Aminopeptidase
Les aminopeptidases sont un groupe d'enzymes qui catalysent la coupure des acides aminés à partir de l'extrémité N-terminale des peptides et des protéines, jouant un rôle crucial dans la maturation et la dégradation des protéines. Ces enzymes sont impliquées dans divers processus physiologiques, notamment le traitement des antigènes, la régulation des hormones peptidiques et l'homéostasie cellulaire. Les inhibiteurs des aminopeptidases présentent un intérêt pour le traitement de maladies telles que le cancer, l'inflammation et les maladies infectieuses. Chez CymitQuimica, nous proposons une variété d'inhibiteurs d'aminopeptidases pour soutenir vos recherches en protéomique, développement de médicaments et traitement des maladies.
67 produits trouvés pour "Aminopeptidase"
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ERAP1-IN-1
CAS :<p>ERAP1-IN-1 inhibits and allosterically activates ERAP1, affecting fluorogenic, chromogenic, and nonamer peptide substrates.</p>Formule :C20H21F3N2O5SDegré de pureté :98.95%Couleur et forme :SolidMasse moléculaire :458.45Bufexamac
CAS :<p>Bufexamac (Bufexamic acid) is a COX inhibitor for IFN-α release with anti-inflammatory, analgesic, and antipyretic action.</p>Formule :C12H17NO3Degré de pureté :99.73%Couleur et forme :Acicular CrystalMasse moléculaire :223.27Probestin
CAS :<p>Probestin is an aminopeptidase M inhibitor, isolated from Streptomyces azureus MH663-2F6.</p>Formule :C26H38N4O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :502.60Aminopeptidase N inhibitor 2
<p>AminopeptidaseN inhibitor 2 is an APN inhibitor (IC50: 4.3 μM) with antitumor properties.</p>Formule :C12H16F2N2O4SCouleur et forme :SolidMasse moléculaire :322.07988BAY-277
<p>BAY-277 is a degrader of METAP2, with IC50 values of 5.8 nM for human METAP2 (hMETAP2) and 5.9 nM for mouse METAP2 (mMETAP2).</p>Formule :C44H52N8O5Couleur et forme :SolidMasse moléculaire :772.93LTA4H-IN-4
<p>LTA4H-IN-4 (compound 3) is an orally active inhibitor of LTA4H. It exhibits an IC50 value of 156 μM against hERG and is applicable for inflammation-related research.</p>Leuhistin
CAS :Leuhistin is an aminopeptidases N inhibitor isolated from Bacillus laterosporus BMI156-14F1.Formule :C11H19N3O3Degré de pureté :98%Couleur et forme :White To Off-White SolidMasse moléculaire :241.29Matlystatin A
CAS :<p>Matlystatin A is an inhibitor of aminopeptidase. It shows multiple inhibitory activities against both aminopeptidase N and matrix metalloproteinases.</p>Formule :C27H47N5O8SCouleur et forme :SolidMasse moléculaire :601.76SDUY817
<p>SDUY817 is a dual APN/NEP inhibitor with IC50 values of 0.29 μM for APN and 7.4 μM for NEP. It exhibits analgesic effects in a concentration- and time-dependent manner, making it a potential candidate for research in the field of neuropathic pain disorders.</p>Formule :C18H16IN3O3Couleur et forme :SolidMasse moléculaire :449.24CD13-IN-1
<p>CD13-IN-1 (Compound 5f) is a CD13 inhibitor with an IC50 value of 1.71 μM. It effectively suppresses the proliferation of various tumor cells, demonstrating antitumor activity.</p>Couleur et forme :Odour SolidAmastatin hydrochloride
CAS :<p>Amastatin HCl is an inhibitor of aminopeptidase. It also induces vasoconstriction.</p>Formule :C21H39ClN4O8Couleur et forme :White To Off-White PowderMasse moléculaire :511.01ecMetAP-IN-1
CAS :<p>ecMetAP-IN-1 可用作 QSAR 模型，以使用多元线性回归研究蛋氨酸氨基肽酶抑制剂作为抗癌剂。</p>Formule :C13H11N3Degré de pureté :99.34%Couleur et forme :SolidMasse moléculaire :209.25NGR peptide
CAS :<p>Cell-penetrating peptide</p>Formule :C20H36N10O8S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :608.69JNJ-40929837 succinate
CAS :<p>JNJ-40929837 succinate is a selective, orally active inhibitor of LTA 4 H (leukotriene A 4 hydrolase). This compound effectively inhibits aminopeptidase activity, leading to the accumulation of Pro-Gly-Pro in serum, and can be utilized in asthma research [1].</p>Formule :C22H24N4O2S·xC4H6O4Couleur et forme :SolidBDM_92499
<p>BDM_92499 is a nanomolar, selective IRAP inhibitor with an IC50 of 3.4 nM. It also inhibits ERAP1 and ERAP2, with IC50 values of 0.46 μM and 4.2 μM, respectively.</p>Couleur et forme :Odour SolidAclimostat
CAS :<p>Aclimostat (ZGN-1061) is a MetAP2 inhibitor with strong preclinical results, improving obesity-related metrics and gene expression.</p>Formule :C26H42N2O6Couleur et forme :SolidMasse moléculaire :478.63Relzomostat
CAS :<p>Relzomostat inhibits MetAP2, with research potential for obesity and type 2 diabetes.</p>Formule :C24H36F2N2O5Couleur et forme :SolidMasse moléculaire :470.558SDUY816
<p>SDUY816 is an orally active dual APN/NEP inhibitor, with IC50 values of 0.68 μM for APN and 6.9 μM for NEP. It exhibits analgesic properties and demonstrates good safety and pharmacokinetic profiles, having an oral bioavailability of 27% and a half-life of 4.02 hours in rats (oral, 10 mg/kg). SDUY816 is applicable for research in the field of neuropathic pain disorders.</p>Formule :C18H16IN3O3Couleur et forme :SolidMasse moléculaire :449.24ERAP1-IN-3
<p>ERAP1-IN-3 (compound 13) is a potent inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1), with a pIC50 value of 8.6. ERAP1-IN-3 shows potential for research in cancer immunotherapy and autoimmune disease studies.</p>Formule :C22H22N2O4SCouleur et forme :SolidMasse moléculaire :410.49DG013A formate
<p>DG013A (formate) is a tripeptide-mimicking inhibitor of hypophosphorous acid. It exhibits IC50 values of 33 nM for ERAP1 and 11 nM for ERAP2. This compound can be utilized in research related to autoimmune diseases and cancer.</p>Formule :C27H37N4O4PCH2O2Couleur et forme :SolidMasse moléculaire :530.99
