Neuroscience
Les inhibiteurs en neurosciences sont des composés conçus pour moduler l'activité de protéines, d'enzymes ou de récepteurs spécifiques au sein du système nerveux. Ces inhibiteurs sont cruciaux pour étudier les mécanismes moléculaires sous-jacents au fonctionnement neuronal, à la transmission synaptique et aux maladies neurodégénératives. En ciblant les récepteurs des neurotransmetteurs, les canaux ioniques et les voies de signalisation, les inhibiteurs en neurosciences facilitent l'exploration du fonctionnement cérébral et le développement de stratégies thérapeutiques pour des troubles neurologiques tels que la maladie d'Alzheimer, de Parkinson et l'épilepsie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs en neurosciences de haute qualité pour soutenir vos recherches en neurobiologie, neuropharmacologie et sciences cognitives.
Sous-catégories appartenant à la catégorie "Neuroscience"
- récepteur 5-HT(1.025 produits)
- ACK(1 produits)
- AChR(647 produits)
- ATP Citrate Lyase(17 produits)
- Récepteur adrénergique(3.028 produits)
- BACE(37 produits)
- Bêta-amyloïde(231 produits)
- CaMK(73 produits)
- COX(602 produits)
- Récepteur de la dopamine(445 produits)
- Récepteur GABA(373 produits)
- Gamma-sécrétase(62 produits)
- GluR(265 produits)
- GlyT(26 produits)
- Récepteur de l'histamine(385 produits)
- LRRK2(42 produits)
- Récepteur de la mélatonine(26 produits)
- NMDAR(10 produits)
- Récepteur OX(41 produits)
- Récepteur opioïde(327 produits)
Affichez 12 plus de sous-catégories
5638 produits trouvés pour "Neuroscience"
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Renzapride
CAS :Renzapride (BRL 24924) is a mixed 5-hydroxytryptamine type 4 (5-HT4) agonist and 5-HT3 receptor antagonist used in the study of irritable bowel syndrome.Formule :C16H22ClN3O2Degré de pureté :98.97% - 99.09%Couleur et forme :SolidMasse moléculaire :323.82Ref: TM-T38507
1mg93,00€2mg124,00€5mg200,00€10mg359,00€25mg692,00€50mg945,00€100mg1.279,00€200mg1.701,00€Ketanserin tartrate
CAS :Ketanserin tartrate (KJK-945 tartrate) is a 5-HT2A receptor and α1-adrenergic receptor antagonist for the study of systemic sclerosis.Formule :C26H28FN3O9Degré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :545.51Pipecuronium bromide
CAS :Pipecuronium bromide (RGH-1106) is an nAChR antagonist that also acts as a non-depolarising steroidal neuromuscular blocker that causes muscle relaxation.Formule :C35H62Br2N4O4Degré de pureté :>99.99%Couleur et forme :PowderMasse moléculaire :762.7Rizatriptan
CAS :Rizatriptan (Risatriptan) is a selective 5-hydroxytryptamine 1B/1D receptor agonist used in the study of migraine.Formule :C15H19N5Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :269.35WAY-100635 maleate
CAS :WAY-100635 Maleate is a specific and effective 5-HT receptor antagonist (IC50=0.95 nM).Formule :C25H34N4O2·xC4H4O4Degré de pureté :99.96%Couleur et forme :White SolidMasse moléculaire :538.645Ref: TM-T3453
2mg43,00€5mg63,00€1mL*10mM (DMSO)74,00€10mg89,00€25mg150,00€50mg215,00€100mg316,00€500mg765,00€Xanomeline tartrate
CAS :Xanomeline tartrate (LY 246708 tartrate) 是 M1和 M4 mAChR 激动剂，具有抗精神病样活性，可改善认知，可用于研究精神分裂症和阿尔茨海默病。Formule :C18H29N3O7SDegré de pureté :99.19% - 99.99%Couleur et forme :SolidMasse moléculaire :431.5γ-Secretase modulator 13
CAS :γ-Secretase modulator 13 is a γ-secretase modulator (GSMs) that can be used to study Alzheimer's disease and tumors.Formule :C22H23FN6SDegré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :422.52EasyStep Human BNP(Brain Natriuretic Peptide) ELISA Kit
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human BNP, and the Human BNP standard plate wells that pre-coated using protein-related techniques are provided separately. Standard/Sample Diluent Buffer or samples are added to the appropriate microtiter plate wells ,then added a HRP-conjugated antibody specific to Human BNP. After TMB substrate solution is added, only those wells that contain Human BNP and HRP-conjugated antibody will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human BNP in the samples is then determined by comparing the OD of the samples to the standard curve.Couleur et forme :Colourless TransparentliquidJatrorrhizine chloride
CAS :Jatrorrhizine chloride (Neprotine chloride) is an alkaloid isolated from Rhizoma coptidis with neuroprotective, antimicrobial, and antiplasmodial activities.Formule :C20H20ClNO4Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :373.8Citalopram-d6
CAS :Produit contrôléApplications Labelled Citalopram (C505000), an inhibitor of serotonin (5-HT) uptake. Used as an antidepressant.
