Microbiologie/Virologie
Les inhibiteurs en microbiologie et virologie sont des composés qui ciblent les microorganismes, y compris les bactéries, les virus et les champignons, perturbant leur croissance, leur réplication ou leur survie. Ces inhibiteurs sont essentiels pour étudier la pathogénie microbienne, comprendre les mécanismes de résistance et développer de nouvelles thérapies antimicrobiennes et antivirales. Les inhibiteurs de cette catégorie sont utilisés pour combattre les maladies infectieuses, explorer l'écologie microbienne et étudier les interactions hôte-pathogène. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en microbiologie et virologie pour soutenir vos recherches en maladies infectieuses, microbiologie et virologie.
Sous-catégories appartenant à la catégorie "Microbiologie/Virologie"
- Antibactérien(2.949 produits)
- Antibiotique(918 produits)
- Antifection(23 produits)
- DHFR(32 produits)
- Synthèse ADN/ARN(706 produits)
- VHB(176 produits)
- Protéase du VIH(447 produits)
- HSV(91 produits)
- Intégrase(2 produits)
- Ribosome(13 produits)
Affichez 2 plus de sous-catégories
5832 produits trouvés pour "Microbiologie/Virologie"
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NBD-10007
CAS :<p>NBD-10007 is an inhibitor of HIV-1 entry.</p>Formule :C20H25ClN4O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :436.96trans-RdRP-IN-5
<p>Trans-RdRP-IN-5 is a potent inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), with applications in influenza virus research.</p>Formule :C23H21N3O5Couleur et forme :SolidMasse moléculaire :419.43EBOV-GP-IN-1
<p>EBOV-GP-IN-1 (Compound 28) is a potent inhibitor of Ebola entry, acting on the Ebola virus envelope glycoprotein (EBOV-GP) (IC50: 0.05 μM).</p>Formule :C25H40ClN3O2Couleur et forme :SolidMasse moléculaire :450.06Meclocycline
CAS :<p>Meclocycline: a tetracycline antibiotic, inhibits LDH, reduces cell toxicity from mutant huntingtin, doesn't change protein levels in PC12 cells.</p>Formule :C22H21ClN2O8Couleur et forme :SolidMasse moléculaire :476.86Antibacterial agent 113
<p>Antibacterial agent 113 targets multiple bacteria including P. aeruginosa and E. coli, showing efficacy at MIC 15625 μM.</p>Formule :C29H18ClN5OCouleur et forme :SolidMasse moléculaire :487.941,5-Dideoxy-1,5-imino-D-mannitol
CAS :<p>1,5-Dideoxy-1,5-imino-D-mannitol is an antibiotic with antibacterial properties.</p>Formule :C6H13NO4Couleur et forme :SolidMasse moléculaire :163.172Teslexivir
CAS :<p>Teslexivir is a topical antiviral agent that is an effective and selective inhibitor of the interaction between two essential viral proteins, E1 and E2.</p>Formule :C35H36BrN3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :642.58HCV-IN-38
<p>Potent oral HCV inhibitor HCV-IN-38 has 15 nM EC50, 431 SI, high efficacy, and low toxicity.</p>Formule :C22H24ClF3N4O4Couleur et forme :SolidMasse moléculaire :500.9Antibacterial agent 169
CAS :<p>Antibacterial agent 169 (Compound 28), a pyrrolamide-type GyrB/ParE inhibitor, exhibits antibacterial properties by inhibiting Gyrase and Topo IV in Staphylococcus aureus. It has IC 50 values of 49 nmol/L and 1.513 μmol/L, respectively [1].</p>Formule :C19H25Cl2N5O3Couleur et forme :SolidMasse moléculaire :442.34DXR-IN-3
CAS :<p>DXR-IN-3 is an anti-Toxoplasma DXR inhibitor. It exhibits in vitro activity against the TgDXR enzyme, with an IC50 value of 0.62 μM and a Ki value of 0.19 μM. Furthermore, DXR-IN-3 can inhibit the proliferation of Toxoplasma, displaying an IC50 value of 5.46 μM.</p>Formule :C10H12Cl2NO5PSCouleur et forme :SolidMasse moléculaire :360.15Urease-IN-2
<p>Urease-IN-2 is a non-competitive inhibitor of urease (IC50: 0.94 μM, Ki: 1.6 μM) that non-competitively inhibits Jack bean urease (JBU).</p>Formule :C26H25N5O5S3Couleur et forme :SolidMasse moléculaire :583.7Antimalarial agent 3
<p>Antimalarial agent 3 has a potent IC50 of 0.035 μM against Plasmodium and high selectivity for mammalian cells.</p>Formule :C15H16BrN3O2Couleur et forme :SolidMasse moléculaire :350.21Antitrypanosomal agent 5
<p>Antitrypanosal agent 5 is a selective anti-trypanosomal agent that acts on T. brucei (IC50: 1 nM) and HEK293 cells (IC50: 483.3 μM).</p>Formule :C30H30N6O4SCouleur et forme :SolidMasse moléculaire :570.66GT-055
<p>GT-055 (LCB18-055) is a novel inhibitor of broad-spectrum β-lactamase.</p>Formule :C13H20F3N5O8SCouleur et forme :SolidMasse moléculaire :463.39PAV-104
CAS :<p>PAV-104 inhibits the replication of SARS-CoV-2 at a MOI of 0.01. It interacts with the SARS-CoV-2 nucleocapsid (N) and disrupts its oligomerization, thereby preventing particle assembly.</p>Formule :C29H35N5O6SCouleur et forme :SolidMasse moléculaire :581.68MK-8876
CAS :<p>MK-8876 is an Inhibitor of HCV NS5B Site D.</p>Formule :C32H24F2N4O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :614.629-tert-Butyldoxycycline
CAS :<p>9-tert-Butyldoxycycline exhibits immunomodulatory activity by altering the polarization state of polymorphonuclear neutrophils and ameliorating inflammatory responses in ischemia-reperfusion injury models. Additionally, 9-tert-Butyldoxycycline serves as a ligand for the "Tet-On" inducible gene expression system.</p>Formule :C26H32N2O8Couleur et forme :SolidMasse moléculaire :500.541Cap-dependent endonuclease-IN-7
CAS :<p>Cap-dependent endonuclease-IN-7, a potent CEN inhibitor, blocks viral mRNA synthesis and virus spread, with research use for influenza A, B, C.</p>Formule :C36H28FN3O7SCouleur et forme :SolidMasse moléculaire :665.69GSK3739936
CAS :<p>GSK3739936 inhibits HIV-1 integrase (IC50: 11.1 nM, EC50: 1.7 nM), weak on CYP (IC50 >24.3 μM), rapid absorption, moderate clearance, high oral availability.</p>Formule :C34H43FN2O4Couleur et forme :SolidMasse moléculaire :562.71Avibactam sodium dihydrate
<p>Avibactam sodium dihydrate (NXL-104) is a reversible covalent inhibitor for CTX-M-15 and TEM-1 β-lactamases with IC50s of 5 nM and 8 nM.</p>Formule :C7H14N3NaO8SCouleur et forme :SolidMasse moléculaire :323.26(4-Aminobenzoyl)-D-glutamic acid
CAS :<p>(4-Aminobenzoyl)-D-glutamic acid (Compound 17) exhibits competitive inhibitory activity against the H2-pterin synthesis system, affecting folic acid synthesis and subsequently inhibiting bacterial growth.</p>Formule :C12H14N2O5Couleur et forme :SolidMasse moléculaire :266.25LasR-IN-2
<p>LasR-IN-2 blocks LasR via H-bond with TRY-56, useful in bacterial infection and CF research.</p>Formule :C21H16ClN3O2Couleur et forme :SolidMasse moléculaire :377.82L 702007
