VEGFR
Les inhibiteurs du récepteur du facteur de croissance endothélial vasculaire (VEGFR) sont des composés qui bloquent la signalisation du VEGFR, un récepteur clé dans la voie VEGF, cruciale pour l'angiogenèse. Les inhibiteurs de VEGFR empêchent la formation de nouveaux vaisseaux sanguins qui fournissent des nutriments et de l'oxygène aux tumeurs, inhibant ainsi la croissance tumorale. Ces inhibiteurs sont largement utilisés en thérapie et en recherche contre le cancer pour étudier les mécanismes de l'angiogenèse et développer des traitements anticancéreux. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de VEGFR de haute qualité pour soutenir vos recherches en oncologie, biologie vasculaire et angiogenèse.
244 produits trouvés pour "VEGFR"
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Tesevatinib
CAS :Tesevatinib (XL-647) is an oral, multi-targeted tyrosine kinase inhibitor.Cost-effective and quality-assured.Formule :C24H25Cl2FN4O2Degré de pureté :97.89% - 98.66%Couleur et forme :SolidMasse moléculaire :491.39NVP-ACC789
CAS :ACC-789 (NVP-ACC789 (ZK202650); ZK-202650) is an effective, specific and orally active inhibitor of the VEGF receptor tyrosine kinases.
Formule :C21H17BrN4Degré de pureté :99.44% - 99.63%Couleur et forme :SolidMasse moléculaire :405.29CZC-8004
CAS :CZC-8004 (CZC-00008004) is a pan-kinase(ABL kinase) inhibitor and binds a range of tyrosine kinases.
Formule :C17H16FN5Degré de pureté :99.29%Couleur et forme :SolidMasse moléculaire :309.34Nintedanib
CAS :Nintedanib (Intedanib) is a triple vascular kinase inhibitor that inhibits VEGFR1, VEGFR2, and VEGFR3 (IC50=34/13/13 nM), FGFR1, FGFR2, and FGFR3 (IC50=69/37/Formule :C31H33N5O4Degré de pureté :98% - 99.92%Couleur et forme :SolidMasse moléculaire :539.62Ref: TM-T1777
5mg43,00€1mL*10mM (DMSO)52,00€1ml*10 (DMSO)54,00€10mg56,00€50mg66,00€100mg96,00€200mg134,00€15g815,00€Mollugin
CAS :Mollugin could be a JAK2 inhibitor, anti-inflammatory, chemotherapeutic agent in OSCCs, bone disorder therapy, and modulates HER2 in cancer.Formule :C17H16O4Degré de pureté :99.87% - ≥95%Couleur et forme :SolidMasse moléculaire :284.31Cabozantinib hydrochloride
CAS :Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6Formule :C28H25ClFN3O5Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :537.96Ref: TM-T5164
1mg42,00€2mg52,00€5mg65,00€10mg92,00€25mg160,00€50mg235,00€100mg330,00€200mg538,00€500mg860,00€JK-P3
CAS :JK-P3: a pyrazole inhibitor of VEGFR-2 (IC50: 7.8 μM), stalls FGFR 1/3 in vitro, halts HUVEC wound healing/tube formation, not cell growth.Formule :C18H17N3O3Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :323.35Dovitinib
CAS :Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.
