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PDE

PDE

Les phosphodiestérases (PDE) sont des enzymes qui hydrolysent les nucléotides cycliques, tels que l'AMPc et le GMPc, en leurs formes inactives, jouant un rôle clé dans la régulation des voies de signalisation intracellulaire. Les inhibiteurs de PDE sont utilisés dans le traitement de diverses affections, notamment les maladies cardiovasculaires, la dysfonction érectile et les troubles respiratoires, en raison de leur capacité à moduler les niveaux de nucléotides cycliques. Chez CymitQuimica, nous proposons une gamme d'inhibiteurs de PDE pour soutenir vos recherches en signalisation cellulaire, pharmacologie et développement thérapeutique.

202 produits trouvés pour "PDE".

produits par page.
  • Acetildenafil

    CAS :
    Acetildenafil is an analog of the phosphodiesterase inhibitor sildenafil.
    Formule :C25H34N6O3
    Couleur et forme :Off-White To Pale Yelow Solid
    Masse moléculaire :466.5759
  • PDE4B-IN-6


    PDE4B-IN-6 is a highly selective PDE4B inhibitor (IC50=7.42 nM) that exerts anti-inflammatory effects by elevating cAMP and inhibiting TNF-α, used in COPD research.
    Formule :C22H24F2N2O7
    Degré de pureté :99.20%
    Masse moléculaire :466.43
  • Acetildenafil (Standard)

    CAS :
    Acetildenafil (Hongdenafil) (Standard) is the standard substance of Acetildenafil (Hongdenafil), and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Acetildenafil is an analog of the phosphodiesterase inhibitor sildenafil.
    Formule :C25H34N6O3
    Masse moléculaire :466.5759
  • Nor-acetildenafil (Standard)

    CAS :
    Nor-acetildenafil (Standard) is the standard substance of Nor-acetildenafil, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Nor-Acetildenafil is a derivative of Acetildenafil, a synthetic phosphodiesterase inhibitor.
    Formule :C24H32N6O3
    Masse moléculaire :452.5493
  • Autotaxin modulator 1

    CAS :
    Autotaxin modulator 1 is a new modulator of Autotaxin.
    Formule :C28H31F6NO3
    Degré de pureté :99.46%
    Couleur et forme :White Solid
    Masse moléculaire :543.5411
  • PF-05180999

    CAS :
    α-2,3-sialyltransferase-IN-1 (Lith-O-Asp analog) is an α-2,3-sialyltransferase inhibitor with anticancer activity.
    Formule :C19H17F3N8
    Degré de pureté :99.43% - 99.82%
    Couleur et forme :Solid
    Masse moléculaire :414.3871
  • UK 088800 (Standard)

    CAS :
    UK 088800 (Standard) is the standard substance of UK 088800, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. UK 088800 is a bioacitve chemical
    Formule :C17H20N4O2
    Masse moléculaire :312.3663
  • PF-05085727

    CAS :
    PF-05085727 inhibits PDE2A >4,000-fold selectivity over PDE1 and PDE3-11.
    Formule :C20H18F3N7
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :413.399
  • Udenafil (Standard)

    CAS :
    Udenafil (Standard) is the standard substance of Udenafil, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Udenafil is an inhibitor of PDE5 .
    Formule :C25H36N6O4S
    Masse moléculaire :516.656
  • Tadalafil-D3

    CAS :
    Tadalafil-D3 is a deuterated compound of Tadalafil. Tadalafil (T1398) has a CAS number of 171596-29-5. Tadalafil (T1398) is a carboline-based compound with vasodilatory activity. Tadalafil (T1398) selectively inhibits the cyclic guanosine monophosphate (cGMP)-specific type 5 phosphodiesterase- (PDE-5)-mediated degradation of cGMP, which is found in the smooth muscle of the corpus cavernosa and corpus spongiosum of the penis. Inhibition of cGMP degradation by tadalafil results in prolonged muscle relaxation, vasodilation, and blood engorgement of the corpus cavernosa, and, so, prolonged penile erection.
    Formule :C22H19N3O4
    Masse moléculaire :392.4224
  • DNMDP

    CAS :
    DNMDP is a potent and selective PDE3A inhibitor with anticancer activity. It binds to PDE3A, promoting its interaction with Schlafen 12 (SLFN12).
    Formule :C15H20N4O3
    Couleur et forme :Orange Solid
    Masse moléculaire :304.3443
  • Bay 60-7550

    CAS :
    Bay 60-7550 is a PDE2 inhibitor that exerts positive inotropic effects in the rat heart by increasing PKA-mediated phosphorylation.
    Formule :C27H32N4O4
    Degré de pureté :98.14%
    Couleur et forme :Solid
    Masse moléculaire :476.5674
  • ALDH7A1 Protein, Human, Recombinant (His)


    ALDH7A1 (Aldehyde dehydrogenase 7 family, member A1) is a member of subfamily 7 in the aldehyde dehydrogenase family.
    Couleur et forme :Transparent Liquid
    Masse moléculaire :56 kDa (predicted); 56 kDa (reducing conditions)
  • BAY 73-6691 racemate

    CAS :
    BAY 73-6691 racemate (Rac-BAY 73-6691) is a phosphodiesterase 9A (PDE9A) inhibitor, useful for studying Parkinson’s disease.
    Formule :C15H12ClF3N4O
    Couleur et forme :White Solid
    Masse moléculaire :356.73
  • Anti-ALDH7A1 Antibody-FITC (5P692)


    Anti-ALDH7A1 Antibody-FITC (5P692) is a FITC-conjugated Rabbit antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody-FITC (5P692) can be used in FCM.
    Couleur et forme :Odour Liquid
  • Anti-ALDH7A1 Antibody (6G475)


    Anti-ALDH7A1 Antibody (6G475) is a Mouse antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (6G475) can be used in IHC-P.
    Couleur et forme :Odour Liquid
  • ENPP1 Inhibitor C

    CAS :
    ML-354 (VU0099704) is an antagonist with and PAR4 for the study of cardiovascular diseases.
    Formule :C15H18N6
    Degré de pureté :99.28%
    Couleur et forme :Yellow Viscous
    Masse moléculaire :282.3436
  • Anti-ALDH7A1 Antibody (3P955)


    Anti-ALDH7A1 Antibody (3P955) is a Rabbit antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (3P955) can be used in WB,ELISA,IP.
    Couleur et forme :Odour Liquid
  • Anti-ALDH7A1 Antibody (5P692)


    Anti-ALDH7A1 Antibody (5P692) is a Rabbit antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (5P692) can be used in FCM,ICC/IF.
    Couleur et forme :Odour Liquid
  • N-Ethyl tadalafil

    CAS :
    N-Ethyl tadalafil (NEthyl tadalafil) is a PDE inhibitor used in the study of cardiovascular disease.
    Formule :C23H21N3O4
    Degré de pureté :99.58%
    Couleur et forme :Solid
    Masse moléculaire :403.43