
Anhydrase carbonique
L'anhydrase carbonique est une enzyme qui catalyse la conversion réversible du dioxyde de carbone et de l'eau en bicarbonate et protons. Cette enzyme joue un rôle crucial dans le maintien de l'équilibre acido-basique, la respiration et le transport du dioxyde de carbone dans le sang. Les inhibiteurs de l'anhydrase carbonique sont utilisés dans le traitement du glaucome, de l'épilepsie et du mal des montagnes, ainsi que dans la recherche sur l'homéostasie acido-basique et les échanges gazeux. Chez CymitQuimica, nous offrons une gamme d'inhibiteurs de l'anhydrase carbonique et de réactifs de haute qualité pour soutenir vos recherches en enzymologie, physiologie respiratoire et développement thérapeutique.
177 produits trouvés pour "Anhydrase carbonique"
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Benzthiazide
CAS :<p>Benzthiazide treats edema and hypertension by promoting diuresis and inhibiting kidney Na+/Cl- reuptake, but may reduce potassium and raise uric acid.</p>Formule :C15H14ClN3O4S3Degré de pureté :99.34% - 99.79%Couleur et forme :Crystals From Acetone SolidMasse moléculaire :431.94Methazolamide
CAS :<p>Methazolamide (CL 8490) is a carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.</p>Formule :C5H8N4O3S2Degré de pureté :99.31% - 99.77%Couleur et forme :Crystals From Water SolidMasse moléculaire :236.27Tioxolone
CAS :<p>Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor.</p>Formule :C7H4O3SDegré de pureté :97.79%Couleur et forme :Light Yellow To Beige PowderMasse moléculaire :168.17Zonisamide
CAS :<p>Zonisamide (AD 810), a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures.</p>Formule :C8H8N2O3SDegré de pureté :99.05% - 99.9%Couleur et forme :Off-White PowderMasse moléculaire :212.23Topiramate
CAS :<p>Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures.</p>Formule :C12H21NO8SDegré de pureté :99.79% - 99.92%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :339.36Methocarbamol
CAS :<p>Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established.</p>Formule :C11H15NO5Degré de pureté :99.96%Couleur et forme :Crystals From Benzene SolidMasse moléculaire :241.24pNNP
CAS :<p>pNNP is a substrate for PP2C assays and inhibits β-carbonic anhydrase, α-carbonate dehydrogenase, and H. pylori.</p>Formule :C6H6NO6PDegré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :219.09Brinzolamide
CAS :<p>Brinzolamide (AL-4862) is a Carbonic Anhydrase Inhibitor. The mechanism of action of brinzolamide is as a Carbonic Anhydrase Inhibitor.</p>Formule :C12H21N3O5S3Degré de pureté :99.84% - >99.99%Couleur et forme :Crystalline SolidMasse moléculaire :383.51Actarit
CAS :<p>Actarit (4-acetylaminophenylacetic acid) is an anti-inflammatory drug.</p>Formule :C10H11NO3Degré de pureté :99.64% - 99.74%Couleur et forme :White Or Off-White Crystal Or Crystalline SolidMasse moléculaire :193.2Acipimox
CAS :<p>Acipimox (K-9321), a niacin derivative, treats hyperlipidemia in type 2 diabetics.</p>Formule :C6H6N2O3Degré de pureté :98.98%Couleur et forme :Low Yellow Liquid Or CrystallineMasse moléculaire :154.12CA Ⅱ-IN-1
<p>CAⅡ-IN-1 (compound 2i) is an inhibitor of the CA Ⅱ isozyme, exhibiting an IC50 of 0.44 µM. This compound is utilized in metabolic research.</p>Formule :C18H19NO6SCouleur et forme :SolidMasse moléculaire :377.41Carbonic anhydrase inhibitor 30
<p>Carbonic anhydrase inhibitor30 (compound 17) is an inhibitor of carbonic anhydrase with Ki values of 2.13 μM for hCA I and 0.161 μM for hCA II[1].</p>Formule :C23H22FN3O5SCouleur et forme :SolidMasse moléculaire :471.12642CA IX/VEGFR-2-IN-3
<p>CAIX/VEGFR-2-IN-3 (Compound 6i) is an inhibitor of Carbonic Anhydrase IX and VEGFR-2, with IC50 values of 41 and 48 nM, respectively. It exhibits anticancer activity by inhibiting the growth of MCF-7 breast cancer cells (IC50 of 22.33 μM) and mouse fibroblast cell line 3T3, where cell viability is reduced to below 40% at a concentration of 100 μM. This compound is applicable for research in the field of cancer treatment.</p>Formule :C19H16ClN3O5S2Couleur et forme :SolidMasse moléculaire :465.93hCA/VEGFR-2-IN-3
<p>hCA/VEGFR-2-IN-3 (compound 8j) is an indolinonylbenzenesulfonamide with potential as a dual inhibitor of cancer-associated hCA IX/XII and VEGFR-2.</p>Formule :C24H28N6O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :528.58Phenylsulfamide
CAS :<p>Phenylsulfamide (Compound 10), acting as an inhibitor of human carbonic anhydrase-II (hCA-II), exhibits a dissociation constant (Kd) of 45.50 μM and an</p>Formule :C6H8N2O2SCouleur et forme :SolidMasse moléculaire :172.2hCAIX-IN-19
<p>hCAIX-IN-19 is a sulfonamide inhibitor with an inhibition constant (KI) of 6.2 nM for hCAIX, exhibiting significant selectivity towards hCAIX over hCAI (hCA I/</p>Couleur et forme :Odour SolidCAIX/CAXII-IN-3
<p>CAIX/CAXII-IN-3 (compound 11) serves as an inhibitor for CAIX/CAXII, exhibiting an IC50 value of less than 65 nM. Additionally, this compound effectively inhibits the proliferation of human melanoma cells.</p>Couleur et forme :Odour SolidCAIX/CAXII-IN-4
<p>CAIX/CAXII-IN-4 (Compound 7h) is an inhibitor of carbonic anhydrase (CA) that binds to CAIX, CA XII, and CAII with Ki values of 1.324 μM, 0.435 μM, and 3.035 μM, respectively. This compound exhibits broad-spectrum anti-tumor activity and inhibits the proliferation of central nervous system tumor cells U251, with a GI50 of 0.361 μM.</p>Formule :C23H21N5O3SCouleur et forme :SolidMasse moléculaire :447.51hCAII/IX-IN-1
