PPAR
Les récepteurs activés par les proliférateurs des peroxysomes (PPARs) sont un groupe de protéines réceptrices nucléaires qui fonctionnent comme des facteurs de transcription régulant l'expression des gènes impliqués dans le métabolisme, en particulier le stockage des acides gras et le métabolisme du glucose. Les inhibiteurs des PPARs sont des outils importants pour étudier les troubles métaboliques tels que le diabète, l'obésité et les maladies cardiovasculaires. Ces inhibiteurs peuvent moduler le métabolisme des lipides, la sensibilité à l'insuline et l'inflammation, ce qui les rend précieux dans la recherche thérapeutique. Chez CymitQuimica, nous proposons une gamme d'inhibiteurs de PPARs pour soutenir vos recherches sur les maladies métaboliques, l'endocrinologie et le développement de médicaments.
170 produits trouvés pour "PPAR"
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GW590735
CAS :GW590735: PPARα agonist, EC50=4 nM, >500x selective over PPARδ/γ, for dyslipidemia research.Formule :C23H21F3N2O4SDegré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :478.48GQ-16
CAS :GQ-16 is a partial agonist of PPARγ with a Ki of 160 nM. GQ-16 reduces adipogenic actions and promotes insulin Sensitization without weight gain.Formule :C19H16BrNO3SDegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :418.3Ref: TM-T21955
10mg39,00€25mg80,00€50mg116,00€100mg187,00€200mg280,00€500mg449,00€1mL*10mM (DMSO)35,00€Balaglitazone
CAS :Balaglitazone is a PPARγ agonist that regulates blood glucose and is used in studies of heart failure and myocardial infarction.Formule :C20H17N3O4SDegré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :395.43CP-868388 free base
CAS :CP-868388 free base (CP-868388) is a PPARα agonist with hypolipidemic and anti-inflammatory activity and is used in the study of dyslipidemia.Formule :C26H33NO5Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :439.54PPAR α/PPARA Protein, Mouse, Recombinant (His)
PPAR alpha/PPARA Protein, Mouse, Recombinant (His) is expressed in E.Couleur et forme :Lyophilized PowderMasse moléculaire :31.49 kDa (predicted)Ref: TM-TMPY-06837
5µg109,00€10µg174,00€20µg289,00€50µg576,00€100µg1.017,00€200µg1.718,00€500µg4.207,00€PPAR α/PPARA Protein, Human, Recombinant (His)
PPAR alpha/PPARA Protein, Human, Recombinant (His) is expressed in E.Couleur et forme :Lyophilized PowderMasse moléculaire :31.36 kDa (predicted)Ref: TM-TMPY-06830
5µg110,00€10µg177,00€20µg289,00€50µg576,00€100µg1.007,00€200µg1.700,00€500µg3.631,00€SR 16832
CAS :SR 16832: Dual-site PPARγ inhibitor; outperforms GW 9662, T 0070907 in ligand binding, transcription inhibition.Formule :C17H12ClN3O4Degré de pureté :99.6%Couleur et forme :SolidMasse moléculaire :357.75GW0742
CAS :GW0742 (GW610742) is an effective and specific PPARδ agonist (EC50: 1 nM/1.1 μM/2 μM, for human PPARδ/α/γ).Formule :C21H17F4NO3S2Degré de pureté :99.75% - 99.85%Couleur et forme :SolidMasse moléculaire :471.49CDDO-Im
CAS :CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).Formule :C34H43N3O3Degré de pureté :98.3% - 99.61%Couleur et forme :SolidMasse moléculaire :541.72Ref: TM-TQ0120
1mg34,00€5mg74,00€10mg105,00€25mg200,00€50mg319,00€100mg485,00€500mg1.035,00€1mL*10mM (DMSO)89,00€Angeloylgomisin H
CAS :Angeloylgomisin H shows moderate cytotoxic activities with IC50 values ranging from 100 to 200 ug/mL against MCF7, HEK293 and CAL27 cell lines.Formule :C28H36O8Degré de pureté :99.84% - 99.95%Couleur et forme :SolidMasse moléculaire :500.58Ref: TM-TN1018
