Lipoxygénase
Les lipoxygénases sont une famille d'enzymes qui catalysent l'oxygénation des acides gras polyinsaturés, conduisant à la production de médiateurs lipidiques bioactifs tels que les leucotriènes et les lipoxines. Ces médiateurs jouent un rôle crucial dans l'inflammation, les réponses immunitaires et le cancer. Les inhibiteurs de la lipoxygénase sont utilisés pour étudier leur rôle dans les maladies inflammatoires, l'asthme et le cancer. Chez CymitQuimica, nous proposons une variété d'inhibiteurs de la lipoxygénase pour soutenir vos recherches en inflammation, oncologie et métabolisme lipidique.
124 produits trouvés pour "Lipoxygénase"
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Zileuton
CAS :<p>Zileuton (A 64077) inhibits 5-lipoxygenase, reduces leukotrienes, aids bronchodilation, lessens mucus/edema, and helps manage asthma symptoms.</p>Formule :C11H12N2O2SDegré de pureté :98.72% - 99.43%Couleur et forme :Crystalline SolidMasse moléculaire :236.29Meclofenoxate hydrochloride
CAS :<p>Meclofenoxate HCl (Lucidril) boosts memory and cognition; it's a DIMETHYLAMINOETHANOL and p-chlorophenoxyacetic acid ester.</p>Formule :C12H16ClNO3·HClDegré de pureté :97.05%Couleur et forme :White Crystal PowderMasse moléculaire :294.17Diethylcarbamazine citrate
CAS :<p>Diethylcarbamazine citrate treats filariasis, targeting W. bancrofti and L. loa by inhibiting arachidonic acid in microfilaria.</p>Formule :C10H21N3O·C6H8O7Degré de pureté :99.61%Couleur et forme :White Crystalline Powder And Animals (Epa 1998)Masse moléculaire :391.42mPGES-1/5-LOX-IN-1
<p>mPGES-1/5-LOX-IN-1 (compound 3j) is a potent, orally active dual inhibitor of mPGES-1 and 5-LOX, with IC50 values of 0.92 and 1.89 µM, respectively. Additionally, mPGES-1/5-LOX-IN-1 exhibits anti-inflammatory properties.</p>Formule :C20H22N4O6SMasse moléculaire :446.12601Damnacanthol
<p>Damnacanthol is a useful organic compound for research related to life sciences and the catalog number is T131609.</p>Formule :C16H12O5Couleur et forme :SolidMasse moléculaire :284.267Lipoxygenase
CAS :<p>Lipoxygenase (LOX) is a dioxygenase that catalyzes the peroxidation of linoleic acid (LA) or arachidonic acid (AA) in the presence of molecular oxygen.</p>Couleur et forme :SolidCMI977
CAS :<p>CMI977 is a potent inhibitor of 5-Lipoxygenase (5-LO).</p>Formule :C16H19FN2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :322.3315-LOX-1 inhibitor 1
CAS :<p>9c(i472) blocks 15-LO-1 (IC50=0.19μM), lowers NF-κB in RAW-Blue cells, & cuts Nos2/lipid peroxidation in RAW 264.7 at 0.2-5μM.</p>Formule :C22H21ClN2O4Couleur et forme :SolidMasse moléculaire :412.875-LOX/NO-IN-1
<p>5-LOX/NO-IN-1 (Compound 7e) is a dual inhibitor of 5-LOX and nitric oxide release. It exhibits an IC50 value of 2.833 μM for 5-LOX and demonstrates anti-inflammatory properties.</p>Formule :C22H18N6O4Couleur et forme :SolidMasse moléculaire :430.42DKI5
CAS :<p>DKI5, a LOX-1 inhibitor with 22.5 μM IC50, may exhibit anti-inflammatory, antioxidant, and anti-lipid peroxidation effects in vitro.</p>Formule :C8H10N4SDegré de pureté :98%Couleur et forme :SoildMasse moléculaire :194.26h15-LOX-2 inhibitor 2
