VEGFR
Les inhibiteurs du récepteur du facteur de croissance endothélial vasculaire (VEGFR) sont des composés qui bloquent la signalisation du VEGFR, un récepteur clé dans la voie VEGF, cruciale pour l'angiogenèse. Les inhibiteurs de VEGFR empêchent la formation de nouveaux vaisseaux sanguins qui fournissent des nutriments et de l'oxygène aux tumeurs, inhibant ainsi la croissance tumorale. Ces inhibiteurs sont largement utilisés en thérapie et en recherche contre le cancer pour étudier les mécanismes de l'angiogenèse et développer des traitements anticancéreux. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de VEGFR de haute qualité pour soutenir vos recherches en oncologie, biologie vasculaire et angiogenèse.
268 produits trouvés pour "VEGFR"
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Cabozantinib S-malate
CAS :<p>Cabozantinib S-malate (XL184) is the salt form of cabozantinib, an orally bioavailable, small molecule RTK inhibitor with potential antineoplastic activity.</p>Formule :C32H30FN3O10Degré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :635.59SU5214
CAS :<p>SU5214 is a modulator of tyrosine kinase signal transduction.</p>Formule :C16H13NO2Degré de pureté :99.45% - 99.55%Couleur et forme :SolidMasse moléculaire :251.28UNC0064-12 hydrochloride (1430089-64-7(free base))
<p>UNC0064-12 hydrochloride is an inhibitor of VEGFR2.</p>Formule :C19H25ClN8Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :400.91Toceranib Phosphate
CAS :<p>Toceranib Phosphate (SU11654 phosphate), is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family.</p>Formule :C22H28FN4O6PDegré de pureté :98.56%Couleur et forme :SolidMasse moléculaire :494.45Ramucirumab
CAS :<p>Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors.</p>Formule :C285H434N74O88S2Degré de pureté :98.2% (SDS-PAGE); 99.2% (SEC-HPLC) - 99.20%Couleur et forme :LiquidMasse moléculaire :143.77 kDaNingetinib
CAS :<p>Ningetinib (CT-053) (CT053PTSA) is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.</p>Formule :C31H29FN4O5Degré de pureté :99.95% - 99.98%Couleur et forme :SolidMasse moléculaire :556.58Orobol
CAS :<p>Orobol (3’,4’,5,7-tetrahydroxy-isoflavon) is an inhibitor of tyrosine-specific protein kinase and phosphatidylinositol turnover.</p>Formule :C15H10O6Degré de pureté :98% - 98%Couleur et forme :SolidMasse moléculaire :286.24XL 999
CAS :<p>Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor（KDR, Flt-1, FGFR1 and PDGFRα with IC50s of 4nM, 20nM, 4nM, 2 nM ,respectively）</p>Formule :C26H28FN5ODegré de pureté :98.24% - 99.55%Couleur et forme :SolidMasse moléculaire :445.53Cabozantinib
CAS :<p>Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM).</p>Formule :C28H24FN3O5Degré de pureté :99.68% - 99.88%Couleur et forme :SolidMasse moléculaire :501.51BFH772
CAS :<p>BFH772, a BAW2881 analogue, selectively inhibits VEGFR2 (IC50: 3 nM) and blocks RET, PDGFR, KIT phosphorylation (IC50: 30-160 nM).</p>Formule :C23H16F3N3O3Degré de pureté :97.71% - 99.36%Couleur et forme :SolidMasse moléculaire :439.39Su1498
CAS :<p>Su1498 (Tyrphostin SU 1498) is a selective inhibitor of the VEGF receptor 2, having negligible activity at several other serine/threonine and tyrosine kinases.</p>Formule :C25H30N2O2Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :390.52Regorafenib Hydrochloride
CAS :<p>Regorafenib HCl (BAY73-4506) is an oral inhibitor targeting angiogenic, stromal, and cancer kinases with strong antitumor effects.</p>Formule :C21H16Cl2F4N4O3Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :519.28Tesevatinib
CAS :<p>Tesevatinib (XL-647) is an oral, multi-targeted tyrosine kinase inhibitor.Cost-effective and quality-assured.</p>Formule :C24H25Cl2FN4O2Degré de pureté :97.89% - 98.66%Couleur et forme :SolidMasse moléculaire :491.39NVP-ACC789
CAS :<p>ACC-789 (NVP-ACC789 (ZK202650); ZK-202650) is an effective, specific and orally active inhibitor of the VEGF receptor tyrosine kinases.</p>Formule :C21H17BrN4Degré de pureté :99.44% - 99.63%Couleur et forme :SolidMasse moléculaire :405.29Alectinib
