Neuroscience
Les inhibiteurs en neurosciences sont des composés conçus pour moduler l'activité de protéines, d'enzymes ou de récepteurs spécifiques au sein du système nerveux. Ces inhibiteurs sont cruciaux pour étudier les mécanismes moléculaires sous-jacents au fonctionnement neuronal, à la transmission synaptique et aux maladies neurodégénératives. En ciblant les récepteurs des neurotransmetteurs, les canaux ioniques et les voies de signalisation, les inhibiteurs en neurosciences facilitent l'exploration du fonctionnement cérébral et le développement de stratégies thérapeutiques pour des troubles neurologiques tels que la maladie d'Alzheimer, de Parkinson et l'épilepsie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs en neurosciences de haute qualité pour soutenir vos recherches en neurobiologie, neuropharmacologie et sciences cognitives.
Sous-catégories appartenant à la catégorie "Neuroscience"
- récepteur 5-HT(940 produits)
- ACK(1 produits)
- AChR(574 produits)
- ATP Citrate Lyase(16 produits)
- Récepteur adrénergique(2.939 produits)
- BACE(36 produits)
- Bêta-amyloïde(204 produits)
- CaMK(68 produits)
- COX(562 produits)
- Récepteur de la dopamine(407 produits)
- Récepteur GABA(336 produits)
- Gamma-sécrétase(59 produits)
- GluR(255 produits)
- GlyT(24 produits)
- Récepteur de l'histamine(358 produits)
- LRRK2(33 produits)
- Récepteur de la mélatonine(24 produits)
- NMDAR(28 produits)
- Récepteur OX(40 produits)
- Récepteur opioïde(296 produits)
Affichez 12 plus de sous-catégories
5400 produits trouvés pour "Neuroscience"
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COX-2-IN-33
<p>COX-2-IN-33 (compound 5f) is a selective COX-2 inhibitor with an IC50 value of 45.5 nM and exhibits potential as an anti-inflammatory agent.</p>Formule :C20H13ClF3N5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :479.8Guvacine hydrobromide
CAS :<p>Guvacine hydrobromide, an alkaloid derived from the Areca catechu nut, serves as a potent inhibitor of GABA (GABA uptakp) uptake.</p>Formule :C6H10BrNO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :208.05(R)-Citalopram oxalate
CAS :<p>(R)-Citalopram oxalate is a weak selective serotonin reuptake inhibitor (SSRI) that antagonises its S-isomer (escitalopram), anticonvulsant and antidepressant</p>Formule :C22H23FN2O5Degré de pureté :99.76%Couleur et forme :White SolidMasse moléculaire :414.43Hydroxytacrine maleate
CAS :<p>Hydroxytacrine maleate (Velnacrine maleate) is a cholinesterase inhibitor used in the study of Alzheimer's type dementia (SDAT).</p>Formule :C17H18N2O5Degré de pureté :98.84%Couleur et forme :SolidMasse moléculaire :330.34BSB
CAS :<p>BSB is a Congo red-derived fluorescent probe, an amyloid protein imaging agent, interacting with amyloid fibrils formed by Aβ (1-40) peptides in rodents.</p>Formule :C24H17BrO6Degré de pureté :95.53%Couleur et forme :SolidMasse moléculaire :481.29Binospirone
CAS :<p>Binospirone (MDL 73005EF) is a 5-HT1A receptor agonist with anxiolytic activity used in the study of movement disorders associated with neurologic dysfunction.</p>Formule :C20H26N2O4Degré de pureté :97.57% - 98.96%Couleur et forme :SoildMasse moléculaire :358.43Org 13011
CAS :<p>Org 13011 has CNS activity and induces conditioned taste aversion by mediating 5-HT 1A receptors.</p>Formule :C18H25F3N4ODegré de pureté :98.02%Couleur et forme :SoildMasse moléculaire :370.41Pridinol hydrochloride
CAS :<p>Pridinolhydrochloride is the hydrochloride form of Pridinol. Pridinol hydrochloride is an orally active anticholinergic agent, which can also be used as a muscle relaxant.</p>Formule :C20H26ClNOCouleur et forme :SolidMasse moléculaire :331.88γ-DGG TFA
