récepteur 5-HT
Les récepteurs 5-HT, également connus sous le nom de récepteurs de la sérotonine, sont un groupe de récepteurs couplés aux protéines G (GPCR) qui médiatisent les effets de la sérotonine, un neurotransmetteur impliqué dans la régulation de l'humeur, l'anxiété, le sommeil, l'appétit et d'autres processus physiologiques. Ces récepteurs sont divisés en plusieurs sous-types, chacun ayant des fonctions et des propriétés pharmacologiques distinctes. Les modulateurs des récepteurs 5-HT sont largement étudiés pour leurs rôles dans le traitement de la dépression, des troubles anxieux et d'autres affections neuropsychiatriques. Chez CymitQuimica, nous offrons une gamme de modulateurs des récepteurs 5-HT de haute qualité pour soutenir vos recherches en neuropharmacologie, troubles de l'humeur et signalisation GPCR.
1025 produits trouvés pour "récepteur 5-HT"
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meta-Fluoxetine (hydrochloride)
CAS :meta-Fluoxetine (hydrochloride) can be used in related research in the field of life sciences. Its product number is T37474 and CAS number is 79088-29-2.Formule :C17H19ClF3NOCouleur et forme :SolidMasse moléculaire :345.79Cabergoline
CAS :Cabergoline (FCE-21336), an ergot-derived dopamine D2-like agonist, targets D2/D3/5-HT2B, normalizes prolactin, controls pituitary tumors.
Formule :C26H37N5O2Degré de pureté :97.69% - 99.86%Couleur et forme :White Crystalline SolidMasse moléculaire :451.6Litoxetine HCl
Litoxetine HCl, an SSRI and 5-HT antagonist, treats urinary incontinence and relaxes rat oesophageal muscles without antimuscarinic effects.Formule :C16H20ClNODegré de pureté :98.97% - 99.9%Couleur et forme :SoildMasse moléculaire :277.79Ref: TM-T67956L
1mg92,00€1mL*10mM (DMSO)197,00€5mg207,00€10mg309,00€25mg527,00€50mg755,00€100mg1.044,00€Triazolomethylindole-3-acetic acid
CAS :Triazolomethylindole-3-acetic acid is a metabolite of Rizatriptan, which acts as an agonist for the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D.Formule :C13H12N4O2Couleur et forme :SolidMasse moléculaire :256.26Isobutyryl-L-carnitine
CAS :Isobutyryl-L-carnitine is a member of the class of compounds known as acylcarnitines. Isobutyryl-L-carnitine is a product of the acyl-CoA dehydrogenases.Formule :C11H21NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :231.29Femoxetine
CAS :Femoxetine: antidepressant, enhances morphine, inhibits MAO-A/B, boosts mice's exercise capacity.Formule :C20H25NO2Degré de pureté :99.1% - 99.35%Couleur et forme :SolidMasse moléculaire :311.42(R,R)-Palonosetron Hydrochloride
CAS :(R,R)-Palonosetron Hydrochloride is the active enantiomer of PalonosetronFormule :C19H25ClN2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :332.87rac Desmethyl Citalopram Hydrochloride
CAS :rac Desmethyl Citalopram Hydrochloride is a 5-hydroxy tryptamine uptake inhibitor with IC50 value of 0.013 μM.Formule :C19H20ClFN2ODegré de pureté :99.24%Couleur et forme :SolidMasse moléculaire :346.835-HT6 inverse agonist 1
CAS :5-HT6 inverse agonist 1 (Compound 33) is an antagonist of the 5-HT6 receptor with a Ki of 23 nM and a Kb of 6.62 nM. This compound can inhibit 5-HT6R-mediated Cdk5 and mTOR signaling pathways and reduce tactile allodynia induced by spinal nerve ligation (SNL) in rat models.Formule :C22H22Cl2FN3O3SCouleur et forme :SolidMasse moléculaire :498.4Fabesetron
CAS :Fabesetron (FK1052): oral dual antagonist for 5-HT3/5-HT4 receptors. Aids in managing acute and delayed chemo-induced emesis.
