Facteur Xa
Le facteur Xa est une enzyme cruciale dans la cascade de coagulation qui convertit la prothrombine en thrombine, entraînant la formation de caillots sanguins. L'inhibition du facteur Xa est une stratégie thérapeutique largement utilisée pour prévenir et traiter les troubles thromboemboliques, tels que la thrombose veineuse profonde, l'embolie pulmonaire et l'AVC. Chez CymitQuimica, nous proposons des inhibiteurs du facteur Xa pour soutenir vos recherches en hématologie, santé cardiovasculaire et thérapie anticoagulante.
87 produits trouvés pour "Facteur Xa"
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Letaxaban
CAS :Letaxaban (TAK-442) is a small molecule Xa factor inhibitor that can be used to study polar coronary syndromes and thrombotic blockages.Formule :C22H26ClN3O5SDegré de pureté :99.13% - 99.87%Couleur et forme :SolidMasse moléculaire :479.98Ciraparantag acetate
CAS :Ciraparantag acetate reverses anticoagulation, binding heparins and DOACs noncovalently.Formule :C24H52N12O4Degré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :572.75Ref: TM-T10820L1
2mg46,00€5mg66,00€10mg97,00€1mL*10mM (DMSO)107,00€25mg188,00€50mg311,00€100mg512,00€Osocimab
CAS :Osocimab (BAY 1213790) is a strong FXIa inhibitor, Ki 2.4 nM, EC50 0.2 nM, and reduces thrombosis in research.
Degré de pureté :> 95% - > 95%Couleur et forme :LiquidMasse moléculaire :144.46 kDa5-R-Rivaroxaban
CAS :5-R-Rivaroxaban is the (R)-enantiomer of Rivaroxaban, a potent FXa inhibitor with IC50 0.7 nM and Ki 0.4 nM.
Formule :C19H18ClN3O5SDegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :435.88Gabexate mesylate
CAS :Gabexate mesylate (FOY) inhibits thrombin, plasmin, kallikrein; used for pancreatitis, DIC, hemodialysis anticoagulant.Formule :C17H27N3O7SDegré de pureté :99.2% - 99.64%Couleur et forme :White CrystalMasse moléculaire :417.482-Methoxyphenothiazine
CAS :2-Methoxy Phenothiazine is light yellow or light gray solid.Formule :C13H11NOSDegré de pureté :99.28%Couleur et forme :Orange Yellow Crystal PowderMasse moléculaire :229.3Garadacimab
CAS :Garadacimab (CSL312) is a human IgG4 antibody against FXIIa, used to research hereditary angioedema.Degré de pureté :SDS-PAGE:95% SEC-HPLC:99.99%Couleur et forme :LiquidMasse moléculaire :146.5 kDaRivaroxaban
CAS :Rivaroxaban (BAY 59-7939) is an oral, direct factor Xa inhibitor with anticoagulant properties, interfering with thrombin formation.Formule :C19H18ClN3O5SDegré de pureté :99.93% - >99.99%Couleur et forme :SolidMasse moléculaire :435.88Ref: TM-T1184
2mg35,00€5mg52,00€1mL*10mM (DMSO)58,00€10mg70,00€25mg95,00€50mg118,00€100mg178,00€200mg264,00€Canine Factor Xa
CanineFactor Xa is derived from purified Canine Factor X through activation by Russell's Viper Venom, after which the venom is removed.Couleur et forme :Odour SolidRabbit Factor Xa
RabbitFactor Xa is produced from purified Rabbit Factor X through activation by Russells' Viper Venom, followed by the removal of the venom.Couleur et forme :Odour SolidCH3OCO-D-CHA-Gly-Arg-pNA acetate
