récepteur 5-HT
Les récepteurs 5-HT, également connus sous le nom de récepteurs de la sérotonine, sont un groupe de récepteurs couplés aux protéines G (GPCR) qui médiatisent les effets de la sérotonine, un neurotransmetteur impliqué dans la régulation de l'humeur, l'anxiété, le sommeil, l'appétit et d'autres processus physiologiques. Ces récepteurs sont divisés en plusieurs sous-types, chacun ayant des fonctions et des propriétés pharmacologiques distinctes. Les modulateurs des récepteurs 5-HT sont largement étudiés pour leurs rôles dans le traitement de la dépression, des troubles anxieux et d'autres affections neuropsychiatriques. Chez CymitQuimica, nous offrons une gamme de modulateurs des récepteurs 5-HT de haute qualité pour soutenir vos recherches en neuropharmacologie, troubles de l'humeur et signalisation GPCR.
940 produits trouvés pour "récepteur 5-HT"
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5-HT1AR/5-HT6R ligand-1
<p>5-HT1AR/5-HT6R ligand-1 (Compound PP13) functions as a ligand for the 5-HT receptor, demonstrating high affinity for 5-HT1AR, 5-HT6R, and 5-HT7R with Ki values of 19, 69, and 198 nM, respectively. In HEK293 cells, it inhibits cAMP production with EC50 values of 1535, 488, and 53 nM for these receptors. Additionally, 5-HT1AR/5-HT6R ligand-1 exhibits antiproliferative effects on several cancer cell lines, including 1321N1, U87MG, MCF7, and AsPC-1, with IC50 values of 9.6, 13.6, 19.3, and 14.6 μM, respectively. The compound also shows antagonistic activity towards the dopamine receptor D2R, with a Ki of 1903 nM.</p>Formule :C25H29ClN4O2SCouleur et forme :SolidMasse moléculaire :485.04SB656104
CAS :<p>SB656104 is a bioactive chemical.</p>Formule :C25H30ClN3O3SCouleur et forme :SolidMasse moléculaire :488.04Dehydro Aripiprazole (hydrochloride)
CAS :<p>Dehydro aripiprazole, an active atypical antipsychotic metabolite of aripiprazole, is formed by CYP3A4 and CYP2D6.</p>Formule :C23H26Cl3N3O2Couleur et forme :SolidMasse moléculaire :482.83Tryptamine hydrochloride
CAS :<p>Tryptamine hydrochloride is a monoamine alkaloid, metabolite of tryptophan and CNS active substance, agonist of 5-HT4 receptor, TAAR1, AHR.</p>Formule :C10H13ClN2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :196.68Mosapride citrate dihydrate
CAS :<p>Mosapride Citrate, a 5-HT4 agonist, boosts gut movement by enhancing acetylcholine release.</p>Formule :C27H35ClFN3O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :632.04LE 300
CAS :<p>LE 300 represents a structurally novel type of antagonists acting preferentially at the dopamine D(1)/D(5)receptors and the serotonin 5-HT(2A)receptor.</p>Formule :C20H22N2Degré de pureté :97.91% - 98.79%Couleur et forme :SolidMasse moléculaire :290.4(Iso)-Landipirdine
CAS :<p>(Iso)-Landipirdine((Iso)-RO5025181) is a selective and potent 5-HT6R antagonist.</p>Formule :C18H19FN2O3SDegré de pureté :98.50%Couleur et forme :SoildMasse moléculaire :362.42Mirtazapine N-oxide
CAS :<p>Mirtazapine N-oxide, a mirtazapine metabolite, is produced by CYP1A2 and CYP3A4 in human liver.</p>Formule :C17H19N3OCouleur et forme :SolidMasse moléculaire :281.359Xylamidine
CAS :<p>Xylamidine is a biochemical.</p>Formule :C19H24N2O2Couleur et forme :SolidMasse moléculaire :312.41isomer-Cilansetron