Formule :C18H19N3OCouleur et forme :SolidMasse moléculaire :293.37Zalospirone
CAS :Zalospirone is a 5-HT1A receptor agonist that can be used to study anxiety disorders and major depressive disorder.Formule :C24H29N5O2Degré de pureté :98.24% - 99.82%Couleur et forme :SolidMasse moléculaire :419.52HTR2A antagonist 1
HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.Formule :C35H43Cl2F2N5O4Couleur et forme :SolidMasse moléculaire :706.65PSEM 308 hydrochloride
PSAM agonist targeting PSAML141F-GlyR and related ion channels in mice; ideal concentration ≤5 mg/kg; plasmids at Addgene.Couleur et forme :Solid5-HT6R antagonist 6
5-HT6R antagonist 6 (Compound PP15) exhibits high affinity and selectivity for the 5-HT6R receptor, with a Ki of 42 nM. It demonstrates weak antiproliferative activity on tumor cells and low toxicity toward normal cells. 5-HT6R antagonist 6 is applicable in tumor research.Formule :C24H26N4O2SCouleur et forme :SolidMasse moléculaire :434.55Serazapine
CAS :Serazapine is a highly specific serotonin (5-HT2) binding inhibitor with anxiolytic activity for the treatment of anxiety disorders.
Formule :C22H23N3O2Degré de pureté :98.71% - 99.57%Couleur et forme :SolidMasse moléculaire :361.445-MeO-pyr-T
CAS :5-MeO-pyr-T (5-Methoxy pyrrolidinyltryptamine) acts as a 5-HT1AR agonist, exhibiting Ki values of 0.577 μM and 373 μM for 5-HT1AR and 5-HT2AR, respectively. It inhibits the reuptake of 5-HT and triggers its release. Additionally, 5-MeO-pyr-T can induce reduced motor activity.Formule :C15H20N2OCouleur et forme :SolidMasse moléculaire :244.33Palonosetron N-oxide
CAS :Palonosetron N-oxide: metabolite and potential impurity of 5-HT3 antagonist palonosetron; forms under oxidative stress.Formule :C19H24N2O2Couleur et forme :SolidMasse moléculaire :312.4134-Butyl-α-agarofuran
CAS :4-Butyl-alpha-agarofuran, a Gharu-wood derivative, is an anxiolytic, antidepressant, and aids neurological research.Formule :C18H30OCouleur et forme :SolidMasse moléculaire :262.432-Methyl-N,N-dimethyltryptamine
CAS :2-Methyl-N,N-dimethyltryptamine (2,N,N-TMT, compound 15) exhibits binding affinity for the serotonin (5-HT) receptor, with a pA2 value of 6.04. It plays a significant role in neurological disease research.Formule :C13H18N2Couleur et forme :SolidMasse moléculaire :202.3Iloperidone metabolite P95
CAS :Iloperidone metabolite P95, a non-brain penetrating compound, binds 5-HT2A, α1-, α2B-, α2C-receptors with Ki of 7.08-83.18 nM.Formule :C23H25FN2O5Couleur et forme :SolidMasse moléculaire :428.46AL 34662
CAS :AL 34662 is a selective and potent 5-HT2A receptor agonist with IC50s of 0.77 nM and 1.5 nM for rat and human 5-HT2 receptors, respectively.AL 34662 is also aFormule :C10H13N3ODegré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :191.23(Iso)-Landipirdine
CAS :(Iso)-Landipirdine((Iso)-RO5025181) is a selective and potent 5-HT6R antagonist.Formule :C18H19FN2O3SDegré de pureté :98.94%Couleur et forme :SoildMasse moléculaire :362.42LY-426965 hydrochloride
CAS :LY-426965 hydrochloride is a bioactive chemical.Formule :C28H39ClN2O2Couleur et forme :SolidMasse moléculaire :471.07Pellotine
CAS :Pellotine is an alkaloid isolated from Lophophora. It acts as an inverse agonist of the 5-HT7 receptor (5-HT7 receptor), with an EC50 of 291 nM. Pellotine shows strong affinity for the 5-HT1DR and 5-HT6R, with Ki values of 117 nM and 170 nM, respectively. Additionally, Pellotine reduces intracellular cAMP levels, thereby decreasing neuronal excitability and neurotransmitter release.Formule :C13H19NO3Couleur et forme :SolidMasse moléculaire :237.295pCPA methyl ester hydrochloride
CAS :pCPA methyl ester HCl inhibits tryptophan hydroxylase, 5-HT synthesis, crosses blood-brain barrier, lowers central 5-HT.
