Transférase
Les transférases sont une grande classe d'enzymes qui catalysent le transfert de groupes fonctionnels, tels que les groupes méthyle, glycosyle et phosphate, d'une molécule à une autre. Les inhibiteurs des transférases sont utilisés pour étudier un large éventail de processus biologiques, notamment la transduction du signal, le métabolisme et l'expression génique. Ces inhibiteurs sont des outils essentiels dans des domaines de recherche tels que le cancer, les maladies métaboliques et l'épigénétique, où la dysrégulation de l'activité des transférases est impliquée. Chez CymitQuimica, nous proposons une sélection complète d'inhibiteurs de transférases pour soutenir vos recherches en enzymologie, signalisation cellulaire et mécanismes de la maladie.
30 produits trouvés pour "Transférase"
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Cycloleucine
CAS :<p>Cycloleucine is an antagonist of NMDA receptor associated glycine receptor with a Ki of 600 μM.</p>Formule :C6H11NO2Degré de pureté :99.90%Couleur et forme :SolidMasse moléculaire :129.16Opicapone
CAS :<p>Opicapone (BIA 9-1067), a potent COMT inhibitor for Parkinson's studies, lowers cell ATP (IC50: 98 μM).</p>Formule :C15H10Cl2N4O6Degré de pureté :98.17% - 99.36%Couleur et forme :SolidMasse moléculaire :413.17Sinbaglustat
CAS :<p>Sinbaglustat (OGT2378), an oral N-alkyl iminosugar, inhibits GCS/GBA2 and treats lysosomal storage and neurodegenerative disorders.</p>Formule :C11H23NO4Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :233.3Histamine glutarimide
CAS :<p>Histamine glutarimide is a novel QPCT inhibitor that targets inflammatory processes like eosinophil migration, showing anti-asthmatic effects in animal models.</p>Formule :C10H13N3O2Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :207.23FUT8-IN-1
<p>FUT8-IN-1 (Compound 37) is an inhibitor of α-1,6-fucosyltransferase (FUT8), with a dissociation constant (KD) of 49 nM and an IC50 around 50 µM. In the presence of FUT8, FUT8-IN-1 forms a highly active naphthoquinone imine intermediate, thereby inhibiting FUT8's enzymatic activity.</p>Formule :C23H25ClN2OCouleur et forme :SolidMasse moléculaire :380.91β-1,4-GALT1-IN-1
<p>β-1,4-GALT1-IN-1 (Compound 6) is a β-1,4-GALT1 inhibitor with an IC50 value of 6.2 μM. It is applicable in studying various pathological conditions, including cancer, autoimmune diseases, and viral infections.</p>Formule :C29H23NO10Couleur et forme :SolidMasse moléculaire :545.494ST6 Sialyltransferase 5
<p>ST6Sialyltransferase5 (EC:2.4.3.3, ST6GALNAC5, SIAT7E, ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5) transfers sialic acid to N-acetylgalactosamine (GalNAc) residues. It may serve as a biomarker in cervical screening samples.</p>L-739750 2HCl
<p>L-739750 2HCl is a potent inhibitor of peptidomimetic farnesyltransferase, a novel pseudopeptide mimetic with potential anticancer activity.</p>Formule :C23H41Cl2N3O6S2Degré de pureté :98.69% - 99.16%Couleur et forme :SoildMasse moléculaire :590.62Tipifarnib
CAS :<p>Tipifarnib (IND 58359), a quinolinone, inhibits farnesyl transferase, blocks Ras activation, arrests cell growth, and curbs angiogenesis.</p>Formule :C27H22Cl2N4ODegré de pureté :97.1% - 99.22%Couleur et forme :Off-White To Pale Beige SolidMasse moléculaire :489.4Ibiglustat
CAS :<p>Ibiglustat (GZ402671) inhibits Glucosylceramide synthase, may treat Fabry disease by preventing GL-3 synthesis.</p>Formule :C20H24FN3O2SDegré de pureté :97.97% - 98.81%Couleur et forme :SolidMasse moléculaire :389.49Entacapone
CAS :<p>Entacapone (OR-611) is a selective and reversible inhibitor of catechol-O-methyltransferase (COMT).</p>Formule :C14H15N3O5Degré de pureté :98.80% - >99.99%Couleur et forme :Yellow Crystalline SolidMasse moléculaire :305.29Tipifarnib (S enantiomer)
CAS :<p>Tipifarnib S enantiomer ((S)-(-)-R-115777) is the S-enantiomer of Tipifarnib. Tipifarnib is a potent and specific farnesyltransferase inhibitor (IC50: 0.6 nM).</p>Formule :C27H22Cl2N4ODegré de pureté :99.05%Couleur et forme :SolidMasse moléculaire :489.4PD 128042
CAS :<p>PD 128042 (CI 976) is a potent orally active and selective ACAT inhibitor(IC50: 73 nM) and a potent lysophospholipid acyltransferase(LPAT) inhibitor.</p>Formule :C23H39NO4Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :393.56CP-609754
