Pompe à protons
Les pompes à protons sont des protéines membranaires qui transportent activement des protons (H+) à travers la membrane cellulaire ou les membranes des organites, créant un gradient de protons essentiel à divers processus cellulaires. La pompe à protons la plus connue est l'H+/K+ ATPase, présente dans la muqueuse de l'estomac, responsable de la sécrétion acide. Les pompes à protons sont également cruciales dans la respiration cellulaire et la régulation du pH. La dysrégulation de l'activité des pompes à protons est associée à des conditions telles que le reflux acide, les ulcères et l'acidose métabolique. Chez CymitQuimica, nous proposons une sélection d'inhibiteurs et de modulateurs de la pompe à protons pour soutenir vos recherches en gastroentérologie, métabolisme et bioénergétique cellulaire.
39 produits trouvés pour "Pompe à protons"
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Omeprazole sulfide
CAS :<p>Omeprazole sulfide (Ufiprazole), a metabolite of Omeprazole, functions as a proton pump inhibitor.</p>Formule :C17H19N3O2SDegré de pureté :98.83%Couleur et forme :White To Slightly Collored Solid Solid CrystallineMasse moléculaire :329.42EN6
CAS :<p>EN6, a small molecule, activates autophagy by modifying ATP6V1A, inhibiting mTORC1 and enhancing lysosomal function to clear TDP-43 aggregates.</p>Formule :C19H14F2N4O2Degré de pureté :95.74% - 97.04%Couleur et forme :SolidMasse moléculaire :368.34Lansoprazole
CAS :<p>Lansoprazole (A-65006) is a 2, 2, 2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON</p>Formule :C16H14F3N3O2SDegré de pureté :99.18% - 99.84%Couleur et forme :White Crystalline PowderMasse moléculaire :369.36Zinc pyrithione
CAS :<p>Zinc pyrithione (OM-1563), an antibacterial and antifungal agent can disrupt membrane transport by blocking the proton pump.</p>Formule :C10H8N2O2S2ZnDegré de pureté :99.09% - 99.47%Couleur et forme :Off-White To Tan PowderMasse moléculaire :317.71Omeprazole
CAS :<p>Omeprazole (Losec) is a proton pump inhibitor (PPI), Omeprazole(Losec) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor.</p>Formule :C17H19N3O3SDegré de pureté :98.43% - 98.48%Couleur et forme :White SolidMasse moléculaire :345.42Corza6
<p>Corza6 is a potent and selective peptide inhibitor of the human voltage-gated proton channel (hHv1). It binds to the external voltage sensor domain (VSD) loop in hHv1 at a resting membrane potential (RMP) of natural hyperpolarization in mammalian cells with a Kd of approximately 1 nM. Corza6 facilitates sperm capacitation and permits sustained production of reactive oxygen species (ROS) in leukocytes (WBC).</p>Formule :C203H293N55O61S7Couleur et forme :SolidMasse moléculaire :4704.29Pantoprazole Sodium Hydrate
CAS :<p>Pantoprazole Sodium Hydrate (BY1023 (sodium hydrate)) is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagus</p>Formule :C16H14F2N3NaO4SH2ODegré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :432.37Tenatoprazole
CAS :<p>Tenatoprazole (TU-199), a prodrug of the proton pump inhibitor (PPI) class, can inhibit proton transport (IC50: 3.2 μM).</p>Formule :C16H18N4O3SDegré de pureté :99.57%Couleur et forme :White Crystalline PowderMasse moléculaire :346.4Esomeprazole
CAS :<p>Esomeprazole is the S-isomer of omeprazole, inhibits the lysosomal cysteine protease legumain to prevent cancer metastasis.</p>Formule :C17H19N3O3SDegré de pureté :97.3%Couleur et forme :SolidMasse moléculaire :345.42(R)-Lansoprazole
CAS :<p>(R)-Lansoprazole (T 168390) is the R-isomer of lansoprazole and a substituted benzimidazole prodrug with selective and irreversible proton pump inhibitor</p>Formule :C16H14F3N3O2SDegré de pureté :98.09% - 98.99%Couleur et forme :Brown SolidMasse moléculaire :369.36Esomeprazole Magnesium trihydrate
