Facteur Xa
Le facteur Xa est une enzyme cruciale dans la cascade de coagulation qui convertit la prothrombine en thrombine, entraînant la formation de caillots sanguins. L'inhibition du facteur Xa est une stratégie thérapeutique largement utilisée pour prévenir et traiter les troubles thromboemboliques, tels que la thrombose veineuse profonde, l'embolie pulmonaire et l'AVC. Chez CymitQuimica, nous proposons des inhibiteurs du facteur Xa pour soutenir vos recherches en hématologie, santé cardiovasculaire et thérapie anticoagulante.
80 produits trouvés pour "Facteur Xa"
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Rivaroxaban
CAS :<p>Rivaroxaban (BAY 59-7939) is an oral, direct factor Xa inhibitor with anticoagulant properties, interfering with thrombin formation.</p>Formule :C19H18ClN3O5SDegré de pureté :99.93% - >99.99%Couleur et forme :SolidMasse moléculaire :435.88Gabexate mesylate
CAS :<p>Gabexate mesylate (FOY) inhibits thrombin, plasmin, kallikrein; used for pancreatitis, DIC, hemodialysis anticoagulant.</p>Formule :C17H27N3O7SDegré de pureté :99.2% - 99.64%Couleur et forme :White CrystalMasse moléculaire :417.48Letaxaban
CAS :<p>Letaxaban (TAK-442) is a small molecule Xa factor inhibitor that can be used to study polar coronary syndromes and thrombotic blockages.</p>Formule :C22H26ClN3O5SDegré de pureté :99.13% - 99.87%Couleur et forme :SolidMasse moléculaire :479.985-R-Rivaroxaban
CAS :<p>5-R-Rivaroxaban is the (R)-enantiomer of Rivaroxaban, a potent FXa inhibitor with IC50 0.7 nM and Ki 0.4 nM.</p>Formule :C19H18ClN3O5SDegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :435.88Osocimab
CAS :<p>Osocimab (BAY 1213790) is a strong FXIa inhibitor, Ki 2.4 nM, EC50 0.2 nM, and reduces thrombosis in research.</p>Degré de pureté :> 95% - > 95%Couleur et forme :LiquidMasse moléculaire :144.46 kDa2-Methoxyphenothiazine
CAS :<p>2-Methoxy Phenothiazine is light yellow or light gray solid.</p>Formule :C13H11NOSDegré de pureté :99.28%Couleur et forme :Orange Yellow Crystal PowderMasse moléculaire :229.3Ciraparantag acetate
CAS :<p>Ciraparantag acetate reverses anticoagulation, binding heparins and DOACs noncovalently.</p>Formule :C24H52N12O4Degré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :572.75Garadacimab
CAS :<p>Garadacimab (CSL312) is a human IgG4 antibody against FXIIa, used to research hereditary angioedema.</p>Degré de pureté :SDS-PAGE:95% SEC-HPLC:99.99%Couleur et forme :LiquidMasse moléculaire :146.5 kDaCanine Factor Xa
<p>CanineFactor Xa is derived from purified Canine Factor X through activation by Russell's Viper Venom, after which the venom is removed.</p>Couleur et forme :Odour SolidD-Pro-Phe-Arg-Chloromethylketone
CAS :<p>D-Pro-Phe-Arg-Chloromethylketone, an inhibitor of coagulation factor XII and plasma kallikrein, is significant in the regulation of thrombosis and inflammation</p>Formule :C21H31ClN6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :450.96FXIa-IN-15
CAS :<p>FXIa-IN-15 (Compound (S)-10h) is an inhibitor of factor XIa (FXIa) and plasma kallikrein (PKa) with IC50 values of 0.38 nM and 59.2 nM, respectively. It exhibits anticoagulant properties by prolonging the 50% activated partial thromboplastin time (aPTT) with an EC1.5X of 0.55 μM.</p>Formule :C32H23ClF3N7O4Couleur et forme :SolidMasse moléculaire :662.02CH3OCO-D-CHA-Gly-Arg-pNA acetate
CAS :<p>CH3OCO-D-CHA-Gly-Arg-pNA acetate serves as a chromogenic substrate for Factor Xa, as documented in sources [1] [2].</p>Formule :C27H42N8O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :622.67O-Desmethyl apixaban sulfate sodium
<p>O-Desmethyl apixaban sulfate sodium inhibits factor X (FXa) with a Ki of 58 μM,and is a major circulating metabolite of Apixaban in humans.</p>Formule :C24H22N5NaO7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :547.52Edoxaban Isomer
