Neuroscience
Les inhibiteurs en neurosciences sont des composés conçus pour moduler l'activité de protéines, d'enzymes ou de récepteurs spécifiques au sein du système nerveux. Ces inhibiteurs sont cruciaux pour étudier les mécanismes moléculaires sous-jacents au fonctionnement neuronal, à la transmission synaptique et aux maladies neurodégénératives. En ciblant les récepteurs des neurotransmetteurs, les canaux ioniques et les voies de signalisation, les inhibiteurs en neurosciences facilitent l'exploration du fonctionnement cérébral et le développement de stratégies thérapeutiques pour des troubles neurologiques tels que la maladie d'Alzheimer, de Parkinson et l'épilepsie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs en neurosciences de haute qualité pour soutenir vos recherches en neurobiologie, neuropharmacologie et sciences cognitives.
Sous-catégories appartenant à la catégorie "Neuroscience"
- récepteur 5-HT(939 produits)
- ACK(1 produits)
- AChR(575 produits)
- ATP Citrate Lyase(16 produits)
- Récepteur adrénergique(2.945 produits)
- BACE(36 produits)
- Bêta-amyloïde(205 produits)
- CaMK(69 produits)
- COX(561 produits)
- Récepteur de la dopamine(407 produits)
- Récepteur GABA(336 produits)
- Gamma-sécrétase(59 produits)
- GluR(255 produits)
- GlyT(24 produits)
- Récepteur de l'histamine(358 produits)
- LRRK2(33 produits)
- Récepteur de la mélatonine(24 produits)
- NMDAR(28 produits)
- Récepteur OX(40 produits)
- Récepteur opioïde(297 produits)
Affichez 12 plus de sous-catégories
5400 produits trouvés pour "Neuroscience"
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Frovatriptan
CAS :<p>Frovatriptan, potent 5-HT 1B/D agonist, shows high cerebroselectivity and efficacy for migraine with aura.</p>Formule :C14H17N3OCouleur et forme :SolidMasse moléculaire :243.35-HT2 agonist-1 free base
CAS :<p>Compound 24 (5-HT2 agonist-1 free base) is a potent agonist for 5-HT2A, 5-HT2B, and 5-HT2C receptors, exhibiting IC50 values of 10 nM, 8.3 nM, and 1.6 nM,</p>Formule :C19H22N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :310.39L-772,405
CAS :<p>L-772,405 is a highly selective agonists of h5-HT(1D) receptor.</p>Formule :C26H31FN6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :462.56MFZ 10-7
CAS :<p>MFZ 10-7 is anegative allosteric modulator of the mGluR5.</p>Formule :C15H9FN2Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :236.24Gentisein
CAS :<p>Gentisein (NSC-329491), a primary metabolite of Mangiferin, exhibits significant inhibition of serotonin uptake, demonstrating potency with an IC50 value of 4.7</p>Formule :C13H8O5Degré de pureté :96.89%Couleur et forme :SolidMasse moléculaire :244.2PTAC oxalate
CAS :<p>muscarinic receptor ligand</p>Formule :C14H21N3O4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :359.46SB 258719
CAS :<p>SB 258719 is a selective antagonist of 5-HT7 receptor with pKi of 7.5.</p>Formule :C18H30N2O2SDegré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :338.51BMS-932481
CAS :<p>BMS-932481 is a γ-secretase modulator.</p>Formule :C24H24FN7OCouleur et forme :SolidMasse moléculaire :445.49mGluR5 antagonist-1
CAS :<p>mGluR5 antagonist-1 (compound 10) is a potent mGluR5 inhibitor exhibiting an IC50 of 11.5 nM and demonstrates antidepressant effects [1].</p>Formule :C23H18N4O2Couleur et forme :SolidMasse moléculaire :382.41AMPA receptor modulator-5
