Canal calcique
Les canaux calciques sont des protéines membranaires qui régulent le flux d'ions calcium dans et hors des cellules, ce qui est essentiel pour diverses fonctions cellulaires, y compris la contraction musculaire, la libération de neurotransmetteurs et l'expression génique. La dysrégulation de l'activité des canaux calciques est associée à des conditions telles que l'hypertension, les arythmies cardiaques et les troubles neurologiques. Chez CymitQuimica, nous proposons une large sélection de modulateurs des canaux calciques pour soutenir vos recherches en santé cardiovasculaire, neurobiologie et transduction du signal.
573 produits trouvés pour "Canal calcique"
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Mirogabalin besylate
CAS :Mirogabalin besylate is an oral α2δ ligand for voltage-gated calcium channels, with Kd values of 13.5-47.6 nM across species.Formule :C18H25NO5SCouleur et forme :SolidMasse moléculaire :367.46ABT-639
CAS :ABT-639 is a potent and selective T-type calcium channel blocker.Formule :C20H20ClF2N3O3SDegré de pureté :99.12% - 99.77%Couleur et forme :SolidMasse moléculaire :455.91Ref: TM-T3703
2mg34,00€5mg49,00€10mg75,00€25mg160,00€50mg268,00€100mg444,00€200mg647,00€1mL*10mM (DMSO)60,00€Mibefradil dihydrochloride
CAS :Mibefradil dihydrochloride (Ro 40-5967 (dihydrochloride)) is an blocker of calcium channel with moderate selectivity for T-type Ca2+ channels (T-type and L-typeFormule :C29H40Cl2FN3O3Degré de pureté :99.45% - 99.91%Couleur et forme :SolidMasse moléculaire :568.55L-Phenylalanine-15N
CAS :L-Phenylalanine-15N, essential amino acid, Ca+ channel and NMDARs antagonist, used in food flavors and pharmaceuticals.Formule :C9H11NO2Degré de pureté :98.98%Couleur et forme :SolidMasse moléculaire :166.18VK-II-36
CAS :VK-II-36, a carvedilol analog, suppresses sarcoplasmic reticulum (SR) Ca(2+) release but does not block the β-receptor.Formule :C26H26N2O5Degré de pureté :99.12%Couleur et forme :SolidMasse moléculaire :446.49Ranolazine
CAS :Ranolazine (RS 43285-003) inhibits calcium uptake, treats chronic angina by targeting sodium/calcium channels to modulate intracellular sodium.Formule :C24H33N3O4Degré de pureté :98.13%Couleur et forme :White SolidMasse moléculaire :427.54Mirogabalin
CAS :Mirogabalin (DS5565) is a calcium channel blocker with analgesic effects.Formule :C12H19NO2Degré de pureté :98.57%Couleur et forme :SolidMasse moléculaire :209.28NP118809
CAS :NP118809 (39-1B4) is a potent N-type calcium channel blocker(IC50 : 0.11 μM).
Formule :C32H32N2ODegré de pureté :97.74% - 98.68%Couleur et forme :SolidMasse moléculaire :460.61Pyr6
CAS :Pyr6 (N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-4-pyridinecarboxamide) is a selective TRPC3 inhibitor with IC50 of 0.49 uM(Ca2+ influxFormule :C17H9F7N4ODegré de pureté :98.89%Couleur et forme :SolidMasse moléculaire :418.27Quadrol
CAS :Quadrol (EDTP) is an immunostimulant, accelerated wound healing.Formule :C14H32N2O4Degré de pureté :99.91% - 99.92%Couleur et forme :Viscous Liquid Liquid ViscousMasse moléculaire :292.41S107
CAS :S107 stabilizes RyR2 by improving calstabin2 binding to mutant/PKA-phosphorylated channels.Formule :C11H15NOSDegré de pureté :99.90%Couleur et forme :SolidMasse moléculaire :209.31Ref: TM-T3438
2mg35,00€5mg60,00€10mg92,00€25mg149,00€50mg241,00€100mg344,00€200mg489,00€1mL*10mM (DMSO)66,00€Argireline
