Microbiologie/Virologie
Les inhibiteurs en microbiologie et virologie sont des composés qui ciblent les microorganismes, y compris les bactéries, les virus et les champignons, perturbant leur croissance, leur réplication ou leur survie. Ces inhibiteurs sont essentiels pour étudier la pathogénie microbienne, comprendre les mécanismes de résistance et développer de nouvelles thérapies antimicrobiennes et antivirales. Les inhibiteurs de cette catégorie sont utilisés pour combattre les maladies infectieuses, explorer l'écologie microbienne et étudier les interactions hôte-pathogène. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en microbiologie et virologie pour soutenir vos recherches en maladies infectieuses, microbiologie et virologie.
Sous-catégories appartenant à la catégorie "Microbiologie/Virologie"
- Antibactérien(2.949 produits)
- Antibiotique(918 produits)
- Antifection(23 produits)
- DHFR(32 produits)
- Synthèse ADN/ARN(706 produits)
- VHB(176 produits)
- Protéase du VIH(447 produits)
- HSV(91 produits)
- Intégrase(2 produits)
- Ribosome(13 produits)
Affichez 2 plus de sous-catégories
5832 produits trouvés pour "Microbiologie/Virologie"
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Neuraminidase-IN-11
<p>Neuraminidase-IN-11 (15e) inhibits H1N1 (IC50: 4.7nM), H5N1 (8.46nM), H5N8 viruses (1.5nM) selectively & potently.</p>Couleur et forme :SolidRAD51-IN-7
CAS :<p>RAD51-IN-7 inhibits RAD51 gene, with potential for mitochondrial disorders. (From WO2021164746A1, cmpd 71)</p>Formule :C25H31N5O4S2Couleur et forme :SolidMasse moléculaire :529.67ATIC-IN-2
CAS :<p>ATIC-IN-2 (Compound 1) is a competitive inhibitor of the bifunctional enzyme AICAR Tfase/IMPCH (ATIC), binding to inosine monophosphate cyclohydrolase (IMPCH) with a Ki of 0.13 μM.</p>Formule :C4H4N4O3SCouleur et forme :SolidMasse moléculaire :188.165NS2B/NS3-IN-4
CAS :<p>Compound 34e inhibits DENV2/ZIKV proteases; IC50: 0.69 µM (DENV2), 1.04 µM (ZIKV).</p>Formule :C15H11NO4Couleur et forme :SolidMasse moléculaire :269.25Chitin synthase inhibitor 11
<p>Potent CHS inhibitor with an IC50 of 0.10 mM; exhibits broad-spectrum antifungal properties.</p>Formule :C24H24N4O8Couleur et forme :SolidMasse moléculaire :496.47Anti-MRSA agent 3
CAS :<p>Anti-MRSA agent 3 targets MRSA with 0.098 μg/ml MIC, low toxicity, binds DNA, and disrupts cell walls/membranes.</p>Formule :C29H18BrN3O2Couleur et forme :SolidMasse moléculaire :520.386Pks13-TE inhibitor 4
CAS :<p>Pks13-TE inhibitor 4 (compound 44) is a potent inhibitor from the thiazole series that effectively targets Pks13 to combat tuberculosis (TB) and addresses drug resistance.</p>Formule :C26H25N5O6Masse moléculaire :503.515-Iminodaunorubicin hydrochloride
CAS :<p>5-Iminodaunorubicin HCl: quinone-modified anthracycline with antitumor properties, induces DNA breaks in cancer cells.</p>Formule :C27H31ClN2O9Couleur et forme :SolidMasse moléculaire :563.00Integrase-LEDGF/p75 allosteric inhibitor 1
CAS :<p>Oral HIV-1 allosteric integrase inhibitor, blocks DNA integration, antiviral, potent against NL432 (EC50: 3.9 nM).</p>Formule :C33H41NO6SCouleur et forme :SolidMasse moléculaire :579.75Epolactaene
