Canal calcique
Les canaux calciques sont des protéines membranaires qui régulent le flux d'ions calcium dans et hors des cellules, ce qui est essentiel pour diverses fonctions cellulaires, y compris la contraction musculaire, la libération de neurotransmetteurs et l'expression génique. La dysrégulation de l'activité des canaux calciques est associée à des conditions telles que l'hypertension, les arythmies cardiaques et les troubles neurologiques. Chez CymitQuimica, nous proposons une large sélection de modulateurs des canaux calciques pour soutenir vos recherches en santé cardiovasculaire, neurobiologie et transduction du signal.
573 produits trouvés pour "Canal calcique"
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Dronedarone
CAS :Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.Formule :C31H44N2O5SDegré de pureté :98.85% - 99.99%Couleur et forme :SolidMasse moléculaire :556.76RO2959 Hydrochloride
CAS :RO2959 Hydrochloride (RO2959 HCl) is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.Formule :C21H20ClF2N5OSDegré de pureté :99.24%Couleur et forme :SolidMasse moléculaire :463.93Ginsenoside Rd
CAS :Ginsenoside Rd (Gypenoside VIII) may have properties that inhibit or prevent the growth of tumors.Formule :C48H82O18Degré de pureté :99.13% - 99.92%Couleur et forme :SolidMasse moléculaire :947.15Ref: TM-T2878
1mg37,00€5mg71,00€10mg99,00€25mg170,00€50mg260,00€100mg394,00€200mg570,00€1mL*10mM (DMSO)124,00€Azumolene sodium anhydrous
CAS :Azumolene sodium, a muscle relaxant, blocks calcium release from muscles and halts SOCE linked to RyR1 except when induced by thapsigargin.Formule :C13H8BrN4NaO3Couleur et forme :SolidMasse moléculaire :371.13Pyr6
CAS :Pyr6 (N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-4-pyridinecarboxamide) is a selective TRPC3 inhibitor with IC50 of 0.49 uM(Ca2+ influxFormule :C17H9F7N4ODegré de pureté :98.89%Couleur et forme :SolidMasse moléculaire :418.27Pranidipine
CAS :Pranidipine (OPC-13340) is a novel, long-acting 1,4-dihydropyridine calcium channel blocker.Formule :C25H24N2O6Degré de pureté :99.95%Couleur et forme :Yellow SolidMasse moléculaire :448.47Aranidipine
CAS :Aranidipine (MPC1304) (MPC1304) is a calcium channel antagonist with potent and long-lasting antihypertensive effects.Formule :C19H20N2O7Degré de pureté :99.15%Couleur et forme :SolidMasse moléculaire :388.37JNJ-26990990
CAS :"JNJ-26990990: broad-spectrum anticonvulsant, less side effects than topiramate, potential for pain and depression treatment; Phase II in 2007."Formule :C9H10N2O2S2Degré de pureté :97.37%Couleur et forme :SolidMasse moléculaire :242.32Ref: TM-T27673
1mg84,00€5mg168,00€10mg241,00€25mg399,00€50mg532,00€100mg745,00€1mL*10mM (DMSO)154,00€Efonidipine
CAS :Efonidipine (NZ-105)(NZ-105) is a dihydropyridine calcium channel blocker, blocking both T-type and L-type calcium channels.Formule :C34H38N3O7PDegré de pureté :98.35% - 99.47%Couleur et forme :SolidMasse moléculaire :631.66Cycleanine
CAS :Cycleanine has potent antibacterial, antifungal, antiplasmodial, and cytotoxic activities.Formule :C38H42N2O6Degré de pureté :98.04% - 99.57%Couleur et forme :SolidMasse moléculaire :622.75Bepridil hydrochloride