1mg52,00€5mg111,00€10mg172,00€25mg290,00€50mg420,00€100mg577,00€1mL*10mM (DMSO)149,00€Cinnamyl alcohol
CAS :Cinnamyl alcohol (Styryl Carbinol) readily autoxidizes upon air exposure, and forms strong sensitizers as determined by the local lymph node assay.Formule :C9H10ODegré de pureté :99.00%Couleur et forme :Colourless LiquidMasse moléculaire :134.18SC-236
CAS :SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively).Formule :C16H11ClF3N3O2SDegré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :401.79Clofibrate
CAS :Clofibrate (Clofibrato) is an aryloxyisobutyric acid derivate with antihyperlipidemic activity.Formule :C12H15ClO3Degré de pureté :98.77%Couleur et forme :Oil LiquidMasse moléculaire :242.70Raspberry ketone
CAS :1.Formule :C10H12O2Degré de pureté :99.84% - 99.89%Couleur et forme :White Solid CrystallineMasse moléculaire :164.2Fisetin
CAS :Fisetin belongs to a group of natural flavonols with anti-inflammatory, antioxidant, anti-tumor, anti-aging and neuroprotective effects. Cost effective and quality assured.Formule :C15H10O6Degré de pureté :94.14% - 99.05%Couleur et forme :Yellow To Brown Crystalline PowderMasse moléculaire :286.24Ginsenoside Rh1
CAS :Ginsenoside Rh1 (Sanchinoside B2) , one of the main constituents of Panax ginseng, exhibits anti-inflammatory effect.Formule :C36H62O9Degré de pureté :99% - 99.64%Couleur et forme :SolidMasse moléculaire :638.87Alpinetin
CAS :Alpinetin: antibacterial, anti-inflammatory, boosts HepG2 sensitivity to CDDP, fights hepatoma/pancreatic cancer, inhibits cell growth & activates caspases.Formule :C16H14O4Degré de pureté :98.39%Couleur et forme :SolidMasse moléculaire :270.28Oleuropein
CAS :Oleuropein is an antioxidant polyphenol isolated from olive leaf.Formule :C25H32O13Degré de pureté :98% - 99.95%Couleur et forme :Brown PowderMasse moléculaire :540.51EPI-001
CAS :EPI-001 is an androgen receptor N-terminal domain antagonist with IC50 of ～6 μM and a selective PPAR-gamma modulator.Formule :C21H27ClO5Degré de pureté :99% - 99.67%Couleur et forme :SolidMasse moléculaire :394.89Ref: TM-T6829
2mg35,00€5mg50,00€10mg77,00€25mg127,00€50mg202,00€100mg303,00€200mg449,00€1mL*10mM (DMSO)51,00€Glabridin
CAS :Glabridin aids in diabetes by reducing inflammation and glucose levels and may prevent liver cancer spread.Formule :C20H20O4Degré de pureté :99.78% - 99.99%Couleur et forme :Light Yellow Powder Insoluble In WaterMasse moléculaire :324.37Convallatoxin
CAS :Convallatoxin is a natural product.Formule :C29H42O10Degré de pureté :99.27% - 99.53%Couleur et forme :Prisms From Methanol + Ether SolidMasse moléculaire :550.64Elafibranor
CAS :Elafibranor (GFT505) is an agonist of the peroxisome proliferator-activated receptor-α (PPAR-α) and peroxisome proliferator-activated receptor-δ (PPAR-δ) withFormule :C22H24O4SDegré de pureté :98.42% - 98.78%Couleur et forme :SolidMasse moléculaire :384.49Ref: TM-T4408
2mg35,00€5mg52,00€10mg70,00€25mg110,00€50mg177,00€100mg283,00€200mg426,00€1mL*10mM (DMSO)57,00€Methyl oleanonate
CAS :3-Oxoolean-12-en-28-oic acid methyl ester is a triterpenoid PPARγ agonist isolated from Pistacia with anticancer properties.Formule :C31H48O3Degré de pureté :98.99%Couleur et forme :SolidMasse moléculaire :468.71Gypenoside XLIX
CAS :Extracted from whole herb of Gynostemsma pentaphyllum(Thunb.)Mak.;Store the product in sealed, cool and dry conditionFormule :C52H86O21Degré de pureté :97.05% - 99.78%Couleur et forme :SolidMasse moléculaire :1047.23NPC 15199
CAS :NPC 15199 (FMOC-L-Leucine) is an anti-inflammatory agent.
