Lipoxygénase
Les lipoxygénases sont une famille d'enzymes qui catalysent l'oxygénation des acides gras polyinsaturés, conduisant à la production de médiateurs lipidiques bioactifs tels que les leucotriènes et les lipoxines. Ces médiateurs jouent un rôle crucial dans l'inflammation, les réponses immunitaires et le cancer. Les inhibiteurs de la lipoxygénase sont utilisés pour étudier leur rôle dans les maladies inflammatoires, l'asthme et le cancer. Chez CymitQuimica, nous proposons une variété d'inhibiteurs de la lipoxygénase pour soutenir vos recherches en inflammation, oncologie et métabolisme lipidique.
133 produits trouvés pour "Lipoxygénase"
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Zileuton
CAS :Zileuton (A 64077) inhibits 5-lipoxygenase, reduces leukotrienes, aids bronchodilation, lessens mucus/edema, and helps manage asthma symptoms.Formule :C11H12N2O2SDegré de pureté :98.72% - 99.43%Couleur et forme :Crystalline SolidMasse moléculaire :236.29CJ-13,610 hydrochloride
CAS :CJ-13,610 hydrochloride is an orally active nonredox-type inhibitor of 5-LOX and can be used in studies about the prevention of untoward pathophysiologicalFormule :C22H24ClN3O2SDegré de pureté :98.5%Couleur et forme :SoildMasse moléculaire :429.96Ref: TM-T27026L
1mg52,00€5mg92,00€10mg158,00€25mg335,00€50mg500,00€100mg705,00€500mg1.485,00€1mL*10mM (DMSO)148,00€Myxochelin A
CAS :Myxochelin A from A. disciformis fights Gram-positive bacteria, inhibits 5-LO with IC50 of 1.9 μM, and is cytotoxic to colon cancer cells.Formule :C20H24N2O7Couleur et forme :SolidMasse moléculaire :404.419KKII5
CAS :KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers ofFormule :C16H14N2SDegré de pureté :99.44%Couleur et forme :SolidMasse moléculaire :266.36Ref: TM-T77288
2mg37,00€5mg56,00€10mg84,00€25mg126,00€50mg197,00€100mg330,00€200mg472,00€1mL*10mM (DMSO)58,00€5-Lipoxygenase-IN-3
CAS :Compound 14, a <1 μM 5-lipoxygenase inhibitor, researches inflammation, cancer, stroke, Alzheimer's.Formule :C19H16ClN5OCouleur et forme :SolidMasse moléculaire :365.82mPGES-1/5-LOX-IN-1
mPGES-1/5-LOX-IN-1 (compound 3j) is a potent, orally active dual inhibitor of mPGES-1 and 5-LOX, with IC50 values of 0.92 and 1.89 µM, respectively. Additionally, mPGES-1/5-LOX-IN-1 exhibits anti-inflammatory properties.Formule :C20H22N4O6SMasse moléculaire :446.12601ThioLox
CAS :ThioLox, a 15-LOX-1 inhibitor (IC50: 12 μM), has anti-inflammatory, neuroprotective benefits, and guards against glutamate toxicity.