CAS :<p>AMPA Receptor Modulator-5 (Example 217) serves as an AMPA receptor modulator, utilized in neurological disease research [1].</p>Formule :C20H12F4N6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :412.34NAS-181
CAS :<p>NAS-181 is a potent and selective rat 5-hydroxytryptamine 1B (r5-HT1B) antagonist (Ki: 47 nM).NAS-181 enhances the accumulation of 5-HTP in rat brain regions.</p>Formule :C20H30N2O7SCouleur et forme :SolidMasse moléculaire :442.53CGP 54626 hydrochloride
CAS :<p>CGP 54626 hydrochloride is a GABAB receptor antagonist.</p>Formule :C18H29Cl3NO3PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :444.76PZ-II-029
CAS :<p>PZ-II-029 is a modulator of α6β3γ2-selective GABAA channel.</p>Formule :C18H15N3O3Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :321.33(+)-Bicuculline methiodide
CAS :<p>(+)-Bicuculline methiodide is a GABAA receptor blocker that blocks epileptogens and may be used in the study of neurological disorders.</p>Formule :C21H20INO6Degré de pureté :99.24%Couleur et forme :SolidMasse moléculaire :509.29C3
CAS :<p>C3 functions as a selective inhibitor of monoamine oxidase B (MAO-B; IC50= 0.021 µM), demonstrating preference over monoamine oxidase A (MAO-A; IC50= 26.8 µM). This compound, at dosages of 0.1, 1, and 3 mg/kg, effectively counters MPTP-induced reductions in dopamine levels within the mouse brain.</p>Formule :C18H19FN2O2Couleur et forme :SolidMasse moléculaire :314.354-Chloro-L-phenylalanine
CAS :<p>4-Chloro-L-phenalanine (L-PCPA) is an inhibitor of 5-HT biosynthesis and a non-specific antagonist of tryptophan hydroxylases (TPH1 and TPH2).</p>Formule :C9H10ClNO2Degré de pureté :99.76% - 99.96%Couleur et forme :SolidMasse moléculaire :199.63Nemonapride
CAS :<p>Nemonapride is a dopamine D2-like receptor antagonist.</p>Formule :C21H26ClN3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :387.9CP-409092
CAS :<p>CP-409092 is a partial GABAA receptor agonist. It has anti-anxiety activity.</p>Formule :C17H19N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :297.35Indeloxazine hydrochloride
CAS :<p>Indeloxazine HCl: Serotonin releaser, NE reuptake inhibitor, NMDA antagonist; antidepressant that boosts acetylcholine in rats.</p>Formule :C14H18ClNO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :267.75P2X3-IN-1
CAS :<p>P2X3-IN-1 (example 7) is a P2X3 receptor inhibitor suitable for research on neurogenic diseases [1].</p>Formule :C22H21FN8O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :464.45ELND007
CAS :<p>ELND007 is a Gamma secretase inhibitor.</p>Formule :C19H14F4N4O2SCouleur et forme :SolidMasse moléculaire :438.4Anti-amyloid agent-1
CAS :<p>Anti-amyloid agent-1 is a potent compound that inhibits amyloid aggregation, offering a promising approach for research into the treatment of amyloidosis [1].</p>Formule :C21H17F3N2O3Couleur et forme :SolidMasse moléculaire :402.37Antioxidant agent-15
CAS :<p>Antioxidant agent-15 (Compound 4) demonstrates potent antioxidant inhibition activity, exhibiting an IC50 value of 15.44 nM.</p>Formule :C19H14O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :274.31UNC9994 hydrochloride
CAS :<p>UNC9994 hydrochloride is a selective β-arrestin-biased D2R agonist, Ki of 79 nM, that stimulates β-arrestin and modulates cAMP.</p>Formule :C21H23Cl3N2OSCouleur et forme :SolidMasse moléculaire :457.84P11149
CAS :<p>P11149: oral AChE inhibitor, crosses BBB, IC50 1.3 μM, based on Galanthamine, aims Alzheimer's research.</p>Formule :C27H34ClNO4Couleur et forme :SolidMasse moléculaire :472.02CGP-54626 free base