Formule :C10H13Cl2NO2Degré de pureté :99.73% - 99.88%Couleur et forme :SolidMasse moléculaire :250.12Galanin (1-15) (porcine, rat)
CAS :N-terminal galanin fragment used to mediate central cardiovascular effectsFormule :C72H105N19O20Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1556.72Quetiapine-d4 fumarate
CAS :Deuterium-labeled Quetiapine fumarate; an antidepressant and anxiolytic 5-HT agonist, dopamine antagonist.Formule :C25H29N3O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :503.61isomer-Cilansetron
CAS :isomer-Cilansetron is an isomer of Cilansetron.Formule :C20H21N3ODegré de pureté :99.92% - 99.96%Couleur et forme :SoildMasse moléculaire :319.4Mirtazapine N-oxide
CAS :Mirtazapine N-oxide, a mirtazapine metabolite, is produced by CYP1A2 and CYP3A4 in human liver.Formule :C17H19N3OCouleur et forme :SolidMasse moléculaire :281.3594-fluoro MBZP
CAS :4-fluoro MBZP is a novel psychoactive substance in the phenylpiperazine class, utilized for studies on the 5-HT2 receptors in the central nervous system.Formule :C12H17FN2Couleur et forme :SolidMasse moléculaire :208.28Xylamidine
CAS :Xylamidine is a biochemical.Formule :C19H24N2O2Couleur et forme :SolidMasse moléculaire :312.41N-Desmethyl Pimavanserin
CAS :N-Desmethyl Pimavanserin (AC-279) is the active metabolite of Pimavanserin and is used in the treatment of insomnia and other sleep disorders.Formule :C24H32FN3O2Degré de pureté :98.02%Couleur et forme :SolidMasse moléculaire :413.53FFN246
CAS :FFN246, a fluorescent probe, concurrently targets the serotonin transporter (SERT) and vesicular monoamine transporter 2 (VMAT2), exhibiting excitation andFormule :C15H13FN2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :256.27Lisuride maleate
CAS :Lisuride maleate is a non-selective dopamine agonist and G-protein-biased 5-HT2A receptor agonist capable of blocking prolactin release.Formule :C24H30N4O5Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :454.52Ref: TM-T8775
1mg204,00€5mg627,00€1mL*10mM (DMSO)627,00€10mg898,00€25mg1.346,00€50mg1.745,00€100mg2.382,00€BMY-14802
CAS :BMY-14802 (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) is a selective and orally active sigma-1 antagonist with an IC50 of 112 nM.Formule :C18H22F2N4ODegré de pureté :99.84%Couleur et forme :SoildMasse moléculaire :348.39Ref: TM-T67739
2mg35,00€5mg52,00€1mL*10mM (DMSO)58,00€10mg90,00€25mg164,00€50mg259,00€100mg383,00€200mg545,00€Asenapine citrate
CAS :Asenapine citrate: atypical antipsychotic for schizophrenia, bipolar disorder; targets serotonin, adrenoceptors, dopamine, histamine (pKi: 8.2-10.5).Formule :C23H24ClNO8Couleur et forme :SolidMasse moléculaire :477.89Desmethyl Mirtazapine (hydrochloride)
CAS :Desmethyl mirtazapine is a metabolite of the antidepressant mirtazapine.1It is formed from mirtazapine by the cytochrome P450 (CYP) isoform CYP3A4.Formule :C16H18ClN3Couleur et forme :SolidMasse moléculaire :287.79Oxatomide
CAS :Oxatomide: Dual H1/P2X7 antagonist, antihistamine, anti-allergic, treats immune diseases, IC50: 0.95 μM (P2X7), 0.43 μM (5-HT).Formule :C27H30N4ODegré de pureté :99.28% - 99.72%Couleur et forme :White PowderMasse moléculaire :426.55Ref: TM-T19839