<p>Compound 10 (h15-LOX-2 inhibitor 2) suppresses h15-LOX activity, exhibiting IC 50 and K i values of 26.9 μM and 16.4 μM, respectively.</p>Formule :C22H30Cl2N6O3Couleur et forme :SolidMasse moléculaire :497.42ThioLox
CAS :<p>ThioLox, a 15-LOX-1 inhibitor (IC50: 12 μM), has anti-inflammatory, neuroprotective benefits, and guards against glutamate toxicity.</p>Formule :C15H18N2OSDegré de pureté :99.98%Couleur et forme :SoildMasse moléculaire :274.38Ruthenoleuton
<p>Ruthenoleuton is a 5-lipoxygenase (5-LOX) inhibitor with an IC50 of 3.49 μM and a Ki of 0.80 μM. It possesses antioxidant properties and is applicable in research on inflammatory diseases.</p>Formule :C13H16N2O2RuCouleur et forme :SolidMasse moléculaire :333.35Aureusidin
CAS :<p>Aureusidin (Auresidin) shows antioxidant and lipoxygenase inhibitory activity with anti-inflammatory effects.</p>Formule :C15H10O6Degré de pureté :98.17% - 99.18%Couleur et forme :SolidMasse moléculaire :286.24CJ-13,610 hydrochloride
CAS :<p>CJ-13,610 hydrochloride is an orally active nonredox-type inhibitor of 5-LOX and can be used in studies about the prevention of untoward pathophysiological</p>Formule :C22H24ClN3O2SDegré de pureté :98.5%Couleur et forme :SoildMasse moléculaire :429.96Ferroleuton
<p>Ferroleuton is a selective competitive inhibitor of 5-lipoxygenase with an IC50 of 0.21 μM. It demonstrates antioxidant properties, clearing 86% of DPPH at 50 μM and exhibiting activities in ABTS (EC50 = 19.42 μM) and FRAP (EC50 = 3.32 μM) assays.</p>Formule :C13H16FeN2O2Couleur et forme :SolidMasse moléculaire :288.125-LOX-IN-5
<p>Compound 29, also known as 5-LOX-IN-5, is a 5-lipoxygenase (5-LOX) inhibitor with an inhibitory concentration 50 (IC50) of 56 nM, utilized in research</p>Formule :C19H18BrN3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :432.33LOX-IN-5
CAS :<p>LOX-IN-5 (compound 22) is a non-selective LOX inhibitor.</p>Formule :C21H25FN4O2SCouleur et forme :SolidMasse moléculaire :416.51(±)15-HEDE
CAS :<p>(±)15-HEDE is produced by non-enzymatic oxidation of 11,14-eicosadienoic acid.</p>Formule :C20H36O3Couleur et forme :SolidMasse moléculaire :324.50513-epi-12-oxo Phytodienoic Acid
CAS :<p>13-epi-12-oxo PDA is a lipoxygenase derivative of α-linolenic acid in green plant leaves, often isomerizing during extraction and storage.</p>Formule :C18H28O3Couleur et forme :SolidMasse moléculaire :292.41Myxochelin A
CAS :<p>Myxochelin A from A. disciformis fights Gram-positive bacteria, inhibits 5-LO with IC50 of 1.9 μM, and is cytotoxic to colon cancer cells.</p>Formule :C20H24N2O7Couleur et forme :SolidMasse moléculaire :404.4191-Naphthyl 3,5-dinitrobenzoate
CAS :<p>1-Naphthyl 3,5-dinitrobenzoate (JMC-4) is an inhibitor of 5-LOX can be used in studies about inflammatory therapy.</p>Formule :C17H10N2O6Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :338.27(-)-Dihydroguaiaretic acid
<p>(-)-Dihydroguaiaretic acid is a useful organic compound for research related to life sciences and the catalog number is T126154.</p>Formule :C20H26O4Couleur et forme :SolidMasse moléculaire :330.424ZD-2138
CAS :<p>ZD-2138: Selective 5-LOX inhibitor, eases allergen-induced asthma attacks and airway constriction in guinea pigs.</p>Formule :C23H24FNO4Degré de pureté :99.68% - >99.99%Couleur et forme :SolidMasse moléculaire :397.44Lagunamycin
