Microbiologie/Virologie
Les inhibiteurs en microbiologie et virologie sont des composés qui ciblent les microorganismes, y compris les bactéries, les virus et les champignons, perturbant leur croissance, leur réplication ou leur survie. Ces inhibiteurs sont essentiels pour étudier la pathogénie microbienne, comprendre les mécanismes de résistance et développer de nouvelles thérapies antimicrobiennes et antivirales. Les inhibiteurs de cette catégorie sont utilisés pour combattre les maladies infectieuses, explorer l'écologie microbienne et étudier les interactions hôte-pathogène. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en microbiologie et virologie pour soutenir vos recherches en maladies infectieuses, microbiologie et virologie.
Sous-catégories appartenant à la catégorie "Microbiologie/Virologie"
- Antibactérien(2.949 produits)
- Antibiotique(918 produits)
- Antifection(23 produits)
- DHFR(32 produits)
- Synthèse ADN/ARN(706 produits)
- VHB(176 produits)
- Protéase du VIH(447 produits)
- HSV(91 produits)
- Intégrase(2 produits)
- Ribosome(13 produits)
Affichez 2 plus de sous-catégories
5832 produits trouvés pour "Microbiologie/Virologie"
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Insecticidal agent 16
CAS :<p>Insecticidal agent 16 (compound A21) exhibits insecticidal activity against Plutella xylostella, with LC50 values of 1.2 and 13.2 µg/mL respectively.</p>Formule :C21H13Cl2F6N5O2SCouleur et forme :SolidMasse moléculaire :584.32SARS-CoV-2 Mpro-IN-32
CAS :<p>SARS-CoV-2 Mpro-IN-32 (Compound 1) is a selective inhibitor of SARS-CoV-2 MPro with an IC50 value of 230 nM. In vitro, it also inhibits the replication of various SARS-CoV-2 variants.</p>Formule :C34H32Cl2N4O9Couleur et forme :SolidMasse moléculaire :711.54NDM-1 inhibitor-3
<p>NDM-1 inhibitor-3 is a New Delhi Metallo-β-lactamase-1 (NDM-1) inhibitor (Ki : 4 μM) widely found in nature and is associated with antibiotic resistance.</p>Formule :C16H12O4Degré de pureté :98.66%Couleur et forme :SolidMasse moléculaire :268.26OPC-167832
CAS :<p>OPC-167832: oral dprE1 inhibitor, IC50 0.258 μM, anti-tuberculosis, for Mycobacterium tuberculosis research.</p>Formule :C21H20ClF3N2O4Couleur et forme :SolidMasse moléculaire :456.84SARS-CoV-2 Mpro-IN-31
CAS :<p>SARS-CoV-2 Mpro-IN-31 (Compound 18) is an inhibitor of SARS-CoV-2 MPro with an IC50 of 11 nM. Additionally, this compound effectively inhibits the enzymatic activity of the cysteine proteases cathepsin B and cathepsin L, with IC50 values of 24 nM and 1.8 nM, respectively.</p>Formule :C31H34Cl2N4O7Couleur et forme :SolidMasse moléculaire :645.53Valopicitabine dihydrochloride
CAS :<p>Valopicitabine, a NS5B inhibitor, is used potentially for the treatment of HCV infection.</p>Formule :C15H25ClN4O6Couleur et forme :SolidMasse moléculaire :392.84HIV-1 inhibitor-14
<p>HIV-1 inhibitor-14: potent, broad HIV-1 RT inhibitor. IC50=0.14μM. Effective against wild-type and resistant strains, EC50=5.79-28.3nM.</p>Formule :C29H32N6O4SCouleur et forme :SolidMasse moléculaire :560.67ZG297
CAS :<p>ZG297 is an agonist of Staphylococcus aureus ClpP (SaClpP) with an EC50 of 0.26 μM. It degrades SaFtsZ and inhibits bacterial cell division, exhibiting antistaphylococcal activity by inhibiting S. aureus 8325-4 and MRSA strains, with a MIC range of 0.063-256 μg/mL. In mouse models, ZG297 demonstrates anti-infective properties.</p>Formule :C31H35F3N4O3Couleur et forme :SolidMasse moléculaire :568.63Ibafloxacine