CAS :<p>Gamma-DGG TFA is an antagonist of excitatory amino acids that can inhibit depolarization induced by NMDA, Kainate, and Quisqualate. In addition, it counteracts excitatory postsynaptic potentials (e.p.s.p.) in rat hippocampal slices.</p>Formule :C9H13F3N2O7Couleur et forme :SolidMasse moléculaire :318.24-hydroxy DiPT hydrochloride
CAS :<p>4-hydroxy DiPT (hydrochloride) is a 5-HT2A agonist that can induce head twitch response (HTR) in mice, indicating its hallucinogenic potential. This compound holds promise for research into hallucinogens.</p>Formule :C16H25ClN2OCouleur et forme :SolidMasse moléculaire :296.84AChE/BChE-IN-25
<p>AChE/BChE-IN-25 (Compound 6e) is an orally active inhibitor of hAChE and eqBChE, with IC50 values of 7.9 nM and 0.79 nM, respectively. This compound exhibits antioxidant activity, effective in scavenging free radicals with an IC50 of 22.91 μM. AChE/BChE-IN-25 demonstrates neuroprotective effects by reducing mitochondrial and cellular oxidative stress in a Drosophila Alzheimer's model and improves spatial and cognitive memory impairments induced by Scopolamine in mouse models.</p>Formule :C21H24ClN3O2Couleur et forme :SolidMasse moléculaire :385.89Trontinemab
CAS :<p>Trontinemab, a bispecific humanized IgG1-κ antibody, targets the amyloid beta A4 precursor protein (APP) and transferrin receptor p90, CD71 (TFRC).</p>Degré de pureté :96.77% - 99%Couleur et forme :LiquidAminoacetone hydrochloride
CAS :<p>Aminoacetone hydrochloride (1-Aminoacetone Hydrochloride) is an oxidative agent that induces loss of ferritin ferrireductase activity and iron uptake.</p>Formule :C3H8ClNODegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :109.56C18 L-erythro Ceramide (d18:1/18:0)
CAS :<p>C18 L-erythro Ceramide, a natural stereoisomer, inhibits rat brain mt-CDase with IC50 of 8.8 μM.</p>Formule :C36H71NO3Couleur et forme :SolidMasse moléculaire :565.95N-Desmethyl Pimavanserin
CAS :<p>N-Desmethyl Pimavanserin (AC-279) is the active metabolite of Pimavanserin and is used in the treatment of insomnia and other sleep disorders.</p>Formule :C24H32FN3O2Degré de pureté :98.02%Couleur et forme :SolidMasse moléculaire :413.53nAChR agonist 2
CAS :<p>Compound 8, identified as a selective alpha4beta2 (α4β2) neuronal acetylcholine receptor (nAChR) agonist, demonstrates a dissociation constant (Kd) of 26 nM,</p>Formule :C11H16N2Couleur et forme :SolidMasse moléculaire :176.263XL01126
<p>XL01126 degrades LRRK2 (DC50: 14 nM G2019S, 32 nM WT), crosses the blood-brain barrier, aiding Parkinson's studies.</p>Formule :C50H64ClFN10O6S2Couleur et forme :SolidMasse moléculaire :1019.69Maesopsin
<p>Maesopsin is a useful organic compound for research related to life sciences and the catalog number is T124581.</p>Formule :C15H12O6Couleur et forme :SolidMasse moléculaire :288.255Br-PBTC
CAS :<p>Br-PBTC modulates nAChRs; targets α2/β2,4 subtypes; potent with 0.1-0.6 μM EC50; binds α subunit c-tail.</p>Formule :C14H15BrN2OSCouleur et forme :SolidMasse moléculaire :339.25TC-2559 difumarate
CAS :<p>TC-2559 difumarate: Oral α4β2 nAChR partial agonist, CNS-selective, EC50 0.18 μM, prefers α4β2 over α2β4/α4β4/α3β4, antinociceptive.</p>Formule :C20H26N2O9Couleur et forme :SolidMasse moléculaire :438.43α-Casozepine
CAS :<p>α-Casozepine,Bioactive peptide from milk α-S1 casein. Binds GABA receptors. Anti-anxiety effects.</p>Formule :C60H94N14O16Couleur et forme :SolidMasse moléculaire :1267.47BChE-IN-12
CAS :<p>BChE-IN-12, non-competitive BChE inhibitor from Bletilla striata, IC50=2.3μM; potential Alzheimer’s research.</p>Formule :C31H30O5Couleur et forme :SolidMasse moléculaire :482.575-Hydroxymethyl tolterodine formate
