Caséine Kinase
Les caséine kinases sont une famille de kinases protéiques sérine/thréonine qui régulent divers processus cellulaires, y compris la réparation de l'ADN, les rythmes circadiens et la transduction du signal. Ces kinases sont impliquées dans la phosphorylation de nombreuses protéines et sont associées à des maladies telles que le cancer, les troubles neurodégénératifs et les syndromes métaboliques. Chez CymitQuimica, nous proposons une sélection d'inhibiteurs de la caséine kinase pour soutenir vos recherches sur la transduction du signal, la régulation du cycle cellulaire et le développement thérapeutique.
130 produits trouvés pour "Caséine Kinase"
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Emodin
CAS :<p>Emodin (Frangula emodin) is a selective 11β-HSD1 inhibitor,IC50 of 186 and 86 nM against 11β-HSD1 in humans and mice. High-Quality, Low-Cost!</p>Formule :C15H10O5Degré de pureté :98.37% - 99.53%Couleur et forme :Physical Description Orange Needles Or Powder (Ntp 1992)Masse moléculaire :270.24Ellagic acid
CAS :<p>Ellagic acid (Gallogen), a thickened tetracyclic natural product, is a potent CK2 inhibitor. Ellagic acid is an antioxidant. Cost-effective and quality-assured.</p>Formule :C14H6O8Degré de pureté :97.11% - 99.75%Couleur et forme :Cream Colored Needles From Pyridine 1992)Masse moléculaire :302.19Silmitasertib sodium salt
CAS :<p>Silmitasertib sodium salt (CX-4945 sodium salt) is a potent and orally bioavailable, highly selective inhibitor of CK2(IC50 of 1 nM, CK2α).</p>Formule :C19H11ClN3NaO2Degré de pureté :99.49% - 99.62%Couleur et forme :SolidMasse moléculaire :371.75A-3 hydrochloride
CAS :<p>A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.</p>Formule :C12H14Cl2N2O2SDegré de pureté :99.32%Couleur et forme :SolidMasse moléculaire :321.22NMS-P715
CAS :<p>NMS-P715 is a highly selective and ATP-competitive MPS1 inhibitor(IC50 of 182 nM).</p>Formule :C35H39F3N8O3Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :676.73CIGB-300
CAS :<p>CIGB-300 (P15-Tat) is an anti-casein kinase 2 (CK2) peptide that exhibits anticancer properties by disrupting the phosphorylation activity of protein kinase CK2. The compound induces apoptosis in various tumor cell lines, making it valuable for research in cancer therapy.</p>Formule :C127H215N53O30S3Couleur et forme :SolidMasse moléculaire :3060.6CSNK2-IN-2
<p>CSNK2-IN-2 (compound 2) is an orally active inhibitor of CSNK2. It is utilized in antiviral research.</p>Formule :C25H30FN9OCouleur et forme :SolidMasse moléculaire :491.56CK1-IN-4
<p>CK1-IN-4 (Compound 59) is an inhibitor of casein kinase CK1δ with an IC50 of 2.74 μM. It exhibits neuroprotective activity in SH-SY5Y cells treated with Ethacrynic acid.</p>Couleur et forme :Odour SolidWAY-297174
CAS :<p>WAY-297174 is a human protein kinase CK2 inhibitor with IC50 of > 33 μM.</p>Formule :C11H12N2O2S2Degré de pureté :99.53%Couleur et forme :SoildMasse moléculaire :268.36Ellagic acid (hydrate)
CAS :<p>Ellagic acid (hydrate) is a natural antioxidant and acts as a potent and ATP-competitive CK2 inhibitor (IC50:40 nM, Ki: 20 nM).</p>Formule :C14H8O9Degré de pureté :98%Couleur et forme :Green To Beige PowderMasse moléculaire :320.21AH078
<p>AH078 (compound 37) is a selective PROTAC degrader targeting CK1δ and CK1ε with low selectivity for CK1α. AH078 consists of a PROTAC linker (black part) Monomethyl octanoate, a target protein ligand (red part) CK1δ/CK1ε ligand-1, and an E3 ligase ligand (blue part) E3 Ligase Ligand 58. The E3 ligase ligand combined with the linker forms the conjugate E3 Ligase Ligand-linker Conjugate 163.</p>Formule :C51H60F2N10O5SCouleur et forme :SolidMasse moléculaire :963.15GSK-3β/CK-1δ-IN-1
<p>GSK-3β/CK-1δ-IN-1 (8d) is a dual inhibitor of GSK-3β and CK-1δ that can cross the blood-brain barrier, with IC50 values of 0.77 μM and 0.57 μM, respectively. GSK-3β/CK-1δ-IN-1 (8d) is applicable in neuroblastoma research.</p>Formule :C22H17F3N4OCouleur et forme :SolidMasse moléculaire :410.39Casein Kinase 2 Substrate Peptide