CAS :<p>Esomeprazole Magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a proton pump inhibitor indicated for the short-term treatment of gastroesophageal</p>Formule :C34H42MgN6O9S2Degré de pureté :98.52%Couleur et forme :Off-White PowderMasse moléculaire :767.17Thonzonium Bromide
CAS :<p>Thonzonium bromide: antimicrobial surfactant, similar to Farnesol, blocks proton transport, inhibits bone loss (EC50=69 μM).</p>Formule :C32H55BrN4ODegré de pureté :98.48% - 99.94%Couleur et forme :SolidMasse moléculaire :591.71Rabeprazole Sulfide
CAS :<p>Rabeprazole Sulfide (Rabeprazole Related Compound E) is an antiulcer drug in the class of proton pump inhibitors.</p>Formule :C18H21N3O2SDegré de pureté :99.34% - 99.78%Couleur et forme :Off-White Crystalline PowderMasse moléculaire :343.44Vonoprazan
CAS :<p>Vonoprazan (TAK-438 (free base)) is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer and</p>Formule :C17H16FN3O2SDegré de pureté :99.87% - 99.92%Couleur et forme :SolidMasse moléculaire :345.39Esomeprazole Sodium
CAS :<p>Esomeprazole Sodium ((S)-Omeprazole sodium) is the S-isomer of omeprazole with selective and irreversible proton pump inhibitor activity.</p>Formule :C17H18N3O3S·NaDegré de pureté :98.17% - >99.99%Couleur et forme :SolidMasse moléculaire :367.4Tegoprazan
CAS :<p>Tegoprazan is an orally active, highly selective gastric H+/K+-ATPase inhibitor.Cost-effective and quality-assured.</p>Formule :C20H19F2N3O3Degré de pureté :98.22%Couleur et forme :SolidMasse moléculaire :387.38Chebulinic acid
CAS :<p>Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit SMAD-3 phosphorylation and H+ K+-ATPase activity.</p>Formule :C41H32O27Degré de pureté :98.91% - 99.71%Couleur et forme :SolidMasse moléculaire :956.68Ilaprazole sodium
CAS :<p>Ilaprazole sodium (IY-81149 sodium) , a substituted benzimidazole prodrug, is a selective and irreversible proton pump inhibitor.</p>Formule :C19H17N4NaO2SDegré de pureté :99.06%Couleur et forme :SolidMasse moléculaire :388.42Esomeprazole Magnesium
CAS :<p>Esomeprazole Magnesium (NEXIUM) is the S-isomer of omeprazole, can reduce gastric acid secretion with selective and irreversible proton pump inhibitor activity.</p>Formule :C34H36MgN6O6S2Degré de pureté :98.76% - 99.73%Couleur et forme :SolidMasse moléculaire :713.12Abscisic Acid
CAS :<p>Abscisic Acid (Dormin) is a plant hormone, which is involved in many plant developmental processes, modulates ion homeostasis and metabolism.</p>Formule :C15H20O4Degré de pureté :99.52% - 99.73%Couleur et forme :White PowderMasse moléculaire :264.32Pantoprazole sodium
CAS :<p>Pantoprazole sodium is a proton pump inhibitor that irreversibly blocks gastric acid secretion by bonding with H+/K+-ATPase.</p>Formule :C16H14F2N3NaO4SDegré de pureté :96.92% - 99.81%Couleur et forme :White To Off-White SolidMasse moléculaire :405.35Ilaprazole
CAS :<p>Ilaprazole (IY-81149) is a proton pump inhibitor used in the treatment of dyspepsia gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer.</p>Formule :C19H18N4O2SDegré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :366.44Rabeprazole sodium
CAS :<p>Rabeprazole sodium treats stomach ulcers and Zollinger-Ellison syndrome, blocking ATPase in gastric cells.</p>Formule :C18H20N3NaO3SDegré de pureté :98% - 99.912%Couleur et forme :White Or Off White Crystalline PowderMasse moléculaire :381.42Bafilomycin A1
CAS :<p>Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase (IC50=0.44 nM) that is specific and reversible.</p>Formule :C35H58O9Degré de pureté :95.87% - 99.36%Couleur et forme :SolidMasse moléculaire :622.83Vonoprazan Fumarate
