Microbiologie/Virologie
Les inhibiteurs en microbiologie et virologie sont des composés qui ciblent les microorganismes, y compris les bactéries, les virus et les champignons, perturbant leur croissance, leur réplication ou leur survie. Ces inhibiteurs sont essentiels pour étudier la pathogénie microbienne, comprendre les mécanismes de résistance et développer de nouvelles thérapies antimicrobiennes et antivirales. Les inhibiteurs de cette catégorie sont utilisés pour combattre les maladies infectieuses, explorer l'écologie microbienne et étudier les interactions hôte-pathogène. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en microbiologie et virologie pour soutenir vos recherches en maladies infectieuses, microbiologie et virologie.
Sous-catégories appartenant à la catégorie "Microbiologie/Virologie"
- Antibactérien(3.296 produits)
- Antibiotique(937 produits)
- Antifection(26 produits)
- DHFR(34 produits)
- Synthèse ADN/ARN(793 produits)
- VHB(188 produits)
- Protéase du VIH(506 produits)
- HSV(96 produits)
- Intégrase(2 produits)
- Ribosome(13 produits)
Affichez 2 plus de sous-catégories
6367 produits trouvés pour "Microbiologie/Virologie"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
BRL-42715
CAS :BRL-42715 is an effective inhibitor of bacterial beta-lactamases.Formule :C10H7N4NaO3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :286.24GC373
CAS :GC373, an effective inhibitor of the SARS-CoV-2 M pro, impedes virus replication, exhibiting an inhibition concentration (IC 50) of 0.4 μM. This compound is valuable for use in anti-COVID-19 research.Formule :C21H29N3O5Couleur et forme :SolidMasse moléculaire :403.47LN002
CAS :LN002 is an orally active inhibitor of Cryptosporidium oxidase, utilized for research in cryptosporidiosis.Formule :C22H15N7Couleur et forme :SolidMasse moléculaire :377.40ONO-5334
CAS :ONO-5334: selective cathepsin K inhibitor, potential for osteoporosis study; Ki: 0.10 nM (human), 0.049 nM (rabbit), 0.85 nM (rat).Formule :C21H34N4O4SDegré de pureté :98.22% - 99.60%Couleur et forme :SolidMasse moléculaire :438.58Homer
CAS :Homer is a probe designed to target WD repeat domain 5 (WDR5). In MV4-11 cells, Homer induces the degradation of WDR5 with a half-maximal degradation concentration (DC50) of 53 nM. At a concentration of 1 µM, Homer decreases the protein levels of WDR5 in MV4-11 cells without affecting the mRNA levels that encode WDR5.Formule :C52H60F3N9O7SMasse moléculaire :1012.15Antimicrobial agent-29
CAS :Antimicrobial Agent-29 (Compound C35) influences the interaction between human hemoglobin and the Staphylococcus aureus IsdB hemophore. This compound facilitates the identification of IsdB:Hb PPI inhibitors [1].Formule :C19H14N4O4SCouleur et forme :SolidMasse moléculaire :394.4PFK-IN-1
CAS :PFK-IN-1 (compound 1) is an inhibitor of 6-phosphofructo-1-kinase (PFK), demonstrating IC50 values of 0.41 and 0.23 μM against T. brucei and T. cruzi PFK, respectively, and an ED50 of 15.18 μg/mL for T. brucei. The compound has a half-life of 9.7 minutes in rat liver microsomes and 408 minutes in mouse liver microsomes.Formule :C18H15Cl2N3O4SCouleur et forme :SolidMasse moléculaire :440.3HBV/HDV-IN-3
CAS :<p>HBV/HDV-IN-3 (Compd 1) acts as a dual inhibitor for HBV and HDV, demonstrating an efficacy (EC 50) below 50 nM against HBV .</p>Formule :C28H27BrF3N5O3Couleur et forme :SolidMasse moléculaire :618.44UNI418
