Déshydrogénase
Les déshydrogénases sont des enzymes impliquées dans les réactions d'oxydoréduction des voies métaboliques, jouant un rôle central dans la production d'énergie et la respiration cellulaire. Ces enzymes sont cruciales pour des processus tels que le cycle de l'acide citrique, la glycolyse et l'oxydation des acides gras. Les inhibiteurs de déshydrogénases sont des outils importants dans l'étude des maladies métaboliques, du cancer et du stress oxydatif. Chez CymitQuimica, nous proposons une sélection complète d'inhibiteurs de déshydrogénases pour soutenir vos recherches en métabolisme, biologie du cancer et biochimie.
267 produits trouvés pour "Déshydrogénase"
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LDH-IN-1
CAS :<p>LDH-IN-1 is a pyrazole-based human lactate dehydrogenase (LDH) inhibitor(IC50s of 32 and 27 nM for LDHA and LDHB, respectively).</p>Formule :C30H26N4O4S2Degré de pureté :99.6%Couleur et forme :SolidMasse moléculaire :570.68Mutant IDH1 inhibitor
CAS :<p>Mutant IDH1 inhibitor is an effective inhibitor of mutant IDH1 R132H (IC50: < 72 nM).</p>Formule :C25H34N6O3Degré de pureté :98.3%Couleur et forme :SolidMasse moléculaire :466.58DHODH-IN-11
CAS :<p>DHODH-IN-11 is a leflunomide derivative and weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03.</p>Formule :C15H11N3O2Degré de pureté :98.14%Couleur et forme :SolidMasse moléculaire :265.27CVT-10216
CAS :<p>CVT-10216 inhibits ALDH2 (IC50: 29 nM) and ALDH-1 (IC50: 1.3 μM), reducing alcohol intake and anxiety in rats.</p>Formule :C24H19NO7SDegré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :465.48BAY-2402234
CAS :<p>BAY-2402234: a selective DHODH inhibitor targeting myeloid cancers with low-nanomolar potency.</p>Formule :C21H18ClF5N4O4Degré de pureté :98.9%Couleur et forme :SolidMasse moléculaire :520.84Olutasidenib
CAS :<p>Olutasidenib (FT-2102), an IDH1 inhibitor (IC50: 21.2/114 nM), is studied for treating AML/MDS and can cross the blood-brain barrier.</p>Formule :C18H15ClN4O2Degré de pureté :98.57%Couleur et forme :SolidMasse moléculaire :354.79SCD1 inhibitor-4
CAS :<p>SCD1 inhibitor-4 is stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes.</p>Formule :C17H16F3N5ODegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :363.344-Diethylaminobenzaldehyde
CAS :<p>4-Diethylaminobenzaldehyde: reversible ALDH1 inhibitor (Ki: 4 nM), potent anti-androgen (IC50: 1.71μM).</p>Formule :C11H15NODegré de pureté :99.6%Couleur et forme :Brown-Black CrystalsMasse moléculaire :177.24ML390
CAS :<p>ML390 exerts its potent differentiation effect on multiple leukemia models.</p>Formule :C21H21F3N2O3Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :406.4CAY10566
CAS :<p>CAY10566 is a potent SCD1 inhibitor, orally bioavailable, with IC50s: HepG2 cells, 7.9nM; mouse, 4.5nM; human, 26nM.</p>Formule :C18H17ClFN5O2Degré de pureté :99.5% - 99.54%Couleur et forme :SolidMasse moléculaire :389.81GSK2837808A
CAS :<p>GSK2837808A is a potent and selective inhibitor of lactate dehydrogenase A (LDHA) (IC50s: 1.9 and 14 nM for LDHA and LDHB, respectively).</p>Formule :C31H25F2N5O7SDegré de pureté :99.78% - 99.78%Couleur et forme :SolidMasse moléculaire :649.62MF-438
CAS :<p>MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1).</p>Formule :C19H18F3N5OSDegré de pureté :98.98% - 99.50%Couleur et forme :SolidMasse moléculaire :421.44Mycophenolic acid
CAS :<p>Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.</p>Formule :C17H20O6Degré de pureté :98.79% - 99.77%Couleur et forme :SolidMasse moléculaire :320.34NCT-502
CAS :<p>NCT-502 (N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide) is a human phosphoglycerate dehydrogenase inhibitor,</p>Formule :C18H20F3N5SDegré de pureté :99.60%Couleur et forme :SolidMasse moléculaire :395.45Trilostane
CAS :<p>Trilostane (Win 24540) is a synthetic derivative of androstane with adrenocortical suppressive properties.</p>Formule :C20H27NO3Degré de pureté :99.46% - >99.99%Couleur et forme :Tan CrystalsMasse moléculaire :329.43CBR-5884
CAS :<p>CBR-5884: active PHGDH inhibitor, IC50=33μM, disrupts serine synthesis, selectively targets high-serine cancers.</p>Formule :C14H12N2O4S2Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :336.39RS 61443
CAS :<p>RS 61443 (Mycophenolate mofetil) is an immunosuppressant, a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH)</p>Formule :C23H31NO7Degré de pureté :99.37% - 99.91%Couleur et forme :SolidMasse moléculaire :433.5Adrenosterone
CAS :<p>Adrenosterone (11-ketoandrostenedione) is a steroid hormone isolated from the adrenal cortex.</p>Formule :C19H24O3Degré de pureté :98.13% - 98.29%Couleur et forme :SolidMasse moléculaire :300.39KPLH1130
CAS :<p>KPLH1130, a PDK inhibitor, boosts glucose tolerance and reduces inflammation in high-fat diet mice.</p>Formule :C15H13N3O3Degré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :283.28LY 345899
CAS :<p>LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for</p>Formule :C20H21N7O7Degré de pureté :99.7%Couleur et forme :SolidMasse moléculaire :471.42PTC299
CAS :<p>PTC299 ((4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate) is an orally active inhibitor of VEGFA mRNA</p>Formule :C25H20Cl2N2O3Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :467.34IDH-305
CAS :<p>IDH-305: Oral, mutation-specific IDH1 inhibitor, 200x selective for R132 mutants; IC50: 27/28/6.14 nM for R132H/C/WT.</p>Formule :C23H22F4N6O2Degré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :490.45XEN723
CAS :<p>XEN723 is a potent thiazolylimidazolidinone Stearoyl-CoA Desaturase (SCD1) inhibitor(IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively).</p>Formule :C21H20FN5O2SDegré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :425.48Antiproliferative agent-13