CAS :<p>Alectinib (RG-7853) is an ALK inhibitor that is selective, orally active, and ATP-competitive. Alectinib has antitumor activity. Cost-effective and quality-assured.</p>Formule :C30H34N4O2Degré de pureté :98% - 99.38%Couleur et forme :SolidMasse moléculaire :482.62BMS-2
CAS :<p>BMS-2 is a Met/Flt-3/VEGFR2 tyrosine kinase inhibitor.</p>Formule :C25H16F2N4O3Degré de pureté :98.33%Couleur et forme :SolidMasse moléculaire :458.42Nintedanib
CAS :<p>Nintedanib (Intedanib) is a triple vascular kinase inhibitor that inhibits VEGFR1, VEGFR2, and VEGFR3 (IC50=34/13/13 nM), FGFR1, FGFR2, and FGFR3 (IC50=69/37/</p>Formule :C31H33N5O4Degré de pureté :98% - 99.92%Couleur et forme :SolidMasse moléculaire :539.62Mollugin
CAS :<p>Mollugin could be a JAK2 inhibitor, anti-inflammatory, chemotherapeutic agent in OSCCs, bone disorder therapy, and modulates HER2 in cancer.</p>Formule :C17H16O4Degré de pureté :99.87% - ≥95%Couleur et forme :SolidMasse moléculaire :284.31Cabozantinib hydrochloride
CAS :<p>Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6</p>Formule :C28H25ClFN3O5Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :537.96JK-P3
CAS :<p>JK-P3: a pyrazole inhibitor of VEGFR-2 (IC50: 7.8 μM), stalls FGFR 1/3 in vitro, halts HUVEC wound healing/tube formation, not cell growth.</p>Formule :C18H17N3O3Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :323.35Dovitinib
CAS :<p>Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.</p>Formule :C21H21FN6ODegré de pureté :99.35% - 99.92%Couleur et forme :SolidMasse moléculaire :392.43ODM-203
CAS :<p>ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor Immunity</p>Formule :C26H21F2N5O2SDegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :505.54Sitravatinib
CAS :<p>Sitravatinib (MGCD516) (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRα/β, PDGFR, and</p>Formule :C33H29F2N5O4SDegré de pureté :98.9% - 99.85%Couleur et forme :SolidMasse moléculaire :629.684SC-203
CAS :<p>4SC-203 is a multi-kinase inhibitor with potential anti-tumor activity.Cost-effective and quality-assured.</p>Formule :C33H38N8O4SDegré de pureté :96.4% - 99.67%Couleur et forme :SolidMasse moléculaire :642.77hVEGF-IN-1
CAS :<p>hVEGF-IN-1 inhibits human VEGF-A translation and has antitumor activity.</p>Formule :C34H43N7O2Degré de pureté :99.76% - >99.99%Couleur et forme :SolidMasse moléculaire :581.75ENMD-2076
CAS :<p>ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.</p>Formule :C21H25N7Degré de pureté :97.63% - ≥95%Couleur et forme :SolidMasse moléculaire :375.47SPHINX31
CAS :<p>SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).</p>Formule :C27H24F3N5O2Degré de pureté :98.81% - 99.3%Couleur et forme :SolidMasse moléculaire :507.51AST 487
CAS :<p>AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.</p>Formule :C26H30F3N7O2Degré de pureté :98.17% - 99.56%Couleur et forme :SolidMasse moléculaire :529.56Tivozanib hydrochloride hydrate
CAS :<p>Tivozanib hydrochloride hydrate (AV-951 hydrochloride hydrate) is a VEGFR tyrosine kinase inhibitor that inhibits VEGFR-1, VEGFR-2, VEGFR-3 .</p>Formule :C22H22Cl2N4O6Degré de pureté :98.66%Couleur et forme :SolidMasse moléculaire :509.34Toceranib
CAS :<p>Toceranib phosphate, orally active, inhibits RTK, PDGFR, VEGFR, Kit; Kis 5 nM PDGFRβ, 6 nM KDR; has antitumor effects.</p>Formule :C22H25FN4O2Degré de pureté :97.14%Couleur et forme :SolidMasse moléculaire :396.46(Rac)-SAR131675
CAS :<p>(Rac)-SAR131675 is an effective and specific VEGFR-3 inhibitor, which inhibited VEGFR-3 tyrosine kinase activity and VEGFR-3 autophosphorylation in HEK cells.</p>Formule :C18H22N4O4Degré de pureté :98.34% - 99.1%Couleur et forme :SolidMasse moléculaire :358.39BIBF 1202
CAS :<p>BIBF 1202 is a VEGFR2 kinase inhibitor (IC50 = 62 nM).</p>Formule :C30H31N5O4Degré de pureté :98.04%Couleur et forme :SolidMasse moléculaire :525.6BMS-690514