References Christensen, A.V., et al.: Eur. J. Pharmacol., 41, 153 (1977), Keller, M.B., et al.: J. Clin. Psychiatry, 61, 896 (2000), Von Moltke, L.L., et al.: Drug Metab. Dispos., 29, 1102 (2001),Formule :C202H6H15FN2OCouleur et forme :NeatMasse moléculaire :330.43Monepantel
CAS :Monepantel (AAD1566) is an organic anthelmintic and an antagonist of nAChRs from roundworms and esophageostomy.Formule :C20H13F6N3O2SDegré de pureté :99.83%Couleur et forme :White PowderMasse moléculaire :473.39Ref: TM-T16126
1mg93,00€5mg236,00€1mL*10mM (DMSO)259,00€10mg340,00€25mg670,00€50mg964,00€100mg1.378,00€S1RA
CAS :S1RA (E-52862)(E-52862) is a potent, selective antagonist of the sigma-1 receptor (σ1R, Ki=17 nM), demonstrating significant selectivity over the sigma-2Formule :C20H23N3O2Degré de pureté :99.45%Couleur et forme :SolidMasse moléculaire :337.42EasyStep Human EFNA1(Ephrin A1) ELISA Kit
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human EFNA1, and the Human EFNA1 standard plate wells that pre-coated using protein-related techniques are provided separately. Standard/Sample Diluent Buffer or samples are added to the appropriate microtiter plate wells ,then added a HRP-conjugated antibody specific to Human EFNA1. After TMB substrate solution is added, only those wells that contain Human EFNA1 and HRP-conjugated antibody will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human EFNA1 in the samples is then determined by comparing the OD of the samples to the standard curve.Couleur et forme :Colourless TransparentliquidSyk Inhibitor II
CAS :Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).Formule :C14H15F3N6ODegré de pureté :97.63%Couleur et forme :SolidMasse moléculaire :340.3Acephate-d3 (acetyl-d3)
CAS :Acephate-d3 (acetyl-d3) is a deuterated compound of Acephate. Acephate has a CAS number of 30560-19-1. Acephate is an anticholinesterase insecticide with a weak inhibitory effect on AChE in rats, but it can effectively inhibit AChE in cockroaches.Formule :C4H7D3NO3PSCouleur et forme :SolidMasse moléculaire :186.18Pyridostigmine-d6 bromide
CAS :Pyridostigmine D6 bromide is the deuterium labeled Pyridostigmine, which is a parasympathomimetic and a reversible inhibitor of cholinesterase.Formule :C9H13BrN2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :267.15Donepezil-d5
CAS :Donepezil-d5 is a deuterated compound of Donepezil. Donepezil has a CAS number of 120014-06-4. Donepezil is a piperidine-based, potent, specific, and reversible inhibitor of acetylcholinesterase (AChE). It can be used for the treatment of mild to moderate dementia of the Alzheimer's type.Formule :C24H24D5NO3Couleur et forme :SolidMasse moléculaire :384.52Sulindac EP Impurity C-d3
CAS :Sulindac EP Impurity C-d3 is a deuterated compound of Sulindac EP Impurity C. Sulindac EP Impurity C has a CAS number of 32004-67-4. (E/Z)-Sulindac sulfide is a potent γ-secretase modulator (GSM) that selectively reduces Aβ42 production in favor of shorter Aβ species. (E/Z)-Sulindac sulfide can be used for researching Alzheimer's disease [1].Formule :C20H14D3FO2SCouleur et forme :SolidMasse moléculaire :343.43Chlorpyrifos (diethyl-d10)
CAS :Chlorpyrifos (diethyl-d10) is a deuterated compound of Chlorpyrifos. Chlorpyrifos has a CAS number of 2921-88-2. Chlorpyrifos is an organothiophosphate cholinesterase inhibitor that is used as an insecticide and as an acaricide.Formule :C9H1D10Cl3NO3PSCouleur et forme :SolidMasse moléculaire :360.65Fenitrothion-d6 (O,O-dimethyl-d6)
CAS :Fenitrothion-d6 (O,O-dimethyl-d6) is a deuterated compound of Fenitrothion. Fenitrothion has a CAS number of 122-14-5. Fenitrothion is an organothiophosphate cholinesterase inhibitor. Fenitrothion is used as an insecticide.