CAS :Argireline (Acetyl hexapeptide-3) is a peptide that inhibits neurotransmitter release, reducing wrinkles.Formule :C34H60N14O12SDegré de pureté :96.79% - 99.65%Couleur et forme :White PowderMasse moléculaire :888.99Praeruptorin E
CAS :Praeruptorin C/E relaxes arteries, reduces heart contractility, acting like calcium blockers. D/E protect mice from acid lung injury by halting PMNs and IL-6.Formule :C24H28O7Degré de pureté :98.04% - 99.95%Couleur et forme :SolidMasse moléculaire :428.47SR33805
CAS :SR33805 is a potent antagonist of Ca2+ channel(EC50s of 4.1 nM and 33 nM in depolarized and polarized conditions, respectively)Formule :C32H40N2O5SDegré de pureté :99.15%Couleur et forme :SolidMasse moléculaire :564.74Ref: TM-T8674
1mg34,00€5mg64,00€10mg96,00€25mg170,00€50mg250,00€100mg354,00€200mg484,00€1mL*10mM (DMSO)80,00€Levamlodipine hydrobromide
CAS :Levamlodipine hydrobromide is a medication used to lower blood pressure and prevent chest pain.Formule :C20H26BrClN2O5Couleur et forme :SolidMasse moléculaire :489.79HA-1004 HCl
CAS :HA-1004 is an inhibitor of PKA, cGKI, PKC, MYLK, and calcium channel protein.Formule :C12H17Cl2N5O2SCouleur et forme :SolidMasse moléculaire :366.27L-Phenylalanine
CAS :L-Phenylalanine (3-Phenyl-L-alanine) is an essential amino acid and the precursor of the amino acid tyrosine, acts as an antagonist at α2δ calcium channels.Formule :C9H11NO2Degré de pureté :99.37% - 99.87%Couleur et forme :Solid CrystallineMasse moléculaire :165.19Azumolene
CAS :Azumolene (EU4093 free base)Formule :C13H9BrN4O3Degré de pureté :98.1% - 98.35%Couleur et forme :SolidMasse moléculaire :349.14Ref: TM-T8815
2mg47,00€5mg70,00€10mg110,00€25mg222,00€50mg353,00€100mg532,00€500mg1.153,00€1mL*10mM (DMSO)78,00€NFAT Inhibitor-2
CAS :NFAT Inhibitor-2 is a compound used as a molecular building block.Formule :C22H20F2N2O4SDegré de pureté :97.37%Couleur et forme :SolidMasse moléculaire :446.47Dantrolene sodium hemiheptahydrate
CAS :Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1 and decreasing intracellular calciumFormule :C14H9N4NaO5·5H2ODegré de pureté :99.72%Couleur et forme :Orange PowderMasse moléculaire :399.29HALOFUGINONE LACTATE
CAS :HALOFUGINONE LACTATE is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D.Formule :C19H23BrClN3O6Degré de pureté :99.70% - 99.96%Couleur et forme :SolidMasse moléculaire :504.8Ref: TM-T8785
2mg39,00€5mg56,00€10mg89,00€25mg123,00€50mg197,00€100mg294,00€200mg437,00€1mL*10mM (DMSO)63,00€Ethacrynic acid
CAS :Ethacrynic acid (Edecrin) 是谷胱甘肽 S-转移酶抑制剂，也是NF-κB 信号传导途径的有效抑制剂，并且还调节白三烯的形成。它还可抑制 L 型电压依赖性和储存操作的钙通道，从而导致气道平滑肌细胞松弛。它是利尿剂，具有抗炎特性，可减轻类维生素 A 诱导的小鼠耳部水肿。Formule :C13H12Cl2O4Degré de pureté :98.61% - 99.85%Couleur et forme :Crystals Physical Description White Solid (Ntp 1992)Masse moléculaire :303.14CALP3 acetate(261969-05-5 free base)
CALP3 acetate blocks Ca2+ channels, mimics elevated [Ca2+]i, activates EF hands, and regulates CaM, channels, and pumps.Formule :C46H72N10O11Degré de pureté :96.49%Couleur et forme :SolidMasse moléculaire :941.12Gabapentin hydrochloride
CAS :Gabapentin hydrochloride (Neurontin HCl) is a GABA analogue, used to treat seizures and neuropathic pain.Formule :C9H17NO2·HClDegré de pureté :99.71%Couleur et forme :Off-White SolidMasse moléculaire :207.7m-Nisoldipine
CAS :m-Nisoldipine, a nisoldipine derivative, is a dihydropyridine that treats hypertension and angina by blocking L-type calcium channels.Formule :C20H24N2O6Degré de pureté :95.00%Couleur et forme :SolidMasse moléculaire :388.41Ref: TM-T50077
