c-Fms
Les inhibiteurs de c-Fms ciblent le récepteur du facteur de stimulation des colonies-1 (c-Fms), une tyrosine kinase impliquée dans la régulation des macrophages et d'autres cellules immunitaires. La signalisation de c-Fms joue un rôle dans la prolifération, la différenciation et la survie de ces cellules. La dérégulation de c-Fms est associée à des maladies telles que le cancer, les conditions inflammatoires et l'ostéoporose. Chez CymitQuimica, nous proposons des inhibiteurs de c-Fms pour soutenir vos recherches en immunologie, oncologie et maladies inflammatoires.
108 produits trouvés pour "c-Fms"
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CSF1R-IN-2
CAS :CSF1R-IN-2 is an oral-active SRC, MET and c-FMS inhibitor (IC50s: 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively).Formule :C20H20FN7O2Degré de pureté :99.29%Couleur et forme :SolidMasse moléculaire :409.42Lacnotuzumab
CAS :Lacnotuzumab (MCS110) is a humanized monoclonal antibody targeting CSF-1, which can be used in research on retinal diseases.Degré de pureté :>95%Couleur et forme :LiquidMasse moléculaire :144.8 kDaEdicotinib
CAS :Edicotinib (JNJ-527) is a blood-brain permeable, selective CSF-1R inhibitor, with lesser inhibitory effects on KIT and FLT3.Cost-effective and quality-assured.
Formule :C27H35N5O2Degré de pureté :98.58% - 99.72%Couleur et forme :SolidMasse moléculaire :461.6Emactuzumab
CAS :Emactuzumab(RG 7155) is a monoclonal antibody against colony-stimulating factor-1 receptor targeting tumor-associated macrophages (TAMs) Emactuzumab has
Degré de pureté :SDS-PAGE:98.3%;SEC-HPLC:97.3%Couleur et forme :LiquidMasse moléculaire :144.4 kDaMavrilimumab
CAS :Mavrilimumab (CAM 3001), a monoclonal antibody, blocks GM-CSF signaling, potentially reducing inflammation in rheumatoid arthritis.
Degré de pureté :> 95% - > 95%Couleur et forme :LiquidMasse moléculaire :143.2 kDaCSF1R-IN-1
CAS :CSF1R-IN-1 is a CSF1R inhibitor with IC50 of 0.5 nM.Formule :C25H20F3N5O2Degré de pureté :97.02% - 98.56%Couleur et forme :SolidMasse moléculaire :479.45Ref: TM-T10894
1mg88,00€5mg200,00€10mg309,00€25mg522,00€50mg747,00€100mg1.035,00€200mg1.378,00€1mL*10mM (DMSO)219,00€Otilimab
CAS :Otilimab, a humanized monoclonal antibody, blocks GM-CSF to reduce inflammation and may treat severe COVID-19 pneumonia.
Degré de pureté :> 95%Couleur et forme :LiquidMasse moléculaire :142.22 kDaPlonmarlimab
CAS :Plonmarlimab(TJ003234) is an anti-GM-CSF monoclonal antibody with potential antiviral activity for the study of immune disorders and novel coronavirus infectionDegré de pureté :96.2% (SDS-PAGE); 95.4% (SEC-HPLC) - 96.2% (SDS-PAGE); 95.4% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :145.94 kDaSotuletinib hydrochloride
CAS :Sotuletinib hydrochloride (BLZ945 HCl) is a selective, brain-penetrant CSF-1R (c-Fms) inhibitor (IC50=1 nM),for ALS and TNBC.Formule :C20H23ClN4O3SDegré de pureté :98.812%Couleur et forme :SolidMasse moléculaire :434.94PXB17
PXB17 inhibits CSF1R activation (IC50= 1.7 nM) by blocking the PI3K/AKT/mTORC1 signaling pathway. It is effective orally, significantly suppresses the growth of colorectal cancer (CRC), enhances the efficacy of PD-1 monoclonal antibodies (PD-1mAb), and reduces the recurrence of CRC tumors.Formule :C29H35N7O4Masse moléculaire :545.27505CSF1R-IN-17
CSF1R-IN-17 (compound 9) is a potent, selective antagonist of CSF1R, exhibiting an inhibition concentration half-maximum (IC50) of 0.2 nM.Formule :C20H25N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :367.44Adrixetinib TFA
Adrixetinib (TFA) is a protein tyrosine kinase inhibitor that possesses antineoplastic properties [1] [2] [3].Couleur et forme :Odour SolidPyrithyldione
CAS :Pyrithyldione is a sedative-hypnotic agent known to potentially induce agranulocytosis.Formule :C9H13NO2Couleur et forme :SolidMasse moléculaire :167.21cFMS Receptor Inhibitor IV
CAS :cFMS Receptor Inhibitor IV is an inhibitor of c-Fms tyrosine kinase.