CAS :<p>L 702007 is an inhibitor of HIV-1 reverse transcriptase.</p>Formule :C18H25N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :315.41Cap-dependent endonuclease-IN-10
CAS :<p>Cap-dependent endonuclease-IN-10, with low toxicity & good stability, effectively inhibits flu viruses and shows promise against A, B, C types.</p>Formule :C25H18F2N4O5SCouleur et forme :SolidMasse moléculaire :524.50Xanthosine-5'-Triphosphate trisodium
CAS :<p>Xanthosine-5'-Triphosphate (5'-XTP) trisodium is a nucleotide formed through the deamination of purine bases. It serves as a substrate for inosine triphosphate pyrophosphatase (ITPase).</p>Formule :C10H12N4Na3O15P3Couleur et forme :SolidMasse moléculaire :590.111Anti-Trypanosoma cruzi agent-2
<p>Compd 3b: anti-trypanosomal, IC50 0.51 μM (NINOA), 3.06 μM (INC-5), also combats T. gondii.</p>Formule :C17H10ClNO5Couleur et forme :SolidMasse moléculaire :343.72A25822B
CAS :<p>A25822B is an antifungal agent.</p>Formule :C28H45NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :411.66NS2B/NS3-IN-2
<p>Potent dengue inhibitor NS2B/NS3-IN-2 (IC50: 6 nM, Ki: 0.66 μM) boosts cell viability, non-toxic.</p>Formule :C24H21N3O5SCouleur et forme :SolidMasse moléculaire :463.51HBV-IN-20
<p>HBV-IN-20 is a potent, orally active HBV inhibitor (EC50: 0.46 μM). HBV-IN-20 is a classical type II CpAM (core protein assembly regulator).</p>Couleur et forme :SolidPyriftalid
CAS :<p>Pyriftalid is a novel insecticide known for its potent inhibitory activity against a variety of pests. It is widely utilized in agriculture to effectively manage crop pests, thereby enhancing both the yield and quality of crops. Additionally, research is exploring the use of Pyriftalid in boosting plant resistance to pests and diseases.</p>Formule :C15H14N2O4SCouleur et forme :SolidMasse moléculaire :318.35Triazophos
CAS :<p>Triazophos is a non-systemic pesticide that acts as an acetylcholinesterase (AChE) inhibitor, forming a covalent and irreversible bond with the acetylcholine binding site. This action blocks the hydrolysis of acetylcholine, leading to increased excitability. It is effective against a wide range of soil insects and mites, including aphids, thrips, midges, beetles, lepidopteran larvae, mole crickets, and red spiders. Triazophos is suitable for use on various crops such as ornamental plants, cotton, rice, corn, soybeans, oil palm, olives, and coffee.</p>Formule :C12H16N3O3PSCouleur et forme :SolidMasse moléculaire :313.31Narlaprevir
CAS :<p>Narlaprevir (SCH 900518) is an HCV NS3 inhibitor with anti-HCV activity, inhibiting SARS-CoV-2, and useful in virus infection research.</p>Formule :C36H61N5O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :707.96Neuraminidase-IN-4
<p>Neuraminidase-IN-4 inhibits neuraminidase (EC50: 1.59 μM) and has strong anti-H5N1 activity.</p>Formule :C21H20N2O6SCouleur et forme :SolidMasse moléculaire :428.46MIV-150
CAS :<p>MIV-150 is a nonnucleoside inhibitor of reverse transcriptase (NNRT). MIV-150 also blocking HIV-1 and HIV-2 infections (EC50<1 nM against HIV-1/HIV-2MN).</p>Formule :C19H17FN4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :368.36FWM-1
<p>FWM-1 blocks SARS-CoV-2 NSP13, hinders ATP binding, with -328.6 kcal/mol binding energy.</p>Formule :C15H11ClN4O4S2Couleur et forme :SolidMasse moléculaire :410.86Purine phosphoribosyltransferase-IN-2
<p>Purine PRTase-IN-2 inhibits Pf, Pv, Tbr PRT; Ki: 30, 20, 2 nM.</p>Formule :C11H15N5Na4O10P2Couleur et forme :SolidMasse moléculaire :531.17NRTT-IN-1
CAS :<p>NRTT-IN-1 (Compound 1) is an inhibitor of the nucleoside reverse transcriptase translocation (NRTT), effectively blocking HIV DNA synthesis and viral replication.</p>Formule :C28H24FN5O5Couleur et forme :SolidMasse moléculaire :529.519Trypanothione synthetase-IN-4
<p>Trypanothione synthetase-IN-4, an L. infantum inhibitor, has potent anti-leishmanicidal properties (EC50: 0.6 μM).</p>Formule :C29H52INO2Couleur et forme :SolidMasse moléculaire :573.63Xeruborbactam isoboxil
CAS :<p>Xeruborbactam isoboxil is a β-lactamase (beta-lactamase) inhibitor.</p>Formule :C15H16BFO6Couleur et forme :SolidMasse moléculaire :322.093bc1 Complex-IN-1
CAS :<p>Bc1 Complex-IN-1 (compound 12g) is a potent inhibitor of the bc1 complex, demonstrating fungicidal properties against cucumber downy mildew (CDM).</p>Formule :C16H22N6O5S2Couleur et forme :SolidMasse moléculaire :442.51320S Proteasome-IN-4
CAS :<p>20S Proteasome-IN-4: brain-penetrant, parasite-specific, oral, inhibits T.b. brucei proteasome (IC50: 6.3nM), for HAT research.</p>Formule :C20H18ClF2N3O3Couleur et forme :SolidMasse moléculaire :421.83QPX7728 methoxy acetoxy methy ester
CAS :<p>QPX7728 methoxy acetoxy methy ester is an inhibitor of boronic acid β-lactamase.</p>Formule :C14H14BFO7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :324.07Jun13296
CAS :<p>Jun13296 is an orally active quinoline SARS-CoV-2 papain-like protease inhibitor (IC50 = 0.13 µM, Ki = 8.8 nM). It demonstrates potent inhibitory effects against SARS-CoV-2 variants and Nirmatrelvir-resistant mutants. Jun13296 reduces lung viral titers and prevents lung tissue damage in SARS-CoV-2 infection models.</p>Formule :C30H34N6OCouleur et forme :SolidMasse moléculaire :494.631KKL-40
CAS :<p>KKL-40 is a small-molecule inhibitor that targets the trans-translation process, effectively suppressing methicillin-sensitive and resistant Staphylococcus aureus (S. aureus) and other Gram-positive pathogens, including vancomycin-resistant Enterococcus faecium, Bacillus subtilis, and Streptococcus pyogenes. It works in synergy with the human antimicrobial peptide LL-37 to inhibit S. aureus, but does not show synergistic effects with other antibiotics such as daptomycin, kanamycin, or erythromycin. KKL-40 inhibits trans-translation, an extreme form of recoding, while being non-toxic to HeLa cells.</p>Formule :C16H9F4N3O2Couleur et forme :SolidMasse moléculaire :351.255VPC-80051
CAS :<p>VPC-80051 is an hnRNP A1 splicing activity inhibitor that directly interacts with the hnRNP A1 RBD and reduces AR-V7 messenger levels in the 22Rv1 CRPC cell line. VPC-80051 is applicable in prostate cancer research.</p>Formule :C16H13F2N3OCouleur et forme :SolidMasse moléculaire :301.291Atramycin A
CAS :<p>Atramycin A is an anthraquinone antibiotic with antitumor properties.</p>Formule :C25H24O9Couleur et forme :SolidMasse moléculaire :468.453Ganaplacide hydrochloride
