Microbiologie/Virologie

D-4-Hydroxyphenylglycine is key in making β-lactam antibiotics like Amoxicillin and Cefadroxil.

3'-Deoxy-3'-fluoroguanosine is a nucleoside phosphorylase inhibitor that inhibits RNA replication by binding replons.

Panidazole is an amoebicide.

5-Hydroxypyrazine-2-Carboxylic Acid is a metabolite of anti-tuberculosis drug pyrazinamide.

Propoxur (Standard) is the standard substance of Propoxur, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Propoxur (Propoxure) is an insecticide used to control cockroaches, flies, mosquitoes, and lawn and turf insects. Acute (short-term) exposure of humans to propoxur by ingestion leads to cholinesterase inhibition of red blood cells, with mild cholinergic symptoms including blurred vision, nausea, vomiting, sweating, and tachycardia; however, the effects are transient. Chronic (long-term) inhalation exposure has resulted in depressed cholinesterase levels, headaches, vomiting, and nausea in humans. Chronic ingestion studies in animals have reported depressed cholinesterase levels, depressed body weight, effects to the liver and bladder, and a slight increase in neuropathy. No information is available on the reproductive, developmental, or carcinogenic effects of propoxur in humans. Mixed results are available from cancer studies of propoxur in animals. EPA has not classified propoxur for carcinogenicity.

Cabenoside D, a triterpenoid glycoside from lichen, has anti-inflammatory properties and blocks TPA-induced EBV-EA in mice.

Triperiden: an anticholinergic, anti-Parkinson's drug; inhibits influenza by blocking haemagglutinin changes.

Albendazole sulfoxide D3 is deuterium-labeled Albendazole sulfoxide. Albendazole sulfoxide is a broad-spectrum anthelmintic.

5'-O-TBDMS-dG, a modified nucleoside, is utilized in the synthesis of deoxyribonucleic acid or nucleic acid.

DMT-dG(dmf) Phosphoramidite is a phosphinamide monomer employed for oligonucleotide synthesis.

Nucleoside Phosphoramidites; Ready for phosphorylation

Bismuth subcarbonate, a bismuth-based semiconductor, has antibacterial uses, gastric protection, and applications in sensors and photocatalysts.

Nucleoside Derivatives - LNA-related nucleosides; Nucleoside Phosphoramidites

Kanamycin sulfate (Standard) is the standard substance of Kanamycin sulfate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Kanamycin sulfate (Kanamycin monosulfate) is an aminoglycoside antibiotic that interferes with protein synthesis by binding to the 70S ribosomal subunit of bacteria. Kanamycin sulfate exhibits antimicrobial activity against both Gram-positive and Gram-negative bacteria, as well as mycoplasmas.

Praziquantel (Standard) is the standard substance of Praziquantel, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Praziquantel (Droncit) increases the permeability of the tegument of susceptible worms, resulting in an influx and increase in intra-tegumental calcium leading to rapid contractions and paralysis of the worm's musculature through a subsequent increase in levels of calcium in the sarcoplasmic reticulum. Praziquantel is a pyrazinoisoquinoline derivative with anthelminthic property. In addition, vacuolization of the tegumental syncytium and blebbing results in tegument disintegration, leads to antigen exposure and elicit host defense responses to the worm.

Sulopenem (CP-70429) is a gastrointestinally absorbed carbapenem antibiotic with broad-spectrum antibacterial activity, inhibiting both Gram-positive.

Antibacterial agent 18 is a multi-armed AIE molecule with antibacterial activity, inhibiting the growth of both Gram-positive and Gram-negative bacteria.

Temocillin disodium (BRL 17421 disodium) is a carbapenem antibiotic with antimicrobial activity and can be used to study urinary tract infections.

SMARt751 targets the transcriptional regulator VirS, inhibiting its ability to bind DNA, which in turn enhances the expression of the mymA operon and activates Ethionamide. This activation increases the antimicrobial efficacy of Ethionamide against Mycobacterium tuberculosis, and overcomes its resistance. Furthermore, SMARt751 augments Ethionamide's antibacterial activity in mouse models and reduces its effective dose. Additionally, SMARt751 can permeate the blood-brain barrier.

GCA-2 is a potent enantiomer of GCA, selectively and efficiently kills An. stephensi larvae, useful for dengue research.

Fludioxonil (Standard) is the standard substance of Fludioxonil, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Fludioxonil (CGA 173506), a phenylpyrrole fungicide, inhibits the growth of B. cinerea from strawberry and blackberry crops.