<p>hCAII/IX-IN-1 (compound 4o) is a potent inhibitor of hCAII and hCAIX, with Ki values of 7.4 nM and 7.0 nM, respectively. It plays a significant role in cancer research.</p>Formule :C23H22N4O7S2Couleur et forme :SolidMasse moléculaire :530.573CA inhibitor 2
<p>Compound 4H is a potent carbonic anhydrase inhibitor with an IC50 value of 0.033 μM [1].</p>Formule :C7H9N7O3S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :335.392-Methoxy-4-propylphenol
CAS :<p>2-Methoxy-4-propylphenol is an inhibitor of human carbonic anhydrase isoenzymes 1/2/9/12 and has antifungal activity.</p>Formule :C10H14O2Couleur et forme :SolidMasse moléculaire :166.22hCA/VEGFR-2-IN-2
<p>Compound 8g (hCA/VEGFR-2-IN-2) is an indolinonylbenzenesulfonamide identified as a potential dual inhibitor targeting cancer-associated isozymes hCA IX/XII and</p>Formule :C23H26N6O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :498.55hCAII/XII-IN-1
<p>hCAII/XII-IN-1 (compound 4l) is a potent inhibitor of hCAXII and hCAII, with Ki values of 8.4 nM and 9.4 nM, respectively. It plays a significant role in cancer research.</p>Formule :C22H20N4O6S2Couleur et forme :SolidMasse moléculaire :500.547α-Pyrone
CAS :<p>Alpha-Pyrone exhibits inhibitory activity against tyrosinase, carbonic anhydrase 1, and carbonic anhydrase 9</p>Formule :C5H4O2Couleur et forme :SolidMasse moléculaire :96.08Carbonic anhydrase inhibitor 15
<p>Carbonic Anhydrase Inhibitor 15 (Compound 8), with an inhibitory constant (K_i) of 8.5 nM for hCA II, exhibits analgesic effects [1].</p>Formule :C27H33N5O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :523.71α-Glycosidase-IN-2
<p>α-Glycosidase-IN-2 (compound 8b) is an inhibitor of α-glycosidase, displaying Ki values of 74.16 nM and 6.09 nM for aldose reductase and α-glycosidase, respectively. This compound is utilized in research related to diabetes.</p>Formule :C25H22N6OS2Couleur et forme :SolidMasse moléculaire :486.61hCAI/II/IV-IN-28
CAS :<p>hCAI/II/IV-IN-28(WAY-638358) is a potent carbonic anhydrase inhibitor with potential anticonvulsant activity.</p>Formule :C14H15N3O3SDegré de pureté :96.48%Couleur et forme :SolidMasse moléculaire :305.35hCAXII-IN-7
<p>hCAXII-IN-7 (compound 6e) functions as an inhibitor of human carbonic anhydrase XII (hCA XII) and possesses blood-brain barrier (BBB) permeability.</p>Formule :C26H25N5O6S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :567.64hCAII-IN-7
<p>hCAII-IN-7 (R-13) inhibits human CA I, II, IV, IX with K i of 60.7, 320.7, 2298, 35.2 nM respectively.</p>Formule :C20H25N3O4SCouleur et forme :SolidMasse moléculaire :403.5hCAIX/VII-IN-1
<p>hCAIX/VII-IN-1 is a selective inhibitor of human carbonic anhydrase isoforms VII and IX.</p>Formule :C16H13BFN3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :325.1CAIX Inhibitor S4
CAS :<p>CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively.</p>Formule :C15H17N3O4SDegré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :335.38hCA/VEGFR-2-IN-1
<p>hCA/VEGFR-2-IN-1 (compound 13a) is a potent dual inhibitor targeting both Carbonic Anhydrase (CA) IX/XII and Vascular Endothelial Growth Factor Receptor 2 (</p>Formule :C21H17FN6O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :452.465,6-Dihydro-2H-pyran-2-one
CAS :<p>5,6-Dihydro-2H-pyran-2-one is a carbonic anhydrase 1/9 inhibitor that inhibits KB cell viability.</p>Formule :C5H6O2Couleur et forme :SolidMasse moléculaire :98.1hCAII-IN-6
<p>"hCAII-IN-6 (S-13) inhibits hCA II (4.4 nM) and isoforms I, IV, IX (9.2, 480.2, 14.7 nM). For glaucoma research."</p>Formule :C20H25N3O4SCouleur et forme :SolidMasse moléculaire :403.5hCAIX/XII-IN-7
<p>Compound 3e (hCAIX/XII-IN-7) is a potent inhibitor of human carbonic anhydrase (hCA) isozymes IX and XII, displaying inhibitory constants (Kis) of 503.7 nM for</p>Formule :C17H14N6O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :382.4hCA/VEGFR-2-IN-4
<p>hCA/VEGFR-2-IN-4 (compound 15b), an indolinylbenzenesulfonamide, serves as a potential dual inhibitor targeting cancer-related human carbonic anhydrases hCA IX/</p>Formule :C22H23FN6O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :502.52Pyrocatechol
CAS :<p>Pyrocatechol, often known as catechol or benzene-1,2-diol, is a benzenediol, Pyrocatechol was produced at a large scale industrially, mainly as precursors to pesticides, flavors, and fragrances. Its sulfonic acid is often present in the urine of many mammals.</p>Formule :C6H6O2Couleur et forme :SolidMasse moléculaire :110.11TSPO/Carbonic Anhydrase Modulator 1
<p>TSPO/Carbonic Anhydrase Modulator 1 (Compound 3) acts as a dual modulator of mitochondrial translocator protein and carbonic anhydrase, with a TSPOKi of 1.340 μM and a CAVII KA of 10.7 μM. It enhances neurosteroid production, increases BDNF gene expression, and demonstrates neuroprotective activity.</p>Formule :C35H51N3O3Couleur et forme :SolidMasse moléculaire :561.798hCAIX/XII-IN-14
<p>hCAIX/XII-IN-14 (Compound 1i) is an inhibitor of hCAIX and hCAXII, with Ki values of 9.4 nM for hCAII, 5.6 nM for hCAIX, and 6.3 nM for hCAXII.</p>Formule :C16H14F3N3O4SCouleur et forme :SolidMasse moléculaire :401.36Dorzolamide
CAS :<p>Dorzolamide is an anti-glaucoma agent and is a carbonic anhydrase inhibitor.</p>Formule :C10H16N2O4S3Degré de pureté :98%Couleur et forme :White Or Almost White Crystalline PowderMasse moléculaire :324.44Carbonic anhydrase inhibitor 32