CAS :<p>Ganaplacide hydrochloride (KAF156 HCl) is an orally administered imidazopyrimidine antimalarial agent that inhibits Plasmodium PI4K activity.</p>Formule :C22H24ClF2N5ODegré de pureté :93.97%Couleur et forme :SoildMasse moléculaire :447.91ZK-806450
CAS :<p>ZK-806450 is a compound with antiviral properties. It exhibits high binding potential to the allosteric site of the SARS-CoV-2 3CL protease and is capable of specific and stable interaction with the GAG site of the dengue virus envelope protein.</p>Formule :C31H31N5OCouleur et forme :SolidMasse moléculaire :489.611Antibacterial agent 112
<p>Compound 112: Powerful antibacterial, MIC 1250 μM against B. subtilis, E. coli, E. faecalis, S. typhimurium, S. aureus; also an HIV-1 antibody.</p>Formule :C35H23N5O5Couleur et forme :SolidMasse moléculaire :593.59GHP-88309
CAS :<p>GHP-88309 is an orally active, broad-spectrum anti-paramyxovirus agent that targets viral polymerase, interrupting viral RNA synthesis. It effectively inhibits respiratory syncytial virus (RSV), measles virus (MeV), and canine distemper virus (CDV) with an EC50 of 0.06-1.2 μM. In mouse models, GHP-88309 demonstrates significant anti-infective activity.</p>Formule :C16H11FN2OCouleur et forme :SolidMasse moléculaire :266.27FPI-1465
CAS :<p>FPI-1465: Dual serine-β-lactamase & PBP inhibitor; IC50 PBP2=1.0 μg/mL; Kd CTX-M-15=0.011μM, OXA-48=5.3μM.</p>Formule :C11H18N4O7SCouleur et forme :SolidMasse moléculaire :350.35Antibacterial agent 262
CAS :<p>Antibacterialagent 262 (compound A23) is a potent antibacterial agent that inhibits the activity of Xanthomonas oryzae pv oryzae. It also disrupts the integrity of bacterial cell membranes by preventing the formation of biofilms of Xanthomonas oryzae pv oryzae.</p>Formule :C17H18F2N6O4S3Couleur et forme :SolidMasse moléculaire :504.554LN-439A
CAS :<p>LN-439A (compound LN-439A) is a novel BAP1 inhibitor that suppresses the growth of basal-like breast cancer by degrading KLF5.</p>Formule :C24H26FN3O4Couleur et forme :SolidMasse moléculaire :439.48Antifungal agent 17
<p>Antifungal agent 17 showed good antifungal activity against B. cinerea (EC50: 2.86 μg/mL).</p>Formule :C18H16Br2O2Couleur et forme :SolidMasse moléculaire :424.135-Iminodaunorubicin hydrochloride
CAS :<p>5-Iminodaunorubicin HCl: quinone-modified anthracycline with antitumor properties, induces DNA breaks in cancer cells.</p>Formule :C27H31ClN2O9Couleur et forme :SolidMasse moléculaire :563.00Finafloxacin
CAS :<p>Finafloxacin is a pH-activated fluoroquinolone, most effective at pH 5.0-6.0, targeting bacterial topoisomerases, used for UTIs and H. pylori infections.</p>Formule :C20H19FN4O4Couleur et forme :SolidMasse moléculaire :398.39MRL-494
<p>MRL-494, a small-molecule BamA inhibitor, resists efflux and outer membrane permeability, with antibacterial properties.</p>Formule :C26H35FN16O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :622.66LasR-IN-3
<p>LasR-IN-3 inhibits LasR in Pseudomonas, disrupting its dimer, causing loss of function.</p>Formule :C22H19N3O2Couleur et forme :SolidMasse moléculaire :357.41SP inhibitor 1
<p>SP inhibitor 1 blocks SARS-CoV-2 replication in vitro (0.3250<5.98 μM) and targets SP protein (IC50: 3.26 μM) with antiviral effects.</p>Formule :C36H38N2O2Couleur et forme :SolidMasse moléculaire :530.7RAD51-IN-7
CAS :<p>RAD51-IN-7 inhibits RAD51 gene, with potential for mitochondrial disorders. (From WO2021164746A1, cmpd 71)</p>Formule :C25H31N5O4S2Couleur et forme :SolidMasse moléculaire :529.67Antitubercular agent-23
<p>Antitubercular agent-23 combats Candida albicans (MIC: 1.1 μg/ml) and M. tuberculosis (MIC: 1 μg/ml).</p>Formule :C20H22FN5O8SCouleur et forme :SolidMasse moléculaire :511.48Cefempidone
CAS :<p>Cefempidone (GR 50692) is a third-generation cephalosporin antibiotic. It exhibits antibacterial activity by inhibiting penicillin-binding proteins involved in the synthesis of bacterial cell walls.</p>Formule :C22H21N7O6S2Masse moléculaire :543.58SARS 3CLpro-IN-1
CAS :<p>SARS 3CLpro-IN-1: stereospecific SARS 3CL protease inhibitor, octahydroisochromene class, IC50 = 95 μM.</p>Formule :C22H38N4O2Couleur et forme :SolidMasse moléculaire :390.56N-Cbz-L-Cysteine
CAS :<p>N-Cbz-L-Cysteine (Cbz-cysteine) (compound 5) functions as a potent inhibitor of β-lactamase II, exhibiting a K i value of 97 µM [1].</p>Formule :C11H13NO4SCouleur et forme :SolidMasse moléculaire :255.29Anti-MRSA agent 27
CAS :<p>Anti-MRSA agent 27 (compound 4a) is a potent antimicrobial agent against methicillin-resistant Staphylococcus aureus (MRSA) with a minimum inhibitory concentration (MIC) of 0.0975 μmol/L. It effectively disrupts MRSA biofilms and inhibits the production of hemolysins.</p>Formule :C15H10F3N3OSCouleur et forme :SolidMasse moléculaire :337.32Acetomycin
CAS :<p>Acetomycin, a γ-lactone from S. ramulosus, halts HCT-8 colon and L1210 leukemia cell growth.</p>Formule :C10H14O5Couleur et forme :SolidMasse moléculaire :214.22NS2B/NS3-IN-3
CAS :<p>NS2B/NS3-IN-3 (Compd 66) is an inhibitor of Flavivirus NS2B-NS3 protease [1] .</p>Formule :C19H21N3O2Couleur et forme :SolidMasse moléculaire :323.39Tuberculosis inhibitor 5
<p>Compound 11i: potent, non-toxic anti-tuberculosis biphenyl analogue.</p>Formule :C25H18N2O2SCouleur et forme :SolidMasse moléculaire :410.49WRN inhibitor 11
CAS :<p>WRN inhibitor 11 (Example 17) is an orally effective inhibitor of WRN helicase, with an IC50 of 63 nM.</p>Formule :C34H35ClF3N9O5Couleur et forme :SolidMasse moléculaire :742.15SARS-CoV-2-IN-100
CAS :<p>SARS-CoV-2-IN-100 (Compound 172) is a broad-spectrum antiviral agent against various SARS-CoV-2 variants. It works synergistically with Nirmatrelvir to reduce the risk of antiviral resistance.</p>Formule :C29H23NO2Couleur et forme :SolidMasse moléculaire :417.50Antifungal agent 11
<p>Antifungal agent 11 has a good antifungal effect.</p>Formule :C21H19F2N7O3S2Couleur et forme :SolidMasse moléculaire :519.55Cilastatin ammonium salt
CAS :<p>Cilastatin ammonium salt is an antibiotic that is particularly effective against Gram-positive cocci, with a half-life of 3-4 hours.</p>Formule :C16H29N3O5SCouleur et forme :SolidMasse moléculaire :375.48Gallinamide A
CAS :<p>Gallinamide A is a potent inhibitor of cathepsin L with an IC 50 value of 17.6 pM.</p>Formule :C31H52N4O7Couleur et forme :SolidMasse moléculaire :592.77Cefamandole lithium