CAS :CGP-54626 is a selective antagonist of the GABAB receptor (IC50 = 4 nM ).Formule :C18H28Cl2NO3PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :408.3R-96544
CAS :<p>R-96544 is an orally active antagonist of the 5-HT2A receptor that has demonstrated the ability to inhibit platelet aggregation in vitro [1].</p>Formule :C22H30ClNO3Couleur et forme :SolidMasse moléculaire :391.93JM-1232
CAS :<p>JM-1232 is a sedative and hypnotic drug being researched as a potential anesthetic.</p>Formule :C24H27N3O2Couleur et forme :SolidMasse moléculaire :389.49NP-1815-PX
CAS :<p>NP-1815-PX is a P2X4R antagonist with anti-inflammatory and analgesic properties, inhibiting guinea pig tracheal, and can be used in chronic pain research.</p>Formule :C21H13N4NaO3SDegré de pureté :97.82% - 99.39%Couleur et forme :SolidMasse moléculaire :424.41Benoxaprofen
CAS :<p>Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.</p>Formule :C16H12ClNO3Degré de pureté :98.87%Couleur et forme :SolidMasse moléculaire :301.72(2R,4R)-APDC
CAS :<p>(2R,4R)-APDC is a selective group II metabotropic glutamate receptors (mGluRs) agonist. It has anticonvulsant and neuroprotective effects.</p>Formule :C6H10N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :174.15Abaperidone
CAS :<p>Abaperidone is an atypical antipsychotic, antagonizes 5-HT2A (IC50=6.2 nM) and D2 receptors (IC50=17 nM), reduces hsp70 mRNA in rat brains.</p>Formule :C25H25FN2O5Degré de pureté :98.22%Couleur et forme :SolidMasse moléculaire :452.47mGAT-IN-1
CAS :<p>mGAT-IN-1 is a potent, non-selective GAT inhibitor that inhibits mGAT3 activity well (IC50: 2.5 μM, pIC50: 5.61).</p>Formule :C28H34ClN3O2S2Couleur et forme :SolidMasse moléculaire :544.17BACE1-IN-10
CAS :<p>BACE1-IN-10 is a potent inhibitor of BACE1, demonstrating sub-micromolar activity against recombinant BACE1 (rBACE1) [1].</p>Formule :C33H49N5O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :675.846,2'-Dihydroxyflavone
CAS :<p>6,2'-Dihydroxyflavone is a novel antagonist of GABAA receptor.</p>Formule :C15H10O4Degré de pureté :99.44% - 99.67%Couleur et forme :SolidMasse moléculaire :254.24mAChR antagonist 1
CAS :<p>Compound 4a, a mAChR antagonist, exhibits K i values of 255 nM for M1 and M5 subtypes, and lower values of 121 nM and 158 nM for M3 and M4 subtypes,</p>Formule :C19H22N2O2Couleur et forme :SolidMasse moléculaire :310.39VU6012962
CAS :<p>VU6012962 is an orally bioavailable negative allosteric modulator of CNS-penetrant metabotropic glutamate receptor 7(mGlu7; IC50: 347 nM).</p>Formule :C21H19F3N4O4Degré de pureté :99.61% - 99.74%Couleur et forme :SolidMasse moléculaire :448.45-HT2C agonist-3
CAS :<p>5-HT2C agonist-3 ((+)-19), a selective 5-HT2C agonist (EC 50: 24 nM, Ki: 78 nM), exhibits antipsychotic-like activity by blocking amphetamine-induced</p>Formule :C19H23ClFNO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :351.84MAO-B-IN-19
CAS :<p>MAO-B-IN-19, a selective MAO-B inhibitor, exhibits neuroprotective and anti-inflammatory properties and demonstrates an IC50 value of 0.67 μM [1].</p>Formule :C15H11FO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :242.25Afizagabar
CAS :<p>Afizagabar, a first-in-class α5-GABAAR antagonist, IC50: 585 nM, Ki: 66 nM, may boost memory.</p>Formule :C19H12FN3O2SCouleur et forme :SolidMasse moléculaire :365.38LY2033298
CAS :<p>LY2033298 enhances oximoline's effect on hamster circadian rhythms, aiding neurosystem disorders.</p>Formule :C13H14ClN3O2SDegré de pureté :99.06%Couleur et forme :SolidMasse moléculaire :311.79P2X3 antagonist 38