<p>Carbonic anhydrase inhibitor32 (compound 5B) is an orally active, selective inhibitor of hCA (carbonic anhydrase) II/VII, with Ki values of 6.3 nM for hCA II, 10.1 nM for hCA VII, and 681 nM for hCA I. It shows potential for neuroprotection and anticonvulsant effects by reducing mTOR activation and increasing hippocampal KCC2 levels.</p>Formule :C17H16N6O3SCouleur et forme :SolidMasse moléculaire :384.41(E)-Dehydrodiconiferyl alcohol
CAS :<p>(E)-Dehydrodiconiferyl alcohol inhibits hCA IX/XII enzymes and blocks NF-κB nuclear translocation in healing tissues.</p>Formule :C20H22O6Couleur et forme :SolidMasse moléculaire :358.39Carbonic anhydrase inhibitor 31
<p>Carbonic anhydrase inhibitor31 is an mtCA2 inhibitor (Ki: 5.2 nM) that can be used in antituberculosis research.</p>Formule :C24H20N6O5SCouleur et forme :SolidMasse moléculaire :504.12159hCAIX-IN-17
<p>hCA IX-IN-1 inhibits hCA I/II/IX/XII with Ki of 331.4/28.4/9.4/17.8 nM, has anticancer properties.</p>Formule :C19H18N2O3SCouleur et forme :SolidMasse moléculaire :354.42VM4-037
CAS :<p>VM4-037 is a PET imaging agent used for carbonic anhydrase IX.</p>Formule :C26H29FN6O7S2Couleur et forme :SolidMasse moléculaire :620.67hCA/Wnt/β-catenin-IN-1
<p>hCA/Wnt/β-catenin-IN-1 (Compd 15) serves as an inhibitor with selective affinity for hCA isoforms II, IX, and XII, exhibiting K i values of 33.6, 24.1, and 6.8</p>Couleur et forme :Odour SolidCarbonic anhydrase inhibitor 29
<p>Carbonic anhydrase inhibitor29 (Compound 5d) is an inhibitor targeting carbonic anhydrase IX and XII, with an inhibition constant (Ki) of 26.6 nM for carbonic anhydrase IX and a Ki of 10.9 nM for carbonic anhydrase XII. Carbonic anhydrase inhibitor29 can be used in cancer research.</p>Couleur et forme :Odour SolidCAXII-IN-2
<p>CAXII-IN-2 (compound 3j) is a highly effective inhibitor of CAXII. It demonstrates inhibitory activity against CA IX and CAXII, with Ki values of 27.4 nM and 4.0 nM, respectively.</p>Formule :C16H13FNO4PCouleur et forme :SolidMasse moléculaire :333.05662hCAII-IN-8
CAS :<p>Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II.</p>Formule :C15H16N2O5SDegré de pureté :99.73%Couleur et forme :SoildMasse moléculaire :336.36hCAI/II-IN-10
<p>hCAI/II-IN-10 (Compound 5d) is an inhibitor of human carbonic anhydrase I and II (hCA I and hCA II), with IC50 values of 4.32 nM and 3.89 nM, respectively.</p>Formule :C24H17Cl2N3O3S2Couleur et forme :SolidMasse moléculaire :530.446DPP IV/hCA II-IN-1
CAS :<p>DPP IV/hCA II-IN-1: strong DPP IV & CA inhibitor, IC50=0.049μM (DPP IV), Ki=0.0361-3.034μM (CA II-IV).</p>Formule :C17H20N2O5SCouleur et forme :SolidMasse moléculaire :364.42Bendroflumethiazide
CAS :<p>Bendroflumethiazide (Naturetin) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)</p>Formule :C15H14F3N3O4S2Degré de pureté :98% - >99.99%Couleur et forme :Crystals From Dioxane SolidMasse moléculaire :421.41Carbonic anhydrase
CAS :<p>Carbonic anhydrase, a zinc enzyme in all life forms, converts CO2 to bicarbonate; studied for cancer, glaucoma, obesity, epilepsy.</p>Couleur et forme :SolidCarbonic anhydrase inhibitor 26
<p>Compound 6T, designated as Carbonic anhydrase inhibitor26, acts as an inhibitor of Carbonic Anhydrase II (Carbonic AnhydraseII), exhibiting an IC50 value of 9.10 ± 0.26 μM.</p>Formule :C17H14N6O4Couleur et forme :SolidMasse moléculaire :366.33AV22-149
<p>AV22-149 (compound 22) is an inhibitor of Carbonic Anhydrase .</p>Formule :C23H28F3N3O6S2Couleur et forme :SolidMasse moléculaire :563.61DOTA-XYIMSR-01
CAS :<p>DOTA-XYIMSR-01 is a molecular probe targeting CAIX, capable of being labeled with 177Lu for the treatment and localization of malignant gliomas. The uptake of [177Lu]Lu-XYIMSR-01 in U87MG tumors is 6.19% injected dose per gram (% ID/g), with a tumor-to-muscle uptake ratio of 20.14. In an orthotopic glioma model, co-administration with temozolomide significantly enhances survival rates and inhibits tumor growth in mice. DOTA-XYIMSR-01 shows potential for research in the field of cancer treatment.</p>Formule :C61H88N16O22S2Couleur et forme :SolidMasse moléculaire :1461.57Acesulfame
CAS :<p>Acesulfame inhibits CA9/12 and can be used to study inflammation-related diseases.</p>Formule :C4H5NO4SCouleur et forme :SolidMasse moléculaire :163.15Carbonic anhydrase inhibitor 18
<p>Carbonic anhydrase inhibitor18 (Compound 9) is an inhibitor of human carbonic anhydrase (hCA) isozymes, with Ki values of 604.8 nM for hCA I, 333.6 nM for hCA II, 1.9 nM for hCA IX, and 6.7 nM for hCA XII. Carbonic anhydrase inhibitor18 is applicable in cancer research.</p>Formule :C26H28N4O6S2Masse moléculaire :556.14503Girentuximab
CAS :<p>Girentuximab (G250) is an anti-carbonic anhydrase IX (CAIX) monoclonal antibody with anti-cancer activity for the study of uroepithelial carcinoma PET (ZiPUP).</p>Couleur et forme :LiquidMasse moléculaire :145.55 kDahCAIX/XII-IN-11
<p>hCAIX/XII-IN-11 (Compound 6c) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.7 μM for both isoforms. This compound is applicable in cancer research.</p>Formule :C13H10FN3O4Masse moléculaire :291.06553GZ22-4
<p>GZ22-4 is a near-infrared (NIR) fluorescent probe with a high affinity for carbonic anhydrase IX (CAIX), exhibiting a dissociation constant (Kd) of 0.2 nM. It is applicable in studies for visualizing CAIX-positive tumors.</p>Formule :C88H126F3N6NaO24S4Masse moléculaire :1858.75561SH7s