CAS :<p>CK2 Substrate Peptide, C-terminus linked to EDANS, used for CK2 activity assays.</p>Formule :C45H73N19O24Couleur et forme :SolidMasse moléculaire :1264.17CK2-IN-13
<p>CK2-IN-13 (compound 12c) is a potent inhibitor of CK2, with an IC50 value of 5.8 nM, playing a significant role in cancer research.</p>Formule :C19H13Br2NO3Couleur et forme :SolidMasse moléculaire :463.119Casein
CAS :<p>Casein is a milk protein with multiple roles involved in novel drug delivery systems.</p>Degré de pureté :95%Couleur et forme :SoildCasein kinase 1δ-IN-14
CAS :<p>Casein kinase 1δ-IN-14 (WAY-637081) can be used to study atherosclerosis-related cardiovascular disease.</p>Formule :C17H11ClN4O2Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :338.75CK1-IN-3
CAS :<p>WAY-296817 inhibits CK1, potential for circadian rhythm and inflammation research.</p>Formule :C17H16N2O3SDegré de pureté :99.18%Couleur et forme :SolidMasse moléculaire :328.39Casein kinase 1δ-IN-9
CAS :<p>Casein kinase 1δ-IN-9 is a Quinone reductase 2 inhibitor with IC50 of 0.6μM.</p>Formule :C15H12ClN3Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :269.73Casein Kinase Substrates 3
CAS :<p>Casein Kinase Substrates 3 is a substrate of casein kinase.</p>Formule :C85H139N27O35SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2131.24TBCA
CAS :<p>TBCA: selective CK2 inhibitor, IC50=110 nM, Ki=77 nM, favors CK2 over CK1, DYRK1A, and 27 other kinases.</p>Formule :C9H4Br4O2Degré de pureté :99.3%Couleur et forme :SolidMasse moléculaire :463.74Casein kinase 1δ-IN-7
CAS :<p>Casein kinase 1δ-IN-7 is a Casein kinase 1δ inhibitor for neurodegenerative diseases such as Alzheimer's disease.</p>Formule :C17H14N4O2SDegré de pureté :98.6%Couleur et forme :SolidMasse moléculaire :338.38Casein kinase 1δ-IN-8
CAS :<p>Casein kinase 1δ-IN-8 is an inhibitor of casein kinase 1δ and is used to treat neurodegenerative diseases such as Alzheimer's disease type.</p>Formule :C19H14FN5OSDegré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :379.41CK2-IN-14
<p>CK2-IN-14 (Compound 10b) is an inhibitor of cyclin-dependent kinase 2α with an IC50 of 36.7 nM. It effectively hinders the growth of cancer cell lines 786-O and U937, with GI50 values of 7.3 μM and 7.5 μM, respectively.</p>Formule :C19H20ClN5SCouleur et forme :SolidMasse moléculaire :385.91Casein kinase 1δ-IN-6
CAS :<p>CK1δ-IN-6: potent, selective CK-1δ inhibitor, IC50 23 nM, neuroprotective, anti-inflammatory, for neurodegenerative research.</p>Formule :C16H10ClF3N2OSDegré de pureté :99%Couleur et forme :SoildMasse moléculaire :370.78Casein kinase 1δ-IN-15
CAS :<p>Casein kinase 1δ-IN-15, an inhibitor for casein kinase 1 (CK1δ), exhibits an IC50 of 0.045 μM [1].</p>Formule :C19H17FN6OCouleur et forme :SolidMasse moléculaire :364.38Casein kinase 1δ-IN-3
CAS :<p>Casein kinase 1δ-IN-3 (Casein kinase 1δ-IN-3) (Compound 23a) is a casein kinase 1 delta (CK1d) inhibitor with a pIC50 of 6.5376 M.</p>Formule :C17H16N2O2SDegré de pureté :98.94%Couleur et forme :SoildMasse moléculaire :312.39QXG-6442
<p>QXG-6442 is a molecular glue degrader targeting CK1α, demonstrating a degradation potency with a DC50 of 5.7 nM and a Dmax of 90%. In the MOLM-14 cell line, QXG-6442 induces antiproliferative effects.</p>Formule :C21H17N5O4Couleur et forme :SolidMasse moléculaire :403.39MU1742
<p>MU1742 is a probe for CK1δ and CK1ε protein kinases [1] .</p>Formule :C22H22F2N6Couleur et forme :SolidMasse moléculaire :408.45CK1δ/CK1ε liagnd-1
<p>CK1δ/CK1ε ligand-1 is a ligand of CK1δ/CK1ε and can serve as a target protein ligand for the synthesis of the CK1 PROTAC degrader AH078.</p>Formule :C21H20F2N6Couleur et forme :SolidMasse moléculaire :394.42CZP-IN-1