CAS :Bepridil hydrochloride (CERM 1978) is a calcium channel blocker and also inhibits Na+/Ca2+ exchange (NCX), sodium channels and cardiac sarcolemmal KATP channelsFormule :C24H35ClN2ODegré de pureté :99.45% - 99.68%Couleur et forme :SolidMasse moléculaire :403Efonidipine hydrochloride
CAS :Efonidipine HCl (NZ-105) blocks T-type/L-type calcium channels; used in hypertension treatment.Formule :C34H39ClN3O7PCouleur et forme :SolidMasse moléculaire :668.12o-3M3FBS
CAS :O-3M3FBS is an inactive analog of m-3M3FBS (PLC activator).Formule :C16H16F3NO2SDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :343.36Ref: TM-T23101
2mg40,00€5mg57,00€10mg84,00€25mg166,00€50mg259,00€100mg380,00€200mg557,00€1mL*10mM (DMSO)67,00€Levamlodipine hydrochloride
CAS :Levamlodipine hydrochloride is a medication used to lower blood pressure and prevent chest pain.Formule :C20H26Cl2N2O5Couleur et forme :SolidMasse moléculaire :445.342,5-Di-tert-butylhydroquinone
CAS :2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.Formule :C14H22O2Degré de pureté :97.11%Couleur et forme :PelletslargecrystalsMasse moléculaire :222.32Propiverine hydrochloride
CAS :Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB).Formule :C23H30ClNO3Degré de pureté :99.93%Couleur et forme :White Crystalling PowerMasse moléculaire :403.94DHBP dibromide
CAS :DHBP dibromide (1,1'-DI-N-HEPTYL-4,4'-BIPYRIDINIUM DIBRO) is calcium release and a muscle relaxant inhibitor.Formule :C24H38Br2N2Degré de pureté :99.73%Couleur et forme :Yellow To Yellow-Green Powder Or FlakesMasse moléculaire :514.38L-Phenylalanine-15N
CAS :L-Phenylalanine-15N, essential amino acid, Ca+ channel and NMDARs antagonist, used in food flavors and pharmaceuticals.Formule :C9H11NO2Degré de pureté :98.98%Couleur et forme :SolidMasse moléculaire :166.18TTA-A2
CAS :TTA-A2: T-type calcium channel blocker; anticonvulsant targeting Cav3.1, Cav3.2; IC50 of 89/92 nM; potential for treating neurological conditions.Formule :C20H21F3N2O2Degré de pureté :99.5% - 99.9%Couleur et forme :SolidMasse moléculaire :378.39Ref: TM-T8944
1mg99,00€5mg241,00€10mg385,00€25mg707,00€50mg1.009,00€100mg1.333,00€1mL*10mM (DMSO)265,00€CALP3 acetate(261969-05-5 free base)
CALP3 acetate blocks Ca2+ channels, mimics elevated [Ca2+]i, activates EF hands, and regulates CaM, channels, and pumps.Formule :C46H72N10O11Degré de pureté :96.49%Couleur et forme :SolidMasse moléculaire :941.12GSK1016790A
CAS :GSK1016790A (GSK101) (GSK101) is a novel, potent activator of TRPV4 (transient receptor potential vanilloid 4) with EC50 of 34 nM in choroid plexus epithelialFormule :C28H32Cl2N4O6S2Degré de pureté :97.37% - 99.38%Couleur et forme :SolidMasse moléculaire :655.61Ref: TM-T6848
1mg34,00€2mg46,00€5mg69,00€10mg107,00€25mg227,00€50mg344,00€100mg512,00€1mL*10mM (DMSO)92,00€Gabapentin hydrochloride
CAS :Gabapentin hydrochloride (Neurontin HCl) is a GABA analogue, used to treat seizures and neuropathic pain.Formule :C9H17NO2·HClDegré de pureté :99.71%Couleur et forme :Off-White SolidMasse moléculaire :207.7Bifemelane
CAS :Bifemelane, a nootropic, releases Ca2+ from stores and enables its entry via channels for astrocyte research.Formule :C18H23NOCouleur et forme :SolidMasse moléculaire :269.38(+)-Kavain
CAS :(+)-Kavain ((R)-KAWAIN) is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.Formule :C14H14O3Degré de pureté :97% - ≥95%Couleur et forme :White Fine PowderMasse moléculaire :230.26(±)-Praeruptorin A