Formule :C22H26N4O2Degré de pureté :99.70%Couleur et forme :SolidMasse moléculaire :378.47Antifibrotic agent 1
Antifibrotic agent 1 is an orally active medication designed to treat idiopathic pulmonary fibrosis (IPF). It effectively mitigates IPF-related processes, including TGF-β-induced epithelial-mesenchymal transition (EMT) and fibroblast-to-myofibroblast transition (FMT), as well as profibrotic M2 polarization. Antifibrotic agent 1 selectively inhibits CSF-1R, PDGFR-α, and Src family kinases (SFKs), while sparing VEGFR, FGFR, and Abl to minimize off-target toxicity. In a bleomycin (BLM)-induced pulmonary fibrosis mouse model, it demonstrates strong antifibrotic activity.Formule :C27H23ClN6O2Couleur et forme :SolidMasse moléculaire :498.1571M4205
CAS :M4205 is an inhibitor of c-Kit exhibiting high activity on c-Kit mutations in exons 11, 13, 17.Formule :C29H32N8ODegré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :508.62Ref: TM-T9689
1mg50,00€5mg110,00€10mg170,00€25mg290,00€50mg414,00€100mg572,00€200mg772,00€1mL*10mM (DMSO)122,00€Eflapegrastim
CAS :Eflapegrastim: humanized IgG4 antibody and G-CSF that boosts neutrophils and shortens neutropenia.Couleur et forme :LiquidGimsilumab
CAS :Gimsilumab (MORAb-022) is an anti-c-Fms humanized monoclonal antibody for the study of inflammation and hypoxemia caused by COVID-19.Degré de pureté :99.49% (SEC-HPLC) - 99.49% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :145.8 kDaPLX647 dihydrochloride
CAS :PLX647 dihydrochloride: potent FMS/KIT inhibitor (IC50: 28/16 nM), highly selective, limited FLT3/KDR activity, oral use.Formule :C21H19Cl2F3N4Couleur et forme :SolidMasse moléculaire :455.31AMG-820
AMG-820 is a human antibody targeting CSF-1R, inhibiting the binding of ligands CSF1 and IL34, and preventing subsequent ligand-induced receptor activation. For AMG-820's isotype control, refer to [Human IgG2 kappa, Isotype Control].Couleur et forme :Odour LiquidGENZ-882706(Raceme)
CAS :GENZ-882706(Raceme) is the racemate of GENZ-882706.Formule :C26H25N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :455.51CSF1R Protein, Human, Recombinant
CSF1R Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 55.1 kDa and the accession number is P07333-1.Couleur et forme :Lyophilized PowderMasse moléculaire :55.1 kDa (predicted); 80-90 kDa (reducing condition, due to glycosylation)PLX647
CAS :PLX647 is a highly selective dual FMS/KIT kinase inhibitor (IC50: 28/16 nM).Formule :C21H17F3N4Degré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :382.38Ref: TM-T1925
2mg39,00€5mg57,00€10mg86,00€25mg127,00€50mg178,00€100mg264,00€200mg389,00€1mL*10mM (DMSO)60,00€Anti-CSF1R Antibody (4Y587)
Anti-CSF1R Antibody (4Y587) is a Mouse antibody targeting CSF1R. Anti-CSF1R Antibody (4Y587) can be used in FCM.Couleur et forme :Odour LiquidAnti-CSF1R Antibody (5C535)
Anti-CSF1R Antibody (5C535) is a Rabbit antibody targeting CSF1R. Anti-CSF1R Antibody (5C535) can be used in ELISA.Couleur et forme :Odour LiquidAnti-CSF1R Antibody (1R707)
Anti-CSF1R Antibody (1R707) is a Rabbit antibody targeting CSF1R. Anti-CSF1R Antibody (1R707) can be used in ELISA.Couleur et forme :Odour LiquidAnti-CSF1R Antibody (2I506)
Anti-CSF1R Antibody (2I506) is a Mouse antibody targeting CSF1R. Anti-CSF1R Antibody (2I506) can be used in ELISA.Couleur et forme :Odour LiquidAnti-CSF1R Antibody-FITC (4Y587)
Anti-CSF1R Antibody-FITC (4Y587) is a FITC-conjugated Mouse antibody targeting CSF1R. Anti-CSF1R Antibody-FITC (4Y587) can be used in FCM.Couleur et forme :Odour LiquidAnti-CSF1R Antibody (7V18)