Formule :C21H21FN6ODegré de pureté :99.35% - 99.92%Couleur et forme :SolidMasse moléculaire :392.43ODM-203
CAS :ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor ImmunityFormule :C26H21F2N5O2SDegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :505.54Sitravatinib
CAS :Sitravatinib (MGCD516) (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRα/β, PDGFR, andFormule :C33H29F2N5O4SDegré de pureté :98.9% - 99.85%Couleur et forme :SolidMasse moléculaire :629.68Ref: TM-T4349
5mg49,00€1mL*10mM (DMSO)69,00€10mg74,00€25mg130,00€50mg200,00€100mg319,00€200mg507,00€500mg800,00€4SC-203
CAS :4SC-203 is a multi-kinase inhibitor with potential anti-tumor activity.Cost-effective and quality-assured.Formule :C33H38N8O4SDegré de pureté :99.52% - 99.84%Couleur et forme :SolidMasse moléculaire :642.77hVEGF-IN-1
CAS :hVEGF-IN-1 inhibits human VEGF-A translation and has antitumor activity.Formule :C34H43N7O2Degré de pureté :99.76% - >99.99%Couleur et forme :SolidMasse moléculaire :581.75ENMD-2076
CAS :ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.Formule :C21H25N7Degré de pureté :97.63% - ≥95%Couleur et forme :SolidMasse moléculaire :375.47SPHINX31
CAS :SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).Formule :C27H24F3N5O2Degré de pureté :99.3% - 99.87%Couleur et forme :SolidMasse moléculaire :507.51Ref: TM-T5194
1mg38,00€5mg79,00€10mg92,00€1mL*10mM (DMSO)93,00€25mg170,00€50mg255,00€100mg408,00€500mg945,00€AST 487
CAS :AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.Formule :C26H30F3N7O2Degré de pureté :98.17% - 99.56%Couleur et forme :SolidMasse moléculaire :529.56Ref: TM-T4053
1mg34,00€2mg49,00€5mg74,00€1mL*10mM (DMSO)87,00€10mg113,00€25mg177,00€50mg334,00€100mg500,00€500mg1.099,00€Tivozanib hydrochloride hydrate
CAS :Tivozanib hydrochloride hydrate (AV-951 hydrochloride hydrate) is a VEGFR tyrosine kinase inhibitor that inhibits VEGFR-1, VEGFR-2, VEGFR-3 .Formule :C22H22Cl2N4O6Degré de pureté :98.66% - 99.99%Couleur et forme :SolidMasse moléculaire :509.34Toceranib
CAS :Toceranib phosphate, orally active, inhibits RTK, PDGFR, VEGFR, Kit; Kis 5 nM PDGFRβ, 6 nM KDR; has antitumor effects.Formule :C22H25FN4O2Degré de pureté :97.62%Couleur et forme :SolidMasse moléculaire :396.46Brivanib (alaninate)
CAS :Brivanib Alaninate (BMS-582664) is an alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic effect.Formule :C22H24FN5O4Degré de pureté :99.46% - 99.66%Couleur et forme :SolidMasse moléculaire :441.46BIBF 1202
CAS :BIBF 1202 is a VEGFR2 kinase inhibitor (IC50 = 62 nM).Formule :C30H31N5O4Degré de pureté :98.04%Couleur et forme :SolidMasse moléculaire :525.6(Rac)-SAR131675
CAS :(Rac)-SAR131675 is an effective and specific VEGFR-3 inhibitor, which inhibited VEGFR-3 tyrosine kinase activity and VEGFR-3 autophosphorylation in HEK cells.Formule :C18H22N4O4Degré de pureté :98.73% - 99.1%Couleur et forme :SolidMasse moléculaire :358.39BMS-690514
CAS :BMS-690514 is a potent and orally active inhibitor of EGFR and VEGFR. It has IC50s of 5, 20 and 60 nM for EGFR, HER 2 and HER 4, respectively.Formule :C19H24N6O2Degré de pureté :99.08%Couleur et forme :SolidMasse moléculaire :368.43Tarcocimab
CAS :Tarcocimab (OG1953) is a humanized IgG1 monoclonal antibody targeting VEGFA, researched for RVO and wet AMD.Couleur et forme :LiquidZM323881 hydrochloride
CAS :ZM323881 hydrochloride (ZM 323881 HCl) is a potent and selective VEGFR2 inhibitor.Formule :C22H19ClFN3O2Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :411.86Ref: TM-T1991
1mg34,00€5mg66,00€1mL*10mM (DMSO)69,00€10mg96,00€25mg225,00€50mg369,00€100mg550,00€200mg780,00€Bucillamine
CAS :Bucillamine (DE019) protects against Ischemia/reperfusion injury in high-risk organ transplants and inhibits the production of VEGF.Formule :C7H13NO3S2Degré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :223.31E3330
CAS :E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.Formule :C21H30O6Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :378.46Naphazoline