CAS :<p>5-Hydroxymethyl tolterodine (formate) (PNU-200577 (formic)) is an active metabolite of the muscarinic acetylcholine receptor antagonists Tolterodine and Fesoterodine. It is synthesized by the cytochrome P450 (CYP) isoenzyme CYP2D6 and plasma esterases.</p>Formule :C23H33NO4Couleur et forme :SolidMasse moléculaire :387.51COX-1/2-IN-9
<p>COX-1/2-IN-9 (Compound 3n) serves as a selective and potent inhibitor of both COX-1 and COX-2, demonstrating IC 50 values of 0.031 µM for COX-1 and 0.01 µM for COX-2. This compound exhibits antibacterial and anti-inflammatory properties, effectively targeting MRSA 1478 (MIC=50 μg/mL) and multidrug-resistant S. lentus (MIC=50 μg/mL). Furthermore, COX-1/2-IN-9 shows promise in relieving MRSA-induced pneumonia in conditions of compromised immunity.</p>Formule :C30H20IN9O13S2Couleur et forme :SolidMasse moléculaire :905.57β-Amyloid (1-11)
CAS :<p>Anionic interaction of Beta-amyloid (1-11) with Factor XII is suspected to cause massive activation of the C4 (complement 4) system in the cerebrospinal fluid</p>Formule :C56H76N16O22Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1325.3Ebiratide TFA
<p>Ebiratide (HOE-427) TFA is a derivative of ACTH4-9 that exerts its effect directly on the central nervous system, enhancing memory. Ebiratide TFA also promotes the metabolism of acetylcholine (ACh) in the rat brain.</p>Formule :C48H73N11O10S·xC2HF3O2Couleur et forme :SolidMasse moléculaire :996.23 (free base)Triazolomethylindole-3-acetic acid
CAS :<p>Triazolomethylindole-3-acetic acid is a metabolite of Rizatriptan, which acts as an agonist for the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D.</p>Formule :C13H12N4O2Couleur et forme :SolidMasse moléculaire :256.26Pseudocoptisine acetate
CAS :<p>Pseudocoptisine acetate is a quaternary alkaloid isolated from the tubers of Corydalis turtschaninovii,with anti-inflammatory properties.</p>Formule :C21H17NO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :379.36COX-2-IN-46
<p>COX-2-IN-46 (compound 5m) serves as a potent anti-inflammatory and analgesic agent. It demonstrates a significant inhibitory action on COX-2, with an IC 50 value of 87.74 nM.</p>Formule :C28H19F2N3SCouleur et forme :SolidMasse moléculaire :467.53β-Amyloid (18-28)
CAS :<p>Intracerebroventricular administration of synthetic peptides Beta-amyloid (12-20), (12-28), and (18-28) causes amnesia in mice.</p>Formule :C55H81N13O18Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1212.31Cevimeline hydrochloride hemihydrate
CAS :<p>Cevimeline hydrochloride hemihydrate is a novel muscarinic receptor agonist, used as a candidate therapeutic drug for xerostomia in Sjogren's syndrome.</p>Formule :C20H38Cl2N2O3S2Degré de pureté :97.00%Couleur et forme :SolidMasse moléculaire :489.55TAT-CN21
<p>TatCN21, with an IC 50 of 77 nM, serves as a potent and selective inhibitor peptide of the calcium/calmodulin-dependent protein kinase II (CaMKII), a ubiquitously-expressed multifunctional serine/threonine protein kinase. It is particularly useful in research pertaining to ischemia and neurodegenerative diseases.</p>Formule :C169H303N69O43Couleur et forme :SolidMasse moléculaire :3989.65Dual AChE-MAO B-IN-3
<p>Compound C10 is a potent dual AChE/MAO-B inhibitor with IC50s of 0.58μM (AChE) and 0.41μM (MAO-B), useful in Alzheimer's research.</p>Formule :C30H26F3NO3Couleur et forme :SolidMasse moléculaire :505.53Echimidine N-oxide
CAS :<p>Echimidine N-oxide, a pyrrolizidine alkaloid, exhibits significant inhibitory activity against acetylcholinesterase (AChE) with an IC50 value of 0.347 mM.</p>Formule :C20H31NO8Couleur et forme :SolidMasse moléculaire :413.467α-Conotoxin EI
CAS :<p>Selective antagonist of neuromuscular nicotinic receptors α1β1γδ</p>Formule :C83H125N27O27S5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2093.37COX-1-IN-2