Formule :C15H18N2OSDegré de pureté :99.98%Couleur et forme :SoildMasse moléculaire :274.38Caffeoylcalleryanin
CAS :Caffeoylcalleryanin demonstrated potent inhibitory activity against 15-lipoxygenase (15-LOX), with an IC50 value of 1.59 μM. Furthermore, ethanol extract from A. pulchra leaves (EEAPL) was found to contain compounds exhibiting antiviral properties, particularly effective against Dengue virus type 2 (DENV-2). Among these compounds, Caffeoylcalleryanin emerged as the most potent anti-DENV-2 agent, achieving a selectivity index (SI) of 20.0.Formule :C22H24O11Couleur et forme :SolidMasse moléculaire :464.415-LOX-1 inhibitor 1
CAS :9c(i472) blocks 15-LO-1 (IC50=0.19μM), lowers NF-κB in RAW-Blue cells, & cuts Nos2/lipid peroxidation in RAW 264.7 at 0.2-5μM.Formule :C22H21ClN2O4Couleur et forme :SolidMasse moléculaire :412.87CMI977
CAS :CMI977 is a potent inhibitor of 5-Lipoxygenase (5-LO).Formule :C16H19FN2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :322.33Ferroleuton
Ferroleuton is a selective competitive inhibitor of 5-lipoxygenase with an IC50 of 0.21 μM. It demonstrates antioxidant properties, clearing 86% of DPPH at 50 μM and exhibiting activities in ABTS (EC50 = 19.42 μM) and FRAP (EC50 = 3.32 μM) assays.Formule :C13H16FeN2O2Couleur et forme :SolidMasse moléculaire :288.12DKI5
CAS :DKI5, a LOX-1 inhibitor with 22.5 μM IC50, may exhibit anti-inflammatory, antioxidant, and anti-lipid peroxidation effects in vitro.Formule :C8H10N4SDegré de pureté :97.08%Couleur et forme :SoildMasse moléculaire :194.26Lagunamycin
CAS :Lagunamycin is used as a novel 5-lipoxygenase inhibitor.Formule :C19H21N3O4Couleur et forme :SolidMasse moléculaire :355.39(±)15-HEDE
CAS :(±)15-HEDE is produced by non-enzymatic oxidation of 11,14-eicosadienoic acid.Formule :C20H36O3Couleur et forme :SolidMasse moléculaire :324.50513-epi-12-oxo Phytodienoic Acid
CAS :13-epi-12-oxo PDA is a lipoxygenase derivative of α-linolenic acid in green plant leaves, often isomerizing during extraction and storage.Formule :C18H28O3Couleur et forme :SolidMasse moléculaire :292.412-Methyl-1-naphthol
CAS :2-Methyl-1-naphthol is a prostaglandin G/H synthase and polyunsaturated fatty acid 5-lipoxygenase inhibitor, suitable for biochemical experiments.Formule :C11H10ODegré de pureté :98.33%Couleur et forme :SolidMasse moléculaire :158.2LOX-IN-5
CAS :LOX-IN-5 (compound 22) is a non-selective LOX inhibitor.Formule :C21H25FN4O2SCouleur et forme :SolidMasse moléculaire :416.515-LOX-IN-5
Compound 29, also known as 5-LOX-IN-5, is a 5-lipoxygenase (5-LOX) inhibitor with an inhibitory concentration 50 (IC50) of 56 nM, utilized in researchFormule :C19H18BrN3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :432.331-Naphthyl 3,5-dinitrobenzoate
CAS :1-Naphthyl 3,5-dinitrobenzoate (JMC-4) is an inhibitor of 5-LOX can be used in studies about inflammatory therapy.Formule :C17H10N2O6Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :338.27Ref: TM-T21838
5mg54,00€10mg86,00€25mg161,00€50mg245,00€100mg346,00€200mg474,00€1mL*10mM (DMSO)55,00€(-)-Dihydroguaiaretic acid
(-)-Dihydroguaiaretic acid is a useful organic compound for research related to life sciences and the catalog number is T126154.Formule :C20H26O4Couleur et forme :SolidMasse moléculaire :330.4245-LOX/NO-IN-1
5-LOX/NO-IN-1 (Compound 7e) is a dual inhibitor of 5-LOX and nitric oxide release. It exhibits an IC50 value of 2.833 μM for 5-LOX and demonstrates anti-inflammatory properties.Formule :C22H18N6O4Couleur et forme :SolidMasse moléculaire :430.42BLX3887