CAS :<p>Antiproliferative agent-13 is a compound with antiproliferative activity.</p>Formule :C20H18N2O6Degré de pureté :99.723%Couleur et forme :SolidMasse moléculaire :382.37DSM705
CAS :<p>DSM705: Pyrrole-based, potent nanomolar Plasmodium DHODH inhibitor with strong antimalarial efficacy; spares mammalian DHODH.</p>Formule :C19H19F3N6OCouleur et forme :SolidMasse moléculaire :404.397Diethanolamine hydrochloride
CAS :<p>Diethanolamine hydrochloride is HSD17B4 (hydroxysteroid 17-beta dehydrogenase 4) and pregnane X receptor (PXR), p53 Estrogen receptor.</p>Formule :C4H12ClNO2Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :141.6DHODH-IN-16
CAS :<p>DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).</p>Formule :C24H25FN4O3Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :436.48WAY-311610
CAS :<p>WAY-311610 is an HSD11B1 inhibitor targeting 11β-HSD1 enzyme with 0.34 μM IC; used for neuropathic and inflammatory pain research.</p>Formule :C16H13F3N4O2Degré de pureté :98.01%Couleur et forme :SolidMasse moléculaire :350.3hDHODH-IN-8
CAS :<p>hDHODH-IN-8: potent hDHODH inhibitor, IC50 = 16 nM, antiproliferative, soluble, may research lymphoma.</p>Formule :C21H15F6N3O4Degré de pureté :98%Couleur et forme :SoildMasse moléculaire :487.3511β-HSD1 inibitor 19
CAS :<p>3-chloro-4-sulfonyl-Benzonitrile inhibits hHSD1/mHSD1, IC50: 16nM/10nM.</p>Formule :C19H16ClF4N3O2SDegré de pureté :99.58%Couleur et forme :SoildMasse moléculaire :461.86hDHODH-IN-12
<p>hDHODH-IN-12 is a potent inhibitor of dihydroorotate dehydrogenase (DHODH), exhibiting an inhibitory concentration (IC50) of 0.421 μM.</p>Formule :C22H15F3N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :440.37LDHA-IN-8
CAS :<p>LDHA-IN-8, an inhibitor, inhibits the proliferation of pancreatic and lung cancer cells, decreasing the intracellular lactate content and increasing ROS levels.</p>Formule :C15H14N4O2Degré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :282.3IGUANA-1
CAS :<p>IGUANA-1 is a highly efficient and selective ALDH1B1 inhibitor that inhibits the growth of colorectal cancer cells and colorectal cancer cell-derived organoids.</p>Formule :C27H26ClN3O4Degré de pureté :99.08%Couleur et forme :SolidMasse moléculaire :491.97DHODH-IN-23
CAS :<p>DHODH-IN-23 is a DHODH inhibitor with oral activity. DHODH-IN-23 is often used in cancer research.</p>Formule :C24H21ClFNO4Degré de pureté :99.7%Couleur et forme :SolidMasse moléculaire :441.88Nedosiran sodium
CAS :<p>Nedosiran sodium, a GalNAc-dsRNA conjugate, is engineered to suppress the synthesis of the hepatic lactate dehydrogenase (LDH) enzyme.</p>Couleur et forme :SolidMTHFD2-IN-3
<p>MTHFD2-IN-3 (compound 10), a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2), demonstrates significant efficacy in obstructing the activity</p>Formule :C22H19NO7SCouleur et forme :SolidMasse moléculaire :441.452,3-Dihydroxybenzaldehyde
CAS :<p>2,3-Dihydroxybenzaldehyde exhibits activity against NADH dehydrogenase (Km = 35 µM) and can be used in biochemical experiments and drug synthesis.</p>Formule :C7H6O3Couleur et forme :SolidMasse moléculaire :138.12Octanoyl Coenzyme A (sodium salt)
<p>Octanoyl Coenzyme A (sodium salt) inhibits citrate synthase and glutamate dehydrogenase with an IC50 of 0.4–1.6 mM.</p>Formule :C29H49N7NaO17P3SCouleur et forme :SolidMasse moléculaire :915.71PDK-IN-2
<p>PDK-IN-2 (Compound 1F), with an IC50 of 68 nM, is a potent PDK inhibitor that downregulates the expression of PDK1 and PDK4 in cells.</p>Formule :C17H23AsCl2N2O2S2Couleur et forme :SolidMasse moléculaire :497.3311β-HSD1 inibitor 17
CAS :<p>11β-HSD1 inibitor 17 is an inhibitor of 11β-hydroxysteroid dehydrogenase (11β-HSD1).</p>Formule :C22H20F3N3O2SDegré de pureté :99.26% - 99.72%Couleur et forme :SoildMasse moléculaire :447.4711β-HSD1-IN-11
CAS :<p>11β-HSd1-in-11 is a potent and competitive inhibitor of 11-β-hydroxysteroid dehydrogenase 1 (11β-HSD1) IN rats and humans with IC50 values of 0.34 μM and 0.13</p>Formule :C15H11F3O3SDegré de pureté :99.61%Couleur et forme :SoildMasse moléculaire :328.31MTHFD2-IN-4 sodium
<p>MTHFD2-IN-4 sodium, a potent inhibitor of MTHFD2 and a tricyclic coumarin derivative, is applicable in cancer research [1].</p>Formule :C26H21F6N2NaO5Couleur et forme :SolidMasse moléculaire :578.44MTHFD2-IN-4
<p>MTHFD2-IN-4, a tricyclic coumarin derivative, serves as a potent inhibitor of MTHFD2 and has applications in cancer research [1].</p>Formule :C26H21F6N2O5Couleur et forme :SolidMasse moléculaire :555.45IGUANA-1 free base
CAS :<p>IGUANA-1: selective ALDH1 B1 inhibitor, IC50=30 nM, hinders SW480 cell growth with IC50=2.46/0.39 μM in adherent/spheroid forms, for cancer research.</p>Formule :C26H24ClN3O2Couleur et forme :SolidMasse moléculaire :445.94PDK-IN-1
CAS :<p>PDK-IN-1, a PDK inhibitor, IC50: 0.03μM (PDK1), 0.1μM (HSP90), reduces tumor mass.</p>Formule :C20H16BrN7OCouleur et forme :SolidMasse moléculaire :450.29MTHFD2-IN-2
<p>MTHFD2-IN-2 (compound 13) serves as a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2) [1].</p>Formule :C22H18N4O5Couleur et forme :SolidMasse moléculaire :418.4Necroptosis-IN-3
CAS :<p>Necroptosis-IN-3 (Cyclohexanecarboxamide, N-(2-thienylmethyl)-) (Compound 69) is a Necroptosis inhibitor that inhibits TNF-α induced necroptosis.</p>Formule :C12H17NOSDegré de pureté :99.85%Couleur et forme :SoildMasse moléculaire :223.33CM121
CAS :<p>CM121, a reversible ALDH1A2 inhibitor, targets active site with IC50=0.54μM, Kd=1.1μM, using hydrophobic interactions.</p>Formule :C24H17FN4O3SCouleur et forme :SolidMasse moléculaire :460.4818β-Glycyrrhetyl-3-O-sulfate
