Canal calcique
Les canaux calciques sont des protéines membranaires qui régulent le flux d'ions calcium dans et hors des cellules, ce qui est essentiel pour diverses fonctions cellulaires, y compris la contraction musculaire, la libération de neurotransmetteurs et l'expression génique. La dysrégulation de l'activité des canaux calciques est associée à des conditions telles que l'hypertension, les arythmies cardiaques et les troubles neurologiques. Chez CymitQuimica, nous proposons une large sélection de modulateurs des canaux calciques pour soutenir vos recherches en santé cardiovasculaire, neurobiologie et transduction du signal.
493 produits trouvés pour "Canal calcique"
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Argireline
CAS :<p>Argireline (Acetyl hexapeptide-3) is a peptide that inhibits neurotransmitter release, reducing wrinkles.</p>Formule :C34H60N14O12SDegré de pureté :96.79% - 99.65%Couleur et forme :White PowderMasse moléculaire :888.99Propiverine hydrochloride
CAS :<p>Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB).</p>Formule :C23H30ClNO3Degré de pureté :99.93%Couleur et forme :White Crystalling PowerMasse moléculaire :403.94Praeruptorin E
CAS :<p>Praeruptorin C/E relaxes arteries, reduces heart contractility, acting like calcium blockers. D/E protect mice from acid lung injury by halting PMNs and IL-6.</p>Formule :C24H28O7Degré de pureté :98.04% - 99.95%Couleur et forme :SolidMasse moléculaire :428.47SR33805
CAS :<p>SR33805 is a potent antagonist of Ca2+ channel(EC50s of 4.1 nM and 33 nM in depolarized and polarized conditions, respectively)</p>Formule :C32H40N2O5SDegré de pureté :99.15%Couleur et forme :SolidMasse moléculaire :564.74Lomerizine dihydrochloride
CAS :<p>Lomerizine dihydrochloride (KB-2796) is an antagonist of L- and T-type voltage-gated calcium channels used to treat migraine.</p>Formule :C27H30F2N2O3·2HClDegré de pureté :99.26% - 99.80%Couleur et forme :Colourless Crystalline SolidMasse moléculaire :541.46L-Phenylalanine
CAS :<p>L-Phenylalanine (3-Phenyl-L-alanine) is an essential amino acid and the precursor of the amino acid tyrosine, acts as an antagonist at α2δ calcium channels.</p>Formule :C9H11NO2Degré de pureté :99.37% - 99.87%Couleur et forme :Solid CrystallineMasse moléculaire :165.19Bepridil hydrochloride
CAS :<p>Bepridil hydrochloride (CERM 1978) is a calcium channel blocker and also inhibits Na+/Ca2+ exchange (NCX), sodium channels and cardiac sarcolemmal KATP channels</p>Formule :C24H35ClN2ODegré de pureté :99.45% - 99.68%Couleur et forme :SolidMasse moléculaire :403Azumolene
CAS :<p>Azumolene (EU4093 free base)</p>Formule :C13H9BrN4O3Degré de pureté :98.1% - 98.35%Couleur et forme :SolidMasse moléculaire :349.14NFAT Inhibitor-2
CAS :<p>NFAT Inhibitor-2 is a compound used as a molecular building block.</p>Formule :C22H20F2N2O4SDegré de pureté :97.37%Couleur et forme :SolidMasse moléculaire :446.47Dantrolene sodium hemiheptahydrate
CAS :<p>Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1 and decreasing intracellular calcium</p>Formule :C14H9N4NaO5·5H2ODegré de pureté :99.72%Couleur et forme :Orange PowderMasse moléculaire :399.29Ethacrynic acid
CAS :<p>Ethacrynic acid (Edecrin) 是谷胱甘肽 S-转移酶抑制剂，也是NF-κB 信号传导途径的有效抑制剂，并且还调节白三烯的形成。它还可抑制 L 型电压依赖性和储存操作的钙通道，从而导致气道平滑肌细胞松弛。它是利尿剂，具有抗炎特性，可减轻类维生素 A 诱导的小鼠耳部水肿。</p>Formule :C13H12Cl2O4Degré de pureté :98.61% - 99.85%Couleur et forme :Crystals Physical Description White Solid (Ntp 1992)Masse moléculaire :303.14Gabapentin hydrochloride
CAS :<p>Gabapentin hydrochloride (Neurontin HCl) is a GABA analogue, used to treat seizures and neuropathic pain.</p>Formule :C9H17NO2·HClDegré de pureté :99.71%Couleur et forme :Off-White SolidMasse moléculaire :207.7NS-638
CAS :<p>NS-638 is a Ca2+-channel blocker. It can block K+-stimulated intracellular Ca2+-elevation (IC50: 3.4 μM).</p>Formule :C15H11ClF3N3Degré de pureté :98.44%Couleur et forme :SolidMasse moléculaire :325.72Cycleanine
CAS :<p>Cycleanine has potent antibacterial, antifungal, antiplasmodial, and cytotoxic activities.</p>Formule :C38H42N2O6Degré de pureté :98.04% - 99.57%Couleur et forme :SolidMasse moléculaire :622.75Pranidipine