CAS :<p>Lagunamycin is used as a novel 5-lipoxygenase inhibitor.</p>Formule :C19H21N3O4Couleur et forme :SolidMasse moléculaire :355.392-Methyl-1-naphthol
CAS :<p>2-Methyl-1-naphthol is a prostaglandin G/H synthase and polyunsaturated fatty acid 5-lipoxygenase inhibitor, suitable for biochemical experiments.</p>Formule :C11H10ODegré de pureté :98.33%Couleur et forme :SolidMasse moléculaire :158.2KKII5
CAS :<p>KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers of</p>Formule :C16H14N2SDegré de pureté :99.34%Couleur et forme :SolidMasse moléculaire :266.36E 6080 HCl
CAS :<p>E 6080 HCl is a 5-lipoxygenase inhibitor and can be used to study bronchial diseases.</p>Formule :C17H20ClN3O3S2Degré de pureté :99.80%Couleur et forme :SoildMasse moléculaire :413.945-Lipoxygenase-IN-3
CAS :<p>Compound 14, a <1 μM 5-lipoxygenase inhibitor, researches inflammation, cancer, stroke, Alzheimer's.</p>Formule :C19H16ClN5OCouleur et forme :SolidMasse moléculaire :365.82Caffeoylcalleryanin
CAS :<p>Caffeoylcalleryanin demonstrated potent inhibitory activity against 15-lipoxygenase (15-LOX), with an IC50 value of 1.59 μM. Furthermore, ethanol extract from A. pulchra leaves (EEAPL) was found to contain compounds exhibiting antiviral properties, particularly effective against Dengue virus type 2 (DENV-2). Among these compounds, Caffeoylcalleryanin emerged as the most potent anti-DENV-2 agent, achieving a selectivity index (SI) of 20.0.</p>Formule :C22H24O11Couleur et forme :SolidMasse moléculaire :464.4CBS-1114 HCl
CAS :<p>CBS-1114 HCl: 5-lipoxygenase inhibitor, anti-inflammatory, improves heart function, reduces heart's fat.</p>Formule :C13H14ClN3Degré de pureté :99.36%Couleur et forme :SoildMasse moléculaire :247.72Zileuton sodium
CAS :<p>Zileuton sodium (A 64077 sodium) is a potent and selective inhibitor of 5-lipoxygenase with anti-inflammatory activities.</p>Formule :C11H11N2NaO2SCouleur et forme :SolidMasse moléculaire :258.27Cinnamyl-3,4-dihydroxy-α-cyanocinnamate
CAS :<p>Cinnamyl-3,4-dihydroxy-α-cyanocinnamate (CDC), 12/15-LO inhibitor for diabetes. Affordable Excellence: Reliable Quality You Can Trust</p>Formule :C19H15NO4Couleur et forme :SolidMasse moléculaire :321.33Phenidone
CAS :<p>Phenidone inhibits COX/LOX, reducing rat autoimmune paralysis and lowering blood pressure in hypertensive rats.</p>Formule :C9H10N2ODegré de pureté :97.24%Couleur et forme :White Solid Solid CrystallineMasse moléculaire :162.19Malotilate
CAS :<p>Malotilate (Kantec) is a medicine used for the therapy of liver cirrhosis.</p>Formule :C12H16O4S2Degré de pureté :99.79% - 99.79%Couleur et forme :SolidMasse moléculaire :288.38SKF-86002
CAS :<p>SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).</p>Formule :C16H12FN3SDegré de pureté :98% - 99.85%Couleur et forme :SolidMasse moléculaire :297.35Phenethyl ferulate
CAS :<p>Phenethyl ferulate is a chemopreventive against colon cancer, enhancing apoptosis in tumors and inhibiting COX/5-LOX (IC50: 4.35/5.75 μM).</p>Formule :C18H18O4Degré de pureté :99.88% - 99.91%Couleur et forme :SolidMasse moléculaire :298.33Caffeic Acid