CAS :Naphazoline (Naphcon-a) is a sympathomimetic compound with marked alpha adrenergic activity.Formule :C14H14N2Degré de pureté :99.79%Couleur et forme :White Crystalline Powder SolidMasse moléculaire :210.27VEGFR-2-IN-6
CAS :VEGFR-2-IN-6 (WO 02/059110, example 64) is a potent inhibitor of VEGFR2, a crucial receptor involved in the regulation of angiogenesis [1].Formule :C20H21N7O2SDegré de pureté :99.01%Couleur et forme :SolidMasse moléculaire :423.49DMH4
CAS :DMH4 is a potent and selective inhibitor of VEGFR2 with an IC50 of 0.16 µM.Formule :C24H24N4O2Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :400.47AMG-Tie2-1
CAS :AMG-Tie2-1 is a Tie2 and VEGFR2 inhibitor with anticancer and antitumor activity for the study of cardiovascular disease and cancer.Formule :C25H20F3N5O2Degré de pureté :98.9%Couleur et forme :SolidMasse moléculaire :479.45Chiauranib
CAS :Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.Formule :C27H21N3O3Degré de pureté :99.22%Couleur et forme :SolidMasse moléculaire :435.47Ref: TM-T35570
1mg66,00€5mg144,00€1mL*10mM (DMSO)157,00€10mg245,00€25mg492,00€50mg710,00€100mg973,00€VEGFR-3-IN-1
CAS :VEGFR-3-IN-1, a potent VEGFR3 inhibitor (IC50=110.4 nM), hinders tumor growth and VEGFR3 signaling, affecting HDLEC and MDA-MB cell proliferation/migration.Formule :C29H29ClF3N7OSDegré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :616.1(E)-FeCP-oxindole
CAS :(E)-FeCP-oxindole 是一种 VEGFR2 抑制剂，IC50 为 214 nM。Formule :C19H15FeNODegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :329.17Pz-1
CAS :Pz-1 is an inhibitor of VEGFR2 and RET (rearranged during transfection) tyrosine kinase that blocks the blood supply required for RET-stimulated growth.Formule :C26H26N6O2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :454.52(Z)-FeCP-oxindole
CAS :(Z)-FeCP-oxindole is a selective inhibitor of VEGFR2 with an IC50 of 200 nM for human. (Z)-FeCP-oxindole shows anticancer activity.Formule :C19H15FeNODegré de pureté :99.63% - 99.84%Couleur et forme :SolidMasse moléculaire :329.17VEGFR-2-IN-9
CAS :VEGFR-2-IN-9 (KDR-in-4) is a potent KDR/VEGFR2 inhibitor (IC50: 7 nM). It can be used to study breast cancer.Formule :C23H25N3O3Degré de pureté :97.19%Couleur et forme :SolidMasse moléculaire :391.46VEGFR2-IN-3
CAS :VEGFR2-IN-3 (compound 385) is a potent inhibitor of VEGFR2 [1].Formule :C26H28ClN5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :509.98VEGFR-2-IN-37
CAS :VEGFR-2-IN-37 (compound 12), a VEGFR-2 inhibitor, exhibits an inhibition rate of approximately 56.9 μM at a concentration of 200 μM.Formule :C18H16N2O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :324.4Brolucizumab
CAS :Brolucizumab (anti-VEGF-A scFv) potently blocks VEGF-A to reduce neovascularization in wet AMD, with picomolar binding affinity.Degré de pureté :95%Couleur et forme :LiquidMasse moléculaire :~150 kDaTG 100572 Hydrochloride
CAS :TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.Formule :C26H27Cl2N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :512.43Tyrphostin AG1433
CAS :Tyrphostin AG1433 (AG1433) is an inhibitor of tyrosine kinases and also a dual inhibitor of PDGFRβ(IC50s = 5.0 μM) and VEGFR-2 (Flk-1/KDR)(IC50s = 9.3 μM).Formule :C16H14N2O2Degré de pureté :98.47%Couleur et forme :SolidMasse moléculaire :266.29VEGFR/PDGFR-IN-1
CAS :VEGFR/PDGFR-IN-1 (Compound 1) is an inhibitor of VEGFR with an IC50 of 0.4 μM. It can inhibit angiogenesis in HUVEC cells and holds promise for impeding tumor growth and metastasis.Formule :C17H21N5O3Couleur et forme :SolidMasse moléculaire :343.38VEGFR-2-IN-38
CAS :VEGFR-2-IN-38 (compound 3) acts as a potential inhibitor of the vascular endothelial growth factor receptor-2 [1].Formule :C17H12N4SCouleur et forme :SolidMasse moléculaire :304.37VEGFR-2-IN-65
CAS :VEGFR-2-IN-65 (Compound 07) functions as a VEGFR-2 inhibitor. It forms hydrogen bonds with Cys180 and can inhibit tube formation in HUVECs.Formule :C21H18N2O3Couleur et forme :SolidMasse moléculaire :346.379VEGFR2-IN-1
CAS :VEGFR2-IN-1 is a VEGFR2 inhibitor with antitumor activity used in the study of breast cancer.Formule :C22H18N6SDegré de pureté :98.15%Couleur et forme :SolidMasse moléculaire :398.48
