COX
Les inhibiteurs de la cyclooxygénase (COX) sont des composés qui bloquent l'activité des enzymes COX, impliquées dans la production de prostaglandines, des médiateurs clés de l'inflammation et de la douleur. En neurosciences, les inhibiteurs de la COX sont étudiés pour leur potentiel à réduire la neuroinflammation, qui est impliquée dans diverses maladies neurodégénératives telles que la maladie d'Alzheimer, la maladie de Parkinson et la sclérose en plaques. En inhibant la COX, ces composés peuvent aider à atténuer les processus inflammatoires dans le cerveau et à protéger contre les lésions neuronales. Chez CymitQuimica, nous fournissons une gamme d'inhibiteurs de la COX pour soutenir vos recherches sur la neuroinflammation, la gestion de la douleur et les maladies neurodégénératives.
562 produits trouvés pour "COX"
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(-)-Epicatechin
CAS :<p>(-)-Epicatechin (Epicatechin) is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by blocking the nuclear localization</p>Formule :C15H14O6Degré de pureté :98.55% - 98.80%Couleur et forme :SolidMasse moléculaire :290.27Licofelone
CAS :<p>Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis.</p>Formule :C23H22ClNO2Degré de pureté :99.25%Couleur et forme :Yellowish SolidMasse moléculaire :379.88SC-236
CAS :<p>SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively).</p>Formule :C16H11ClF3N3O2SDegré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :401.79Chebulagic acid
CAS :<p>Chebulagic acid, isolated from the Terminalia chebula Retz, is a COX-LOX dual inhibitor.</p>Formule :C41H30O27Degré de pureté :97.82% - 99.8%Couleur et forme :SolidMasse moléculaire :954.66(-)-Epicatechin gallate
CAS :<p>(-)-Epicatechin gallate, a catechin isomer and strong antioxidant, affects membrane proteins and alters gA channel function in bilayers.</p>Formule :C22H18O10Degré de pureté :99.16% - 99.93%Couleur et forme :SolidMasse moléculaire :442.37Flurbiprofen Axetil
CAS :<p>Flurbiprofen Axetil (Lipfen) is an anti-inflammatory used as an analgesic.</p>Formule :C19H19FO4Degré de pureté :97.58% - 98%Couleur et forme :SolidMasse moléculaire :330.35Phenidone
CAS :<p>Phenidone inhibits COX/LOX, reducing rat autoimmune paralysis and lowering blood pressure in hypertensive rats.</p>Formule :C9H10N2ODegré de pureté :97.24%Couleur et forme :White Solid Solid CrystallineMasse moléculaire :162.19Ataquimas
CAS :<p>Ataquimast inhibits IL-5 secretion along with that of TNF-a, IL-4 and GM-CSF from human cells.</p>Formule :C11H13N3ODegré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :203.24Neochlorogenic acid
CAS :<p>Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.</p>Formule :C16H18O9Degré de pureté :99.12% - 99.54%Couleur et forme :White PowderMasse moléculaire :354.31Ibuprofen Lysine
CAS :<p>Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug.</p>Formule :C19H32N2O4Degré de pureté :99.26%Couleur et forme :CoaMasse moléculaire :352.473-TERT-BUTYL-4-HYDROXYANISOLE
CAS :<p>3-tert-Butyl-p-hydroxyanisole is an antioxidant which is produced via water chlorination.</p>Formule :C11H16O2Degré de pureté :99.65%Couleur et forme :White Solid WaxyMasse moléculaire :180.24Diclofenac Epolamine
CAS :<p>Diclofenac Epolamine (DHEP) is a non-steroidal anti-inflammatory agent (NSAID) with analgesic and antipyretic actions.</p>Formule :C20H24Cl2N2O3Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :411.32SC-560
CAS :<p>SC-560 is a member of the diaryl heterocycle class of cyclooxygenase (COX) inhibitors.</p>Formule :C17H12ClF3N2ODegré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :352.74Prim-O-glucosylcimifugin
CAS :<p>Prim-O-glucosylcimifugin (Cimifugin 7-glucoside) can inhibit the proliferation of SMC stimulated by TNF-alpha, increase the proportion of G0/G1 phase.</p>Formule :C22H28O11Degré de pureté :98.57% - 99.92%Couleur et forme :SolidMasse moléculaire :468.45RHC 80267
CAS :<p>RHC 80267 (U-57908) is a selective inhibitor of DAGL (IC50 : 4 μM in canine platelets)</p>Formule :C20H34N4O4Degré de pureté :99.54%Couleur et forme :White SolidMasse moléculaire :394.51ETHYL CAFFEATE