CAS :<p>18β-Glycyrrhetyl-3-O-sulfate (Glycyrrhetic acid 3-O-(hydrogen sulfate)), a major metabolite of Glycyrrhetinic acid (GA), serves as a potent inhibitor of type 2</p>Formule :C30H46O7SCouleur et forme :SolidMasse moléculaire :550.75MTHFD2-IN-1
<p>MTHFD2-IN-1 (compound 12) is a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2) [1].</p>Formule :C24H21NO6Couleur et forme :SolidMasse moléculaire :419.43DHODH-IN-18
CAS :<p>DHODH-IN-18 is a human DHODH inhibitor ( IC 50 = 0.2 nM).</p>Formule :C21H16ClF5N6O4Couleur et forme :SolidMasse moléculaire :546.84SKI2852
CAS :<p>SKI2852 is an 11β-HSD1 inhibitor that improves metabolic syndrome in diabetic mouse models.</p>Formule :C27H34FN5O4SDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :543.6517β-HSD10-IN-1
CAS :<p>17β-HSD10-IN-1 is a 17β-hydroxysteroid dehydrogenase type 10 inhibitor with blood-brain permeability and potency for the study of Alzheimer's disease.</p>Formule :C16H13ClN4O3SDegré de pureté :98.47%Couleur et forme :SoildMasse moléculaire :376.82LDHA-IN-3
CAS :<p>LDHA-IN-3 is a potent selenobenzene-based LDHA inhibitor with a 145.2 nM IC50, useful in cancer research.</p>Formule :C13H9F3SeDegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :301.17TC HSD 21
CAS :<p>TC HSD 21 is a potent and highly selective inhibitor of 17β-hydroxysteroid dehydrogenase type 3 (IC50 = 14 nM).</p>Formule :C17H12BrNO3S2Degré de pureté :98.5%Couleur et forme :SolidMasse moléculaire :422.32Ascochlorin A
CAS :<p>Ascochlorin A, a compound with a dissociation constant (K D) of 3.29 μM, serves as a novel and potent human dihydroorotate dehydrogenase (hDHODH) inhibitor</p>Formule :C23H31ClO4Couleur et forme :SolidMasse moléculaire :406.95SW209049
CAS :<p>SW209049 is a stearoyl-CoA 9-desaturase inhibitor. SW209049 exhivits potent activity against H2122 cell with IC50 of 0.13uM.</p>Formule :C25H18N2O4SDegré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :442.49KOTX1
CAS :<p>KOTX1 is an orally active and selective inhibitor of ALDH1A3. In a diabetic mouse model, KOTX1 improves glucose tolerance, insulin secretion, and blood glucose levels.</p>Formule :C17H16FN3O2Couleur et forme :SolidMasse moléculaire :313.33hDHODH-IN-13
CAS :<p>hDHODH-IN-13 (compound w2), an inhibitor of human dihydroorotate dehydrogenase (hDHODH), exhibits an IC50 of 173.4 nM and has potential research applications in</p>Couleur et forme :SoildhDHODH-IN-16
<p>hDHODH-IN-16 (Compound 3t) is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an IC50 of 0.11 μM. It demonstrates very low cytotoxicity towards healthy HaCaT cells, with an IC50 value exceeding 200 μM.</p>Formule :C18H20N2O2Couleur et forme :SolidMasse moléculaire :296.36SCD1 inhibitor-3
CAS :<p>SCD1 inhibitor-3 (ML-270) is a highly effective and orally available compound that inhibits SCD1 with remarkable safety.</p>Formule :C19H16FN7O2Degré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :393.37BVT-2733 hydrochloride
CAS :<p>BVT-2733 hydrochloride is a potent, selective, and orally active non-steroidal 11β-HSD1 inhibitor. It exhibits stronger inhibition on mouse 11β-HSD1 enzyme (IC50=96 nM) compared to the human 11β-HSD1 enzyme (IC50=3341 nM). BVT-2733 hydrochloride shows potential for research in arthritis and obesity-related diseases.</p>Formule :C17H22Cl2N4O3S2Couleur et forme :SolidMasse moléculaire :465.42D-Lactate dehydrogenase
CAS :<p>D-LDH is an oxidoreductase turning D-lactate into pyruvate, using NAD+/NADP+; prevalent in bacteria and fungi, key for biochemical research.</p>Couleur et forme :SolidOsmanthuside H
CAS :<p>Osmanthuside H is a useful organic compound for research related to life sciences. The catalog number is T125796 and the CAS number is 149155-70-4.</p>Formule :C19H28O11Couleur et forme :SolidMasse moléculaire :432.422MCI-INI-3
CAS :<p>MCI-INI-3 is a selective competitive inhibitor of human ALDH1A3, with a Ki value of 0.55 μM for ALDH1A3 and 78.2 μM for ALDH1A1. It inhibits retinoic acid biosynthesis and can reduce the viability of glioblastoma cells GSC-83 and GSC-326.</p>Formule :C21H15N3O4Couleur et forme :SolidMasse moléculaire :373.36(Rac)-BMS-816336
<p>(Rac)-BMS-816336 is a racemic 11β-HSD1 inhibitor; IC50: 10 nM (human), 68 nM (mouse), metabolically stable.</p>Formule :C21H27NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :341.44DSM1465
<p>DSM1465 (Compound 82) is a potent and selective inhibitor of P. falciparum dihydroorotate dehydrogenase (PfDHODH) with an IC50 value of 15 nM. It inhibits P. falciparum 3D7 (Pf3D7) parasites with an EC50 value of 1.4 nM and demonstrates significant in vivo efficacy in humanized P. falciparum mouse models.</p>Formule :C17H12ClF6N5O2Couleur et forme :SolidMasse moléculaire :467.753BMS-770767
CAS :<p>BMS-770767 is a novel 11-betahydroxysteroid dehydrogenase type I (11ß-HSD1) inhibitor.</p>Formule :C19H18ClN3O2Couleur et forme :SolidMasse moléculaire :355.82Crelosidenib
CAS :<p>Crelosidenib is a potent and selective mutant IDH inhibitor for IDH1 R132H, IDH1 R132C, IDH2 R140Q, and IDH2 R172K mutases.</p>Formule :C28H36N6O3Degré de pureté :98.54%Couleur et forme :SolidMasse moléculaire :504.62ALDH1A2-IN-1
CAS :<p>ALDH1A2-IN-1 is a reversible active-site-directed ALDH1A2 inhibitor preventing spermatogenesis, useful in male contraceptive research.</p>Formule :C21H26N4O4SDegré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :430.52ALDH3A1-IN-1
CAS :<p>ALDH3A1-IN-1 (Compound 18) is a potent inhibitor of ALDH3A1 with IC50 of 1.61 μM, outperforms DEAB in prostate cancer cells.</p>Formule :C13H18N2O3Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :250.29Aldehyde dehydrogenase (NAD(P))
CAS :<p>ALDH catalyzes oxidation of aldehydes to acids, reducing NAD(P) to NAD(P)H, helping alleviate aldehyde stress.</p>Couleur et forme :SolidABT-384