CAS :CH3OCO-D-CHA-Gly-Arg-pNA acetate serves as a chromogenic substrate for Factor Xa, as documented in sources [1] [2].Formule :C27H42N8O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :622.67O-Desmethyl apixaban sulfate sodium
O-Desmethyl apixaban sulfate sodium inhibits factor X (FXa) with a Ki of 58 μM,and is a major circulating metabolite of Apixaban in humans.Formule :C24H22N5NaO7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :547.52FXIIa-IN-1 HCl
CAS :FXIIa-IN-1 HCl is a selective inhibitor of Factor XIIa,and can be used to study thrombosis and inflammation induced by artificial surfaces.Formule :C21H17ClN2O6Degré de pureté :99.61%Couleur et forme :SoildMasse moléculaire :428.82Porcine Factor Xa
CAS :PorcineFactor Xa is obtained by activating purified Porcine Factor X using Russells' Viper Venom, after which the venom is removed.Couleur et forme :SolidD-Pro-Phe-Arg-Chloromethylketone
CAS :D-Pro-Phe-Arg-Chloromethylketone, an inhibitor of coagulation factor XII and plasma kallikrein, is significant in the regulation of thrombosis and inflammationFormule :C21H31ClN6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :450.96FXIa-IN-15
CAS :FXIa-IN-15 (Compound (S)-10h) is an inhibitor of factor XIa (FXIa) and plasma kallikrein (PKa) with IC50 values of 0.38 nM and 59.2 nM, respectively. It exhibits anticoagulant properties by prolonging the 50% activated partial thromboplastin time (aPTT) with an EC1.5X of 0.55 μM.Formule :C32H23ClF3N7O4Couleur et forme :SolidMasse moléculaire :662.02cMCoFx1
CAS :cMCoFx1 is an effective and selective FXIIa cyclic peptide inhibitor. It exhibits high binding affinity for FXIIa (KD: 900 pM) and potent inhibitory activity (Ki: 370 pM). cMCoFx1 effectively suppresses the intrinsic coagulation pathway, demonstrates high stability in serum, and shows no cytotoxicity.Formule :C146H232N52O44S6Couleur et forme :SolidMasse moléculaire :3612.12Methoxycarbonyl-D-Nle-Gly-Arg-pNA
CAS :Methoxycarbonyl-D-Nle-Gly-Arg-pNA is a synthetic trypsin substrate utilized for coagulation factors IXa (FIXa) and Xa (FXa), as evidenced by studies [1] [2] [3Formule :C22H34N8O7Couleur et forme :SolidMasse moléculaire :522.55Asundexian
CAS :Asundexian (BAY-2433334) is a potent and orally active inhibitor of the coagulation factor FXIa that directly and reversibly binds to the active site of FXIa,Formule :C26H21ClF4N6O4Degré de pureté :99.89% - 99.90%Couleur et forme :SolidMasse moléculaire :592.93Rat Factor Xa
RatFactor Xa is derived from the activation of purified Rat Factor X using Russells' Viper Venom. Following activation, Russells' Viper Venom is removed.Couleur et forme :Odour SolidBoc-Ile-Glu-Gly-Arg-AMC
CAS :Boc-IEGR-AMC: fluorogenic substrate for factor Xa and Halocynthia roretzi acrosin.Formule :C34H50N8O10Degré de pureté :98%Couleur et forme :White PowderMasse moléculaire :730.81Lofacimig
Lofacimig is a bispecific antibody of VH-VH-G1(h-CH2-CH3) dimer type that targets FXI/PTA.Couleur et forme :Odour LiquidD-Leu-Pro-Arg-Rh110-D-Pro