CAS :<p>Ibafloxacine (R835) is a fluoroquinolone antibiotic that is used exclusively in veterinary applications and shows zero good bacteriostatic effect against</p>Formule :C15H14FNO3Degré de pureté :97.67%Couleur et forme :SolidMasse moléculaire :275.27Antibacterial agent 174
CAS :<p>Compound 174 (Compound 5g), an antibacterial agent, exhibits potent anti-infective properties in vivo along with appreciable pharmacokinetic profiles. This highly active substance demonstrates favorable biofilm removal capabilities, low hemolysis, and acceptable mammalian cell toxicity [1].</p>Formule :C25H30FN2NaO5Couleur et forme :SolidMasse moléculaire :480.5Antibacterial agent 172
CAS :<p>Antibacterial Agent 172 (Compound 6a), a <i>Clostridioides difficile (Cd) SpoVD inhibitor with an IC50 value of 89 nM, effectively inhibits the sporulation of Clostridioides difficile. It is useful for research on bacterial infections [1].</p>Formule :C21H21N9O5S2Couleur et forme :SolidMasse moléculaire :543.58Antimicrobial agent-29
CAS :<p>Antimicrobial Agent-29 (Compound C35) influences the interaction between human hemoglobin and the Staphylococcus aureus IsdB hemophore. This compound facilitates the identification of IsdB:Hb PPI inhibitors [1].</p>Formule :C19H14N4O4SCouleur et forme :SolidMasse moléculaire :394.45-Methylcytosine hydrochloride
CAS :<p>5-Methylcytosine hydrochloride plays a critical role in regulating gene expression, promoting genomic imprinting, and inhibiting transposon factors. It is also closely associated with translation fidelity and tRNA recognition.</p>Formule :C5H8ClN3OCouleur et forme :SolidMasse moléculaire :161.59Alpibectir
CAS :<p>Alpibectir has antibacterial activity [1].</p>Formule :C12H14F6N2O2Couleur et forme :SolidMasse moléculaire :332.24PAV-104
CAS :<p>PAV-104 inhibits the replication of SARS-CoV-2 at a MOI of 0.01. It interacts with the SARS-CoV-2 nucleocapsid (N) and disrupts its oligomerization, thereby preventing particle assembly.</p>Formule :C29H35N5O6SCouleur et forme :SolidMasse moléculaire :581.68CYP2C19-IN-1
<p>CYP2C19-IN-1: potent CYP2C19 inhibitor, non-genotoxic, non-hepatotoxic, blocks RdRP (Ki: 6.16 μM), useful for ZIKV research.</p>Formule :C26H26N2O6SCouleur et forme :SolidMasse moléculaire :494.56Benzisothiazolone
CAS :<p>Benzisothiazolone is an isothiazolinone fungicide that demonstrates growth inhibitory activity against Escherichia coli ATCC 8739 and yeast NCYC 1354. It is utilized in studies investigating growth inhibition models.</p>Formule :C7H5NOSCouleur et forme :SolidMasse moléculaire :151.19Gallinamide A
CAS :<p>Gallinamide A is a potent inhibitor of cathepsin L with an IC 50 value of 17.6 pM.</p>Formule :C31H52N4O7Couleur et forme :SolidMasse moléculaire :592.77BM635 hydrochloride
<p>BM635 hydrochloride, an MmpL3 inhibitor, strongly blocks Divergent bacteriophage H37Rv (MIC50: 0.08 μM), with doubled in vivo potency.</p>Formule :C25H30ClFN2OCouleur et forme :SolidMasse moléculaire :428.97Methyl 3-oxodecanoate
CAS :<p>Methyl 3-oxodecanoate exhibits virulence factor activity against human pathogens and shows effects on Synechococcus elongatus (a species of fluorescent algae) as well as on culture supernatant. Additionally, Methyl 3-oxodecanoate inhibits DNA synthesis by suppressing protein synthesis at the translation initiation level.</p>Formule :C11H20O3Couleur et forme :SolidMasse moléculaire :200.275Lentiginosine
CAS :<p>Lentiginosine is a selective amyloglucosidase inhibitor.</p>Formule :C8H15NO2Couleur et forme :SolidMasse moléculaire :157.21Ipronidazole