Formule :C9H6D6NO5PSCouleur et forme :SolidMasse moléculaire :283.27R 59-022
CAS :R 59-022 (DKGI-I) is a DGK inhibitor and a 5-HT Receptor antagonist that blocks filovirus internalization in host cells.Formule :C27H26FN3OSDegré de pureté :98.55%Couleur et forme :SolidMasse moléculaire :459.58Ref: TM-T16709
1mg35,00€5mg74,00€1mL*10mM (DMSO)75,00€10mg119,00€25mg269,00€50mg447,00€100mg733,00€200mg973,00€Varenicline
CAS :Varenicline (CP 526555) is a selective partial agonist of the α4β2 nAChR and a full agonist of the α3β4 nAChR and α7 nAChR.Formule :C13H13N3Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :211.26Ref: TM-T4246L
2mg34,00€5mg50,00€1mL*10mM (DMSO)55,00€10mg75,00€25mg137,00€50mg200,00€100mg313,00€200mg464,00€Cyproheptadine hydrochloride
CAS :Cyproheptadine hydrochloride (Periactin hydrochloride) is a hydrochloride salt form of cyproheptadine which is a histamine receptor antagonist.Formule :C21H21N·HClDegré de pureté :99.88% - 99.97%Couleur et forme :SolidMasse moléculaire :323.86(+)-Tomoxetine hydrochloride
CAS :(+)-Tomoxetine hydrochloride is a bioactive chemical.Formule :C17H22ClNODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :291.82Tarextumab
CAS :Tarextumab is an anti-Notch2/3 mAb, a promising candidate for breast, lung, ovarian, and pancreatic cancers.Degré de pureté :95%Couleur et forme :LiquidMasse moléculaire :~150 kDaRocatinlimab
CAS :Rocatinlimab (AMG 451) (KHK4083) is a fully human, non-fucosylated IgG1 anti-OX40 monoclonal antibody indicated for atopic dermatitis (AD) research [1].Couleur et forme :LiquidRemternetug
CAS :Remternetug (LY3372993) is a humanised monoclonal antibody targeting N3pG-Aβ, recognising pyroglutamated Aβ within amyloid plaques, Alzheimer's disease.Degré de pureté :95% - 97.6% (SDS-PAGE); 98.7% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :144.87 kDaArazasetron HCl
CAS :Arazasetron is an antiemetic which acts as a 5-HT3 receptor antagonist, pKi = 9.27.Formule :C17H20ClN3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :349.81eeAChE/eqBuChE-IN-1
CAS :eeAChE/eqBuChE-IN-1 (compound 3F) serves as a reversible dual inhibitor of eeAChE/eqBuChE, exhibiting IC50 values of 1.3 μM and 0.81 μM, respectively. In addition, this compound demonstrates anti-inflammatory properties and provides neuroprotective effects against Aβ25-35-induced injury in PC12 cells [1].Formule :C14H16N2O2Couleur et forme :SolidMasse moléculaire :244.29Escitalopram
CAS :Escitalopram (Seroplex), a serotonin inhibitor for depression, curbs alcohol intake and is favored over tricyclics for tardive dyskinesia.Formule :C20H21FN2ODegré de pureté :99.82%Couleur et forme :White Or White Crystalline PowderMasse moléculaire :324.39BChE-IN-25
CAS :BChE-IN-25 (compound 4I) acts as a selective inhibitor of BChE, demonstrating an IC 50 of 3.77μM and exhibiting 22-fold greater selectivity towards BChE over AChE [1].Formule :C17H23NO2Couleur et forme :SolidMasse moléculaire :273.37Atropine hydrobromide
CAS :Atropine hydrobromide is a biochemical.Formule :C17H24BrNO3Couleur et forme :SolidMasse moléculaire :370.28Keto Ziprasidone
CAS :Ziprasidone, an antipsychotic agent, functions as a dual antagonist of 5-HT (serotonin) and dopamine receptors.Formule :C21H19ClN4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :426.92Anatabine dicitrate
Anatabine dicitrate is a tobacco alkaloid that can cross the blood-brain barrier.Formule :C22H28N2O14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :544.46Risperidone Mesylate