CAS :<p>BMS-690514 is a potent and orally active inhibitor of EGFR and VEGFR. It has IC50s of 5, 20 and 60 nM for EGFR, HER 2 and HER 4, respectively.</p>Formule :C19H24N6O2Degré de pureté :99.08%Couleur et forme :SolidMasse moléculaire :368.43Brivanib (alaninate)
CAS :<p>Brivanib Alaninate (BMS-582664) is an alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic effect.</p>Formule :C22H24FN5O4Degré de pureté :99.46% - 99.66%Couleur et forme :SolidMasse moléculaire :441.46Anti-Mouse VEGFR-2 Antibody (DC101)
<p>Anti-Mouse VEGFR-2 Antibody (DC101) is a rat-derived monoclonal antibody against mouse VEGFR2/KDR/Flk-1, serving as a mouse analogue of ramucirumab.</p>Degré de pureté :99%Couleur et forme :Odour LiquidTarcocimab
CAS :<p>Tarcocimab (OG1953) is a humanized IgG1 monoclonal antibody targeting VEGFA, researched for RVO and wet AMD.</p>Couleur et forme :LiquidZM323881 hydrochloride
CAS :<p>ZM323881 hydrochloride (ZM 323881 HCl) is a potent and selective VEGFR2 inhibitor.</p>Formule :C22H19ClFN3O2Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :411.86Dovitinib Dilactic Acid
CAS :<p>Dovitinib dilactic acid: multitarget RTK inhibitor for FLT3/c-Kit (IC50=1-2 nM), FGFR1/3, VEGFR1-4 (IC50=8-13 nM), less effective on InsR, EGFR. Phase 4.</p>Formule :C21H21FN6O·2C3H6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :572.59Bucillamine
CAS :<p>Bucillamine (DE019) protects against Ischemia/reperfusion injury in high-risk organ transplants and inhibits the production of VEGF.</p>Formule :C7H13NO3S2Degré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :223.31E3330
CAS :<p>E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.</p>Formule :C21H30O6Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :378.46GW843682X
CAS :<p>GW843682X (GW843682) is a selective and ATP-competitive inhibitor of PLK1 and PLK3 (IC50s = 2.2 nM and 9.1 nM).</p>Formule :C22H18F3N3O4SDegré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :477.46CP-547632
CAS :<p>CP-547632 is an oral ATP-competitive inhibitor of VEGFR-2/FGF kinase with IC50s of 11/9 nM, highly selective, has antitumor activity.</p>Formule :C20H24BrF2N5O3SDegré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :532.4DMH4
CAS :<p>DMH4 is a potent and selective inhibitor of VEGFR2 with an IC50 of 0.16 µM.</p>Formule :C24H24N4O2Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :400.47AMG-Tie2-1
CAS :<p>AMG-Tie2-1 is a Tie2 and VEGFR2 inhibitor with anticancer and antitumor activity for the study of cardiovascular disease and cancer.</p>Formule :C25H20F3N5O2Degré de pureté :98.9%Couleur et forme :SolidMasse moléculaire :479.45VEGFR-2-IN-6
CAS :<p>VEGFR-2-IN-6 (WO 02/059110, example 64) is a potent inhibitor of VEGFR2, a crucial receptor involved in the regulation of angiogenesis [1].</p>Formule :C20H21N7O2SDegré de pureté :99.01%Couleur et forme :SolidMasse moléculaire :423.49MMPP
CAS :<p>MMPP is a VEGFR2 inhibitor with anti-inflammatory activity, inhibits STAT3 , inhibits angiogenesis, and can be used to alleviate myocardial injury.</p>Formule :C17H18O3Degré de pureté :99.31% - 99.83%Couleur et forme :SolidMasse moléculaire :270.32Naphazoline
CAS :<p>Naphazoline (Naphcon-a) is a sympathomimetic compound with marked alpha adrenergic activity.</p>Formule :C14H14N2Degré de pureté :99.79%Couleur et forme :White Crystalline Powder SolidMasse moléculaire :210.27Ansornitinib
CAS :<p>Ansornitinib (ANG-3070) is a KDR and PDGF receptor inhibitor with antifibrotic activity for the study of diseases caused by abnormal or excessive fibrosis.</p>Formule :C30H32N6O4Couleur et forme :SolidMasse moléculaire :540.61CGP60474
CAS :<p>CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC.</p>Formule :C18H18ClN5ODegré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :355.82AMPK-IN-3
CAS :<p>AMPK-IN-3: potent, selective AMPK (α2/α1) & KDR inhibitor; IC50: 60.7/107/3820 nM; anticancer in K562 cells.</p>Formule :C25H33N5O3Degré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :451.56VEGFR-3-IN-1
