Microbiologie/Virologie
Les inhibiteurs en microbiologie et virologie sont des composés qui ciblent les microorganismes, y compris les bactéries, les virus et les champignons, perturbant leur croissance, leur réplication ou leur survie. Ces inhibiteurs sont essentiels pour étudier la pathogénie microbienne, comprendre les mécanismes de résistance et développer de nouvelles thérapies antimicrobiennes et antivirales. Les inhibiteurs de cette catégorie sont utilisés pour combattre les maladies infectieuses, explorer l'écologie microbienne et étudier les interactions hôte-pathogène. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en microbiologie et virologie pour soutenir vos recherches en maladies infectieuses, microbiologie et virologie.
Sous-catégories appartenant à la catégorie "Microbiologie/Virologie"
- Antibactérien(2.957 produits)
- Antibiotique(920 produits)
- Antifection(23 produits)
- DHFR(33 produits)
- Synthèse ADN/ARN(708 produits)
- VHB(176 produits)
- Protéase du VIH(449 produits)
- HSV(91 produits)
- Intégrase(2 produits)
- Ribosome(13 produits)
Affichez 2 plus de sous-catégories
5842 produits trouvés pour "Microbiologie/Virologie"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
Isopyrazam
CAS :Isopyrazam, a plant protection product, exhibits potent antifungal activity. When applied to crops, it effectively inhibits the growth of various plant pathogenic fungi, significantly enhancing both the yield and quality of the crops. This compound demonstrates exceptional disease resistance capabilities in agricultural applications.Formule :C20H23F2N3OCouleur et forme :SolidMasse moléculaire :359.41Integrase-LEDGF/p75 allosteric inhibitor 1
CAS :<p>Oral HIV-1 allosteric integrase inhibitor, blocks DNA integration, antiviral, potent against NL432 (EC50: 3.9 nM).</p>Formule :C33H41NO6SCouleur et forme :SolidMasse moléculaire :579.75Epolactaene
CAS :<p>Epolactaene: neuritogenic, inhibits mammalian DNA polymerases & human DNA topoisomerase II.</p>Formule :C21H27NO6Couleur et forme :SolidMasse moléculaire :389.44iPAF1C
CAS :<p>iPAF1C is a powerful inhibitor of the polymerase-associated factor 1 complex (PAF1C) and exhibits anti-HIV activity [1].</p>Formule :C27H26BrFN4OCouleur et forme :SolidMasse moléculaire :521.42Enantiomer of Sofosbuvir
<p>Inactive enantiomer of Sofosbuvir, used for chronic hepatitis C; lacks reported biological activity.</p>Formule :C22H29FN3O9PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :529.45MTH1 activator-1
CAS :<p>MTH1 activator-1 is an MTH1 activator that enhances endogenous MTH1 activity and significantly reduces 8-oxo-dG levels in cellular DNA. It is useful for investigating the upregulation of oxidative damage repair in nucleotide pools and examining biological effects, as well as for studies aiming to delay or prevent tumorigenesis.</p>Formule :C29H23F3N4O2Couleur et forme :SolidMasse moléculaire :516.514Antifungal agent 11
<p>Antifungal agent 11 has a good antifungal effect.</p>Formule :C21H19F2N7O3S2Couleur et forme :SolidMasse moléculaire :519.55AAA-10 formic
<p>AAA-10 formic is an orally active inhibitor of intestinal bacterial bile salt hydrolase (BSH) against B.</p>Formule :C26H43FO7SCouleur et forme :SolidMasse moléculaire :518.68ALG-000184
