Déshydrogénase
Les déshydrogénases sont des enzymes impliquées dans les réactions d'oxydoréduction des voies métaboliques, jouant un rôle central dans la production d'énergie et la respiration cellulaire. Ces enzymes sont cruciales pour des processus tels que le cycle de l'acide citrique, la glycolyse et l'oxydation des acides gras. Les inhibiteurs de déshydrogénases sont des outils importants dans l'étude des maladies métaboliques, du cancer et du stress oxydatif. Chez CymitQuimica, nous proposons une sélection complète d'inhibiteurs de déshydrogénases pour soutenir vos recherches en métabolisme, biologie du cancer et biochimie.
322 produits trouvés pour "Déshydrogénase".
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MF-438
CAS :MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1).Formule :C19H18F3N5OSDegré de pureté :98.98% - 99.50%Couleur et forme :SolidMasse moléculaire :421.439CBR-5884
CAS :CBR-5884: active PHGDH inhibitor, IC50=33μM, disrupts serine synthesis, selectively targets high-serine cancers.Formule :C14H12N2O4S2Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :336.38618β-Glycyrrhetyl-3-O-sulfate
CAS :18β-Glycyrrhetyl-3-O-sulfate (Glycyrrhetic acid 3-O-(hydrogen sulfate)), a major metabolite of Glycyrrhetinic acid (GA), serves as a potent inhibitor of type 2Formule :C30H46O7SCouleur et forme :SolidMasse moléculaire :550.75PHGDH-IN-5
CAS :Compound B12 (PHGDH-IN-5) acts as a covalent inhibitor of PHGDH, demonstrating an IC50 value of 0.29 μM. It has been shown to inhibit the proliferation of cancer cell lines that overexpress PHGDH and reduce the production of glucose-derived serine in MDA-MB-468 cells [1].Formule :C8H5NO4SCouleur et forme :SolidMasse moléculaire :211.20DHODH-IN-18
CAS :DHODH-IN-18 is a human DHODH inhibitor ( IC 50 = 0.2 nM).Formule :C21H16ClF5N6O4Couleur et forme :SolidMasse moléculaire :546.84SCD1 inhibitor-3
CAS :SCD1 inhibitor-3 (ML-270) is a highly effective and orally available compound that inhibits SCD1 with remarkable safety.Formule :C19H16FN7O2Degré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :393.3744LDH-IN-3
LDH-IN-3 (compound E38) is an inhibitor of lactate dehydrogenase (LDH) and a potential protective agent against ischemic neuronal damage in the eyes and brain. It functions through the HO-1/SIRT1 pathway.Formule :C32H27NO5Couleur et forme :SolidMasse moléculaire :505.56hDHODH-IN-12
hDHODH-IN-12 is a potent inhibitor of dihydroorotate dehydrogenase (DHODH), exhibiting an inhibitory concentration (IC50) of 0.421 μM.Formule :C22H15F3N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :440.3711β-HSD1-IN-11
CAS :11β-HSd1-in-11 is a potent and competitive inhibitor of 11-β-hydroxysteroid dehydrogenase 1 (11β-HSD1) IN rats and humans with IC50 values of 0.34 μM and 0.13Formule :C15H11F3O3SDegré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :328.306PDK-IN-2
PDK-IN-2 (Compound 1F), with an IC50 of 68 nM, is a potent PDK inhibitor that downregulates the expression of PDK1 and PDK4 in cells.Formule :C17H23AsCl2N2O2S2Couleur et forme :SolidMasse moléculaire :497.33MTHFD2-IN-3
MTHFD2-IN-3 (compound 10), a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2), demonstrates significant efficacy in obstructing the activityFormule :C22H19NO7SCouleur et forme :SolidMasse moléculaire :441.45MTHFD2-IN-1
MTHFD2-IN-1 (compound 12) is a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2) [1].Formule :C24H21NO6Couleur et forme :SolidMasse moléculaire :419.43MTHFD2-IN-4 sodium
MTHFD2-IN-4 sodium, a potent inhibitor of MTHFD2 and a tricyclic coumarin derivative, is applicable in cancer research [1].Formule :C26H21F6N2NaO5Couleur et forme :SolidMasse moléculaire :578.44Succinate dehydrogenase-IN-4
Succinate dehydrogenase-IN-4 (Compound 4b) is an inhibitor of succinate dehydrogenase with an IC50 value of 3.38 μM. It exhibits antifungal activity against Physalospora piricola and Colletotrichum orbiculare, with EC50 values of 16.33 μM and 18.06 μM, respectively.Formule :C20H21N3O2S2Couleur et forme :SolidMasse moléculaire :399.531H-Tetrazole
CAS :1H-Tetrazole is a tetrazole heterocycle, a carboxyl bioisostere that inhibits 11β-HSD1 and mitochondrial function.Formule :CH2N4Masse moléculaire :70.05LDHA-IN-10
LDHA-IN-10 (Compound HP19) is an inhibitor of lactate dehydrogenase A (LDHA) with an IC50 value of 5.2 μM. It reduces lactate production and ATP levels, inhibiting the proliferation of the pancreatic cancer cell line PANC-1. Additionally, LDHA-IN-10 induces G1/S cell cycle arrest and promotes apoptosis, showing potential for research in pancreatic ductal adenocarcinoma (PDAC).ALDH1A1-IN-5
ALDH1A1-IN-5 (compound 25) is a potent inhibitor of aldehyde dehydrogenase 1A1 (ALDH1A1), exhibiting EC50 values of 83 µM, 45 µM, and 43 µM for ALDH1A1, ALDH1A2, and ALDH1A3, respectively. This compound holds potential for research in high-grade serous ovarian cancer (HGSOC).Formule :C18H17Cl2N3O2Masse moléculaire :377.06978DHODH-IN-23
CAS :DHODH-IN-23 is a DHODH inhibitor with oral activity. DHODH-IN-23 is often used in cancer research.Formule :C24H21ClFNO4Degré de pureté :99.7%Couleur et forme :SolidMasse moléculaire :441.879LDHA-IN-3
CAS :LDHA-IN-3 is a potent selenobenzene-based LDHA inhibitor with a 145.2 nM IC50, useful in cancer research.Formule :C13H9F3SeDegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :301.17BMS-770767
CAS :BMS-770767 is a novel 11-betahydroxysteroid dehydrogenase type I (11ß-HSD1) inhibitor.Formule :C19H18ClN3O2Couleur et forme :SolidMasse moléculaire :355.82