CAS :<p>Cefamandole (lithium), a second-generation broad-spectrum cephalosporin antibiotic, exhibits antimicrobial activity. Upon metabolism in the body, it releases free NMTT, which can lead to hypoprothrombinemia.</p>Formule :C18H17LiN6O5S2Couleur et forme :SolidMasse moléculaire :468.44Metallo-β-lactamase-IN-16
CAS :<p>Metallo-β-lactamase-IN-16 (compound 18), a sulfone-containing metallo-β-lactamase inhibitor, exhibits antimicrobial activity. It effectively inhibits various metallo-β-lactamases, including NDM-1 (New Delhi metallo-β-lactamase-1), IMP-1 (imipenemase-1), VIM-1 (Verona Integron-encoded Metallo-β-lactamase), and VIM-2. The IC50 values for these enzymes are 0.16 nM, 0.23 nM, 0.31 nM, and 1.0 nM respectively.</p>Formule :C16H16N8O4S3Couleur et forme :SolidMasse moléculaire :480.54Polθ-IN-6
CAS :<p>Polθ-IN-6 (Compound 89) is an inhibitor of DNA polymerase theta (Polθ) and exhibits antitumor activity.</p>Formule :C25H23N3O3SCouleur et forme :SolidMasse moléculaire :445.53SARS-CoV-2 Mpro-IN-34
<p>SARS-CoV-2 Mpro-IN-34 (Compound 26) acts as an inhibitor of SARS-CoV-2 Mpro with an IC50 of 6 nM. It also inhibits OC43 Mpro, demonstrating an IC50 of 33 nM. Furthermore, this compound exhibits antiviral activity in Vero E6 cells infected with SARS-CoV-2, with an EC50 of 0.103 μM.</p>Formule :C30H37Cl2N5O3Couleur et forme :SolidMasse moléculaire :586.55MTH1 activator-1
CAS :<p>MTH1 activator-1 is an MTH1 activator that enhances endogenous MTH1 activity and significantly reduces 8-oxo-dG levels in cellular DNA. It is useful for investigating the upregulation of oxidative damage repair in nucleotide pools and examining biological effects, as well as for studies aiming to delay or prevent tumorigenesis.</p>Formule :C29H23F3N4O2Couleur et forme :SolidMasse moléculaire :516.514WRN inhibitor 12
CAS :<p>WRN inhibitor 12 (compound 5) serves as an inhibitor for the WRN helicase.</p>Formule :C33H33ClF3N9O5Couleur et forme :SolidMasse moléculaire :728.12Anthelvencin A
CAS :<p>Anthelvencin A is a pyrrolylamide metabolite with moderate antibacterial and anthelmintic activity.</p>Formule :C19H25N9O3Couleur et forme :SolidMasse moléculaire :427.46Antifungal agent 42
<p>Antifungal 42 blocks biofilm formation and inhibits C.albicans' CYP51.</p>Formule :C22H20Cl2N4Se2Couleur et forme :SolidMasse moléculaire :569.25TREX1-IN-4
CAS :<p>TREX1-IN-4 (Compound 96) is an inhibitor of TREX1 and TREX2, exhibiting an IC50 of less than 0.1 μM for TREX1 and an IC50 of less than 1 μM for TREX2. It has an EC50 ranging from 0.1 to 10 μM in HCT116 cells. TREX1-IN-4 is applicable for research in the field of cancer.</p>Formule :C24H19ClN6O4Couleur et forme :SolidMasse moléculaire :490.898PIQ-2
CAS :<p>PIQ-2 (compound 54) serves as an antiprotozoal agent, displaying potent activity against IP. falciparum 3D7 and B. divergens Rouen, with IC50 values of 9.4 nM and 1.6 nM, respectively.</p>Formule :C23H21F3N4O3Couleur et forme :SolidMasse moléculaire :458.43SPB07935
CAS :<p>SPB07935 inhibits plasmepsin II in the malaria-causing parasite Plasmodium falciparum and serves as an antimalarial agent. It affects the life cycle of P. falciparum, hindering the growth of the parasite's FcB1 and 3D7 strains, with IC50 values of 8 μM and 4.7 μM, respectively.</p>Formule :C22H15N5O4S2Couleur et forme :SolidMasse moléculaire :477.516RmlA-IN-2
<p>RmlA-IN-2: Strong RmlA blocker, hinders l-rhamnose synthesis & alters bacterial wall permeability (IC50: 0.303 μM).</p>Formule :C22H26BrN5O4SCouleur et forme :SolidMasse moléculaire :536.44HPH-15
CAS :<p>HPH-15 is an anti-cell migration compound that inhibits cell movement by binding to hnRNP U or suppressing TGF-β. Additionally, it prevents epithelial-to-mesenchymal transition (EMT). HPH-15 holds potential for research in areas such as anti-tumor metastasis and anti-fibrosis.</p>Formule :C19H31N3S4Couleur et forme :SolidMasse moléculaire :429.73SARS-CoV-2-IN-102
CAS :<p>SARS-CoV-2-IN-102 (example 58) is an inhibitor of the SARS-CoV papain-like protease (SARS-CoVPLpro), demonstrating an IC50 of less than 100 nM.</p>Formule :C29H34F2N6O2Couleur et forme :SolidMasse moléculaire :536.62Antifungal agent 113
CAS :<p>Antifungalagent 113 (compound 9a) serves as an effective antifungal and antibacterial agent. It exhibits strong inhibitory activity against both S. aureus and methicillin-resistant S. aureus.</p>Formule :C23H20O5Couleur et forme :SolidMasse moléculaire :376.40TREX1-IN-3
CAS :<p>TREX1-IN-3 (Compound 95) is an inhibitor of TREX1 and TREX2, with an IC50 of less than 0.1 μM for TREX1 and less than 1 μM for TREX2, as well as an EC50 of less than 1 μM for HCT116 cells. It is applicable for research in the field of cancer.</p>Formule :C24H19ClN6O4Couleur et forme :SolidMasse moléculaire :490.898Arohynapene B
CAS :<p>Arohynapene B is an anticoccidial compound that inhibits the growth of Eimeria parasites.</p>Formule :C18H22O3Couleur et forme :SolidMasse moléculaire :286.366HRSV/HMPV-IN-1
CAS :<p>HRSV/HMPV-IN-1 (compound 3) is an inhibitor targeting HRSV/HMPV, exhibiting EC50 values of < 0.2 μM against human RSV-A and < 0.5 μM for human MPV A2 TN/94-49. This compound is utilized in the study of bronchiolitis and pneumonia.</p>Formule :C34H31ClF2N4O5SCouleur et forme :SolidMasse moléculaire :681.15Neuraminidase-IN-18
CAS :<p>Neuraminidase-IN-18 (compound N5), a novel polyheterocyclic neuraminidase (NA) inhibitor, demonstrates significant inhibitory activity against H5N1 NA, with an IC 50 of 0.14 μM against the wild-type H5N1 NA and 0.27 μM against the H5N1-H274Y mutant NA. This compound effectively binds to NAs, inhibiting influenza virus replication at the cellular level [1].</p>Formule :C22H18FN3O3SCouleur et forme :SolidMasse moléculaire :423.46Antibacterial agent 266
CAS :<p>Antibacterialagent 266 (Compound C5) is an inhibitor of plant pathogenic bacteria that disrupts the integrity of bacterial cell membranes. It exhibits an EC50 of 24.1 μg/mL against Xanthomonasoryzaepvoryzae (Xoo) and 39.0 μg/mL against X. axonopodispvcitri (Xac). Antibacterialagent 266 is valuable for research in plant pathology and the development of agricultural antibacterial agents.</p>Formule :C13H11N3OCouleur et forme :SolidMasse moléculaire :225.2462,5-Di-tert-butyl-1,4-benzoquinone
CAS :<p>2,5-Di-tert-butyl-1,4-benzoquinone is a potent antibacterial agent found primarily in marine Streptomyces sp. VITVSK1, effective against emerging antibiotic resistance. Additionally, it serves as a powerful inhibitor of RNA polymerase.</p>Formule :C14H20O2Couleur et forme :SolidMasse moléculaire :220.31Aurachin C