CAS :<p>Epolactaene: neuritogenic, inhibits mammalian DNA polymerases & human DNA topoisomerase II.</p>Formule :C21H27NO6Couleur et forme :SolidMasse moléculaire :389.44BAS-118
CAS :<p>BAS-118 is a benzamide derivative exhibiting antibacterial activity. For 100 randomly selected strains of Helicobacter pylori, its MIC50, MIC90, and MIC range were ≤0.003, 0.013, and ≤0.003-0.025 mg/L, respectively. BAS-118 shows potential for research as an anti-H. pylori agent.</p>Formule :C20H18N2O2Couleur et forme :SolidMasse moléculaire :318.369MsbA-IN-1
<p>MsbA-IN-1: Potent MsbA inhibitor (IC50: 4 nM), anti-E. coli (MIC: 79 μM), penetrates Gram-negative bacteria.</p>Formule :C23H18Cl2FNO3Couleur et forme :SolidMasse moléculaire :446.3Cefamandole lithium
CAS :<p>Cefamandole (lithium), a second-generation broad-spectrum cephalosporin antibiotic, exhibits antimicrobial activity. Upon metabolism in the body, it releases free NMTT, which can lead to hypoprothrombinemia.</p>Formule :C18H17LiN6O5S2Couleur et forme :SolidMasse moléculaire :468.44L-697639
CAS :<p>L-697639 inhibits of HIV-1 reverse transcriptase and HIV-1 replication.</p>Formule :C18H21N3O2Couleur et forme :SolidMasse moléculaire :311.38NSC 641396
CAS :<p>NSC 641396 is a ribonucleotide reductase (RNR) inhibitor with an IC50 value of 1.2 μM. Additionally, it acts as an inhibitor of protein arginine N-methyltransferase 9 (PRMT9) and exhibits antitumor properties.</p>Formule :C18H13NO3Couleur et forme :SolidMasse moléculaire :291.301Chitinase-IN-5
<p>Chitinase-IN-5 (8i) blocks OfChi-h (IC50: 0.051 μM), has insecticidal qualities, useful for eco-friendly pest control.</p>Formule :C20H21ClFN7Couleur et forme :SolidMasse moléculaire :413.88trans-Clopenthixol
CAS :<p>Trans-Clopenthixol ((E)-Clopenthixol) is an antibiotic without any sedative properties. It can be used in vitro to inhibit Pseudomonas aeruginosa and Plasmodium falciparum.</p>Formule :C22H25ClN2OSCouleur et forme :SolidMasse moléculaire :400.965MurA-IN-6
CAS :<p>MurA-IN-6 (Compound L16) is a selective MurA inhibitor with an IC50 of 26.63 μM. It exhibits antibacterial activity by inhibiting the function of MurA, a key protein essential for bacterial cell wall synthesis.</p>Formule :C22H17N3O3SCouleur et forme :SolidMasse moléculaire :403.4548-Deazafolic acid
CAS :<p>8-Deazafolic acid inhibits folate-dependent bacteria S. faecium & L. casei, and fights lymphoid leukemia L1210 in mice.</p>Formule :C20H20N6O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :440.41AAA-10 formic
<p>AAA-10 formic is an orally active inhibitor of intestinal bacterial bile salt hydrolase (BSH) against B.</p>Formule :C26H43FO7SCouleur et forme :SolidMasse moléculaire :518.68Antitubercular agent-15
<p>Antitubercular agent-15 (5n): low toxicity, fights M. tuberculosis strains; MIC90 values range 0.73-18.8 μg/mL.</p>Formule :C21H29FN2Couleur et forme :SolidMasse moléculaire :328.47GRL-190-21
CAS :<p>GRL-190-21 (compound 5e), an inhibitor of SARS-Cov-2-Mpro, shows potent antiviral activity, with a K_i of 0.04 nM and an EC_50 of 0.26 μM in VeroE6 cells. It significantly reduces the infectivity, replication, and cytopathic effect of SARS-CoV-2 without notable toxicity [1].</p>Formule :C24H34F3N5O4Couleur et forme :SolidMasse moléculaire :513.55ALG-000184
