Microbiologie/Virologie
Les inhibiteurs en microbiologie et virologie sont des composés qui ciblent les microorganismes, y compris les bactéries, les virus et les champignons, perturbant leur croissance, leur réplication ou leur survie. Ces inhibiteurs sont essentiels pour étudier la pathogénie microbienne, comprendre les mécanismes de résistance et développer de nouvelles thérapies antimicrobiennes et antivirales. Les inhibiteurs de cette catégorie sont utilisés pour combattre les maladies infectieuses, explorer l'écologie microbienne et étudier les interactions hôte-pathogène. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en microbiologie et virologie pour soutenir vos recherches en maladies infectieuses, microbiologie et virologie.
Sous-catégories appartenant à la catégorie "Microbiologie/Virologie"
- Antibactérien(2.949 produits)
- Antibiotique(918 produits)
- Antifection(23 produits)
- DHFR(32 produits)
- Synthèse ADN/ARN(706 produits)
- VHB(176 produits)
- Protéase du VIH(447 produits)
- HSV(91 produits)
- Intégrase(2 produits)
- Ribosome(13 produits)
Affichez 2 plus de sous-catégories
5832 produits trouvés pour "Microbiologie/Virologie"
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Tuberculosis inhibitor 5
<p>Compound 11i: potent, non-toxic anti-tuberculosis biphenyl analogue.</p>Formule :C25H18N2O2SCouleur et forme :SolidMasse moléculaire :410.49Ambelline
CAS :<p>Ambelline has antitumor activity.</p>Formule :C18H21NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :331.36GTSE1-IN-1
CAS :<p>GTSE1-IN-1 (compound Y18), an orally active GTSE1 inhibitor, exhibits notable anticancer properties. It effectively represses the proliferation of cancer cells by downregulating GTSE1 transcription and expression, which leads to DNA damage and promotes persistent cell cycle arrest and cellular senescence. Moreover, GTSE1-IN-1 substantially reduces the adhesion, migration, and invasion of colorectal cancer HCT116 cells and non-small cell lung cancer A549 cells in vitro.</p>Formule :C21H24FN7Couleur et forme :SolidMasse moléculaire :393.46GR 122222X
CAS :<p>GR 122222X is an inhibitor of topoisomerase II.</p>Formule :C26H35N5O11SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :625.65Anthelvencin A
CAS :<p>Anthelvencin A is a pyrrolylamide metabolite with moderate antibacterial and anthelmintic activity.</p>Formule :C19H25N9O3Couleur et forme :SolidMasse moléculaire :427.46Cefclidin
CAS :<p>Cefclidin (Cefclidine) is a cephalosporin compound.</p>Formule :C21H26N8O6S2Couleur et forme :SolidMasse moléculaire :550.61117,17-Ethylendioxyandrost-5-en-3β-ol
CAS :<p>17,17-Ethylendioxyandrost-5-en-3β-ol, with an EC 50 of 629 μM, acts as an inhibitor of HSV-1. This compound is applicable in research studies focusing on viral infections.</p>Formule :C21H32O3Couleur et forme :SolidMasse moléculaire :332.48TREX1-IN-4
CAS :<p>TREX1-IN-4 (Compound 96) is an inhibitor of TREX1 and TREX2, exhibiting an IC50 of less than 0.1 μM for TREX1 and an IC50 of less than 1 μM for TREX2. It has an EC50 ranging from 0.1 to 10 μM in HCT116 cells. TREX1-IN-4 is applicable for research in the field of cancer.</p>Formule :C24H19ClN6O4Couleur et forme :SolidMasse moléculaire :490.898HBV-IN-48
CAS :<p>HBV-IN-48, an HBV inhibitor, exhibits potent antiviral activity against HBV in HepDE19 cells, demonstrated by its EC 50 value of 0.005 μM. Additionally, it effectively reduces serum HBV DNA levels in mouse models of HBV infection.</p>Formule :C22H15F4N3O3Couleur et forme :SolidMasse moléculaire :445.37GSK_WRN4
CAS :<p>GSK_WRN4 is a WRN helicase inhibitor with anti-cancer activity, inhibiting MSI tumor cell growth by inducing DNA double-strand breaks, useful in cancer research</p>Formule :C16H20N2O4SDegré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :336.41Cephalosporin C