CAS :Risperidone Mesylate is a selective serotonin 5-HT2 receptor and dopamine D2 receptor blocker.Formule :C24H31FN4O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :506.59Unasnemab
CAS :Unasnemab (MT-3921) binds RGMa, promoting neuroregeneration and locomotor function, showing potential for spinal cord injury and regenerative research.Degré de pureté :95% - 97.4% (SDS-PAGE); 98.3% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :144.90 kDaBenmoxin
CAS :Benmoxin is a monoamine oxidase inhibitor (MAOI) that is irreversible and nonselective.Formule :C15H16N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :240.30Bapineuzumab
CAS :Bapineuzumab (AAB-001) is a humanised monoclonal antibody targeting amyloid-beta (Aβ), soluble and oligomeric forms of amyloid β, Alzheimer's disease (AD).Degré de pureté :95%Couleur et forme :LiquidMasse moléculaire :145.86 kDaDezamizumab
CAS :Dezamizumab is a humanized antibody targeting the serum amyloid P component (SAP) to clear amyloid fibrils via macrophage phagocytosis, for research in systemic amyloid diseases.Degré de pureté :95% - 98.2% (SDS-PAGE); 98.7% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :145.82 kDaDilpacimab
CAS :Dilpacimab (ABT165) is a dual-variable antibody that targets DLL4 and VEGF pathways, showing potential in cancer research by blocking angiogenesis and Notch.Degré de pureté :95% - 97.7% (SDS-PAGE); 95.6% (SEC-HPLC)Couleur et forme :LiquidN-Methyl amisulpride
CAS :N-Methyl amisulpride (Amisulpride impurity H) is a 5-HT7 receptor, D2 receptor, and D3 receptor antagonist used in the study of acute schizophrenia.Formule :C18H29N3O4SCouleur et forme :SolidMasse moléculaire :383.51AChE-IN-65
CAS :AChE-IN-65 (Compound DABA_1) serves as a mixed inhibitor of acetylcholinesterase (AChE), exhibiting a Ki of 556.4 μM against Electrophorus electricus AChE.Formule :C15H8N2O6Couleur et forme :SolidMasse moléculaire :312.23Monoamine Oxidase B inhibitor 4
CAS :Monoamine Oxidase B Inhibitor 4 (compound 1l), with a potent IC50 value of 8.3 nM, is a selective human monoamine oxidase-B (hMAO-B) inhibitor. This compound demonstrates anti-neuroinflammatory properties and exhibits low neurotoxicity. It effectively inhibits the release of NO, TNF-α, and IL-1β induced by LPS and Aβ1-42, and additionally mitigates the cytotoxic effects triggered by Aβ(1-42) .Formule :C15H11Cl2NO3Couleur et forme :SolidMasse moléculaire :324.16Ruthenium(II) Nitrosyl Chloride
CAS :Formule :RuCl3NODegré de pureté :>97.0%(T)Couleur et forme :Yellow to Amber to Dark red powder to crystalMasse moléculaire :255.45KB-R 7943
CAS :Formule :C16H17N3O3S·CH4O3SDegré de pureté :>98.0%(HPLC)Couleur et forme :White to Yellow to Green powder to crystalMasse moléculaire :427.49Prostaglandin F2α
CAS :Formule :C20H34O5Degré de pureté :>95.0%(T)Couleur et forme :White or Colorless to Almost white or Almost colorless powder to lump to clear liquidMasse moléculaire :354.49Tyrphostin AG 494
CAS :Formule :C16H12N2O3Degré de pureté :>98.0%(HPLC)(N)Couleur et forme :Light yellow to Amber to Dark green powder to crystalMasse moléculaire :280.284,5,6,7-Tetrabromobenzotriazole
CAS :Formule :C6HBr4N3Degré de pureté :>97.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :434.71Gestrinone
CAS :Formule :C21H24O2Degré de pureté :>98.0%(T)Couleur et forme :Light yellow to Yellow powder to crystalMasse moléculaire :308.42Hyodeoxycholic Acid
CAS :Formule :C24H40O4Degré de pureté :>98.0%(T)Couleur et forme :White to Orange to Green powder to crystalMasse moléculaire :392.58Serotonin Creatinine Sulfate Monohydrate
