Déshydrogénase
Les déshydrogénases sont des enzymes impliquées dans les réactions d'oxydoréduction des voies métaboliques, jouant un rôle central dans la production d'énergie et la respiration cellulaire. Ces enzymes sont cruciales pour des processus tels que le cycle de l'acide citrique, la glycolyse et l'oxydation des acides gras. Les inhibiteurs de déshydrogénases sont des outils importants dans l'étude des maladies métaboliques, du cancer et du stress oxydatif. Chez CymitQuimica, nous proposons une sélection complète d'inhibiteurs de déshydrogénases pour soutenir vos recherches en métabolisme, biologie du cancer et biochimie.
318 produits trouvés pour "Déshydrogénase".
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LY 345899
CAS :LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM forFormule :C20H21N7O7Degré de pureté :99.7%Couleur et forme :SolidMasse moléculaire :471.42Ref: TM-T15827
1mg46,00€5mg152,00€1mL*10mM (DMSO)157,00€10mg224,00€25mg371,00€50mg522,00€100mg713,00€200mg982,00€Trilostane
CAS :Trilostane (Win 24540) is a synthetic derivative of androstane with adrenocortical suppressive properties.Formule :C20H27NO3Degré de pureté :99.46% - >99.99%Couleur et forme :Tan CrystalsMasse moléculaire :329.43CAY10566
CAS :CAY10566 is a potent SCD1 inhibitor, orally bioavailable, with IC50s: HepG2 cells, 7.9nM; mouse, 4.5nM; human, 26nM.Formule :C18H17ClFN5O2Degré de pureté :99.54% - 99.75%Couleur et forme :SolidMasse moléculaire :389.81Ref: TM-T14878
1mg48,00€1mL*10mM (DMSO)112,00€5mg131,00€10mg195,00€25mg353,00€50mg505,00€100mg710,00€200mg954,00€KPLH1130
CAS :KPLH1130, a PDK inhibitor, boosts glucose tolerance and reduces inflammation in high-fat diet mice.Formule :C15H13N3O3Degré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :283.28Ref: TM-T11765
1mg79,00€1mL*10mM (DMSO)178,00€5mg205,00€10mg333,00€25mg560,00€50mg797,00€100mg1.071,00€500mg2.187,00€MTHFD2-IN-1
MTHFD2-IN-1 (compound 12) is a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2) [1].Formule :C24H21NO6Couleur et forme :SolidMasse moléculaire :419.4318β-Glycyrrhetyl-3-O-sulfate
CAS :18β-Glycyrrhetyl-3-O-sulfate (Glycyrrhetic acid 3-O-(hydrogen sulfate)), a major metabolite of Glycyrrhetinic acid (GA), serves as a potent inhibitor of type 2Formule :C30H46O7SCouleur et forme :SolidMasse moléculaire :550.75Ascochlorin A
CAS :Ascochlorin A, a compound with a dissociation constant (K D) of 3.29 μM, serves as a novel and potent human dihydroorotate dehydrogenase (hDHODH) inhibitorFormule :C23H31ClO4Couleur et forme :SolidMasse moléculaire :406.95Necroptosis-IN-3
CAS :Necroptosis-IN-3 (Cyclohexanecarboxamide, N-(2-thienylmethyl)-) (Compound 69) is a Necroptosis inhibitor that inhibits TNF-α induced necroptosis.Formule :C12H17NOSDegré de pureté :99.85%Couleur et forme :SoildMasse moléculaire :223.3311β-HSD1 inibitor 17
CAS :11β-HSD1 inibitor 17 is an inhibitor of 11β-hydroxysteroid dehydrogenase (11β-HSD1).Formule :C22H20F3N3O2SDegré de pureté :99.26% - 99.72%Couleur et forme :SolidMasse moléculaire :447.47DHODH-IN-18
CAS :DHODH-IN-18 is a human DHODH inhibitor ( IC 50 = 0.2 nM).Formule :C21H16ClF5N6O4Couleur et forme :SolidMasse moléculaire :546.84PDK-IN-3
PDK-IN-3 (compound 1) is a potent pan-inhibitor of PDK, with IC50 values of 109.3 nM, 135.8 nM, 458.7 nM, and 8.67 μM for PDK 1-4, respectively. Additionally, PDK-IN-3 induces proliferation and apoptosis in A549 cells.Formule :C16H19ClN2O5S2Couleur et forme :SolidMasse moléculaire :418.0423911β-HSD1-IN-11
CAS :11β-HSd1-in-11 is a potent and competitive inhibitor of 11-β-hydroxysteroid dehydrogenase 1 (11β-HSD1) IN rats and humans with IC50 values of 0.34 μM and 0.13Formule :C15H11F3O3SDegré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :328.31Ref: TM-T60149
1mg109,00€1mL*10mM (DMSO)239,00€5mg241,00€10mg355,00€25mg532,00€50mg745,00€100mg1.018,00€500mg2.043,00€SCD1 inhibitor-3
CAS :SCD1 inhibitor-3 (ML-270) is a highly effective and orally available compound that inhibits SCD1 with remarkable safety.Formule :C19H16FN7O2Degré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :393.37Ref: TM-T38683
1mg87,00€5mg177,00€1mL*10mM (DMSO)195,00€10mg281,00€25mg480,00€50mg692,00€100mg973,00€MTHFD2-IN-2
MTHFD2-IN-2 (compound 13) serves as a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2) [1].Formule :C22H18N4O5Couleur et forme :SolidMasse moléculaire :418.4MTHFD2-IN-4 sodium
MTHFD2-IN-4 sodium, a potent inhibitor of MTHFD2 and a tricyclic coumarin derivative, is applicable in cancer research [1].Formule :C26H21F6N2NaO5Couleur et forme :SolidMasse moléculaire :578.44PHGDH-IN-5
CAS :Compound B12 (PHGDH-IN-5) acts as a covalent inhibitor of PHGDH, demonstrating an IC50 value of 0.29 μM. It has been shown to inhibit the proliferation of cancer cell lines that overexpress PHGDH and reduce the production of glucose-derived serine in MDA-MB-468 cells [1].Formule :C8H5NO4SCouleur et forme :SolidMasse moléculaire :211.20MTHFD2-IN-3
MTHFD2-IN-3 (compound 10), a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2), demonstrates significant efficacy in obstructing the activityFormule :C22H19NO7SCouleur et forme :SolidMasse moléculaire :441.45LDH-IN-3
LDH-IN-3 (compound E38) is an inhibitor of lactate dehydrogenase (LDH) and a potential protective agent against ischemic neuronal damage in the eyes and brain. It functions through the HO-1/SIRT1 pathway.Formule :C32H27NO5Couleur et forme :SolidMasse moléculaire :505.56Succinate dehydrogenase-IN-4
Succinate dehydrogenase-IN-4 (Compound 4b) is an inhibitor of succinate dehydrogenase with an IC50 value of 3.38 μM. It exhibits antifungal activity against Physalospora piricola and Colletotrichum orbiculare, with EC50 values of 16.33 μM and 18.06 μM, respectively.Formule :C20H21N3O2S2Couleur et forme :SolidMasse moléculaire :399.53hDHODH-IN-12
hDHODH-IN-12 is a potent inhibitor of dihydroorotate dehydrogenase (DHODH), exhibiting an inhibitory concentration (IC50) of 0.421 μM.Formule :C22H15F3N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :440.37