CAS :<p>VEGFR-3-IN-1, a potent VEGFR3 inhibitor (IC50=110.4 nM), hinders tumor growth and VEGFR3 signaling, affecting HDLEC and MDA-MB cell proliferation/migration.</p>Formule :C29H29ClF3N7OSDegré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :616.1Pz-1
CAS :<p>Pz-1 is an inhibitor of VEGFR2 and RET (rearranged during transfection) tyrosine kinase that blocks the blood supply required for RET-stimulated growth.</p>Formule :C26H26N6O2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :454.52Chiauranib
CAS :<p>Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.</p>Formule :C27H21N3O3Degré de pureté :99.22%Couleur et forme :SolidMasse moléculaire :435.47(Z)-FeCP-oxindole
CAS :<p>(Z)-FeCP-oxindole is a selective inhibitor of VEGFR2 with an IC50 of 200 nM for human. (Z)-FeCP-oxindole shows anticancer activity.</p>Formule :C19H15FeNODegré de pureté :99.63% - 99.84%Couleur et forme :SolidMasse moléculaire :329.17(E)-FeCP-oxindole
CAS :<p>(E)-FeCP-oxindole 是一种 VEGFR2 抑制剂，IC50 为 214 nM。</p>Formule :C19H15FeNODegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :329.17Tyrphostin AG1433
CAS :<p>Tyrphostin AG1433 (AG1433) is an inhibitor of tyrosine kinases and also a dual inhibitor of PDGFRβ(IC50s = 5.0 μM) and VEGFR-2 (Flk-1/KDR)(IC50s = 9.3 μM).</p>Formule :C16H14N2O2Degré de pureté :98.47%Couleur et forme :SolidMasse moléculaire :266.29TIE-2/VEGFR-2 kinase-IN-5
CAS :<p>TIE-2/VEGFR-2 kinase-IN-5 is a TIE-2 and VEGFR-2 tyrosine kinase receptor inhibitor commonly used in biomedical research related to angiogenesis.</p>Formule :C21H13F6N5O2Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :481.35Brolucizumab
CAS :<p>Brolucizumab (anti-VEGF-A scFv) potently blocks VEGF-A to reduce neovascularization in wet AMD, with picomolar binding affinity.</p>Degré de pureté :95%Couleur et forme :LiquidTG 100572 Hydrochloride
CAS :<p>TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.</p>Formule :C26H27Cl2N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :512.43AKB-6899
CAS :<p>AKB-6899 is an inhibitor of prolyl hydroxylase domain 3 (PHD3) and increases the soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated</p>Formule :C14H11FN2O4Degré de pureté :97.87%Couleur et forme :SolidMasse moléculaire :290.25VEGFR-2-IN-9
CAS :<p>VEGFR-2-IN-9 (KDR-in-4) is a potent KDR/VEGFR2 inhibitor (IC50: 7 nM). It can be used to study breast cancer.</p>Formule :C23H25N3O3Degré de pureté :97.19%Couleur et forme :SolidMasse moléculaire :391.46VEGFR-2-IN-37
CAS :<p>VEGFR-2-IN-37 (compound 12), a VEGFR-2 inhibitor, exhibits an inhibition rate of approximately 56.9 μM at a concentration of 200 μM.</p>Formule :C18H16N2O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :324.4VEGFR2-IN-3
CAS :<p>VEGFR2-IN-3 (compound 385) is a potent inhibitor of VEGFR2 [1].</p>Formule :C26H28ClN5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :509.98WAY-600
CAS :<p>WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM; blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) but not P-AKT(T308).</p>Formule :C28H30N8ODegré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :494.59VEGFR2-IN-1
CAS :<p>VEGFR2-IN-1 is a VEGFR2 inhibitor with antitumor activity used in the study of breast cancer.</p>Formule :C22H18N6SDegré de pureté :98.15%Couleur et forme :SolidMasse moléculaire :398.48Lucitanib dihydrochloride
CAS :<p>Lucitanib dihydrochloride (E-3810 dihydrochloride) is an efficient VEGFR1-3, FGFR1-3, and PDGFRalpha/β inhibitor, used in metastatic breast cancer research.</p>Formule :C26H27Cl2N3O4Couleur et forme :SolidMasse moléculaire :516.42VEGFR/PDGFR-IN-1
CAS :<p>VEGFR/PDGFR-IN-1 (Compound 1) is an inhibitor of VEGFR with an IC50 of 0.4 μM. It can inhibit angiogenesis in HUVEC cells and holds promise for impeding tumor growth and metastasis.</p>Formule :C17H21N5O3Couleur et forme :SolidMasse moléculaire :343.38VEGFR-2-IN-65
CAS :<p>VEGFR-2-IN-65 (Compound 07) functions as a VEGFR-2 inhibitor. It forms hydrogen bonds with Cys180 and can inhibit tube formation in HUVECs.</p>Formule :C21H18N2O3Couleur et forme :SolidMasse moléculaire :346.379