CAS :<p>Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro.</p>Formule :C11H12O4Degré de pureté :97.79%Couleur et forme :SolidMasse moléculaire :208.21Ufenamate
CAS :<p>Ufenamate (Flufenamic acid butyl ester) is an anthranilic acid-based anti-inflammatory drug developed for skin diseases</p>Formule :C18H18F3NO2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :337.34Veratric acid
CAS :<p>Veratric acid (3,4-Dimethoxybenzoic acid) is a simple benzoic acid derived from plants and fruits with anti-oxidant, anti-inflammation and blood pressure-</p>Formule :C9H10O4Degré de pureté :99.44%Couleur et forme :SolidMasse moléculaire :182.17Indomethacin farnesil
CAS :<p>Indomethacin farnesil (Infree) is a prodrug of indomethacin. It acts as a nonsteroidal anti-inflammatory drug (NSAID) and disease-modifying anti-rheumatic drug.</p>Formule :C34H40ClNO4Degré de pureté :97.29%Couleur et forme :SolidMasse moléculaire :562.14N-trans-Feruloyltyramine
CAS :<p>NTF is hepatoprotective, antioxidant, inhibits COX, prevents platelet aggregation, and reduces melanin by downregulating tyrosinase.</p>Formule :C18H19NO4Degré de pureté :99.56% - >99.99%Couleur et forme :SolidMasse moléculaire :313.35Phenethyl ferulate
CAS :<p>Phenethyl ferulate is a chemopreventive against colon cancer, enhancing apoptosis in tumors and inhibiting COX/5-LOX (IC50: 4.35/5.75 μM).</p>Formule :C18H18O4Degré de pureté :99.88% - 99.91%Couleur et forme :SolidMasse moléculaire :298.33(S)-Flurbiprofen
CAS :<p>Esflurbiprofen is an inhibitor of COX-1 and COX-2.</p>Formule :C15H13FO2Degré de pureté :99.99%Couleur et forme :White To Yellowish Crystalline PowderMasse moléculaire :244.26Dehydrodiisoeugenol
CAS :<p>Dehydrodiisoeugenol suppresses COX-2 expression and NF-κB activity, reducing inflammation in LPS-stimulated murine macrophages.</p>Formule :C20H22O4Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :326.39Ketorolac
CAS :<p>Ketorolac (Acuvail) is an NSAID that blocks prostaglandin synthesis, related to heterocyclic acetic acids.</p>Formule :C15H13NO3Degré de pureté :99.68%Couleur et forme :White Crystalline Or White PowderMasse moléculaire :255.27Xanthohumol
CAS :<p>Xanthohumol, also known as 2', 4, 4'-trihydroxy-6'-methoxy-3'-prenylchalcone or desmethylxanthohumol, is a member of the class of compounds known as 3-</p>Formule :C21H22O5Degré de pureté :98.19% - 99.67%Couleur et forme :Orange PowderMasse moléculaire :354.4Loxoprofen sodium (dihydrate)
CAS :<p>Loxoprofen sodium dihydrate: Non-steroidal anti-inflammatory with analgesic, antipyretic, antitumor effects; COX-1/COX-2 inhibitor. IC50: 6.5/13.5 μM.</p>Formule :C15H21NaO5Couleur et forme :SolidMasse moléculaire :304.318Tenidap
CAS :<p>Tenidap (CP-66248) is a selective COX-1 and SLC26A3 inhibitor with anti-inflammatory, analgesic, and anti-rheumatic activities.</p>Formule :C14H9ClN2O3SDegré de pureté :98.56% - 99.42%Couleur et forme :SolidMasse moléculaire :320.75NF-κB/MAPK-IN-1
CAS :<p>NF-κB/MAPK-IN-1 is an NF-κB and MAPK pathway inhibitor. NF-κB/MAPK-IN-1 is used to prevent rheumatoid arthritis (RA).</p>Formule :C27H27NO7Degré de pureté :97.03%Couleur et forme :SolidMasse moléculaire :477.51Bromfenac sodium hydrate
CAS :<p>Bromfenac sodium hydrate (Bromfenac monosodium salt sesquihydrate) is the sodium salt form of bromfenac, a NSAID with analgesic and anti-inflammatory effects.</p>Formule :C15H12BrNO3H2O·NaDegré de pureté :91.85% - 99.65%Couleur et forme :SolidMasse moléculaire :383.17Oxyphenbutazone
CAS :<p>Oxyphenbutazone: Non-selective COX inhibitor, anti-inflammatory, kills dormant Mycobacterium tuberculosis.</p>Formule :C19H20N2O3Degré de pureté :99.41% - 99.88%Couleur et forme :White To Yellowish White Crystalline Powder SolidMasse moléculaire :324.37Meloxicam
CAS :<p>Meloxicam (Metacam) is a Nonsteroidal Anti-inflammatory Drug.</p>Formule :C14H13N3O4S2Degré de pureté :97.09% - 99.60%Couleur et forme :Light Yellow SolidMasse moléculaire :351.40Fenoprofen