CAS :<p>Edoxaban Isomer is an impurity of Edoxaban, which is a novel inhibitor of factor Xa.</p>Formule :C24H30ClN7O4SCouleur et forme :SolidMasse moléculaire :548.06FXIIa-IN-1 HCl
CAS :<p>FXIIa-IN-1 HCl is a selective inhibitor of Factor XIIa,and can be used to study thrombosis and inflammation induced by artificial surfaces.</p>Formule :C21H17ClN2O6Degré de pureté :99.61%Couleur et forme :SoildMasse moléculaire :428.82Boc-Ile-Glu-Gly-Arg-AMC
CAS :<p>Boc-IEGR-AMC: fluorogenic substrate for factor Xa and Halocynthia roretzi acrosin.</p>Formule :C34H50N8O10Degré de pureté :98%Couleur et forme :White PowderMasse moléculaire :730.81Edoxaban impurity 6
CAS :<p>Edoxaban impurity 6 is a byproduct of the anticoagulant Edoxaban, a potent oral factor Xa inhibitor with Kis of 0.561 nM. Used to prevent stroke.</p>Formule :C16H22ClN5O3Couleur et forme :SolidMasse moléculaire :367.83Lofacimig
<p>Lofacimig is a bispecific antibody of VH-VH-G1(h-CH2-CH3) dimer type that targets FXI/PTA.</p>Couleur et forme :Odour LiquidRabbit Factor Xa
<p>RabbitFactor Xa is produced from purified Rabbit Factor X through activation by Russells' Viper Venom, followed by the removal of the venom.</p>Couleur et forme :Odour SolidMethoxycarbonyl-D-Nle-Gly-Arg-pNA
CAS :<p>Methoxycarbonyl-D-Nle-Gly-Arg-pNA is a synthetic trypsin substrate utilized for coagulation factors IXa (FIXa) and Xa (FXa), as evidenced by studies [1] [2] [3</p>Formule :C22H34N8O7Couleur et forme :SolidMasse moléculaire :522.55cMCoFx1
CAS :<p>cMCoFx1 is an effective and selective FXIIa cyclic peptide inhibitor. It exhibits high binding affinity for FXIIa (KD: 900 pM) and potent inhibitory activity (Ki: 370 pM). cMCoFx1 effectively suppresses the intrinsic coagulation pathway, demonstrates high stability in serum, and shows no cytotoxicity.</p>Formule :C146H232N52O44S6Couleur et forme :SolidMasse moléculaire :3612.12Naroparcil
CAS :<p>Naroparcil, an oral thioglycoside, has antithrombotic properties and alters thrombin complex formation.</p>Formule :C19H17NO4S2Degré de pureté :98.71% - 99.88%Couleur et forme :SolidMasse moléculaire :387.47FXIIa-IN-4
<p>FXIIa-IN-4 (compound 22) is a potent and selective human FXIIa inhibitor, exhibiting IC50 values of 0.032 μM for FXIIa, 0.30 μM for thrombin, and >50 μM for FXIa. It is utilized in anticoagulant research.</p>Formule :C11H9FN4O3Masse moléculaire :264.06587Concizumab
CAS :<p>Concizumab is an anti-TFPI monoclonal antibody (IgG4 type) that selectively binds to the Kunitz protease inhibitor (KPI) 2 domain of TFPI, thereby blocking the</p>Degré de pureté :> 95%Couleur et forme :LiquidMasse moléculaire :145.76 kDaAsundexian
CAS :<p>Asundexian (BAY-2433334) is a potent and orally active inhibitor of the coagulation factor FXIa that directly and reversibly binds to the active site of FXIa,</p>Formule :C26H21ClF4N6O4Degré de pureté :99.89% - 99.90%Couleur et forme :SolidMasse moléculaire :592.93Rat Factor Xa
<p>RatFactor Xa is derived from the activation of purified Rat Factor X using Russells' Viper Venom. Following activation, Russells' Viper Venom is removed.</p>Couleur et forme :Odour SolidPorcine Factor Xa
CAS :<p>PorcineFactor Xa is obtained by activating purified Porcine Factor X using Russells' Viper Venom, after which the venom is removed.</p>Couleur et forme :SolidApixaban 13C,d3
CAS :<p>Apixaban 13C,d3 is a deuterium labeling of Apixaban for isotopic tracing. Apixaban 13C,d3 is a selective inhibitor of coagulation factor Xa</p>Formule :C25H25N5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :463.51Betrixaban-d6
CAS :<p>Betrixaban D6 is a deuterium-labeled Betrixaban. Betrixaban is a selective and orally efficacious FXa inhibitor.</p>Formule :C23H22ClN5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :457.95Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