<p>COX-1-IN-2 (compound 5h) serves as a potent anti-inflammatory and analgesic agent. This compound demonstrates a significant inhibitory effect on COX-1, with an IC 50 value of 38.76 nM.</p>Formule :C29H22FN3OSCouleur et forme :SolidMasse moléculaire :479.57Paecilomide
CAS :<p>Paecilomide is a pyridone alkaloid and acetylcholinesterase inhibitor [1] .</p>Formule :C12H15NO4Couleur et forme :SolidMasse moléculaire :237.25AChE/BChE-IN-11
CAS :<p>AChE/BChE-IN-11, natural from artichoke leaves, inhibits AChE and BChE (IC50: 70/71 μM) for Alzheimer's research.</p>Formule :C21H22O12Couleur et forme :SolidMasse moléculaire :466.39BSBM6
CAS :<p>BSBM6 is an inhibitor of Aβ aggregation and neuronal toxicity that acts by reversing the aggregation and toxicity of amyloid-β peptides.</p>Formule :C23H29N3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :427.49Dicloromezotiaz
CAS :<p>Dicloromezotiaz: Potent insecticide targeting nAChRs, controls various lepidoptera.</p>Formule :C19H12Cl3N3O2SCouleur et forme :SolidMasse moléculaire :452.74Methyllycaconitine citrate
CAS :<p>Methyllycaconitine citrate (MLA) is an α7 neuronal nicotinic acetylcholine receptor (α7nAChR) antagonist that crosses the blood-brain barrier.</p>Formule :C43H58N2O17Degré de pureté :98.03% - 98.91%Couleur et forme :SolidMasse moléculaire :874.92Multitarget AD inhibitor-1
CAS :<p>Multitarget AD inhibitor-1: reversible, selective BuChE blocker, inhibits β-secretase and amyloid/tau aggregation, promising for Alzheimer's research.</p>Formule :C29H38N2OCouleur et forme :SolidMasse moléculaire :430.636β-Amyloid (29-40)
CAS :<p>β-Amyloid (29-40) is a fragment of Amyloid-β peptide.Alzheimer's beta amyloid peptide (29-40/42) C-terminal fragments have physical and chemical properties</p>Formule :C49H88N12O13SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1085.36Pirimiphos-ethyl
CAS :<p>Pirimiphos-ethyl is used as an organophosphorus pesticide.</p>Formule :C13H24N3O3PSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :333.39hAChE/hBuChE-IN-1
<p>hAChE/hBuChE-IN-1 (compound C2) acts as a dual inhibitor of cholinesterases, exhibiting IC50 values of 514 nM for hAChE and 358 nM for hBuChE. It is orally active and capable of enhancing cognitive function and spatial memory.</p>Formule :C30H31FN2O3Couleur et forme :SolidMasse moléculaire :486.577nAChR modulator-1
CAS :<p>nAChR modulator-1, a insecticide, is a insect nAChR orthosteric modulator [1] .</p>Formule :C12H8ClN3O2Couleur et forme :SolidMasse moléculaire :261.66AC1-IN-1
CAS :<p>AC1-IN-1 is a selective inhibitor of adenylyl cyclase type 1 (AC1, IC50 = 0.54 µM).</p>Formule :C18H18FN5O2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :355.37BChE-IN-10
CAS :<p>BChE-IN-10, a strong mixed BChE inhibitor (IC50=6.4 μM), comes from Bletilla striata for AD research.</p>Formule :C23H20O5Couleur et forme :SolidMasse moléculaire :376.4γ-Secretase modulator 10
CAS :<p>γ-Secretase modulator 10 is a novel γ-secretase modulator.</p>Formule :C25H23F3N4O2Couleur et forme :SolidMasse moléculaire :468.48AChE/BuChE-IN-6
<p>AChE/BuChE-IN-6 (Compound 11f) is an inhibitor of AChE and BuChE, with IC50 values of 1.24 and 1.85 μg/mL, respectively. It exhibits strong DPPH radical scavenging activity (IC50 = 3.15 μg/mL). In vivo toxicity studies demonstrate that AChE/BuChE-IN-6 is safe, showing no significant differences in blood and biochemical parameters compared to controls, and no abnormalities in liver and kidney tissues. This compound shows potential for Alzheimer's disease research.</p>Formule :C24H20ClN3O3Couleur et forme :SolidMasse moléculaire :433.887MGS0274
CAS :<p>MGS0274, a lipophilic prodrug of mGlu2/3 agonist MGS0008, enhances oral bioavailability, potentially aiding schizophrenia research.</p>Formule :C21H32FNO7Couleur et forme :SolidMasse moléculaire :429.485Bencycloquidium Bromide