CAS :<p>UNI418 is a dual inhibitor targeting PIKfyve and PIP5K1C, exhibiting antiviral activity against SARS-CoV-2 (EC50=1.4 μM). It inhibits the endocytosis of the virus mediated by ACE2 by suppressing PIP5K1C (IC50=60.1 nM; Kd=61 nM). Additionally, UNI418 impedes the entry of SARS-CoV-2 into host cells by inhibiting the proteolytic activation regulated by PIKfyve (Kd=0.78 nM).</p>Formule :C22H16N6Couleur et forme :SolidMasse moléculaire :364.40PLpro-IN-5
CAS :<p>PLpro-IN-5 (compound 21), serving as a PLPro protease inhibitor, boasts an IC50 of 91.14 nM. This compound exhibits a broad-spectrum antivirus efficacy, particularly effective against SARS-CoV, MERS-CoV, and SARS-CoV-2.</p>Formule :C26H33N3OCouleur et forme :SolidMasse moléculaire :403.56Antibacterial agent 172
CAS :Antibacterial Agent 172 (Compound 6a), a <i>Clostridioides difficile (Cd) SpoVD inhibitor with an IC50 value of 89 nM, effectively inhibits the sporulation of Clostridioides difficile. It is useful for research on bacterial infections [1].Formule :C21H21N9O5S2Couleur et forme :SolidMasse moléculaire :543.58Antibacterial agent 174
CAS :Compound 174 (Compound 5g), an antibacterial agent, exhibits potent anti-infective properties in vivo along with appreciable pharmacokinetic profiles. This highly active substance demonstrates favorable biofilm removal capabilities, low hemolysis, and acceptable mammalian cell toxicity [1].Formule :C25H30FN2NaO5Couleur et forme :SolidMasse moléculaire :480.5Antifungal agent 13
CAS :Antifungal agent 13 demonstrates significant antifungal activity against Sclerotinia sclerotiorum, achieving an EC50 of 1.25 mg/L.Formule :C21H16ClF3N4OCouleur et forme :SolidMasse moléculaire :432.83FIZ1 degrader 1
CAS :FIZ1 degrader 1 (compound 1) is an IMiD-based molecular glue degrader targeting FIZ1.Formule :C16H15N3O4Couleur et forme :SolidMasse moléculaire :313.31(Rac)-Plevitrexed
CAS :(Rac)-Plevitrexed is a racemate of Plevitrexed. Plevitrexed is an orally active and potent inhibitor of thymidylate synthase (TS).Formule :C26H25FN8O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :532.53Neocryptolepine-Cl
CAS :Neocryptolepine-Cl (compound Z24) is an inhibitor of Bcthi4, demonstrating excellent antifungal activity against B. cinerea, with an EC50 value of 0.56 μg/mL.Formule :C16H11ClN2Couleur et forme :SolidMasse moléculaire :266.725β-Glucuronidase-IN-2
β-Glucuronidase-IN-2 is a potent inhibitor of E.Formule :C21H17Cl3O7Couleur et forme :SolidMasse moléculaire :487.71Chitin synthase inhibitor 9
CHS inhibitor 9: a broad-spectrum antifungal for studying fungal infections.Formule :C24H25N3O6Couleur et forme :SolidMasse moléculaire :451.47A25822B
CAS :A25822B is an antifungal agent.Formule :C28H45NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :411.66NNRT-IN-2
CAS :NNRT-IN-2 (compound 7w) is an orally administered non-nucleoside reverse transcriptase inhibitor (NNRTI) that effectively suppresses both wild-type HIV-1 and various mutant strains. It inhibits HIV-1 reverse transcriptase with an EC 50 value of 22 nM. Additionally, NNRT-IN-2 exhibits insensitivity to CYP and hERG, demonstrating favorable safety and pharmacokinetic profiles [1].Formule :C19H14F3N5O3Masse moléculaire :417.34Anti-MRSA agent 27
CAS :Anti-MRSA agent 27 (compound 4a) is a potent antimicrobial agent against methicillin-resistant Staphylococcus aureus (MRSA) with a minimum inhibitory concentration (MIC) of 0.0975 μmol/L. It effectively disrupts MRSA biofilms and inhibits the production of hemolysins.Formule :C15H10F3N3OSCouleur et forme :SolidMasse moléculaire :337.32Chitin synthase inhibitor 1