CAS :BLX3887 selectively inhibits 15-LO-1 (IC50 = 32 nM), not 15-LO-2, less on 5-LO/12-LO, and affects eosinophils and dendritic cells.Formule :C10H5Cl3FN3OCouleur et forme :SolidMasse moléculaire :308.52ZD-2138
CAS :ZD-2138: Selective 5-LOX inhibitor, eases allergen-induced asthma attacks and airway constriction in guinea pigs.Formule :C23H24FNO4Degré de pureté :99.68% - >99.99%Couleur et forme :SolidMasse moléculaire :397.44Lipoxygenase
CAS :Lipoxygenase (LOX) is a dioxygenase that catalyzes the peroxidation of linoleic acid (LA) or arachidonic acid (AA) in the presence of molecular oxygen.Couleur et forme :SolidE 6080 HCl
CAS :E 6080 HCl is a 5-lipoxygenase inhibitor and can be used to study bronchial diseases.Formule :C17H20ClN3O3S2Degré de pureté :99.80%Couleur et forme :SoildMasse moléculaire :413.94Ruthenoleuton
Ruthenoleuton is a 5-lipoxygenase (5-LOX) inhibitor with an IC50 of 3.49 μM and a Ki of 0.80 μM. It possesses antioxidant properties and is applicable in research on inflammatory diseases.Formule :C13H16N2O2RuCouleur et forme :SolidMasse moléculaire :333.35h15-LOX-2 inhibitor 2
Compound 10 (h15-LOX-2 inhibitor 2) suppresses h15-LOX activity, exhibiting IC 50 and K i values of 26.9 μM and 16.4 μM, respectively.Formule :C22H30Cl2N6O3Couleur et forme :SolidMasse moléculaire :497.42Enazadrem phosphate
CAS :Enazadrem phosphate is a bio-active chemical. Detailed information has not been published.Formule :C18H28N3O5PCouleur et forme :SolidMasse moléculaire :397.413-Chloroiminodibenzyl
CAS :Compound PDK0184, with CAS No. 32943-25-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0184 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formule :C14H12ClNMasse moléculaire :229.78(S)-HEPE
CAS :8(S)-HEPE, derived from EPA via lipoxygenase, aids barnacle egg hatching at 10 nM, but it's not confirmed as the natural hatching factor.Formule :C20H30O3Couleur et forme :SolidMasse moléculaire :318.457CBS-1114 HCl
CAS :CBS-1114 HCl: 5-lipoxygenase inhibitor, anti-inflammatory, improves heart function, reduces heart's fat.Formule :C13H14ClN3Degré de pureté :99.93%Couleur et forme :SoildMasse moléculaire :247.72Damnacanthol
Damnacanthol is a useful organic compound for research related to life sciences and the catalog number is T131609.Formule :C16H12O5Couleur et forme :SolidMasse moléculaire :284.267Aureusidin
CAS :Aureusidin (Auresidin) shows antioxidant and lipoxygenase inhibitory activity with anti-inflammatory effects.Formule :C15H10O6Degré de pureté :98.95% - 99.18%Couleur et forme :SolidMasse moléculaire :286.24Ref: TM-TN5634
1mg197,00€5mg400,00€10mg590,00€25mg888,00€50mg1.243,00€100mg1.693,00€1mL*10mM (DMSO)384,00€Zileuton sodium
CAS :Zileuton sodium (A 64077 sodium) is a potent and selective inhibitor of 5-lipoxygenase with anti-inflammatory activities.Formule :C11H11N2NaO2SCouleur et forme :SolidMasse moléculaire :258.27Cinnamyl-3,4-dihydroxy-α-cyanocinnamate
CAS :Cinnamyl-3,4-dihydroxy-α-cyanocinnamate (CDC), 12/15-LO inhibitor for diabetes. Affordable Excellence: Reliable Quality You Can TrustFormule :C19H15NO4Couleur et forme :SolidMasse moléculaire :321.33Chebulagic acid
CAS :Chebulagic acid, isolated from the Terminalia chebula Retz, is a COX-LOX dual inhibitor.Formule :C41H30O27Degré de pureté :97.82% - 99.8%Couleur et forme :SolidMasse moléculaire :954.66Ref: TM-TQ0180
1mg74,00€5mg157,00€10mg225,00€25mg376,00€50mg560,00€100mg798,00€1mL*10mM (DMSO)244,00€4-MMPB
CAS :15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM.Formule :C16H19N5SDegré de pureté :97.18%Couleur et forme :SolidMasse moléculaire :313.42Ref: TM-T8794