CAS :<p>isomer-Cilansetron is an isomer of Cilansetron.</p>Formule :C20H21N3ODegré de pureté :99.92% - 99.96%Couleur et forme :SoildMasse moléculaire :319.45-methoxy-α-Ethyltryptamine
CAS :<p>5-Methoxy-alpha-ethyltryptamine is a psychoactive substance that can cause various effects. It belongs to the tryptamine chemical class and can be used for various psychoactive and stimulant effects. </p>Formule :C13H18N2ODegré de pureté :98.25%Couleur et forme :SolidMasse moléculaire :218.29Xaliproden
CAS :<p>Xaliproden is a biochemical.</p>Formule :C24H22F3NCouleur et forme :SolidMasse moléculaire :381.43LY-53857 free base
CAS :<p>LY-53857 free base is a bioactive chemical.</p>Formule :C23H32N2O3Couleur et forme :SolidMasse moléculaire :384.51Fabesetron
CAS :<p>Fabesetron (FK1052): oral dual antagonist for 5-HT3/5-HT4 receptors. Aids in managing acute and delayed chemo-induced emesis.</p>Formule :C18H19N3OCouleur et forme :SolidMasse moléculaire :293.37Cannabidiolic acid methyl ester
CAS :<p>Cannabidiolic acid methyl ester (HU-580) is an orally active analogue of cannabidiolic acid. It enhances the activation of 5-HT1A receptors and increases the expression of c-Fos and NeuN in specific hypothalamic nuclei in rats. Cannabidiolic acid methyl ester exhibits anti-nausea, anxiolytic, and anti-nociceptive effects.</p>Formule :C23H32O4Couleur et forme :SolidMasse moléculaire :372.5Quetiapine-d4 fumarate
CAS :<p>Deuterium-labeled Quetiapine fumarate; an antidepressant and anxiolytic 5-HT agonist, dopamine antagonist.</p>Formule :C25H29N3O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :503.61Desmethyl Mirtazapine (hydrochloride)
CAS :<p>Desmethyl mirtazapine is a metabolite of the antidepressant mirtazapine.1It is formed from mirtazapine by the cytochrome P450 (CYP) isoform CYP3A4.</p>Formule :C16H18ClN3Couleur et forme :SolidMasse moléculaire :287.79SB 699551
CAS :<p>SB 699551 is a selective 5-HT5A antagonist (Ki=6.31 nM) that enhances 5-HT neuronal function. It inhibits SERT (Ki=25.12 nM),inhibit breast cancer.</p>Formule :C34H45N3ODegré de pureté :99.83%Masse moléculaire :511.74Nemifitide diTFA
CAS :<p>Nemifitide diTFA is a synthetic pentapeptide with antidepressant properties, resembling MIF, that crosses the blood-brain barrier.</p>Formule :C37H45F7N10O10Degré de pureté :99.78% - 99.84%Couleur et forme :SolidMasse moléculaire :922.8LEK 8804
CAS :<p>LEK 8804 is a 5-HT(2) receptor antagonist and 5-HT(1A) receptor agonist.</p>Formule :C19H19N3OCouleur et forme :SolidMasse moléculaire :305.37Triazolomethylindole-3-acetic acid
CAS :<p>Triazolomethylindole-3-acetic acid is a metabolite of Rizatriptan, which acts as an agonist for the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D.</p>Formule :C13H12N4O2Couleur et forme :SolidMasse moléculaire :256.26Isobutyryl-L-carnitine
CAS :<p>Isobutyryl-L-carnitine is a member of the class of compounds known as acylcarnitines. Isobutyryl-L-carnitine is a product of the acyl-CoA dehydrogenases.</p>Formule :C11H21NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :231.29MR33317
<p>MR33317 is an inhibitor of acetylcholinesterase with an IC50 value of 41 nM. Additionally, it acts as an agonist for brain 5-HT4 receptors.</p>Formule :C22H28ClN3O2Masse moléculaire :401.187(R,R)-Palonosetron Hydrochloride
