PAI-1
Le Plasminogen Activator Inhibitor-1 (PAI-1) est un inhibiteur de la sérine protéase qui régule la fibrinolyse en inhibant l'activateur tissulaire du plasminogène (tPA) et l'urokinase (uPA). Des niveaux élevés de PAI-1 sont associés à un risque accru de thrombose, de maladies cardiovasculaires et de syndrome métabolique. Les inhibiteurs de PAI-1 font l'objet de recherches pour leur potentiel dans le traitement de ces conditions. Chez CymitQuimica, nous proposons des inhibiteurs de PAI-1 pour soutenir vos recherches en hématologie, santé cardiovasculaire et maladies métaboliques.
31 produits trouvés pour "PAI-1".
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Upamostat
CAS :Upamostat is an inhibitor of a serine protease and is a urokinase plasminogen activator (uPA) inhibitor.Formule :C32H47N5O6SDegré de pureté :99.41%Couleur et forme :White SolidMasse moléculaire :629.81PAI-1-IN-1
CAS :PAI-1-IN-1 is a plasminogen activator inhibitor-1 (PAI-1) inhibitor that affects fibrinolytic activity by modulating PAI-1-mediated inhibition of tPA/uPA.Formule :C23H14ClN2NaO3Degré de pureté :99.42%Masse moléculaire :424.81D-Val-Leu-Lys-AMC TFA
D-Val-Leu-Lys-AMC TFA is a selective fluorescent peptide substrate for plasmin. It is employed for the quantitative assessment of plasmin enzymatic activity. The excitation wavelength is 360-380 nm, and the emission wavelength is 440-460 nm.PAI-1-IN-2
CAS :5-Chloro-2-[[[2-[[3-(furan-2-yl)phenyl]amino]-2-oxoethoxy]acetyl]amino]benzoic acid is an oral PAI-1 inhibitor improving metabolism and hepatic steatosis.Formule :C21H17ClN2O6Degré de pureté :98.78%Masse moléculaire :428.82Nattokinase
CAS :Nattokinase is a serine protease derived from nattō, oral， fibrinolytic/anticoagulant properties. It degrades fibrin, fibrinolytic substrates, and PAI-1.Couleur et forme :Yellow SolidAngstrom6
CAS :Angstrom6 (A-6 peptide) is an 8 amino acid peptide derived from single chain urokinase fibrinogen activator (scuPA) that interferes with the uPA/uPAR cascadeFormule :C39H62N10O15Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :910.9676Bicyclic UK18
CAS :Bicyclic UK18 is a competitive inhibitor of human urokinase-type plasminogen activator (uPA) with a Ki value of 53 nM.Formule :C77H118N26O25S3Couleur et forme :SolidMasse moléculaire :1904.11UK140
UK140 is an inhibitor of the urokinase-type plasminogen activator (uPA), with Ki values of 0.20 µM for human uPA (huPA) and 2.79 µM for mouse uPA (muPA). UK140 is applicable in studies related to tumor metastasis.Formule :C72H105N19O25S3Couleur et forme :SolidMasse moléculaire :1732.91Stromab
Stromab (DS9231; TS-23; CSL-301) is a human-derived IgG1 monoclonal antibody (mAb) that targets SerpinF2. It can be utilized for research in ischemic stroke, pulmonary embolism, myocardial infarction, and thrombosis. The suggested isotype control is Human IgG1 lambda, Isotype Control.6-Aminocaproic acid (Standard)
CAS :6-Aminocaproic acid (Standard) is the standard substance of 6-Aminocaproic acid, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. 6-Aminocaproic acid (EACA) is an antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.Formule :C6H13NO2Couleur et forme :SolidMasse moléculaire :131.1729CDE-096
CAS :CDE-096 is a potent inhibitor of plasminogen activator inhibitor-1 that prevents PAI-1–mediated inactivation of tissue plasminogen activator and urokinase plasminogen activator with nanomolar potency, while maintaining activity against glycosylated and multispecies PAI-1, enabling translational research in fibrinolysis and thrombosis regulation.Formule :C25H20F3NO12Degré de pureté :99.08%Couleur et forme :Yellow SolidMasse moléculaire :583.42Anti-Human SERPINE1 Antibody
Anti-SERPINE1 Antibody targets PAI-1, promoting fibrinolysis and reducing fibrosis by neutralizing its activity, and blocks PAI-1-mediated tumor immune evasion.Degré de pureté :95% - 97.6% (SDS-PAGE); 99.1% (SEC-HPLC)Masse moléculaire :146.07 kDa (Predicted)TM5007
CAS :TM5007 is a poent inhibitor of plasminogen activator inhibitor-1 (PAI-1; IC50 of 29 uM).Formule :C24H20N2O6S4Degré de pureté :96.91%Couleur et forme :SolidMasse moléculaire :560.69UK-371804
CAS :UK-371804: potent uPA blocker; candidate for chronic skin ulcer preclinical studies.Formule :C14H16ClN5O4SDegré de pureté :95.81% - 99.77%Couleur et forme :SolidMasse moléculaire :385.826Loureirin B
CAS :Loureirin B suppresses fibrosis by modulating MMPs/TIMPs, hindering fibroblast growth, and targeting TGF-β1/Smad2/3 pathway.Formule :C18H20O5Degré de pureté :99.33% - 99.86%Couleur et forme :White SolidMasse moléculaire :316.3484Tiplaxtinin
CAS :Tiplaxtinin (Tiplasinin)(PAI-039) is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 uM.Formule :C24H16F3NO4Degré de pureté :99.16% - 99.93%Couleur et forme :SolidMasse moléculaire :439.38Toddalolactone
CAS :Toddalolactone ((+)-Toddalolactone) is an anti-inflammatory and analgesic.Formule :C16H20O6Degré de pureté :99.8% - 99.85%Couleur et forme :SolidMasse moléculaire :308.3264TM5275 sodium
CAS :TM5275 sodium (TM5275 sodium salt) is an inhibitor of plasminogen activator inhibitor 1 (PAI-1).Formule :C28H27ClN3NaO5Degré de pureté :98.8% - 99.74%Couleur et forme :SolidMasse moléculaire :543.98TM5441
CAS :TM5441 is an orally bioavailable fibrinogen activator inhibitor-1 inhibitor that inhibits several cancer cell lines with IC50 values ranging from 13.9 to 51.1 μM.Cost-effective and quality-assured.Cost-effective and quality-assured.Formule :C21H17ClN2O6Degré de pureté :0.998% - 99.23%Couleur et forme :White SolidMasse moléculaire :428.822MDI-2268
CAS :MDI-2268, an inhibitor of plasma kallikrein inhibitor 1 (PAI-1), exhibits strong antithrombotic properties. It plays a role in regulating blood coagulation by promoting fibrinolysis and is applicable in research related to deep vein thrombosis.Formule :C10H10F3N3O3Couleur et forme :SolidMasse moléculaire :277.20
