Déshydrogénase
Les déshydrogénases sont des enzymes impliquées dans les réactions d'oxydoréduction des voies métaboliques, jouant un rôle central dans la production d'énergie et la respiration cellulaire. Ces enzymes sont cruciales pour des processus tels que le cycle de l'acide citrique, la glycolyse et l'oxydation des acides gras. Les inhibiteurs de déshydrogénases sont des outils importants dans l'étude des maladies métaboliques, du cancer et du stress oxydatif. Chez CymitQuimica, nous proposons une sélection complète d'inhibiteurs de déshydrogénases pour soutenir vos recherches en métabolisme, biologie du cancer et biochimie.
303 produits trouvés pour "Déshydrogénase"
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hDHODH-IN-13
CAS :hDHODH-IN-13 (compound w2), an inhibitor of human dihydroorotate dehydrogenase (hDHODH), exhibits an IC50 of 173.4 nM and has potential research applications inCouleur et forme :SoildPDK-IN-2
PDK-IN-2 (Compound 1F), with an IC50 of 68 nM, is a potent PDK inhibitor that downregulates the expression of PDK1 and PDK4 in cells.Formule :C17H23AsCl2N2O2S2Couleur et forme :SolidMasse moléculaire :497.33KOTX1
CAS :KOTX1 is an orally active and selective inhibitor of ALDH1A3. In a diabetic mouse model, KOTX1 improves glucose tolerance, insulin secretion, and blood glucose levels.Formule :C17H16FN3O2Couleur et forme :SolidMasse moléculaire :313.33D-Lactate dehydrogenase
CAS :D-LDH is an oxidoreductase turning D-lactate into pyruvate, using NAD+/NADP+; prevalent in bacteria and fungi, key for biochemical research.Couleur et forme :SolidMCI-INI-3
CAS :MCI-INI-3 is a selective competitive inhibitor of human ALDH1A3, with a Ki value of 0.55 μM for ALDH1A3 and 78.2 μM for ALDH1A1. It inhibits retinoic acid biosynthesis and can reduce the viability of glioblastoma cells GSC-83 and GSC-326.Formule :C21H15N3O4Couleur et forme :SolidMasse moléculaire :373.36Necroptosis-IN-3
CAS :Necroptosis-IN-3 (Cyclohexanecarboxamide, N-(2-thienylmethyl)-) (Compound 69) is a Necroptosis inhibitor that inhibits TNF-α induced necroptosis.Formule :C12H17NOSDegré de pureté :99.85%Couleur et forme :SoildMasse moléculaire :223.33DHODH-IN-23
CAS :DHODH-IN-23 is a DHODH inhibitor with oral activity. DHODH-IN-23 is often used in cancer research.
Formule :C24H21ClFNO4Degré de pureté :99.7%Couleur et forme :SolidMasse moléculaire :441.88CM121
CAS :CM121, a reversible ALDH1A2 inhibitor, targets active site with IC50=0.54μM, Kd=1.1μM, using hydrophobic interactions.Formule :C24H17FN4O3SCouleur et forme :SolidMasse moléculaire :460.482,3-Dihydroxybenzaldehyde
CAS :2,3-Dihydroxybenzaldehyde exhibits activity against NADH dehydrogenase (Km = 35 µM) and can be used in biochemical experiments and drug synthesis.Formule :C7H6O3Couleur et forme :SolidMasse moléculaire :138.12Osmanthuside H
CAS :Osmanthuside H is a useful organic compound for research related to life sciences. The catalog number is T125796 and the CAS number is 149155-70-4.Formule :C19H28O11Couleur et forme :SolidMasse moléculaire :432.422WQQ-345
WQQ-345, a BCAT1 inhibitor, exhibits an IC50 of 10.8 mM. In 67R cells, it reduces α-KG levels and upregulates H3K27me3 expression while downregulating the expression of glycolytic enzymes (PFKP and LDHA), leading to impaired glycolytic activity. Additionally, WQQ-345 demonstrates tumor-suppressive activity in a 67R subcutaneous xenograft model.Formule :C10H17NO2Couleur et forme :SolidMasse moléculaire :183.25SCD1 inhibitor-3
CAS :SCD1 inhibitor-3 (ML-270) is a highly effective and orally available compound that inhibits SCD1 with remarkable safety.Formule :C19H16FN7O2Degré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :393.37Ref: TM-T38683
1mg87,00€5mg177,00€1mL*10mM (DMSO)195,00€10mg281,00€25mg480,00€50mg692,00€100mg973,00€11β-HSD1-IN-11
CAS :11β-HSd1-in-11 is a potent and competitive inhibitor of 11-β-hydroxysteroid dehydrogenase 1 (11β-HSD1) IN rats and humans with IC50 values of 0.34 μM and 0.13Formule :C15H11F3O3SDegré de pureté :99.61%Couleur et forme :SoildMasse moléculaire :328.31Ref: TM-T60149
1mg109,00€1mL*10mM (DMSO)239,00€5mg241,00€10mg355,00€25mg532,00€50mg745,00€100mg1.018,00€500mg2.043,00€BMS-770767
CAS :BMS-770767 is a novel 11-betahydroxysteroid dehydrogenase type I (11ß-HSD1) inhibitor.Formule :C19H18ClN3O2Couleur et forme :SolidMasse moléculaire :355.82SW209049
CAS :SW209049 is a stearoyl-CoA 9-desaturase inhibitor. SW209049 exhivits potent activity against H2122 cell with IC50 of 0.13uM.Formule :C25H18N2O4SDegré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :442.49Ref: TM-T9859
1mg73,00€5mg149,00€1mL*10mM (DMSO)167,00€10mg213,00€25mg319,00€50mg450,00€100mg605,00€200mg802,00€PDK-IN-1
CAS :PDK-IN-1, a PDK inhibitor, IC50: 0.03μM (PDK1), 0.1μM (HSP90), reduces tumor mass.Formule :C20H16BrN7OCouleur et forme :SolidMasse moléculaire :450.29DSM705
CAS :DSM705: Pyrrole-based, potent nanomolar Plasmodium DHODH inhibitor with strong antimalarial efficacy; spares mammalian DHODH.Formule :C19H19F3N6OCouleur et forme :SolidMasse moléculaire :404.397ALDH1A3-IN-1
CAS :ALDH1A3-IN-1 (Compound 14) is a potent inhibitor of ALDH1A3 which can be used in prostate cancer research (IC50 = 0.63 μM; Ki = 0.46 μM) [1].Formule :C13H18BrNOCouleur et forme :SolidMasse moléculaire :284.19Trilostane-d3
Trilostane-d3 is a deuterium-substituted isotope-labeled compound of Trilostane, usually used as a quantitative tracer. Trilostane is an inhibitor of 3β-HSD.Formule :C20H24D3NO3Couleur et forme :SolidMasse moléculaire :332.45XTT sodium
CAS :XTT sodium is a cell viability detector that can be metabolized by mitochondrial dehydrogenase in live cells to produce a highly colored formic acid product.Formule :C22H16N7NaO13S2Degré de pureté :98.69%Couleur et forme :SolidMasse moléculaire :673.52