CAS :<p>Bencycloquidium bromide is an M3 muscarinic antagonist that reduces nasal secretion in allergic rhinitis and has high affinity for M3 receptors.</p>Formule :C21H32BrNO2Couleur et forme :SolidMasse moléculaire :410.39Navicixizumab
CAS :<p>Navicixizumab, a bispecific VEGF/DLL4 inhibitor, pairs with Paclitaxel in ovarian and other cancer research.</p>Couleur et forme :LiquidR 50595
CAS :<p>R 50595 is a selective non-competitive cisapride antagonist.</p>Formule :C30H35Cl2F2N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :594.52FRM-024
CAS :<p>FRM-024 is a powerful gamma secretase modulator with the ability to penetrate the central nervous system (CNS), designed specifically for the treatment of</p>Formule :C22H22ClN5O2Couleur et forme :SolidMasse moléculaire :423.9JH-XII-03-02
CAS :<p>JH-XII-03-02 is a potent and selective leucine-rich repeat kinase 2 (LRRK2) proteolysis targeting chimera (PROTAC) degrader, utilized in Parkinson's Disease (PD</p>Formule :C43H51N9O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :853.92Perlapine
CAS :<p>Perlapine is an effective and selective HM3DQ DREADD agonist (EC50 = 2.8 nM).</p>Formule :C19H21N3Couleur et forme :SolidMasse moléculaire :291.39TRV-7019
CAS :<p>TRV-7019: BBB-permeable radioligand for brain imaging, used in diagnosing amyloid diseases, MS, and brain tumors.</p>Formule :C14H12INO3Couleur et forme :SolidMasse moléculaire :369.15Malaoxon
CAS :<p>Malaoxon is used as an insecticide.</p>Formule :C10H19O7PSCouleur et forme :SolidMasse moléculaire :314.29Millmerranone A
<p>Millmerranone A shows the acetylcholinesterase inhibitory property.</p>Formule :C27H28O9Couleur et forme :SolidMasse moléculaire :496.51Cinanserin hydrochloride
CAS :<p>Cinanserin hydrochloride (SQ 10643) is a 5-HT2 receptor blocker (Ki: 41 nM) and SARS-CoV 3C-like protease inhibitor.</p>Formule :C20H25ClN2OSDegré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :376.94Dehydrodiscretamine chloride
CAS :<p>Dehydrodiscretamine chloride, a dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), exhibits IC50 values of 17.8 μM and 118.8 μM,</p>Formule :C19H18ClNO4Couleur et forme :SolidMasse moléculaire :359.8(S)-3,4-DCPG
CAS :<p>(S)-3,4-DCPG ((S)-3,4-Dicarboxyphenylglycine) is a selective agonist of human metabotropic glutamate receptor 8a (mGluR8a).</p>Formule :C10H9NO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :239.18(-)-Coclaurine hydrochloride
CAS :<p>(-)-Coclaurine hydrochloride is an antagonist of nAChRs isolated from Sarcopetalum harveyanum.</p>Formule :C17H20ClNO3Degré de pureté :99.07%Couleur et forme :SoildMasse moléculaire :321.8LP 12 hydrochloride
CAS :<p>LP 12 hydrochloride is a selective 5-HT7 receptor agonist (Ki=0.13 nM).</p>Formule :C32H40ClN3OCouleur et forme :SolidMasse moléculaire :518.14RuBi-GABA
CAS :<p>Ruthenium-bipyridine-triphenylphosphine caged GABA</p>Formule :C42H39F6N5O2P2RuDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :922.81H-Indole-3-carboxylic acid, 5-[2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propoxy]-2-methyl-1-(4-methylphenyl)-, ethyl ester
CAS :<p>Compound 5936-0108对β-淀粉样蛋白可能具有调节作用。</p>Formule :C26H34N2O7Degré de pureté :99.44%Couleur et forme :SoildMasse moléculaire :486.565-HT6R antagonist 1
<p>Compound 8 (5-HT6R antagonist 1), a 5-HT6R antagonist (K i : 5 nM), not only demonstrates inhibition of platelet aggregation and excellent metabolic stability</p>Formule :C17H22F2N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :364.39Anabaseine
CAS :<p>Anabaseine is a broad nicotinic agonist, favoring alpha-7 AChRs in muscle/brain, and weakly stimulates alpha-4 beta-2 nAChRs.</p>Formule :C10H12N2Couleur et forme :SolidMasse moléculaire :160.224-Methoxyphenyl isothiocyanate
