Phospholipase
Les phospholipases sont un groupe d'enzymes qui hydrolysent les phospholipides en acides gras et autres substances lipophiles, jouant un rôle crucial dans la biologie des membranes et la génération de molécules de signalisation. Les inhibiteurs des phospholipases sont utilisés pour étudier leur rôle dans les maladies inflammatoires, les troubles cardiovasculaires et la neurodégénérescence. Ces inhibiteurs sont également précieux pour explorer les voies de signalisation lipidique et leurs implications dans les mécanismes des maladies. Chez CymitQuimica, nous fournissons une variété d'inhibiteurs de phospholipases pour soutenir vos recherches en inflammation, métabolisme lipidique et signalisation cellulaire.
84 produits trouvés pour "Phospholipase".
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Tris(2,4-di-tert-butylphenyl)phosphate
CAS :Tris(2,4-di-tert-butylphenyl)phosphate (TDTBPP) inhibits secretory phospholipase A2 (sPLA2) with anti-inflammatory effect. Cost-effective and quality-assured.Formule :C42H63O4PDegré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :662.92ML349
CAS :ML349 is an inhibitor of LYPLA2 (IC50: 144 nM). ML349 is an effective and specific acyl protein thioesterase 2 (APT-2) inhibitor (Ki: 120 nM).Formule :C23H22N2O4S2Degré de pureté :99.59% - 99.88%Couleur et forme :SolidMasse moléculaire :454.56Omeprazole
CAS :Omeprazole (Losec) is a proton pump inhibitor (PPI), Omeprazole(Losec) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor.Formule :C17H19N3O3SDegré de pureté :98.43% - 98.48%Couleur et forme :Brown SolidMasse moléculaire :345.42Lp-PLA2-IN-1
CAS :Lp-PLA2-IN-1 suppresses Lp-PLA2, aiding in treating atherosclerosis and Alzheimer's.Formule :C21H17F5N4O3Degré de pureté :99.60%Couleur et forme :White SolidMasse moléculaire :468.38Lansoprazole
CAS :Lansoprazole (A-65006) is a 2, 2, 2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISONFormule :C16H14F3N3O2SDegré de pureté :99.18% - 99.84%Couleur et forme :Yellow SolidMasse moléculaire :369.36Compound 48/80 trihydrochloride
CAS :Compound 48/80 trihydrochloride (C48/80 trihydrochloride) is a mixture of N-methyl-p-methoxyphenethylamine and formaldehyde produced via a condensation reaction.Formule :C32H48Cl3N3O3Degré de pureté :98% - 99.24%Couleur et forme :White SolidMasse moléculaire :629.1AACOCF3
CAS :AACOCF3 (Arachidonyl trifluoromethyl ketone) is a cell-permeable trifluoromethyl ketone analog of arachidonic acid.Formule :C21H31F3ODegré de pureté :99% - 99%Couleur et forme :SolidMasse moléculaire :356.47nSMase2-IN-1
nSMase2-IN-1 is an orally active inhibitor of Neutral sphingomyelinase 2 (nSMase2) with a potent IC50 value of 0.13 ± 0.06 μM.Formule :C12H17N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :247.3DPTIP hydrochloride
CAS :DPTIP hydrochloride is a potent inhibitor of neutral sphingomyelinase (N-SMase 2) that can cross the blood-brain barrier. It acts as an exosome inhibitor with an IC50 value of 30 nM.Formule :C21H19ClN2O3SCouleur et forme :SolidMasse moléculaire :414.91DPTIP
CAS :DPTIP is an effective inhibitor of neutral sphingomyelinase 2 with an IC50 value of 30 nM.Formule :C21H18N2O3SDegré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :378.44Ref: TM-T60043
1mg46,00€2mg59,00€5mg90,00€1mL*10mM (DMSO)90,00€10mg144,00€25mg281,00€50mg462,00€100mg672,00€ASM-IN-3
CAS :ASM-IN-3 (Compound 21b) is a selective acid sphingomyelinase (ASM) inhibitor that can penetrate the blood-brain barrier, with an IC50 of 3.37 μM against purified human ASM. By inhibiting ASM activity in the hippocampus and promoting neurogenesis, ASM-IN-3 alleviates depressive-like behavior in reserpine-induced depressive rats.Formule :C17H13ClN2O4Couleur et forme :SolidMasse moléculaire :344.751,2-Bis(heptanoylthio)-sn-glycero-3-PG sodium
1,2-Bis(heptanoylthio)-sn-glycero-3-PG [1,2-Bis(heptanoylthio) glycerophosphatidylglycerol] sodium is a thioesterified phosphatidylglycerol derivative. It can be utilized to mimic phospholipase activity or serve as a probe molecule in membrane fusion studies.Couleur et forme :Odour SolidLEI110
CAS :LEI110 inhibits PLA2G16 and HRASLS enzymes, Ki 20 nM, selectively targets related thiol hydrolases.Formule :C25H23F3N2O3Degré de pureté :98.66% - 99.01%Couleur et forme :SolidMasse moléculaire :456.46PLA2-IN-1
PLA2-IN-1 (Compound 7) is a potent and selective inhibitor of phospholipase A (PLA2) with an IC50 value of 1 nM. It effectively inhibits PLA2-induced coagulation disorders in vitro and shows potential for use as an antidote for snake bites caused by cobra venom.Couleur et forme :Odour SolidVU533
CAS :VU533 is a NAPE-PLD activator, EC50=0.30 µM, boosts macrophage activity, potential in cardiometabolic diseases.Formule :C21H22FN3O3S2Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :447.55sPLA2 inhibitor 2
sPLA2 inhibitor 2 (compound 6a) is an sPLA2 inhibitor with an IC50 value of 0.0475 μM, making it valuable for diabetes research.Formule :C20H18N6O4S2Couleur et forme :SolidMasse moléculaire :470.521-Myristoyl-2-Linoleoyl-sn-glycero-3-PC
CAS :1-Myristoyl-2-Linoleoyl-sn-glycero-3-PC is a phospholipid identified in human plasma, characterized by the presence of Myristic acid and Linoleic acid at the sn-1 and sn-2 positions, respectively.Formule :C40H76NO8PCouleur et forme :SolidMasse moléculaire :730.01A4333
A4333, a biotinylated derivative of A3373, selectively inhibits Phospholipase D1 (PLD1) while sparing PLD2.Degré de pureté :98%Couleur et forme :Odour SolidMelittin Acetate
Melittin Acetate, a PLA2 activator, enhances low-weight PLA2 activity but not high-weight PLA2.Formule :C133H233N39O33Degré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :2906.51A3373
CAS :A3373 is a novel inhibitor targeting both Phospholipase D1 (PLD1) and Phospholipase D2 (PLD2), demonstrating half maximal inhibitory concentrations (IC50) ofFormule :C17H9F7N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :390.26