<p>SH7s is an effective carbonic anhydrase inhibitor, exhibiting Ki values of 15.9 nM for hCA IX and 55.2 nM for hCA XII. Additionally, SH7s acts as a hypoxia-mediated chemosensitizer in colorectal cancer cells.</p>Formule :C24H19ClF3N5O4SCouleur et forme :SolidMasse moléculaire :565.95hCA XII-IN-6
<p>Compound 4d, known as hCA XII-IN-6, is a potent inhibitor of human carbonic anhydrase XII (hCA XII) with a Ki value of 84.2 nM and exhibits anti-proliferative</p>Formule :C11H9N5O3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :323.35Chlorothiazide
CAS :<p>Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.</p>Formule :C7H6ClN3O4S2Degré de pureté :98.46% - 98.91%Couleur et forme :Crystals Physical Description Crystals; White Powder (Ntp 1992)Masse moléculaire :295.72Carbonic Anhydrase 12 Protein, Cynomolgus, Recombinant (His)
<p>Carbonic anhydrases (CAs) are a family of enzymes involved in the pH regulation of metabolically active cells/tissues.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :32.04 kDa (predicted). Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.Acetazolamide-d3
CAS :<p>Acetazolamide D3 is a deuterium-labeled Acetazolamide. Acetazolamide is a potent carbonic anhydrase inhibitor.</p>Formule :C4H6N4O3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :225.26M 12325
CAS :<p>M 12325 is used in the production of furosemide; rhinitis and occupational asthma were observed in workers from a lasamide production line.</p>Formule :C7H5Cl2NO4SCouleur et forme :White To Almost White Solid PowderMasse moléculaire :270.09Brinzolamide hydrochloride
<p>Brinzolamide (AL-4862) HCl selectively inhibits carbonic anhydrase II, reducing IOP for glaucoma research. IC50: 3.2 nM.</p>Couleur et forme :Solid4-(benzyloxy)benzene-1-sulfonamide
CAS :<p>4-(benzyloxy)benzene-1-sulfonamide is inhibitor of human recombinant CA-7.</p>Formule :C13H13NO3SDegré de pureté :97.54%Couleur et forme :SolidMasse moléculaire :263.31Zolamide
CAS :<p>Zolamide (CL 5343) may be used to prevent altitude sickness and reduce the symptoms.</p>Formule :C2H4N4O2S2Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :180.21EMAC10101d
CAS :<p>compound EMAC10101d, bearing a 2,4-dichorophenyl substituent in position 4 of the dihydrothiazole ring, was the most potent and selective toward hCA II with an</p>Formule :C17H15Cl2N3O2S2Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :428.36Benzenesulfonamide
CAS :<p>Benzenesulfonamide (Benzosulfonamide) ia an inhibitor of carbonic anhydrases.</p>Formule :C6H7NO2SDegré de pureté :99.42% - 99.99%Couleur et forme :White Crystalline PowderMasse moléculaire :157.19Dichlorphenamide
CAS :<p>Dichlorphenamide (Diclofenamide) is a carbonic anhydrase inhibitor that is used in the treatment of glaucoma.</p>Formule :C6H6Cl2N2O4S2Degré de pureté :96.87% - 97.25%Couleur et forme :Needles From Dimethylsulfoxide + Water SolidMasse moléculaire :305.16Benzolamide
CAS :<p>Benzolamide (CL 11366) inhibits carbonic anhydrase effectively and low-threshold calcium currents in hippocampal pyramidal neurons.</p>Formule :C8H8N4O4S3Degré de pureté :99.31%Couleur et forme :SolidMasse moléculaire :320.37Dichlorphenamide disodium
CAS :<p>Dichlorphenamide disodium: an oral carbonic anhydrase inhibitor that lowers eye pressure, promising for glaucoma study.</p>Formule :C6H6Cl2N2Na2O4S2Couleur et forme :SolidMasse moléculaire :351.12Dimethylfraxetin
CAS :<p>Dimethylfraxetin (6,7,8-Trimethoxycoumarin) is a Carbonic anhydrase inhibitor(Ki:0.0097 μM)</p>Formule :C12H12O5Degré de pureté :99.96% - ≥95%Couleur et forme :SolidMasse moléculaire :236.224-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide
CAS :<p>4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide (4-Amino-6-(trifluoromethyl)benzene-1,3-d) is a carbonic anhydrase inhibitor, used as a potential anti-</p>Formule :C7H8F3N3O4S2Degré de pureté :98.58%Couleur et forme :SolidMasse moléculaire :319.28Dorzolamide hydrochloride
CAS :<p>Dorzolamide hydrochloride (MK507 hydrochloride) is the hydrochloride salt form of dorzolamide, an inhibitor of carbonic anhydrase, a zinc-containing enzyme that</p>Formule :C10H17ClN2O4S3Degré de pureté :99.48% - 99.67%Couleur et forme :White Off-White Crystalline PowderMasse moléculaire :360.9Methyclothiazide
CAS :<p>Methyclothiazide (Aquatensen) is a substituted benzothiadiazide, used to treat high blood pressure and fluid retention caused by various conditions including</p>Formule :C9H11Cl2N3O4S2Degré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :360.242,3-dihydro-1H-indene-5-sulfonamide
CAS :<p>2,3-dihydro-1H-indene-5-sulfonamide is Carbonic anhydrase 12 (human) inhibitor.</p>Formule :C9H11NO2SDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :197.25Orthanilamide
CAS :<p>Orthanilamide (Orthanilamide) is a molecule containing the sulfonamide functional group attached to an aniline.</p>Formule :C6H8N2O2SDegré de pureté :99.72% - 99.96%Couleur et forme :White To Pale Cream Crystalline Powder Or CrystalsMasse moléculaire :172.2Indisulam
CAS :<p>Indisulam (E 7070) is a dual-action anticancer drug, blocking G1/S cell cycle transition by degrading cyclin E and activating p53/p21.</p>Formule :C14H12ClN3O4S2Degré de pureté :98.68% - 99.77%Couleur et forme :SolidMasse moléculaire :385.85U-104