CAS :Formule :C14H19N5O2·H2SO4·H2ODegré de pureté :>98.0%(T)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :405.43Tomatine from Tomato
CAS :Formule :C50H83NO21Degré de pureté :>80.0%(HPLC)Couleur et forme :White to Yellow to Orange powder to crystalMasse moléculaire :1,034.20Medroxyprogesterone
CAS :Formule :C22H32O3Degré de pureté :>98.0%(HPLC)Couleur et forme :White to Almost white powder to crystalMasse moléculaire :344.50(-)-Deguelin
CAS :Formule :C23H22O6Degré de pureté :>95.0%(HPLC)Couleur et forme :White to Yellow to Green powder to crystalMasse moléculaire :394.42Pipamperone
CAS :Formule :C21H30FN3O2Degré de pureté :>98.0%(HPLC)Couleur et forme :White to Light yellow to Light orange powder to crystalMasse moléculaire :375.49Lubiprostone
CAS :Formule :C20H32F2O5Degré de pureté :>97.0%(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :390.47Tetrasodium 1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetate
CAS :Formule :C22H20N2Na4O10Degré de pureté :>98.0%(T)Couleur et forme :White to Almost white powder to crystalMasse moléculaire :564.371,2-Dimyristoyl-sn-glycero-3-phospho-rac-(1-glycerol) Sodium Salt
CAS :Formule :C34H66NaO10PDegré de pureté :>98.0%(T)Couleur et forme :White to Almost white powder to crystalMasse moléculaire :688.86Mirtazapine D3
CAS :Mirtazapine D3 is a deuterium labeled Mirtazapine. Mirtazapine is an inhibitor of 5-HT receptor .Formule :C17H19N3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :268.37Amitriptyline-d6 Hydrochloride
CAS :Amitriptyline-d6 Hydrochloride is a deuterated compound of Amitriptyline Hydrochloride. Amitriptyline Hydrochloride has a CAS number of 549-18-8. Amitriptyline Hydrochloride is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and antinociceptive activities.Formule :C20H18D6ClNCouleur et forme :SolidMasse moléculaire :319.90Homotaurine-d6
CAS :Homotaurine-d6 is a deuterated compound of Homotaurine. Homotaurine has a CAS number of 3687-18-1. Because of its similarity in structure to the neurotransmitter gamma-aminobutyric acid (GABA), it has GABAergic effects and may be useful as an anticonvulsant. Homotaurine has also been investigated as a potential treatment for Alzheimer's disease. It binds to soluble amyloid beta and inhibits the formation of neurotoxic aggregates that lead to amyloid plaque deposition in the brain. However, clinical trials failed to show improvement compared to placebo.Formule :C3D6H3NO3SCouleur et forme :SolidMasse moléculaire :145.21Milnacipran-d10 Hydrochloride
CAS :Milnacipran-d10 Hydrochloride is a deuterated compound of Milnacipran Hydrochloride. Milnacipran Hydrochloride has a CAS number of 101152-94-7. Levomilnacipran is a serotonin and norepinephrine reuptake inhibitor used to treat major depressive disorders. Levomilnacipran is an enantiomer of milnacipran, which is used to treat fibromyalgia. Levomilnacipran and milnacipran have been associated with a low rate of transient elevations in serum aminotransferase levels during treatment and with rare instances of clinically apparent acute liver injury with jaundice.Formule :C15H13D10ClN2OCouleur et forme :SolidMasse moléculaire :292.87Brexpiprazole-d8
CAS :Brexpiprazole D8 is a deuterium-modified partial agonist of 5-HT1A and dopamine receptors, with Ki values of 0.12 nM and 0.3 nM respectively.Formule :C25H27N3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :441.62AN317