CAS :<p>Aurachin C is a quinoline alkaloid belonging to the isoprenoid class, known for its antimalarial, antifungal, and antibacterial properties. It acts as a selective terminal oxidase inhibitor.</p>Formule :C25H33NO2Couleur et forme :SolidMasse moléculaire :379.535Diclosulam
CAS :<p>Diclosulam (XDE 564) is an herbicide with a Ki value of less than 32 nM. It exhibits a MIC of 6.25 and 12.5 μM, and a MIC50 of 1.40 and 3.01 μM against the CBS10913 and CBS12373 strains, respectively.</p>Formule :C13H10Cl2FN5O3SCouleur et forme :SolidMasse moléculaire :406.22T-2513 hydrochloride
CAS :<p>T-2513 hydrochloride: selective topoisomerase I inhibitor, binds DNA complex, halts DNA/RNA synthesis, causes cell death.</p>Formule :C25H28ClN3O5Couleur et forme :SolidMasse moléculaire :485.96NDM-1 inhibitor-7
CAS :<p>NDM-1 inhibitor-7 (Compound A8) is an NDM-1 inhibitor with an IC50 of 10.284 μM. It restores the ability of meropenem (MEM) to penetrate the cell wall of Gram-negative bacteria and effectively reinstates MEM's antibacterial activity against NDM-1 positive Escherichia coli. Moreover, NDM-1 inhibitor-7 demonstrates significant efficacy in both Galleria mellonella and murine peritonitis infection models.</p>Formule :C9H10N2OS2Couleur et forme :SolidMasse moléculaire :226.319DC-159a
CAS :<p>DC-159a, an 8-methoxy fluoroquinolone, possesses broad-spectrum antibacterial activity, with a particular efficacy against Gram-positive pathogens. The MIC90 values for DC-159a are 0.5 μg/mL against Streptococcus anginosus group, 4 μg/mL against Clostridium difficile, and 2 μg/mL against Bacteroides fragilis.</p>Formule :C21H23F2N3O40·5H2OCouleur et forme :SolidMasse moléculaire :428.4295KWR095
CAS :<p>KWR095 is an orally active inhibitor of WRN, demonstrating an IC50 of 0.032 μM against WRN ATPase. It disrupts the double-stranded helicase activity of WRN and inhibits tumor cell proliferation, exhibiting antitumor properties.</p>Formule :C33H31ClF3N9O4Couleur et forme :SolidMasse moléculaire :710.105Anticaries agent-1
CAS :<p>Anticaries agent-1 (Compound 21b) is utilized as an anticaries agent. It effectively inhibits biofilm formation with an IC50 of 77 μM and restricts the growth of S. mutans.</p>Formule :C15H12O4Couleur et forme :SolidMasse moléculaire :256.253MED6-189
CAS :<p>MED6-189, an analog of kalihinol, disrupts the apicoplast functions and vesicular transport in the malignant malaria parasite (P. falciparum, IC50 < 50 nM). The compound specifically targets the apicoplast, which is a non-photosynthetic plastid essential for isoprenoid synthesis, found in most apicomplexan parasites.</p>Formule :C17H26N2OCouleur et forme :SolidMasse moléculaire :274.40SLU-10906
CAS :<p>SLU-10906 (Compound 63) is an orally active inhibitor of Cryptosporidium. It demonstrates activity against the parasite in cell-based infection models with an EC50 of 0.19 μM and exhibits no cytotoxicity. SLU-10906 is a promising candidate for research in cryptosporidiosis.</p>Formule :C22H21BFN5O2Couleur et forme :SolidMasse moléculaire :417.244NEU-1017
CAS :<p>NEU-1017 serves as a broad-spectrum antiparasitic compound, effectively inhibiting T. brucei, L. major, and P. falciparum with EC50 values of 210 nM, 240 nM, and 3 nM, respectively.</p>Formule :C33H31ClFN5O3SCouleur et forme :SolidMasse moléculaire :632.147ABT-072
CAS :<p>ABT-072 is a nonnucleoside NS5B polymerase inhibitor and a candidate drug evaluated for treatment of hepatitis C virus.</p>Formule :C24H27N3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :469.55Arterolane
CAS :<p>Arterolane is an antimalarial compound. For against P. falciparum Ro73 and W2, the IC50s are both 1.1 nM.</p>Formule :C22H36N2O4Couleur et forme :SolidMasse moléculaire :392.53(R)-ZG197
<p>(R)-ZG197: Activates Sa ClpP (EC50=1.5μM) & Hs ClpP (EC50=31.4μM); selective for Sa ClpP.</p>Formule :C28H35F3N4O3Couleur et forme :SolidMasse moléculaire :532.6Antibacterial agent 62
<p>Novel anti-TB agent 62 is a redox compound with bactericidal activity against active and dormant bacteria.</p>Formule :C24H33BrN2O2Couleur et forme :SolidMasse moléculaire :461.44HSV-TK substrate
CAS :<p>HSV-TK substrate is a substrate for HSV-TK with antitumor activity. It induces multi-log cytotoxicity in HSV-TK-expressing and bystander cells.</p>Formule :C11H15N5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :281.27MI-1851
CAS :<p>MI-1851 is a potent peptidomimetic inhibitor. MI-1851could prevent proteolytic processing of the S protein from SARSCoV-2 by endogenous furin in HEK293 cells.</p>Formule :C34H53N15O6Couleur et forme :SolidMasse moléculaire :767.88ZINC4497834
CAS :<p>ZINC4497834 is an inhibitor of the main protease Mpro of SARS-CoV-2. It is utilized in research targeting the treatment of COVID-19.</p>Formule :C18H19N5O3SCouleur et forme :SolidMasse moléculaire :385.44PLpro-IN-7
CAS :<p>PLpro-IN-7 (compound 83) is a novel papain-like protease (PLpro) inhibitor with an IC50 of 3 nM.</p>Formule :C30H34ClN7OCouleur et forme :SolidMasse moléculaire :544.09HBV-IN-31
CAS :<p>HBV-IN-31: strong cccDNA inhibitor, anti-HBV, IC50=0.13 µM HBsAg, hampers cell growth.</p>Formule :C23H18ClNO6Couleur et forme :SolidMasse moléculaire :439.857-APRA
CAS :<p>7-APRA is a semisynthetic intermediate of the cephalosporin class of antibiotics. It exhibits antibacterial activity and is primarily used in the synthesis of other cephalosporin antibiotics, such as Cefaclor and Cefprozil.</p>Formule :C10H12N2O3SMasse moléculaire :240.28Glutamate-5-kinase-IN-2
<p>Glutamate-5-kinase-IN-2 (compound 54) is a potent G5K inhibitor with 4.2 μM MIC, potential in anti-TB research.</p>Formule :C17H10ClFN2Couleur et forme :SolidMasse moléculaire :296.73Griseofulvic Acid
CAS :<p>Griseofulvic Acid ((±)-Griseofulvic acid) is a metabolite of the antifungal agent Griseofulvin. It induces protein aggregation and tubulin polymerization in cell-free assays.</p>Formule :C16H15ClO6Masse moléculaire :338.74SARS-CoV-2 nsp14-IN-2
<p>SARS-CoV-2 nsp14-IN-2: Strong Nsp14 methyltransferase inhibitor (IC50: 0.09 μM), potential for COVID-19 research.</p>Formule :C21H21N5O5SCouleur et forme :SolidMasse moléculaire :455.49Ipronidazole
CAS :<p>Ipronidazole (RO-71554) is an orally effective antiprotozoal agent used to prevent and ameliorate histomoniasis in turkeys, commonly referred to as blackhead disease.</p>Formule :C7H11N3O2Couleur et forme :SolidMasse moléculaire :169.18cis-RdRP-IN-5