CAS :<p>Caffeic acid is a dual inhibitor of 5-lipoxygenase and TRPV1 ion channels. High-Quality, Low-Cost!</p>Formule :C9H8O4Degré de pureté :98.89% - 99.3%Couleur et forme :Yellow Crystals From Concentrated Aqueous Solutions Alkaline Solns Turn From Yellow To Orange Alkaline Solutions Turn From Yellow To Orange (Ntp 1992)Masse moléculaire :180.164',5-Dihydroxyflavone
CAS :<p>4',5-Dihydroxyflavone is a soybean LOX-1(Ki: 102.6 μM) and yeast α-Glucosidase inhibitor (IC50: 66 μM).</p>Formule :C15H10O4Degré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :254.24BI-0115
CAS :<p>BI-0115 inhibits LOX-1, preventing oxLDL uptake by triggering receptor inhibition and dimer formation.</p>Formule :C15H14ClN3ODegré de pureté :99.34%Couleur et forme :SolidMasse moléculaire :287.74PGS-IN-1
CAS :<p>PGS-IN-1 (KME-4) is a potent inhibitor of prostaglandin synthetase (PGS, IC50: 0.28 μM) and 5-lipoxygenase (IC50: 1.05 μM).</p>Formule :C19H26O3Degré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :302.41Pectolinarigenin
CAS :<p>Pectolinarigenin has hepatoprotective and anti-inflammatory properties, acting through SOD and inhibiting eicosanoids.</p>Formule :C17H14O6Degré de pureté :98.67% - 99.88%Couleur et forme :SolidMasse moléculaire :314.29Indirubin-3'-monoxime
CAS :<p>Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs ( (IC50s: 100/180/250 nM for Cdk5/p35, Cdk1/</p>Formule :C16H11N3O2Degré de pureté :99.55%Couleur et forme :Dark Red SolidMasse moléculaire :277.28S-(+)-Marmesin
CAS :<p>S-(+)-Marmesin (marmesin) is a coumarin originally isolated from the mature bark of A. marmelos,exhibiting COX-2/5-LOX dual inhibitory activity.</p>Formule :C14H14O4Degré de pureté :98.00% - ≥98%Couleur et forme :SolidMasse moléculaire :246.26LOX-IN-3 dihydrochloride
CAS :<p>LOX-IN-3 dihydrochloride is an inhibitor of lysyl oxidase (LOX).</p>Formule :C13H15Cl2FN2O2SDegré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :353.24Psoralidin
CAS :<p>Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally.</p>Formule :C20H16O5Degré de pureté :98% - 99.61%Couleur et forme :SolidMasse moléculaire :336.34ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE
CAS :<p>ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE is useful for preparation and study of hypoxia-selective cytotoxicity of indolequinone antitumor agents.</p>Formule :C12H13NO3Degré de pureté :98.9%Couleur et forme :Off-White To Light Tan Crystalline PowderMasse moléculaire :219.24Nordihydroguaiaretic acid
CAS :<p>Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.</p>Formule :C18H22O4Degré de pureté :97.82% - 99.91%Couleur et forme :SolidMasse moléculaire :302.36β-Aminopropionitrile hydrochloride
CAS :<p>β-Aminopropionitrile hydrochloride is a selective, oral, irreversible inhibitor of lysyl oxidase (LOX) that reduces metastatic seeding potential.</p>Formule :C3H7ClN2Degré de pureté :99.32%Couleur et forme :SolidMasse moléculaire :106.55Xanthatin
CAS :<p>Xanthatin exhibits cytotoxic, antibacterial, antifungal properties, may treat NSCLC, and inhibits melanoma by targeting Wnt/β-catenin and angiogenesis.</p>Formule :C15H18O3Degré de pureté :98.48% - 99.96%Couleur et forme :SolidMasse moléculaire :246.3
