Déshydrogénase
Les déshydrogénases sont des enzymes impliquées dans les réactions d'oxydoréduction des voies métaboliques, jouant un rôle central dans la production d'énergie et la respiration cellulaire. Ces enzymes sont cruciales pour des processus tels que le cycle de l'acide citrique, la glycolyse et l'oxydation des acides gras. Les inhibiteurs de déshydrogénases sont des outils importants dans l'étude des maladies métaboliques, du cancer et du stress oxydatif. Chez CymitQuimica, nous proposons une sélection complète d'inhibiteurs de déshydrogénases pour soutenir vos recherches en métabolisme, biologie du cancer et biochimie.
267 produits trouvés pour "Déshydrogénase"
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BVT-2733 hydrochloride
CAS :<p>BVT-2733 hydrochloride is a potent, selective, and orally active non-steroidal 11β-HSD1 inhibitor. It exhibits stronger inhibition on mouse 11β-HSD1 enzyme (IC50=96 nM) compared to the human 11β-HSD1 enzyme (IC50=3341 nM). BVT-2733 hydrochloride shows potential for research in arthritis and obesity-related diseases.</p>Formule :C17H22Cl2N4O3S2Couleur et forme :SolidMasse moléculaire :465.42MTHFD2-IN-3
<p>MTHFD2-IN-3 (compound 10), a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2), demonstrates significant efficacy in obstructing the activity</p>Formule :C22H19NO7SCouleur et forme :SolidMasse moléculaire :441.45MCI-INI-3
CAS :<p>MCI-INI-3 is a selective competitive inhibitor of human ALDH1A3, with a Ki value of 0.55 μM for ALDH1A3 and 78.2 μM for ALDH1A1. It inhibits retinoic acid biosynthesis and can reduce the viability of glioblastoma cells GSC-83 and GSC-326.</p>Formule :C21H15N3O4Couleur et forme :SolidMasse moléculaire :373.36CM121
CAS :<p>CM121, a reversible ALDH1A2 inhibitor, targets active site with IC50=0.54μM, Kd=1.1μM, using hydrophobic interactions.</p>Formule :C24H17FN4O3SCouleur et forme :SolidMasse moléculaire :460.48DHODH-IN-23
CAS :<p>DHODH-IN-23 is a DHODH inhibitor with oral activity. DHODH-IN-23 is often used in cancer research.</p>Formule :C24H21ClFNO4Degré de pureté :99.7%Couleur et forme :SolidMasse moléculaire :441.88Osmanthuside H
CAS :<p>Osmanthuside H is a useful organic compound for research related to life sciences. The catalog number is T125796 and the CAS number is 149155-70-4.</p>Formule :C19H28O11Couleur et forme :SolidMasse moléculaire :432.422hDHODH-IN-16
<p>hDHODH-IN-16 (Compound 3t) is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an IC50 of 0.11 μM. It demonstrates very low cytotoxicity towards healthy HaCaT cells, with an IC50 value exceeding 200 μM.</p>Formule :C18H20N2O2Couleur et forme :SolidMasse moléculaire :296.36D-Lactate dehydrogenase
CAS :<p>D-LDH is an oxidoreductase turning D-lactate into pyruvate, using NAD+/NADP+; prevalent in bacteria and fungi, key for biochemical research.</p>Couleur et forme :SolidMTHFD2-IN-4
<p>MTHFD2-IN-4, a tricyclic coumarin derivative, serves as a potent inhibitor of MTHFD2 and has applications in cancer research [1].</p>Formule :C26H21F6N2O5Couleur et forme :SolidMasse moléculaire :555.45ALDH1A3-IN-1
CAS :<p>ALDH1A3-IN-1 (Compound 14) is a potent inhibitor of ALDH1A3 which can be used in prostate cancer research (IC50 = 0.63 μM; Ki = 0.46 μM) [1].</p>Formule :C13H18BrNOCouleur et forme :SolidMasse moléculaire :284.192-Bromoacetamide
CAS :<p>2-Bromoacetamide (α-Bromoacetamide) is a class of disinfection by-products that exhibit developmental toxicity in animals.</p>Formule :C2H4BrNODegré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :137.96Ketogestin
CAS :<p>Ketogestin is a progestational steroid and an inhibitor of enzyme 11β-hydroxysteroid dehydrogenase, and a weak negative modulator of GABAA receptors.</p>Formule :C21H28O3Degré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :328.454-Isopropoxybenzaldehyde
CAS :<p>ALDH1A3-IN-3 inhibits ALDH1A3 (IC50: 0.26 μM), acts on ALDH3A1, and is used in prostate cancer research.</p>Formule :C10H12O2Degré de pureté :99.00%Couleur et forme :SolidMasse moléculaire :164.2Aldehyde dehydrogenase (NAD(P))
CAS :<p>ALDH catalyzes oxidation of aldehydes to acids, reducing NAD(P) to NAD(P)H, helping alleviate aldehyde stress.</p>Couleur et forme :SolidDSM265
CAS :<p>DSM265 (PfSPZ) is a dihydroorotic acid dehydrogenase inhibitor with antimalarial activity.DSM265 can be used for the treatment of malaria infections.</p>Formule :C14H12F7N5SDegré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :415.33PKUMDL-WQ-2201
CAS :<p>PKUMDL-WQ-2201 is a selective allosteric inhibitor of phosphoglycerate dehydrogenase (PHGDH) with Anti-tumor Activity, it binds to site II.</p>Formule :C15H14ClN3O3SCouleur et forme :SolidMasse moléculaire :351.81ALDH3A1-IN-1
CAS :<p>ALDH3A1-IN-1 (Compound 18) is a potent inhibitor of ALDH3A1 with IC50 of 1.61 μM, outperforms DEAB in prostate cancer cells.</p>Formule :C13H18N2O3Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :250.29ABT-384
CAS :<p>ABT-384 is a high-affinity, selective 11β-HSD1 inhibitor capable of suppressing hepatic and central nervous system HSD-1 activity for depressive disorder.</p>Formule :C25H34F3N5O2Degré de pureté :99.863%Couleur et forme :SolidMasse moléculaire :493.58ALDH1A2-IN-1
CAS :<p>ALDH1A2-IN-1 is a reversible active-site-directed ALDH1A2 inhibitor preventing spermatogenesis, useful in male contraceptive research.</p>Formule :C21H26N4O4SDegré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :430.52DSM502
CAS :<p>DSM502 DSM502 is a dihydroorotic acid dehydrogenase (DHODH) inhibitor with antimalarial activity that inhibits Plasmodium DHODH and can be used as a lead for antimalarial compounds.</p>Formule :C16H16F3N3ODegré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :323.31