Formule :C21H23NO4Degré de pureté :99.93% - 99.94%Couleur et forme :White Crystalline PowderMasse moléculaire :353.41AMG131
CAS :AMG131 (CHS 131) , is a novel, non-thiazolidinedione (TZD), selective peroxisome proliferator-activated receptor (PPAR)gamma modulator, which can be used forFormule :C21H12Cl4N2O3SDegré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :514.21MK-886
CAS :MK-886 (L 663536) is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP).Formule :C27H34ClNO2SDegré de pureté :99.23% - 99.84%Couleur et forme :SolidMasse moléculaire :472.08Ref: TM-T6893
1mg35,00€5mg70,00€10mg111,00€25mg216,00€50mg354,00€100mg540,00€200mg772,00€1mL*10mM (DMSO)72,00€BMS-687453
CAS :BMS-687453 is a potent and selective PPAR alpha agonist, with an EC(50) of 10 nM for human PPARalpha and approximately 410-fold selectivity vs human PPARgammaFormule :C22H21ClN2O6Degré de pureté :99.4%Couleur et forme :SolidMasse moléculaire :444.86Ref: TM-T5532
1mg44,00€2mg57,00€5mg93,00€10mg137,00€25mg268,00€50mg409,00€100mg620,00€1mL*10mM (DMSO)92,00€Oroxin A
CAS :Oroxin A (Baicalein 7-O-glucoside) has antitussive and expectorant effects.Formule :C21H20O10Degré de pureté :98.05% - 99.74%Couleur et forme :SolidMasse moléculaire :432.38Ref: TM-T5S0788
1mg43,00€5mg87,00€10mg135,00€25mg221,00€50mg349,00€100mg507,00€200mg720,00€1mL*10mM (DMSO)95,00€G3335 Acetate
G3335 Acetate was discovered to be a novel PPARgamma antagonist.Formule :C18H23N3O7Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :393.39Ref: TM-T21598L
5mg55,00€10mg82,00€25mg126,00€50mg182,00€100mg273,00€200mg409,00€500mg677,00€1mL*10mM (DMSO)79,00€LJ570
CAS :LJ570 is the first PPARα/γ dual agonist (PPARα,PPARγ with EC50s of 1.05 and 0.12 μM, respectively[)Formule :C27H22O3Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :394.46Ref: TM-T8374
1mg138,00€2mg202,00€5mg311,00€10mg445,00€25mg680,00€50mg888,00€100mg1.234,00€500mg2.475,00€1mL*10mM (DMSO)334,00€Ciprofibrate
CAS :Ciprofibrate (Win35833) is a fibrate derivative with antilipidemic activity.Formule :C13H14Cl2O3Degré de pureté :99.63% - >99.99%Couleur et forme :White Or Almost White Crystalline PowderMasse moléculaire :289.15L-165041
CAS :L-165041 is a potent and selective agonist of the nuclear receptor PPARβ and PPARδ(Ki = 9 nM, EC50 = ~500 nM ,respectively)Formule :C22H26O7Degré de pureté :97.97%Couleur et forme :SolidMasse moléculaire :402.44GSK0660
CAS :GSK0660 is an antagonist and inverse agonist of PPARβ/δ.Formule :C19H18N2O5S2Degré de pureté :99.26% - ≥95%Couleur et forme :SolidMasse moléculaire :418.49Ref: TM-T2674
2mg44,00€5mg65,00€10mg99,00€25mg175,00€50mg349,00€100mg520,00€500mg1.134,00€1mL*10mM (DMSO)65,00€OPHIOPOGONIN D
CAS :Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.Formule :C44H70O16Degré de pureté :99.46% - ≥95%Couleur et forme :SolidMasse moléculaire :855.02XMD8-87
CAS :XMD8-87 (ACK1-B19), a TNK2 inhibitor, strongly blocks TNK2 phosphorylation and mutations in tumors.Formule :C24H27N7O2Degré de pureté :98.05% - 99.89%Couleur et forme :SolidMasse moléculaire :445.52Ref: TM-T3709
2mg44,00€5mg70,00€10mg98,00€25mg178,00€50mg290,00€100mg480,00€500mg1.161,00€1mL*10mM (DMSO)84,00€GW 501516
CAS :GW 501516 (Endurobol) is a effective and highly specifc PPARβ/δ agonist (EC50: 1 nM), with 1000-fold selectivity over hPPARα/γ.Formule :C21H18F3NO3S2Degré de pureté :98.91% - 99.64%Couleur et forme :White SolidMasse moléculaire :453.50XMD16-5
CAS :XMD16-5 blocks TNK2, linked to advanced lung/prostate cancers and breast cancer metastasis in mice; disrupts signaling in several tumors.Formule :C23H24N6O2Degré de pureté :98.89% - 99.98%Couleur et forme :SolidMasse moléculaire :416.48Ref: TM-T3710
1mg42,00€2mg52,00€5mg95,00€10mg137,00€25mg213,00€50mg394,00€100mg583,00€500mg1.243,00€1mL*10mM (DMSO)95,00€Astaxanthin
CAS :Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.
