Déshydrogénase
Les déshydrogénases sont des enzymes impliquées dans les réactions d'oxydoréduction des voies métaboliques, jouant un rôle central dans la production d'énergie et la respiration cellulaire. Ces enzymes sont cruciales pour des processus tels que le cycle de l'acide citrique, la glycolyse et l'oxydation des acides gras. Les inhibiteurs de déshydrogénases sont des outils importants dans l'étude des maladies métaboliques, du cancer et du stress oxydatif. Chez CymitQuimica, nous proposons une sélection complète d'inhibiteurs de déshydrogénases pour soutenir vos recherches en métabolisme, biologie du cancer et biochimie.
303 produits trouvés pour "Déshydrogénase"
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CAY10566
CAS :CAY10566 is a potent SCD1 inhibitor, orally bioavailable, with IC50s: HepG2 cells, 7.9nM; mouse, 4.5nM; human, 26nM.Formule :C18H17ClFN5O2Degré de pureté :99.5% - 99.54%Couleur et forme :SolidMasse moléculaire :389.81Ref: TM-T14878
1mg48,00€1mL*10mM (DMSO)112,00€5mg131,00€10mg195,00€25mg353,00€50mg505,00€100mg710,00€200mg954,00€DHODH-IN-11
CAS :DHODH-IN-11 is a leflunomide derivative and weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03.Formule :C15H11N3O2Degré de pureté :98.14%Couleur et forme :SolidMasse moléculaire :265.27BAY-2402234
CAS :BAY-2402234: a selective DHODH inhibitor targeting myeloid cancers with low-nanomolar potency.Formule :C21H18ClF5N4O4Degré de pureté :98.9%Couleur et forme :SolidMasse moléculaire :520.84Ref: TM-T14501
1mg170,00€2mg234,00€5mg349,00€1mL*10mM (DMSO)401,00€10mg537,00€25mg858,00€50mg1.161,00€100mg1.558,00€IGUANA-1 free base
CAS :IGUANA-1: selective ALDH1 B1 inhibitor, IC50=30 nM, hinders SW480 cell growth with IC50=2.46/0.39 μM in adherent/spheroid forms, for cancer research.Formule :C26H24ClN3O2Couleur et forme :SolidMasse moléculaire :445.94WAY-311610
CAS :WAY-311610 is an HSD11B1 inhibitor targeting 11β-HSD1 enzyme with 0.34 μM IC; used for neuropathic and inflammatory pain research.Formule :C16H13F3N4O2Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :350.3PDK-IN-1
CAS :PDK-IN-1, a PDK inhibitor, IC50: 0.03μM (PDK1), 0.1μM (HSP90), reduces tumor mass.Formule :C20H16BrN7OCouleur et forme :SolidMasse moléculaire :450.29MTHFD2-IN-4
MTHFD2-IN-4, a tricyclic coumarin derivative, serves as a potent inhibitor of MTHFD2 and has applications in cancer research [1].Formule :C26H21F6N2O5Couleur et forme :SolidMasse moléculaire :555.45MTHFD2-IN-2
MTHFD2-IN-2 (compound 13) serves as a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2) [1].Formule :C22H18N4O5Couleur et forme :SolidMasse moléculaire :418.4LDHA-IN-3
CAS :LDHA-IN-3 is a potent selenobenzene-based LDHA inhibitor with a 145.2 nM IC50, useful in cancer research.Formule :C13H9F3SeDegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :301.17Ref: TM-T39805
1mg52,00€5mg113,00€1mL*10mM (DMSO)124,00€10mg177,00€25mg371,00€50mg517,00€100mg707,00€200mg973,00€hDHODH-IN-13
CAS :hDHODH-IN-13 (compound w2), an inhibitor of human dihydroorotate dehydrogenase (hDHODH), exhibits an IC50 of 173.4 nM and has potential research applications inCouleur et forme :SoildCM121
CAS :CM121, a reversible ALDH1A2 inhibitor, targets active site with IC50=0.54μM, Kd=1.1μM, using hydrophobic interactions.Formule :C24H17FN4O3SCouleur et forme :SolidMasse moléculaire :460.48DHODH-IN-18
CAS :DHODH-IN-18 is a human DHODH inhibitor ( IC 50 = 0.2 nM).Formule :C21H16ClF5N6O4Couleur et forme :SolidMasse moléculaire :546.84D-Lactate dehydrogenase
CAS :D-LDH is an oxidoreductase turning D-lactate into pyruvate, using NAD+/NADP+; prevalent in bacteria and fungi, key for biochemical research.Couleur et forme :SolidMTHFD2-IN-1
MTHFD2-IN-1 (compound 12) is a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2) [1].Formule :C24H21NO6Couleur et forme :SolidMasse moléculaire :419.43Necroptosis-IN-3
CAS :Necroptosis-IN-3 (Cyclohexanecarboxamide, N-(2-thienylmethyl)-) (Compound 69) is a Necroptosis inhibitor that inhibits TNF-α induced necroptosis.Formule :C12H17NOSDegré de pureté :99.85%Couleur et forme :SoildMasse moléculaire :223.33PDK-IN-2
PDK-IN-2 (Compound 1F), with an IC50 of 68 nM, is a potent PDK inhibitor that downregulates the expression of PDK1 and PDK4 in cells.Formule :C17H23AsCl2N2O2S2Couleur et forme :SolidMasse moléculaire :497.3311β-HSD1-IN-11
CAS :11β-HSd1-in-11 is a potent and competitive inhibitor of 11-β-hydroxysteroid dehydrogenase 1 (11β-HSD1) IN rats and humans with IC50 values of 0.34 μM and 0.13Formule :C15H11F3O3SDegré de pureté :99.61%Couleur et forme :SoildMasse moléculaire :328.31Ref: TM-T60149
1mg109,00€1mL*10mM (DMSO)239,00€5mg241,00€10mg355,00€25mg532,00€50mg745,00€100mg1.018,00€500mg2.043,00€Ascochlorin A
CAS :Ascochlorin A, a compound with a dissociation constant (K D) of 3.29 μM, serves as a novel and potent human dihydroorotate dehydrogenase (hDHODH) inhibitorFormule :C23H31ClO4Couleur et forme :SolidMasse moléculaire :406.95hDHODH-IN-12
hDHODH-IN-12 is a potent inhibitor of dihydroorotate dehydrogenase (DHODH), exhibiting an inhibitory concentration (IC50) of 0.421 μM.Formule :C22H15F3N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :440.372,3-Dihydroxybenzaldehyde
CAS :2,3-Dihydroxybenzaldehyde exhibits activity against NADH dehydrogenase (Km = 35 µM) and can be used in biochemical experiments and drug synthesis.Formule :C7H6O3Couleur et forme :SolidMasse moléculaire :138.12