CAS :<p>ALG-000184, a prodrug of the potent HBV capsid assembly modulator ALG-001075, shows potential for use in HBV infection research.</p>Formule :C23H20FN4Na2O8PCouleur et forme :SolidMasse moléculaire :576.379SARS-CoV-IN-6
CAS :<p>SARS-CoV-IN-6 (Compound 17) acts as an inhibitor of SARS-CoV-1 and SARS-CoV-2 RdRp, demonstrating an IC50 value of 7.8 μM against SARS-CoV-2 RdRp. This compound reduces the cytopathic effects of single-round infectious particles (SRIP) infected with SARS-CoV-1 and SARS-CoV-2 replicons and inhibits the expression of SARS-CoVN proteins. The EC50 values for SRIP based on SARS-CoV-1 and SARS-CoV-2 replicons are 0.12 µM and 1.47 µM, respectively.</p>Formule :C25H29N5O3Couleur et forme :SolidMasse moléculaire :447.53Finafloxacin
CAS :<p>Finafloxacin is a pH-activated fluoroquinolone, most effective at pH 5.0-6.0, targeting bacterial topoisomerases, used for UTIs and H. pylori infections.</p>Formule :C20H19FN4O4Couleur et forme :SolidMasse moléculaire :398.39PqsR-IN-2
<p>PqsR-IN-2, potent PqsR inhibitor, curbs Pseudomonas aeruginosa communication, reduces pyocyanin, with low toxicity.</p>Formule :C18H20ClN3OSCouleur et forme :SolidMasse moléculaire :361.89Antiviral agent 15
<p>Compound 15f, a Clofazimine derivative, inhibits rabies (EC50: 1.45 μM) and SARS-CoV-2 (EC50: 14.6 μM).</p>Formule :C27H24FN5OCouleur et forme :SolidMasse moléculaire :453.51HIV-1 inhibitor-14
<p>HIV-1 inhibitor-14: potent, broad HIV-1 RT inhibitor. IC50=0.14μM. Effective against wild-type and resistant strains, EC50=5.79-28.3nM.</p>Formule :C29H32N6O4SCouleur et forme :SolidMasse moléculaire :560.67Antitubercular agent-29
<p>Compound 6xa inhibits drug-resistant tuberculosis with MICs 0.03 μg/mL for DS-Mtb and 0.03-0.06 for DR-Mtb, SI>40 for Vero cells.</p>Formule :C20H12ClN3O5Couleur et forme :SolidMasse moléculaire :409.78Antibacterial agent 99
CAS :<p>Compound 7b (Antibacterial agent 99) is an effective agent with antibacterial, antifungal properties and no haemolytic activity.</p>Formule :C27H27BrN2Couleur et forme :SolidMasse moléculaire :459.42EBOV-GP-IN-1
<p>EBOV-GP-IN-1 (Compound 28) is a potent inhibitor of Ebola entry, acting on the Ebola virus envelope glycoprotein (EBOV-GP) (IC50: 0.05 μM).</p>Formule :C25H40ClN3O2Couleur et forme :SolidMasse moléculaire :450.06Triazophos
CAS :<p>Triazophos is a non-systemic pesticide that acts as an acetylcholinesterase (AChE) inhibitor, forming a covalent and irreversible bond with the acetylcholine binding site. This action blocks the hydrolysis of acetylcholine, leading to increased excitability. It is effective against a wide range of soil insects and mites, including aphids, thrips, midges, beetles, lepidopteran larvae, mole crickets, and red spiders. Triazophos is suitable for use on various crops such as ornamental plants, cotton, rice, corn, soybeans, oil palm, olives, and coffee.</p>Formule :C12H16N3O3PSCouleur et forme :SolidMasse moléculaire :313.31SARS-CoV-2-IN-8
<p>SARS-CoV-2-IN-8 is a major protease inhibitor of SARS-CoV-2 (IC50: 0.75 μM).</p>Formule :C35H38N6O3Couleur et forme :SolidMasse moléculaire :590.71Elongation factor P-IN-2
<p>Elongation factor P-IN-2, a β-lysine derivative, is a potent EFP inhibitor reducing E. coli growth.</p>Formule :C16H35N3O2Couleur et forme :SolidMasse moléculaire :301.47DENV-IN-6