CAS :<p>Ipronidazole (RO-71554) is an orally effective antiprotozoal agent used to prevent and ameliorate histomoniasis in turkeys, commonly referred to as blackhead disease.</p>Formule :C7H11N3O2Couleur et forme :SolidMasse moléculaire :169.18Saroaspidin B
CAS :<p>Saroaspidin B is a dimeric form of a biphenyl triphenol, characterized as an antibiotic compound.</p>Formule :C25H32O8Couleur et forme :SolidMasse moléculaire :460.52Polθ-IN-5
CAS :<p>Polθ-IN-5 (Compound 139) is an inhibitor of DNA polymerase theta (Polθ) that exhibits antitumor activity.</p>Formule :C23H18ClF2N7O3SCouleur et forme :SolidMasse moléculaire :545.95RAD51-IN-6
CAS :<p>RAD51-IN-6, a potent RAD51 gene inhibitor, may help research mitochondrial disorders. (WO2021164746A1, cmpd 23)</p>Formule :C27H40N3O5PSCouleur et forme :SolidMasse moléculaire :549.66EFdA-TP tetrasodium
CAS :<p>EFdA-TP tetrasodium is a potent HIV-1 inhibitor that blocks DNA synthesis as an ICT or DCT.</p>Formule :C12H11FN5Na4O12P3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :621.12Bersiporocin
CAS :<p>Bersiporocin is a novel prolyl-tRNA synthetase (PRS) inhibitor that exerts antifibrotic effects through downregulation of collagen synthesis in IPF.</p>Formule :C15H19Cl2N3ODegré de pureté :98.88% - 99.79%Couleur et forme :SolidMasse moléculaire :328.24Cefclidin
CAS :<p>Cefclidin (Cefclidine) is a cephalosporin compound.</p>Formule :C21H26N8O6S2Couleur et forme :SolidMasse moléculaire :550.611HIV-1 inhibitor-13
<p>HIV-1 inhibitor-13: oral NNRTI, IC50=0.14μM for HIV-1 RT, effective on resistant strains (EC50=2.85-18nM).</p>Formule :C30H32N6O3Couleur et forme :SolidMasse moléculaire :524.61LpxC-IN-10
CAS :<p>LpxC-IN-10 is a selective LpxC inhibitor with an MIC of 0.5 μg/mL against E. coli and K. pneumoniae and is capable of being used to study bacterial infections.</p>Formule :C30H31N5O3Couleur et forme :SolidMasse moléculaire :509.6AB25583
CAS :<p>AB25583 is a small molecule inhibitor of Polθ helicase (Polθ-hel) with an IC50 of 6 nM. It selectively kills cells deficient in BRCA1/2 and synergizes with Olaparib in cancer cells harboring pathogenic BRCA1/2 mutations. AB25583 can be utilized in tumor research.</p>Formule :C22H17ClN4O3SCouleur et forme :SolidMasse moléculaire :452.918-Hydroxyerythromycin A
CAS :<p>8-Hydroxyerythromycin A is a semi-synthetic antibiotic with antibacterial activity.</p>Formule :C37H67NO14Couleur et forme :SolidMasse moléculaire :749.926WRN inhibitor 13
CAS :<p>WRN inhibitor 13 is an inhibitor of the WRN helicase with a pIC50 value ranging from 6 to 7.</p>Formule :C16H20N2O5SCouleur et forme :SolidMasse moléculaire :352.405Antitubercular agent-16
<p>Compound 5q is a potent antitubercular with low MIC90 values (0.40-23.51 μg/mL) against M. tuberculosis strains, showing minimal cytotoxicity.</p>Formule :C21H27N3SCouleur et forme :SolidMasse moléculaire :353.52ACHN-975 TFA
CAS :<p>ACHN-975 TFA is a selective LpxC inhibitor with a subnanomolar inhibitory. It is against a wide range of gram-negative bacterias with low MIC values (≤1 μg/mL).</p>Formule :C22H24F3N3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :483.4377Secutrelvir
CAS :<p>Secutrelvir inhibits the 3CL protease (3CL protease), thereby exhibiting antiviral activity by preventing the replication of SARS-CoV-2.</p>Formule :C23H16Cl2F3N5O2Couleur et forme :SolidMasse moléculaire :522.307Carumonam Sodium