CAS :<p>Cephalosporin C exhibits relatively weak resistance to Gram-positive and Gram-negative bacteria. It is stable against penicillinase, but can be decomposed by cephalosporinase. When hydrolyzed to remove its side chain, it yields 7-amino-cefenoic acid (7-ACA), which is an essential raw material for the production of semisynthetic cephalosporins.</p>Formule :C16H21N3O8SCouleur et forme :SolidMasse moléculaire :415.418RdRP-IN-4
<p>RdRP-IN-4, an oral arylbenzohydrazide, inhibits influenza A/B by targeting PB1 of RdRP, with EC50s of 53 nM (H1N1) and 20 nM (Flu B), and aids infected mice.</p>Formule :C17H17Br2N3O2Couleur et forme :SolidMasse moléculaire :455.14Antileishmanial agent-6
<p>Antileishmanial agent-6: potent against Leishmania donovani, IC50 0.54μM; cytotoxic IC50 10.2μM.</p>Formule :C24H26O8Couleur et forme :SolidMasse moléculaire :442.46PLpro-IN-6
CAS :<p>PLpro-IN-6 (compound 6) serves as an inhibitor for the papain-like protease (PLpro), demonstrating potent activity with an IC 50 of 0.019 μM against the SARS-CoV-2 PLpro enzyme.</p>Formule :C29H30N6OCouleur et forme :SolidMasse moléculaire :478.59SPB07935
CAS :<p>SPB07935 inhibits plasmepsin II in the malaria-causing parasite Plasmodium falciparum and serves as an antimalarial agent. It affects the life cycle of P. falciparum, hindering the growth of the parasite's FcB1 and 3D7 strains, with IC50 values of 8 μM and 4.7 μM, respectively.</p>Formule :C22H15N5O4S2Couleur et forme :SolidMasse moléculaire :477.516HPH-15
CAS :<p>HPH-15 is an anti-cell migration compound that inhibits cell movement by binding to hnRNP U or suppressing TGF-β. Additionally, it prevents epithelial-to-mesenchymal transition (EMT). HPH-15 holds potential for research in areas such as anti-tumor metastasis and anti-fibrosis.</p>Formule :C19H31N3S4Couleur et forme :SolidMasse moléculaire :429.73Colistin adjuvant-2
<p>Colistin adjuvant-2 is a compound that acts as a potentiation agent for colistin, effectively enhancing its activity against Gram-negative bacteria [1].</p>Formule :C14H7Cl2F3N2OCouleur et forme :SolidMasse moléculaire :347.12GC373
CAS :<p>GC373, an effective inhibitor of the SARS-CoV-2 M pro, impedes virus replication, exhibiting an inhibition concentration (IC 50) of 0.4 μM. This compound is valuable for use in anti-COVID-19 research.</p>Formule :C21H29N3O5Couleur et forme :SolidMasse moléculaire :403.47TREX1-IN-3
CAS :<p>TREX1-IN-3 (Compound 95) is an inhibitor of TREX1 and TREX2, with an IC50 of less than 0.1 μM for TREX1 and less than 1 μM for TREX2, as well as an EC50 of less than 1 μM for HCT116 cells. It is applicable for research in the field of cancer.</p>Formule :C24H19ClN6O4Couleur et forme :SolidMasse moléculaire :490.898Arohynapene B
CAS :<p>Arohynapene B is an anticoccidial compound that inhibits the growth of Eimeria parasites.</p>Formule :C18H22O3Couleur et forme :SolidMasse moléculaire :286.366Mycobacterium Tuberculosis-IN-6
CAS :<p>Mycobacterium Tuberculosis-IN-6 (compound b1) is an inhibitor of the enoyl reductase InhA from Mycobacterium tuberculosis, with an IC50 value of 7.74 μM. It is useful in antibacterial research.</p>Formule :C19H20FNOCouleur et forme :SolidMasse moléculaire :297.367Cefempidone
CAS :<p>Cefempidone (GR 50692) is a third-generation cephalosporin antibiotic. It exhibits antibacterial activity by inhibiting penicillin-binding proteins involved in the synthesis of bacterial cell walls.</p>Formule :C22H21N7O6S2Masse moléculaire :543.58Antibacterial agent 266