Anti-CSF1R Antibody (7V18) is a Rabbit antibody targeting CSF1R. Anti-CSF1R Antibody (7V18) can be used in ELISA.Couleur et forme :Odour LiquidAnti-CSF1R Antibody (8O797)
Anti-CSF1R Antibody (8O797) is a Mouse antibody targeting CSF1R. Anti-CSF1R Antibody (8O797) can be used in ELISA.Couleur et forme :Odour LiquidAnti-CSF1R Antibody (5B661)
Anti-CSF1R Antibody (5B661) is a Mouse antibody targeting CSF1R. Anti-CSF1R Antibody (5B661) can be used in ELISA,ELISA(Cap).Couleur et forme :Odour LiquidCSF1R Protein, Cynomolgus, Recombinant (His)
M-CSFR/CSF1R/CD115 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag.Couleur et forme :Lyophilized PowderMasse moléculaire :56.3 kDa (predicted). Due to glycosylation, the protein migrates to 75-105 kDa based on Tris-Bis PAGE result.CSF1R Protein, Human, Recombinant (His & Avi), Biotinylated
CSF1R Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag.Couleur et forme :Lyophilized PowderMasse moléculaire :57.76 kDa (predicted); 82.52 kDa (reducing conditions)CSF1R Protein, Human, Recombinant (hFc)
CSF1R Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Couleur et forme :Lyophilized PowderMasse moléculaire :81.2 kDa (predicted)Ref: TM-TMPY-05429
1mg2.931,00€5µg57,00€10µg90,00€20µg126,00€50µg244,00€100µg472,00€200µg691,00€500µg1.488,00€CSF1R Protein, Human, Recombinant (His & Avi), Biotinylated
M-CSFR/CSF1R/CD115 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.Couleur et forme :Lyophilized PowderMasse moléculaire :57.4 kDa (predicted). Due to glycosylation, the protein migrates to 75-105 kDa based on Tris-Bis PAGE result.Ref: TM-TMPK-00415
5µg91,00€10µg150,00€20µg239,00€50µg471,00€100µg779,00€200µg1.410,00€500µg3.018,00€CSF1R Protein, Human, Recombinant (mFc)
CSF1R Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag.Couleur et forme :Lyophilized PowderMasse moléculaire :81.5 kDa (predicted)Ref: TM-TMPY-05264
1mg2.099,00€5µg47,00€10µg65,00€20µg94,00€50µg167,00€100µg334,00€200µg499,00€500µg1.046,00€CSF1R Protein, Human, Recombinant (Domain I&II&III, His)
CSF1R Protein, Human, Recombinant (Domain I&II&III, His) is expressed in HEK293 mammalian cells with His tag.Couleur et forme :Lyophilized PowderMasse moléculaire :31.1 kDa (predicted)CSF1R Protein, Human, Recombinant (hFc & Avi), Biotinylated
CSF1R Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag.Couleur et forme :Lyophilized PowderMasse moléculaire :83.04 kDa (predicted); 110.87 kDa (reducing conditions)CSF1R Protein (Ala299-Glu512), Human, Recombinant (His)
CSF1R Protein (Ala299-Glu512), Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Couleur et forme :Lyophilized PowderMasse moléculaire :25.3 kDa (predicted)CSF1R Protein (Met1-Glu512), Human, Recombinant (His)
CSF1R Protein (Met1-Glu512), Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Degré de pureté :SDS-PAGE: 97.7%; SEC-HPLC: 99.7%Couleur et forme :Lyophilized PowderMasse moléculaire :56 kDa (predicted); 85-95 kDa (reducing condition, due to glycosylation)CSF1R Protein, Human, Recombinant (His & Avi)
M-CSFR/CSF1R/CD115 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag.Couleur et forme :Lyophilized PowderMasse moléculaire :57.4 kDa (predicted). Due to glycosylation, the protein migrates to 75-105 kDa based on Tris-Bis PAGE result.CSF1R Protein, Human, Recombinant (His & GST)
CSF1R Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.Couleur et forme :Lyophilized PowderMasse moléculaire :76 kDa (predicted); 75 kDa (reducing conditions)Dovitinib
CAS :Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.