CAS :<p>Carumonam Sodium is a monobactam, penicillin-binding protein inhibitor. It is used as antibacterials.</p>Formule :C12H12N6Na2O10S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :510.37Succinate dehydrogenase-IN-8
CAS :<p>Succinate dehydrogenase-IN-8 (compound i19) is a potent inhibitor of succinate dehydrogenase (SDH). This indanoyl amino acid derivative demonstrates strong antifungal activity in vitro against Rhizoctonia solani (EC50 = 0.1843 mg/L), Botrytis cinerea (EC50 = 0.4829 mg/L), and Sclerotinia sclerotiorum (EC50 = 0.1349 mg/L).</p>Formule :C22H19Cl2F2N5O2Couleur et forme :SolidMasse moléculaire :494.32FNC-TP trisodium
<p>FNC-TP trisodium, active intracellular FNC form, inhibits NRTI, fights HIV, HBV, and HCV.</p>Formule :C9H11FN6Na3O13P3Couleur et forme :SolidMasse moléculaire :592.11MT0703
CAS :<p>MT0703 is a cephalosporin antibiotic featuring an aminothiazolylglycyl moiety with a 1,5-dihydroxy-4-pyridinone-2-carbonyl group, displaying potent activity against Pseudomonas species.</p>Formule :C26H25N7O9S3Couleur et forme :SolidMasse moléculaire :675.71Saussureamine C
CAS :<p>Saussureamine C is an inhibitor of H274Y and N294S mutants.</p>Formule :C19H26N2O5Couleur et forme :SolidMasse moléculaire :362.42Antibacterial agent 80
<p>Antibacterial agent 80 (compound 20) has antibacterial activity [1].</p>Formule :C14H21N3S2Couleur et forme :SolidMasse moléculaire :295.47RmlA-IN-2
<p>RmlA-IN-2: Strong RmlA blocker, hinders l-rhamnose synthesis & alters bacterial wall permeability (IC50: 0.303 μM).</p>Formule :C22H26BrN5O4SCouleur et forme :SolidMasse moléculaire :536.44UNC0638 hydrate
CAS :<p>UNC0638 hydrate selectively inhibits G9a and GLP histone methyltransferases with IC50 values of 15 nM and 19 nM, respectively. It is effective in inhibiting invasion and migration of TNBC cells in vitro. Additionally, UNC0638 hydrate acts as an inhibitor of EHMT1/2 and induces the expression of fetal hemoglobin (HbF) in cultures of human erythroid progenitor cells. Furthermore, it exhibits antiviral activity against FMDV (foot-and-mouth disease virus) and VSV (vesicular stomatitis virus), demonstrating remarkable potency and selectivity across various epigenetic and non-epigenetic targets.</p>Formule :C30H49N5O3Couleur et forme :SolidMasse moléculaire :527.74Antibacterial agent 169
CAS :<p>Antibacterial agent 169 (Compound 28), a pyrrolamide-type GyrB/ParE inhibitor, exhibits antibacterial properties by inhibiting Gyrase and Topo IV in Staphylococcus aureus. It has IC 50 values of 49 nmol/L and 1.513 μmol/L, respectively [1].</p>Formule :C19H25Cl2N5O3Couleur et forme :SolidMasse moléculaire :442.34RSV-IN-7
CAS :<p>RSV-IN-7 (example 253) is a RSV inhibitor ( EC 50 : < 0.4 μΜ) .</p>Formule :C27H22F3N7O3Couleur et forme :SolidMasse moléculaire :549.50Metallo-β-lactamase-IN-13
CAS :<p>Metallo-β-lactamase-IN-13 (Compound 13i) serves as a pan Metallo-β-Lactamase inhibitor with extended activity against Gram-negative (GN) bacteria expressing metallo-β-lactamases. It exhibits antibacterial properties effective against P. aeruginosa [1].</p>Formule :C15H10F3N7O2S2Couleur et forme :SolidMasse moléculaire :441.41UMPK ligand 1
CAS :<p>UMPK ligand 1 (ZINC07785412) serves as a ligand for uridine monophosphate kinase (UMPK).</p>Formule :C15H22N4O5SCouleur et forme :SolidMasse moléculaire :370.424Antifungal agent 12
<p>Antifungal agent 12 is a new fluconazole-like compound that exhibits good antifungal effects.</p>Formule :C20H16F3N7O2S2Couleur et forme :SolidMasse moléculaire :507.51BioA-IN-1