CAS :<p>Antibacterialagent 266 (Compound C5) is an inhibitor of plant pathogenic bacteria that disrupts the integrity of bacterial cell membranes. It exhibits an EC50 of 24.1 μg/mL against Xanthomonasoryzaepvoryzae (Xoo) and 39.0 μg/mL against X. axonopodispvcitri (Xac). Antibacterialagent 266 is valuable for research in plant pathology and the development of agricultural antibacterial agents.</p>Formule :C13H11N3OCouleur et forme :SolidMasse moléculaire :225.246Aurachin C
CAS :<p>Aurachin C is a quinoline alkaloid belonging to the isoprenoid class, known for its antimalarial, antifungal, and antibacterial properties. It acts as a selective terminal oxidase inhibitor.</p>Formule :C25H33NO2Couleur et forme :SolidMasse moléculaire :379.535Kinamycin B
CAS :<p>Kinamycin B is an antibacterial agent with anticancer activity.</p>Formule :C20H16N2O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :412.35NDM-1 inhibitor-7
CAS :<p>NDM-1 inhibitor-7 (Compound A8) is an NDM-1 inhibitor with an IC50 of 10.284 μM. It restores the ability of meropenem (MEM) to penetrate the cell wall of Gram-negative bacteria and effectively reinstates MEM's antibacterial activity against NDM-1 positive Escherichia coli. Moreover, NDM-1 inhibitor-7 demonstrates significant efficacy in both Galleria mellonella and murine peritonitis infection models.</p>Formule :C9H10N2OS2Couleur et forme :SolidMasse moléculaire :226.319KWR095
CAS :<p>KWR095 is an orally active inhibitor of WRN, demonstrating an IC50 of 0.032 μM against WRN ATPase. It disrupts the double-stranded helicase activity of WRN and inhibits tumor cell proliferation, exhibiting antitumor properties.</p>Formule :C33H31ClF3N9O4Couleur et forme :SolidMasse moléculaire :710.105SLU-10906
CAS :<p>SLU-10906 (Compound 63) is an orally active inhibitor of Cryptosporidium. It demonstrates activity against the parasite in cell-based infection models with an EC50 of 0.19 μM and exhibits no cytotoxicity. SLU-10906 is a promising candidate for research in cryptosporidiosis.</p>Formule :C22H21BFN5O2Couleur et forme :SolidMasse moléculaire :417.2447-APRA
CAS :<p>7-APRA is a semisynthetic intermediate of the cephalosporin class of antibiotics. It exhibits antibacterial activity and is primarily used in the synthesis of other cephalosporin antibiotics, such as Cefaclor and Cefprozil.</p>Formule :C10H12N2O3SMasse moléculaire :240.28NITD-688
CAS :<p>NITD-688 is a pan-serotype inhibitor targeting the dengue virus NS4B protein, effective through oral administration.</p>Formule :C25H32N4O3S2Couleur et forme :SolidMasse moléculaire :500.68Anti-MRSA agent 3
CAS :<p>Anti-MRSA agent 3 targets MRSA with 0.098 μg/ml MIC, low toxicity, binds DNA, and disrupts cell walls/membranes.</p>Formule :C29H18BrN3O2Couleur et forme :SolidMasse moléculaire :520.386Antiviral agent 15
<p>Compound 15f, a Clofazimine derivative, inhibits rabies (EC50: 1.45 μM) and SARS-CoV-2 (EC50: 14.6 μM).</p>Formule :C27H24FN5OCouleur et forme :SolidMasse moléculaire :453.51CDK9-IN-34
CAS :<p>CDK9-IN-34 (Compound 1b) is an inhibitor of CDK9 with an IC50 of 0.25 μM. It exhibits cytotoxicity against cancer cell lines HCT116, MCF7, and K652, with IC50 values of 1.43 μM, 3.01 μM, and 50.27 μM, respectively. Additionally, CDK9-IN-34 demonstrates antiviral activity against coronavirus 229E with an IC50 of 145.92 μM.</p>Formule :C18H20N4Couleur et forme :SolidMasse moléculaire :292.38Chitinase-IN-4
<p>Chitinase-IN-4 (compound 8f) is a potent and selective inhibitor of OfChi-h with an IC50 value of 0.1 μM and good insecticidal activity.</p>Formule :C21H24ClN7Couleur et forme :SolidMasse moléculaire :409.92WRN inhibitor 13