CAS :AN317 is a selective agonist for the nicotinic acetylcholine receptor (nAChR) containing α6β2, with dissociation constants (Ki) of 6.2 nM and 4.1 nM for the α6/α3β2β3 and α4β2 receptor subtypes, respectively. It induces dopamine release in rat striatal synaptosomes, enhances the activity of dopaminergic neurons in the substantia nigra, and exhibits protective effects against the dopaminergic neurotoxin MPP+ in rat neurons. AN317 also demonstrates favorable pharmacokinetic properties in rats and permeability across the blood-brain barrier (BB).Formule :C13H19N3Couleur et forme :SolidMasse moléculaire :217.31Nicardipine pyridine metabolite II
CAS :Nicardipine pyridine metabolite II is a biaoctive chemical.Formule :C26H27N3O6Couleur et forme :SolidMasse moléculaire :477.51N-Biotinyl p-aminophenyl arsenic acid
CAS :N-Biotinyl p-aminophenyl arsenic acid is a bifunctional reagent that binds to streptavidin and disulfide compounds. It diminishes the binding sites of rbungarotoxin on reduced nicotinic receptors with an IC50 ranging from 10-300 nM, thus shielding the receptors from irreversible alkylation by bromoacetylcholine.Formule :C16H22AsN3O4SCouleur et forme :SolidMasse moléculaire :427.357-Acetoxy-1-methylquinolinium iodide
CAS :7-Acetoxy-1-methylquinolinium iodide (AMQI) is a cholinesterase substrate for inhibitor detection with 320 nm Ex and 410 nm Em.Formule :C12H12INO2Couleur et forme :SolidMasse moléculaire :329.13Penbutolol sulfate
CAS :Penbutolol sulfate ((-)-Terbuclomine) is able to bind to both β2-adrenergic receptor and β1-adrenergic receptor, thus making it a non-selective β blocker.Formule :C18H29NO2H2O4SDegré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :340.47Aβ1-42 aggregation inhibitor 1
CAS :Aβ1-42 aggregation inhibitor 1 effectively inhibits acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), demonstrating IC50 values of 2.64 μM and 1.29Formule :C29H32N4SCouleur et forme :SolidMasse moléculaire :468.66Aprofene
CAS :Aprofene blocks acetylcholine receptors, used for peptic ulcers, endarteritis, cholecystitis, and colitis.Formule :C21H27NO2Couleur et forme :SolidMasse moléculaire :325.44Pardoprunox
CAS :Pardoprunox (SLV-308) is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist properties.Formule :C12H15N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :233.27VU0477886
CAS :VU0477886: Potent mGlu4 PAM, effective in preclinical Parkinson's model HIC.Formule :C20H13ClN4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :392.80Eprodisate
CAS :Eprodisate disrupts protein-glycosaminoglycan binding, halting amyloid fibril formation, potentially delaying AA amyloidosis progression.Formule :C3H8O6S2Couleur et forme :SolidMasse moléculaire :204.22Aftin-5
CAS :Aftin-5 is an inducer of amyloid beta protein 42 (Aβ42). It functions by modifying the ultrastructure of mitochondria, leading to an upregulation of Aβ42 and a downregulation of Aβ38 through a β-secretase and γ-secretase-dependent mechanism. Aftin-5 exhibits mild cytotoxicity in SH-SY5Y, HT22, N2a, and N2a-AβPP695 cells, with IC50 values of 180, 194, 178, and 150 μM, respectively.Formule :C19H26N6OCouleur et forme :SolidMasse moléculaire :354.456-hydroxy Buspirone
CAS :6-Hydroxy Buspirone, an active metabolite of the anxiolytic compound buspirone, is produced via the cytochrome P450 (CYP) isoform CYP3A4.Formule :C21H31N5O3Couleur et forme :SolidMasse moléculaire :401.50Ketanserinol