CAS :<p>Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl) compound inhibits coagulation factor Xa, useful for thrombotic conditions study.</p>Formule :C27H28N4O5Degré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :488.54Enoxaparin sodium
CAS :<p>Enoxaparin, a low-weight heparin approved by FDA for STEMI, enhances antithrombin and prevents clotting by inhibiting factors XIa, IXa, Xa, IIa.</p>Formule :C42H59N3Na4O35S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1322Apixaban
CAS :<p>Apixaban (BMS-562247-01) is an orally active inhibitor of coagulation factor Xa with anticoagulant activity.</p>Formule :C25H25N5O4Degré de pureté :99.73% - 99.93%Couleur et forme :SolidMasse moléculaire :459.5Edoxaban Tosylate Monohydrate
CAS :<p>Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.</p>Formule :C31H40ClN7O8S2Degré de pureté :99.86% - 99.91%Couleur et forme :SolidMasse moléculaire :738.27BISMUTH SUBGALLATE
CAS :<p>Bismuth subgallate (Dermatol Puder) is an astringent and antiseptic and is applied to skin diseases such as eczema.</p>Formule :C7H5BiO6Degré de pureté :98.7%Couleur et forme :White To Yellow CrystalsMasse moléculaire :394.09Benzamidine hydrochloride
CAS :<p>Benzamidine hydrochloride (Benzamidine HCl) is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin.</p>Formule :C7H9ClN2Degré de pureté :99.25% - 99.97%Couleur et forme :White To Off-White PowderMasse moléculaire :156.614-Chlorophenylurea
CAS :<p>4-Chlorophenylurea (NSC-12971) is a novel orally bioavailable inhibitor of factor Xa.</p>Formule :C7H7ClN2ODegré de pureté :98.87%Couleur et forme :White Granular / PrillMasse moléculaire :170.6Darexaban
CAS :<p>Darexaban (YM-150) selectively inhibits Factor Xa, reducing clotting and risk of heart/stroke events.</p>Formule :C27H30N4O4Degré de pureté :98.33%Couleur et forme :SolidMasse moléculaire :474.55Fondaparinux sodium
CAS :<p>Fondaparinux sodium (SR-90107A) is an antithrombin-dependent factor Xa inhibitor with antithrombotic activity.</p>Formule :C31H43N3Na10O49S8Degré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :1728.08Edoxaban hydrochloride
CAS :<p>Edoxaban (DU-176b) HCl: Oral, selective Factor Xa inhibitor, Ki 0.561 nM; prevents thromboembolic disease.</p>Formule :C24H31Cl2N7O4SCouleur et forme :SolidMasse moléculaire :584.52Betrixaban hydrochloride(330942-05-7(free base))
<p>Betrixaban hydrochloride(330942-05-7(free base)) (PRT054021 hydrochloride) is a potent, selective, and orally efficacious factor Xa (fXa) inhibitor (IC50: 1.5</p>Formule :C23H23Cl2N5O3Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :488.36Heparin sodium salt
CAS :<p>Heparin sodium, a sulfated glycosaminoglycan, acts as an anticoagulant and inhibits exosome-cell interactions.</p>Formule :C26H42N2NaO37S5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1157.89Abelacimab
CAS :<p>NI-0801 (Anti-CXCL10 / IP-1) is a CHO-expressed humanized monoclonal antibody targeting CXCL10/IP-10 for the study of vitiligo and biliary cirrhosis.</p>Degré de pureté :94.9% (SDS-PAGE); 99.1% (SEC-HPLC) - 94.9% (SDS-PAGE); 99.1% (SEC-HPLC)Couleur et forme :LiquidEdoxaban-d6
CAS :<p>Edoxaban-d6 is a deuterated compound of Edoxaban. Edoxaban has a CAS number of 480449-70-5. Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.</p>Formule :C24H24D6ClN7O4SCouleur et forme :SolidMasse moléculaire :554.09Betrixaban maleate
CAS :<p>"Betrixaban, a non-vitamin K anticoagulant by Portola, inhibits factor Xa with low hERG affinity, preventing VTE in at-risk adults."</p>Formule :C27H26ClN5O7Degré de pureté :99.46% - 99.86%Couleur et forme :SolidMasse moléculaire :567.98Rivaroxaban-d4
CAS :<p>Rivaroxaban-d4 is a deuterated marker of Rivaroxaban for isotopic tracing.BAY 59-7939 is a potent and selective direct inhibitor of coagulation factor Xa (FXa.</p>Formule :C19H18ClN3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :439.91Betrixaban
