Isofraxidin

CAS : 486-21-5

Ref. TM-T5S0045

Informations sur le produit

• Nom: Isofraxidin
• Synonymes: 6,8-Dimethoxyumbelliferone, Phytodolor, 2H-1-Benzopyran-2-one, 7-hydroxy-6,8-dimethoxy-, 6,8-Dimethoxy-7-hydroxycoumarin, 7-Hydroxy-6,8-dimethoxy-2H-1-benzopyran-2-one, 7-Hydroxy-6,8-dimethoxychromen-2-one, 7-hydroxy-6,8-dimethoxy-2H-chromen-2-one, Coumarin, 7-hydroxy-6,8-dimethoxy-, NSC 324637, Phytodolor, Umbelliferone, 6,8-dimethoxy-
• CAS: 486-21-5

Description

1. Isofraxidin (Phytodolor) protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner. 2. Isofraxidin has a protective effect against LPS-induced ALI, and the protective effect of Isofraxidin seems to result from the inhibition of COX-2 protein expression in the lung, which regulates the production of PGE2. 3. Isofraxidin possesses significant analgesic and anti-inflammatory activities that may be mediated through the regulation of pro-inflammatory cytokines, TNF-α and the phosphorylation of p38 and ERK1/2.

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 222.19
• Formule: C₁₁H₁₀O₅
• Degré de pureté: 99.7%
• Couleur/Forme: Solid