<p>CZP-IN-1 (compound SH-1) is an inhibitor targeting the pathogen Trypanosoma cruzi protease (CZP) without affecting cathepsin L (IC50=28 nM). This compound is applicable in Chagas disease research.</p>Formule :C20H26N4O4SCouleur et forme :SolidMasse moléculaire :418.51FPFT-2216
CAS :<p>FPFT-2216 is a "molecular glue" compound with potential anti-tumor activity that degrades IKZF6, IKZF1, DE1D and can be used to study immune system diseases.</p>Formule :C12H12N4O3SDegré de pureté :99.35% - 99.62%Couleur et forme :SolidMasse moléculaire :292.31PF-5006739
CAS :<p>PF-5006739: potent, selective CK1δ/ε inhibitor (IC50: 3.9/17.0 nM); may treat psychiatric disorders, improves glucose tolerance, reduces opioid seeking.</p>Formule :C22H22FN7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :419.45MRT00033659
CAS :<p>MRT00033659 inhibits CK1 (IC50=0.9 μM), CHK1 (IC50=0.23 μM), activates p53, and destabilizes E2F-1; it's a pyrazolo-pyridine.</p>Formule :C15H14N4OCouleur et forme :SolidMasse moléculaire :266.3SGC-CK2-1
CAS :<p>SGC-CK2-1, a CK2 inhibitor, is a inducer of insulin production and secretion in pancreatic β-cells.</p>Formule :C20H21N7ODegré de pureté :99.41%Couleur et forme :SolidMasse moléculaire :375.43Longdaysin
CAS :<p>Longdaysin is an inhibitor of CK1α and CK1δ (IC50s: 5.6/8.8 μM). It also can inhibit ERK2 (IC50: 52 μM).</p>Formule :C16H16F3N5Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :335.33TA-01
CAS :<p>TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively.</p>Formule :C20H12F3N3Degré de pureté :99.55% - 99.94%Couleur et forme :SolidMasse moléculaire :351.32Epiblastin A
CAS :<p>Epiblastin A inhibits CK1, targets its isoenzymes, and converts EpiSCs to cESCs.</p>Formule :C12H10ClN7Degré de pureté :99.45%Couleur et forme :SolidMasse moléculaire :287.71IWP-2
CAS :<p>IWP-2 is a Wnt pathway inhibitor and an ATP-competitive CK1δ inhibitor. IWP-2 inhibits self-renewal of embryonic stem cells. Cost effective and quality assured.</p>Formule :C22H18N4O2S3Degré de pureté :96.1% - 99.49%Couleur et forme :SolidMasse moléculaire :466.6SR-3029
CAS :<p>SR-3029 is a potent and highly specific CK1δ/CK1ε inhibitor.</p>Formule :C23H19F3N8ODegré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :480.45TTP 22
CAS :<p>TTP 22: ATP-competitive CK2 inhibitor; IC50/Ki: 0.1 μM/40 nM; >250x selective over JNK3, ROCK1, MET.</p>Formule :C16H14N2O2S2Degré de pureté :97.08% - 97.78%Couleur et forme :SolidMasse moléculaire :330.42LY294002
CAS :<p>LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM).</p>Formule :C19H17NO3Degré de pureté :98% - 99.96%Couleur et forme :Pale Yellow SolidMasse moléculaire :307.34CKI-7 free base
CAS :<p>CKI-7 free base is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor.</p>Formule :C11H12ClN3O2SCouleur et forme :SolidMasse moléculaire :285.75IC261
CAS :<p>IC261 (SU-5607) is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50 of IC261 for CK1 was 16 μM and for Cdk5 is 4.5 mM.</p>Formule :C18H17NO4Degré de pureté :99.45% - 99.91%Couleur et forme :SolidMasse moléculaire :311.33LY-294002 hydrochloride
CAS :<p>LY-294002 HCl (NSC 697286) is a stable PI3K inhibitor (IC50: 0.5-0.97 µM) and prevents autophagosome formation.</p>Formule :C19H17NO3·HClDegré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :343.81LH846
CAS :<p>LH846 is a selective inhibitor of CK1δ (IC50 values are 290 nM, 1.3 uM and 2.5 uM for CK1δ, ε and α); exhibits no inhibitory activity at CK2.</p>Formule :C16H13ClN2OSDegré de pureté :90% - 98.26%Couleur et forme :SolidMasse moléculaire :316.81PF-4800567
CAS :<p>PF-4800567 is a selective inhibitor of casein kinase 1ε (CK1ε; IC50 = 32 nM) with greater than 20-fold selectivity over CK1δ.</p>Formule :C17H18ClN5O2Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :359.81Orobol
CAS :<p>Orobol (3’,4’,5,7-tetrahydroxy-isoflavon) is an inhibitor of tyrosine-specific protein kinase and phosphatidylinositol turnover.</p>Formule :C15H10O6Degré de pureté :98% - 98%Couleur et forme :SolidMasse moléculaire :286.24D4476