CAS :<p>DENV-IN-6, a potent anti-DENV (I-IV) and HIV-1 IIIB inhibitor with EC50 ranging 6.8-17.5 μM for DENV and EC50 0.0181 μM for HIV-1.</p>Formule :C23H26ClFN4OSCouleur et forme :SolidMasse moléculaire :461GSK3739936
CAS :<p>GSK3739936 inhibits HIV-1 integrase (IC50: 11.1 nM, EC50: 1.7 nM), weak on CYP (IC50 >24.3 μM), rapid absorption, moderate clearance, high oral availability.</p>Formule :C34H43FN2O4Couleur et forme :SolidMasse moléculaire :562.71CB 30900
CAS :<p>CB30900 is a novel and effective thymidylate synthase inhibitor.</p>Formule :C31H32FN5O9Couleur et forme :SolidMasse moléculaire :637.61SMCypI C31
<p>SMCypIC31, a non-peptide cyclophilin inhibitor, blocks PPIase at 0.1 μM IC50 and fights various HCV genotypes (EC50: 1.20-7.76 μM).</p>Formule :C27H30N4O2SCouleur et forme :SolidMasse moléculaire :474.62CYP2C19-IN-1
<p>CYP2C19-IN-1: potent CYP2C19 inhibitor, non-genotoxic, non-hepatotoxic, blocks RdRP (Ki: 6.16 μM), useful for ZIKV research.</p>Formule :C26H26N2O6SCouleur et forme :SolidMasse moléculaire :494.56Avibactam sodium dihydrate
<p>Avibactam sodium dihydrate (NXL-104) is a reversible covalent inhibitor for CTX-M-15 and TEM-1 β-lactamases with IC50s of 5 nM and 8 nM.</p>Formule :C7H14N3NaO8SCouleur et forme :SolidMasse moléculaire :323.26Antifungal agent 27
<p>Antifungal agent 27 shows moderate action against MRSA, weak against C. albicans, with MICs of 8 μg/mL and 32 μg/mL, respectively.</p>Formule :C18H23N5OSCouleur et forme :SolidMasse moléculaire :357.47Antibacterial agent 88
<p>Antibacterial agent 88 is an effective antibacterial agent against B. subtilis (MIC: 4 μg/ml) with MIC values of ≤0.0156 μg/mL for MRSA, MRSE and S. aureus.</p>Formule :C31H44N2O6SCouleur et forme :SolidMasse moléculaire :572.76E6-272
CAS :<p>E6-272, an inhibitor of HPV 16, induced early and late apoptosis in HPV16-positive cervical cancer cells and inhibited the proliferation of SiHa and CaSki.</p>Formule :C26H28N2ODegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :384.51Antifungal agent 43
<p>Antifungal agent 43 inhibits biofilms with low toxicity to human cancer cells.</p>Formule :C24H26N4Se2Couleur et forme :SolidMasse moléculaire :528.41Streptothricin F
CAS :<p>Streptothricin F is a biochemical.</p>Formule :C19H34N8O8Couleur et forme :SolidMasse moléculaire :502.52Xanthosine-5'-Triphosphate trisodium
CAS :<p>Xanthosine-5'-Triphosphate (5'-XTP) trisodium is a nucleotide formed through the deamination of purine bases. It serves as a substrate for inosine triphosphate pyrophosphatase (ITPase).</p>Formule :C10H12N4Na3O15P3Couleur et forme :SolidMasse moléculaire :590.1115-Methylcytosine hydrochloride
CAS :<p>5-Methylcytosine hydrochloride plays a critical role in regulating gene expression, promoting genomic imprinting, and inhibiting transposon factors. It is also closely associated with translation fidelity and tRNA recognition.</p>Formule :C5H8ClN3OCouleur et forme :SolidMasse moléculaire :161.59MIV-150
CAS :<p>MIV-150 is a nonnucleoside inhibitor of reverse transcriptase (NNRT). MIV-150 also blocking HIV-1 and HIV-2 infections (EC50<1 nM against HIV-1/HIV-2MN).</p>Formule :C19H17FN4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :368.36NRTT-IN-1
CAS :<p>NRTT-IN-1 (Compound 1) is an inhibitor of the nucleoside reverse transcriptase translocation (NRTT), effectively blocking HIV DNA synthesis and viral replication.</p>Formule :C28H24FN5O5Couleur et forme :SolidMasse moléculaire :529.519Xeruborbactam isoboxil