D-Leu-Pro-Arg-Rh110-D-Pro serves as a substrate for Factor XaI (FXIa) and exhibits binding affinity. This compound is composed of Rhodamine 110 linked to a peptide chain via a cleavable bond. Upon cleavage, the intensity of the fluorophore is enhanced. D-Leu-Pro-Arg-Rh110-D-Pro can be utilized to detect FXIa activity.Formule :C42H51N9O7Masse moléculaire :793.39115Razaxaban
CAS :Razaxaban (also known as BMS-561389 or DPC 906) is an oral inhibitor of Factor Xa, initially developed for the treatment of thrombosis.Formule :C24H20F4N8O2Couleur et forme :SolidMasse moléculaire :528.46FXIIa-IN-3
FXIIa-IN-3 (Compound 8) is an effective and selective inhibitor of Factor XIIa (FXIIa), with an IC50 of 0.045 μM. It demonstrates significant selectivity over related serine proteases, including FXIa, FXa, and FIXa. FXIIa-IN-3 is suitable for research in thromboembolic diseases.Formule :C14H16N4O6Masse moléculaire :336.10698D-Leu-Pro-Arg-Rh110-D-Pro acetate
D-Leu-Pro-Arg-Rh110-D-Pro acetate is a substrate for Factor XaI (FXIa) with binding affinity. This compound is formed by linking Rhodamine 110 to a peptide chain via a cleavable bond. The cleavage of this bond enhances the intensity of the fluorophore. D-Leu-Pro-Arg-Rh110-D-Pro acetate can be used to detect FXIa activity.Formule :C42H51N9O7·xC2H4O2Naroparcil
CAS :Naroparcil, an oral thioglycoside, has antithrombotic properties and alters thrombin complex formation.Formule :C19H17NO4S2Degré de pureté :99.88% - 99.99%Couleur et forme :SolidMasse moléculaire :387.47Chromozym PK
CAS :Chromozym PK is a chromogenic substrate for factor XII assay.Formule :C33H38N8O6Couleur et forme :SolidMasse moléculaire :642.70Concizumab
CAS :Concizumab is an anti-TFPI monoclonal antibody (IgG4 type) that selectively binds to the Kunitz protease inhibitor (KPI) 2 domain of TFPI, thereby blocking theDegré de pureté :> 95%Couleur et forme :LiquidMasse moléculaire :145.76 kDaEdoxaban impurity 6
CAS :Edoxaban impurity 6 is a byproduct of the anticoagulant Edoxaban, a potent oral factor Xa inhibitor with Kis of 0.561 nM. Used to prevent stroke.
Formule :C16H22ClN5O3Couleur et forme :SolidMasse moléculaire :367.83Edoxaban Isomer
CAS :Edoxaban Isomer is an impurity of Edoxaban, which is a novel inhibitor of factor Xa.Formule :C24H30ClN7O4SCouleur et forme :SolidMasse moléculaire :548.06FXIIa-IN-4
FXIIa-IN-4 (compound 22) is a potent and selective human FXIIa inhibitor, exhibiting IC50 values of 0.032 μM for FXIIa, 0.30 μM for thrombin, and >50 μM for FXIa. It is utilized in anticoagulant research.Formule :C11H9FN4O3Masse moléculaire :264.06587Betrixaban-d6
CAS :Betrixaban D6 is a deuterium-labeled Betrixaban. Betrixaban is a selective and orally efficacious FXa inhibitor.Formule :C23H22ClN5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :457.95Apixaban 13C,d3
CAS :Apixaban 13C,d3 is a deuterium labeling of Apixaban for isotopic tracing. Apixaban 13C,d3 is a selective inhibitor of coagulation factor XaFormule :C25H25N5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :463.51Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
CAS :Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl) compound inhibits coagulation factor Xa, useful for thrombotic conditions study.