CAS :<p>BioA-IN-1 (Compound 15) is an inhibitor of the key enzyme BioA in the biotin biosynthesis pathway of Mycobacterium tuberculosis, with an IC50 value of 0.195 μM. It exhibits antibacterial activity without cytotoxicity.</p>Formule :C18H17NO3SCouleur et forme :SolidMasse moléculaire :327.397Antiviral agent 67
CAS :<p>Antiviralagent 67 (compound PC6) is an inhibitor of DENVNS5 (RNA-dependent RNA polymerase) with a Ki value of 1.12 nM.</p>Formule :C19H19N3OCouleur et forme :SolidMasse moléculaire :305.374K13787
CAS :<p>K13787 is an acetohydroxy acid synthase (AHAS) inhibitor with antibacterial properties. It exhibits antimicrobial activity against various non-tuberculous mycobacteria (NTM) as well as clarithromycin (CLR) resistant strains.</p>Formule :C14H11F2N5O4SCouleur et forme :SolidMasse moléculaire :383.33Altersolanol A
CAS :<p>Altersolanol A (Stemphylin; NSC 173943) demonstrates effective antimicrobial properties, inhibiting the growth of Bacillus subtilis and Pseudomonas aeruginosa with a minimum inhibitory concentration (MIC) ranging from 25-100 μg/mL. Additionally, it shows no phytotoxic effects on Taxus at a concentration of 4 μg/μL.</p>Formule :C16H16O8Couleur et forme :SolidMasse moléculaire :336.29LasR-IN-2
<p>LasR-IN-2 blocks LasR via H-bond with TRY-56, useful in bacterial infection and CF research.</p>Formule :C21H16ClN3O2Couleur et forme :SolidMasse moléculaire :377.829-tert-Butyldoxycycline
CAS :<p>9-tert-Butyldoxycycline exhibits immunomodulatory activity by altering the polarization state of polymorphonuclear neutrophils and ameliorating inflammatory responses in ischemia-reperfusion injury models. Additionally, 9-tert-Butyldoxycycline serves as a ligand for the "Tet-On" inducible gene expression system.</p>Formule :C26H32N2O8Couleur et forme :SolidMasse moléculaire :500.541SID 26681509 quarterhydrate
<p>SID 26681509 is a selective inhibitor of cathepsin L (IC50: 56 nM) and blocks Plasmodium falciparum (IC50: 15.4 μM) and Leishmania major (IC50: 12.5 μM).</p>Formule :C27H35N5O6SCouleur et forme :SolidMasse moléculaire :544.16Cyclophilin inhibitor 1
CAS :<p>Cyclophilin inhibitor 1: orally available, Kd 5 nM, potent against HCV, EC50 for HCV 2a is 98 nM.</p>Formule :C31H39N5O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :593.67Antibacterial agent 266
CAS :<p>Antibacterialagent 266 (Compound C5) is an inhibitor of plant pathogenic bacteria that disrupts the integrity of bacterial cell membranes. It exhibits an EC50 of 24.1 μg/mL against Xanthomonasoryzaepvoryzae (Xoo) and 39.0 μg/mL against X. axonopodispvcitri (Xac). Antibacterialagent 266 is valuable for research in plant pathology and the development of agricultural antibacterial agents.</p>Formule :C13H11N3OCouleur et forme :SolidMasse moléculaire :225.246Meclocycline
CAS :<p>Meclocycline: a tetracycline antibiotic, inhibits LDH, reduces cell toxicity from mutant huntingtin, doesn't change protein levels in PC12 cells.</p>Formule :C22H21ClN2O8Couleur et forme :SolidMasse moléculaire :476.86BPR3P0128
CAS :<p>BPR3P0128, a non-nucleoside RNA-dependent RNA polymerase (RdRp) inhibitor, is effective orally and can inhibit various SARS-CoV-2 variants. It exhibits EC 50 values of 0.62 µM for SARS-CoV-2 and 0.14 µM for HCoV-229E, demonstrating potent anti-pancoronavirus activity at submicromolar concentrations. Additionally, BPR3P0128 displays synergistic antiviral effects when used in combination with Remdesivir [1].</p>Formule :C22H18BrN3O2Couleur et forme :SolidMasse moléculaire :436.30KWR095
