Déshydrogénase
Les déshydrogénases sont des enzymes impliquées dans les réactions d'oxydoréduction des voies métaboliques, jouant un rôle central dans la production d'énergie et la respiration cellulaire. Ces enzymes sont cruciales pour des processus tels que le cycle de l'acide citrique, la glycolyse et l'oxydation des acides gras. Les inhibiteurs de déshydrogénases sont des outils importants dans l'étude des maladies métaboliques, du cancer et du stress oxydatif. Chez CymitQuimica, nous proposons une sélection complète d'inhibiteurs de déshydrogénases pour soutenir vos recherches en métabolisme, biologie du cancer et biochimie.
303 produits trouvés pour "Déshydrogénase"
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MTHFD2-IN-3
MTHFD2-IN-3 (compound 10), a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2), demonstrates significant efficacy in obstructing the activityFormule :C22H19NO7SCouleur et forme :SolidMasse moléculaire :441.45(Rac)-BMS-816336
(Rac)-BMS-816336 is a racemic 11β-HSD1 inhibitor; IC50: 10 nM (human), 68 nM (mouse), metabolically stable.Formule :C21H27NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :341.44IGUANA-1
CAS :IGUANA-1 is a highly efficient and selective ALDH1B1 inhibitor that inhibits the growth of colorectal cancer cells and colorectal cancer cell-derived organoids.Formule :C27H26ClN3O4Degré de pureté :99.08%Couleur et forme :SolidMasse moléculaire :491.97Ref: TM-T73377
1mg86,00€5mg180,00€1mL*10mM (DMSO)188,00€10mg283,00€25mg530,00€50mg797,00€100mg1.159,00€DSM705
CAS :DSM705: Pyrrole-based, potent nanomolar Plasmodium DHODH inhibitor with strong antimalarial efficacy; spares mammalian DHODH.Formule :C19H19F3N6OCouleur et forme :SolidMasse moléculaire :404.397Octanoyl Coenzyme A (sodium salt)
Octanoyl Coenzyme A (sodium salt) inhibits citrate synthase and glutamate dehydrogenase with an IC50 of 0.4–1.6 mM.Formule :C29H49N7NaO17P3SCouleur et forme :SolidMasse moléculaire :915.71MTHFD2-IN-4 sodium
MTHFD2-IN-4 sodium, a potent inhibitor of MTHFD2 and a tricyclic coumarin derivative, is applicable in cancer research [1].Formule :C26H21F6N2NaO5Couleur et forme :SolidMasse moléculaire :578.44hDHODH-IN-12
hDHODH-IN-12 is a potent inhibitor of dihydroorotate dehydrogenase (DHODH), exhibiting an inhibitory concentration (IC50) of 0.421 μM.Formule :C22H15F3N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :440.37D-Lactate dehydrogenase
CAS :D-LDH is an oxidoreductase turning D-lactate into pyruvate, using NAD+/NADP+; prevalent in bacteria and fungi, key for biochemical research.Couleur et forme :SolidBMS-770767
CAS :BMS-770767 is a novel 11-betahydroxysteroid dehydrogenase type I (11ß-HSD1) inhibitor.Formule :C19H18ClN3O2Couleur et forme :SolidMasse moléculaire :355.82IGUANA-1 free base
CAS :IGUANA-1: selective ALDH1 B1 inhibitor, IC50=30 nM, hinders SW480 cell growth with IC50=2.46/0.39 μM in adherent/spheroid forms, for cancer research.Formule :C26H24ClN3O2Couleur et forme :SolidMasse moléculaire :445.94SCD1 inhibitor-3
CAS :SCD1 inhibitor-3 (ML-270) is a highly effective and orally available compound that inhibits SCD1 with remarkable safety.Formule :C19H16FN7O2Degré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :393.37Ref: TM-T38683
1mg87,00€5mg177,00€1mL*10mM (DMSO)195,00€10mg281,00€25mg480,00€50mg692,00€100mg973,00€PDK-IN-2
PDK-IN-2 (Compound 1F), with an IC50 of 68 nM, is a potent PDK inhibitor that downregulates the expression of PDK1 and PDK4 in cells.Formule :C17H23AsCl2N2O2S2Couleur et forme :SolidMasse moléculaire :497.3311β-HSD1 inibitor 17
CAS :11β-HSD1 inibitor 17 is an inhibitor of 11β-hydroxysteroid dehydrogenase (11β-HSD1).Formule :C22H20F3N3O2SDegré de pureté :99.26% - 99.72%Couleur et forme :SoildMasse moléculaire :447.47LDHA-IN-3
CAS :LDHA-IN-3 is a potent selenobenzene-based LDHA inhibitor with a 145.2 nM IC50, useful in cancer research.Formule :C13H9F3SeDegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :301.17Ref: TM-T39805
1mg52,00€5mg113,00€1mL*10mM (DMSO)124,00€10mg177,00€25mg371,00€50mg517,00€100mg707,00€200mg973,00€WAY-311610
CAS :WAY-311610 is an HSD11B1 inhibitor targeting 11β-HSD1 enzyme with 0.34 μM IC; used for neuropathic and inflammatory pain research.Formule :C16H13F3N4O2Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :350.3DSM1465
DSM1465 (Compound 82) is a potent and selective inhibitor of P. falciparum dihydroorotate dehydrogenase (PfDHODH) with an IC50 value of 15 nM. It inhibits P. falciparum 3D7 (Pf3D7) parasites with an EC50 value of 1.4 nM and demonstrates significant in vivo efficacy in humanized P. falciparum mouse models.Formule :C17H12ClF6N5O2Couleur et forme :SolidMasse moléculaire :467.753DHODH-IN-18
CAS :DHODH-IN-18 is a human DHODH inhibitor ( IC 50 = 0.2 nM).Formule :C21H16ClF5N6O4Couleur et forme :SolidMasse moléculaire :546.8418β-Glycyrrhetyl-3-O-sulfate
CAS :18β-Glycyrrhetyl-3-O-sulfate (Glycyrrhetic acid 3-O-(hydrogen sulfate)), a major metabolite of Glycyrrhetinic acid (GA), serves as a potent inhibitor of type 2Formule :C30H46O7SCouleur et forme :SolidMasse moléculaire :550.75MCI-INI-3
CAS :MCI-INI-3 is a selective competitive inhibitor of human ALDH1A3, with a Ki value of 0.55 μM for ALDH1A3 and 78.2 μM for ALDH1A1. It inhibits retinoic acid biosynthesis and can reduce the viability of glioblastoma cells GSC-83 and GSC-326.Formule :C21H15N3O4Couleur et forme :SolidMasse moléculaire :373.36PDK-IN-1
CAS :PDK-IN-1, a PDK inhibitor, IC50: 0.03μM (PDK1), 0.1μM (HSP90), reduces tumor mass.Formule :C20H16BrN7OCouleur et forme :SolidMasse moléculaire :450.29