<p>Cis-RdRP-IN-5 is an effective inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), employed in influenza virus research.</p>Formule :C23H21N3O5Couleur et forme :SolidMasse moléculaire :419.43Antibacterial agent 78
<p>Antibacterial agent 78 (compound 30) is an antibacterial agent with improved cytotoxicity profile[1].</p>Formule :C16H23N3S2Couleur et forme :SolidMasse moléculaire :321.5Cap-dependent endonuclease-IN-5
CAS :<p>Cap-dependent endonuclease-IN-5 inhibits CEN and fights influenza with low toxicity and good in vivo properties.</p>Formule :C27H21F2N3O4S2Couleur et forme :SolidMasse moléculaire :553.60MsbA-IN-2
<p>MsbA-IN-2 is a potent inhibitor of the lipopolysaccharide transporter MsbA and is able to act on E. coli MsbA (IC50: 2 nM).</p>Formule :C23H19Cl2NO3Couleur et forme :SolidMasse moléculaire :428.31Antibiofilm agent-14
CAS :<p>Antibiofilm agent-14 (compound 11) functions as an antibiofilm agent. It exhibits antifungal activity against C.albicans SC5314, with a minimum inhibitory concentration (MIC) of 50 μM.</p>Formule :C26H30ClN3OCouleur et forme :SolidMasse moléculaire :435.989Antibacterial agent 82
<p>Antibacterial agent 82 (compound 7p) is an antibacterial agent [1].</p>Formule :C22H18N2O2Couleur et forme :SolidMasse moléculaire :342.39Palmitanilide
CAS :<p>Palmitanilide (Palmitic acid anilide) is an antimicrobial agent effective against Gram-positive bacteria. It can electrostatically bind to components of the cell wall of Gram-positive bacteria (such as Bacillus cereus), altering the membrane structure and affecting normal cellular functions. Palmitanilide shows potential for research into infections caused by Gram-positive bacteria.</p>Formule :C22H37NOCouleur et forme :SolidMasse moléculaire :331.535Antiviral agent 15
<p>Compound 15f, a Clofazimine derivative, inhibits rabies (EC50: 1.45 μM) and SARS-CoV-2 (EC50: 14.6 μM).</p>Formule :C27H24FN5OCouleur et forme :SolidMasse moléculaire :453.51Lentiginosine
CAS :<p>Lentiginosine is a selective amyloglucosidase inhibitor.</p>Formule :C8H15NO2Couleur et forme :SolidMasse moléculaire :157.21Cyclophilin inhibitor 1
CAS :<p>Cyclophilin inhibitor 1: orally available, Kd 5 nM, potent against HCV, EC50 for HCV 2a is 98 nM.</p>Formule :C31H39N5O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :593.67CDA-IN-4
CAS :<p>CDA-IN-4 (compound VS-24) is an inhibitor of chitin deacetylase (CDA). At a concentration of 100 μg/mL, CDA-IN-4 provides a protective effect of 61.2% against rice blast disease.</p>Formule :C10H9BrN4O2SCouleur et forme :SolidMasse moléculaire :329.17WQ3810 TFA
<p>WQ3810 TFA is an orally available fluoroquinolone with antimicrobial activity against Mycobacterium tuberculosis and inhibits the DNA rotamase activity of</p>Formule :C24H23F6N5O5Degré de pureté :99.52%Couleur et forme :SoildMasse moléculaire :575.46OUN58101
CAS :<p>OUN58101, also MDK-8101/BI-D, is an RSV L-protein inhibitor with no formal name, first reported in patent WO 2005042530.</p>Formule :C32H36N6O6Couleur et forme :SolidMasse moléculaire :600.66Ladirubicin
CAS :<p>Ladirubicin, as an anthracyclines analog is the leading compound of alkylcyclines.</p>Formule :C29H31NO11SCouleur et forme :SolidMasse moléculaire :601.62Antitubercular agent-16
<p>Compound 5q is a potent antitubercular with low MIC90 values (0.40-23.51 μg/mL) against M. tuberculosis strains, showing minimal cytotoxicity.</p>Formule :C21H27N3SCouleur et forme :SolidMasse moléculaire :353.52LpxC-IN-10
CAS :<p>LpxC-IN-10 is a selective LpxC inhibitor with an MIC of 0.5 μg/mL against E. coli and K. pneumoniae and is capable of being used to study bacterial infections.</p>Formule :C30H31N5O3Couleur et forme :SolidMasse moléculaire :509.6NS2B/NS3-IN-4
CAS :<p>Compound 34e inhibits DENV2/ZIKV proteases; IC50: 0.69 µM (DENV2), 1.04 µM (ZIKV).</p>Formule :C15H11NO4Couleur et forme :SolidMasse moléculaire :269.25Antibacterial agent 118
<p>Antibacterial agent 118, potent against various mycobacteria, has MIC values ranging from 10.2 to 163.0 μM. Useful in TB research.</p>Formule :C19H21N5O2SCouleur et forme :SolidMasse moléculaire :383.47XR8-69
<p>XR8-69 is a SARS-CoV-2 PLpro inhibitor. XR8-69 has a low micromolar antiviral effect in SARS-CoV-2 infected human cells.</p>Formule :C26H30N4O2SCouleur et forme :SolidMasse moléculaire :462.61DNDI-8219
CAS :<p>DNDI-8219 is an antitubercular agent. It has potent antileishmanial effects.</p>Formule :C13H10F3N3O5Couleur et forme :SolidMasse moléculaire :345.23HCV-IN-7
CAS :<p>HCV-IN-7: potent oral HCV NS5A inhibitor, pan-genotypic, IC50s 3-47 pM, good pharmacokinetics, favorable liver uptake.</p>Formule :C40H48N8O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :768.9212(S)-HETE
CAS :<p>Enpatoran hydrochloride (M5049 hydrochloride) is a TLR7/8 inhibitor with antiviral activity that is used in the study of autoimmune diseases.</p>Formule :C20H32O3Couleur et forme :SolidMasse moléculaire :320.47NS2B/NS3-IN-5
<p>Compound 25b inhibits DENV2/ZIKV NS2B/NS3 proteases; IC50: ZIKV 0.67μM, DENV2 4.38μM.</p>Formule :C14H9IN2O3SCouleur et forme :SolidMasse moléculaire :412.2Antifungal agent 43
<p>Antifungal agent 43 inhibits biofilms with low toxicity to human cancer cells.</p>Formule :C24H26N4Se2Couleur et forme :SolidMasse moléculaire :528.41Ciluprevir
CAS :<p>Ciluprevir is a selective HCV NS3 protease inhibitor, effective against non-genotype-1 HCV; less potent for genotypes 2/3.</p>Formule :C40H50N6O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :774.93Antibacterial agent 88
<p>Antibacterial agent 88 is an effective antibacterial agent against B. subtilis (MIC: 4 μg/ml) with MIC values of ≤0.0156 μg/mL for MRSA, MRSE and S. aureus.</p>Formule :C31H44N2O6SCouleur et forme :SolidMasse moléculaire :572.76Anti-MRSA agent 6
<p>Anti-MRSA agent 6 (compound 3q6) is a potent anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) agent with low cytoxicity for MCF-7, A549 cells [1].</p>Formule :C16H11F2N3Couleur et forme :SolidMasse moléculaire :283.28G247
<p>G247 inhibits MsbA by keeping NBDs apart, blocking ATPase activity.</p>Formule :C24H19Cl2FO3Couleur et forme :SolidMasse moléculaire :445.31SARS-CoV-2 PLpro-IN-1
CAS :<p>SARS-CoV-2 PLpro-IN-1 (Compound 85) is a non-covalent competitive inhibitor of SARS-CoV-2 PLpro with an IC50 value of 15.06 μM and a Ki value of 22.93 μM. It inhibits the proliferation of Vero cells, exhibiting an IC50 of 7.47 μM.</p>Formule :C18H19N5OCouleur et forme :SolidMasse moléculaire :321.376Amicoumacin A