CAS :<p>ABT-384 is a high-affinity, selective 11β-HSD1 inhibitor capable of suppressing hepatic and central nervous system HSD-1 activity for depressive disorder.</p>Formule :C25H34F3N5O2Degré de pureté :99.863%Couleur et forme :SolidMasse moléculaire :493.58ALDH1A3-IN-1
CAS :<p>ALDH1A3-IN-1 (Compound 14) is a potent inhibitor of ALDH1A3 which can be used in prostate cancer research (IC50 = 0.63 μM; Ki = 0.46 μM) [1].</p>Formule :C13H18BrNOCouleur et forme :SolidMasse moléculaire :284.192-Bromoacetamide
CAS :<p>2-Bromoacetamide (α-Bromoacetamide) is a class of disinfection by-products that exhibit developmental toxicity in animals.</p>Formule :C2H4BrNODegré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :137.96DSM265
CAS :<p>DSM265 (PfSPZ) is a dihydroorotic acid dehydrogenase inhibitor with antimalarial activity.DSM265 can be used for the treatment of malaria infections.</p>Formule :C14H12F7N5SDegré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :415.334-Isopropoxybenzaldehyde
CAS :<p>ALDH1A3-IN-3 inhibits ALDH1A3 (IC50: 0.26 μM), acts on ALDH3A1, and is used in prostate cancer research.</p>Formule :C10H12O2Degré de pureté :99.00%Couleur et forme :SolidMasse moléculaire :164.2DSM502
CAS :<p>DSM502 DSM502 is a dihydroorotic acid dehydrogenase (DHODH) inhibitor with antimalarial activity that inhibits Plasmodium DHODH and can be used as a lead for antimalarial compounds.</p>Formule :C16H16F3N3ODegré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :323.31Ketogestin
CAS :<p>Ketogestin is a progestational steroid and an inhibitor of enzyme 11β-hydroxysteroid dehydrogenase, and a weak negative modulator of GABAA receptors.</p>Formule :C21H28O3Degré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :328.45PKUMDL-WQ-2201
CAS :<p>PKUMDL-WQ-2201 is a selective allosteric inhibitor of phosphoglycerate dehydrogenase (PHGDH) with Anti-tumor Activity, it binds to site II.</p>Formule :C15H14ClN3O3SCouleur et forme :SolidMasse moléculaire :351.81Perfluorooctanoic acid
CAS :<p>Perfluorooctanoic acid (PFOA) (PFOA) is a persistent and widespread industry-made chemical.</p>Formule :C8HF15O2Degré de pureté :99.70%Couleur et forme :White To Off-White Powder OthersolidMasse moléculaire :414.07Nitrofurazone
CAS :<p>Nitrofurazone (Furacilin) is a topical anti-infective agent effective against gram-negative and gram-positive bacteria.</p>Formule :C6H6N4O4Degré de pureté :99.87%Couleur et forme :Pale Yellow Needles Solution) 6 0 - 6 5 Alkaline Solutions Are Dark Orange (Ntp 1992)Masse moléculaire :198.14DS-1001b
CAS :<p>DS-1001b is an inhibitor of mutant IDH-1 (Isocitrate Dehydrogenase-1)</p>Formule :C29H29Cl3FN3O4Degré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :608.92Dihydrouracil
CAS :<p>5,6-Dihydrouracil (5,6-Dihydrouracil) is an intermediate breakdown product of uracil.</p>Formule :C4H6N2O2Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :114.1AZD7545
CAS :<p>AZD7545 is a potent PDHK inhibitor.</p>Formule :C19H18ClF3N2O5SDegré de pureté :99.12% - 99.96%Couleur et forme :SolidMasse moléculaire :478.87BI-187004
CAS :<p>BI-187004 is an 11β-hydroxysteroid dehydrogenase 1 inhibitor.</p>Formule :C21H18N4ODegré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :342.39PfDHODH-IN-2
CAS :<p>PfDHODH-IN-2: powerful antimalarial, blocks PfDHODH (IC50: 1.11 μM), for malaria research.</p>Formule :C13H12ClNO3SDegré de pureté :98.9%Couleur et forme :SolidMasse moléculaire :297.76AGI-6780
CAS :<p>AGI-6780 is a potent and selective inhibitor of IDH2 R140Q mutant.</p>Formule :C21H18F3N3O3S2Degré de pureté :98.19% - 99.7%Couleur et forme :SolidMasse moléculaire :481.51Nitrofen
CAS :<p>Nitrofen is a selective contact herbicide. Nitrofen is a protoporphyrinogen oxidase and retinal dehydrogenase inhibitor.</p>Formule :C12H7Cl2NO3Degré de pureté :99.92%Couleur et forme :Less Crystals Or Black Solid Used As A Pre- Or Post-Emergence HerbicideMasse moléculaire :284.09LDHA-IN-4
CAS :<p>LDHA-IN-4 (AZ33) is an LDHA inhibitor. Binding affinity to 6-His-tagged human LDHA expressed in E.coli BL21 (DE3) by SPR analysis with an active value of 93 nM.</p>Formule :C25H27N3O6SDegré de pureté :98.17% - 99.68%Couleur et forme :SolidMasse moléculaire :497.56BVT 2733
CAS :<p>BVT 2733 is a new, non-steroidal, isoform-specific inhibitor of 11β-HSD1.</p>Formule :C17H21ClN4O3S2Degré de pureté :98% - 99.64%Couleur et forme :SolidMasse moléculaire :428.96PfDHODH-IN-1
CAS :<p>PfDHODH-IN-1 is an inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase(PfDHODH) which catalyzes the rate-limiting step for DNA and RNA biosynthesis.</p>Formule :C14H11F3N2O2Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :296.24AKR1C3-IN-1
CAS :<p>AKR1C3-IN-1 is a potent and selective inhibitor of AKR1C3(IC50 of 13 nM).</p>Formule :C16H15NO4SDegré de pureté :98.02%Couleur et forme :SolidMasse moléculaire :317.36AKR1C3-IN-4
CAS :<p>AKR1C3-IN-4: potent, selective AKR1C3 inhibitor, IC50 = 0.56 μM, potential for CRPC research.</p>Formule :C14H10F3NO2Degré de pureté :98.59%Couleur et forme :SolidMasse moléculaire :281.23BMS-823778 hydrochloride
CAS :<p>BMS-823778 hydrochloride is a potent, selective, and orally active inhibitor of 11β-HSD1 (11β-Hydroxysteroid Dehydrogenase Type 1), demonstrating an IC50 (half</p>Formule :C18H19Cl2N3OCouleur et forme :SolidMasse moléculaire :364.27G6PDi-1
CAS :<p>G6PDi-1 is an effective G6PD inhibitor. It depletes NADPH and decreases inflammatory cytokine production.</p>Formule :C14H12N4OSDegré de pureté :98.69%Couleur et forme :SolidMasse moléculaire :284.34R162
CAS :<p>R162 is an effective glutamate dehydrogenase 1 (GDH1) inhibitor.</p>Formule :C17H12O3Degré de pureté :96.21% - 98.15%Couleur et forme :SolidMasse moléculaire :264.28(E/Z)-Teriflunomide