CAS :<p>U-104 (NSC-213841) is an effective carbonic anhydrase (CA) inhibitor for CA IX( Ki=45.1 nM) and CA XII(Ki=4.5 nM).</p>Formule :C13H12FN3O3SDegré de pureté :98.76% - 99.88%Couleur et forme :SolidMasse moléculaire :309.32Ethoxzolamide
CAS :<p>Ethoxzolamide (L-643786) is a carbonic anhydrase inhibitor.</p>Formule :C9H10N2O3S2Degré de pureté :98.27% - 99.62%Couleur et forme :Crystals From Ethyl Acetate + Skellysolve B SolidMasse moléculaire :258.32Polmacoxib
CAS :<p>Polmacoxib, a first-class NSAID, dual inhibitor of CA and COX-2, may hinder colorectal cancer growth in mice.</p>Formule :C18H16FNO4SDegré de pureté :97.88%Couleur et forme :SolidMasse moléculaire :361.39Fluorometholone Acetate
CAS :<p>Fluorometholone Acetate (Oxylone acetate) is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.</p>Formule :C24H31FO5Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :418.50GV2-20
CAS :<p>GV2-20 is an effective carbonic anhydrase 2 inhibitors.</p>Formule :C15H13N3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :331.28Disulfamide
CAS :<p>Disulfamide: Oral carbonic anhydrase inhibitor, IC50 0.07 μM, diuretic by blocking Na+/HCO3- reabsorption.</p>Formule :C7H9ClN2O4S2Degré de pureté :98.1%Couleur et forme :SolidMasse moléculaire :284.74HCAIX-IN-2
CAS :<p>HCAIX-IN-2 (compound 9d) is a selective inhibitor of carbonic anhydrase and acts on hCA IX (Ki: 24.6 nM) and hCA XII (Ki: 45.3 nM).</p>Formule :C19H16N8O4SCouleur et forme :SolidMasse moléculaire :452.45hCAIX-IN-11
CAS :<p>hCAIX-IN-11 inhibits carbonic anhydrases IX & XII with Ki of 32.7 nM & 623.5 nM, respectively.</p>Formule :C21H15ClN4O3Couleur et forme :SolidMasse moléculaire :406.82hCAI/II-IN-1
CAS :<p>hCAI/II-IN-1 (Compound 3h) is a human carbonic anhydrase I and II (hCA I/II) inhibitor that acts on hCA I (IC50: 0.047 μM) and hCA II (IC50: 0.024 μM).</p>Formule :C18H29N5O3S3Couleur et forme :SolidMasse moléculaire :459.65hCAIX/XII-IN-2
CAS :<p>Compound 6a: Selective hCAIX/XII inhibitor; Ki: 30 nM (hCAIX), 3.6 nM (hCAXII); >10,000 nM (hCAI/II).</p>Formule :C19H14N2O4Couleur et forme :SolidMasse moléculaire :334.33CDK2-IN-12
CAS :<p>CDK2-IN-12 (10b), potent CDK2 inhibitor, IC50: 11.6 μM; inhibits hCA I/II/IX/XII, KI: 3534/638.4/44.3/48.8 nM; anti-cancer properties.</p>Formule :C20H17N9O2SCouleur et forme :SolidMasse moléculaire :447.47Clofenamide
CAS :<p>Clofenamide is a low-ceiling sulfonamide diuretic.</p>Formule :C6H7ClN2O4S2Couleur et forme :SolidMasse moléculaire :270.71hCAII-IN-2
CAS :<p>hCAII-IN-2 inhibits human carbonic anhydrases I, II, IX, XII with Ki values of 261.4, 3.8, 19.6, 45.2 nM respectively.</p>Formule :C25H18ClN5O4SCouleur et forme :SolidMasse moléculaire :519.96hCAIX/XII-IN-3
CAS :<p>Compound 6q inhibits hCAIX/CAXII; K i : hCAI >10000 nM, hCAII >10000 nM, hCAIX 66.2 nM, hCAXII 4.4 nM.</p>Formule :C20H13F3N2O4Couleur et forme :SolidMasse moléculaire :402.32CDK2-IN-11
CAS :<p>CDK2-IN-11 inhibits CDK2 (IC50: 6.4 μM) and targets hCA II, IX, XII (Ki: 23.4-56.3 nM); suited for cancer research.</p>Formule :C18H14ClN7O2SCouleur et forme :SolidMasse moléculaire :427.87hCA I-IN-1
CAS :<p>hCA I-IN-1 inhibits hCA I (Ki: 38.3 nM), II (Ki: 716.4 nM), IX (Ki: 940.1 nM), XII (Ki: 192.8 nM).</p>Formule :C27H23N5O4SCouleur et forme :SolidMasse moléculaire :513.57hCAXII-IN-3
CAS :<p>hCAXII-IN-3 (Compound 6o) is a selective inhibitor of human carbonic anhydrase XII (hCAXII) (Ki: 10.0 nM).</p>Formule :C26H20BrN5O3SCouleur et forme :SolidMasse moléculaire :562.44Carbonic anhydrase inhibitor 14
CAS :<p>CA inhibitor 14 blocks hCA I/II/IX/XII (K i of 1203/99.7/9.4/27.7 nM) and CDK2 (IC50: 20.3 μM), showing antitumor effects.</p>Formule :C18H17N7O2SCouleur et forme :SolidMasse moléculaire :395.44hCAXII-IN-5
CAS :<p>hCAXII-IN-5, or compound 6o, is a potent, selective hCAXII inhibitor with Ki values: hCAI & II >10000, hCAIX 286.1, hCAXII 1.0 nM.</p>Formule :C23H22N2O4Couleur et forme :SolidMasse moléculaire :390.43AHR-15010
CAS :<p>AHR-15010 is a novel anti-arthritic agent.</p>Formule :C10H16N2O8S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :356.37L-693612 HCl
CAS :<p>L-693612 HCl is an inhibitor of carbonic anhydrase.</p>Formule :C14H25ClN2O5S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :433.01hCAIX-IN-7
CAS :<p>hCAIX-IN-7 (6c) selectively inhibits tumor-related isoform hCAIX (KI: 410.6 nM) and weakly affects hCAI/II (KI: >10000 nM).</p>Formule :C18H12FNO3Couleur et forme :SolidMasse moléculaire :309.29Carbonic anhydrase inhibitor 13
CAS :<p>Carbonic anhydrase inhibitor 13 (compound 7) is a potent inhibitor of carbonic anhydrase (CA).</p>Formule :C17H15N5O3S2Couleur et forme :SolidMasse moléculaire :401.46hCAIX-IN-3
CAS :<p>hCAII-IN-3 (7e) selectively inhibits CA II/IX with Kis of 124.2/30.5 nM, showing promise for cancer treatment.</p>Formule :C21H21BrN6O4SCouleur et forme :SolidMasse moléculaire :533.4hCAIX-IN-14
CAS :<p>hCAIX-IN-14 is a potent inhibitor of human CA IX with a K i value of 134.8 nM .</p>Formule :C11H17ClN6O2SCouleur et forme :SolidMasse moléculaire :332.81Carbonic anhydrase inhibitor 7
CAS :<p>Potent hCA inhibitor; targets hCA IX, II, XII, I with Ki: 6.5, 7.1, 72.1, 255.8 nM respectively.</p>Formule :C23H17N3O5SCouleur et forme :SolidMasse moléculaire :447.46hCAXII-IN-1
CAS :<p>hCAXII-IN-1 selectively inhibits HCA IX/XII, promising for new cancer drug development.</p>Formule :C20H17NO5Couleur et forme :SolidMasse moléculaire :351.35Quinethazone