CAS :<p>CP-609754 shows selective inhibition of farnesyltransferase.</p>Formule :C29H22ClN3O2Degré de pureté :99.04% - 99.86%Couleur et forme :SolidMasse moléculaire :479.96Nitecapone
CAS :<p>Nitecapone is a reversible inhibitor of S-COMT (IC50 values of 300 nM in rat liver)</p>Formule :C12H11NO6Degré de pureté :98.39%Couleur et forme :SolidMasse moléculaire :265.22Ervogastat
CAS :<p>Ervogastat (PF-06865571) is a potent and well-tolerated diacylglycerol acyltransferase 2 inhibitor.</p>Formule :C21H21N5O4Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :407.423-O-Methyltolcapone
CAS :<p>3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone which is a potent COMT inhibitor.</p>Formule :C15H13NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :287.27AMP-Deoxynojirimycin
CAS :<p>AMP-Deoxynojirimycin (AMP-DNM) is a ceramide glucosyltransferase and GCase 2 inhibitor for the study of Parkinson's and diabetes.</p>Formule :C22H39NO5Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :397.55Lucerastat
CAS :<p>Lucerastat（NBDGJ） is an orally available inhibitor of GCS for Fabry disease by reducing harmful substrates.. GCS is a key enzyme in sphingolipid synthesiss.</p>Formule :C10H21NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :219.28P-3FAX-Neu5Ac
CAS :<p>P-3FAX-Neu5Ac is a sialic acid analog and a sialyltransferase inhibitor.</p>Formule :C22H30FNO14Degré de pureté :97.08%Couleur et forme :SolidMasse moléculaire :551.47Prenyl-IN-1
CAS :<p>Prenyl-IN-1 inhibits prenylation selectively, counters oxidative stress in Parkinson's.</p>Formule :C28H24ClN5O2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :497.98α-2,3-sialyltransferase-IN-1
CAS :<p>α-2,3-sialyltransferase-IN-1 is a noncompetitive inhibitor of α-2,3-sialyltransferase(IC50 of 6 μM).</p>Formule :C28H45NO6Degré de pureté :98% - 98%Couleur et forme :SolidMasse moléculaire :491.66Ibiglustat (L-Malic acid)
CAS :<p>Ibiglustat (L-Malic acid) (Ibiglustat L-Malic acid) is a selective, brain-penetrant, and allosteric inhibitor of glucosylceramide synthase.</p>Formule :C24H30FN3O7SDegré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :523.57OSMI-1
CAS :<p>OSMI-1: cell-permeable OGT inhibitor, blocks O-GlcNAcylation (IC50: 2.7 μM), no effect on other cell glycans.</p>Formule :C28H25N3O6S2Degré de pureté :96.79% - 99.39%Couleur et forme :SolidMasse moléculaire :563.64Miglustat hydrochloride
CAS :<p>Miglustat hydrochloride (N-Butyldeoxynojirimycin hydrochloride) is an inhibitor of glucosylceramide synthase and can be used for studies about Type I Gaucher</p>Formule :C10H22ClNO4Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :255.74FGTI-2734
CAS :<p>FGTI-2734, a dual FT/GGT-1 inhibitor (IC50: 250/520 nM), blocks KRAS membrane binding and curbs KRAS-driven pancreatic cancer.</p>Formule :C26H31FN6O2SDegré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :510.63BMS-214662 mesylate
CAS :<p>BMS-214662 mesylate is a potent and selective farnesyl transferase inhibitor with an IC50 of 1.35 nM. It exhibits antitumor activity and is applicable in cancer research.</p>Formule :C26H27N5O5S3Couleur et forme :SolidMasse moléculaire :585.718ICMT-IN-55
CAS :<p>ICMT-IN-55 (compound 31) acts as an ICMT inhibitor, exhibiting an IC50 value of 90 nM [1].</p>Formule :C22H26F3NO2Couleur et forme :SolidMasse moléculaire :393.44Glucosylceramide synthase-IN-4
CAS :<p>Glucosylceramide Synthase-IN-4 (compound 12) serves as a potent inhibitor of glucosylceramide synthase (GCS), exhibiting an IC50 of 6.8 nM. It demonstrates superior pharmacokinetic properties and robust stability in human hepatocytes. Additionally, this compound is noted for its effective CNS penetration and acceptable PXR selectivity [1].</p>Formule :C22H18F5N3O3Couleur et forme :SolidMasse moléculaire :467.39Darlifarnib
CAS :<p>Darlifarnib (Compound (S)-058) is an inhibitor of farnesyl transferase and geranylgeranyltransferase, with IC50 values of ≤ 10 nM and > 1000 nM, respectively. It exhibits high metabolic stability in human and mouse liver microsomes, with a half-life of over 100 minutes.</p>Formule :C29H20N6OCouleur et forme :SolidMasse moléculaire :468.509