CAS :<p>(E/Z)-Teriflunomide (Aubagio), a orally-available Pyrimidine Synthesis Inhibitor, is used to treat relapsing multiple sclerosis.</p>Formule :C12H9F3N2O2Degré de pureté :99.49% - 99.76%Couleur et forme :White SolidMasse moléculaire :270.21Brequinar
CAS :<p>Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.</p>Formule :C23H15F2NO2Degré de pureté :99.1% - 99.57%Couleur et forme :SolidMasse moléculaire :375.37PHGDH-inactive
CAS :<p>PHGDH inactive is inactive against PHGDH and serves as a negative control for NCT-502 and NCT-503 [1].</p>Formule :C17H21N5SDegré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :327.45Carbenoxolone disodium
CAS :<p>Carbenoxolone disodium treats stomach ulcers; derived from licorice, often has antidiuretic effects, low toxicity.</p>Formule :C34H48Na2O7Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :614.72MK-8245
CAS :<p>MK-8245 is a liver-targeting SCD inhibitor for human SCD1 (IC50: 1 nM) and for rat/mouse SCD1 (IC50: 3 nM), with anti-diabetic and anti-dyslipidemic function.</p>Formule :C17H16BrFN6O4Degré de pureté :97.58% - 99%Couleur et forme :SolidMasse moléculaire :467.25NCT-501 hydrochloride
CAS :<p>NCT-501 hydrochloride: potent, selective ALDH1A1 inhibitor based on theophylline; IC50 of 40 nM; highly discriminant against other ALDHs.</p>Formule :C21H33ClN6O3Couleur et forme :SolidMasse moléculaire :452.98Vidofludimus hemicalcium
CAS :Vidofludimus hemicalcium: oral DHODH inhibitor, FXR modulator, for autoimmune and fatty liver research.Formule :C20H18FNO4CaCouleur et forme :SolidMasse moléculaire :375.4AG-636
CAS :<p>AG-636 is a potent, reversible, selective and orally active DHODH inhibitor(IC50 of 17 nM). It has strong anticancer effects.</p>Formule :C21H17N3O2Degré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :343.38Sodium dichloroacetate
CAS :<p>Sodium dichloroacetate (BCA) inhibits PDK (IC50: 183 μM PDK2, 80 μM PDK4), triggers cancer cell apoptosis, and impedes tumor growth.</p>Formule :C2HCl2NaO2Degré de pureté :99.32% - 99.87%Couleur et forme :White PowderMasse moléculaire :150.92A939572
CAS :<p>A939572 is stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50 values of <4 nM for mSCD1 and 37 nM for hSCD1.</p>Formule :C20H22ClN3O3Degré de pureté :99.96% - ≥95%Couleur et forme :SolidMasse moléculaire :387.86Proguanil hydrochloride
CAS :<p>Proguanil hydrochloride, a biguanide, metabolizes into cycloguanil, an anti-malaria agent that inhibits plasmodium's DNA and protein synthesis.</p>Formule :C11H17Cl2N5Degré de pureté :98.34% - 98.39%Couleur et forme :SolidMasse moléculaire :290.19Ivosidenib
CAS :<p>Ivosidenib (AG-120) is an oral IDH1 inhibitor targeting mutated IDH1 to reduce 2-hydroxyglutarate and hinder tumor growth.</p>Formule :C28H22ClF3N6O3Degré de pureté :98.71% - 99.98%Couleur et forme :SolidMasse moléculaire :582.96Tiazofurin
CAS :<p>Tiazofurin, a synthetic nucleoside, has anti-cancer effects and inhibits IMPDH as TAD after metabolism.</p>Formule :C9H12N2O5SDegré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :260.27Galloflavin
CAS :<p>Galloflavin is a lactate dehydrogenase inhibitor. Galloflavin inhibits both human LDH isoforms (type A and type B).Cost-effective and quality-assured.</p>Formule :C12H6O8Degré de pureté :96.24% - 97.47%Couleur et forme :SolidMasse moléculaire :278.17NCT-505
CAS :<p>NCT-505 is a potent and selective inhibitor of aldehyde dehydrogenase (ALDH1A1, IC50 = 7 nM) and a weak inhibitor of hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 with</p>Formule :C27H28FN5O3SDegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :521.61VER-246608
CAS :<p>VER-246608 inhibits PDK (IC50: 35-91 nM), boosts PDC, reduces glycolysis, causes cancer cell cytostasis, and enhances doxorubicin effects.</p>Formule :C28H23ClF2N4O4Degré de pureté :98.5%Couleur et forme :SolidMasse moléculaire :552.96Mutant IDH1-IN-1
CAS :<p>Mutant IDH1-IN-1 is a potent mutant IDH1 R132 h inhibitor with IC50 < 0.1 uM.</p>Formule :C30H31FN4O2Degré de pureté :99.49% - >99.99%Couleur et forme :SolidMasse moléculaire :498.59NCT-503
CAS :<p>NCT-503 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor with no activity against other dehydrogenases. NCT-503 has antitumor activity. Cost-effective and quality-assured.</p>Formule :C20H23F3N4SDegré de pureté :98.91% - 99.84%Couleur et forme :SolidMasse moléculaire :408.48L-Allylglycine
CAS :<p>L-Allylglycine is a potent inhibitor of the synthetic enzyme for GABA, glutamic acid decarboxylase.</p>Formule :C5H9NO2Degré de pureté :≥98%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :115.13CM10
CAS :<p>CM10 is an aldehyde dehydrogenase 1A family(ALDH1A) inhibitor.</p>Formule :C20H23N3ODegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :321.42NCT-501
CAS :<p>NCT-501 is a potent and selective inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1) with IC50 of 40 nM.</p>Formule :C21H32N6O3Degré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :416.52AGI-5198
CAS :<p>AGI-5198 (IDH-C35) is a highly effective and specific inhibitor of IDH1 R132H/R132C mutants (IC50: 0.07/0.16 μM).</p>Formule :C27H31FN4O2Degré de pureté :97.37% - 99.23%Couleur et forme :SolidMasse moléculaire :462.56Nifurtimox
CAS :<p>Nifurtimox (BAY-A-2502) is an antiprotozoal agent (IC50s = 9.91, 12.28, and 10.44 μM against Taluahuén, LQ, and Brener strains of T.</p>Formule :C10H13N3O5SDegré de pureté :99.87% - 99.89%Couleur et forme :SolidMasse moléculaire :287.29BAY-1436032
CAS :<p>BAY-1436032 is a novel, selective and orally available inhibitor of pan-mutant isocitrate dehydrogenase 1 (IDH1).</p>Formule :C26H30F3N3O3Degré de pureté :99.65% - 99.71%Couleur et forme :SolidMasse moléculaire :489.53WIN 18446