CAS :<p>D4476 (Casein Kinase I Inhibitor) is an effective, selective, and cell-permeant CK1 (casein kinase 1) inhibitor( IC50=300 nM in a cell-free assay).</p>Formule :C23H18N4O3Degré de pureté :99.7% - 99.96%Couleur et forme :SolidMasse moléculaire :398.41AS-252424
CAS :<p>AS-252424 is a potent and selective inhibitor of PI3Kγ with IC50 of 33 nM; >10 fold selectivity for PI3Kγ versus PI3Kα.</p>Formule :C14H8FNO4SDegré de pureté :99.06% - 99.09%Couleur et forme :SolidMasse moléculaire :305.28(E/Z)-GO289
CAS :<p>(E/Z)-GO289, which strongly lengthened circadian period, is a potent and selective inhibitor of CK2.</p>Formule :C17H15BrN4O2SDegré de pureté :98.1%Couleur et forme :SolidMasse moléculaire :419.3Umbralisib
CAS :<p>Umbralisib (TGR 1202) is a PI3Kδ inhibitor.</p>Formule :C31H24F3N5O3Degré de pureté :99.56% - 99.56%Couleur et forme :White SolidMasse moléculaire :571.55TBB
CAS :<p>TBB (NSC-231634)(NSC-231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2).</p>Formule :C6HBr4N3Degré de pureté :98.51% - 99.45%Couleur et forme :Off-White SolidMasse moléculaire :434.71CKI-7
CAS :<p>CKI-7 is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor.</p>Formule :C11H14Cl3N3O2SDegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :358.67Umbralisib hydrochloride
CAS :<p>Umbralisib hydrochloride: PI3Kδ inhibitor; IC50=22.2 nM, EC50=24.3 nM; active vs CK1ε, EC50=6.0 μM.</p>Formule :C31H25ClF3N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :608.01MLN8054
CAS :<p>MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.</p>Formule :C25H15ClF2N4O2Degré de pureté :98.07% - 98.26%Couleur et forme :SolidMasse moléculaire :476.86NCC007
CAS :<p>NCC007 is a novel CKIα and CKIδ dual inhibitors by structural modification of N9 and C2 position of longdaysin.</p>Formule :C22H28F3N7Degré de pureté :98.88%Couleur et forme :SolidMasse moléculaire :447.5CK2-IN-1
CAS :<p>CK2 inhibitor</p>Formule :C14H9NO3Degré de pureté :97.28%Couleur et forme :SolidMasse moléculaire :239.23CK1-IN-1
CAS :<p>CK1-IN-1, a CK1 inhibitor with IC50: 15nM CK1δ, 16nM CK1ε, 73nM p38σ; patent WO2015119579A1.</p>Formule :C24H15F2N3Degré de pureté :98.79%Couleur et forme :SolidMasse moléculaire :383.39TAK-715
CAS :<p>TAK-715 is a p38 MAPK inhibitor for p38α.</p>Formule :C24H21N3OSDegré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :399.51DMAT
CAS :<p>DMAT (Casein kinase II Inhibitor) is a potent and specific inhibitor of CK2(IC50 value of 130 nM).</p>Formule :C9H7Br4N3Degré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :476.79Silmitasertib
CAS :<p>Silmitasertib (CX-4945) is a potent, orally bioavailable inhibitor of casein kinase 2 (CK2; Ki: 0.38 nM).</p>Formule :C19H12ClN3O2Degré de pureté :98% - 99.90%Couleur et forme :SolidMasse moléculaire :349.77PF-670462
CAS :<p>PF-670462 is a potent (IC50 = 7.7 ± 2.2 nM) and selective (>30-fold with respect to 42 additional kinases) inhibitor of CK1ε in isolated enzyme preparations.</p>Formule :C19H22Cl2FN5Degré de pureté :99.42% - 99.72%Couleur et forme :SolidMasse moléculaire :410.32XL413
CAS :<p>XL-413 is an oral CDC7 kinase inhibitor, potentially blocking DNA replication, mitosis, and cancer cell growth.</p>Formule :C14H12ClN3O2Degré de pureté :98.40% - >99.99%Couleur et forme :SolidMasse moléculaire :289.72SSTC3
CAS :<p>SSTC3 is a casein kinase 1α (CK1α) activator with potential antitumor activity that inhibits WNT signaling.</p>Formule :C23H17F3N4O3S2Degré de pureté :98.65% - 99.94%Couleur et forme :SolidMasse moléculaire :518.53AMG-548
CAS :<p>AMG-548, oral p38α inhibitor (Ki=0.5 nM), >1000x selectivity over p38γ/δ, blocks TNFα (IC50=3 nM), also inhibits Wnt/Casein kinase 1δ/ε.</p>Formule :C29H27N5ODegré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :461.56SR-1277