CAS :<p>Betrixaban is a non-VKORC1 anticoagulant targeting factor Xa, with low hERG affinity, used to prevent VTE in adults with mobility issues.</p>Formule :C23H22ClN5O3Degré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :451.91Milvexian
CAS :<p>Milvexian (BMS-986177) is an oral antithrombotic, reversibly inhibiting human/rabbit FXIa with K i of 0.11/0.38 nM.</p>Formule :C28H23Cl2F2N9O2Couleur et forme :SolidMasse moléculaire :626.45YM-75466
CAS :<p>YM-75466 is a factor Xa inhibitor reducing TAT in plasma dose-dependently without prolonging coagulation.</p>Formule :C28H35N5O8S2Couleur et forme :SolidMasse moléculaire :633.74Pegnivacogin
CAS :<p>Pegnivacogin is a coagulation factor IXa RNA aptamer inhibitor.</p>Formule :C20H40N3O11PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :529.52BMS 740808
CAS :<p>BMS-740808 is a highly effective and selective factor X inhibitor.</p>Formule :C31H27F3N6O3Couleur et forme :SolidMasse moléculaire :588.58Ciraparantag TFA
CAS :<p>Ciraparantag TFA reverses anticoagulants by inhibiting thrombin and factor Xa.</p>Formule :C26H50F6N12O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :740.74Ciraparantag
CAS :<p>Ciraparantag inhibits thrombin, factor Xa, and reverses various anticoagulants.</p>Formule :C22H48N12O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :512.7Darexaban glucuronide
CAS :<p>Darexaban glucuronide is the major component in plasma after oral administration of darexaban to humans. Darexaban (YM150) is a direct inhibitor of factor Xa.</p>Formule :C33H38N4O10Couleur et forme :SolidMasse moléculaire :650.68Tanogitran
CAS :<p>Tanogitran, a coagulation factor Xa inhibitor, is used potentially for the treatment of septic shock.</p>Formule :C25H31N7O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :477.56DPC-423
CAS :<p>DPC-423 is a factor Xa inhibitor potentially for the treatment of thrombosis.</p>Formule :C25H21ClF4N4O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :568.97Razaxaban hydrochloride
CAS :<p>Razaxaban hydrochloride is a highly potent, selective and orally active inhibitor of factor Xa(Ki of 0.19 nM),has strongly antithrombotic activity.</p>Formule :C24H21ClF4N8O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :564.92Otamixaban
CAS :<p>Otamixaban (FXV673) is a selective and highly effective Xa inhibitor that inhibits the generation of thrombin and can be used to study acute coronary syndrome.</p>Formule :C25H26N4O4Degré de pureté :98.08%Couleur et forme :SolidMasse moléculaire :446.5Eribaxaban
CAS :<p>Eribaxaban (PD348292) is an orally available factor Xa inhibitor for the prevention and treatment of venous thromboembolism.</p>Formule :C24H22ClFN4O4Degré de pureté :98.99% - 99.13%Couleur et forme :SolidMasse moléculaire :484.91Fidexaban
CAS :<p>Fidexaban (CI1031) is a novel, potent, selective and orally active factor Xa inhibitor that has demonstrated antithrombotic activity in a variety of assays</p>Formule :C25H24F2N6O5Degré de pureté :98.64% - 99.43%Couleur et forme :SolidMasse moléculaire :526.49LY 517717
CAS :<p>LY 517717 is an orally active inhibitor of coagulation factor Xa with antithrombotic activity for the study of venous thromboembolism (VTE).</p>Formule :C27H33N5O2Degré de pureté :99.77% - 99.88%Couleur et forme :SolidMasse moléculaire :459.58Edoxaban
CAS :<p>Edoxaban: potent, selective FXa inhibitor; Ki 0.561 nM. Used as an oral anticoagulant for stroke prevention, also inhibits thrombin and FIXa.</p>Formule :C24H30ClN7O4SDegré de pureté :97.67% - 99.71%Couleur et forme :SolidMasse moléculaire :548.06Zifaxaban
CAS :<p>Zifaxaban (TY-602) is an oral selective factor Xa inhibitor with an IC50 of 11.1 nM, highly specific over other serine proteases, used in thrombosis studies.</p>Formule :C20H16ClN3O4SDegré de pureté :97.46% - 99.82%Couleur et forme :SolidMasse moléculaire :429.88BMS-262084