CAS :<p>inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2)</p>Formule :C12H20Cl4N2O2Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :366.11Brequinar sodium
CAS :<p>Bipenquinate is a potent and selective inhibitor of dihydroorotate dehydrogenase (DHODH) with IC50 of 20 nM, blocking de novo pyrimidine biosynthesis.</p>Formule :C23H14F2NNaO2Degré de pureté :98.16%Couleur et forme :SolidMasse moléculaire :397.36Fomepizole
CAS :<p>Fomepizole (4-Methylpyrazole), a competitive inhibitor of alcohol dehydrogenase, is used as an antidote in methanol or ethylene glycol poisoning.</p>Formule :C4H6N2Degré de pureté :98.1% - 99.94%Couleur et forme :Yellow <13°C Solid >13°C LiquidMasse moléculaire :82.1Imidazole-5-propionic acid
CAS :<p>Imidazole-5-propionic acid (Imidazolylpropionic acid) is a product of histidine metabolism and may involve oxidation or transamination.</p>Formule :C6H8N2O2Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :140.14AG-120 (racemic)
CAS :<p>AG-120 (racemic) is an oral IDH1 inhibitor with potential anti-cancer effects.</p>Formule :C28H22ClF3N6O3Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :582.96Vidofludimus
CAS :<p>Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).</p>Formule :C20H18FNO4Degré de pureté :98.33% - 99.58%Couleur et forme :SolidMasse moléculaire :355.36BVT-14225
CAS :<p>BVT-14225 is a selective 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor (IC50=52 nM).</p>Formule :C16H20ClN3O3S2Degré de pureté :97.78%Couleur et forme :SolidMasse moléculaire :401.93(R)-GNE-140
CAS :<p>(R)-GNE-140 (GNE-140) is an effective LDHA/LDHB inhibitor (IC50s: 3/5 nM) and is 18-fold more potent than S enantiomer.</p>Formule :C25H23ClN2O3S2Degré de pureté :98.25% - 98.91%Couleur et forme :SolidMasse moléculaire :499.04Succinyl phosphonate trisodium salt
CAS :<p>Succinyl phosphonate trisodium salt is an inhibitor of α-ketoglutarate dehydrogenase (KGDHC)</p>Formule :C4H4Na3O6PDegré de pureté :99.8% - ≥95%Couleur et forme :SolidMasse moléculaire :248.01SW033291
CAS :<p>SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues.</p>Formule :C21H20N2OS3Degré de pureté :97.26% - 99.02%Couleur et forme :SolidMasse moléculaire :412.593-Hydroxybenzaldehyde
CAS :<p>3-Hydroxybenzaldehyde is a compound useful in organic synthesis.</p>Formule :C7H6O2Degré de pureté :99.60%Couleur et forme :DrypowderMasse moléculaire :122.126PGD-IN-S3
CAS :<p>6PGD-IN-S3 (6PGD Inhibitor S3) is an inhibitor of 6-phosphogluconate dehydrogenase (6PGD).</p>Formule :C15H10O4Degré de pureté :99.12%Couleur et forme :SolidMasse moléculaire :254.24Enasidenib
CAS :<p>Enasidenib (AG-221) is an orally available inhibitor of specific mutant forms of the mitochondrial enzyme isocitrate dehydrogenase type 2 (IDH2), with potential</p>Formule :C19H17F6N7ODegré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :473.38Enasidenib mesylate
CAS :<p>Enasidenib mesylate (AG-221 mesylate) is a IDH2 inhibitor that promotes differentiation of leukemia myeloid cells for the treatment of acute myeloid leukemia.</p>Formule :C20H21F6N7O4SDegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :569.48DS44960156
CAS :<p>DS44960156 is an inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) that inhibits both MTHFD2 and MTHFD1 and can be used in cancer research.</p>Formule :C20H15NO5Degré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :349.34GSK1940029
CAS :<p>GSK1940029 (SCD inhibitor 1) is a stearoyl-coa desaturase (SCD) inhibitor.</p>Formule :C18H16Cl2N4O2Degré de pureté :99.48% - 99.49%Couleur et forme :SolidMasse moléculaire :391.25Triflupromazine
CAS :<p>Triflupromazine is a dopamine receptor D1/D2 antagonist and LHDA inhibitor that suppresses dopamine activity in (CNS)mental disorders, sedation, and antiemesis.</p>Formule :C18H19F3N2SCouleur et forme :SolidMasse moléculaire :352.42hDHODH-IN-2
CAS :<p>hDHODH-IN-2: Leflunomide metabolite analog, inhibits human dihydroorotate dehydrogenase, anti-inflammatory.</p>Formule :C19H16N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :304.349Nitrophenide
CAS :<p>Nitrophenide, a 3,3'-Dinitrodiphenyl disulfide, blocks M1PDH in the mannitol cycle, serving as an anticoccidial.</p>Formule :C12H8N2O4S2Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :308.33AGI-14100
CAS :<p>AGI-14100 is a novel and orally available mIDH1 inhibitor.AGI-14100 is used for the treatment of primary human myeloid leukemia.</p>Formule :C29H22ClF4N5O3Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :599.96Epostane
CAS :<p>Epostane is a 3β-hydroxysteroid dehydrogenase inhibitor that blocks the biosynthesis of progesterone and pregnenolone.Cost-effective and quality-assured.</p>Formule :C22H31NO3Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :357.49DHODH-IN-24
CAS :<p>DHODH-IN-24 (compound 16) serves as a powerful inhibitor of human dihydroorotate dehydrogenase (DHODH), exhibiting an IC50 value of 91 nM [1].</p>Formule :C26H26N4Couleur et forme :SolidMasse moléculaire :394.51IMB-XMA0038
CAS :<p>IMB-XMA0038 is a Mycobacterium tuberculosis aspartate semialdehyde dehydrogenase inhibitor with antimicrobial activity for use in tuberculosis research.</p>Formule :C11H10N4O6Degré de pureté :98.94% - 99.96%Couleur et forme :SolidMasse moléculaire :294.22BI-4924
CAS :<p>BI-4924 is a PHGDH inhibitor that disrupts serine biosynthesis by intracellular trapping and can be used to study metabolic disorders.</p>Formule :C21H20Cl2N2O6SDegré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :499.36NCT-506
CAS :<p>NCT-506 is an orally bioavailable inhibitors of aldehyde dehydrogenase 1A1 (ALDH1A1) (IC50 of 7 nM).</p>Formule :C25H23FN4O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :478.54SCH-451659