Teclozan: benzylamine antiprotozoal, combats G. intestinalis, disrupts phospholipid metabolism, halts arachidonic acid synthesis, used in protozoal research.

Sivelestat sodium (EI 546 sodium) is a human neutrophil elastase inhibitor used in research on acute lung injury/acute respiratory distress syndrome.

Uridine 5'-diphosphate sodium, P2Y6 agonist (EC50: 300 nM), P2Y14 antagonist (pEC50: 7.28).

Triclosan-methyl, derived from bactericidal triclosan, is used in toothpaste, shampoos, soaps, detergents, and cosmetics.

6-Chloro-7-deazapurine-2F-β-D-arabinofuranose is a Nucleoside - 7-deazapurine nucleoside, fluoronucleoside, halo nucleoside; Arabino-nucleoside.

Lincomycin (U-10149) is a antibiotic against most susceptible gram-positive and cell wall-less bacteria .

2'-O-MOE-rC is a Nucleoside Phosphoramidite; Nucleoside Derivative - 2'-Modified nucleoside.

Naphthoquine phosphate is an antimalarial compound that may affect viral entry and post-entry replication.

Cefalexin hydrochloride is a cephalosporin antibiotic.

2’-O-Me-C(Bz) Phosphoramidite is a modified phosphoramidite monomer, which can be used for the oligonucleotide synthesis.

2',3'-Dideoxyadenosine is an inhibitor of HIV replication with antiretroviral activity and antiviral efficacy [1].

EDTA disodium dihydrate chelates metals, inhibits proteases, and aids in protein purification; doesn't affect cellulase.

5’-O-DMT-3’-O-TBDMS-Ac-rC is a modified nucleoside and can be used to synthesize DNA or RNA.

Bixafen is a succinate dehydrogenase inhibitor with hepatotoxicity, pancreotoxicity, and fungicidal activity, used for controlling crop diseases.

Aviptadil (INN) is an analog of vasoactive intestinal polypeptide (VIP) for the treatment of erectile dysfunction.

Albendazole-d3, a deuterated compound of Albendazole, is an anthelmintic and can be used to study the metabolism of Albendazole in vivo.

Sulbactam pivoxil is a prodrug of sulbactam, exhibiting oral bioavailability and superior absorption. Sulbactam functions as a β-lactamase inhibitor.

Triclopyr (NSC 190671) is a synthetic growth hormone-like herbicide and fungicide with cytotoxicity and mitochondrial damage induced in rat liver

Sulfamonomethoxine D4: deuterium-labeled, long-acting antibacterial sulfonamide; blocks folic acid synthesis in blood kinetics.

Nucleoside Derivatives - LNA-related nucleosides; Nucleoside Phorphoramidites

Etzadroxil, a volatile ester, treats drug-resistant urinary infections.

Carindacillin sodium, orally active broad-spectrum antibiotic, hydrolyzes to Carbenicillin, used in urinary tract infection studies.

Tomeglovir is a potent anti-CMV agent, inhibiting the processing of viral DNA-concatemers (IC50s: 0.34/0.039 μM for HCMV and MCMV).

Lanoconazole is an antifungal imidazole that is potent and orally available and acts by inhibiting the synthesis of ergosterol in fungal cell membranes.

Terizidone is a derivate of cycloserine with bacteriostatic activity.

Diethylcarbamazine citrate treats filariasis, targeting Loa loa and Wucheria bancrofti.

Balapiravir (R1626) is a prodrug targeting HCV polymerase, discontinued due to safety concerns like lymphopenia and other serious side effects.

Metalaxyl (CGA 48988) is a fungicide that inhibits protein synthesis in fungi and interferes with skeletal development in zebrafish embryos.

Diamfenetide is used in sheep and cattle for the treatment of liver fluxobacteria infections.

Oxacillin sodium monohydrate (Stapenor monohydrate) is an antibacterial agent and is a narrow spectrum beta-lactam antibiotic of the penicillin class.

Sulfaclozine sodium: antibacterial, anticoccidial sulphonamide for poultry disease treatment.

Acridine-9-carboxaldehyde is an acridine derivative that functions as a pH indicator for fluorescence lifetime measurements.

Niclofolan, a biphenyl anthelmintic compound, is used orally towards the treatment of Fasciola hepatica infection.

5'-DMTr-dC (Ac)-methylphosphonamidite is a Nucleoside Derivative - phosphonamidite.

Sulfadimethoxine D4 is a deuterium labeled Sulfadimethoxine (Sulphadimethoxine). Sulfadimethoxine is a sulfonamide antibiotic used to treat many infections.