CAS :<p>Pranidipine (OPC-13340) is a novel, long-acting 1,4-dihydropyridine calcium channel blocker.</p>Formule :C25H24N2O6Degré de pureté :99.95%Couleur et forme :Yellow SolidMasse moléculaire :448.47Glaucine
CAS :<p>Glaucine: antitussive, antioxidative, antiviral, may fight arthritis, boosts IL-10, hinders breast cancer cell spread by inhibiting MMP-9 and NF-κB.</p>Formule :C21H25NO4Degré de pureté :99.42% - 99.56%Couleur et forme :SolidMasse moléculaire :355.43FPL64176
CAS :<p>FPL64176 is a L-type calcium channels activator.</p>Formule :C22H21NO3Degré de pureté :98.68%Couleur et forme :SolidMasse moléculaire :347.41Aranidipine
CAS :<p>Aranidipine (MPC1304) (MPC1304) is a calcium channel antagonist with potent and long-lasting antihypertensive effects.</p>Formule :C19H20N2O7Degré de pureté :99.15%Couleur et forme :SolidMasse moléculaire :388.37TTA-A2
CAS :<p>TTA-A2: T-type calcium channel blocker; anticonvulsant targeting Cav3.1, Cav3.2; IC50 of 89/92 nM; potential for treating neurological conditions.</p>Formule :C20H21F3N2O2Degré de pureté :99.5% - 99.9%Couleur et forme :SolidMasse moléculaire :378.39Gomisin J
CAS :<p>Gomisin J is a natural product and have vasodilatory activity.</p>Formule :C22H28O6Degré de pureté :99.59% - 99.60%Couleur et forme :SolidMasse moléculaire :388.45Fantofarone
CAS :<p>Fantofarone (SR 33557) is a highly potent antagonist of Calcium Channel.</p>Formule :C31H38N2O5SDegré de pureté :96.13% - 99.19%Couleur et forme :SolidMasse moléculaire :550.71Fasudil hydrochloride
CAS :<p>Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.</p>Formule :C14H18ClN3O2SDegré de pureté :99.54% - ≥95%Couleur et forme :White SolidMasse moléculaire :327.83Ziconotide Acetate (107452-89-1 free base)
CAS :<p>Ziconotide Acetate (Prialt, 107452-89-1) is an analgesic for neuropathic pain, acting on N-type calcium channels to block pain signals.</p>Formule :C102H172N36O32S7Degré de pureté :99.52% - 99.87%Couleur et forme :SolidMasse moléculaire :2639.2Norfluoxetine Hydrochloride
CAS :<p>Norfluoxetine Hydrochloride (Norfluoxetine HCl) is an active metabolite of fluoxetine. Fluoxetine is an antidepressant drug.</p>Formule :C16H17ClF3NODegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :331.76Lanthanum(III) chloride heptahydrate
CAS :<p>Lanthanum(III) chloride blocks divalent cation channels, useful for biochemical research.</p>Formule :Cl3H14LaO7Degré de pureté :98%Couleur et forme :White Solid PowderMasse moléculaire :371.37Almorexant
CAS :<p>Almorexant (ACT 078573), a strong dual orexin receptor antagonist, has Ki of 1.3 nM for OX1 and 0.17 nM for OX2.</p>Formule :C29H31F3N2O3Degré de pureté :97.75% - 98.02%Couleur et forme :SolidMasse moléculaire :512.56Barnidipine hydrochloride
CAS :<p>Barnidipine HCl is a potent dihydropyridine Ca²⁺ blocker with 0.35 nM IC50 in pig coronary artery.</p>Formule :C27H30ClN3O6Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :528(±)-Praeruptorin A
CAS :<p>(±)-Praeruptorin A could exhibit its anti-osteoclastogenic activity by inhibiting p38/Akt-c-Fos-NFATc1 signaling and PLCγ-independent Ca(2+) oscillation.</p>Formule :C21H22O7Degré de pureté :98.9% - 99.73%Couleur et forme :SolidMasse moléculaire :386.4Manidipine
CAS :<p>Manidipine (Iperten), a calcium channel blocker, which is dihydropyridine type. It is utilized</p>Formule :C35H38N4O6Degré de pureté :99.30%Couleur et forme :SolidMasse moléculaire :610.7ISX-9
CAS :<p>ISX-9 (Isoxazole 9) is necessary to activate neuron-specific genes as neurogenesis inducer.</p>Formule :C11H10N2O2SDegré de pureté :97.81% - ≥95%Couleur et forme :SolidMasse moléculaire :234.27YM-58483
CAS :<p>YM-58483 (BTP2) is a specific and effective inhibitor of CRAC channels and subsequent Ca2+ signals.</p>Formule :C15H9F6N5OSDegré de pureté :99.33% - 99.64%Couleur et forme :SolidMasse moléculaire :421.32Z944
CAS :<p>Z944 is a T-type calcium channel blocker.</p>Formule :C19H27ClFN3O2Degré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :383.89Barnidipine