Potent, selective CHS inhibitor with 0.12 mM IC50; effective against drug-resistant fungi.Formule :C22H20ClN3O3Couleur et forme :SolidMasse moléculaire :409.87BPR3P0128
CAS :BPR3P0128, a non-nucleoside RNA-dependent RNA polymerase (RdRp) inhibitor, is effective orally and can inhibit various SARS-CoV-2 variants. It exhibits EC 50 values of 0.62 µM for SARS-CoV-2 and 0.14 µM for HCoV-229E, demonstrating potent anti-pancoronavirus activity at submicromolar concentrations. Additionally, BPR3P0128 displays synergistic antiviral effects when used in combination with Remdesivir [1].Formule :C22H18BrN3O2Couleur et forme :SolidMasse moléculaire :436.30InhA-IN-7
CAS :<p>InhA-IN-7 (Compound 11), a derivative of Triclocan, shows inhibitory activity against enoyl-acyl carrier protein reductase (InhA) with an IC50 of 96 nM. It effectively inhibits the proliferation of both wildtype and mutant strains of Mycobacterium tuberculosis, exhibiting minimum inhibitory concentrations (MICs) ranging from 19 to 75 μM [1].</p>Formule :C17H18Cl2O2Couleur et forme :SolidMasse moléculaire :325.23Cefoxazole
CAS :Cefoxazole is a β-lactam antibiotic featuring an isoxazole structure, known for its antibacterial activity. It can be utilized in the study of infectious diseases.Formule :C21H18ClN3O7SCouleur et forme :SolidMasse moléculaire :491.902Diclosulam
CAS :Diclosulam (XDE 564) is an herbicide with a Ki value of less than 32 nM. It exhibits a MIC of 6.25 and 12.5 μM, and a MIC50 of 1.40 and 3.01 μM against the CBS10913 and CBS12373 strains, respectively.Formule :C13H10Cl2FN5O3SCouleur et forme :SolidMasse moléculaire :406.22JPL
CAS :JPL is an InhA-cofactor-ligand 3FNG inhibitor and is used for the study of tuberculosis [1].Formule :C19H20Cl2O2Couleur et forme :SolidMasse moléculaire :351.27Telinavir
CAS :Telinavir (SC-52151) is a potent and selective inhibitor of HIV protease. It effectively inhibits both HIV-1 and HIV-2, as well as lymphotropic, monocytotropic strains, and wild isolates of simian immunodeficiency viruses, with an EC50 of 26 ng/mL (43 nM). Telinavir shows high protein binding in human plasma and a low distribution rate in red blood cells.Formule :C33H44N6O5Couleur et forme :SolidMasse moléculaire :604.74LolCDE-IN-2
CAS :LolCDE-IN-2 is a potent Lol protein (LolCDE) inhibitor. LolCDE-IN-2 shows antibacterial activity with a MIC of 2 μg/ml against E. coli MG1655 [1].Formule :C22H17N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :367.40RSV-IN-5
CAS :RSV-IN-5: Dual inhibitor for RSV fusion proteins, effective on wild-type A2 and D486N mutant with EC50s of 2.0 nM & 8.1 nM. Potent anti-RSV.Formule :C28H37N7O2Couleur et forme :SolidMasse moléculaire :503.64Epiderstatin
CAS :Epiderstatin is isolated from Streptomyces pulveraceus subsp. epiderstagenes; inhibits mitogenic activity of epidermal growth factor.Formule :C15H20N2O4Couleur et forme :SolidMasse moléculaire :292.33Antibacterial agent 279
CAS :Antibacterialagent 279 (compound A12) is an effective antibacterial agent. It inhibits the SOS response of Pseudomonas aeruginosa.Formule :C9H11NO2SCouleur et forme :SolidMasse moléculaire :197.25SARS-CoV-2 Mpro-IN-31
CAS :SARS-CoV-2 Mpro-IN-31 (Compound 18) is an inhibitor of SARS-CoV-2 MPro with an IC50 of 11 nM. Additionally, this compound effectively inhibits the enzymatic activity of the cysteine proteases cathepsin B and cathepsin L, with IC50 values of 24 nM and 1.8 nM, respectively.Formule :C31H34Cl2N4O7Couleur et forme :SolidMasse moléculaire :645.53Polθ-IN-6