CAS :<p>Quinethazone is a thiazide diuretic used to treat hypertension. Common side effects include dizziness, dry mouth, nausea, and low potassium levels.</p>Formule :C10H12ClN3O3SCouleur et forme :Fibrous Crystals From 50% Acetone Physical Description Fibrous Crystals Or White Powder (Ntp 1992)Masse moléculaire :289.74hCAIX-IN-10
CAS :<p>"hCAIX-IN-10 (6i) selectively inhibits carbonic anhydrase IX/XII (Ki: 61.5/586.8 nM), markers in tumor cells, affecting acid-base balance."</p>Formule :C28H21N3O3SCouleur et forme :SolidMasse moléculaire :479.55hCAIX-IN-6
CAS :<p>6B and 14g inhibit tumor-associated HCA IX with low nanomolar potency; 6K targets HCA XII. All are potential cancer drug leads.</p>Formule :C18H12N2O4SCouleur et forme :SolidMasse moléculaire :352.36DTP348
CAS :<p>DTP348: Oral carbonic anhydrase IX inhibitor & hypoxic cell radiosensitizer with sulfamide & 5-nitroimidazole components.</p>Formule :C6H11N5O4SCouleur et forme :SolidMasse moléculaire :249.25Carbonic anhydrase inhibitor 11
CAS :<p>Potent carbonic anhydrase inhibitor VI targets CA II, IX, XII with Ki: 40, 39, 900 nM respectively.</p>Formule :C19H15F3N4O3S2Couleur et forme :SolidMasse moléculaire :468.47hCAIX/XII-IN-4
CAS :<p>hCAIX/XII-IN-4 inhibits CAIX/XII with Ki: 4.5 nM (CAXII), 23.6 nM (CAIX), and >10000 nM (CAI/CAII).</p>Formule :C20H16N2O5Couleur et forme :SolidMasse moléculaire :364.35hCAXII-IN-4
CAS :<p>hCAXII-IN-4 is a selective and potent CA XII inhibitor with a Ki value of 6.4 nM for human CA XII.</p>Formule :C22H27N5O6SCouleur et forme :SolidMasse moléculaire :489.54hCAI/II-IN-2
CAS :<p>hCAI/II-IN-2 (2b) inhibits hCA I/II (Ki: 40.97 nM, 15.15 nM) and IX (61.88 nM), fights AMS with anti-hypoxic effects, but has low cellular activity.</p>Formule :C12H12N4O5S2Couleur et forme :SolidMasse moléculaire :356.38hCA IX-IN-2
<p>hCA IX-IN-2 is a highly potent and selective inhibitor of hCA IX, exhibiting an inhibition constant (K I) value of 32.1 nM and demonstrating anti-proliferative</p>Formule :C23H24N2O4STeCouleur et forme :SolidMasse moléculaire :552.11hCAI/II-IN-3
CAS :<p>"hCAI/II-IN-3 (compound 5b) is a potent dual hCA I/II inhibitor with Ki: 51.25nM (I), 13.15nM (II), helps treat AMS."</p>Formule :C16H18N4O4S2Couleur et forme :SolidMasse moléculaire :394.47hCAIX/XII-IN-6
<p>hCAIX/XII-IN-6: Oral carbonic anhydrase inhibitor, targets hCA I/II/IV/IX/XII, aids rheumatoid arthritis research. Ki: 6697/2950/4093/4.1/7.7 nM.</p>Formule :C26H23N3O6S4Couleur et forme :SolidMasse moléculaire :601.74hCAII-IN-1
CAS :<p>hCAII-IN-1 (7f) inhibits CA II/IX with Kis 1.2 nM/113.6 nM, potential for cancer treatment.</p>Formule :C21H21BrN6O4SCouleur et forme :SolidMasse moléculaire :533.4hCAIX-IN-8
CAS :<p>hCAIX-IN-8, a selective hCAIX inhibitor, IC50: 0.024 μM. Also affects CAII, CAVA (IC50s: 1.99, 1.10 μM), limits cell migration, and induces apoptosis.</p>Formule :C19H16N4O6Couleur et forme :SolidMasse moléculaire :396.35hCAXII-IN-2
CAS :<p>hCAXII-IN-2 is a potent inhibitor of hCA XII (Ki: 84.2 nM) and hCA IX (Ki: 268.5 nM), with low activity on hCA I/II.</p>Formule :C21H18ClN3O4Couleur et forme :SolidMasse moléculaire :411.84hCA I-IN-2
CAS :<p>hCA I-IN-2 (6d) inhibits hCA I (Ki: 18.8 nM) more selectively over II, IX, XII (Ki: 375.1, 1721, 283.9 nM).</p>Formule :C26H20BrN5O3SCouleur et forme :SolidMasse moléculaire :562.44FC11409B
CAS :<p>FC11409B is a CAIX inhibitor, inhibiting breast cancer invasion and metastasis.</p>Formule :C29H23BF4N2O3SCouleur et forme :SolidMasse moléculaire :566.38hCAI/II-IN-4
CAS :<p>hCAI/II-IN-4 inhibits hCA I & II (Ki: 16.95 & 15.22 nM), hCA IX (Ki: 27.04 nM), has anti-hypoxia benefits and is low-toxic for AMS research.</p>Formule :C15H15N3O5S2Couleur et forme :SolidMasse moléculaire :381.43Methazolamide-d6
CAS :<p>Methazolamide-d6 is a GC/LC-MS standard for measuring methazolamide, a glaucoma drug that lowers eye pressure and fluid, reduces seizures, and combats ROS.</p>Formule :C5H2D6N4O3S2Couleur et forme :SolidMasse moléculaire :242.31L 662583
CAS :<p>L 662583 is a topical inhibitor of carbonic anhydrase.</p>Formule :C13H17ClN2O5S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :412.93L-693612
CAS :<p>L-693612 is an inhibitor of carbonic anhydrase.</p>Formule :C14H24N2O5S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :396.55L 645151
CAS :<p>L 645151 is an inhibitor of lipophilic CA.</p>Formule :C12H14N2O4S2Couleur et forme :SolidMasse moléculaire :314.38hCAIX-IN-5
CAS :<p>hCAIX-IN-5 was a selective hCAIX inhibitor, inhibiting hCAI, hCAII, hCAIV, and hCAIX with Ki values of >10000, >10000, 130.7, and 829.1 nM, respectively.</p>Formule :C18H12FNO3Degré de pureté :99.26%Couleur et forme :SolidMasse moléculaire :309.29WES-1
CAS :<p>WES-1 (Compound 8g), a carbonic anhydrase IX inhibitor (Ki: 55.9 μM), exhibits broad-spectrum antiproliferative activity against various cancer cell lines,</p>Formule :C20H20N4O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :396.46hCAI/II-IN-6
CAS :<p>hCAI/II-IN-6 is a selective and orally active inhibitor of human carbonic anhydrase (CA).</p>Formule :C19H24N4O3SDegré de pureté :97.07%Couleur et forme :SolidMasse moléculaire :388.48hCAII-IN-9
CAS :<p>hCAII-IN-9 inhibits hCA II/IX/XII with IC50s of 1.18, 0.17, 2.99 μM; not BBB permeable.</p>Formule :C15H16ClN3O5S2Degré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :417.89Sultiame