CAS :<p>Barnidipine (YM-09730-5(Free base)) is a calcium channel blocker.</p>Formule :C27H29N3O6Degré de pureté :99.98%Couleur et forme :SolidMasse moléculaire :491.54Ginsenoside Rf
CAS :<p>Ginsenoside Rf (Panaxoside Rf) is a trace component of ginseng root. Ginsenoside Rf inhibits N-type Ca2+ channel.</p>Formule :C42H72O14Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :801.01Urolithin C
CAS :<p>Urolithin C is a gut metabolite of ellagic acid. Urolithin C induces apoptosis in PC12 cells through a mitochondria-mediated pathway.</p>Formule :C13H8O5Degré de pureté :98.01% - 99.53%Couleur et forme :SolidMasse moléculaire :244.2Ginsenoside Ro
CAS :<p>Ginsenoside Ro (Chikusetsusaponin V) can reduce TXA2 production, weakly reduce COX-1 and TXAS activities, and has antiplatelet effects as a Ca2+ antagonist with</p>Formule :C48H76O19Degré de pureté :98% - 99.66%Couleur et forme :SolidMasse moléculaire :957.11Isradipine
CAS :<p>Isradipine (PN 200-110), a dihydropyridine, is an antihypertensive calcium channel blocker that dilates arteries and reduces resistance.</p>Formule :C19H21N3O5Degré de pureté :99.84% - 99.95%Couleur et forme :Yellow SolidMasse moléculaire :371.39Ruthenium Red
CAS :<p>Ruthenium Red (Ammoniated ruthenium oxychloride) is a polycationic dye widely used for electron microscopy (EM) of cells, tissues and vegetative bacteria.</p>Formule :Cl6H42N14O2Ru3Degré de pureté :95%Couleur et forme :Purple PowderMasse moléculaire :786.34Benidipine hydrochloride
CAS :<p>Benidipine hydrochloride (Coniel) , a hydrochloride salt form of benidipine, is used as a blocker of dihydropyridine calcium channel.</p>Formule :C28H32ClN3O6Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :542.032-Aminoethyl diphenylborinate
CAS :<p>2-Aminoethyl diphenylborinate (2-APB) is a chemical that acts to inhibit both IP3 receptors and TRP channels.</p>Formule :C14H16BNODegré de pureté :98.74% - 99.92%Couleur et forme :WhiteMasse moléculaire :225.09Cyclopiazonic acid
CAS :<p>Cyclopiazonic acid (CPA) is a neurotoxic secondary metabolite (SM) made by A.</p>Formule :C20H20N2O3Degré de pureté :99.27% - 99.80%Couleur et forme :SolidMasse moléculaire :336.38Ned 19
CAS :<p>Ned 19 inhibits tumor growth, vascularization, lung metastases in mice, and is a selective NAADP antagonist.</p>Formule :C30H31FN4O3Degré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :514.59Etripamil
CAS :<p>Etripamil is a fast-acting intranasal L-type calcium-channel blocker for Paroxysmal Supraventricular Tachycardia.</p>Formule :C27H36N2O4Degré de pureté :99.47% - 99.83%Couleur et forme :SolidMasse moléculaire :452.59Levamlodipine besylate
CAS :<p>Levamlodipine besylate, or S-amlodipine (CAS 103129-82-4), is the active enantiomer of amlodipine, used to treat hypertension and angina.</p>Formule :C26H31ClN2O8SDegré de pureté :99.78% - 99.79%Couleur et forme :SolidMasse moléculaire :567.05Dronedarone
CAS :<p>Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.</p>Formule :C31H44N2O5SDegré de pureté :98.85% - 99.58%Couleur et forme :SolidMasse moléculaire :556.76Nicardipine
CAS :<p>Nicardipine (Cardene), a calcium channel blockers belonging to the dihydropyridine class, is a drug used to treat angina and high blood pressure.</p>Formule :C26H29N3O6Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :479.52CDN1163
CAS :<p>CDN1163 is a small molecule activator of sarco/endoplasmic reticulum Ca2+-ATPase (SERCA).</p>Formule :C20H20N2O2Degré de pureté :99.83% - ≥95%Couleur et forme :SolidMasse moléculaire :320.39Efonidipine
CAS :<p>Efonidipine (NZ-105)(NZ-105) is a dihydropyridine calcium channel blocker, blocking both T-type and L-type calcium channels.</p>Formule :C34H38N3O7PDegré de pureté :98.35% - 99.47%Couleur et forme :SolidMasse moléculaire :631.66OPHIOPOGONIN D
CAS :<p>Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.</p>Formule :C44H70O16Degré de pureté :99.46% - ≥95%Couleur et forme :SolidMasse moléculaire :855.02Yangambin
CAS :<p>Yangambin: selective PAF antagonist, hypotensive, inhibits Ca2+ influx, induces peripheral vasodilation, affects CNS.</p>Formule :C24H30O8Degré de pureté :98.02%Couleur et forme :SolidMasse moléculaire :446.49