Formule :C27H28N4O5Degré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :488.54Edoxaban hydrochloride
CAS :Edoxaban (DU-176b) HCl: Oral, selective Factor Xa inhibitor, Ki 0.561 nM; prevents thromboembolic disease.Formule :C24H31Cl2N7O4SCouleur et forme :SolidMasse moléculaire :584.52BISMUTH SUBGALLATE
CAS :Bismuth subgallate (Dermatol Puder) is an astringent and antiseptic and is applied to skin diseases such as eczema.Formule :C7H5BiO6Degré de pureté :98.7%Couleur et forme :White To Yellow CrystalsMasse moléculaire :394.09Fondaparinux sodium
CAS :Fondaparinux sodium (SR-90107A) is an antithrombin-dependent factor Xa inhibitor with antithrombotic activity.Formule :C31H43N3Na10O49S8Degré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :1728.08Apixaban
CAS :Apixaban (BMS-562247-01) is an orally active inhibitor of coagulation factor Xa with anticoagulant activity.Formule :C25H25N5O4Degré de pureté :99.73% - 99.93%Couleur et forme :SolidMasse moléculaire :459.50Edoxaban Tosylate Monohydrate
CAS :Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.Formule :C31H40ClN7O8S2Degré de pureté :99.86% - 99.91%Couleur et forme :SolidMasse moléculaire :738.27Enoxaparin sodium
CAS :Enoxaparin, a low-weight heparin approved by FDA for STEMI, enhances antithrombin and prevents clotting by inhibiting factors XIa, IXa, Xa, IIa.Formule :C42H59N3Na4O35S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1322Betrixaban hydrochloride(330942-05-7(free base))
Betrixaban hydrochloride(330942-05-7(free base)) (PRT054021 hydrochloride) is a potent, selective, and orally efficacious factor Xa (fXa) inhibitor (IC50: 1.5Formule :C23H23Cl2N5O3Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :488.36Ref: TM-T4690
1mg46,00€2mg57,00€5mg92,00€1mL*10mM (DMSO)101,00€10mg145,00€25mg319,00€50mg492,00€100mg710,00€Benzamidine hydrochloride
CAS :Benzamidine hydrochloride (Benzamidine HCl) is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin.Formule :C7H9ClN2Degré de pureté :99.25% - 99.97%Couleur et forme :White To Off-White PowderMasse moléculaire :156.614-Chlorophenylurea
CAS :4-Chlorophenylurea (NSC-12971) is a novel orally bioavailable inhibitor of factor Xa.Formule :C7H7ClN2ODegré de pureté :98.87%Couleur et forme :White Granular / PrillMasse moléculaire :170.6Darexaban
CAS :Darexaban (YM-150) selectively inhibits Factor Xa, reducing clotting and risk of heart/stroke events.Formule :C27H30N4O4Degré de pureté :98.33%Couleur et forme :SolidMasse moléculaire :474.55Ref: TM-T31206
1mg46,00€5mg90,00€1mL*10mM (DMSO)96,00€10mg137,00€25mg222,00€50mg334,00€100mg485,00€200mg690,00€Abelacimab
CAS :NI-0801 (Anti-CXCL10 / IP-1) is a CHO-expressed humanized monoclonal antibody targeting CXCL10/IP-10 for the study of vitiligo and biliary cirrhosis.Degré de pureté :94.9% (SDS-PAGE); 99.1% (SEC-HPLC) - 94.9% (SDS-PAGE); 99.1% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :144.32 kDaEdoxaban-d6
CAS :Edoxaban-d6 is a deuterated compound of Edoxaban. Edoxaban has a CAS number of 480449-70-5. Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.Formule :C24H24D6ClN7O4SCouleur et forme :SolidMasse moléculaire :554.09Betrixaban maleate
CAS :"Betrixaban, a non-vitamin K anticoagulant by Portola, inhibits factor Xa with low hERG affinity, preventing VTE in at-risk adults."Formule :C27H26ClN5O7Degré de pureté :99.46% - 99.86%Couleur et forme :SolidMasse moléculaire :567.98Fitusiran
CAS :Fitusiran (ALN-AT3SC) is a siRNA that targets AT mRNA to reduce AT levels and boost thrombin, aiding hemophilia study.Couleur et forme :SolidRivaroxaban-d4
CAS :Rivaroxaban-d4 is a deuterated marker of Rivaroxaban for isotopic tracing.BAY 59-7939 is a potent and selective direct inhibitor of coagulation factor Xa (FXa.Formule :C19H18ClN3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :439.91