CAS :<p>Compound 38, also known as Compound 4, is a potent, orally active P2X3 antagonist that demonstrates inhibitory activity with IC50 values of 0.132 µM, 0.165 µM,</p>Formule :C22H25F3N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :478.47CGP36216 hydrochloride
CAS :<p>CGP36216 hydrochloride acts as a selective antagonist at the presynaptic GABA receptor, specifically binding to the GABAB receptor with a Ki value of 0.3 μM. This compound is leveraged in research focused on anxiety and trauma-related disorders [1] [2].</p>Formule :C5H15ClNO2PCouleur et forme :SolidMasse moléculaire :187.6BACE-1 inhibitor 1
CAS :<p>BACE-1 inhibitor 1 (Compound 8a) is an effective BACE-1 inhibitor (IC50: 56 nM).</p>Formule :C17H14BrF3N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :443.225-HT2A receptor agonist-3
CAS :<p>5-HT2A receptor agonist-3 represents the highest selectivity for the human 5-HT2A receptor currently identified, exhibiting a K i of 2.5 nM.</p>Formule :C21H26BrNO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :420.34L 663581
CAS :<p>L 663581 is the benzodiazepine receptor partial agonist.</p>Formule :C17H16ClN5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :357.79AChE-IN-44
CAS :<p>AChE-IN-44 (Compound Tap4), an AChE inhibitor, is convertible into its thiazole salt form known as Tat2 [1].</p>Formule :C31H38ClN3OS2Couleur et forme :SolidMasse moléculaire :568.24Timepidium bromide
CAS :<p>Timepidium bromide is an agent of anticholinergic.</p>Formule :C17H22BrNOS2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :400.4Calmidazolium chloride
CAS :<p>Calmidazolium chloride blocks calmodulin, hinders phosphodiesterase (IC50=0.15µM), Ca2+-ATPase (IC50=0.35µM), and can induce cancer cell apoptosis.</p>Formule :C31H23Cl7N2ODegré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :687.7VU0453595
CAS :<p>VU0453595 is a M1 positive allosteric modulator (PAM).</p>Formule :C18H15FN4ODegré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :322.34(-)-Bicuculline methochloride
CAS :<p>(-)-Bicuculline methochloride is a potent antagonist of GABAA receptor.</p>Formule :C21H20ClNO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :417.84L-AP4
CAS :<p>L-APB is an effective and specific agonist for the group III mGluRs (EC50s: 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6, and mGlu7 receptors, respectively).</p>Formule :C4H10NO5PDegré de pureté :98%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :183.1Muscarine tosylate
CAS :<p>Muscarine ((+)-Muscarine) tosylate, a prototype mAChR agonist, serves as a parasympathetic nervous system stimulant and is recognized for its toxic properties [1] [2].</p>Formule :C16H27NO5SCouleur et forme :SolidMasse moléculaire :345.45BChE-IN-20
CAS :<p>BChE-IN-20 (compound 7c) is a potent, selective inhibitor of BChE, demonstrating IC50 values of 105 nM for eqBChE and 2.3 nM for hBChE.</p>Formule :C27H39N5O2Couleur et forme :SolidMasse moléculaire :465.63SCS
CAS :<p>SCS is a GABAA receptor antagonist.</p>Formule :C14H12N2O3Degré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :256.26BACE1-IN-13
CAS :<p>BACE1-IN-13 (Compound 36), an orally active inhibitor of BACE1, exhibits high potency with an IC50 of 2.9 nM and demonstrates greater efficacy in hAβ42 cells (</p>Formule :C20H17FN8O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :420.45-HT3 antagonist 1