CAS :<p>KWR095 is an orally active inhibitor of WRN, demonstrating an IC50 of 0.032 μM against WRN ATPase. It disrupts the double-stranded helicase activity of WRN and inhibits tumor cell proliferation, exhibiting antitumor properties.</p>Formule :C33H31ClF3N9O4Couleur et forme :SolidMasse moléculaire :710.105RAD51-IN-7
CAS :<p>RAD51-IN-7 inhibits RAD51 gene, with potential for mitochondrial disorders. (From WO2021164746A1, cmpd 71)</p>Formule :C25H31N5O4S2Couleur et forme :SolidMasse moléculaire :529.67Anthelvencin A
CAS :<p>Anthelvencin A is a pyrrolylamide metabolite with moderate antibacterial and anthelmintic activity.</p>Formule :C19H25N9O3Couleur et forme :SolidMasse moléculaire :427.46Antibacterial agent 62
<p>Novel anti-TB agent 62 is a redox compound with bactericidal activity against active and dormant bacteria.</p>Formule :C24H33BrN2O2Couleur et forme :SolidMasse moléculaire :461.44SARS-CoV-2-IN-80
CAS :<p>SARS-CoV-2-IN-80 (compound 13), identified as a potent inhibitor of SARS-CoV-2 3CLpro, exhibits an IC50 value of 0.964 µM [1].</p>Formule :C16H10O2SCouleur et forme :SolidMasse moléculaire :266.31DHX9-IN-9
CAS :<p>DHX9-IN-9 (509) acts as an inhibitor of the RNA helicase DHX9, demonstrating an EC50 of 0.0177 μM in DHX9 cellular target engagement, primarily utilized in cancer research [1].</p>Formule :C21H21ClFN5O3S2Couleur et forme :SolidMasse moléculaire :510BAY-364
CAS :<p>BAY-364 (BAY-299N) functions as an inhibitor targeting the second bromine domain in TAF1, demonstrating inhibitory effects on TAF1 in Kasumi-1 cells, CD34+</p>Formule :C23H19N3O4Couleur et forme :SolidMasse moléculaire :401.41SARS 3CLpro-IN-1
CAS :<p>SARS 3CLpro-IN-1: stereospecific SARS 3CL protease inhibitor, octahydroisochromene class, IC50 = 95 μM.</p>Formule :C22H38N4O2Couleur et forme :SolidMasse moléculaire :390.56WRN inhibitor 7
CAS :<p>WRN inhibitor 7 (Compound h6), a potent inhibitor of Werner syndrome helicase, demonstrates effective suppression of WRN's helicase and ATPase activities with IC50 values of 9.8 μM and 15.8 μM, respectively. This compound is utilized in the study of microsatellite instable (MSI) cancers [1].</p>Formule :C27H23N3O6Couleur et forme :SolidMasse moléculaire :485.49Antibacterial agent 87
<p>Antibacterial agent 87 is an effective antibacterial agent that acts on MRSA (MIC: 0.125 μg/ml), MRSE (MIC: 0.0625 μg/ml) and S. aureus (MIC: 0.0625 μg/ml).</p>Formule :C31H46N2O6SCouleur et forme :SolidMasse moléculaire :574.77DNA crosslinker 6
CAS :<p>DNA crosslinker 6 (compound 1) is an anti-mitotic agent known for its strong binding affinity to AT-DNA and inhibition of AT-hook 1 binding to DNA (IC50=0.03 µM). Additionally, it exhibits anti-protozoal activity, effectively inhibiting T. brucei with an EC50 of 0.83 µM.</p>Formule :C19H21N7OCouleur et forme :SolidMasse moléculaire :363.42Neuraminidase-IN-18
CAS :<p>Neuraminidase-IN-18 (compound N5), a novel polyheterocyclic neuraminidase (NA) inhibitor, demonstrates significant inhibitory activity against H5N1 NA, with an IC 50 of 0.14 μM against the wild-type H5N1 NA and 0.27 μM against the H5N1-H274Y mutant NA. This compound effectively binds to NAs, inhibiting influenza virus replication at the cellular level [1].</p>Formule :C22H18FN3O3SCouleur et forme :SolidMasse moléculaire :423.46Ladirubicin
