COX
Les inhibiteurs de la cyclooxygénase (COX) sont des composés qui bloquent l'activité des enzymes COX, impliquées dans la production de prostaglandines, des médiateurs clés de l'inflammation et de la douleur. En neurosciences, les inhibiteurs de la COX sont étudiés pour leur potentiel à réduire la neuroinflammation, qui est impliquée dans diverses maladies neurodégénératives telles que la maladie d'Alzheimer, la maladie de Parkinson et la sclérose en plaques. En inhibant la COX, ces composés peuvent aider à atténuer les processus inflammatoires dans le cerveau et à protéger contre les lésions neuronales. Chez CymitQuimica, nous fournissons une gamme d'inhibiteurs de la COX pour soutenir vos recherches sur la neuroinflammation, la gestion de la douleur et les maladies neurodégénératives.
561 produits trouvés pour "COX"
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CAFESTOL
CAS :<p>Cafestol, an ERK inhibitor, suppresses PGE2 and COX-2 by blocking NF-kB in LPS-stimulated RAW264.7 cells.</p>Formule :C20H28O3Degré de pureté :97.06% - 99.08%Couleur et forme :SolidMasse moléculaire :316.43NS-398
CAS :<p>NS-398 (N-(2-cyclohexyloxy-4-nitrophenyl)methane sulfonamide) is a COX-2 inhibitor wih anti-inflammatory activity.</p>Formule :C13H18N2O5SDegré de pureté :99% - >99.99%Couleur et forme :SolidMasse moléculaire :314.36TFAP
CAS :<p>TFAP (N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide) is a selective cyclooxygenase-1 (COX-1) inhibitor</p>Formule :C13H10F3N3ODegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :281.23Revaprazan hydrochloride
CAS :<p>Revaprazan hydrochloride (YH1885) is the hydrochloride salt form of a lipophilic, weak base with potassium-competitive acid blocking (P-CAB) activity.</p>Formule :C22H24ClFN4Degré de pureté :99.62% - 99.91%Couleur et forme :SolidMasse moléculaire :398.9Byakangelicol
CAS :<p>Byakangelicol may reduce P-gp at BBB and has anti-inflammatory effects by hindering COX-2 and PGE2 in A549 cells.</p>Formule :C17H16O6Degré de pureté :98.78% - 99.55%Couleur et forme :SolidMasse moléculaire :316.31Compound Lup-20(29)-en-3-yl acetate
<p>Lupeol acetate, a derivative of Lupeol, inhibits the progression of rheumatoid arthritis by downregulating TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B.</p>Formule :C32H52O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :468.75N-tert-butyl-α-Phenylnitrone
CAS :<p>N-tert-butyl-α-Phenylnitrone ((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) inhibits COX2 catalytic activity.</p>Formule :C11H15NODegré de pureté :99.46% - 99.84%Couleur et forme :SolidMasse moléculaire :177.24CAY10404
CAS :<p>CAY10404: potent COX-1/2 inhibitor; blocks PKB/Akt, MAPK pathways; triggers NSC-LC apoptosis; analgesic, anti-inflammatory, anti-cancer.</p>Formule :C17H12F3NO3SDegré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :367.34Tinoridine hydrochloride
CAS :<p>Tinoridine HCl is an NSAID that inhibits lipid peroxides and renin release, unlike indomethacin and corticosteroids.</p>Formule :C17H21ClN2O2SDegré de pureté :97.49%Couleur et forme :SolidMasse moléculaire :352.88Isofraxidin
CAS :<p>Isofraxidin combats leukemia, ALI, and inflammation by modulating ROS, COX-2, PGE2, TNF-α, and p38/ERK1/2 pathways.</p>Formule :C11H10O5Degré de pureté :99.51% - ≥95%Couleur et forme :SolidMasse moléculaire :222.19Tolmetin
CAS :<p>Tolmetin (Tolectin) NSAID; acts as a cyclooxygenase inhibitor; classified as an anti-inflammatory.</p>Formule :C15H15NO3Degré de pureté :99.74% - >99.99%Couleur et forme :Off-White Crystalline PowerMasse moléculaire :257.28[10]-Shogaol
CAS :<p>[10]-Shogaol (10-Shogaol) is an extract from ginger displaying antioxidant activity. It also may contain hypolipidemic and insulin-sensitizing effects.</p>Formule :C21H32O3Degré de pureté :97.64% - 98.65%Couleur et forme :SolidMasse moléculaire :332.48α-Spinasterol
CAS :<p>α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects.</p>Formule :C29H48ODegré de pureté :97.03% - 99.58%Couleur et forme :SolidMasse moléculaire :412.69Mofezolac
CAS :<p>Mofezolac (formerly known as Disopain or N-22) is a highly selective COX-1 (cyclooxygenase-1) inhibitor with COXs selectivity index > 6000</p>Formule :C19H17NO5Degré de pureté :99.29%Couleur et forme :SolidMasse moléculaire :339.34Firocoxib