Formule :C21H21FN6ODegré de pureté :99.35% - 99.92%Couleur et forme :SolidMasse moléculaire :392.43PLX5622
CAS :PLX5622 is a selective, orally active and blood-brain barrier permeable CSF1R inhibitor. PLX5622 induces elimination of microglia. Cost effective and quality assured.Formule :C21H19F2N5ODegré de pureté :98% - 99.97%Couleur et forme :SolidMasse moléculaire :395.41Ref: TM-T7100
1mg43,00€5mg81,00€10mg118,00€25mg230,00€50mg385,00€100mg502,00€200mg710,00€1mL*10mM (DMSO)77,00€OSI-930
CAS :OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.Formule :C22H16F3N3O2SDegré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :443.44PF 477736
CAS :PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Formule :C22H25N7O2Degré de pureté :97.58% - 99.94%Couleur et forme :SolidMasse moléculaire :419.48Nampt-IN-1
CAS :Nampt-IN-1 (LSN3154567) (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with an IC50 of 3.1 nM.Formule :C20H25N3O5SDegré de pureté :99.28% - 99.4%Couleur et forme :SolidMasse moléculaire :419.49Ref: TM-T4376
1mg37,00€2mg49,00€5mg79,00€10mg130,00€25mg245,00€50mg409,00€100mg605,00€1mL*10mM (DMSO)87,00€Seralutinib
CAS :Seralutinib (GB002) is an inhibitor of inhaled PDGFRα and PDGFRβ. It is used in the study for pulmonary arterial hypertension.Formule :C27H27N5O3Degré de pureté :99.09%Couleur et forme :SolidMasse moléculaire :469.54Ref: TM-T8900
1mg47,00€2mg62,00€5mg92,00€10mg137,00€25mg236,00€50mg313,00€100mg497,00€1mL*10mM (DMSO)92,00€GW786034B
CAS :Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.Formule :C21H23N7O2S·HClDegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :473.98GW2580
CAS :GW2580 (SC-203877) is a specific, oral-bioavailable CSF-1R inhibitor for c-FMS.Formule :C20H22N4O3Degré de pureté :99.48% - >99.99%Couleur et forme :SolidMasse moléculaire :366.41PRN1371
CAS :PRN1371 is a specific and potent FGFR1-4 and CSF1R inhibitor (IC50s: 0.6/1.3/4.1/19.3/8.1 nM for FGFR1/2/3/4 and CSF1R).Formule :C26H30Cl2N6O4Degré de pureté :98.65%Couleur et forme :SolidMasse moléculaire :561.46Ref: TM-TQ0015
1mg77,00€2mg100,00€5mg166,00€10mg289,00€25mg492,00€50mg710,00€100mg973,00€1mL*10mM (DMSO)200,00€Sotuletinib
CAS :Sotuletinib (BLZ945) is an orally active, effective and specific CSF-1R inhibitor, >1000-fold selective against its closest receptor tyrosine kinase homologs.Formule :C20H22N4O3SDegré de pureté :97.43% - 99.82%Couleur et forme :SolidMasse moléculaire :398.48Ref: TM-T6119
1mg37,00€5mg79,00€10mg111,00€25mg172,00€50mg216,00€100mg378,00€500mg868,00€1mL*10mM (DMSO)87,00€Ki20227
CAS :Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).Formule :C24H24N4O5SDegré de pureté :98.97% - 99.88%Couleur et forme :SolidMasse moléculaire :480.54Ref: TM-T4315
1mg44,00€5mg90,00€10mg145,00€25mg268,00€50mg439,00€100mg700,00€200mg954,00€1mL*10mM (DMSO)90,00€AZD7507
CAS :AZD7507 is a CSF-1R inhibitor with an IC50 of 32 nM. AZD7507 has antitumor activity.Formule :C23H27FN6O3Degré de pureté :99.55% - 99.78%Couleur et forme :SolidMasse moléculaire :454.5Ref: TM-T14380
1mg50,00€5mg110,00€10mg161,00€25mg289,00€50mg419,00€100mg583,00€200mg787,00€1mL*10mM (DMSO)127,00€Vimseltinib