CAS :<p>ALG-000184, a prodrug of the potent HBV capsid assembly modulator ALG-001075, shows potential for use in HBV infection research.</p>Formule :C23H20FN4Na2O8PCouleur et forme :SolidMasse moléculaire :576.3793HKT-IN-1
CAS :<p>3HKT-IN-1 (Compound 17122279) is an inhibitor of Anopheles gambiae 3-hydroxykynurenine transaminase (3HKT) and is utilized in malaria research.</p>Formule :C12H11BrN2O3Couleur et forme :SolidMasse moléculaire :311.131Antiviral agent 15
<p>Compound 15f, a Clofazimine derivative, inhibits rabies (EC50: 1.45 μM) and SARS-CoV-2 (EC50: 14.6 μM).</p>Formule :C27H24FN5OCouleur et forme :SolidMasse moléculaire :453.51AK-968-11563024
CAS :<p>AK-968-11563024 is an inhibitor targeting marine V. vulnificus NAT [(VIBVN)NAT] with an IC50 value of 18.86 µM. In V. vulnificus, NAT (aromatic amine N-acetyltransferase) plays a role in drug metabolism, contributing to drug resistance. Thus, AK-968-11563024 can be used for research related to drug tolerance.</p>Formule :C18H13I2N9O5Couleur et forme :SolidMasse moléculaire :689.162HCV-IN-38
<p>Potent oral HCV inhibitor HCV-IN-38 has 15 nM EC50, 431 SI, high efficacy, and low toxicity.</p>Formule :C22H24ClF3N4O4Couleur et forme :SolidMasse moléculaire :500.9MtMetAP1-IN-1
<p>MtMetAP1-IN-1 is an inhibitor of methionine aminopeptidase 1 ( MetAP1 ). MtMetAP1-IN-1 shows antimycobacterial activity.</p>Formule :C15H10BrN5O2SCouleur et forme :SolidMasse moléculaire :404.24A25822B
CAS :<p>A25822B is an antifungal agent.</p>Formule :C28H45NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :411.66Urease-IN-2
<p>Urease-IN-2 is a non-competitive inhibitor of urease (IC50: 0.94 μM, Ki: 1.6 μM) that non-competitively inhibits Jack bean urease (JBU).</p>Formule :C26H25N5O5S3Couleur et forme :SolidMasse moléculaire :583.7Antibacterial agent 79
<p>Antibacterial agent 79 is an antibacterial agent.</p>Formule :C18H27N3O2S3Couleur et forme :SolidMasse moléculaire :413.62Isopyrazam
CAS :<p>Isopyrazam, a plant protection product, exhibits potent antifungal activity. When applied to crops, it effectively inhibits the growth of various plant pathogenic fungi, significantly enhancing both the yield and quality of the crops. This compound demonstrates exceptional disease resistance capabilities in agricultural applications.</p>Formule :C20H23F2N3OCouleur et forme :SolidMasse moléculaire :359.41Antitubercular agent-29
<p>Compound 6xa inhibits drug-resistant tuberculosis with MICs 0.03 μg/mL for DS-Mtb and 0.03-0.06 for DR-Mtb, SI>40 for Vero cells.</p>Formule :C20H12ClN3O5Couleur et forme :SolidMasse moléculaire :409.78Antitrypanosomal agent 5
<p>Antitrypanosal agent 5 is a selective anti-trypanosomal agent that acts on T. brucei (IC50: 1 nM) and HEK293 cells (IC50: 483.3 μM).</p>Formule :C30H30N6O4SCouleur et forme :SolidMasse moléculaire :570.66EBOV-GP-IN-1
<p>EBOV-GP-IN-1 (Compound 28) is a potent inhibitor of Ebola entry, acting on the Ebola virus envelope glycoprotein (EBOV-GP) (IC50: 0.05 μM).</p>Formule :C25H40ClN3O2Couleur et forme :SolidMasse moléculaire :450.06CM-728