CAS :<p>Sultiame is an inhibitor of carbonic anhydrase. Sultiame can be used in antiepileptic research.</p>Formule :C10H14N2O4S2Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :290.36Carbonic anhydrase inhibitor 6
CAS :<p>Carbonic anhydrase inhibitor 6 is an hCA inhibitor that inhibits hCA IX, hCA II, hCA XII, and hCA I. It is used in the study of lupus erythematosus.</p>Formule :C26H25N3O5SDegré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :491.56hCAIX/XII-IN-8
CAS :<p>hCAIX/XII-IN-8 (compound 3g) is a potent inhibitor of the human carbonic anhydrases (CAs) IX and XII, with inhibition constants (K i) of 8.5 nM for CA IX and 6.</p>Formule :C16H13Cl2N5O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :426.28Carbonic anhydrase inhibitor 12
CAS :<p>CA Inhibitor 12 strongly blocks CA II (K_i 1.72 nM), also inhibits CA I (271 nM), shows anticancer effects.</p>Formule :C27H22BrN5O5S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :640.53N-Desethyl Brinzolamide oxalate
CAS :<p>N-Desethyl Brinzolamide oxalate functions as a dual inhibitor targeting Carbonic anhydrase II and Carbonic anhydrase IV, exhibiting inhibitory concentrations (IC50) of 1.28 nM and 128 nM, respectively [1].</p>Formule :C12H19N3O9S3Couleur et forme :SolidMasse moléculaire :445.49COX-2-IN-30
CAS :<p>COX-2-IN-30, a benzenesulfonamide derivative, is an orally active, dual inhibitor of cyclooxygenase-2 (COX-2; IC50 = 49 nM) and cyclooxygenase-1 (COX-1; IC50 =</p>Formule :C17H16N6O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :384.41hCAIX-IN-16
CAS :<p>hCAIX-IN-16 (Compound 12d), an inhibitor of hCA IX, exhibits inhibition constants (K i) of 190.0 nM for hCA IX and 187.9 nM for hCA XII.</p>Formule :C20H20N8O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :436.49ALP/Carbonic anhydrase-IN-1
CAS :<p>Compound 1e, also known as ALP/Carbonic anhydrase-IN-1, is a dual inhibitor targeting both carbonic anhydrase (CA) isozymes II, IX, and XII, as well as alkaline</p>Formule :C15H16N2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :224.3CAXII-IN-1
CAS :<p>CAXII-IN-1, antitumor, selectively inhibits CA XII with Ki of 3.8 nM for hCA XII and 56 nM for hCA IX.</p>Formule :C13H7Cl2NO3SCouleur et forme :SolidMasse moléculaire :328.17hCAIX-IN-15
CAS :<p>hCAIX-IN-15 is a potent inhibitor of human carbonic anhydrase IX (hCA IX) with an inhibition constant (Ki) of 38.8 nM, exhibiting broad-spectrum anticancer</p>Formule :C18H14FN7O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :411.41CAII-IN-2
<p>CAII-IN-2 (3g): potent, selective CA-II inhibitor; IC50-12.1 μM for bovine CA-II; valuable in CA-related disorder research.</p>Formule :C18H19BrN4SCouleur et forme :SolidMasse moléculaire :403.34Carbonic anhydrase inhibitor 5
<p>Potent hCA inhibitor: targets hCA II, IX & XII with IC50s of 42.9, 47.6, & 6.7 nM respectively.</p>Formule :C24H20ClN3O3SCouleur et forme :SolidMasse moléculaire :465.95Carbonic anhydrase inhibitor 9
<p>Carbonic anhydrase inhibitor 9 targets hCA II and IX with Ki of 56.4 and 56.9 nM respectively; shows antiproliferative activity.</p>Formule :C22H20BrN5O4SCouleur et forme :SolidMasse moléculaire :530.39hCAII-IN-5
CAS :<p>hCAII-IN-5 (compound 12h) is a potent, selective inhibitor of human carbonic anhydrase II (hCA II) with an inhibition constant (IC50) of 4.55 µM [1].</p>Formule :C29H18N2O7Couleur et forme :SolidMasse moléculaire :506.46hCAII-IN-3
<p>hCAII-IN-3 inhibits key hCA isoforms with Ki: hCA I (403.8 nM), hCA II (5.1 nM), hCA IX (10.2 nM), hCA XII (5.2 nM); shows anticancer potential.</p>Formule :C17H21N3O3SCouleur et forme :SolidMasse moléculaire :347.43Valerate sodium
CAS :<p>Valerate sodium is a potential Carbonic anhydrase 1/2 inhibitor for biochemical experiments.</p>Formule :C5H9NaO2Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :124.11O-Desmethyl Brinzolamide hydrochloride
CAS :<p>O-Desmethyl Brinzolamide hydrochloride (compound 6a), a potent metabolite derived from Brinzolamide, serves as a carbonic anhydrase (CA) inhibitor. It exhibits a dissociation constant (Kd) of 0.136 nM for CA II and an inhibitory concentration (IC50) of 165 nM for CA IV [1].</p>Formule :C11H20ClN3O5S3Couleur et forme :SolidMasse moléculaire :405.94hCAIX/XII-IN-15
CAS :<p>hCAIX/XII-IN-15 (Compound 17β) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.42 and 4.37 μM, respectively. It demonstrates a pro-apoptotic effect in multiple myeloma cells.</p>Formule :C17H18O4SCouleur et forme :SolidMasse moléculaire :318.387Carbonic anhydrase inhibitor 4
<p>CA inhibitor 4, photoprobe; targets hCA I-XIV; Ki: 640-1166 nM.</p>Formule :C21H18N2O4SCouleur et forme :SolidMasse moléculaire :394.44Perfluorohexane sulfonamide
CAS :<p>Perfluorohexane sulfonamide (FHxSA) serves as an inhibitor of carbonic anhydrase (CA), effectively inhibiting bovine CA and human CAII with IC50 values of 0.122 and 1.38 μM, respectively. Additionally, it acts as a delayed-action insecticide for controlling red imported fire ants (Solenopsis invicta). Furthermore, Perfluorohexane sulfonamide is considered a potential environmental pollutant.</p>Formule :C6H2F13NO2SCouleur et forme :SolidMasse moléculaire :399.13AChE/CA I-IN-1
<p>AChE/CA I-IN-1 (Compound 2g) acts as an inhibitor for both AChE and hCA I, with Ki values of 1.85 µM and 0.53 µM, respectively. It has shown potential applications in the research of Alzheimer's disease, glaucoma, and epilepsy.</p>Formule :C14H19NO6SCouleur et forme :SolidMasse moléculaire :329.374-Acetylphenylboronic acid