CAS :<p>WRN inhibitor 13 is an inhibitor of the WRN helicase with a pIC50 value ranging from 6 to 7.</p>Formule :C16H20N2O5SCouleur et forme :SolidMasse moléculaire :352.405SARS-CoV-2 Mpro-IN-25
CAS :<p>SARS-CoV-2 Mpro-IN-25 (Compound 3a) is a protease inhibitor for SARS-CoV-2, exhibiting an IC50 value of 0.26 μM. It demonstrates antiviral activity and is useful for research in the field of pneumonia.</p>Formule :C13H10FNO4Couleur et forme :SolidMasse moléculaire :263.22ACHN-975 TFA
CAS :<p>ACHN-975 TFA is a selective LpxC inhibitor with a subnanomolar inhibitory. It is against a wide range of gram-negative bacterias with low MIC values (≤1 μg/mL).</p>Formule :C22H24F3N3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :483.4377Carbodine
CAS :<p>Carbodine is an antiviral targeting CTP synthetase, effective against influenza A0/PR-8/34 and A2/Aichi/2/68.</p>Formule :C10H15N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :241.24Bleomycin Free Base
CAS :<p>Bleomycin Free Base, a glycopeptide antibiotic, halts DNA function and treats solid tumors.</p>Formule :C55H84N17O21S3Couleur et forme :SolidMasse moléculaire :1415.55Hyalodendrin
CAS :<p>Hyalodendrin ((+)-Hyalodendrin) acts as a fungal growth inhibitor, specifically targeting wood decay fungi. It exhibits low phytotoxicity and possesses an acute toxicity (LD50) level of 75 mg/kg in mice.</p>Formule :C14H16N2O3S2Couleur et forme :SolidMasse moléculaire :324.42LasR-IN-1
<p>LasR-IN-1 (9g) strongly inhibits LasR, potent vs E. coli, with a 28.13 μM MIC against P. aeruginosa.</p>Formule :C23H21N3O2Couleur et forme :SolidMasse moléculaire :371.43Antifungal agent 38
<p>Antifungal agent 38, a heterocyclic disulfide, shrinks hyphae and damages cell membranes, causing leakage.</p>Formule :C8H12N2S2Couleur et forme :SolidMasse moléculaire :200.32SARS-CoV-2-IN-82
CAS :<p>SARS-CoV-2-IN-82 (compound A) acts as an inhibitor of the Programmed-1 ribosomal frameshift (-1 PRF) in SARS-CoV-2 [1].</p>Formule :C18H18N2Couleur et forme :SolidMasse moléculaire :262.35Ro 24-4383
CAS :<p>Ro 24-4383 is a carbamate-linked dual-action antibacterial agent.</p>Formule :C32H31FN8O10S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :770.76BioA-IN-1
CAS :<p>BioA-IN-1 (Compound 15) is an inhibitor of the key enzyme BioA in the biotin biosynthesis pathway of Mycobacterium tuberculosis, with an IC50 value of 0.195 μM. It exhibits antibacterial activity without cytotoxicity.</p>Formule :C18H17NO3SCouleur et forme :SolidMasse moléculaire :327.397Antibacterial agent 99
CAS :<p>Compound 7b (Antibacterial agent 99) is an effective agent with antibacterial, antifungal properties and no haemolytic activity.</p>Formule :C27H27BrN2Couleur et forme :SolidMasse moléculaire :459.42Altersolanol A
CAS :<p>Altersolanol A (Stemphylin; NSC 173943) demonstrates effective antimicrobial properties, inhibiting the growth of Bacillus subtilis and Pseudomonas aeruginosa with a minimum inhibitory concentration (MIC) ranging from 25-100 μg/mL. Additionally, it shows no phytotoxic effects on Taxus at a concentration of 4 μg/μL.</p>Formule :C16H16O8Couleur et forme :SolidMasse moléculaire :336.29LY 215890
CAS :<p>LY 215890 is a compound that exhibits potent Gram-negative and Gram-positive antibacterial activity.</p>Formule :C13H12ClN5O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :385.78Plm IV inhibitor-2
CAS :<p>"Plm IV inhibitor-2: Potent for Plm IV (IC50=24nM), affects Plm II/Plm I; malaria research compound."</p>Formule :C39H54N4O4Couleur et forme :SolidMasse moléculaire :642.87Antibacterial agent 188
CAS :<p>Compound 2d (Antibacterial agent 188) serves as an antibacterial agent that suppresses the activity of dermatophytes [1].</p>Formule :C12H10N4SCouleur et forme :SolidMasse moléculaire :242.3