CAS :<p>Fenoprofen (LILLY-5385) is a non-steroidal anti-inflammatory compound and a modifier enhancer of the melanocortin receptor, increasing ERK1/2 activation.</p>Formule :C15H14O3Degré de pureté :98.4%Couleur et forme :SolidMasse moléculaire :242.27(S)-(+)-Ibuprofen
CAS :<p>(S)-(+)-Ibuprofen (Dexibuprofen) , is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).</p>Formule :C13H18O2Degré de pureté :99.51% - 99.86%Couleur et forme :Colourless Crystalline SolidMasse moléculaire :206.28Paradol
CAS :<p>Paradol, a spicy compound in ginger, offers anti-cancer, anti-inflammatory, antioxidant, and neuroprotective benefits.</p>Formule :C17H26O3Degré de pureté :98.4% - 98.98%Couleur et forme :SolidMasse moléculaire :278.39Fontolizumab
CAS :<p>Fontolizumab (HuZAF) is a humanised IgG1 monoclonal anti-IFN-gamma (IFN-γ) antibody for the study of Crohn's disease.</p>Degré de pureté :95%Couleur et forme :LiquidMasse moléculaire :150 (kDa)Aspirin DL-lysine
CAS :<p>Aspirin DL-lysine: a water-soluble, injectable NSAID that may also hinder cancer growth.</p>Formule :C15H22N2O6Couleur et forme :Crystalline SolidMasse moléculaire :326.35Cadonilimab
CAS :<p>Cadonilimab (AK104) is a tetravalent PD-1/CTLA-4 bispecific humanised antibody that activates T cells by enhancing IL-2 and IFN-γ secretion.</p>Degré de pureté :95% - 95%Couleur et forme :LiquidImidazole Salicylate
CAS :<p>Imidazole Salicylate, a non-steroidal anti-inflammatory drug, has limited inhibitory effects on prostaglandin synthesis.</p>Formule :C10H10N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :206.2Indometacin Farnesil
CAS :Formule :C34H40ClNO4Degré de pureté :>98.0%(HPLC)Couleur et forme :Light yellow to Yellow to Orange clear liquidMasse moléculaire :562.15Ketorolac-d5
CAS :<p>Ketorolac-d5 is a deuterated compound of ketorolac for isotope tracing. Ketorolac is a non-steroidal anti-inflammatory agent and inhibitor of COX-1 and COX-2.</p>Formule :C15H8D5NO3Degré de pureté :98.99%Couleur et forme :SolidMasse moléculaire :260.3Nepafenac-d5
CAS :<p>Nepafenac D5 is the deuterium labeled Nepafenac, which is a selective inhibitor of COX-2 .</p>Formule :C15H14N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :259.31AHR-10037
CAS :<p>AHR-10037, a NSAID, offers pain relief, fever reduction, safety, and low stomach risk, acting as a prodrug for COX inhibitors.</p>Formule :C15H13ClN2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :288.73Amfenac
CAS :<p>Amfenac promotes apoptosis in ARPE-19 cell culture.</p>Formule :C15H13NO3Couleur et forme :SolidMasse moléculaire :255.27Pelubiprofen
CAS :<p>Pelubiprofen is a non-steroidal anti-inflammatory agent and a COX-2 inhibitor, which effectively reduces PGE(2) production by inhibiting COX activity.</p>Formule :C16H18O3Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :258.31COX-2-IN-2
CAS :<p>COX-2-IN-2 selectively inhibits COX2 (IC50: 0.24 μM); COX-2-IN-1 offers anti-inflammatory and pain relief.</p>Formule :C17H12FN3O2SDegré de pureté :97.62%Couleur et forme :SolidMasse moléculaire :341.36COX-2-IN-26
CAS :<p>COX-2-IN-26: Oral, selective COX-2 inhibitor, low IC50s; anti-inflammatory with GI safety.</p>Formule :C23H21N7OS3Couleur et forme :SolidMasse moléculaire :507.65Loxoprofenol-SRS tromethamine
CAS :<p>Loxoprofenol-SRS tromethamine (HR1405-01), a metabolite of Loxoprofen, is a safe IV NSAID with strong anti-inflammatory and pain relief properties.</p>Formule :C19H31NO6Couleur et forme :SolidMasse moléculaire :369.45COX-2-IN-24
CAS :<p>COX-2-IN-24 is an orally active COX-2 inhibitor (IC50: 0.17 μM) with anti-inflammatory and hypo-ulcerogenic effects.</p>Formule :C24H24BrN5O3S2Couleur et forme :SolidMasse moléculaire :574.51COX-2-IN-18
CAS :<p>COX-2-IN-18 is a potent COX-2 inhibitor similar to Celecoxib, showing promise in cancer research. IC50=0.775μM.</p>Formule :C18H19N3O3S2Couleur et forme :SolidMasse moléculaire :389.49COX-2-IN-14
CAS :<p>COX-2-IN-14 (2a) is a potent, selective COX-2 inhibitor with high affinity and notable anti-inflammatory effects in mice.</p>Formule :C18H18N4O6Couleur et forme :SolidMasse moléculaire :386.364