CAS :<p>(R,R)-Palonosetron Hydrochloride is the active enantiomer of Palonosetron</p>Formule :C19H25ClN2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :332.87R 50595
CAS :<p>R 50595 is a selective non-competitive cisapride antagonist.</p>Formule :C30H35Cl2F2N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :594.52Cinanserin hydrochloride
CAS :<p>Cinanserin hydrochloride (SQ 10643) is a 5-HT2 receptor blocker (Ki: 41 nM) and SARS-CoV 3C-like protease inhibitor.</p>Formule :C20H25ClN2OSDegré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :376.94Zalospirone
CAS :<p>Zalospirone is a 5-HT1A receptor agonist that can be used to study anxiety disorders and major depressive disorder.</p>Formule :C24H29N5O2Degré de pureté :98.41% - 99.82%Couleur et forme :SolidMasse moléculaire :419.52DSP-1053
CAS :<p>Dsp-1053 is a powerful SERT (Ki=1.02 nM) inhibitor with partial 5-HT1A receptor (Ki=5.05 nM) agonizing activity.</p>Formule :C26H32BrNO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :502.44Peptide 401
CAS :<p>Peptide 401: AMP from bee/wasp venom, triggers histamine release, reduces paw swelling.</p>Formule :C110H192N40O24S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2587.22Alverine hydrochloride
CAS :<p>Alverine hydrochloride is a parasympatholytic.</p>Formule :C20H28ClNCouleur et forme :SolidMasse moléculaire :317.9Vortioxetine D8
CAS :<p>Vortioxetine D8 is a deuterium-labeled antidepressant inhibiting 5-HT1A/B, 5-HT3A, 5-HT7 receptors & SERT (Ki: 15-1.6 nM).</p>Formule :C18H22N2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :306.51,8-Cineole
CAS :<p>Eucalyptol, a natural monoterpenoid and cyclic ether found in eucalyptus species, effectively controls excessive airway mucus secretion and asthma by inhibiting pro-inflammatory cytokines. It serves as an efficacious treatment for non-purulent sinusitis, reducing inflammation and pain when applied topically, and demonstrating leukemic cell-killing capabilities in vitro.</p>Formule :C10H18ODegré de pureté :97.44% - 97.44%Couleur et forme :SolidMasse moléculaire :154.25Serazapine
CAS :<p>Serazapine is a highly specific serotonin (5-HT2) binding inhibitor with anxiolytic activity for the treatment of anxiety disorders.</p>Formule :C22H23N3O2Degré de pureté :98.71% - 99.57%Couleur et forme :SolidMasse moléculaire :361.44Donitriptan hydrochloride
CAS :<p>Donitriptan hydrochloride (Donitriptan monohydrochloride) is a potent, high efficacy agonist of 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectively</p>Formule :C23H26ClN5O2Degré de pureté :99.8% - 99.86%Couleur et forme :SolidMasse moléculaire :439.94Zicronapine fumarate
CAS :<p>Zicronapine fumarate, an antipsychotic, targets D1/D2 & 5-HT2A receptors; may treat neuropsychiatric conditions.</p>Formule :C26H31ClN2O4Couleur et forme :SolidMasse moléculaire :470.99Alosetron
CAS :<p>Alosetron, a 5-HT3 antagonist, is used for the management of severe diarrhea-predominant irritable bowel syndrome (IBS) in women only.</p>Formule :C17H18N4ODegré de pureté :98%Couleur et forme :Crystalline PowderMasse moléculaire :294.362-Methyl-N,N-dimethyltryptamine
CAS :<p>2-Methyl-N,N-dimethyltryptamine (2,N,N-TMT, compound 15) exhibits binding affinity for the serotonin (5-HT) receptor, with a pA2 value of 6.04. It plays a significant role in neurological disease research.</p>Formule :C13H18N2Couleur et forme :SolidMasse moléculaire :202.3Neocarzinostatin