CAS :<p>Xeruborbactam isoboxil is a β-lactamase (beta-lactamase) inhibitor.</p>Formule :C15H16BFO6Couleur et forme :SolidMasse moléculaire :322.093Cap-dependent endonuclease-IN-5
CAS :<p>Cap-dependent endonuclease-IN-5 inhibits CEN and fights influenza with low toxicity and good in vivo properties.</p>Formule :C27H21F2N3O4S2Couleur et forme :SolidMasse moléculaire :553.60Antitubercular agent-15
<p>Antitubercular agent-15 (5n): low toxicity, fights M. tuberculosis strains; MIC90 values range 0.73-18.8 μg/mL.</p>Formule :C21H29FN2Couleur et forme :SolidMasse moléculaire :328.47cis-RdRP-IN-5
<p>Cis-RdRP-IN-5 is an effective inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), employed in influenza virus research.</p>Formule :C23H21N3O5Couleur et forme :SolidMasse moléculaire :419.43Antifungal agent 17
<p>Antifungal agent 17 showed good antifungal activity against B. cinerea (EC50: 2.86 μg/mL).</p>Formule :C18H16Br2O2Couleur et forme :SolidMasse moléculaire :424.13UMPK ligand 1
CAS :<p>UMPK ligand 1 (ZINC07785412) serves as a ligand for uridine monophosphate kinase (UMPK).</p>Formule :C15H22N4O5SCouleur et forme :SolidMasse moléculaire :370.424SARS 3CLpro-IN-1
CAS :<p>SARS 3CLpro-IN-1: stereospecific SARS 3CL protease inhibitor, octahydroisochromene class, IC50 = 95 μM.</p>Formule :C22H38N4O2Couleur et forme :SolidMasse moléculaire :390.56RmlA-IN-2
<p>RmlA-IN-2: Strong RmlA blocker, hinders l-rhamnose synthesis & alters bacterial wall permeability (IC50: 0.303 μM).</p>Formule :C22H26BrN5O4SCouleur et forme :SolidMasse moléculaire :536.44NS2B/NS3-IN-3
CAS :<p>NS2B/NS3-IN-3 (Compd 66) is an inhibitor of Flavivirus NS2B-NS3 protease [1] .</p>Formule :C19H21N3O2Couleur et forme :SolidMasse moléculaire :323.39Acetomycin
CAS :<p>Acetomycin, a γ-lactone from S. ramulosus, halts HCT-8 colon and L1210 leukemia cell growth.</p>Formule :C10H14O5Couleur et forme :SolidMasse moléculaire :214.22SP inhibitor 1
<p>SP inhibitor 1 blocks SARS-CoV-2 replication in vitro (0.3250<5.98 μM) and targets SP protein (IC50: 3.26 μM) with antiviral effects.</p>Formule :C36H38N2O2Couleur et forme :SolidMasse moléculaire :530.7LasR-IN-3
<p>LasR-IN-3 inhibits LasR in Pseudomonas, disrupting its dimer, causing loss of function.</p>Formule :C22H19N3O2Couleur et forme :SolidMasse moléculaire :357.41Anthelvencin A
CAS :<p>Anthelvencin A is a pyrrolylamide metabolite with moderate antibacterial and anthelmintic activity.</p>Formule :C19H25N9O3Couleur et forme :SolidMasse moléculaire :427.46(R)-CSN5i-3
CAS :<p>(R)-CSN5i-3 is CSN5i-3 of the R configuration.</p>Formule :C28H29F2N5O2Degré de pureté :99.76% - 99.97%Couleur et forme :SolidMasse moléculaire :505.56TREX1-IN-4
CAS :<p>TREX1-IN-4 (Compound 96) is an inhibitor of TREX1 and TREX2, exhibiting an IC50 of less than 0.1 μM for TREX1 and an IC50 of less than 1 μM for TREX2. It has an EC50 ranging from 0.1 to 10 μM in HCT116 cells. TREX1-IN-4 is applicable for research in the field of cancer.</p>Formule :C24H19ClN6O4Couleur et forme :SolidMasse moléculaire :490.898Ganaplacide hydrochloride
CAS :<p>Ganaplacide hydrochloride (KAF156 HCl) is an orally administered imidazopyrimidine antimalarial agent that inhibits Plasmodium PI4K activity.</p>Formule :C22H24ClF2N5ODegré de pureté :93.97%Couleur et forme :SoildMasse moléculaire :447.91SARS-CoV-2 Mpro-IN-44