CAS :(±)-Praeruptorin A could exhibit its anti-osteoclastogenic activity by inhibiting p38/Akt-c-Fos-NFATc1 signaling and PLCγ-independent Ca(2+) oscillation.Formule :C21H22O7Degré de pureté :98.9% - 99.73%Couleur et forme :SolidMasse moléculaire :386.40Ethacrynic acid
CAS :Ethacrynic acid (Edecrin) 是谷胱甘肽 S-转移酶抑制剂，也是NF-κB 信号传导途径的有效抑制剂，并且还调节白三烯的形成。它还可抑制 L 型电压依赖性和储存操作的钙通道，从而导致气道平滑肌细胞松弛。它是利尿剂，具有抗炎特性，可减轻类维生素 A 诱导的小鼠耳部水肿。Formule :C13H12Cl2O4Degré de pureté :98.61% - 99.85%Couleur et forme :Crystals Physical Description White Solid (Ntp 1992)Masse moléculaire :303.14HALOFUGINONE LACTATE
CAS :HALOFUGINONE LACTATE is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D.Formule :C19H23BrClN3O6Degré de pureté :99.70% - 99.96%Couleur et forme :SolidMasse moléculaire :504.8Ref: TM-T8785
2mg39,00€5mg56,00€10mg89,00€25mg123,00€50mg197,00€100mg294,00€200mg437,00€1mL*10mM (DMSO)63,00€Dantrolene sodium hemiheptahydrate
CAS :Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1 and decreasing intracellular calciumFormule :C14H9N4NaO5·5H2ODegré de pureté :99.72%Couleur et forme :Orange PowderMasse moléculaire :399.29NS-638
CAS :NS-638 is a Ca2+-channel blocker. It can block K+-stimulated intracellular Ca2+-elevation (IC50: 3.4 μM).Formule :C15H11ClF3N3Degré de pureté :98.44%Couleur et forme :SolidMasse moléculaire :325.72Azumolene
CAS :Azumolene (EU4093 free base)Formule :C13H9BrN4O3Degré de pureté :98.1% - 98.35%Couleur et forme :SolidMasse moléculaire :349.14Ref: TM-T8815
2mg47,00€5mg70,00€10mg110,00€25mg222,00€50mg353,00€100mg532,00€500mg1.153,00€1mL*10mM (DMSO)78,00€TGR5 Receptor Agonist
CAS :TGR5 is a potent TGR5(GPCR19) agonist.Formule :C18H14Cl2N2O2Degré de pureté :99.77% - ≥95%Couleur et forme :SolidMasse moléculaire :361.22Suvecaltamide
CAS :Suvecaltamide (MK-8998) as potent inhibitors of T-type calcium channels.Formule :C20H23F3N2O2Degré de pureté :99.29% - 99.70%Couleur et forme :SolidMasse moléculaire :380.4NFAT Inhibitor-2
CAS :NFAT Inhibitor-2 is a compound used as a molecular building block.Formule :C22H20F2N2O4SDegré de pureté :97.37%Couleur et forme :SolidMasse moléculaire :446.47Myomodulin acetate(110570-93-9 free base)
Myomodulin acetate is present in two identified aplysia neurons that contain myomodulin A the ARC motor neuron B16 and the abdominal neuron L10.Formule :C38H71N11O10S2Degré de pureté :99.24%Couleur et forme :SolidMasse moléculaire :906.17m-Nisoldipine
CAS :m-Nisoldipine, a nisoldipine derivative, is a dihydropyridine that treats hypertension and angina by blocking L-type calcium channels.Formule :C20H24N2O6Degré de pureté :95.00%Couleur et forme :SolidMasse moléculaire :388.41Ref: TM-T50077
1mg79,00€5mg163,00€10mg235,00€25mg389,00€50mg532,00€100mg745,00€200mg982,00€1mL*10mM (DMSO)172,00€ABT-639 hydrochloride
CAS :ABT-639 hydrochloride is a selective, novel T-type Ca2+ channel blocker.Formule :C20H21Cl2F2N3O3SCouleur et forme :SolidMasse moléculaire :492.36Bepridil free base
CAS :Bepridil: Class IV anti-arrhythmic, calcium blocker, dilates coronary arteries.Formule :C24H34N2OCouleur et forme :SolidMasse moléculaire :366.54NP118809
CAS :NP118809 (39-1B4) is a potent N-type calcium channel blocker(IC50 : 0.11 μM).