CAS :<p>SCH-451659 is an 17β-hydroxysteroid dehydrogenases (17β-HSDs) inhibitor.</p>Formule :C30H39Cl2N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :544.56BI-135585
CAS :<p>BI-135585 is an orally active, selective and potent inhibitor of human 11β-hydroxysteroid dehydrogenase-1 (HSD1) for the study of type 2 diabetes.</p>Formule :C28H32N2O4Degré de pureté :99.45% - 99.57%Couleur et forme :SolidMasse moléculaire :460.57CM026
CAS :<p>CM026 inhibits ALDH1A1 selectively, binds to its aldehyde pocket uncompetitively.</p>Formule :C22H30N6O4Couleur et forme :SolidMasse moléculaire :442.51ML387
CAS :<p>ML387 is an inhibitor of human NAD(+)- dependent 15- hydroxyprostaglandin dehydrogenase.</p>Formule :C20H21N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :335.4Oxycinchophen
CAS :<p>Oxycinchophen: Quinoline-based anti-rheumatic with P-selectin inhibition, DHOD blockade, and anti-inflammatory impacts on vascular muscle.</p>Formule :C16H11NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :265.26GW648495
CAS :<p>GW648495 is a PfDHODH inhibitor that shows greater than 4,000-fold selectivity for the malarial enzyme.</p>Formule :C16H13N5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :275.31BVT-116429
CAS :<p>BVT-116429 is an inhibitor of 11β-HSD1.</p>Formule :C13H12F4N2OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :320.31GA11
CAS :<p>GA11is an inhibitor of ALDH1. It also displays anti-GBM effects in vitro and in vivo.</p>Formule :C19H14N2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :270.33RS6212
CAS :<p>RS6212 is a specific lactate dehydrogenase (LDH) inhibitor (IC50=12.03 μ M）。 RS6212 shows strong anticancer activity in a variety of cancer cell lines.</p>Formule :C20H22N4O3SCouleur et forme :SolidMasse moléculaire :398.48RORγt/DHODH-IN-2
CAS :<p>RORγt/DHODH-IN-2 (compound 1) is a potent dual RORγt/DHODH inhibitor that can be used in the study of inflammatory bowel disease (IBD).</p>Formule :C25H30N4OSCouleur et forme :SolidMasse moléculaire :434.6UCK2 Inhibitor-2
CAS :<p>UCK2 Inhibitor-2 is a non-competitive inhibitor of uridine-cytidine kinase 2 (UCK2) with IC50=3.8 µM that inhibits UCK2-mediated nucleoside recycling in cells.</p>Formule :C28H23N3O4SDegré de pureté :98.76% - 99.25%Couleur et forme :SolidMasse moléculaire :497.57DHODH-IN-20
CAS :<p>Dhodh-in-20 (Compound 133), a potent DHODH inhibitor, may help study acute myeloid leukemia and inhibit tumor growth.</p>Formule :C24H25F4N3O3Couleur et forme :SolidMasse moléculaire :479.47hDHODH-IN-4
CAS :<p>hDHODH-IN-4, a potent DHODH inhibitor, has a pIC50 of 7.8 and blocks measles virus replication with a pMIC50 of 8.8.</p>Formule :C21H24N4O2Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :364.44ALDH1A1-IN-3
CAS :<p>ALDH1A1-IN-3 selectively inhibits ALDH1A1, enhances HepG2 glucose consumption for metabolic research.</p>Formule :C31H36F3N5O4Couleur et forme :SolidMasse moléculaire :599.64AZD8329
CAS :<p>AZD8329 is an 11β-HSD1 inhibitor that inhibits 11β-HSD2, 17β-HSD1, 17β-HSD3, and can be used to study allergic reactions in humans.</p>Formule :C25H31N3O3Degré de pureté :99.31%Couleur et forme :SolidMasse moléculaire :421.53KM04416
CAS :<p>KM04416 is a GPD2 inhibitor that inhibits LUAD progression by modulating immune cell infiltration.</p>Formule :C12H11NO3SDegré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :249.29ALDH1A1-IN-2
CAS :<p>ALDH1A1-IN-2 is an aldehyde dehydrogenase 1a1 inhibitor with anticancer activity.ALDH1A1-IN-2 may be used in the study of breast cancer, inflammation or obesity</p>Formule :C25H23ClN4O3SDegré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :494.99Laflunimus
CAS :<p>Laflunimus (HR325) is a DHODH inhibitor that inhibits immunoglobulin secretion in vitro and in vivo,by interfering with pyrimidine metabolism,neuralgia.</p>Formule :C15H13F3N2O2Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :310.27hDHODH-IN-9
CAS :<p>hDHODH-IN-9 is a potent hDHODH inhibitor, IC50=0.34 μM, toxic to MCF-7/A375 cells, promising for cancer research.</p>Formule :C21H21NO4Couleur et forme :SolidMasse moléculaire :351.4RV01
CAS :<p>RV01, a resveratrol-like quinoline, inhibits DNA damage, ALDH2 expression, and has antioxidant and anti-inflammatory properties.</p>Formule :C17H13NO2Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :263.29hDHODH-IN-3
CAS :<p>hDHODH-IN-3 is an inhibitor of human dihydroorotate dehydrogenase with a pMIC50 value of 8.6. hDHODH-IN-3 can inhibit measles virus replication.</p>Formule :C18H19BrN4O2Degré de pureté :99.871%Couleur et forme :SolidMasse moléculaire :403.27Genz-669178
CAS :<p>Genz-669178 is a wild-type inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH).</p>Formule :C17H14N4OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :322.38EN40
CAS :<p>EN40, as a covalent ligand, is a selective inhibitor of aldehyde dehydrogenase 3A1 (IC50: 2 uM).</p>Formule :C13H15NO2Couleur et forme :SolidMasse moléculaire :217.26DHODH-IN-13
CAS :<p>DHODH-IN-13 is an inhibitor of DHODH with IC50 of 4.3 μM for rat liver. DHODH-IN-13 can be used in studies about rheumatoid arthritis.</p>Formule :C10H6F3N3O3Degré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :273.17DHODH-IN-15
CAS :<p>DHODH-IN-15, a hydroxyfuran analogue of A771726, inhibits rat liver DHODH with an IC50 of 11 μM, and is used for rheumatoid arthritis.</p>Formule :C15H11N3O3Degré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :281.27DHODH-IN-17
CAS :<p>DHODH-IN-17 is a human DHODH inhibitor with an IC50 of 0.40 μM.</p>Formule :C12H9ClN2O2Degré de pureté :99.41% - 99.52%Couleur et forme :SolidMasse moléculaire :248.67DHODH-IN-1
CAS :<p>DHODH-IN-1 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 25 nM. DHODH-IN-1 is an inhibitor of the pyrimidine biosynthetic pathway.</p>Formule :C21H20F3N3O2Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :403.4hDHODH-IN-5