CAS :<p>4-Acetylphenylboronic acid acts as an effective inhibitor targeting carbonic anhydrase II (CAII), displaying inhibitory concentrations (IC50) of 246 μM for bovine CAII (bCA II) and 281.40 μM for human CAII (hCA II).</p>Formule :C8H9BO3Couleur et forme :SolidMasse moléculaire :163.97CA IX-IN-1
<p>CA IX-IN-1 (compound 12g) is a potent and highly selective hCA IX inhibitor (IC50: 7 nM) that exhibits antitumour effects.</p>Formule :C16H22N4O8SCouleur et forme :SolidMasse moléculaire :430.43hCAI/II/XII-IN-1
CAS :<p>hCAI/II/XII-IN-1 (compound 7) is an inhibitor of human carbonic anhydrases hCAI, hCAII, and hCAXII, with Ki values of 78.5 nM, 9.1 nM, 605 nM, 7.7 nM, and 3.7 nM.</p>Formule :C12H12N2O2SCouleur et forme :SolidMasse moléculaire :248.301CA IX-IN-3
CAS :<p>CAIX-IN-3 (Compound 27) is a selective and potent inhibitor of carbonic anhydrase IX (CAIX), with an IC50 of 0.48 nM.</p>Formule :C21H19N5O4S2Couleur et forme :SolidMasse moléculaire :469.537Carbonic anhydrase inhibitor 17
CAS :<p>Carbonic anhydrase inhibitor 17 (compound 7c) is a pyrazine-based sulfonamide that acts as a carbonic anhydrase II inhibitor, with an IC50 value of 0.63 nM.</p>Formule :C18H15ClN4O3S2Masse moléculaire :434.92Carbonic anhydrase inhibitor 16
CAS :<p>Carbonic anhydrase inhibitor 16 (compound 1) is a CA I/CA II inhibitor with potential antiviral activity, used in virus infection studies.</p>Formule :C14H10N2O4SDegré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :302.31CAII-IN-1
<p>CAII-IN-1 (3n) is a selective bovine CA-II inhibitor with 10.3 μM IC50, used in carbonic anhydrase disorder studies.</p>Formule :C19H21FN4SCouleur et forme :SolidMasse moléculaire :356.46Sulclamide
CAS :<p>Sulclamide, a sulfamoylbenzoic acid derivative, exhibits diuretic activity and functions as an inhibitor of carbonic anhydrase [1].</p>Formule :C7H7ClN2O3SCouleur et forme :SolidMasse moléculaire :234.66hCAVII/IX-IN-1
CAS :<p>hCAVII/IX-IN-1 (compound 4) functions as an inhibitor of hCAVII/IX, exhibiting Ki values of 56.5 nM and 38.2 nM, respectively. It is applicable in the field of cancer research.</p>Formule :C7H7N3O2S2Couleur et forme :SolidMasse moléculaire :229.279CAII-IN-3
<p>CAII-IN-3, a thiosemicarbazone, potently inhibits CA-II with an IC50 of 13.4 μM.</p>Formule :C18H18F2N4SCouleur et forme :SolidMasse moléculaire :360.42β-Glucuronidase/hCAII-IN-2
<p>β-Glucuronidase/hCAII-IN-2 is a potent inhibitor of β-glucuronidase and hCA II, and their IC50 values were 670.7 μM and 21.77 μM, respectively.</p>Formule :C31H23NO8Couleur et forme :SolidMasse moléculaire :537.52Carbonic anhydrase inhibitor 19
CAS :<p>Carbonic anhydrase inhibitor19 (compound 26a) targets glaucoma-associated isozymes hCA II and hCA XII, with inhibition constants (Kis) of 9.4 nM and 6.7 nM, respectively. This compound is effective in reducing intraocular pressure.</p>Formule :C23H25N3O6S2Masse moléculaire :503.59Carbonic anhydrase inhibitor 2
CAS :<p>Compound 7c inhibits carbonic anhydrase II, lowering intraocular pressure in glaucomatous rabbits.</p>Formule :C12H16N4O6SCouleur et forme :SolidMasse moléculaire :344.34α-Glucosidase-IN-63
CAS :<p>α-Glucosidase-IN-63 (Compound 4d) serves as an α-Glucosidase inhibitor with an IC 50 value of 0.44 μM. Additionally, it exhibits inhibitory activity against hCA II, demonstrating a K i of 7.0 nM. The compound is also effective when administered orally. [1]</p>Formule :C16H12FN3O3S2Couleur et forme :SolidMasse moléculaire :377.41hCAII-IN-4
CAS :<p>hCAII-IN-4 (Compound 12j) is a potent inhibitor of human carbonic anhydrase II (hCA II), exhibiting an inhibitory concentration (IC50) of 7.78 μM.</p>Formule :C31H23NO9Couleur et forme :SolidMasse moléculaire :553.52Carbonic anhydrase inhibitor 8
<p>R-13, a carbonic anhydrase inhibitor, has Ki of 60.7 nM (hCA I), 320.7 nM (hCA II), and 2298 nM (hCA IV).</p>Formule :C20H25N3O4SCouleur et forme :SolidMasse moléculaire :403.5Carbonic anhydrase inhibitor 3
<p>Carbonic anhydrase inhibitor 3 (compound 11g) is an inhibitor of carbonic anhydrase II that reduces the intraocular pressure in glaucomatous rabbits [1].</p>Formule :C15H17N3O3SCouleur et forme :SolidMasse moléculaire :319.38hCA XII/II/IX-IN-1
<p>hCA XII/II/IX-IN-1 inhibits hCA I/II/IX/XII (IC50: 2.6, 0.004, 0.005, 0.001 μM) with anticancer properties.</p>Formule :C25H34N4O7SCouleur et forme :SolidMasse moléculaire :534.63Carbonic anhydrase inhibitor 10
<p>CA inhibitor 10 targets MCF-7 cells, IC50: 11.9 μM; potent h CA IX inhibitor, Ki: 6.2 nM. Anti-cancer research.</p>Formule :C14H17N5O3SCouleur et forme :SolidMasse moléculaire :335.38β-Glucuronidase/hCAII-IN-1
CAS :<p>β-Glucuronidase/hCAII-IN-2 (Compound 12e) is a compound that effectively inhibits both β-glucuronidase and human Carbonic Anhydrase II (hCA II), exhibiting IC50</p>Formule :C30H21NO9Couleur et forme :SolidMasse moléculaire :539.49NSC 828467
<p>NSC 828467 is one of the top five CA-IX inhibitors with significant in vitro anticancer activity (IC50: 27.2 nM).</p>Formule :C21H19N9O2SCouleur et forme :SolidMasse moléculaire :461.5hCA VB-IN-1
<p>hCA VB-IN-1 (compound 15) is a potent and selective inhibitor of hCA VB (carbonic anhydrase) with a KI of 515.7 nM [1].</p>Formule :C9H13N3O4SCouleur et forme :SolidMasse moléculaire :259.28