CAS :Vimseltinib (DCC-3014) is a c-FMS (CSF-IR) and c-Kit dual inhibitor (IC50s: <0.01 μM and 0.1-1 μM).Formule :C23H25N7O2Degré de pureté :99.05% - 99.57%Couleur et forme :SolidMasse moléculaire :431.49Ref: TM-T10652
1mg87,00€5mg178,00€10mg295,00€25mg505,00€50mg690,00€100mg888,00€1mL*10mM (DMSO)203,00€Linifanib
CAS :Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) andFormule :C21H18FN5ODegré de pureté :98% - 98.24%Couleur et forme :SolidMasse moléculaire :375.4Ref: TM-T2514
5mg48,00€10mg80,00€25mg119,00€50mg178,00€100mg259,00€200mg477,00€500mg772,00€1mL*10mM (DMSO)50,00€Edicotinib HCl
CAS :Edicotinib (JNJ-40346527), an oral CSF1R inhibitor, may block FMS autophosphorylation, impeding tumor cell growth.Formule :C27H36ClN5O2Couleur et forme :SolidMasse moléculaire :498.07cFMS Receptor Inhibitor II
CAS :cFMS Receptor Inhibitor II is a CSF1R kinase inhibitorFormule :C23H20N4ODegré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :368.43Ref: TM-T5586
1mg49,00€2mg65,00€5mg97,00€10mg154,00€25mg255,00€50mg376,00€100mg547,00€1mL*10mM (DMSO)106,00€Pexidartinib
CAS :Pexidartinib (PLX-3397) is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potentialFormule :C20H15ClF3N5Degré de pureté :98.34% - 99.45%Couleur et forme :SolidMasse moléculaire :417.81Ref: TM-T2115
5mg46,00€10mg58,00€25mg90,00€50mg114,00€100mg145,00€200mg192,00€500mg333,00€1mL*10mM (DMSO)49,00€Anumigilimab
CAS :Anumigilimab (CSL-324) is a fully human therapeutic anti-G-CSFR antibody with potential anti-tumor activity for the study of inflammation.Degré de pureté :95.75% (SEC-HPLC) - 98.43% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :143.86 kDaCerdulatinib hydrochloride
CAS :Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others with IC50 < 200 nM.Formule :C20H28ClN7O3SDegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :482Lenzilumab
CAS :Lenzilumab (KB 003) is a humanized GM-CSF neutralizing antibody for the study of COVID-19.Degré de pureté :98.9% (SDS-PAGE); 98.5% (SEC-HPLC) - 98.9% (SDS-PAGE); 98.5% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :146.81 kDaCabiralizumab
CAS :Cabiralizumab is an anti-CSF1R monoclonal antibody that enhances T cell infiltration, inhibits osteoclasts, and is used in RA and immune-oncology research.Degré de pureté :95% - 98.2% (SDS-PAGE); 98.1% (SEC-HPLC)Couleur et forme :LiquidNamilumab
CAS :Namilumab (AMG203) is a humanised IgG1 monoclonal antibody that neutralises GM-CSF. rheumatoid arthritis and active axial spondyloarthritis.Degré de pureté :95%Couleur et forme :LiquidTrabikibart
CAS :Trabikibart (CSL311) is a human βc-specific antibody inhibiting IL-3, GM-CSF and IL-5, regulating eosinophil survival in chronic inflammatory disease research.Degré de pureté :95% - 95.6% (SDS-PAGE); 99.3% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :144.64 kDaCSF1R-IN-19
CAS :CSF1R-IN-19 is a robust inhibitor of CSF1R that influences the exchange of inflammatory factors between TAMs and glioma cells. It holds potential for cancer research [1].Formule :C20H27N7OCouleur et forme :SolidMasse moléculaire :381.47c-Fms-IN-6