CAS :<p>4-Methoxyphenyl isothiocyanate (4-Methylphenyl ITC) is recognized as an antioxidant demonstrating an IC50 of 1.25 mM for scavenging DPPH free radicals. Its antioxidant capacity, as shown by the ORAC test, is 11.7 mM TE, equivalent to the efficacy of 11.7 mmol Trolox under similar conditions. Additionally, it extends the oxidation process in the Briggs–Rauscher reaction by approximately 9180 seconds. The compound also exhibits moderate cholinesterase inhibitory activity, with an inhibition rate of 30.4% for acetylcholinesterase (AChE) and 17.9% for butyrylcholinesterase (BChE). Research suggests 4-Methoxyphenyl isothiocyanate holds promise for applications in antioxidant and neurological disorder studies.</p>Formule :C8H7NOSCouleur et forme :SolidMasse moléculaire :165.21CALP2
CAS :<p>CALP2 is a CaM antagonist blocking EF-hand/Ca2+ site; inhibits CaM phosphodiesterase, raises Ca2+, and activates alveolar macrophages.</p>Formule :C68H104N14O13SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1357.72Lu AE51090
CAS :<p>Lu AE51090 is a selective muscarinic M1 receptor agonist with minimal off-target effects, receptor function and selective pharmacological modulation.</p>Formule :C24H29N3O3Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :407.51LY836
<p>LY836 is an orally active, neuroprotective compound that effectively inhibits the PSD95-nNOS association in cortical neurons.</p>Degré de pureté :98%Couleur et forme :Odour SolidMAO-B-IN-4
<p>MAO-B-IN-4 (Compound 26) is a reversible monoamine oxidase B (MAO-B) inhibitor with potent in vitro activity, characterized by an IC50 value of 9 nM.</p>Formule :C23H20ClF2N3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :411.87Syk Inhibitor II hydrochloride
CAS :<p>Syk signaling is key in lupus. Syk inhibitors reduce inflammation and sepsis severity in FcgRIIb-/- mice, lowering cytokines and organ damage.</p>Formule :C14H16ClF3N6ODegré de pureté :99.05%Couleur et forme :SolidMasse moléculaire :376.77p-HTAA
CAS :<p>Pentamer Hydrogen Thiophene Acetic Acid (p-HTAA) is a compound that specifically targets and labels amyloid-beta (Aβ) deposits in the brains of living mice [1].</p>Formule :C24H16O4S5Couleur et forme :SolidMasse moléculaire :528.71NMDA receptor antagonist 8
<p>Compound (R)-10a, an NMDA receptor antagonist, exhibits selectivity for the GluN2B subunit, possessing a Ki of 265 nM and an IC50 of 62 nM.</p>Formule :C22H27N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :349.47LY3027788
CAS :<p>LY3027788, potent oral prodrug of LY3020371, is a strong mGlu2/3 antagonist with notable antidepressant effects.</p>Formule :C25H31F2NO11SCouleur et forme :SolidMasse moléculaire :591.58NMDA receptor antagonist 7
<p>Compound (S)-10a, a GluN2B subunit-selective NMDA receptor antagonist, exhibits a K i of 93 nM and an IC 50 of 72 nM.</p>Formule :C22H27N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :349.47Orexin A (human, rat, mouse) (TFA)
<p>Endogenous orexin receptor agonist with Ki of 20 nM (OX1) and 38 nM (OX2), promotes feeding, may regulate sleep-wake cycle.</p>Formule :C154H244N47F3O46S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3675.12MAO-B-IN-20
<p>MAO-B-IN-20, potent with 0.037 μM IC50, is stable and BBB permeable, useful for Parkinson's research.</p>Formule :C20H18F2N2O2Couleur et forme :SolidMasse moléculaire :356.37Anti-inflammatory agent 53
<p>Anti-inflammatory agent 52 (compound 7c) is an orally active, selective COX-2 inhibitor with demonstrated anti-HT29 metastatic activity, causing periodic arrest</p>Formule :C24H22N2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.51COX-1/2-IN-4