CAS :<p>hDHODH-IN-5 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH, IC50 = 0.91 μM).</p>Formule :C21H21F3N2O2Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :390.4p-Valerylphenol
CAS :<p>p-Valerylphenol (NSC-49186) can be used to synthesize acylphenoxyacetic acid compounds.</p>Formule :C11H14O2Degré de pureté :99.87%Couleur et forme :White To Light Beige PowderMasse moléculaire :178.23M77976
CAS :<p>M77976 inhibits PDK4 with an IC50 of 648 μM, targeting obesity and diabetes research.</p>Formule :C17H16N2O3Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :296.32Manitimus
CAS :<p>Manitimus is a potent immunosuppressive drug, and is an inhibitor of dehydroorotate dehydrogenase,.</p>Formule :C15H11F3N2O2Degré de pureté :99.75% - 99.75%Couleur et forme :SolidMasse moléculaire :308.26Metapramine
CAS :<p>Metapramine, a tricyclic antidepressant, blocks norepinephrine reuptake and is a low-affinity NMDA antagonist.</p>Formule :C16H18N2Degré de pureté :99.03% - 99.67%Couleur et forme :SolidMasse moléculaire :238.3311β-HSD1-IN-1
CAS :<p>11β-HSD1-IN-1 is an inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1, IC50: 52 nM), and used for the treatment of pain.</p>Formule :C18H14ClF4N3ODegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :399.77DHODH-IN-4
CAS :<p>DHODH-IN-4 inhibits human & Plasmodium DHODH; IC50: 4 μM (Pf), 0.18 μM (Hs). It has antimalarial properties.</p>Formule :C17H12Cl2N2O2Degré de pureté :99.34%Couleur et forme :SolidMasse moléculaire :347.2DHODH-IN-8
CAS :<p>DHODH-IN-8 is a DHODH inhibitor with antimalarial properties, IC50: 0.13 μM (human), 47.4 μM (P. falciparum); Ki: 0.016 μM (human), 5.6 μM (P. falciparum).</p>Formule :C17H13ClN2O2Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :312.7511β-HSD1-IN-12
CAS :<p>11β-HSD1-IN-12 is an 11β-HSD1 inhibitor.11β-HSD1-IN-12 is implicated in the conversion of glucocorticoids in vivo and can be used to study metabolic syndrome</p>Formule :C19H27ClN2O3SDegré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :398.95Nitrefazole
CAS :<p>Nitrefazole: a 4-nitroimidazole, inhibits ALDH enzyme crucial for alcohol metabolism, has potent, durable effects.</p>Formule :C10H8N4O4Couleur et forme :SolidMasse moléculaire :248.1911β-HSD1-IN-6
CAS :<p>11β-HSD1-IN-6 is a potent inhibitor of 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs).</p>Formule :C21H19ClN4OCouleur et forme :SolidMasse moléculaire :378.86CM39
CAS :<p>CM39 inhibits ALDH, linked to cancer stem-like cells & chemoresistance.</p>Formule :C19H15FN4OSCouleur et forme :SolidMasse moléculaire :366.41MEDS433
CAS :<p>MEDS433 inhibits dihydroorotate dehydrogenase (IC50 1.2 nM) and blocks replication of hCoV-OC43, hCoV-229E, SARS-CoV-2 at nanomolar levels.</p>Formule :C20H11F4N3O2Couleur et forme :SolidMasse moléculaire :401.31hDHODH-IN-11
CAS :<p>hDHODH-IN-11: potent hDHODH inhibitor, IC50 7.2 nM, low cytotoxicity, for AML research.</p>Formule :C24H23N3O3Couleur et forme :SolidMasse moléculaire :401.46DHODH-IN-12
CAS :<p>DHODH-IN-12 is a leflunomide derivative and a weak dihydrorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.07.</p>Formule :C10H9N3O2Degré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :203.2AMG-221
CAS :<p>AMG-221: potent 11β-HSD1 inhibitor, lowers glucose & insulin, reduces obesity in mice.</p>Formule :C14H22N2OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :266.411β-HSD1-IN-10
CAS :<p>11β-HSD1-IN-10, a potent inhibitor of 11β-HSD1 with an IC50 value of 1.8 µM for humans, is suitable for research into obesity, hyperglycemia, and cognitive</p>Formule :C16H10F3NO2Couleur et forme :SolidMasse moléculaire :305.25673-A
CAS :<p>673-A inhibits ALDH1A, depletes ovarian CSCs, induces necroptosis, and reverses chemo resistance.</p>Formule :C15H13NOCouleur et forme :SolidMasse moléculaire :223.27DHODH-IN-19
CAS :<p>DHODH-IN-19, a strong DHODH blocker, may help treat cancer and inflammation. (Patent WO2021238881A1)</p>Formule :C22H18ClF6N3O3Couleur et forme :SolidMasse moléculaire :521.84ASP3662
CAS :<p>ASP3662/SPI-62: Potent, selective CNS-penetrable 11β-HSD1 inhibitor; potential neuropathic pain treatment.</p>Formule :C19H16ClF3N4O2Couleur et forme :SolidMasse moléculaire :424.8TM-1
CAS :<p>TM-1: PDHK inhibitor, IC50 - PDHK1: 2.97μM, PDHK2: 5.2μM, prevents PDHC phosphorylation, inhibits cancer cell growth.</p>Formule :C26H32N2O6Couleur et forme :SolidMasse moléculaire :468.54DHODH-IN-3
CAS :<p>DHODH-IN-3: Human DHODH inhibitor with IC50 of 261 nM, Kiapp 32 nM, potential anti-malaria drug.</p>Formule :C17H13ClN2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :312.75ALDH3A1-IN-2
CAS :<p>ALDH3A1-IN-2 is a potent inhibitor targeting ALDH3A1 (IC50=1.29µM), potentially useful in cancer research.</p>Formule :C11H14N2O3Couleur et forme :SolidMasse moléculaire :222.2411β-HSD1-IN-9
CAS :<p>11β-HSD1-IN-9 is a potent inhibitor of 11β-HSD1, displaying IC50 values of 0.48 µM for human and 1.3 µM for murine variants, respectively.</p>Formule :C13H9F3N2OCouleur et forme :SolidMasse moléculaire :266.22DHODH-IN-21
CAS :<p>DHODH-IN-21, orally active DHODH blocker with 1.1 nM IC50, shows anticancer activity, potential for AML research.</p>Formule :C20H19ClF4N6O4Couleur et forme :SolidMasse moléculaire :518.85BRD9185
CAS :<p>BRD9185 is an inhibitor of Dihydroorotate dehydrogenase (DHODH) with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro.</p>Formule :C23H21F6N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :485.42P1788
CAS :<p>P1788 is a dihydroorotate dehydrogenase (DHODH) inhibitor that can induce DNA damage [1].</p>Formule :C15H17NO3Couleur et forme :SolidMasse moléculaire :259.3