CAS :<p>SARS-CoV-2 Mpro-IN-44 (Compound 25) is a broad-spectrum inhibitor of the main protease (Mpro) for coronaviruses. It exhibits inhibitory activity against several high-risk coronaviruses, including SARS-CoV-2 and PEDV, with an IC50 of less than 0.6 μM. The broad inhibition of coronaviruses by SARS-CoV-2 Mpro-IN-44 is achieved through enhanced interaction with conserved sites of Mpro. This compound is a potential candidate for the development of antiviral drugs against coronaviruses.</p>Formule :C29H19Cl2FN8O4SCouleur et forme :SolidMasse moléculaire :665.48Omaciclovir
CAS :<p>Omaciclovir (ABT-091) is a herpesvirus herpesvirus replication inhibitor with antiviral activity that is used in the study of herpesvirus infections.</p>Formule :C10H15N5O3Degré de pureté :99.46% - 99.46%Couleur et forme :SolidMasse moléculaire :253.26APE1-IN-3
CAS :<p>APE1-IN-3 (Compound 1), an APE1 inhibitor, is utilized in cancer research.</p>Formule :C17H16O4Couleur et forme :SolidMasse moléculaire :284.312-Acetyl-2-decarboxamidotetracycline
CAS :<p>2-Acetyl-2-decarboxamidotetracycline is a tetracycline-class antibiotic. It exhibits a UV absorption spectrum similar to that of tetracycline or 5-oxytetracycline at concentrations above 300 mμ, characteristic of the BCD ring system.</p>Formule :C23H25NO8Couleur et forme :SolidMasse moléculaire :443.45GTSE1-IN-1
CAS :<p>GTSE1-IN-1 (compound Y18), an orally active GTSE1 inhibitor, exhibits notable anticancer properties. It effectively represses the proliferation of cancer cells by downregulating GTSE1 transcription and expression, which leads to DNA damage and promotes persistent cell cycle arrest and cellular senescence. Moreover, GTSE1-IN-1 substantially reduces the adhesion, migration, and invasion of colorectal cancer HCT116 cells and non-small cell lung cancer A549 cells in vitro.</p>Formule :C21H24FN7Couleur et forme :SolidMasse moléculaire :393.4620S Proteasome-IN-4
CAS :<p>20S Proteasome-IN-4: brain-penetrant, parasite-specific, oral, inhibits T.b. brucei proteasome (IC50: 6.3nM), for HAT research.</p>Formule :C20H18ClF2N3O3Couleur et forme :SolidMasse moléculaire :421.8317,17-Ethylendioxyandrost-5-en-3β-ol
CAS :<p>17,17-Ethylendioxyandrost-5-en-3β-ol, with an EC 50 of 629 μM, acts as an inhibitor of HSV-1. This compound is applicable in research studies focusing on viral infections.</p>Formule :C21H32O3Couleur et forme :SolidMasse moléculaire :332.48bc1 Complex-IN-1
CAS :<p>Bc1 Complex-IN-1 (compound 12g) is a potent inhibitor of the bc1 complex, demonstrating fungicidal properties against cucumber downy mildew (CDM).</p>Formule :C16H22N6O5S2Couleur et forme :SolidMasse moléculaire :442.513HBV-IN-48
CAS :<p>HBV-IN-48, an HBV inhibitor, exhibits potent antiviral activity against HBV in HepDE19 cells, demonstrated by its EC 50 value of 0.005 μM. Additionally, it effectively reduces serum HBV DNA levels in mouse models of HBV infection.</p>Formule :C22H15F4N3O3Couleur et forme :SolidMasse moléculaire :445.37GSK_WRN4
CAS :<p>GSK_WRN4 is a WRN helicase inhibitor with anti-cancer activity, inhibiting MSI tumor cell growth by inducing DNA double-strand breaks, useful in cancer research</p>Formule :C16H20N2O4SDegré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :336.41MB076