2mg34,00€5mg52,00€10mg86,00€25mg156,00€50mg245,00€100mg403,00€200mg568,00€1mL*10mM (DMSO)58,00€Phenidone
CAS :Phenidone inhibits COX/LOX, reducing rat autoimmune paralysis and lowering blood pressure in hypertensive rats.Formule :C9H10N2ODegré de pureté :97.24%Couleur et forme :White Solid Solid CrystallineMasse moléculaire :162.19SKF-86002
CAS :SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).Formule :C16H12FN3SDegré de pureté :98% - 99.85%Couleur et forme :SolidMasse moléculaire :297.35Phenethyl ferulate
CAS :Phenethyl ferulate is a chemopreventive against colon cancer, enhancing apoptosis in tumors and inhibiting COX/5-LOX (IC50: 4.35/5.75 μM).Formule :C18H18O4Degré de pureté :99.88% - 99.91%Couleur et forme :SolidMasse moléculaire :298.33Ref: TM-TN2330
1mg56,00€5mg119,00€10mg192,00€25mg323,00€50mg475,00€100mg687,00€1mL*10mM (DMSO)114,00€Malotilate
CAS :Malotilate (Kantec) is a medicine used for the therapy of liver cirrhosis.Formule :C12H16O4S2Degré de pureté :99.79% - 99.79%Couleur et forme :SolidMasse moléculaire :288.38Psoralidin
CAS :Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally.Formule :C20H16O5Degré de pureté :98% - 99.61%Couleur et forme :SolidMasse moléculaire :336.34Ref: TM-T3399
2mg34,00€5mg50,00€10mg81,00€25mg152,00€50mg230,00€100mg340,00€200mg497,00€1mL*10mM (DMSO)55,00€PGS-IN-1
CAS :PGS-IN-1 (KME-4) is a potent inhibitor of prostaglandin synthetase (PGS, IC50: 0.28 μM) and 5-lipoxygenase (IC50: 1.05 μM).Formule :C19H26O3Degré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :302.41BI-0115
CAS :BI-0115 inhibits LOX-1, preventing oxLDL uptake by triggering receptor inhibition and dimer formation.Formule :C15H14ClN3ODegré de pureté :99.34%Couleur et forme :SolidMasse moléculaire :287.74S-(+)-Marmesin
CAS :S-(+)-Marmesin (marmesin) is a coumarin originally isolated from the mature bark of A. marmelos,exhibiting COX-2/5-LOX dual inhibitory activity.Formule :C14H14O4Degré de pureté :98.00% - ≥98%Couleur et forme :SolidMasse moléculaire :246.26Xanthatin
CAS :Xanthatin exhibits cytotoxic, antibacterial, antifungal properties, may treat NSCLC, and inhibits melanoma by targeting Wnt/β-catenin and angiogenesis.Formule :C15H18O3Degré de pureté :98.48% - 99.96%Couleur et forme :SolidMasse moléculaire :246.3Pectolinarigenin
CAS :Pectolinarigenin has hepatoprotective and anti-inflammatory properties, acting through SOD and inhibiting eicosanoids.Formule :C17H14O6Degré de pureté :98.67% - 99.88%Couleur et forme :SolidMasse moléculaire :314.29Ref: TM-T6S0413
1mg46,00€5mg89,00€10mg154,00€25mg265,00€50mg409,00€100mg620,00€1mL*10mM (DMSO)110,00€Indirubin-3'-monoxime
CAS :Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs ( (IC50s: 100/180/250 nM for Cdk5/p35, Cdk1/Formule :C16H11N3O2Degré de pureté :99.55%Couleur et forme :Dark Red SolidMasse moléculaire :277.28ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE
CAS :ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE is useful for preparation and study of hypoxia-selective cytotoxicity of indolequinone antitumor agents.Formule :C12H13NO3Degré de pureté :98.9%Couleur et forme :Off-White To Light Tan Crystalline PowderMasse moléculaire :219.243-O-Acetyl-11-hydroxy-β-boswellic acid
CAS :3-O-Acetyl-11-hydroxy-beta-boswellic acid is the precursor of 3-O-acetyl-9, 11-dehydro-beta-boswellic acid(a 5-lipoxygenase inhibitor ).Formule :C32H50O5Degré de pureté :98.24%Couleur et forme :SolidMasse moléculaire :514.74