CAS :<p>SR-1277 is a potent, highly selective and ATP-competitive CK1δ/ε inhibitor, regulating Wee1 activity at the G2/M cell-cycle interface, and antiproliferative.</p>Formule :C21H19N9O3SCouleur et forme :SolidMasse moléculaire :477.5CK2/PIM1-IN-1
CAS :<p>CK2/PIM1-IN-1 inhibits CK2 & PIM1 (IC50s: 3.787 & 4.327 μM), aimed for cancer research.</p>Formule :C15H9NO4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :331.374,5,6,7-Tetrabromobenzimidazole
CAS :<p>4,5,6,7-Tetrabromobenzimidazole is a selective and ATP-competitive inhibitor of protein kinase CK2 [1].</p>Formule :C7H2Br4N2Couleur et forme :SolidMasse moléculaire :433.72CK2-IN-9
CAS :<p>CK2-IN-9, a potent and selective CK2 kinase inhibitor, exhibits an inhibitory concentration (IC50) of 3 nM against its target enzyme and hampers Wnt reporter</p>Formule :C23H29N9OCouleur et forme :SolidMasse moléculaire :447.54Quinalizarin
CAS :<p>Quinalizarin, the most selective CK2 inhibitor, is superior to CX-4945 which is the first-in-class CK2 inhibitor.</p>Formule :C14H8O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :272.21Tyrphostin AG 1112
CAS :<p>Tyrphostin AG 1112 is a Bcr-Abl kinase blocker. It can activate the terminal differentiation of K562 cells and the purging of Ph+ cells.</p>Formule :C15H10N6Couleur et forme :SolidMasse moléculaire :274.28PF 4800567 hydrochloride
CAS :<p>casein kinase 1ε inhibitor</p>Formule :C17H19Cl2N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :396.27IQA
CAS :<p>IQA is a casein kinase 2 (CK2) inhibitor.</p>Formule :C17H12N2O3Couleur et forme :SolidMasse moléculaire :292.29(R)-DRF053 dihydrochloride
CAS :<p>cdk/CK1 inhibitor,potent and ATP-competitive</p>Formule :C23H29Cl2N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :490.43TMCB
CAS :<p>CK2 and ERK8 inhibitor</p>Formule :C11H9Br4N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :534.82CK2-IN-6
CAS :<p>CK2-IN-6: Potent CK2 inhibitor for cancer, inflammation, pain, and immune research.</p>Formule :C19H16ClN7O2Couleur et forme :SolidMasse moléculaire :409.83SRPIN-803
CAS :<p>SRPIN-803 is a selective dual SRPK1 and CK2 inhibitor.</p>Formule :C14H9F3N4O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :370.31Umbralisib sulfate
CAS :<p>Umbralisib sulfate, an oral dual PI3Kδ/CK1ε inhibitor (EC50: 22.2 nM/6.0 μM), targets CLL T cells for blood cancer research.</p>Formule :C31H26F3N5O7SCouleur et forme :SolidMasse moléculaire :669.63Umbralisib tosylate
CAS :<p>Umbralisib tosylate, an oral PI3Kδ/CK1ε inhibitor (EC50: 22.2 nM/6.0 μM), shows promise for CLL research.</p>Formule :C38H32F3N5O6SCouleur et forme :SolidMasse moléculaire :743.75BTX161
CAS :<p>BTX161: potent CKIα degrader, surpasses Lenalidomide in AML, triggers DDR + p53, stabilizes MDM2.</p>Formule :C15H16N2O3Couleur et forme :SolidMasse moléculaire :272.3HDAC/CK2-IN-1
CAS :<p>HDAC/CK2-IN-1 (compound 38) acts as an inhibitor of HDAC1 (IC 50 = 1.46 μM), HDAC6 (IC 50 = 0.66 μM), and CK2 (IC 50 = 3.67 μM). It demonstrates promising antiproliferative effects on various cell lines, including Jurkat, MCF-7, HCT-116, and HL-60.</p>Formule :C15H18Br4N4O2Couleur et forme :SolidMasse moléculaire :605.95CK2-IN-4
CAS :<p>CK2-IN-4 is a protein kinase (CK2) inhibitor with an IC50 value of 8.6 µM.</p>Formule :C18H11N3O4SDegré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :365.36CK2α-IN-1
CAS :<p>CK2α-IN-1 is a selective non-ATP-competitive CK2α inhibitor with an IC50 of 7.0 µM and a Ki of 1.6 µM.CK2α-IN-1 exhibits potential anticancer activity and can</p>Formule :C16H11N3O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :341.34CK1-IN-2
CAS :<p>CK1-IN-2 (compound Nr.4) is a potent CK1 inhibitor p38a, and is used in DUX4 overexpression-associated diseases, such as muscular dystrophy.</p>Formule :C17H12FN3O2Degré de pureté :99.31%Couleur et forme :SolidMasse moléculaire :309.29PI-828