CAS :<p>Ladirubicin, as an anthracyclines analog is the leading compound of alkylcyclines.</p>Formule :C29H31NO11SCouleur et forme :SolidMasse moléculaire :601.62Antibacterial agent 188
CAS :<p>Compound 2d (Antibacterial agent 188) serves as an antibacterial agent that suppresses the activity of dermatophytes [1].</p>Formule :C12H10N4SCouleur et forme :SolidMasse moléculaire :242.3Ciluprevir
CAS :<p>Ciluprevir is a selective HCV NS3 protease inhibitor, effective against non-genotype-1 HCV; less potent for genotypes 2/3.</p>Formule :C40H50N6O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :774.93GHP-88309
CAS :<p>GHP-88309 is an orally active, broad-spectrum anti-paramyxovirus agent that targets viral polymerase, interrupting viral RNA synthesis. It effectively inhibits respiratory syncytial virus (RSV), measles virus (MeV), and canine distemper virus (CDV) with an EC50 of 0.06-1.2 μM. In mouse models, GHP-88309 demonstrates significant anti-infective activity.</p>Formule :C16H11FN2OCouleur et forme :SolidMasse moléculaire :266.27Menoctone
CAS :<p>Menoctone is an orally effective antimalarial agent that inhibits blood-induced rodent malaria. It enhances the antimalarial effects of chloroquine or quinine, making it useful for malaria research.</p>Formule :C24H32O3Couleur et forme :SolidMasse moléculaire :368.51N-Cbz-L-Cysteine
CAS :<p>N-Cbz-L-Cysteine (Cbz-cysteine) (compound 5) functions as a potent inhibitor of β-lactamase II, exhibiting a K i value of 97 µM [1].</p>Formule :C11H13NO4SCouleur et forme :SolidMasse moléculaire :255.29Anti-MRSA agent 2
CAS :<p>Anti-MRSA agent 2 inhibits MRSA at 0.098 μg/ml, with low toxicity and disrupts bacterial membranes and DNA.</p>Formule :C18H10Br2N2OCouleur et forme :SolidMasse moléculaire :430.09Cap-dependent endonuclease-IN-6
CAS :<p>Cap-dependent endonuclease-IN-6 (compound 13) is a Cap-dependent endonuclease (CEN) inhibitor that inhibits influenza virus.</p>Formule :C23H21N3O3SCouleur et forme :SolidMasse moléculaire :419.5CDA-IN-2
CAS :<p>CDA-IN-2 (Compound VS#2-3) is an inhibitor of chitin deacetylase (CDA) that exhibits antifungal properties. At a concentration of 100 μM, it inhibits P. xanthii's CDAPxCDA1 by 83.7% and PxCDA2 by 74.5%. CDA-IN-2 is applicable in research on agricultural fungal diseases, including resistance to powdery mildew and gray mold.</p>Formule :C17H16N2O7Couleur et forme :SolidMasse moléculaire :360.318Cap-dependent endonuclease-IN-17
CAS :<p>CEN inhibitor IN-17 targets influenza A/H3N2; IC50: 1.29 μM. From patent CN112898346A, DSC701.</p>Formule :C24H20F2N3O7PSCouleur et forme :SolidMasse moléculaire :563.47RECTAS-2.0
CAS :<p>RECTAS-2.0 is a small molecule designed to correct RNA mis-splicing caused by the GLA c.639+919G>A mutation, intended for research in Fabry disease.</p>Formule :C18H17ClN4O4Couleur et forme :SolidMasse moléculaire :388.805Antifungal agent 125
CAS :<p>Antifungalagent 125 (compound 4H) is a potent succinate dehydrogenase (SDH) inhibitor with an IC50 of 3.59 μg/mL and exhibits fungicidal activity against Alternaria alternata.</p>Formule :C13H10BrNO4SCouleur et forme :SolidMasse moléculaire :356.192Lavendomycin
CAS :<p>Lavendomycin can be extracted from Streptomyces lavendulae and has active against Gram-positive bacteria.</p>Formule :C29H50N10O8Couleur et forme :SolidMasse moléculaire :666.77Avibactam sodium dihydrate
<p>Avibactam sodium dihydrate (NXL-104) is a reversible covalent inhibitor for CTX-M-15 and TEM-1 β-lactamases with IC50s of 5 nM and 8 nM.</p>Formule :C7H14N3NaO8SCouleur et forme :SolidMasse moléculaire :323.26Antimalarial agent 9