CAS :<p>5-HT3 antagonist 1 is a potent and selective antagonist of 5-HT3 receptor.</p>Formule :C22H27N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :377.485-HT2 agonist-1
CAS :<p>Compound 24, a 5-HT2 agonist-1, selectively activates 5-HT2A, 5-HT2B, and 5-HT2C receptors with IC50 values of 10 nM, 8.3 nM, and 1.6 nM, respectively.</p>Formule :C19H23ClN2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :346.85QR-0217
CAS :<p>QR-0217 is a potent inhibitor of both Aβ1-40 and α-synuclein aggregation, exhibiting an IC50 of 7.5 µM for Aβ1-40.</p>Formule :C19H13NO3Couleur et forme :SolidMasse moléculaire :303.31Brasofensine
CAS :<p>Brasofensine, a benztoalkane MA reuptake inhibitor, shows promise for Parkinson's and Alzheimer's.</p>Formule :C16H20Cl2N2OCouleur et forme :SolidMasse moléculaire :327.25Befiradol
CAS :<p>Befiradol (NLX-112) is an agonist of 5-HT1A receptor.</p>Formule :C20H22ClF2N3OCouleur et forme :SolidMasse moléculaire :393.86LY108742
CAS :<p>LY108742 is an antagonist of 5-HT2.</p>Formule :C21H28N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :356.46MK-8768
CAS :<p>MK-8768 is a potent, selective, and orally bioavailable negative allosteric modulator of the mGluR2 class, exhibiting an IC50 of 9.6 nM and characterized by</p>Formule :C21H22F3N5O2Couleur et forme :SolidMasse moléculaire :433.43Aβ/tau aggregation-IN-3
CAS :<p>Aβ/tau aggregation-IN-3 is a potent inhibitor of amyloid protein aggregation, exhibiting an IC50 value of 0.85 µM in an Aβ-Thioflavin T (Aβ-ThT) functional</p>Formule :C23H22N4O3Couleur et forme :SolidMasse moléculaire :402.455-HT2C agonist-3 free base
CAS :<p>5-HT2C agonist-3 ((+)-19) free base, a selective 5-HT2C agonist (EC50: 24 nM, Ki: 78 nM), exhibits antipsychotic drug-like activity and inhibits Amphetamine-</p>Formule :C19H22FNO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :315.38TPA 023
CAS :<p>TPA 023 is a selective agonist of GABAA α2/α3 subtype (Kis = 0.19 - 0.41 nM).</p>Formule :C20H22FN7ODegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :395.43COR659
CAS :<p>COR659: suppresses alcohol/chocolate intake in rats; enhances GABAB receptor, blocks CB1 receptor.</p>Formule :C16H16ClNO3SDegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :337.82rel-HDMP 28 hydrochloride
CAS :<p>Rel-HDMP-28 hydrochloride (Compound 2g) is an analogue of methylphenidate, exhibiting selective affinity for the serotonin transporter (SERT) with a binding constant (Ki) of 105 nM [1].</p>Formule :C18H22ClNO2Couleur et forme :SolidMasse moléculaire :319.83VU0029251
CAS :<p>VU0029251 serves as a partial antagonist of mGluR5, exhibiting a binding affinity with a K i of 1.07 μM.</p>Formule :C10H11N3S2Couleur et forme :SolidMasse moléculaire :237.34AAK1-IN-3
CAS :<p>AAK1-IN-3: Brain-penetrant AAK1 inhibitor for neuropathic pain research; IC50=11 nM.</p>Formule :C20H20N4Couleur et forme :SolidMasse moléculaire :316.4Dothiepin
CAS :<p>Dothiepin (Dosulepin; Dothep), an antidepressant with sedative/anxiolytic properties, preferentially inhibits noradrenaline over serotonin uptake, enhancing</p>Formule :C19H21NSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :295.44AChE-IN-31
CAS :<p>AChE-IN-31 (compound 1), a non-competitive acetylcholinesterase (AChE) inhibitor, exhibits potential for Alzheimer's disease research [1].</p>Formule :C27H44Na2O9S2Couleur et forme :SolidMasse moléculaire :622.74MGS-0039
