogen
CAS :Mesendogen is an inhibitor of transient receptor potential cation channel, subfamily M, member 6 (TRPM6) and 7 (TRPM7) and acts by inhibiting TRPM6/TRPM7Formule :C18H16ClF3N2OSDegré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :400.85A-1165442
CAS :A-1165442 is a competitive TRPV1 antagonist. For human TRPV, the IC50 values is 9 nM.Formule :C22H20ClF2N3O2Couleur et forme :SolidMasse moléculaire :431.86MK-2295
CAS :MK-2295 is a potent TRPV1 antagonist. MK-2295 can be used in studies about the treatment of chronic pain.Formule :C27H31FN6O2Degré de pureté :98.83% - 99.44%Couleur et forme :SolidMasse moléculaire :490.57AMG-0347
CAS :AMG-0347 inhibits TRPA1 ion channels in sensory neurons, blocking pain perception.Formule :C24H26F3N3O2Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :445.48Ref: TM-T29968
1mg215,00€5mg523,00€1mL*10mM (DMSO)537,00€10mg695,00€25mg1.054,00€50mg1.414,00€100mg1.900,00€200mg2.565,00€AMG2850
CAS :AMG2850 is a potent, orally bioavailable, and selective antagonist of transient receptor potential melastatin 8 (TRPM8).Formule :C19H17F6N3ODegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :417.35Ref: TM-T10300
1mg71,00€5mg161,00€1mL*10mM (DMSO)172,00€10mg235,00€25mg423,00€50mg627,00€100mg803,00€ELP-004
CAS :ELP-004 is a TRPC channel inhibitor that blocks Ca2+ entry mediated by TRPC channels. It serves as an osteoclast inhibitor by preventing osteoclast differentiation. ELP-004 also hinders basal Ca2+ levels and the associated translocation of NFATc1 in inflammatory osteoclastogenesis. Additionally, it reduces bone erosion in mouse models of rheumatoid arthritis.Formule :C10H11Cl2NOCouleur et forme :SolidMasse moléculaire :232.106TRPA1 Antagonist 1
CAS :TRPA1 Antagonist 1 is an antagonist of TRPA1(IC50: 8 nM) and is a methylene phosphate prodrug which converts to its active parent drug.Formule :C24H20F6N5Na2O7PSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :713.45Apcin A HCL
CAS :Apcin A HCL is an Apcin derivative. Apcin A HCL is an anaphase-promoting complex (APC) inhibitor. Apcin-A HCL interacts strongly with Cdc20, and inhibits the ubiquitination of Cdc20 substrates. Apcin-A HCL can be used to synthesize the PROTAC CP5V [1].
Formule :C10H15Cl4N5O2Degré de pureté :99.30%Couleur et forme :SolidMasse moléculaire :379.07Ref: TM-T001
Produit arrêtéMotugivatrep
CAS :Motugivatrep is a potent and selective TRPV1 antagonist that can be used to study TRPV1-related respiratory diseases.
Formule :C22H20F3NO3Degré de pureté :99.22%Couleur et forme :SolidMasse moléculaire :403.39