<p>COX-1/2-IN-4 (compound 2b) is a dual COX-1 and COX-2 inhibitor with respective IC50 values of 0.239 μM for COX-1 and 0.191 μM for COX-2.</p>Formule :C22H24N2O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :380.5JPC0323
<p>JPC0323 is a dual positive allosteric modulator of the 5-HT2C and 5-HT2A receptors, featuring on-target properties, acceptable plasma exposure, and adequate</p>Formule :C22H43NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :385.58DOAM
CAS :<p>DOAM is an antagonist of the 5-HT2 receptor.</p>Formule :C16H27NO2Couleur et forme :SolidMasse moléculaire :265.39SPL-707
CAS :<p>SPL-707 is an effective and selective signal peptide peptidase-like 2a inhibitor (IC50: 80 nM).</p>Formule :C27H28FN5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :505.54PZ-1922
<p>PZ-1922 (Compound 16), able to cross the blood-brain barrier, is a dual antagonist for 5-HT6R and 5-HT3R with K i values of 17 nM and 0.45 nM, respectively.</p>Degré de pureté :98%Couleur et forme :Odour SolidSintamil
CAS :<p>Sintamil is a useful organic compound for research related to life sciences. The catalog number is T71697 and the CAS number is 16398-39-3.</p>Formule :C18H20ClN3O4Couleur et forme :SolidMasse moléculaire :377.82β-Amyloid (33-40)
CAS :<p>β-Amyloid (33-40) is a peptide comprising amino acids 33 to 40 of the beta-amyloid protein.</p>Formule :C32H58N8O9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :730.92CIA-1 (Free base)
CAS :<p>CIA-1, a COUP-TFII inhibitor, has IC50 of 1.2-7.6 μM in prostate cancer cells; inhibits tumor growth in mouse prostate cancer.</p>Formule :C17H19N3O2SDegré de pureté :99%Couleur et forme :SolidMasse moléculaire :329.42TIP 39, Tuberoinfundibular Neuropeptide
CAS :<p>TIP39 is a synthetic neuropeptide agonist for human and rat PTH2 receptors from the hypothalamus.</p>Formule :C202H325N61O54SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :4504.26,7-dimethylisatin
CAS :<p>6,7-Dimethylisatin (6,7-dimethyl-1H-indole-2,3-dione) inhibits hGAT3 with IC50 of 108 μM. 6,7-Dimethylisatin also inhibits hBGT1, hGAT2.</p>Formule :C10H9NO2Degré de pureté :98.98%Couleur et forme :SolidMasse moléculaire :175.18Ro 12-5637
CAS :<p>Ro 12-5637 is a metabolite of moclobemide.</p>Formule :C13H17ClN2O3Couleur et forme :SolidMasse moléculaire :284.745-HT2C agonist-4
CAS :<p>Compound 3i, a 5-HT2C agonist-4, acts as an agonist for the 5-HT2C receptor with an EC50 of 5.7 nM. It is capable of reducing locomotor activity in zebrafish larvae.</p>Formule :C24H25N5OCouleur et forme :SolidMasse moléculaire :399.49Emraclidine
CAS :<p>Emraclidine (CVL-231) is a novel, highly selective allosteric modulator of the muscarinic M4 receptor positive receptor.Cost-effective and quality-assured.</p>Formule :C20H21F3N4ODegré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :390.4β-Amyloid (11-22)
CAS :<p>β-Amyloid (11-22) is a peptide fragment of β-Amyloid.Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’s</p>Formule :C70H102N18O18Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1483.67M 8218
CAS :<p>M 8218 is a bioactive chemical.</p>Formule :C20H29NO2Couleur et forme :SolidMasse moléculaire :315.45LY-53857 free base
CAS :<p>LY-53857 free base is a bioactive chemical.</p>Formule :C23H32N2O3Couleur et forme :SolidMasse moléculaire :384.515β-Cholanic acid
CAS :<p>5β-Cholanic acid (5beta-Cholanic acid) is a potent γ-secretase modulator used in Alzheimer's disease research.</p>Formule :C24H40O2Degré de pureté :98.91% - 99.89%Couleur et forme :SoildMasse moléculaire :360.57NF023 hexasodium
CAS :<p>NF023 hexasodium is a selective and competitive P2X1 receptor antagonist, with IC50 values of 0.21 μM, 28.9 μM, > 50 μM and > 100 μM for human P2X1, P2X3, P2X2</p>Formule :C35H26N4Na6O21S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1168.92
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