CAS :MB076 is an innovative heterocyclic triazole designed with enhanced plasma stability. It effectively inhibits seven distinct Class C Acinetobacter-derived cephalosporinases (ADCs) β-lactamase variants with K i values less than 1 μM. Additionally, MB076 demonstrates a synergistic effect when combined with various cephalosporins to restore pBCSK(−) susceptibility [1].Formule :C9H12BN7O5S2Masse moléculaire :373.18Ibafloxacine
CAS :<p>Ibafloxacine (R835) is a fluoroquinolone antibiotic that is used exclusively in veterinary applications and shows zero good bacteriostatic effect against</p>Formule :C15H14FNO3Degré de pureté :97.67%Couleur et forme :SolidMasse moléculaire :275.27NS2B/NS3-IN-4
CAS :<p>Compound 34e inhibits DENV2/ZIKV proteases; IC50: 0.69 µM (DENV2), 1.04 µM (ZIKV).</p>Formule :C15H11NO4Couleur et forme :SolidMasse moléculaire :269.25SPB07935
CAS :<p>SPB07935 inhibits plasmepsin II in the malaria-causing parasite Plasmodium falciparum and serves as an antimalarial agent. It affects the life cycle of P. falciparum, hindering the growth of the parasite's FcB1 and 3D7 strains, with IC50 values of 8 μM and 4.7 μM, respectively.</p>Formule :C22H15N5O4S2Couleur et forme :SolidMasse moléculaire :477.516QPX7728 methoxy acetoxy methy ester
CAS :<p>QPX7728 methoxy acetoxy methy ester is an inhibitor of boronic acid β-lactamase.</p>Formule :C14H14BFO7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :324.07PLpro-IN-6
CAS :<p>PLpro-IN-6 (compound 6) serves as an inhibitor for the papain-like protease (PLpro), demonstrating potent activity with an IC 50 of 0.019 μM against the SARS-CoV-2 PLpro enzyme.</p>Formule :C29H30N6OCouleur et forme :SolidMasse moléculaire :478.59DNDI-8219
CAS :<p>DNDI-8219 is an antitubercular agent. It has potent antileishmanial effects.</p>Formule :C13H10F3N3O5Couleur et forme :SolidMasse moléculaire :345.23HPH-15
CAS :<p>HPH-15 is an anti-cell migration compound that inhibits cell movement by binding to hnRNP U or suppressing TGF-β. Additionally, it prevents epithelial-to-mesenchymal transition (EMT). HPH-15 holds potential for research in areas such as anti-tumor metastasis and anti-fibrosis.</p>Formule :C19H31N3S4Couleur et forme :SolidMasse moléculaire :429.73GC373
CAS :<p>GC373, an effective inhibitor of the SARS-CoV-2 M pro, impedes virus replication, exhibiting an inhibition concentration (IC 50) of 0.4 μM. This compound is valuable for use in anti-COVID-19 research.</p>Formule :C21H29N3O5Couleur et forme :SolidMasse moléculaire :403.47TREX1-IN-3
CAS :<p>TREX1-IN-3 (Compound 95) is an inhibitor of TREX1 and TREX2, with an IC50 of less than 0.1 μM for TREX1 and less than 1 μM for TREX2, as well as an EC50 of less than 1 μM for HCT116 cells. It is applicable for research in the field of cancer.</p>Formule :C24H19ClN6O4Couleur et forme :SolidMasse moléculaire :490.898Eravacycline
CAS :<p>Eravacycline (TP-434) is a potent and broad-spectrum antibacterial agent.</p>Formule :C27H31FN4O8Degré de pureté :97.46%Couleur et forme :SolidMasse moléculaire :558.56LN002
CAS :<p>LN002 is an orally active inhibitor of Cryptosporidium oxidase, utilized for research in cryptosporidiosis.</p>Formule :C22H15N7Couleur et forme :SolidMasse moléculaire :377.40Aurachin C