1mg35,00€5mg75,00€1mL*10mM (DMSO)84,00€10mg114,00€25mg222,00€50mg356,00€100mg557,00€500mg1.153,00€(R)-Citalopram oxalate
CAS :(R)-Citalopram oxalate is a weak selective serotonin reuptake inhibitor (SSRI) that antagonises its S-isomer (escitalopram), anticonvulsant and antidepressant
Formule :C22H23FN2O5Degré de pureté :99.76%Couleur et forme :White SolidMasse moléculaire :414.43LEK 8804
CAS :LEK 8804 is a 5-HT(2) receptor antagonist and 5-HT(1A) receptor agonist.Formule :C19H19N3OCouleur et forme :SolidMasse moléculaire :305.37R 50595
CAS :R 50595 is a selective non-competitive cisapride antagonist.Formule :C30H35Cl2F2N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :594.52HDAC6-IN-49
HDAC6-IN-49 (Compound 3) is an inhibitor of HDAC, with IC50 values of 0.012 and 0.735 µM against HDAC6 and HDAC1, respectively. Additionally, it inhibits MAO-B, cholinesterase (ChE), histamine receptor (H3R), and serotonin 6 receptor (5-HT6R). HDAC6-IN-49 exhibits neuroprotective effects in SH-SY5Y cells and enhances cognitive functions and motor abilities in fruit fly models of Parkinson's disease and C. elegans models of Alzheimer's disease.Couleur et forme :Odour Solid4-Chloromethamphetamine hydrochloride
CAS :4-Chloromethamphetamine hydrochloride is a novel psychoactive substance belonging to the amphetamine class.Formule :C10H15Cl2NCouleur et forme :SolidMasse moléculaire :220.141,8-Cineole
CAS :Eucalyptol, a natural monoterpenoid and cyclic ether found in eucalyptus species, effectively controls excessive airway mucus secretion and asthma by inhibiting pro-inflammatory cytokines. It serves as an efficacious treatment for non-purulent sinusitis, reducing inflammation and pain when applied topically, and demonstrating leukemic cell-killing capabilities in vitro.Formule :C10H18ODegré de pureté :97.44% - 97.44%Couleur et forme :SolidMasse moléculaire :154.25Alverine hydrochloride
CAS :Alverine hydrochloride is a parasympatholytic.Formule :C20H28ClNCouleur et forme :SolidMasse moléculaire :317.9Mosapride citrate dihydrate
CAS :Mosapride Citrate, a 5-HT4 agonist, boosts gut movement by enhancing acetylcholine release.Formule :C27H35ClFN3O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :632.04Tiflucarbine
CAS :Tiflucarbine is a potential non-selective 5-HT agonist with antidepressant activity.Tiflucarbine dose-dependently increased the specific activity of solubleFormule :C16H17FN2SDegré de pureté :97.71%Couleur et forme :SolidMasse moléculaire :288.38SB 699551
CAS :SB 699551 is a selective 5-HT5A antagonist (Ki=6.31 nM) that enhances 5-HT neuronal function. It inhibits SERT (Ki=25.12 nM),inhibit breast cancer.Formule :C34H45N3ODegré de pureté :99.83%Couleur et forme :SoildMasse moléculaire :511.74Ref: TM-T23325L
1mg190,00€5mg471,00€10mg662,00€25mg1.036,00€50mg1.429,00€100mg1.821,00€200mg2.489,00€DOAM
CAS :DOAM is an antagonist of the 5-HT2 receptor.Formule :C16H27NO2Couleur et forme :SolidMasse moléculaire :265.395-methoxy-α-Ethyltryptamine
CAS :5-Methoxy-alpha-ethyltryptamine is a psychoactive substance that can cause various effects. It belongs to the tryptamine chemical class and can be used for various psychoactive and stimulant effects.
Formule :C13H18N2ODegré de pureté :98.25%Couleur et forme :SolidMasse moléculaire :218.29