CAS :c-Fms-IN-6 is a potent inhibitor of c-FMS (IC50 ≤10 nM for unphosphorylated c-FMS) and also weakly inhibits unphosphorylated c-KIT and PDGFR (IC50: > 1 μM).Formule :C22H25N7O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :419.48c-Fms-IN-9
CAS :c-Fms-IN-9 inhibits c-FMS/uFMS and uKIT with IC50 <0.01μM and 0.1-1μM, from patent WO2014145023A1.Formule :C21H23N7O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :405.45Leustroducsin A
CAS :Leustroducsin A is an inducer of colony-stimulating factors (CSFs) extracted from Streptomyces platensis SANK 60191.Formule :C32H52NO10PCouleur et forme :SolidMasse moléculaire :641.73c-Fms-IN-7
CAS :c-Fms-IN-7 is a cFMS inhibitor (IC50: 18.5 nM).Formule :C26H24N6OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :468.57c-Fms-IN-8
CAS :c-Fms-IN-8 is a colony-stimulating factor-1 receptor (CSF-1R, c-FMS) Type II inhibitor (IC50: 9.1 nM). It is compound 4a in the reference.Formule :C27H30N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :462.54JNJ-28312141
CAS :JNJ-28312141: oral CSF1R/FLT3 inhibitor, potential for treating acute myeloid leukemia, tumors, and bone events.Formule :C26H32N6O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :460.57CSF1R-IN-4
CAS :CSF1R-IN-4, a potent CSF-1R inhibitor, may impact TAM/glioma cell communication, with cancer research potential. (WO2021197276A1, compound 104)Formule :C23H20N6O3Couleur et forme :SolidMasse moléculaire :428.44c-Fms-IN-10
CAS :c-Fms-IN-10 is a thieno[3,2-d]pyrimidine derivative, an FMS kinase inhibitor with IC50 of 2 nM, exhibiting anti-tumor properties.Formule :C22H19N7OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :429.5CSF1R-IN-13
CAS :CSF1R-IN-13: potent cancer research CSF1R inhibitor impacting cell growth regulation.Formule :C21H20N4O3Couleur et forme :SolidMasse moléculaire :376.41CSF1R-IN-8
CAS :CSF1R-IN-8 (Compound 22) is a CSF-1R inhibitor (IC50: 0.012 μM).Formule :C24H22N4O4Couleur et forme :SolidMasse moléculaire :430.46CSF1R-IN-10
CAS :CSF1R-IN-10 (Compound 48) is a CSF-1R inhibitor (IC50: 0.005 μM).Formule :C25H22N4O3Couleur et forme :SolidMasse moléculaire :426.47Leustroducsin C
CAS :Leustroducsin C is an inducer of colony-stimulating factors CSF extracted from Streptomyces platensis SANK 60191.Formule :C34H56NO10PCouleur et forme :SolidMasse moléculaire :669.78CSF1R-IN-14
CAS :CSF1R-IN-14, an isoindolinone derivative, powerfully inhibits CSF1R, with potential in cancer research. See WO2019134662A1, compound 1.Formule :C23H22F3N5OCouleur et forme :SolidMasse moléculaire :441.45CSF1R-IN-12
CAS :CSF1R-IN-12 is an effective CSF1R inhibitor. CSF1R-IN-12 has research potential in cancer diseases.Formule :C21H17F3N4OCouleur et forme :SolidMasse moléculaire :398.38CSF1R-IN-7
CAS :CSF1R-IN-7 is a highly selective CSF-1R inhibitor with good brain penetration for treatment of diseases associated with microglia-mediated neuroinflammation.Formule :C22H22N6O3Degré de pureté :99.41% - 99.93%Couleur et forme :SolidMasse moléculaire :418.45CSF1R-IN-9
CAS :CSF1R-IN-9 (Compound 46) is a CSF-1R inhibitor (IC50: 0.028 μM).Formule :C26H26N4O2Couleur et forme :SolidMasse moléculaire :426.51CSF1R-IN-6
CAS :CSF1R-IN-6, a compound, effectively inhibits macrophage CSF1R essential for survival and differentiation.