CAS :Ketanserinol is a metabolite of the antihypertensive drug ketanserin, which blocks 5-HT2 receptors to treat protamine-induced pulmonary hypertension.Formule :C22H24FN3O3Couleur et forme :SolidMasse moléculaire :397.44SB 271046 hydrochloride
CAS :SB 271046 hydrochloride (SB 271046A) is selective, orally active 5-HT6 antagonist and is > 200-fold selective over 55 other receptors, enzymes and ion channels.Formule :C20H22ClN3O3S2·HClDegré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :488.455-Methyltryptamine hydrochloride
CAS :5-Methyltryptamine hydrochloride is a high-affinity 5-HT1C receptor ligand and a partial agonist of 5-HT. 5-Methyltryptamine hydrochloride protects mice subjected to burn, tourniquet and endotoxin shock.Formule :C11H15ClN2Degré de pureté :99.45%Couleur et forme :SolidMasse moléculaire :210.703Biperiden lactate
CAS :Biperiden lactate is a biochemical.Formule :C24H35NO4Couleur et forme :SolidMasse moléculaire :401.544-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine
CAS :4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine is a potent amyloid imaging agent that binds to Amyloid-β (1-40) (KD: 1.7 nM).Formule :C14H11BrN2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :319.22VU0029767
CAS :VU0029767 is an allosteric enhancer of the M1 muscarinic receptor, capable of modulating the receptor's activity. This compound enhances M1 receptor activity by increasing agonist affinity. However, VU0029767 demonstrates distinct characteristics from other compounds, particularly under varying experimental conditions such as its interaction with mutated M1 receptors and its effects on downstream signaling pathways.
Formule :C21H21N3O3Couleur et forme :SolidMasse moléculaire :363.41Catestatin
CAS :Non-competitive inhibitor of nicotinic receptors; blocks cationic signalling and catecholamine release; stimulates histamine release. IC50 ~200-250nM.Formule :C107H173N37O26SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2425.84Hydroxy ziprasidone
CAS :Hydroxy ziprasidone is an impurity of Ziprasidone. Ziprasidone, an antipsychotic agent, is a 5-HT and dopamine receptor antagonist.Formule :C21H21ClN4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :428.94Dianicline dihydrochloride
CAS :Dianicline dihydrochloride is a partial agonist of α4β2 nicotinic acetylcholine receptor. It increases cessation rates in a dose-dependent manner.Formule :C13H16N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :216.28Diclofensine
CAS :Diclofensine (Ro 8-4650) inhibits the uptake of serotonin, noradrenaline and dopamine.Formule :C17H17Cl2NODegré de pureté :97.01% - 98.13%Couleur et forme :SolidMasse moléculaire :322.237-Desmethyl-3-hydroxyagomelatine
CAS :7-Desmethyl-3-hydroxyagomelatine, less active than parent drug Agomelatine, is a melatonergic agonist and 5-HT2C antagonist.Formule :C14H15NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :245.27Phenglutarimide hydrochloride
CAS :Phenglutarimide hydrochloride is an anticholinergic. It is used as an antiparkinsonian agent.Formule :C17H25ClN2O2Couleur et forme :SolidMasse moléculaire :324.85MCI-225 dehydratase
CAS :MCI-225 dehydratase is an oral, selective inhibitor of noradrenaline reuptake, and functions as a 5-HT3 antagonist, exhibiting antidepressant effects in vivo .Formule :C17H18ClFN4SCouleur et forme :SolidMasse moléculaire :364.87(4-Hydroxy-3-methoxyphenyl)acetic-2,2-d2 Acid
CAS :Produit contrôléApplications (4-Hydroxy-3-methoxyphenyl)acetic-2,2-d2 Acid (CAS# 53587-33-0) is a useful isotopically labeled research compound.