CAS :<p>BMS-262084 is a potent selective β-lactam trypsin inhibitor with therapeutic potential in the treatment of asthma.</p>Formule :C18H31N7O5Couleur et forme :SolidMasse moléculaire :425.48FXIa-IN-1
CAS :<p>FXIa-IN-1 is a potent β-lactam covalent heparin-derived factor XIa (fXIa) inhibitor.</p>Formule :C20H19F3N4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :452.38Frunexian
CAS :<p>Frunexian (EP-7041) is a selective and potent inhibitor of coagulation factor XI/activated factor XI, specifically targeting XIa.</p>Formule :C19H26N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :374.43AS1468240
CAS :<p>AS1468240 is a factor Xa inhibitor. It has significant oral anticoagulant activity.</p>Formule :C25H25Cl2N5O3Couleur et forme :SolidMasse moléculaire :514.4BI-11634
CAS :<p>BI-11634 is a factor Xa inhibitor.</p>Formule :C22H23ClN4NaO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :465.89BMS-962212
CAS :<p>BMS-962212: reversible, selective FXIa blocker, well-tolerated, quick PD effect, rapid clearance, alters clotting time/activity.</p>Formule :C32H28ClFN8O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :659.07FXIa-IN-7
CAS :<p>FXIa-IN-7 is an orally available, selective and potent inhibitor of factor XIa for the study of thrombophilia.</p>Formule :C28H28N2O4Degré de pureté :98.55%Couleur et forme :SolidMasse moléculaire :456.53BMS-654457
CAS :<p>BMS-654457 is a small-molecule, reversible inhibitor of factor XIa (FXIa; Kis: 0.2 and 0.42 nM for human and rabbit FXIa).</p>Formule :C36H37N5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :603.71FXa-IN-1
CAS :<p>FXa-IN-1, an FXa blocker: IC50=3 nM, Ki=0.7 nM, orally available, long half-life, for thrombosis research.</p>Formule :C24H18F5N5OCouleur et forme :SolidMasse moléculaire :487.42Dechloro Rivaroxaban
CAS :<p>Dechloro Rivaroxaban is a Factor Xa inhibitor that inhibits free FXa and plasminogen and fibrin-associated FXa activity in humans.</p>Formule :C19H19N3O5SDegré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :401.44DX-9065A HCl hydrate
CAS :<p>DX-9065a: Competitive fXa/prothrombinase inhibitor; blocks proinflammatory events; Ki ~10-20 nM.</p>Formule :C26H39ClN4O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :571.06BAY 3389934
CAS :<p>BAY 3389934 is a dual inhibitor of factor IIa (factor IIa) and factor Xa (factor Xa), providing anticoagulant and organ-protective effects. It alleviates coagulopathy and organ dysfunction in baboon models of Staphylococcus aureus sepsis.</p>Formule :C26H30ClN5O7S2Couleur et forme :SolidMasse moléculaire :624.129RWJ-445167
CAS :<p>RWJ-445167 is a thrombin and factor Xa dual inhibitor(Ki of 4.0 nM and 230 nM, respectively), with potent antithrombotic activity.</p>Formule :C18H24N6O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :436.49FXIa-6f
CAS :<p>FXIa-6f is a high affinity, orally bioavailable macrocyclic FXIa inhibitor with antithrombotic activity in preclinical species</p>Formule :C31H29ClF2N4O4Couleur et forme :SolidMasse moléculaire :595.04FXIa-IN-6
CAS :<p>FXIa-IN-6: Potent, selective FXIa inhibitor (Ki=0.3 nM); strong PK with high oral bioavailability, low clearance preclinically.</p>Formule :C31H29ClF2N4O4Couleur et forme :SolidMasse moléculaire :595.04FXIa-IN-9
CAS :<p>FXIa-IN-9, a potent FXIa inhibitor (K i : human 0.17 nM, rabbit 0.5 nM), forms hydrogen bonds and has anticoagulant properties.</p>Formule :C23H18Cl2F3N9O2Couleur et forme :SolidMasse moléculaire :580.35FXIa-IN-8
<p>FXIa-IN-8: potent FXIa blocker (IC50: 14.2 nM), anti-thrombotic, low bleeding/toxicity risk.</p>Couleur et forme :Solid5-Chlorothiophene-2-carboxylic acid
CAS :<p>5-Chlorothiophene-2-carboxylic acid [catalog number: T66447, CAS number: 24065-33-6] is a valuable organic compound for life sciences research.</p>Formule :C5H3ClO2SCouleur et forme :SolidMasse moléculaire :162.59