CAS :<p>Neocarzinostatin is an effective DNA-damaging, anti-tumor antibiotic.</p>Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :N/ASB 216641
CAS :<p>SB 216641 is a 5-HT (1B/1D) antagonist with anxiolytic activity for the study of anxiety disorders and depression.</p>Formule :C28H30N4O4Degré de pureté :98.09%Couleur et forme :SolidMasse moléculaire :486.56Cianopramine hydrochloride
CAS :<p>Cianopramine hydrochloride is a bio-active chemical.</p>Formule :C20H24ClN3Couleur et forme :SolidMasse moléculaire :341.88AL 34662
CAS :<p>AL 34662 is a selective and potent 5-HT2A receptor agonist with IC50s of 0.77 nM and 1.5 nM for rat and human 5-HT2 receptors, respectively.AL 34662 is also a</p>Formule :C10H13N3ODegré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :191.23Lisuride maleate
CAS :<p>Lisuride maleate is a non-selective dopamine agonist and G-protein-biased 5-HT2A receptor agonist capable of blocking prolactin release.</p>Formule :C24H30N4O5Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :454.52BMY-14802
CAS :<p>BMY-14802 (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) is a selective and orally active sigma-1 antagonist with an IC50 of 112 nM.</p>Formule :C18H22F2N4ODegré de pureté :99.84%Couleur et forme :SoildMasse moléculaire :348.39Pellotine
CAS :<p>Pellotine is an alkaloid isolated from Lophophora. It acts as an inverse agonist of the 5-HT7 receptor (5-HT7 receptor), with an EC50 of 291 nM. Pellotine shows strong affinity for the 5-HT1DR and 5-HT6R, with Ki values of 117 nM and 170 nM, respectively. Additionally, Pellotine reduces intracellular cAMP levels, thereby decreasing neuronal excitability and neurotransmitter release.</p>Formule :C13H19NO3Couleur et forme :SolidMasse moléculaire :237.2955-HT2A receptor agonist-5
CAS :<p>5-HT2A receptor agonist-5 (compound I-3) is a potent 5-HT2A agonist with a Ki value of 0.017 µM and exhibits antidepressant activity.</p>Formule :C23H29N3OCouleur et forme :SolidMasse moléculaire :363.5Asenapine citrate
CAS :<p>Asenapine citrate: atypical antipsychotic for schizophrenia, bipolar disorder; targets serotonin, adrenoceptors, dopamine, histamine (pKi: 8.2-10.5).</p>Formule :C23H24ClNO8Couleur et forme :SolidMasse moléculaire :477.895-HT5AR/5-HT6R ligand-1
<p>5-HT5AR/5-HT6R ligand-1 (Compound PP10) is a ligand for serotonin receptors, exhibiting high affinity for the 5-HT5A and 5-HT6 receptors with Ki values of 59 nM and 96 nM, respectively. It possesses some antiproliferative activity against tumor cells and can be utilized in cancer research.</p>Formule :C25H30N4O2SCouleur et forme :SolidMasse moléculaire :450.6Minaprine
CAS :<p>Minaprine is a reversible inhibitor of MAO-A, used in the treatment of various depressive states.</p>Formule :C17H22N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :298.38pCPA methyl ester hydrochloride
CAS :<p>pCPA methyl ester HCl inhibits tryptophan hydroxylase, 5-HT synthesis, crosses blood-brain barrier, lowers central 5-HT.</p>Formule :C10H13Cl2NO2Degré de pureté :99.73% - 99.88%Couleur et forme :SolidMasse moléculaire :250.12Galanin (1-15) (porcine, rat)
CAS :<p>N-terminal galanin fragment used to mediate central cardiovascular effects</p>Formule :C72H105N19O20Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1556.72