CAS :<p>Firocoxib (ML 1785713) is a selective non-steroidal inhibitor of cycooxygenase-2 (COX-2) (IC50 of 0.13 μM), with anti-inflammatory for use in dogs and horses.</p>Formule :C17H20O5SDegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :336.4Parecoxib
CAS :<p>Parecoxib (SC 69124) is an effective and selective COX-2 inhibitor.</p>Formule :C19H18N2O4SDegré de pureté :99.71% - 99.78%Couleur et forme :SolidMasse moléculaire :370.42Tazofelone
CAS :<p>Tazofelone (LY-213829) is a NSAID used for the treatment of inflammatory bowel disease.</p>Formule :C18H27NO2SDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :321.48(E)-Ethyl p-methoxycinnamate
CAS :<p>1. (E)-Ethyl p-methoxycinnamate (EPMC) is an anticarcinogenic agent. 2. (E)-Ethyl p-methoxycinnamate (EPMC) is a glutathion S tranferase inhibitor.</p>Formule :C12H14O3Degré de pureté :97.43%Couleur et forme :SolidMasse moléculaire :206.24RK33
CAS :<p>"RK33 is a DDX3 inhibitor causing G1 arrest, apoptosis, and radiation sensitization in DDX3-overexpressing cells."</p>Formule :C23H20N6O3Degré de pureté :99.04% - 99.72%Couleur et forme :SolidMasse moléculaire :428.44Cis-5-Dodecenoic Acid
CAS :<p>Cis-5-Dodecenoic Acid is a monounsaturated fatty acid that has a C12 chain as a backbone and a cis double bond at the C5 position.</p>Formule :C12H22O2Degré de pureté :98% - 99.37%Couleur et forme :SolidMasse moléculaire :198.3Madecassic acid
CAS :<p>Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.</p>Formule :C30H48O6Degré de pureté :98.80% - 99.69%Couleur et forme :SolidMasse moléculaire :504.7Gnetol
CAS :<p>Gnetol inhibits butyrylcholinesterase (IC50: 1.3 μM), tyrosinase, melanin synthesis in B16 cells, and AA-induced platelet aggregation.</p>Formule :C14H12O4Degré de pureté :98.55% - ≥95%Couleur et forme :SolidMasse moléculaire :244.24Columbin
CAS :<p>Columbin: anti-inflammatory, prevents colon cancer, inhibits PLA2 in RBC dose-dependently.</p>Formule :C20H22O6Degré de pureté :99.34% - 99.74%Couleur et forme :SolidMasse moléculaire :358.39S-(+)-Marmesin
CAS :<p>S-(+)-Marmesin (marmesin) is a coumarin originally isolated from the mature bark of A. marmelos,exhibiting COX-2/5-LOX dual inhibitory activity.</p>Formule :C14H14O4Degré de pureté :98.00% - ≥98%Couleur et forme :SolidMasse moléculaire :246.26Losartan Carboxaldehyde
CAS :<p>Losartan Carboxaldehyde is an endothelial cyclooxygenase (COX)-2 inhibitor.</p>Formule :C22H21ClN6ODegré de pureté :99.1%Couleur et forme :SolidMasse moléculaire :420.89Esculentoside A
CAS :<p>Esculentoside A dampens inflammation in ALI, modulates T cells, and could treat autoimmune diseases and BXSB mice by adjusting cytokines and renal cells.</p>Formule :C42H66O16Degré de pureté :98% - 99.85%Couleur et forme :SolidMasse moléculaire :826.96Isoorientin
CAS :<p>Isoorientin (Homoorientin) has antioxidant activity.</p>Formule :C21H20O11Degré de pureté :98.84% - 99.93%Couleur et forme :SolidMasse moléculaire :448.38Psoralidin
CAS :<p>Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally.</p>Formule :C20H16O5Degré de pureté :98% - 99.61%Couleur et forme :SolidMasse moléculaire :336.342,5-Di-tert-butylhydroquinone
CAS :<p>2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.</p>Formule :C14H22O2Degré de pureté :97.11%Couleur et forme :PelletslargecrystalsMasse moléculaire :222.32(+)-Catechin Hydrate
CAS :<p>(+)-Catechin Hydrate is an antioxidant flavonoid of plant origin; a free radical scavenger, preventing free radical-mediated damage in a variety of biological</p>Formule :C15H16O7Degré de pureté :99.03% - 99.96%Couleur et forme :SolidMasse moléculaire :308.28Chlorotrianisene
CAS :<p>Chlorotrianisene, a synthetic SERM, is orally active, lipophilic, and has estrogenic and antiestrogenic effects.</p>Formule :C23H21ClO3Degré de pureté :98.88% - 99.03%Couleur et forme :Crystals From Methanol Physical Description Small White Crystals Or White Powder Softens At 226°F Odorless (Ntp 1992)Masse moléculaire :380.86Avicularin
CAS :<p>Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.</p>Formule :C20H18O11Degré de pureté :97.02% - 99.94%Couleur et forme :White PowderMasse moléculaire :434.35[8]-Shogaol