CAS :<p>Aurachin C is a quinoline alkaloid belonging to the isoprenoid class, known for its antimalarial, antifungal, and antibacterial properties. It acts as a selective terminal oxidase inhibitor.</p>Formule :C25H33NO2Couleur et forme :SolidMasse moléculaire :379.535NDM-1 inhibitor-7
CAS :<p>NDM-1 inhibitor-7 (Compound A8) is an NDM-1 inhibitor with an IC50 of 10.284 μM. It restores the ability of meropenem (MEM) to penetrate the cell wall of Gram-negative bacteria and effectively reinstates MEM's antibacterial activity against NDM-1 positive Escherichia coli. Moreover, NDM-1 inhibitor-7 demonstrates significant efficacy in both Galleria mellonella and murine peritonitis infection models.</p>Formule :C9H10N2OS2Couleur et forme :SolidMasse moléculaire :226.319KWR095
CAS :<p>KWR095 is an orally active inhibitor of WRN, demonstrating an IC50 of 0.032 μM against WRN ATPase. It disrupts the double-stranded helicase activity of WRN and inhibits tumor cell proliferation, exhibiting antitumor properties.</p>Formule :C33H31ClF3N9O4Couleur et forme :SolidMasse moléculaire :710.105Anti-Trypanosoma cruzi agent-2
<p>Compd 3b: anti-trypanosomal, IC50 0.51 μM (NINOA), 3.06 μM (INC-5), also combats T. gondii.</p>Formule :C17H10ClNO5Couleur et forme :SolidMasse moléculaire :343.72Antitrypanosomal agent 5
<p>Antitrypanosal agent 5 is a selective anti-trypanosomal agent that acts on T. brucei (IC50: 1 nM) and HEK293 cells (IC50: 483.3 μM).</p>Formule :C30H30N6O4SCouleur et forme :SolidMasse moléculaire :570.66Neocryptolepine-Cl
CAS :<p>Neocryptolepine-Cl (compound Z24) is an inhibitor of Bcthi4, demonstrating excellent antifungal activity against B. cinerea, with an EC50 value of 0.56 μg/mL.</p>Formule :C16H11ClN2Couleur et forme :SolidMasse moléculaire :266.725ONO-5334
CAS :<p>ONO-5334: selective cathepsin K inhibitor, potential for osteoporosis study; Ki: 0.10 nM (human), 0.049 nM (rabbit), 0.85 nM (rat).</p>Formule :C21H34N4O4SDegré de pureté :98.22% - 99.60%Couleur et forme :SolidMasse moléculaire :438.58Antibacterial agent 62
<p>Novel anti-TB agent 62 is a redox compound with bactericidal activity against active and dormant bacteria.</p>Formule :C24H33BrN2O2Couleur et forme :SolidMasse moléculaire :461.44Urease-IN-2
<p>Urease-IN-2 is a non-competitive inhibitor of urease (IC50: 0.94 μM, Ki: 1.6 μM) that non-competitively inhibits Jack bean urease (JBU).</p>Formule :C26H25N5O5S3Couleur et forme :SolidMasse moléculaire :583.7HCV-IN-38
<p>Potent oral HCV inhibitor HCV-IN-38 has 15 nM EC50, 431 SI, high efficacy, and low toxicity.</p>Formule :C22H24ClF3N4O4Couleur et forme :SolidMasse moléculaire :500.9XR8-69
<p>XR8-69 is a SARS-CoV-2 PLpro inhibitor. XR8-69 has a low micromolar antiviral effect in SARS-CoV-2 infected human cells.</p>Formule :C26H30N4O2SCouleur et forme :SolidMasse moléculaire :462.61HCV-IN-7
CAS :<p>HCV-IN-7: potent oral HCV NS5A inhibitor, pan-genotypic, IC50s 3-47 pM, good pharmacokinetics, favorable liver uptake.</p>Formule :C40H48N8O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :768.92Cap-dependent endonuclease-IN-17
CAS :<p>CEN inhibitor IN-17 targets influenza A/H3N2; IC50: 1.29 μM. From patent CN112898346A, DSC701.</p>Formule :C24H20F2N3O7PSCouleur et forme :SolidMasse moléculaire :563.47Xeruborbactam