CAS :<p>PI-828 (LY 294002), a PI3K inhibitor, researches PI3K function and aids stem cell differentiation into mesoderm.</p>Formule :C19H18N2O3Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :322.36XL413 xHCl
CAS :<p>BMS-863233 HCl is an ATP-competitive Cdc7 inhibitor (IC50: 3.4 nM) that is potent and selective.BMS-863233 HCl inhibited CK2 and PIM1 with IC50 values of 215</p>Formule :C14H12ClN3O2·xHClDegré de pureté :99.37% - 99.67%Couleur et forme :SolidMasse moléculaire :326.18BioE-1115
CAS :<p>BioE-1115 is a selective and potent inhibitor of serine-threonine protein kinase (PASK, IC50 = 4 nM). BioE-1115 is a potent inhibitor of CK2α (IC50 = 10 μM).</p>Formule :C19H18FN3O2Degré de pureté :97.54%Couleur et forme :SolidMasse moléculaire :339.36Casein kinase 1δ-IN-1
CAS :<p>Casein kinase 1δ-IN-1 (WAY-643895) is an inhibitor of casein kinase 1δ (CK1δ), which inhibits CK1δ.</p>Formule :C11H7N3OSDegré de pureté :99.46%Couleur et forme :SolidMasse moléculaire :229.26Ac-VDVAD-CHO
CAS :<p>Ac-VDVAD-CHO is an inhibitor of caspase-2 and caspase-3 (IC50: 46 nM for caspase-2 and 15 nM for caspase-3) [1].</p>Formule :C23H37N5O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :543.57ON 108600
CAS :<p>ON 108600 is a chemical inhibitor targeting CK2 (Casein Kinase 2), TNIK, and DYRK1, demonstrating IC50 values of 0.016 μM and 0.007 μM for DYRK1A and DYRK1B, 0.</p>Formule :C22H14Cl2N2O6S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :537.39Casein kinase 1δ-IN-5
CAS :<p>Casein kinase 1δ-IN-5 is a potent and selective CK-1δ inhibitor, exhibiting an IC50 of 47 nM, and demonstrates neuroprotective and anti-inflammatory effects in</p>Formule :C16H11F3N2OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :336.33Casein kinase 1δ-IN-10
CAS :<p>Casein kinase 1δ-IN-10 is an inhibitor of casein kinase 1δ (CK1δ).</p>Formule :C21H17N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :359.38TID43
CAS :<p>TID43, a CK2 inhibitor, exhibits potent inhibition with an IC50 value of 0.3 μM. It is applicable in anti-angiogenic research [1].</p>Formule :C10H3I4NO4Couleur et forme :SolidMasse moléculaire :708.755XL413 hydrochloride
CAS :<p>XL413 hydrochloride (BMS-863233 Hydrochloride) is a potent, selective and ATP competitive inhibitor of Cdc7. XL413 hydrochloride also inhibits CK2 and PIM1.</p>Formule :C14H13Cl2N3O2Degré de pureté :98.81% - 99.8%Couleur et forme :SolidMasse moléculaire :326.18Casein kinase 1δ-IN-4
CAS :<p>"Casein kinase 1δ-IN-4 (compound 567) is a potent inhibitor of casein kinase 1δ with potential application in Alzheimer's disease research [1]."</p>Formule :C16H12N6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :320.37Casein Kinase II Inhibitor IV
CAS :<p>Casein kinase II inhibitor IV is an effective small molecule inducer, which can be used to induce epidermal keratinocyte differentiation.</p>Formule :C24H23N5O3Degré de pureté :99.65% - 99.75%Couleur et forme :SolidMasse moléculaire :429.47Casein kinase 1δ-IN-13
CAS :Casein kinase1δ-IN-13 (compound 401) is an inhibitor of Casein kinase1δ. It is utilized in the research of neurodegenerative diseases.Formule :C15H13N3O2SCouleur et forme :SolidMasse moléculaire :299.35Casein kinase 1δ-IN-28
CAS :<p>Casein kinase1δ-IN-28 (Compound 4) is an inhibitor of CK1ε, with an IC50 of 0.0146 μM. The human liver microsome metabolism rate for Casein kinase1δ-IN-28 is 52%.</p>Formule :C23H23FN6Couleur et forme :SolidMasse moléculaire :402.467CK1δ-IN-6
CAS :<p>CK1δ-IN-6 (Compound 303) is an inhibitor of Casein kinase 1δ, with potential applications in Alzheimer's disease research.</p>Formule :C23H17N3O4Couleur et forme :SolidMasse moléculaire :399.399WAY-606344
CAS :<p>WAY-606344 (Compound 97) is an inhibitor of Casein kinase 1δ and shows potential for Alzheimer's disease research.</p>Formule :C14H8ClN3O2Couleur et forme :SolidMasse moléculaire :285.685CK1δ-IN-5