Formule :C9H8D2O4Couleur et forme :NeatMasse moléculaire :184.192-(3-Chlorophenyl)-2-(methylamino)cyclohexanone Hydrochloride
CAS :Produit contrôléFormule :C13H17Cl2NOCouleur et forme :NeatMasse moléculaire :274.192Z-Nalfurafine
CAS :Produit contrôléApplications 2Z-Nalfurafine is a geometric isomer of Nalfurafine (N255600), a on-narcotic opioid drug for intractable itch caused by hemodialysis. It showed significant opioid κ-agonist activity and induced neither aversion nor preference in rats on the CPP (Conditioned Place Preference) test. Nalfurafine is a new therapeutic agent for the treatment of uremic pruritus in hemodialysis patients.
References Fujii, H., et al.: Bioorg. Med. Chem., 12, 4133 (2004); Mori, T., et al.: Life Sci., 75, 2433 (2004); Fujii, H., et al.: Curr. Med. Chem., 13, 1109 (2006); Nagase, H., et al.: Bioorg. Med. Chem. Lett., 20, 6302 (2010)Formule :C28H32N2O5Couleur et forme :NeatMasse moléculaire :476.566S-Nalfurafine
CAS :Produit contrôléApplications 6S-Nalfurafine is a stereoisomer of Nalfurafine (N255600), a on-narcotic opioid drug for intractable itch caused by hemodialysis. It showed significant opioid κ-agonist activity and induced neither aversion nor preference in rats on the CPP (Conditioned Place Preference) test. Nalfurafine is a new therapeutic agent for the treatment of uremic pruritus in hemodialysis patients.
References Fujii, H., et al.: Bioorg. Med. Chem., 12, 4133 (2004); Mori, T., et al.: Life Sci., 75, 2433 (2004); Fujii, H., et al.: Curr. Med. Chem., 13, 1109 (2006); Nagase, H., et al.: Bioorg. Med. Chem. Lett., 20, 6302 (2010)Formule :C28H32N2O5Couleur et forme :NeatMasse moléculaire :476.562-(4-Chlorophenyl)-2-(methylamino)cyclohexanone Hydrochloride
CAS :Produit contrôléFormule :C13H17Cl2NOCouleur et forme :NeatMasse moléculaire :274.19Dolasetron Mesylate
CAS :Dolasetron Mesylate (MDL-73147EF) is an antagonist of the 5-HT3 receptor and can be used in research on the treatment of vomiting and nausea followingFormule :C20H24N2O6SDegré de pureté :99.05%Couleur et forme :White PowderMasse moléculaire :420.48LY 344864
CAS :LY 344864, a specifc receptor agonist, is an affinity of 6 nM (Ki) at the recently cloned 5-HT1F receptor.Formule :C21H22FN3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :351.42Paroxetine hydrochloride hemihydrate
CAS :Paroxetine hydrochloride hemihydrate (Paxil) is an effective and selective serotonin reuptake inhibitor (SSRI).Formule :C38H44Cl2F2N2O7Degré de pureté :99.949%Couleur et forme :SolidMasse moléculaire :749.672-Methyl-5-HT maleate
CAS :2-Methyl-5-HT maleate, a selective 5-HT3 agonist, shows anti-depressive effects.Formule :C15H18N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :306.31FK-1052 HCl
CAS :FK-1052 HCl is a serotonin 3 & 4 dual receptor antagonist.Formule :C18H20ClN3OCouleur et forme :SolidMasse moléculaire :329.83Pralidoxime mesylate
CAS :Pralidoxime mesylate is a Cholinesterase ReactivatorFormule :C8H12N2O4SCouleur et forme :SolidMasse moléculaire :232.25Adinazolam Mesylate
CAS :Adinazolam Mesylate is an anxiolytic and antidepressant agent. Adinazolam Mesylate binds to peripheral-type benzodiazepine receptors that interact allosterically with GABA receptors as an agonist to produce inhibitory effects.Formule :C20H22ClN5O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :447.94