<p>Antimalarial 9, a quinoline-imidazole derivative, effectively targets CQ-susceptible (IC50-0.14 μM) and MDR strains (IC50-0.41 μM) with low toxicity.</p>Formule :C28H32BrN3O2Couleur et forme :SolidMasse moléculaire :522.48CMX990
CAS :<p>CMX990, a SARS-CoV-2 3CL protease inhibitor, exhibits EC90 values of 9.6 nM in human bronchial epithelial cells (HBECs) and 101 nM in HeLa-ACE2 cells. It also demonstrates good ADME and pharmacokinetic properties [1].</p>Formule :C22H32F3N3O6Couleur et forme :SolidMasse moléculaire :491.50Narlaprevir
CAS :<p>Narlaprevir (SCH 900518) is an HCV NS3 inhibitor with anti-HCV activity, inhibiting SARS-CoV-2, and useful in virus infection research.</p>Formule :C36H61N5O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :707.96InhA-IN-7
CAS :<p>InhA-IN-7 (Compound 11), a derivative of Triclocan, shows inhibitory activity against enoyl-acyl carrier protein reductase (InhA) with an IC50 of 96 nM. It effectively inhibits the proliferation of both wildtype and mutant strains of Mycobacterium tuberculosis, exhibiting minimum inhibitory concentrations (MICs) ranging from 19 to 75 μM [1].</p>Formule :C17H18Cl2O2Couleur et forme :SolidMasse moléculaire :325.23GSK5852
<p>GSK5852, an HCV NS5B inhibitor, has IC50 of 50 nM; potently fights HCV with EC50 of 3.0 nM for GT1a and 1.7 nM for GT1b.</p>Formule :C27H27BF2N2O6SCouleur et forme :SolidMasse moléculaire :556.39Anti-MRSA agent 3
CAS :<p>Anti-MRSA agent 3 targets MRSA with 0.098 μg/ml MIC, low toxicity, binds DNA, and disrupts cell walls/membranes.</p>Formule :C29H18BrN3O2Couleur et forme :SolidMasse moléculaire :520.386Chitin synthase inhibitor 12
<p>Chitin synthase inhibitor 12: potent CHS blocker (IC50: 0.16 mM), broad-spectrum antifungal, effective against resistant strains. Useful in IFI research.</p>Formule :C23H21ClFN3O5Couleur et forme :SolidMasse moléculaire :473.88Mycobacterium Tuberculosis-IN-6
CAS :<p>Mycobacterium Tuberculosis-IN-6 (compound b1) is an inhibitor of the enoyl reductase InhA from Mycobacterium tuberculosis, with an IC50 value of 7.74 μM. It is useful in antibacterial research.</p>Formule :C19H20FNOCouleur et forme :SolidMasse moléculaire :297.367(Rac)-Plevitrexed
CAS :<p>(Rac)-Plevitrexed is a racemate of Plevitrexed. Plevitrexed is an orally active and potent inhibitor of thymidylate synthase (TS).</p>Formule :C26H25FN8O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :532.53Gln-AMS TFA
<p>Gln-AMS (TFA) is a type Ia amido-tRNA synthetase (AARS) inhibitor with a Ki value of 1.32 μM for glutaminyl-tRNA synthetase.</p>Formule :C17H23F3N8O10SCouleur et forme :SolidMasse moléculaire :588.47PLP_Snyder530
<p>PLP_Snyder530, a potent PL pro inhibitor, halts SARS-CoV-2 by triggering protease conformation changes.</p>Formule :C24H24N2O2Couleur et forme :SolidMasse moléculaire :372.46Antileishmanial agent-6
<p>Antileishmanial agent-6: potent against Leishmania donovani, IC50 0.54μM; cytotoxic IC50 10.2μM.</p>Formule :C24H26O8Couleur et forme :SolidMasse moléculaire :442.46Anti-infective agent 10
CAS :<p>Anti-infective agent 10 (Compound Example 30) is an ns5b polymerase inhibitor that functions as an anti-HCV agent.</p>Formule :C26H25N3O7SCouleur et forme :SolidMasse moléculaire :523.56QPX7728 bis-acetoxy methyl ester
CAS :<p>QPX7728 bis-acetoxy methyl ester is an inhibitor of boronic acid β-lactamase.</p>Formule :C15H14BFO8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :352.08