Formule :C32H32N2ODegré de pureté :97.74% - 98.68%Couleur et forme :SolidMasse moléculaire :460.61L-Phenylalanine
CAS :L-Phenylalanine (3-Phenyl-L-alanine) is an essential amino acid and the precursor of the amino acid tyrosine, acts as an antagonist at α2δ calcium channels.Formule :C9H11NO2Degré de pureté :99.37% - 99.87%Couleur et forme :Solid CrystallineMasse moléculaire :165.19Efonidipine hydrochloride monoethanolate
CAS :Efonidipine HCl monoethanolate is a calcium blocker, boosts dehydroepiandrosterone sulfate in NCI-H295R cells.Formule :C36H45ClN3O8PDegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :714.18Ibutilide Fumarate
CAS :Ibutilide Fumarate is a class III antiarrhythmic, prolonging action potentials by enhancing sodium influx, and can extend QT interval.Formule :(C20H36N2O3S)2·C4H4O4Degré de pureté :99.68% - 99.74%Couleur et forme :SolidMasse moléculaire :885.23Gomisin J
CAS :Gomisin J is a natural product and have vasodilatory activity.Formule :C22H28O6Degré de pureté :99.59% - 99.60%Couleur et forme :SolidMasse moléculaire :388.45Ref: TM-T3904
1mg44,00€2mg62,00€5mg113,00€10mg178,00€25mg313,00€50mg465,00€100mg662,00€1mL*10mM (DMSO)92,00€HA-1004 HCl
CAS :HA-1004 is an inhibitor of PKA, cGKI, PKC, MYLK, and calcium channel protein.Formule :C12H17Cl2N5O2SCouleur et forme :SolidMasse moléculaire :366.27HC-056456
CAS :HC-056456 (3,4-Bis(2-thienoyl)-1,2,5-oxadiazole-N-oxide) is a CatSper channel modulator.Formule :C12H6N2O4S2Degré de pureté :99.62% - 99.65%Couleur et forme :SolidMasse moléculaire :306.32Ref: TM-T4604
1mg34,00€2mg46,00€5mg66,00€10mg90,00€25mg166,00€50mg260,00€100mg430,00€1mL*10mM (DMSO)73,00€Levamlodipine hydrobromide
CAS :Levamlodipine hydrobromide is a medication used to lower blood pressure and prevent chest pain.Formule :C20H26BrClN2O5Couleur et forme :SolidMasse moléculaire :489.79Psoralenoside
CAS :Psoralenoside: a compound from Psoralea fruit; has estrogenic, osteoblastic, antitumor, and antibacterial properties.Formule :C17H18O9Degré de pureté :99.03% - 99.49%Couleur et forme :SolidMasse moléculaire :366.32Ref: TM-TN1008
1mg90,00€2mg132,00€5mg215,00€10mg344,00€25mg568,00€50mg800,00€100mg1.063,00€1mL*10mM (DMSO)222,00€VK-II-36
CAS :VK-II-36, a carvedilol analog, suppresses sarcoplasmic reticulum (SR) Ca(2+) release but does not block the β-receptor.Formule :C26H26N2O5Degré de pureté :99.12%Couleur et forme :SolidMasse moléculaire :446.49CDN1163
CAS :CDN1163 is a small molecule activator of sarco/endoplasmic reticulum Ca2+-ATPase (SERCA).Formule :C20H20N2O2Degré de pureté :99.83% - ≥95%Couleur et forme :SolidMasse moléculaire :320.39Ref: TM-T7373
2mg39,00€5mg57,00€10mg93,00€25mg152,00€50mg236,00€100mg385,00€200mg560,00€1mL*10mM (DMSO)63,00€ABT-639
CAS :ABT-639 is a potent and selective T-type calcium channel blocker.Formule :C20H20ClF2N3O3SDegré de pureté :99.12% - 99.77%Couleur et forme :SolidMasse moléculaire :455.91Ref: TM-T3703
2mg34,00€5mg49,00€10mg75,00€25mg160,00€50mg268,00€100mg444,00€200mg647,00€1mL*10mM (DMSO)60,00€Praeruptorin C
CAS :Praeruptorin C: an antioxidant, calcium antagonist, protects neurons, reduces vascular hypertrophy, affects cellular signals.
Formule :C24H28O7Degré de pureté :99.6% - 99.92%Couleur et forme :SolidMasse moléculaire :428.47