CAS :<p>[8]-Shogaol is a component of ginger and maintains anti-inflammatory activity as a cyclooxygenase-2 inhibitor.</p>Formule :C19H28O3Degré de pureté :97.01%Couleur et forme :SolidMasse moléculaire :304.42Diclofenac Potassium
CAS :<p>Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.</p>Formule :C14H10Cl2KNO2Degré de pureté :99.51%Couleur et forme :White To Yellowish Crystalline PowderMasse moléculaire :334.24Lumiracoxib
CAS :<p>Lumiracoxib (Prexige) is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. Phase 4.</p>Formule :C15H13ClFNO2Degré de pureté :96.64% - 99.77%Couleur et forme :Pale Yellow SolidMasse moléculaire :293.72(-)-Catechin gallate
CAS :<p>(-)-Catechin gallate inhibits 6PGD, IDH, Beta-secretase, and fights chloroquine-sensitive/resistant Plasmodium falciparum.</p>Formule :C22H18O10Degré de pureté :97.74% - >99.99%Couleur et forme :SolidMasse moléculaire :442.37Adelmidrol
CAS :<p>Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.</p>Formule :C13H26N2O4Degré de pureté :99.35% - 99.73%Couleur et forme :SolidMasse moléculaire :274.367,3',4'-Tri-O-methylluteolin
CAS :<p>7,3',4'-Tri-O-methylluteolin is anti-inflammatory, antibacterial, antifungal, and has moderate antitrypanosomal effects (MIC 19.0 ug/ml).</p>Formule :C18H16O6Degré de pureté :98.66% - 99.79%Couleur et forme :SolidMasse moléculaire :328.32sphondin
CAS :<p>Sphondin inhibits IL-1beta, reduces COX-2 and PGE(2) in A549 cells, and has anticonvulsant, anti-inflammatory, anti-proliferative properties.</p>Formule :C12H8O4Degré de pureté :99.9% - ≥95%Couleur et forme :SolidMasse moléculaire :216.19Ginsenoside Rb3
CAS :<p>Ginsenoside Rb3 (Gypenoside IV) is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB transcriptional activity.</p>Formule :C53H90O22Degré de pureté :98% - 99.98%Couleur et forme :SolidMasse moléculaire :1079.27SC-58125
CAS :<p>SC-58125 is a selective cyclooxygenase 2 (COX-2) inhibitor. SC-58125 exhibits antitumor activity, and also inhibits oedema at sites of inflammation.</p>Formule :C17H12F4N2O2SDegré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :384.35Roburic acid
CAS :<p>Roburic acid and phenethyl-trans-ferulate inhibit COX-1 and COX-2.</p>Formule :C30H48O2Degré de pureté :98.765% - 99.88%Couleur et forme :SolidMasse moléculaire :440.7Tinoridine
CAS :<p>Tinoridine is a quinoline derivative analog that acts by inhibiting the production of cyclooxygenase-2 (COX-2).</p>Formule :C17H20N2O2SDegré de pureté :99.08%Couleur et forme :SolidMasse moléculaire :316.42FK 3311
CAS :<p>FK 3311 (COX-2 Inhibitor V) is a cell permeable and orally available sulfonanilide that acts as a COX-2 inhibitor and non-steroidal anti-inflammatory drug (</p>Formule :C15H13F2NO4SDegré de pureté :97.98%Couleur et forme :SolidMasse moléculaire :341.33Propyphenazone
CAS :<p>Propyphenazone: an anti-inflammatory, analgesic, antipyretic pyrazolone; prodrug; COX-2 inhibitor.</p>Formule :C14H18N2ODegré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :230.31Teriflunomide impurity 3
CAS :<p>Teriflunomide impurity 3 (4-Amino-N-(4-trifluoromethylphenyl)benzamide) is a selective COX-1 inhibitor(IC50 of 30 μM).</p>Formule :C14H11F3N2ODegré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :280.25Otenaproxesul
CAS :<p>Otenaproxesul (ATB 346) is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity.</p>Formule :C21H19NO3SDegré de pureté :98.76% - 99.13%Couleur et forme :SolidMasse moléculaire :365.45(-)-Epicatechin
CAS :<p>(-)-Epicatechin (Epicatechin) is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by blocking the nuclear localization</p>Formule :C15H14O6Degré de pureté :98.55% - 98.80%Couleur et forme :SolidMasse moléculaire :290.27Fenoprofen Calcium
CAS :<p>Fenoprofen Calcium is a nonsteroidal, anti-inflammatory antiarthritic agent.</p>Formule :C30H26CaO6Degré de pureté :99.24% - 99.66%Couleur et forme :SolidMasse moléculaire :522.6SC-236
CAS :<p>SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively).</p>Formule :C16H11ClF3N3O2SDegré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :401.79
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