1mg79,00€5mg163,00€10mg235,00€25mg389,00€50mg532,00€100mg745,00€200mg982,00€1mL*10mM (DMSO)172,00€Cycleanine
CAS :Cycleanine has potent antibacterial, antifungal, antiplasmodial, and cytotoxic activities.Formule :C38H42N2O6Degré de pureté :98.04% - 99.57%Couleur et forme :SolidMasse moléculaire :622.75o-3M3FBS
CAS :O-3M3FBS is an inactive analog of m-3M3FBS (PLC activator).Formule :C16H16F3NO2SDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :343.36Ref: TM-T23101
2mg40,00€5mg57,00€10mg84,00€25mg166,00€50mg259,00€100mg380,00€200mg557,00€1mL*10mM (DMSO)67,00€RO2959 Hydrochloride
CAS :RO2959 Hydrochloride (RO2959 HCl) is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.Formule :C21H20ClF2N5OSDegré de pureté :99.24%Couleur et forme :SolidMasse moléculaire :463.93Pranidipine
CAS :Pranidipine (OPC-13340) is a novel, long-acting 1,4-dihydropyridine calcium channel blocker.Formule :C25H24N2O6Degré de pureté :99.95%Couleur et forme :Yellow SolidMasse moléculaire :448.47Glaucine
CAS :Glaucine: antitussive, antioxidative, antiviral, may fight arthritis, boosts IL-10, hinders breast cancer cell spread by inhibiting MMP-9 and NF-κB.
Formule :C21H25NO4Degré de pureté :99.42% - 99.56%Couleur et forme :SolidMasse moléculaire :355.43Aranidipine
CAS :Aranidipine (MPC1304) (MPC1304) is a calcium channel antagonist with potent and long-lasting antihypertensive effects.Formule :C19H20N2O7Degré de pureté :99.15%Couleur et forme :SolidMasse moléculaire :388.37Myomodulin acetate(110570-93-9 free base)
Myomodulin acetate is present in two identified aplysia neurons that contain myomodulin A the ARC motor neuron B16 and the abdominal neuron L10.Formule :C38H71N11O10S2Degré de pureté :99.24%Couleur et forme :SolidMasse moléculaire :906.17TTA-A2
CAS :TTA-A2: T-type calcium channel blocker; anticonvulsant targeting Cav3.1, Cav3.2; IC50 of 89/92 nM; potential for treating neurological conditions.Formule :C20H21F3N2O2Degré de pureté :99.5% - 99.9%Couleur et forme :SolidMasse moléculaire :378.39Ref: TM-T8944
1mg99,00€5mg241,00€10mg385,00€25mg707,00€50mg1.009,00€100mg1.333,00€1mL*10mM (DMSO)265,00€Gomisin J
CAS :Gomisin J is a natural product and have vasodilatory activity.Formule :C22H28O6Degré de pureté :99.59% - 99.60%Couleur et forme :SolidMasse moléculaire :388.45Ref: TM-T3904
1mg44,00€2mg62,00€5mg113,00€10mg178,00€25mg313,00€50mg465,00€100mg662,00€1mL*10mM (DMSO)92,00€Fasudil hydrochloride
CAS :Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.Formule :C14H18ClN3O2SDegré de pureté :99.54% - ≥95%Couleur et forme :White SolidMasse moléculaire :327.83Norfluoxetine Hydrochloride
CAS :Norfluoxetine Hydrochloride (Norfluoxetine HCl) is an active metabolite of fluoxetine. Fluoxetine is an antidepressant drug.Formule :C16H17ClF3NODegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :331.76Lanthanum(III) chloride heptahydrate
CAS :Lanthanum(III) chloride blocks divalent cation channels, useful for biochemical research.Formule :Cl3H14LaO7Degré de pureté :98%Couleur et forme :White Solid PowderMasse moléculaire :371.37Ref: TM-T22353
5mg46,00€10mg59,00€25mg87,00€50mg129,00€100mg178,00€200mg268,00€500mg460,00€1mL*10mM (DMSO)52,00€Barnidipine hydrochloride
CAS :Barnidipine HCl is a potent dihydropyridine Ca²⁺ blocker with 0.35 nM IC50 in pig coronary artery.Formule :C27H30ClN3O6Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :528Manidipine