3-oxo-C14-HSL is a quorum sensing signal that regulates genes and metabolism in bacteria, affecting biofilm and putisolvin production.

PD 404182 is a DDAH1 inhibitor with antiangiogenic and antiviral activities that can be used to study cardiovascular disease and viral infections.

2-Nitrobenzaldehyde Semicarbazone, a Semicarbazide derivative, detects antibiotic Nitrofurazone use.

Anguizole, a small molecule, effectively inhibits Hepatitis C Virus (HCV) replication by modifying the subcellular distribution of NS4B.

5'-O-DMTr-N6-Fmoc-dA-phosphoramidite is a Nucleoside Phosphoramidite.

Cefepime (BMY-28142) is a cephalosporin antibiotic with antimicrobial activity that induces neurotoxicity and can be used in the study of anaerobic bacteria.

2'-O-MOE-5MeU-3'-phosphoramidite is a Nucleoside Phosphoramidite.

2'-MOE-G(iBu)-3'-phosphoramidite is a Nucleoside Phosphoramidite;Nucleoside Derivative - 2'-Modified nucleoside;.

Diethylamine NONOate diethylammonium salt (DEA NONOate diethylamine) is a nitric oxide donor with antibacterial activity and inhibits the growth of E. coli.

1-(2'-O-4-C-Methylene-beta-D-ribofuranosyl)thymine is a bicyclic nucleoside.

Amorolfine HCL is an antifungal reagent.

9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate.

T.cruzi-IN-1 (MDK1088) is a Trypanosoma cruzi inhibitor.

Hydroxymetronidazole (Metronidazole-OH) is a nitroimidazole compound and metabolite of Metronidazole, commonly used in poultry research for bacterial and protozoal diseases, and in studies of swine dysentery and genital trichomoniasis in cattle.

X5050 is a REST inhibitor, with an EC 50 of 2.1 μM.

Acetyllovastatin inhibits acetylcholinesterase (IC50: 79 μg/mL), has antifungal properties, and hinders cancer cell growth.

5'-O-DMT-N2-ibu-dG is a deoxynucleoside served as a building block in oligonucleotide synthesis, with protecting groups to prevent unwanted reactions.

Tirilazad: a 21-aminosteroid preventing lipid peroxidation; aids in neuroprotection and treats ischemic conditions.

Nitazoxanide D4 is the deuterium labeled Nitazoxanide.

Sulfathiazole-d4 is a deuterated isotope of Sulfathiazole for isotope tracing. Sulfathiazole is a short-acting sulfonamide antibiotic.

2-Chloroacetamide: a preservative, herbicide, and biocide used in agriculture, glues, paints, with inhibitory effects on fatty acid elongase.

Cefozopran hydrochloride (SCE-2787 hydrochloride) is a fourth-generation cephalosporin.

EDTA copper(II) disodium salt is a metal chelator with antimicrobial, anti-inflammatory, and antioxidant activities for the study of neurological disorders.

Avibactam tomilopil (AV-006) is an oral prodrug of Avibactam, inhibiting class A and C β-lactamases, including ESBLs, AmpC, and KPC, antibacterial.

N6-Methyl-dA phosphoramidite can be used in the synthesis of oligodeoxyribonucleotides.

(±)-BI-D is an effective ALLINI(An allosteric IN inhibitor) that binds integrase at the LEDGF/p75 binding site (IC50: 2.4–2.9 μM).

Methyl α-D-mannopyranoside (Methyl α-D-mannopyranoside) can be used as an intermediate for chemical sythesis and can target macrophages in anti-

Flucloxacillin sodium (floxacillin sodium) is a highly active antibiotic against Gram-negative and Gram-positive bacteria.

IMP-1088 is a potent inhibitor of human N-myristoyltransferases NMT1 and NMT2 dual.

Inarigivir ammonium, an antiviral dinucleotide, lowers HBV DNA and activates innate immunity via RIG-I agonism.

Phosalone is an organophosphate chemical commonly used as an insecticide and acaricide.

Benzyldodecyldimethylammonium chloride dihydrate: a QAC biocide against MRSA, MDR P. aeruginosa.

Methenamine Hippurate is a component of Hiprex, with antibacterial activity.

Fluensulfone (MCW-2) is a low-toxicity, eco-friendly nematicide from the fluoroalkenyl thioether group.

Urolithin A is a metabolite of ellagic acid, which inhibits DNA synthesis and induces apoptosis and autophagy. Cost-effective and quality-assured.