CAS :<p>MGS-0039: Group II mGluR2/3 antagonist, non-serotonergic antidepressant-like effect, AMPA involvement, regulates dopamine in NAc.</p>Formule :C15H14Cl2FNO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :378.18ABT-418 hydrochloride
CAS :<p>ABT-418 HCl enhances cognition and reduces anxiety as a selective nAChRs agonist, researched for Alzheimer's.</p>Formule :C9H15ClN2OCouleur et forme :SolidMasse moléculaire :202.685-HT3-In-1
CAS :<p>5-HT3-In-1 (compound example 8) exhabits with 5-HT3 inhibition activity.</p>Formule :C16H21ClN4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :352.82AAK1-IN-4
CAS :<p>AAK1-IN-4 selectively inhibits AAK1 with IC50 of 4.6 nM; penetrates CNS, oral bioactive, potential for studying neuropathic pain.</p>Formule :C20H28N4O3Couleur et forme :SolidMasse moléculaire :372.46mGAT3/4-IN-2
CAS :<p>mGAT3/4-IN-2 are potent inhibitors of mGAT3/mGAT4 with their pIC50 values of 5.44 and 5.25, respectively.</p>Formule :C26H32ClN3OS2Couleur et forme :SolidMasse moléculaire :502.13AAK1-IN-5
CAS :<p>AAK1-IN-5: Potent, selective AAK1 inhibitor; CNS-penetrant; oral; IC50: 1.2 nM; Ki: 0.05 nM; cell IC50: 0.5 nM. Useful in neuropathic pain research.</p>Formule :C19H23F4N3OCouleur et forme :SolidMasse moléculaire :385.4Quinolactacin A1
CAS :<p>Quinolactacin A1, a strong AChE inhibitor from Penicillium citrinum, aids Alzheimer's research.</p>Formule :C16H18N2O2Couleur et forme :SolidMasse moléculaire :270.33QM-FN-SO3
CAS :<p>QM-FN-SO3 is a blood-brain barrier (BBB)-penetrable, near-infrared (NIR) probe with aggregation-induced emission (AIE) activity, specifically designed for the detection of Aβ plaques. It exhibits ultra-high signal-to-noise (S/N) ratio, binding affinity, and high-performance NIR emission, making it suitable for in vivo detection of Aβ plaques [1].</p>Formule :C29H25N4NaO3S2Couleur et forme :SolidMasse moléculaire :564.65Brasofensine sulfate
CAS :<p>Brasofensine sulfate is a dopamine reuptake inhibitor.</p>Formule :C16H22Cl2N2O5SCouleur et forme :SolidMasse moléculaire :425.33Bisnorcymserine
CAS :<p>Bisnorcymserine reversibly inhibits butyrylcholinesterase, binding Ser(200) and His(440) non-covalently and stacking with Trp(84).</p>Formule :C21H25N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :351.44VU 0255035
CAS :<p>VU 0255035 is a highly selective, competitive and brain penetrant muscarinic M1 receptor antagonist with an IC50 of 130 nM.</p>Formule :C18H20N6O3S2Degré de pureté :98.09% - 98.1%Couleur et forme :SolidMasse moléculaire :432.52MAO-B-IN-13
CAS :<p>MAO-B-IN-13: a potent, reversible MAO-B inhibitor with BBB penetration, neuroprotective effects; used in Parkinson’s research (IC50=10nM).</p>Formule :C18H19NO3Couleur et forme :SolidMasse moléculaire :297.35Gepirone
CAS :<p>Gepirone is a 5-HT1A receptor agonist belonging to the buspirone family. Gepirone HCl possesses greater selectivity for the 5-HT1A receptor than SSRIs.</p>Formule :C19H29N5O2Degré de pureté :99.35% - 99.89%Couleur et forme :SolidMasse moléculaire :359.47Zamifenacin fumarate
CAS :<p>Zamifenacin fumarate (UK-76654 fumarate) is a potent and gut-selective antagonist of muscarinic M3 receptor.</p>Formule :C31H33NO7Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :531.6L-822179
CAS :<p>L-822179 (α5IA) is a selective inverse agonist for the Α5 subtype of GABAA receptor with higher intrinsic activity at the A5 subtype than other drugs.</p>Formule :C17H14N8O2Degré de pureté :98.5% - 99.61%Couleur et forme :SolidMasse moléculaire :362.35MTPG
