PAI-1
Le Plasminogen Activator Inhibitor-1 (PAI-1) est un inhibiteur de la sérine protéase qui régule la fibrinolyse en inhibant l'activateur tissulaire du plasminogène (tPA) et l'urokinase (uPA). Des niveaux élevés de PAI-1 sont associés à un risque accru de thrombose, de maladies cardiovasculaires et de syndrome métabolique. Les inhibiteurs de PAI-1 font l'objet de recherches pour leur potentiel dans le traitement de ces conditions. Chez CymitQuimica, nous proposons des inhibiteurs de PAI-1 pour soutenir vos recherches en hématologie, santé cardiovasculaire et maladies métaboliques.
25 produits trouvés pour "PAI-1"
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Upamostat
CAS :<p>Upamostat is an inhibitor of a serine protease and is a urokinase plasminogen activator (uPA) inhibitor.</p>Formule :C32H47N5O6SDegré de pureté :99.41%Couleur et forme :SolidMasse moléculaire :629.81Angstrom6
CAS :<p>Angstrom6 (A-6 peptide) is an 8 amino acid peptide derived from single chain urokinase fibrinogen activator (scuPA) that interferes with the uPA/uPAR cascade</p>Formule :C39H62N10O15Degré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :910.97CT140
<p>CT140 is a human IgG4 monoclonal antibody (mAb) that specifically targets PAI-1. The suggested isotype control for this compound is Human IgG4 kappa, Isotype Control.</p>Couleur et forme :Odour LiquidGGACK hydrochloride
<p>GGACK (H-Glu-Gly-Arg-CMK) hydrochloride is an irreversible substrate-like inhibitor of the serine protease urokinase-type plasminogen activator (uPA).</p>Formule :C14H26Cl2N6O5Couleur et forme :SolidMasse moléculaire :428.13417Nattokinase
CAS :<p>Nattokinase is a serine protease derived from nattō, oral， fibrinolytic/anticoagulant properties. It degrades fibrin, fibrinolytic substrates, and PAI-1.</p>Couleur et forme :SolidUK140
<p>UK140 is an inhibitor of the urokinase-type plasminogen activator (uPA), with Ki values of 0.20 µM for human uPA (huPA) and 2.79 µM for mouse uPA (muPA). UK140 is applicable in studies related to tumor metastasis.</p>Formule :C72H105N19O25S3Couleur et forme :SolidMasse moléculaire :1732.91Bicyclic UK18
CAS :<p>Bicyclic UK18 is a competitive inhibitor of human urokinase-type plasminogen activator (uPA) with a Ki value of 53 nM.</p>Formule :C77H118N26O25S3Couleur et forme :SolidMasse moléculaire :1904.11UK-371804
CAS :<p>UK-371804: potent uPA blocker; candidate for chronic skin ulcer preclinical studies.</p>Formule :C14H16ClN5O4SDegré de pureté :95.81% - 99.77%Couleur et forme :SolidMasse moléculaire :385.83Loureirin B
CAS :<p>Loureirin B suppresses fibrosis by modulating MMPs/TIMPs, hindering fibroblast growth, and targeting TGF-β1/Smad2/3 pathway.</p>Formule :C18H20O5Degré de pureté :99.33% - 99.86%Couleur et forme :SolidMasse moléculaire :316.35TM5441
CAS :<p>TM5441 is an orally bioavailable fibrinogen activator inhibitor-1 inhibitor that inhibits several cancer cell lines with IC50 values ranging from 13.9 to 51.1 μM.Cost-effective and quality-assured.Cost-effective and quality-assured.</p>Formule :C21H17ClN2O6Degré de pureté :97.62% - 99.09%Couleur et forme :SolidMasse moléculaire :428.82TM5007
CAS :<p>TM5007 is a poent inhibitor of plasminogen activator inhibitor-1 (PAI-1; IC50 of 29 uM).</p>Formule :C24H20N2O6S4Degré de pureté :96.91%Couleur et forme :SolidMasse moléculaire :560.69Tiplaxtinin
CAS :<p>Tiplaxtinin (Tiplasinin)(PAI-039) is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 uM.</p>Formule :C24H16F3NO4Degré de pureté :99.16% - 99.93%Couleur et forme :SolidMasse moléculaire :439.38Toddalolactone
CAS :<p>Toddalolactone ((+)-Toddalolactone) is an anti-inflammatory and analgesic.</p>Formule :C16H20O6Degré de pureté :99.06% - 99.85%Couleur et forme :SolidMasse moléculaire :308.33TM5275 sodium
CAS :<p>TM5275 sodium (TM5275 sodium salt) is an inhibitor of plasminogen activator inhibitor 1 (PAI-1).</p>Formule :C28H27ClN3NaO5Degré de pureté :98.8% - 99.74%Couleur et forme :SolidMasse moléculaire :543.98MDI-2268
CAS :<p>MDI-2268, an inhibitor of plasma kallikrein inhibitor 1 (PAI-1), exhibits strong antithrombotic properties. It plays a role in regulating blood coagulation by promoting fibrinolysis and is applicable in research related to deep vein thrombosis.</p>Formule :C10H10F3N3O3Couleur et forme :SolidMasse moléculaire :277.20SK-216
CAS :<p>SK-216,PAI-1 inhibitor. Reduces tumor angiogenesis. Inhibits VEGF-induced endothelial cell migration. Alleviates pulmonary fibrosis.</p>Formule :C29H29NNa2O6Degré de pureté :98.29%Couleur et forme :SolidMasse moléculaire :533.52UK-371804 HCl
CAS :<p>UK-371804 is a potent and selective urokinase-type plasmogen activator (uPA) inhibitor with excellent enzyme potency (Ki=10 nM) and selectivity profile (2700-</p>Formule :C14H17Cl2N5O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :422.29Diaplasinin
CAS :<p>Diaplasinin (PAI-749) is a potent inhibitor of plasminogen activator inhibitor-1 (PAI-1) with antithrombotic activity, used in cardiovascular disease research.</p>Formule :C32H31N5ODegré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :501.62Aleplasinin
CAS :<p>Aleplasinin (PAZ 417) is a selective and orally active inhibitor of Plasminogen activator inhibitor-1(PAI-1) and a key negative regulator of the fibrinolytic</p>Formule :C28H27NO3Degré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :425.52AZ3976
CAS :<p>AZ3976 is an inhibitor of PAI-1 with an IC50 of 16 μM in a plasma clot lysis assay. AZ3976 displays profibrinolytic activities.</p>Formule :C15H19N5O3Degré de pureté :98.14%Couleur et forme :SolidMasse moléculaire :317.34