CAS :<p>Amicoumacin A has antibacterial activity. It also strongly suppresses inflammatory and ulcer activity.</p>Formule :C20H29N3O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :423.46CRS-3123
CAS :<p>CRS-3123, a methionyl-tRNA synthetase inhibitor, is used potentially for the treatment of enteric infections.</p>Formule :C19H19Br2N3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :513.25MLEB-22043
<p>MLEB-22043 is a synthetic siderophore-monocyclic β-lactam conjugate which enters bacteria through TonB-dependent transport proteins utilizing its siderophore component, subsequently exerting antibacterial activity via its β-lactam portion. This compound acts as a broad-spectrum antibiotic, exhibiting significant inhibitory activity against pathogens such as Klebsiella pneumoniae, Escherichia coli, Acinetobacter baumannii, and Pseudomonas aeruginosa.</p>Formule :C25H25N9O11S2Couleur et forme :SolidMasse moléculaire :691.65Antifungal agent 19
<p>Antifungal agent 19 shows the potent antifungal activity ( EC 50 = 0.72 μM).</p>Formule :C19H18F4O2Couleur et forme :SolidMasse moléculaire :354.34Rubropunctatin
CAS :<p>Rubropunctatin is a monascus pigment with very potent cancer cell proliferation inhibitory effects.</p>Formule :C21H23NO4Couleur et forme :SolidMasse moléculaire :353.41Cap-dependent endonuclease-IN-17
CAS :<p>CEN inhibitor IN-17 targets influenza A/H3N2; IC50: 1.29 μM. From patent CN112898346A, DSC701.</p>Formule :C24H20F2N3O7PSCouleur et forme :SolidMasse moléculaire :563.47Xeruborbactam
CAS :<p>QPX7728 is an of ultra-broad-spectrum boronic acid beta-lactamase.</p>Formule :C10H8BFO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :221.98Pks13-TE inhibitor 4
CAS :<p>Pks13-TE inhibitor 4 (compound 44) is a potent inhibitor from the thiazole series that effectively targets Pks13 to combat tuberculosis (TB) and addresses drug resistance.</p>Formule :C26H25N5O6Masse moléculaire :503.51L-threo-β-Hydroxyaspartic acid
CAS :<p>L-threo-β-Hydroxyaspartic acid is an amino acid antibiotic with activity against Bacillus subtilis, Xanthomonas oryzae, Mycobacterium phlei, and Botrytis cinerea.</p>Formule :C4H7NO5Couleur et forme :SolidMasse moléculaire :149.102Antiviral agent 67
CAS :<p>Antiviralagent 67 (compound PC6) is an inhibitor of DENVNS5 (RNA-dependent RNA polymerase) with a Ki value of 1.12 nM.</p>Formule :C19H19N3OCouleur et forme :SolidMasse moléculaire :305.374MTI013
<p>MTI013 is a selective inhibitor of SARS-CoV-2 nsp14 Mtase (IC50: 2.98 µM) and an antiviral agent (IC50: 10.33 µM in HCoV-229E infected Huh7 cells). Additionally, MTI013 demonstrates synergistic antiviral effects when used in conjunction with the RdRp inhibitor SHEN26.</p>Formule :C24H26N6O4SCouleur et forme :SolidMasse moléculaire :494.57Antifungal agent 27
<p>Antifungal agent 27 shows moderate action against MRSA, weak against C. albicans, with MICs of 8 μg/mL and 32 μg/mL, respectively.</p>Formule :C18H23N5OSCouleur et forme :SolidMasse moléculaire :357.47LolCDE-IN-2
CAS :<p>LolCDE-IN-2 is a potent Lol protein (LolCDE) inhibitor. LolCDE-IN-2 shows antibacterial activity with a MIC of 2 μg/ml against E. coli MG1655 [1].</p>Formule :C22H17N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :367.40N-Nitrosonornicotine
CAS :<p>N-Nitrosonornicotine, a tobacco-specific nitrosamine, exhibits carcinogenic and mutagenic properties, and is capable of inducing micronuclei in C3A cells. Additionally, N-Nitrosonornicotine can form DNA adducts.</p>Formule :C9H11N3OCouleur et forme :SolidMasse moléculaire :177.2MT0703
CAS :<p>MT0703 is a cephalosporin antibiotic featuring an aminothiazolylglycyl moiety with a 1,5-dihydroxy-4-pyridinone-2-carbonyl group, displaying potent activity against Pseudomonas species.</p>Formule :C26H25N7O9S3Couleur et forme :SolidMasse moléculaire :675.71trans-Clopenthixol
CAS :<p>Trans-Clopenthixol ((E)-Clopenthixol) is an antibiotic without any sedative properties. It can be used in vitro to inhibit Pseudomonas aeruginosa and Plasmodium falciparum.</p>Formule :C22H25ClN2OSCouleur et forme :SolidMasse moléculaire :400.965MAY0132
CAS :<p>MAY0132 is a potent and selective EPAC2 inhibitor with an IC50 of 0.4 μM. It significantly inhibits the replication of HMPV, AdV, and RSV, reduces cytokine/chemokine production induced by viral infections, and suppresses NF-κB activation. MAY0132 exhibits antiviral activity and can be used in respiratory virus infection research.</p>Formule :C16H15ClF3NCouleur et forme :SolidMasse moléculaire :313.745SARS-CoV-2-IN-22
CAS :<p>SARS-CoV-2-IN-22 is a SARS-CoV-2 pseudovirus inhibitor (IC50: 16.96 μM).</p>Formule :C27H24N2O3SCouleur et forme :SolidMasse moléculaire :456.56RSV-IN-5
CAS :<p>RSV-IN-5: Dual inhibitor for RSV fusion proteins, effective on wild-type A2 and D486N mutant with EC50s of 2.0 nM & 8.1 nM. Potent anti-RSV.</p>Formule :C28H37N7O2Couleur et forme :SolidMasse moléculaire :503.64SMCypI C31
<p>SMCypIC31, a non-peptide cyclophilin inhibitor, blocks PPIase at 0.1 μM IC50 and fights various HCV genotypes (EC50: 1.20-7.76 μM).</p>Formule :C27H30N4O2SCouleur et forme :SolidMasse moléculaire :474.62Antibacterial agent 99
CAS :<p>Compound 7b (Antibacterial agent 99) is an effective agent with antibacterial, antifungal properties and no haemolytic activity.</p>Formule :C27H27BrN2Couleur et forme :SolidMasse moléculaire :459.42SARS-CoV-2-IN-106
CAS :<p>SARS-CoV-2-IN-106 (compound 19) is a SARS-CoV-2 papain-like protease inhibitor, displaying IC50 values of 0.44 μM for papain-like proteases and 0.18 μM for viral replication.</p>Formule :C31H38FN5O2Couleur et forme :SolidMasse moléculaire :531.66CM-728
CAS :<p>CM-728 is an oxazanonaphthoquinone that exhibits cytotoxic and antibacterial properties. It acts as a human peroxidase-1 inhibitor and serves as a source of oxidative stress affecting mitochondrial function.</p>Formule :C22H14N2O5Couleur et forme :SolidMasse moléculaire :386.357HIV-1 inhibitor-8
<p>HIV-1 inhibitor-8: potent oral NNRTI, low toxicity, IC50: 0.081 μM, effective on multiple strains, EC50: 4.44-54.5 nM.</p>Formule :C25H21N5OSCouleur et forme :SolidMasse moléculaire :439.53CB 30900
CAS :<p>CB30900 is a novel and effective thymidylate synthase inhibitor.</p>Formule :C31H32FN5O9Couleur et forme :SolidMasse moléculaire :637.61Erythromycin B