Formule :C40H52O4Degré de pureté :95.1% - 99.79%Couleur et forme :Needles From Acetone/Light Petroleum SolidMasse moléculaire :596.84Agrimol B
CAS :1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb.Formule :C37H46O12Degré de pureté :99.06% - ≥95%Couleur et forme :SolidMasse moléculaire :682.75(E/Z)-Elafibranor
CAS :GFT505 (Elafibranor) (Elafibranor) is a PPARα/δ agonist with EC50s of 45 and 175 nM, respectively.Formule :C22H24O4SDegré de pureté :98.36%Couleur et forme :SolidMasse moléculaire :384.49Ref: TM-T8699
2mg35,00€5mg52,00€10mg66,00€25mg104,00€50mg167,00€100mg259,00€200mg388,00€1mL*10mM (DMSO)54,00€Avicularin
CAS :Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.Formule :C20H18O11Degré de pureté :97.02% - 99.94%Couleur et forme :White PowderMasse moléculaire :434.35Ref: TM-T6S0117
1mg55,00€5mg92,00€10mg152,00€25mg268,00€50mg395,00€100mg583,00€200mg832,00€1mL*10mM (DMSO)105,00€Bilobetin
CAS :Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet.Formule :C31H20O10Degré de pureté :97% - 99.69%Couleur et forme :SolidMasse moléculaire :552.48Ref: TM-T4S2128
1mg44,00€2mg66,00€5mg137,00€10mg236,00€25mg403,00€50mg582,00€100mg800,00€1mL*10mM (DMSO)177,00€Choline Fenofibrate
CAS :Choline Fenofibrate (Trilipix) is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic
Formule :C22H28ClNO5Degré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :421.91Pirinixic Acid
CAS :Pirinixic Acid (NSC 310038) is a synthetic thiacetic acid derivative used in biomedical research, a peroxisome proliferator that activates specific PPAR.Formule :C14H14ClN3O2SDegré de pureté :98.27% - 99.92%Couleur et forme :SolidMasse moléculaire :323.8Ref: TM-T2269
1g350,00€10mg48,00€25mg64,00€50mg79,00€100mg105,00€200mg148,00€500mg236,00€1mL*10mM (DMSO)47,00€Adelmidrol
CAS :Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.Formule :C13H26N2O4Degré de pureté :99.35% - 99.73%Couleur et forme :SolidMasse moléculaire :274.36Rosiglitazone hydrochloride
CAS :Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.Formule :C18H19N3O3S·HClDegré de pureté :99.63% - 99.79%Couleur et forme :SolidMasse moléculaire :393.89GW1929
CAS :GW1929 is a potent PPAR-γ agonist (pKi: 8.84 for human PPAR-γ; pEC50s of 8.56 and 8.27 for human and murine PPAR-γ).
Formule :C30H29N3O4Degré de pureté :98.1% - 98.21%Couleur et forme :SolidMasse moléculaire :495.57GSK3787
CAS :GSK3787 is a specific and irreversible PPARδ inhibitor（pIC50= 6.6）.Formule :C15H12ClF3N2O3SDegré de pureté :98% - 99.56%Couleur et forme :SolidMasse moléculaire :392.78Ref: TM-T1941
5mg55,00€10mg87,00€25mg173,00€50mg309,00€100mg520,00€500mg1.111,00€1mL*10mM (DMSO)55,00€Bocidelpar
CAS :Bocidelpar is a modulator of PPARδ with an EC50 of 7.80 nM and improves mitochondrial biogenesis and function in Duchenne Muscular Dystrophy muscle cells.Formule :C25H27F3N2O3Degré de pureté :97.77%Couleur et forme :SolidMasse moléculaire :460.49Ref: TM-T39516
1mg114,00€5mg260,00€10mg389,00€25mg703,00€50mg1.054,00€100mg1.468,00€1mL*10mM (DMSO)264,00€