CAS :<p>Vonoprazan Fumarate (TAK438) , a novel potassium-competitive acid blocker, inhibits gastric acid secretion.</p>Formule :C21H20FN3O6SDegré de pureté :98.94%Couleur et forme :SolidMasse moléculaire :461.46Pantoprazole
CAS :<p>Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux</p>Formule :C16H15F2N3O4SDegré de pureté :99.28% - 99.63%Couleur et forme :Almost White SolidMasse moléculaire :383.37KM 91104
CAS :<p>KM 91104 is a cell permeable inhibitor of V-ATPase. KM91104 specifically targets the interaction between V-ATPase subunit A3 and subunit B2.</p>Formule :C14H12N2O4Degré de pureté :99.04%Couleur et forme :SolidMasse moléculaire :272.26Diphyllin
CAS :<p>Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling.</p>Formule :C21H16O7Degré de pureté :99.76% - 99.98%Couleur et forme :SolidMasse moléculaire :380.35ATP4A Protein, Human, Recombinant (His & Myc)
<p>ATP4A Protein, Human, Recombinant (His & Myc) is expressed in E.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :54.6 kDa (predicted)Omeprazole Sodium
CAS :<p>Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion.</p>Formule :C17H18N3NaO3SDegré de pureté :99.84%Couleur et forme :Clear In WaterMasse moléculaire :367.4WY-47766
CAS :<p>WY-47766, a proton pump inhibitor, is used potentially for the treatment of postmenopausal osteoporosis.</p>Formule :C14H13N3O2SDegré de pureté :97.63% - 99.83%Couleur et forme :SolidMasse moléculaire :287.34Saviprazole
CAS :<p>Saviprazole (Hoe-731), a proton pump inhibitor, is used potentially for treatment of gastric ulcer.</p>Formule :C15H10F7N3O2S2Degré de pureté :97.07% - 97.17%Couleur et forme :SolidMasse moléculaire :461.38Abeprazan hydrochloride
CAS :<p>Abeprazan hydrochloride (Fexuprazan hydrochloride) is an effective reversible potassium-competitive acid blocker with oral activity, inhibiting H+, K+ -atPase</p>Formule :C19H18ClF3N2O3SDegré de pureté :98.57%Couleur et forme :SolidMasse moléculaire :446.87Ilaprazole sodium hydrate
CAS :<p>Ilaprazole sodium hydrate (IY-81149 sodium hydrate) is a proton pump inhibitor that blocks the transport of HSV particles.</p>Formule :C19H21N4NaO4SDegré de pureté :99.2%Couleur et forme :SolidMasse moléculaire :424.45Linaprazan
CAS :<p>Linaprazan (AZD0865) inhibits gastric H+,K+-ATPase by K+-competitive binding with an IC50 of 1.0 μM.</p>Formule :C21H26N4O2Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :366.46Pumaprazole
CAS :<p>Pumaprazole (BY-841) is an antagonist of a reversible proton pump.</p>Formule :C19H22N4O2Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :338.4Soraprazan
CAS :<p>BS3 Crosslinker (Bis(sulfosuccinimidyl)suberate) is an ADC linker that can be used to synthesize antibody-coupled active molecules.</p>Formule :C21H25N3O3Degré de pureté :97.69% - 99.84%Couleur et forme :SolidMasse moléculaire :367.44V-ATPase-IN-1
CAS :<p>V-ATPase-IN-1 (Compound 3b-03) is an inhibitor of Vacuolar-type H+-ATPases (V-ATPase), exhibiting an inhibition constant (IC50) of 194.80 μM and effectively targeting the V-ATPase subunit A with a dissociation constant (Kd) of 0.803 μM. This compound demonstrates insecticidal activity against M. separata (LC50 = 2.64 mM), aiding in the development of chemical insecticides.</p>Formule :C21H20ClNO2Couleur et forme :SolidMasse moléculaire :353.84Zastaprazan
CAS :<p>Zastaprazan (JP-1366, compound 6) is a potassium-competitive acid blocker and proton pump inhibitor that suppresses gastric acid secretion, indicated for GERD.</p>Formule :C22H26N4ODegré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :362.48