CAS :<p>CK1δ-IN-5 (Compound 24) is an inhibitor of casein kinase 1δ (CK1δ) and can be used in the study of neurodegenerative diseases.</p>Formule :C22H21N5Couleur et forme :SolidMasse moléculaire :355.436Casein kinase 1δ-IN-27
CAS :<p>Casein kinase1δ-IN-27 (Compound 8) is an inhibitor of casein kinase 1 (CK1), effectively inhibiting CK1α, CK1δ, CK1ε, and p38α with IC50 values of 22, 16.5, 9.41, and 14.8 nM, respectively. It also suppresses DUX4 expression, with an IC50 of 10 nM.</p>Formule :C21H19FN6Couleur et forme :SolidMasse moléculaire :374.414CK1δ-IN-7
CAS :<p>CK1δ-IN-7 (Compound 488) is an inhibitor of casein kinase 1δ (CK1δ).</p>Formule :C23H23N5OCouleur et forme :SolidMasse moléculaire :385.462p38α inhibitor 8
CAS :<p>p38α inhibitor8 (Compound 1) demonstrates inhibitory activity against p38αMAPK and CK1δ, with IC50 values of 0.21 µM and 0.202 µM, respectively.</p>Formule :C17H13FN6Couleur et forme :SolidMasse moléculaire :320.324dCK1α-2
<p>dCK1α-2 is an orally effective CK1α molecular glue (Molecular Glue) degrader that targets p53 pathway-related targets. It demonstrates antitumor efficacy in mouse models by enhancing the expression of p53-related genes.</p>Formule :C24H24ClN5O4Couleur et forme :SolidMasse moléculaire :481.93CK1δ-IN-9
CAS :<p>CK1δ-IN-9 (Compound 8) is an inhibitor of casein kinase 1 (CK1), specifically targeting CK1δ with an IC50 of 1.4 nM. The compound also inhibits p38α and p38β with IC50 values of 0.25 μM and 0.78 μM, respectively. CK1δ-IN-9 exhibits favorable pharmacokinetic properties, including high oral bioavailability (70%) and moderate clearance.</p>Formule :C16H12FN5Couleur et forme :SolidMasse moléculaire :293.298Casein kinase 1δ-IN-31
CAS :<p>Casein kinase1δ-IN-31 (Compound 16) is an inhibitor of casein kinase (CK), specifically targeting CK1α, CK1δ, and p38α, with IC50 values of 196 nM, 17 nM, and 18 nM, respectively. Additionally, Casein kinase1δ-IN-31 inhibits Double Homeobox 4 (DUX4) with an IC50 of 1200 nM.</p>Formule :C17H13FN4Couleur et forme :SolidMasse moléculaire :292.31MGD-28
CAS :<p>MGD-28 is a Cullin-CRBN-dependent IKZF family protein degrader for IKZF1 (Ikaros), IKZF2 (Helios), IKZF3 (Aiolos) ,and CK1α, antiproliferative.</p>Formule :C33H34FN7O3Degré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :595.67CK1δ-IN-10
CAS :<p>CK1δ-IN-10 (Compound 85) is an inhibitor of casein kinase 1 (CK1), specifically targeting CK1δ (CSNKID), with an IC50 value of 0.255 μM.</p>Formule :C17H11F4N5Couleur et forme :SolidMasse moléculaire :361.296Casein kinase 1δ-IN-16
CAS :<p>Casein kinase1δ-IN-16 (compound 506) is an inhibitor of casein kinase 1δ (CK1δ). This compound is applicable in research related to neurodegenerative diseases.</p>Formule :C17H12N4S2Couleur et forme :SolidMasse moléculaire :336.434CK1δ-IN-8
CAS :<p>CK1δ-IN-8 (Compound 429) is a CK1δ inhibitor suitable for Alzheimer's disease research.</p>Formule :C14H9N3O2S2Couleur et forme :SolidMasse moléculaire :315.37Casein kinase 1δ-IN-30
CAS :<p>Casein kinase1δ-IN-30 (Compound 581) is an inhibitor of casein kinase 1δ (CK1δ). It can be utilized in research related to neurodegenerative diseases.</p>Formule :C18H15BrN6O2SCouleur et forme :SolidMasse moléculaire :459.32p38α MAPK/CK1δ inhibitor-1
CAS :<p>p38αMAPK/CK1δ inhibitor-1 (Compound 3) exhibits inhibitory activity against p38αMAPK and CK1δ, with IC50 values of 0.185 µM and 0.089 µM, respectively.</p>Formule :C24H17FN6O2Couleur et forme :SolidMasse moléculaire :440.429Casein kinase 1δ-IN-18
CAS :<p>Casein kinase1δ-IN-18 (compound 660) is an inhibitor of casein kinase 1δ (CK1δ), which can be utilized for research in neurodegenerative diseases.</p>Formule :C16H12ClN3O2S2Couleur et forme :SolidMasse moléculaire :377.868(R,R)-BMS-986397
CAS :<p>(R,R)-BMS-986397 is a CK1α degrader with a DC50 ranging from 0.1 to 0.5 pM. This compound is applicable in leukemia research.</p>Formule :C21H16ClF3N4O4Couleur et forme :SolidMasse moléculaire :480.82DEG-35