CAS :<p>Erythromycin B exhibits antimalarial activity by effectively inhibiting the asexual growth of Plasmodium falciparum.</p>Formule :C37H67NO12Couleur et forme :SolidMasse moléculaire :717.93Dencatistat
CAS :<p>Dencatistat is a highly selective and oral cytidine triphosphate synthase 1 CTPS1 inhibitor specific.CTPS1-IN-2 for B-cell, T-cell lymphomas and solid tumors.</p>Formule :C24H27N7O5SDegré de pureté :98.85%Couleur et forme :SolidMasse moléculaire :525.58DENV-IN-6
CAS :<p>DENV-IN-6, a potent anti-DENV (I-IV) and HIV-1 IIIB inhibitor with EC50 ranging 6.8-17.5 μM for DENV and EC50 0.0181 μM for HIV-1.</p>Formule :C23H26ClFN4OSCouleur et forme :SolidMasse moléculaire :461Elongation factor P-IN-2
<p>Elongation factor P-IN-2, a β-lysine derivative, is a potent EFP inhibitor reducing E. coli growth.</p>Formule :C16H35N3O2Couleur et forme :SolidMasse moléculaire :301.47DHX9-IN-19
CAS :<p>DHX9-IN-19 (compound 3) is an orally active inhibitor of DHX9, playing a significant role in cancer research.</p>Formule :C20H21ClN4O4S2Couleur et forme :SolidMasse moléculaire :480.988FGI-106
CAS :<p>FGI-106 combats Ebola, Rift Valley, Dengue Fever, HCV, and HIV-1; EC50s range from 100-900 nM.</p>Formule :C28H38N6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :458.64Antibacterial agent 278
CAS :<p>Antibacterialagent 278 (compound B1) is an antimicrobial agent that exhibits potent inhibitory activity against Gram-positive bacteria.</p>Formule :C24H17ClF2N4O3Couleur et forme :SolidMasse moléculaire :482.87Pneumolysin-IN-1
CAS :<p>Pneumolysin-IN-1 (compound PB-3), characterized as a targeted small molecule inhibitor of Pneumolysin (PLY) with an IC50 value of 3.1 µM, acts as a pore-blocking agent and an anti-virulence factor. This compound is useful for researching infections caused by Streptococcus pneumoniae [1].</p>Formule :C23H16Cl2N2O4Couleur et forme :SolidMasse moléculaire :455.29KPC-2-IN-2
<p>KPC-2-IN-2 (6c) inhibits KPC-2 enzyme in Klebsiella pneumoniae (Ki 0.038 μM) and boosts cefotaxime in E. coli KPC-2.</p>Formule :C12H10BN3O2SCouleur et forme :SolidMasse moléculaire :271.1PLP_Snyder530
<p>PLP_Snyder530, a potent PL pro inhibitor, halts SARS-CoV-2 by triggering protease conformation changes.</p>Formule :C24H24N2O2Couleur et forme :SolidMasse moléculaire :372.46Cetefloxacin
CAS :<p>Cetefloxacin (E 4868) is a broad-spectrum antibacterial antibiotic with a minimum inhibitory concentration (MIC) ranging from 0.007 to 8 µg/ml. In mice, cetefloxacin demonstrates favorable pharmacokinetic properties and provides protection against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae.</p>Formule :C20H16F3N3O3Masse moléculaire :403.35ZIKV-IN-4
<p>ZIKV-IN-4 is a low cytotoxic, acid-stable anti-ZIKV agent with an EC50 value of 3.49 μM. ZIKV-IN-4 exhibited potent inhibition of ZIKV NS5 MTase.</p>Formule :C33H37NO4Couleur et forme :SolidMasse moléculaire :511.65844-TFM
<p>844-TFM, a NBTI DNA gyrase blocker, IC50: 1.5 μM, kills Mycobacterium abscessus.</p>Formule :C24H25F3N4O2Couleur et forme :SolidMasse moléculaire :458.48AB25583
CAS :<p>AB25583 is a small molecule inhibitor of Polθ helicase (Polθ-hel) with an IC50 of 6 nM. It selectively kills cells deficient in BRCA1/2 and synergizes with Olaparib in cancer cells harboring pathogenic BRCA1/2 mutations. AB25583 can be utilized in tumor research.</p>Formule :C22H17ClN4O3SCouleur et forme :SolidMasse moléculaire :452.91HIV-IN-3
<p>HIV-IN-3 (Compound 22a) is a potent inhibitor of HIV (IC50: 1.5 μM). HIV-IN-3 has potential for the study of HIV-related diseases.</p>Formule :C21H32ClN7O3Couleur et forme :SolidMasse moléculaire :465.98Anti-MRSA agent 3
CAS :<p>Anti-MRSA agent 3 targets MRSA with 0.098 μg/ml MIC, low toxicity, binds DNA, and disrupts cell walls/membranes.</p>Formule :C29H18BrN3O2Couleur et forme :SolidMasse moléculaire :520.386Flutimide
CAS :<p>Flutimide: Endonuclease inhibitor, IC50 = 3μM, for research on acute respiratory diseases like influenza.</p>Formule :C12H18N2O3Couleur et forme :SolidMasse moléculaire :238.28Glasmacinal
CAS :<p>Glasmacinal is a non-antibacterial macrolide compound with anti-inflammatory activities.</p>Formule :C37H62N2O10Couleur et forme :SolidMasse moléculaire :694.90SARS-CoV-2-IN-6
<p>SARS-CoV-2-IN-6 is an inhibitor of SARS-CoV-2 3CLpro with the IC 50 value of 73 nM.</p>Formule :C17H13ClN2O2Couleur et forme :SolidMasse moléculaire :312.75Methyl 3-oxodecanoate
CAS :<p>Methyl 3-oxodecanoate exhibits virulence factor activity against human pathogens and shows effects on Synechococcus elongatus (a species of fluorescent algae) as well as on culture supernatant. Additionally, Methyl 3-oxodecanoate inhibits DNA synthesis by suppressing protein synthesis at the translation initiation level.</p>Formule :C11H20O3Couleur et forme :SolidMasse moléculaire :200.275KL-50
CAS :<p>KL-50, a selective toxin, effectively targets tumors deficient in the DNA repair protein O6-methylguanine-DNA-methyltransferase (MGMT), which corrects O6-alkylguanine lesions. This compound induces both DNA damage response pathways and cell cycle arrest in MGMT-deficient cells, regardless of mismatch repair (MMR) status. KL-50 shows promise in the study of brain tumors lacking MGMT.</p>Formule :C7H7FN6O2Couleur et forme :SolidMasse moléculaire :226.17GS-9822
CAS :<p>GS-9822 is a new LEDGIN inhibitor targeting LEDGF/p75 to alter HIV integration, showing a block-and-lock effect in cells.</p>Formule :C36H39ClN4O4SCouleur et forme :SolidMasse moléculaire :659.24BRL-42715
CAS :<p>BRL-42715 is an effective inhibitor of bacterial beta-lactamases.</p>Formule :C10H7N4NaO3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :286.24Saphenamycin
CAS :<p>Saphenamycin is an antibiotic from a strain of Streptomyces.</p>Formule :C23H18N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :402.40HIV-1 inhibitor-13
<p>HIV-1 inhibitor-13: oral NNRTI, IC50=0.14μM for HIV-1 RT, effective on resistant strains (EC50=2.85-18nM).</p>Formule :C30H32N6O3Couleur et forme :SolidMasse moléculaire :524.61Saussureamine C
CAS :<p>Saussureamine C is an inhibitor of H274Y and N294S mutants.</p>Formule :C19H26N2O5Couleur et forme :SolidMasse moléculaire :362.42HBV-IN-18
<p>HBV-IN-18 (Compound 3) is an HBV capsid assembly modulator (CpAM) (EC50: 2790 nM).</p>Formule :C17H15F6N5O2Couleur et forme :SolidMasse moléculaire :435.32Carbodine
CAS :<p>Carbodine is an antiviral targeting CTP synthetase, effective against influenza A0/PR-8/34 and A2/Aichi/2/68.</p>Formule :C10H15N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :241.24