CAS :<p>QPX7728 is an of ultra-broad-spectrum boronic acid beta-lactamase.</p>Formule :C10H8BFO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :221.98SPR7
<p>SPR7 is a potent and selective rhodesain inhibitor (Ki: 0.51 nM). SPR7 exhibited antiparasitic effects against T. b. brucei (EC50: 1.65 μM).</p>Formule :C30H32ClN3O3Couleur et forme :SolidMasse moléculaire :518.05Cefoxazole
CAS :<p>Cefoxazole is a β-lactam antibiotic featuring an isoxazole structure, known for its antibacterial activity. It can be utilized in the study of infectious diseases.</p>Formule :C21H18ClN3O7SCouleur et forme :SolidMasse moléculaire :491.902Imidocarb dihydrochloride monohydrate
<p>Imidocarb dihydrochloride monohydrate is an effective antiprotozoal agent against the parasite B. bovis (IC50: 87 μg/ml).</p>Formule :C19H24Cl2N6O2Couleur et forme :SolidMasse moléculaire :439.34Telinavir
CAS :<p>Telinavir (SC-52151) is a potent and selective inhibitor of HIV protease. It effectively inhibits both HIV-1 and HIV-2, as well as lymphotropic, monocytotropic strains, and wild isolates of simian immunodeficiency viruses, with an EC50 of 26 ng/mL (43 nM). Telinavir shows high protein binding in human plasma and a low distribution rate in red blood cells.</p>Formule :C33H44N6O5Couleur et forme :SolidMasse moléculaire :604.74TLR8 agonist 4
<p>TLR8 agonist 4 inhibits wild-type and lamivudine/entecavir-resistant HBV; IC50: 0.15 μM and 0.10 μM.</p>Formule :C28H27N5O5SCouleur et forme :SolidMasse moléculaire :545.61SARS-CoV-2-IN-22
CAS :<p>SARS-CoV-2-IN-22 is a SARS-CoV-2 pseudovirus inhibitor (IC50: 16.96 μM).</p>Formule :C27H24N2O3SCouleur et forme :SolidMasse moléculaire :456.56Alpibectir
CAS :<p>Alpibectir has antibacterial activity [1].</p>Formule :C12H14F6N2O2Couleur et forme :SolidMasse moléculaire :332.24Piperacillin hydrate
CAS :<p>Piperacillin hydrate is a semisynthetic broad-spectrum β-lactam antibiotic. It exhibits potent bactericidal activity against Gram-negative bacteria and some Gram-positive bacteria by targeting penicillin-binding proteins. Piperacillin hydrate is frequently combined with the β-lactamase inhibitor Tazobactam for enhanced efficacy.</p>Formule :C23H29N5O8SCouleur et forme :SolidMasse moléculaire :535.57Antibacterial agent 279
CAS :<p>Antibacterialagent 279 (compound A12) is an effective antibacterial agent. It inhibits the SOS response of Pseudomonas aeruginosa.</p>Formule :C9H11NO2SCouleur et forme :SolidMasse moléculaire :197.25PCNA-IN-1
CAS :<p>PCNA-IN-1 (Compound 11) is an inhibitor of the PCNA/PIP-box interaction, with an IC50 greater than 50 μM. It is applicable in cancer research.</p>Formule :C19H18I3NO3Couleur et forme :SolidMasse moléculaire :689.065HIV-1 inhibitor-17
<p>HIV-1 inhibitor-18 blocks HIV-1 capsid, acts on NL4-3 strain (EC50: 2.57 μM), has low cytotoxicity (MT-4 CC50: >8.55).</p>Formule :C32H32N4O5SCouleur et forme :SolidMasse moléculaire :584.69Antifungal agent 12
<p>Antifungal agent 12 is a new fluconazole-like compound that exhibits good antifungal effects.</p>Formule :C20H16F3N7O2S2Couleur et forme :SolidMasse moléculaire :507.51Antibacterial agent 87
<p>Antibacterial agent 87 is an effective antibacterial agent that acts on MRSA (MIC: 0.125 μg/ml), MRSE (MIC: 0.0625 μg/ml) and S. aureus (MIC: 0.0625 μg/ml).</p>Formule :C31H46N2O6SCouleur et forme :SolidMasse moléculaire :574.77