CAS :<p>DEG-35 is a CRBN-dependent bifunctional degrader targeting IKZF2 and CK1α, with DC50 values of 1.4 nM and 4.4 nM for CK1α and IKZF2, respectively. It activates the p53 apoptotic pathway and is applicable for research related to acute myeloid leukemia (AML).</p>Formule :C25H21N3O5Couleur et forme :SolidMasse moléculaire :443.45AMG-548 dihydrochloride
<p>AMG-548 dihydrochloride, an oral p38α inhibitor (Ki: 0.5 nM), selectively targets p38β, γ, δ, inhibits TNFα (IC50: 3 nM), and suppresses Wnt signaling.</p>Formule :C29H29Cl2N5OCouleur et forme :SolidMasse moléculaire :534.48Casein kinase 1δ-IN-26
CAS :<p>Casein kinase1δ-IN-26 (compound 505) is a potent inhibitor of casein kinase 1δ. This compound is applicable in research related to neurodegenerative disorders such as Alzheimer’s disease.</p>Formule :C16H13N3O4SCouleur et forme :SolidMasse moléculaire :343.357AMG-548 hydrochloride
<p>AMG-548 hydrochloride: orally active, p38α inhibitor (Ki=0.5 nM), 1000x less for p38γ/δ, also blocks TNFα (IC50=3 nM) & inhibits casein kinase 1 δ/ε.</p>Formule :C29H28ClN5OCouleur et forme :SolidMasse moléculaire :498.02CK2 inhibitor 3
<p>CK2 inhibitor 3: potent CK2 blocker, IC50 of 280 nM, suppresses tumor cell growth, highly selective among 320 kinases.</p>Formule :C13H9BrN4O3SCouleur et forme :SolidMasse moléculaire :381.2Casein Kinase II Inhibitor IV Hydrochloride
CAS :<p>Casein Kinase II Inhibitor IV HCl promotes keratinocyte differentiation, potential for skin disorder therapy.</p>Formule :C24H24ClN5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :465.93CK2-IN-3
<p>CK2-IN-3: potent, selective CK2 inhibitor; Kd=12 nM, IC50: 1.51 μM (CK2α), 7.64 μM (CK2α'). For cancer research.</p>Formule :C22H26N4O7Couleur et forme :SolidMasse moléculaire :458.46Casein kinase 1δ-IN-19
CAS :<p>Casein kinase1δ-IN-19 (compound 492) is a potent inhibitor of casein kinase 1δ. It is utilized in research related to neurodegenerative disorders, such as Alzheimer's disease.</p>Formule :C21H19N5O3Couleur et forme :SolidMasse moléculaire :389.407Casein kinase 1δ-IN-23
CAS :<p>Casein kinase1δ-IN-23 (compound 423) is an effective inhibitor of casein kinase1δ. It is applicable in research related to neurodegenerative diseases such as Alzheimer's disease.</p>Formule :C19H15N3O3SCouleur et forme :SolidMasse moléculaire :365.406Casein kinase 1δ-IN-25
CAS :<p>Casein kinase1δ-IN-25 (compound 487) is a potent inhibitor of casein kinase1δ. It is applicable in research on neurodegenerative diseases such as Alzheimer's disease.</p>Formule :C20H14FN3O4S2Couleur et forme :SolidMasse moléculaire :443.471CK1δ-IN-3
CAS :<p>CK1δ-IN-3 (compound 376) is a CK1δ (casein kinase 1δ) inhibitor that can be used to study neurodegenerative diseases such as Alzheimer's disease.</p>Formule :C24H19N3O2SDegré de pureté :99.27%Couleur et forme :SolidMasse moléculaire :413.49TMX-4113
<p>TMX-4113 has potential to be used in cancer that is a phosphodiesterase 6D(PDE6D) and casein kinase 1α(CK1α) degrader [1].</p>Formule :C12H12N4O2S2Couleur et forme :SolidMasse moléculaire :308.38Casein kinase 1δ-IN-17
CAS :<p>Casein kinase1δ-IN-17 (compound 753) is an inhibitor of casein kinase 1δ (CK1δ). It is applicable in research related to neurodegenerative diseases.</p>Formule :C14H14N4SCouleur et forme :SolidMasse moléculaire :270.353TMX-4116
CAS :<p>TMX-4116 is a CK1α degrader targeting multiple cell lines with DC50s below 200 nM, used in multiple myeloma research and protein degradation strategy studies.</p>Formule :C17H19N5O4SCouleur et forme :SolidMasse moléculaire :389.43CK2 inhibitor 2
CAS :<p>CK2 Inhibitor 2, characterized as a potent, selective, and orally active inhibitor of CK2, demonstrates an impressive IC50 value of 0.66 nM.</p>Formule :C21H17ClN4O2Degré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :392.84
