Benzthiazide

CAS : 91-33-8

Ref. TM-T0782

Informations sur le produit

• Nom: Benzthiazide
• Synonymes: Aquatag, Lemazide, Dihydrex, 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3-[(benzylthio)methyl]-6-chloro-, 1,1-dioxide, 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-[[(phenylmethyl)thio]methyl]-, 1,1-dioxide, 3-Benzylthiomethyl-6-chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 3-Benzylthiomethyl-6-chloro-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide, 3-Benzylthiomethyl-6-chloro-7-sulfamyl-1,2,4-benzothiadiazine-1,1-dioxide, 3-Benzylthiomethyl-6-chloro-7-sulfamyl-2H-1,2,4-benzothiadiazine 1,1-dioxide, 3-[(Benzylthio)methyl]-6-chloro-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 3-[(benzylsulfanyl)methyl]-6-chloro-4H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, Aquatag, Benzothiazide, Benzotiazida, Benzthazide, Benzthiazid, Dihydrex, Diucen, Diucene, Edemex, ExNa, Exosalt, Fovane, Freeuril, HyDrine, Lemazide, P 1393, Pfizer 1393, Proaqua, Regulon, Urese
• CAS: 91-33-8

Description

Benzthiazide (Lemazide) is used in the therapy of edema and hypertension. Like other thiazides, benzthiazide accelerates water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue.

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 431.94
• Formule: C₁₅H₁₄ClN₃O₄S₃
• Degré de pureté: 99.79%
• Couleur/Forme: Crystals From Acetone Solid