Formule :C20H18N8O3Couleur et forme :SolidMasse moléculaire :418.41c-Fms-IN-2
CAS :c-Fms-IN-2 is an inhibitor of c-FMS kinase (IC50 = 24 nM).Formule :C19H21N3O3Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :339.39Ref: TM-T10775
1mg92,00€5mg241,00€10mg355,00€25mg532,00€50mg750,00€100mg1.009,00€1mL*10mM (DMSO)180,00€ABD-295
CAS :ABD-295, a biphenylsulfide derivative, inhibits osteoclasts and prevents bone loss in vitro and in vivo.Formule :C17H19F2NO3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :355.4Sotuletinib dihydrochloride
CAS :Sotuletinib (BLZ945) dihydrochloride is an orally administered, blood-brain barrier-permeable inhibitor specifically targeting CSF1-R with an IC50 of 1 nM.Formule :C20H24Cl2N4O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :471.4IACS-9439
CAS :IACS-9439 is a potent, selective, and orally active inhibitor of CSF1R, exhibiting a K(i) of 1 nM.Formule :C23H26ClN7O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :516.02c-Fms-IN-1
CAS :c-Fms-IN-1 is an inhibitor of c-FMS kinase (IC50 = 0.8 nM).Formule :C22H27N5O2Degré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :393.48Chiauranib
CAS :Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.
Formule :C27H21N3O3Degré de pureté :99.22%Couleur et forme :SolidMasse moléculaire :435.47c-Fms-IN-3
CAS :c-Fms-IN-3 is a novel inhibitor of the c-FMS and can be used in studies about antirheumatic and anti-inflammatory diseases.Formule :C23H30N6ODegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :406.52Ref: TM-T10649
1mg52,00€5mg105,00€10mg161,00€25mg264,00€50mg358,00€100mg522,00€1mL*10mM (DMSO)110,00€c-Fms-IN-13
CAS :c-Fms-IN-13 (compound 14) is a potent FMS kinase inhibitor (IC50= 17 nM). c-Fms-IN-13 is an anti-inflammatory agent.Formule :C22H26N4O2Degré de pureté :99.93% - 99.97%Couleur et forme :SolidMasse moléculaire :378.47Pimicotinib
CAS :Pimicotinib (ABSK021) is a potent CSF1R inhibitor with antitumor activity and can be used to study advanced solid tumors.Formule :C22H24N6O3Degré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :420.46Ref: TM-T79157
1mg52,00€5mg111,00€10mg170,00€25mg329,00€50mg528,00€100mg843,00€1mL*10mM (DMSO)156,00€CSF1R-IN-3
CAS :CSF1R-IN-3 is an orally effective CSF-1R inhibitor with an IC50 value of 2.1 nM.Formule :C30H38N8O4Degré de pureté :98.4%Couleur et forme :SolidMasse moléculaire :574.67Ref: TM-T64066
1mg101,00€5mg245,00€10mg358,00€25mg665,00€50mg973,00€100mg1.395,00€1mL*10mM (DMSO)309,00€Ataquimast
CAS :Ataquimast is used in curing advanced receptor-positive breast cancer.Formule :C11H14ClN3ODegré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :239.7Ref: TM-T30190
1mg64,00€5mg129,00€10mg188,00€25mg299,00€50mg427,00€100mg575,00€200mg750,00€1mL*10mM (DMSO)116,00€JTE-952
CAS :JTE-952: oral, selective Type II CSF-1R inhibitor, IC50 = 13 nM for CSF1R, 261 nM for TrkA, effective in mouse arthritis model.Formule :C30H34N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :518.6c-Fms-IN-14
CAS :c-Fms-IN-14 (Example 76) is a potent inhibitor of the c-Fms kinase with an IC50 of 4 nM, utilized in cancer and autoimmune disease research [1].Formule :C26H24N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :436.51Axl/Mer/CSF1R-IN-2
CAS :Axl/Mer/CSF1R-IN-2 (Comp 4) serves as an inhibitor for Axl, Mer, and CSF1R [1].Formule :C24H22F3N5O5Couleur et forme :SolidMasse moléculaire :517.46CSF1R-IN-5
CAS :CSF1R-IN-5: Potent CSF1R inhibitor, may alter TAM/glioma inflammatory exchanges, potential cancer research tool. (WO2021197276A1, Compound 11)Formule :C22H19N7O3Couleur et forme :SolidMasse moléculaire :429.43Axl/Mer/CSF1R-IN-1
CAS :Axl/Mer-IN-1 is a compound that functions as an inhibitor for Axl/Mer receptor tyrosine kinase (Axl/Mer RTK) and CSF1R, exhibiting dissociation constants (Kds)Formule :C25H24F3N5O5Couleur et forme :SolidMasse moléculaire :531.48Adrixetinib
CAS :Adrixetinib is an inhibitor of protein tyrosine kinase with antineoplastic activity .Formule :C25H24F3N5O5Couleur et forme :SolidMasse moléculaire :531.48