CAS :<p>CM-728 is an oxazanonaphthoquinone that exhibits cytotoxic and antibacterial properties. It acts as a human peroxidase-1 inhibitor and serves as a source of oxidative stress affecting mitochondrial function.</p>Formule :C22H14N2O5Couleur et forme :SolidMasse moléculaire :386.357Teslexivir
CAS :<p>Teslexivir is a topical antiviral agent that is an effective and selective inhibitor of the interaction between two essential viral proteins, E1 and E2.</p>Formule :C35H36BrN3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :642.58HBV-IN-18
<p>HBV-IN-18 (Compound 3) is an HBV capsid assembly modulator (CpAM) (EC50: 2790 nM).</p>Formule :C17H15F6N5O2Couleur et forme :SolidMasse moléculaire :435.32Anti-Trypanosoma cruzi agent-2
<p>Compd 3b: anti-trypanosomal, IC50 0.51 μM (NINOA), 3.06 μM (INC-5), also combats T. gondii.</p>Formule :C17H10ClNO5Couleur et forme :SolidMasse moléculaire :343.72DHX9-IN-19
CAS :<p>DHX9-IN-19 (compound 3) is an orally active inhibitor of DHX9, playing a significant role in cancer research.</p>Formule :C20H21ClN4O4S2Couleur et forme :SolidMasse moléculaire :480.988Griseofulvic Acid
CAS :<p>Griseofulvic Acid ((±)-Griseofulvic acid) is a metabolite of the antifungal agent Griseofulvin. It induces protein aggregation and tubulin polymerization in cell-free assays.</p>Formule :C16H15ClO6Masse moléculaire :338.743-Deazaguanosine
CAS :<p>3-Deazaguanosine (C3Guo) exhibits potent antiviral activity against SARS-CoV-2 with an EC50 of 1.14 μM and a CC50 greater than 200 μM in Vero E6 cells. It has the potential to prevent COVID-19.</p>Formule :C11H14N4O5Couleur et forme :SolidMasse moléculaire :282.25β-Glucuronidase-IN-2
<p>β-Glucuronidase-IN-2 is a potent inhibitor of E.</p>Formule :C21H17Cl3O7Couleur et forme :SolidMasse moléculaire :487.71Metesind Glucuronate
CAS :<p>Metesind Glucuronate is an antineoplastic. It also is a specific thymidylate synthase inhibitor.</p>Formule :C29H34N4O10SCouleur et forme :SolidMasse moléculaire :630.672'-Amino-2'-deoxyadenosine
CAS :<p>2'-Amino-2'-deoxyadenosine (9-(2-Amino-2-deoxypentofuranosyl)-9H-purin-6-amine) is a nucleoside antibiotic that effectively inhibits various Mycoplasma strains.</p>Formule :C10H14N6O3Masse moléculaire :266.26Enantiomer of Sofosbuvir
<p>Inactive enantiomer of Sofosbuvir, used for chronic hepatitis C; lacks reported biological activity.</p>Formule :C22H29FN3O9PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :529.45Meclocycline
CAS :<p>Meclocycline: a tetracycline antibiotic, inhibits LDH, reduces cell toxicity from mutant huntingtin, doesn't change protein levels in PC12 cells.</p>Formule :C22H21ClN2O8Couleur et forme :SolidMasse moléculaire :476.861,5-Dideoxy-1,5-imino-D-mannitol
CAS :<p>1,5-Dideoxy-1,5-imino-D-mannitol is an antibiotic with antibacterial properties.</p>Formule :C6H13NO4Couleur et forme :SolidMasse moléculaire :163.172GSK3739936
CAS :<p>GSK3739936 inhibits HIV-1 integrase (IC50: 11.1 nM, EC50: 1.7 nM), weak on CYP (IC50 >24.3 μM), rapid absorption, moderate clearance, high oral availability.</p>Formule :C34H43FN2O4Couleur et forme :SolidMasse moléculaire :562.71Avibactam sodium dihydrate
<p>Avibactam sodium dihydrate (NXL-104) is a reversible covalent inhibitor for CTX-M-15 and TEM-1 β-lactamases with IC50s of 5 nM and 8 nM.</p>Formule :C7H14N3NaO8SCouleur et forme :SolidMasse moléculaire :323.26