CAS :Polθ-IN-6 (Compound 89) is an inhibitor of DNA polymerase theta (Polθ) and exhibits antitumor activity.Formule :C25H23N3O3SCouleur et forme :SolidMasse moléculaire :445.53WRN inhibitor 12
CAS :WRN inhibitor 12 (compound 5) serves as an inhibitor for the WRN helicase.Formule :C33H33ClF3N9O5Couleur et forme :SolidMasse moléculaire :728.12PIQ-2
CAS :PIQ-2 (compound 54) serves as an antiprotozoal agent, displaying potent activity against IP. falciparum 3D7 and B. divergens Rouen, with IC50 values of 9.4 nM and 1.6 nM, respectively.Formule :C23H21F3N4O3Couleur et forme :SolidMasse moléculaire :458.43SARS-CoV-2 Mpro-IN-32
CAS :SARS-CoV-2 Mpro-IN-32 (Compound 1) is a selective inhibitor of SARS-CoV-2 MPro with an IC50 value of 230 nM. In vitro, it also inhibits the replication of various SARS-CoV-2 variants.Formule :C34H32Cl2N4O9Couleur et forme :SolidMasse moléculaire :711.54Insecticidal agent 16
CAS :Insecticidal agent 16 (compound A21) exhibits insecticidal activity against Plutella xylostella, with LC50 values of 1.2 and 13.2 µg/mL respectively.Formule :C21H13Cl2F6N5O2SCouleur et forme :SolidMasse moléculaire :584.32SARS-CoV-2 Mpro-IN-28
CAS :SARS-CoV-2 Mpro-IN-28 (Compound 1K) is an inhibitor of SARS-CoV-2 Mpro, exhibiting an EC50 of 24 μM.Formule :C14H17NO3SeCouleur et forme :SolidMasse moléculaire :326.25Polθ-IN-5
CAS :Polθ-IN-5 (Compound 139) is an inhibitor of DNA polymerase theta (Polθ) that exhibits antitumor activity.Formule :C23H18ClF2N7O3SCouleur et forme :SolidMasse moléculaire :545.95NNRT-IN-5
CAS :NNRT-IN-5 (compound 10d) is an orally available non-nucleoside reverse transcriptase (Reverse Transcriptase) inhibitor.Formule :C27H22N8Couleur et forme :SolidMasse moléculaire :458.52Anti-MRSA agent 6
Anti-MRSA agent 6 (compound 3q6) is a potent anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) agent with low cytoxicity for MCF-7, A549 cells [1].Formule :C16H11F2N3Couleur et forme :SolidMasse moléculaire :283.28N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide
N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide is a Ole1p desaturase inhibitor as well as antifungal agent [1].Formule :C11H9FN4OCouleur et forme :SolidMasse moléculaire :232.21Elongation factor P-IN-2
Elongation factor P-IN-2, a β-lysine derivative, is a potent EFP inhibitor reducing E. coli growth.Formule :C16H35N3O2Couleur et forme :SolidMasse moléculaire :301.47DENV-IN-6
CAS :DENV-IN-6, a potent anti-DENV (I-IV) and HIV-1 IIIB inhibitor with EC50 ranging 6.8-17.5 μM for DENV and EC50 0.0181 μM for HIV-1.Formule :C23H26ClFN4OSCouleur et forme :SolidMasse moléculaire :461Squalamine lactate
CAS :Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity.Formule :C37H71N3O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :718.04HIV-1 inhibitor-8
HIV-1 inhibitor-8: potent oral NNRTI, low toxicity, IC50: 0.081 μM, effective on multiple strains, EC50: 4.44-54.5 nM.Formule :C25H21N5OSCouleur et forme :SolidMasse moléculaire :439.5312(S)-HETE
CAS :<p>Enpatoran hydrochloride (M5049 hydrochloride) is a TLR7/8 inhibitor with antiviral activity that is used in the study of autoimmune diseases.</p>Formule :C20H32O3Couleur et forme :SolidMasse moléculaire :320.47Pol I-IN-1
Pol I-IN-1 is a powerful inhibitor of RNA polymerase I (Pol I), specifically targeting the large catalytic subunit RPA194, demonstrating an inhibitionFormule :C23H22N4O2Couleur et forme :SolidMasse moléculaire :386.45TCMDC-136230
TCMDC-136230 is a novel inhibitor of Plasmodium calcium kinetics with minimal inhibition of haemoglobin crystallisation.Formule :C24H34N4O2SCouleur et forme :SolidMasse moléculaire :442.62