CAS :Manidipine (Iperten), a calcium channel blocker, which is dihydropyridine type. It is utilizedFormule :C35H38N4O6Degré de pureté :99.30%Couleur et forme :SolidMasse moléculaire :610.7Heteroclitin D
CAS :1. Heteroclitin D can inhibit L-type calcium channels. 2. Heteroclitin D might be a valuable antitumor promoter or chemopreventor.Formule :C27H30O8Degré de pureté :99.24% - 99.91%Couleur et forme :SolidMasse moléculaire :482.52Ref: TM-T3S1916
1mg62,00€5mg166,00€10mg239,00€25mg388,00€50mg533,00€100mg718,00€200mg964,00€1mL*10mM (DMSO)182,00€ISX-9
CAS :ISX-9 (Isoxazole 9) is necessary to activate neuron-specific genes as neurogenesis inducer.Formule :C11H10N2O2SDegré de pureté :97.81% - ≥95%Couleur et forme :SolidMasse moléculaire :234.27Ref: TM-T2003
2mg48,00€5mg72,00€10mg97,00€25mg155,00€50mg210,00€100mg378,00€500mg889,00€1mL*10mM (DMSO)79,00€YM-58483
CAS :YM-58483 (BTP2) is a specific and effective inhibitor of CRAC channels and subsequent Ca2+ signals.Formule :C15H9F6N5OSDegré de pureté :99.33% - 99.64%Couleur et forme :SolidMasse moléculaire :421.32Ref: TM-T3651
1mg34,00€2mg48,00€5mg71,00€10mg109,00€25mg215,00€50mg364,00€100mg532,00€1mL*10mM (DMSO)65,00€Z944
CAS :Z944 is a T-type calcium channel blocker.Formule :C19H27ClFN3O2Degré de pureté :99.8% - 99.80%Couleur et forme :SolidMasse moléculaire :383.89Ref: TM-T29201
1mg50,00€5mg105,00€10mg170,00€25mg340,00€50mg502,00€100mg718,00€200mg982,00€1mL*10mM (DMSO)117,00€Barnidipine
CAS :Barnidipine (YM-09730-5(Free base)) is a calcium channel blocker.Formule :C27H29N3O6Degré de pureté :99.98%Couleur et forme :SolidMasse moléculaire :491.54Ref: TM-T7550
1mg46,00€2mg57,00€5mg89,00€10mg123,00€25mg230,00€50mg344,00€100mg520,00€1mL*10mM (DMSO)97,00€Ginsenoside Rf
CAS :Ginsenoside Rf (Panaxoside Rf) is a trace component of ginseng root. Ginsenoside Rf inhibits N-type Ca2+ channel.Formule :C42H72O14Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :801.01Urolithin C
CAS :Urolithin C is a gut metabolite of ellagic acid. Urolithin C induces apoptosis in PC12 cells through a mitochondria-mediated pathway.Formule :C13H8O5Degré de pureté :98.01% - 99.53%Couleur et forme :SolidMasse moléculaire :244.2Ref: TM-TN7108
5mg50,00€10mg84,00€25mg136,00€50mg222,00€100mg334,00€200mg495,00€500mg782,00€1mL*10mM (DMSO)56,00€Ginsenoside Ro
CAS :Ginsenoside Ro (Chikusetsusaponin V) can reduce TXA2 production, weakly reduce COX-1 and TXAS activities, and has antiplatelet effects as a Ca2+ antagonist withFormule :C48H76O19Degré de pureté :98% - 99.66%Couleur et forme :SolidMasse moléculaire :957.11Isradipine
CAS :Isradipine (PN 200-110), a dihydropyridine, is an antihypertensive calcium channel blocker that dilates arteries and reduces resistance.Formule :C19H21N3O5Degré de pureté :99.84% - 99.95%Couleur et forme :Yellow SolidMasse moléculaire :371.39Ruthenium Red
CAS :Ruthenium Red (Ammoniated ruthenium oxychloride) is a polycationic dye widely used for electron microscopy (EM) of cells, tissues and vegetative bacteria.Formule :Cl6H42N14O2Ru3Degré de pureté :95%Couleur et forme :Purple PowderMasse moléculaire :786.34Benidipine hydrochloride
CAS :Benidipine hydrochloride (Coniel) , a hydrochloride salt form of benidipine, is used as a blocker of dihydropyridine calcium channel.Formule :C28H32ClN3O6Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :542.03