CAS :<p>Group II/group III metabotropic glutamate receptor antagonist</p>Formule :C10H11N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :233.23BMS 433796
CAS :<p>BMS 433796 is a γ-secretase inhibitor that demonstrates Aβ-lowering activity within a transgenic mouse model of Alzheimer's disease.</p>Formule :C21H20F2N4O4Degré de pureté :99.17%Couleur et forme :SolidMasse moléculaire :430.4AChE-IN-30
CAS :<p>AChE-IN-30 is an acetylcholinesterase (AChE) inhibitor exhibiting neuroprotective effects with an inhibitory concentration (IC 50) of 4.4 μM.</p>Formule :C22H24N4O2Couleur et forme :SolidMasse moléculaire :376.45AAK1-IN-2
CAS :<p>AAK1-IN-2, a potent (IC50=5.8 nM) AAK1 inhibitor, selective & brain-penetrant, is used for neuropathic pain studies.</p>Formule :C20H20N4Couleur et forme :SolidMasse moléculaire :316.4Tiotropium Bromide hydrate
CAS :<p>Tiotropium Bromide hydrate is a potent, long-lasting anticholinergic bronchodilator for COPD, with high affinity for muscarinic receptors M1, M2, and M3.</p>Formule :C19H24BrNO5S2Degré de pureté :98.44% - 99.41%Couleur et forme :SolidMasse moléculaire :490.433β-Hydroxy-lup-20(29)-en-16-one
CAS :<p>3β-Hydroxy-lup-20(29)-en-16-one (compound 9) serves as a dual inhibitor of both AChE and BChE, displaying a preference for BChE with an IC50 of 28.9 μM [1].</p>Formule :C30H48O2Couleur et forme :SolidMasse moléculaire :440.7Pomaglumetad methionil hydrochloride
CAS :<p>LY2140023 hydrochloride: oral methionine prodrug of LY404039, a selective mGlu2/3 agonist, studied for schizophrenia.</p>Formule :C12H19ClN2O7S2Degré de pureté :98.57%Couleur et forme :SolidMasse moléculaire :402.87Diproqualone
CAS :<p>Diproqualone, analogous to methaqualone, exhibits sedative, anxiolytic, anti-inflammatory, and analgesic properties [1].</p>Formule :C12H14N2O3Couleur et forme :SolidMasse moléculaire :234.255BMT-124110
CAS :<p>BMT-124110: AAK1 inhibitor, IC50=0.9 nM, pain relief. BMT-090605: BIKE inhibitor, IC50=17 nM; GAK inhibitor, IC50=99 nM.</p>Formule :C21H27N3O3Degré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :369.46Brilaroxazine
CAS :<p>Brilaroxazine (RP5063): multimodal dopamine/5-HT modulator, partial agonist at D2/D3/D4, 5-HT1A/2A, and antagonist at 5-HT2B/7.</p>Formule :C22H25Cl2N3O3Degré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :450.36CAY10649
CAS :<p>1CAY10649, a thiazolinone compound, directly inhibits 5-lipoxygenase (5-LO) product formation in intact polymorphonuclear leukocytes (PMNL) with an IC50 value of 0.28 μM and in a soluble fraction of an S100 PMNL cell lysate with an IC50 value of 0.09 μM, following stimulation by calcium and arachidonic acid. This activity highlights its potential in mitigating inflammatory responses by targeting the biosynthesis of leukotrienes, substances implicated in various inflammatory processes such as neutrophil chemotaxis, increased vascular permeability, and smooth muscle contraction.</p>Formule :C17H12ClNO2SCouleur et forme :SolidMasse moléculaire :329.8UNC9994
CAS :<p>UNC9994 is a β-arrestin-biased dopamine D₂ receptor agonist (β-arrestin EC50 = 50 nM; Emax = 97%) with robust in vivo antipsychotic drug-like activities.</p>Formule :C21H22Cl2N2OSCouleur et forme :SolidMasse moléculaire :421.38Piperidine-4-sulfonic acid
CAS :<p>Piperidine-4-sulfonic acid is a potent GABA agonist, demonstrating an IC50 value of 0.034 μM for the inhibition of H-GABA binding [1].</p>Formule :C5H11NO3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :165.21
